LOCUS       DAVBCA010000001        78991 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.001, whole genome shotgun sequence.
ACCESSION   DAVBCA010000001 DAVBCA010000000
VERSION     DAVBCA010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 78991)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 78991)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..78991
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.001"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(48..1937)
                     /locus_tag="VQU19_000001"
     CDS             complement(48..1937)
                     /locus_tag="VQU19_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HET2479336.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKVQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFREGTIEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVREKDQSKQLVTWVLPSILSISLLLSVCFYFIYRRKTTPSVK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSSFEKDCLNLAFSGKKEETLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGGEKALQVGMG
                     ALTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDQAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSLFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            2075..3640
                     /locus_tag="VQU19_000002"
     CDS             2075..3640
                     /locus_tag="VQU19_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HET2479337.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKKPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKAIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMCKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            3640..4404
                     /locus_tag="VQU19_000003"
     CDS             3640..4404
                     /locus_tag="VQU19_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET2479338.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEEIAKENLEKVGMGERYWQARPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLILNENQRAN"
     gene            complement(4603..4818)
                     /locus_tag="VQU19_000004"
     CDS             complement(4603..4818)
                     /locus_tag="VQU19_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2479339.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNHEKFED"
     gene            complement(5689..6939)
                     /gene="ilvA"
                     /locus_tag="VQU19_000005"
     CDS             complement(5689..6939)
                     /gene="ilvA"
                     /locus_tag="VQU19_000005"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HET2479340.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(6989..7345)
                     /locus_tag="VQU19_000006"
     CDS             complement(6989..7345)
                     /locus_tag="VQU19_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HET2479341.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            complement(7583..7819)
                     /locus_tag="VQU19_000007"
     CDS             complement(7583..7819)
                     /locus_tag="VQU19_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2479342.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERAGATKSARYIAKWILRNKKH"
     gene            complement(7926..8948)
                     /gene="ilvC"
                     /locus_tag="VQU19_000008"
     CDS             complement(7926..8948)
                     /gene="ilvC"
                     /locus_tag="VQU19_000008"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HET2479343.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVVEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(9014..9490)
                     /gene="ilvN"
                     /locus_tag="VQU19_000009"
     CDS             complement(9014..9490)
                     /gene="ilvN"
                     /locus_tag="VQU19_000009"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HET2479344.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(9483..11183)
                     /locus_tag="VQU19_000010"
     CDS             complement(9483..11183)
                     /locus_tag="VQU19_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HET2479345.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            complement(11384..13051)
                     /locus_tag="VQU19_000011"
     CDS             complement(11384..13051)
                     /locus_tag="VQU19_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HET2479346.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDTVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(13054..13419)
                     /locus_tag="VQU19_000012"
     CDS             complement(13054..13419)
                     /locus_tag="VQU19_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET2479347.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(13576..13764)
                     /locus_tag="VQU19_000013"
     CDS             complement(13576..13764)
                     /locus_tag="VQU19_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HET2479348.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(13880..14056)
                     /locus_tag="VQU19_000014"
     CDS             complement(13880..14056)
                     /locus_tag="VQU19_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HET2479349.1"
                     /translation="MDSDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLIN
                     DGMWRAENVTQDLI"
     gene            complement(14167..14316)
                     /locus_tag="VQU19_000015"
     CDS             complement(14167..14316)
                     /locus_tag="VQU19_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HET2479350.1"
                     /translation="MDKVETTIKSLCVHHYNLKFYVFNDDLPREWFQLMEKRLETLNS
                     EIVNV"
     gene            complement(14628..16172)
                     /locus_tag="VQU19_000016"
     CDS             complement(14628..16172)
                     /locus_tag="VQU19_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HET2479351.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLEIFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVINAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMNPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            16385..16687
                     /gene="gatC"
                     /locus_tag="VQU19_000017"
     CDS             16385..16687
                     /gene="gatC"
                     /locus_tag="VQU19_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HET2479352.1"
                     /translation="MKITQEEVTHVANLSKLRFSEEETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEQDNYYIKVPAILDDGGDA"
     gene            16687..18153
                     /gene="gatA"
                     /locus_tag="VQU19_000018"
     CDS             16687..18153
                     /gene="gatA"
                     /locus_tag="VQU19_000018"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HET2479353.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDANNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDTKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGIDPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            18153..19595
                     /gene="gatB"
                     /locus_tag="VQU19_000019"
     CDS             18153..19595
                     /gene="gatB"
                     /locus_tag="VQU19_000019"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HET2479354.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDLHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVELEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKATILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMIAIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            19724..20284
                     /gene="efp"
                     /locus_tag="VQU19_000020"
     CDS             19724..20284
                     /gene="efp"
                     /locus_tag="VQU19_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HET2479355.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            20306..20695
                     /locus_tag="VQU19_000021"
     CDS             20306..20695
                     /locus_tag="VQU19_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET2479356.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGVYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            20688..21110
                     /gene="nusB"
                     /locus_tag="VQU19_000022"
     CDS             20688..21110
                     /gene="nusB"
                     /locus_tag="VQU19_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HET2479357.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTNVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKVGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(21159..21536)
                     /locus_tag="VQU19_000023"
     CDS             complement(21159..21536)
                     /locus_tag="VQU19_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2479358.1"
                     /translation="MVLSNGQPTFLSTILSFVLLVIIGPVFEETLDRGYFMNTFFPKS
                     KYYLDVILSGLIFGISHLILSHRDPISLLYYSLIGFFFALVYRSTDNLRLTILCHSFF
                     NFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(21877..22062)
                     /gene="briC"
                     /locus_tag="VQU19_000024"
     CDS             complement(21877..22062)
                     /gene="briC"
                     /locus_tag="VQU19_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HET2479359.1"
                     /translation="MTGTETFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRTG"
     gene            complement(22221..22988)
                     /locus_tag="VQU19_000025"
     CDS             complement(22221..22988)
                     /locus_tag="VQU19_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HET2479360.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEVGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(22985..23851)
                     /locus_tag="VQU19_000026"
     CDS             complement(22985..23851)
                     /locus_tag="VQU19_000026"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HET2479361.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(23888..25255)
                     /gene="accC"
                     /locus_tag="VQU19_000027"
     CDS             complement(23888..25255)
                     /gene="accC"
                     /locus_tag="VQU19_000027"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HET2479362.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(25267..25689)
                     /gene="fabZ"
                     /locus_tag="VQU19_000028"
     CDS             complement(25267..25689)
                     /gene="fabZ"
                     /locus_tag="VQU19_000028"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HET2479363.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGTLTFAIGN"
     gene            complement(25686..26171)
                     /locus_tag="VQU19_000029"
     CDS             complement(25686..26171)
                     /locus_tag="VQU19_000029"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HET2479364.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVASEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(26174..27409)
                     /gene="fabF"
                     /locus_tag="VQU19_000030"
     CDS             complement(26174..27409)
                     /gene="fabF"
                     /locus_tag="VQU19_000030"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HET2479365.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(27431..28162)
                     /gene="fabG"
                     /locus_tag="VQU19_000031"
     CDS             complement(27431..28162)
                     /gene="fabG"
                     /locus_tag="VQU19_000031"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HET2479366.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVIAIDGGLSM"
     gene            complement(28196..29116)
                     /gene="fabD"
                     /locus_tag="VQU19_000032"
     CDS             complement(28196..29116)
                     /gene="fabD"
                     /locus_tag="VQU19_000032"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HET2479367.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(29109..30083)
                     /gene="fabK"
                     /locus_tag="VQU19_000033"
     CDS             complement(29109..30083)
                     /gene="fabK"
                     /locus_tag="VQU19_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HET2479368.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     ISIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVE
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWAGVVRND"
     gene            complement(30202..30426)
                     /locus_tag="VQU19_000034"
     CDS             complement(30202..30426)
                     /locus_tag="VQU19_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HET2479369.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(30486..31460)
                     /locus_tag="VQU19_000035"
     CDS             complement(30486..31460)
                     /locus_tag="VQU19_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HET2479370.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGEELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANNRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(31460..31894)
                     /locus_tag="VQU19_000036"
     CDS             complement(31460..31894)
                     /locus_tag="VQU19_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET2479371.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(31988..32773)
                     /locus_tag="VQU19_000037"
     CDS             complement(31988..32773)
                     /locus_tag="VQU19_000037"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HET2479372.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            33098..34462
                     /locus_tag="VQU19_000038"
     CDS             33098..34462
                     /locus_tag="VQU19_000038"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HET2479373.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            34465..34836
                     /locus_tag="VQU19_000039"
     CDS             34465..34836
                     /locus_tag="VQU19_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HET2479374.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKISRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            35050..36324
                     /gene="serS"
                     /locus_tag="VQU19_000040"
     CDS             35050..36324
                     /gene="serS"
                     /locus_tag="VQU19_000040"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HET2479375.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGTDEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(36349..37248)
                     /locus_tag="VQU19_000041"
     CDS             complement(36349..37248)
                     /locus_tag="VQU19_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HET2479376.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACSGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPALSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(37358..37906)
                     /locus_tag="VQU19_000042"
     CDS             complement(37358..37906)
                     /locus_tag="VQU19_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HET2479377.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(38124..39446)
                     /locus_tag="VQU19_000043"
     CDS             complement(38124..39446)
                     /locus_tag="VQU19_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HET2479378.1"
                     /translation="MLELLKSIDAFAWGPPLLILLVGTGIYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSITESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMALIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGARFIWLYRVFFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFDK"
     regulatory      complement(39537..39625)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(39789..42125)
                     /locus_tag="VQU19_000044"
     CDS             complement(39789..42125)
                     /locus_tag="VQU19_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HET2479379.1"
                     /translation="MNKKILETLEFDKVKALFDPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVHFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(42229..42777)
                     /locus_tag="VQU19_000045"
     CDS             complement(42229..42777)
                     /locus_tag="VQU19_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HET2479380.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIFYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(42774..43076)
                     /gene="zapA"
                     /locus_tag="VQU19_000046"
     CDS             complement(42774..43076)
                     /gene="zapA"
                     /locus_tag="VQU19_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HET2479381.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            43163..44044
                     /locus_tag="VQU19_000047"
     CDS             43163..44044
                     /locus_tag="VQU19_000047"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HET2479382.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQLVEENRGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TSDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQEANRFSNPISLEEKAEG
                     KYLSVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLSFC
                     AKLHFKNTEKAKKRLER"
     gene            44048..44662
                     /gene="lepB"
                     /locus_tag="VQU19_000048"
     CDS             44048..44662
                     /gene="lepB"
                     /locus_tag="VQU19_000048"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HET2479383.1"
                     /translation="MNSFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            44941..47307
                     /locus_tag="VQU19_000049"
     CDS             44941..47307
                     /locus_tag="VQU19_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HET2479384.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLSKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLVRILEKGKQKSHDLETIQKHITTIEEELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDFRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTHLEKIYRQSKESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGAALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKGDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDSIPAMIGITDTDLKEIFGK"
     gene            complement(47355..48638)
                     /locus_tag="VQU19_000050"
     CDS             complement(47355..48638)
                     /locus_tag="VQU19_000050"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HET2479385.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     EDGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(48832..49191)
                     /locus_tag="VQU19_000051"
     CDS             complement(48832..49191)
                     /locus_tag="VQU19_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET2479386.1"
                     /translation="MDSPKSLASYRVIGISDRVLEILKEYLLLEEGDYIFTNNGSPLM
                     ITCFNYFLKNRFRKSEIKKDDFVLTAHVFRYSHISLLAELEVPITAIMDRVDYTNETK
                     ILSVYTHVTEKMKSNIT"
     gene            complement(49490..50119)
                     /locus_tag="VQU19_000052"
     CDS             complement(49490..50119)
                     /locus_tag="VQU19_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HET2479387.1"
                     /translation="MVLSKYYGVADGMNVEGRGSANFIKDNVLITAAHNYYRHDYGKE
                     ADDIYVLPTVSPSQEPFGKIKVKEVRYLKEFRNLNSKDAREYDLALLILEEPIGAKLG
                     TLGLPTSQKNLTGITVTITGYPSYNFKVHQMYTDKKQVLSDDGMFLDYQVDTLEGSSG
                     STVYDASHRVVGVHTLGDGANQINSAVKLNERNLPFIYSVLKGYSLEGW"
     gene            complement(50164..50403)
                     /locus_tag="VQU19_000053"
     CDS             complement(50164..50403)
                     /locus_tag="VQU19_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2479388.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPGSNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            complement(50553..50819)
                     /locus_tag="VQU19_000054"
                     /pseudo
     CDS             complement(50553..50819)
                     /locus_tag="VQU19_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060522.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(50844..51152)
                     /locus_tag="VQU19_000055"
     CDS             complement(50844..51152)
                     /locus_tag="VQU19_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HET2479389.1"
                     /translation="MDWDFADTCWEKEPRKYQYVAANYLKAMQSYLKETDLPKLEQLV
                     VTKSWWDTVDILDRVVGSLVYEHPELEEIILILFENLFKPRQLYLQPQNSVLRLQIAS
                     "
     gene            complement(51077..51319)
                     /locus_tag="VQU19_000056"
     CDS             complement(51077..51319)
                     /locus_tag="VQU19_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HET2479390.1"
                     /translation="MSLADLLEELEAAKDSKKARPMEAYMRHQFSFLGIAVPERNKLY
                     KNIYQKRKKQRLSIGILQTLAGKRSLENTNMWLLTI"
     gene            complement(51320..51952)
                     /locus_tag="VQU19_000057"
     CDS             complement(51320..51952)
                     /locus_tag="VQU19_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2479391.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF"
     gene            complement(51966..52961)
                     /locus_tag="VQU19_000058"
     CDS             complement(51966..52961)
                     /locus_tag="VQU19_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET2479392.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLYDVEKTEK
                     FVFLLLVFSMSMTCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVVDPDLDASFKS
                     LSGKLNLLTEALQKAENHSLDQEEEIIEKERKRIARDLHDTVSQELFAAHIILSGISQ
                     QALKLDREKMQTQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFRLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            complement(52958..53656)
                     /locus_tag="VQU19_000059"
     CDS             complement(52958..53656)
                     /locus_tag="VQU19_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HET2479393.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            complement(53734..54744)
                     /locus_tag="VQU19_000060"
     CDS             complement(53734..54744)
                     /locus_tag="VQU19_000060"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HET2479394.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSKQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKAVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEAKDQMK
                     KA"
     gene            complement(54728..55735)
                     /locus_tag="VQU19_000061"
     CDS             complement(54728..55735)
                     /locus_tag="VQU19_000061"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HET2479395.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLTPNPDYSLIQETIALMGDFLAVRGQNLRSFSLEICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYDVSVDQELLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKVAAWLEEENLATVLERDWGFSISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLSSSKETVVSLVEALEQGKSEKIIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTKTLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            complement(55722..56675)
                     /gene="mvaD"
                     /locus_tag="VQU19_000062"
     CDS             complement(55722..56675)
                     /gene="mvaD"
                     /locus_tag="VQU19_000062"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HET2479396.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVIADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YSVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGQRYRLIVSKTKDLSQDDCC"
     gene            complement(56657..57535)
                     /gene="mvk"
                     /locus_tag="VQU19_000063"
     CDS             complement(56657..57535)
                     /gene="mvk"
                     /locus_tag="VQU19_000063"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HET2479397.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLDITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            complement(57657..57986)
                     /locus_tag="VQU19_000064"
     CDS             complement(57657..57986)
                     /locus_tag="VQU19_000064"
                     /inference="COORDINATES: protein motif:HMM:NF024736.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2479398.1"
                     /translation="MTRKAYDTDLNDQEWAKIEPYFSKHRTYKWPKRVLVNETLYVTK
                     TGCQWRMIPHDFPLYLTVWSFFRRSMTTGWFQVNGRWYYAYSSGALAVNTTVDGYSVN
                     YNGEWVQ"
     gene            58648..58984
                     /locus_tag="VQU19_000065"
                     /pseudo
     CDS             58648..58984
                     /locus_tag="VQU19_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811282.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic-modifying protein"
     gene            58884..59471
                     /locus_tag="VQU19_000066"
     CDS             58884..59471
                     /locus_tag="VQU19_000066"
                     /inference="COORDINATES: protein motif:HMM:NF017000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2479399.1"
                     /translation="MTILLKLSSTIVYGEIYHYFLQRDTAKESILDYSFAHGYCEIAY
                     ALFAYSKVLEPSMFYNDLHTFHAELKKLLEKVTSNTENLGNLQLSWCEGISGIILYLC
                     MYDCDGNKDIISKYQEFVFNHHLKMMTGYCHGITSLLQTTVYNQNKLLMKKIQQVILA
                     CSERDDHGLLMFQGDSGKADLFDFGIGSRGYIGVY"
     gene            59514..60746
                     /locus_tag="VQU19_000067"
     CDS             59514..60746
                     /locus_tag="VQU19_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET2479400.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEMVPLLSQLFLGILGDFQENRVKHALCIAKIKILLYAILTVFLVLSPFSLV
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVHIVANLAGA
                     FLINVISIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLRLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLFALLSIIMS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLALITSILCQAYIVIFVTSFISSTIIGI
                     LSPRLQAAVFAHIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLALIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(60864..61820)
                     /gene="cbpC"
                     /locus_tag="VQU19_000068"
     CDS             complement(60864..61820)
                     /gene="cbpC"
                     /locus_tag="VQU19_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HET2479401.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDDLFDNRPVFEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     DGNWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLRSSGAMA
                     TGWYQEGTTWYYLDQPNGDMKTGWQNLGNKWYYLRSSGAMATGWYQDGSTWYYLNAGN
                     GDMKTGWFQVNGNWYYAYSSGALAVNTTVDGYSVNYNGEWVR"
     gene            complement(61918..62607)
                     /locus_tag="VQU19_000069"
     CDS             complement(61918..62607)
                     /locus_tag="VQU19_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2479402.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            complement(62619..64043)
                     /gene="gndA"
                     /locus_tag="VQU19_000070"
     CDS             complement(62619..64043)
                     /gene="gndA"
                     /locus_tag="VQU19_000070"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HET2479403.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVSDVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEDQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            complement(64119..65513)
                     /gene="mapZ"
                     /locus_tag="VQU19_000071"
     CDS             complement(64119..65513)
                     /gene="mapZ"
                     /locus_tag="VQU19_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HET2479404.1"
                     /translation="MSKKRRNRHKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTNSN
                     KTALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLVTQIKAIQDVNAQFEKPAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            complement(65526..66683)
                     /locus_tag="VQU19_000072"
     CDS             complement(65526..66683)
                     /locus_tag="VQU19_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HET2479405.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARLPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVERKLELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            complement(66768..67148)
                     /gene="rnpB"
                     /locus_tag="VQU19_000073"
     ncRNA           complement(66768..67148)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VQU19_000073"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            complement(67169..67498)
                     /gene="gpsB"
                     /locus_tag="VQU19_000074"
     CDS             complement(67169..67498)
                     /gene="gpsB"
                     /locus_tag="VQU19_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HET2479406.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            complement(67568..68095)
                     /locus_tag="VQU19_000075"
     CDS             complement(67568..68095)
                     /locus_tag="VQU19_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HET2479407.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            68161..68757
                     /gene="recU"
                     /locus_tag="VQU19_000076"
     CDS             68161..68757
                     /gene="recU"
                     /locus_tag="VQU19_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HET2479408.1"
                     /translation="MINYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            68754..70913
                     /locus_tag="VQU19_000077"
     CDS             68754..70913
                     /locus_tag="VQU19_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 1A"
                     /protein_id="HET2479409.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGIYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLTYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWSSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(71080..76383)
                     /locus_tag="VQU19_000078"
     CDS             complement(71080..76383)
                     /locus_tag="VQU19_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK signal domain/LPXTG anchor domain surface
                     protein"
                     /protein_id="HET2479410.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATANENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWQTVEKKEQQGTVTIREEKGVRYNQLFSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKEDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKTPGNSTWYKGNRVVAPEPGSVNRLSITLKSDGQLNASNNDVNLFDTVTLPGAVN
                     DNLKNEKKILLKAGTYGNDRTVVSVKTDNQEGVKADDTPAQKETGPVVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYSLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPSAKVVITEDANADKKVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVFLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTDKEKMYYFNTQAGATTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRNNATVNDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDQAT
                     YFDEIRTFENNSSMYGDKHDTGQGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HDPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKATFLVTGAETGD
                     TWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTALVADD
                     FASLTAPAQAQEGLANAFDGNLSSLWHTSWNGGDVGKPATMVLKEPTEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALAKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLSSLVSDQGKTPDYKQEIA
                     RPETPEQILPATGESQSDTALFLASVSLALSALFVVKTKKD"
     gene            complement(76684..78666)
                     /locus_tag="VQU19_000079"
     CDS             complement(76684..78666)
                     /locus_tag="VQU19_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2479411.1"
                     /translation="MKSSKLLALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDDQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHVDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQGSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNIFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVIIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDEATDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPVLYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
BASE COUNT        22982 a        17986 c        14610 g        23413 t
ORIGIN      
        1 ttctatcttc cattatatca tactttttca gtctatggta gctctcttta aaaggcaccg
       61 atactgccgc cacctccgcc tccagagaag ccaccaccag aacttccact tccagaagat
      121 acagagtagg tgcttgctgt atttgcgaca ctagcataat ggctcatttg cgcgcttgaa
      181 tgataaaaca gactgtgcca gccataagct acatagagat tgatatctgg attttccact
      241 tgaatctgat gaaccttcat caaatgacta accttgtccg catagccaaa taaggtcgca
      301 tagaccaaga ggcgattcca gaccacaata ctttccagtt cagcctgatc caatcgtgca
      361 atctcacgca acatattttc aaaactggtc cagagatagt agacctcagc tcccgcttca
      421 tttagaacac catcacgatt atctagtcga agcttccaat aatagaaaac agacaaaact
      481 aaccctagaa aaccaagtat tggcaaaggg aggtaaagat agccatgaac gtctaaactg
      541 tacaagaaca aaccaaatcc gataaatagg ggcaggatag tcaaggcacc catacccact
      601 tgcaaggcct tttccccacc agttaaagga cgataataat ctgggagccc ccagaaggaa
      661 actcgttttc tcactccttc ttgcatctgg ttcaatacct cttcaaaaga agatttgagt
      721 tgaagccctc ttgcttgaat ccgtttttca tcagaaactt tggctctacg ataaagacta
      781 tcagatacct tgtaatccgc aaacaaattg gaaagagttt cttctttttt acctgaaaaa
      841 gctagattta ggcagtcttt ctcaaagctt gacaaaccat cttcttttac tagcctcaaa
      901 ccaactgcat ctccttctga aatgatagag acattcccac ggtctatcac atctagcaag
      961 gtagcttgaa taagttgatc aaaggtgaat tttccagctc ccttgaccaa gggactcact
     1021 tcctccaagg aggtcgagta gactgcttct gataaaacca taggctctaa ttccattggt
     1081 ggttcataga gacgatgatt tttggcatat ttgactgaag gagtggtctt tcttctataa
     1141 ataaaataga agcagacact caataacaag gagatagaaa ggatcgaagg gaggacccaa
     1201 gtaacaagtt gtttactctg atctttttct ctaacaatcg agtcttctat cttattaaac
     1261 tcttctaaac gattcccttt caatccctga tccctagcgc tagcaaaatc ggtccgaggc
     1321 caataggcat gcaactcaac tccacgctta gccggaagat tgtctaaacg gatagtataa
     1381 tcaaggttac tcttttcaat cgttccctct ctaaaaagtt tccctgtatg gaaaaagagt
     1441 ttttcagctc ccttgtctcc ccttacatga aattcaaact tttcaataga ctctgaacta
     1501 tctgtcagag gttgccaatt taattcagcg atatcatcat aaaggaaaag taaatttttt
     1561 aagttccaga cgaggtcaac ttcaactatg tcgccctcct gacctggatt atagactctc
     1621 acagtataac catccgcttc ttctgttact tcgctagtca catctgctag ttctgcaccg
     1681 tttttcgcgg cctgaacctt tggatgaggg tcaatgtcaa acccgctagg catcttacca
     1741 gcacgtccaa gtcccacgat ttgtccctta aagtcctcct caaactggta aactatcttc
     1801 tgtctaaact ctgccgtatt atctgcatga atatacaaat ccccttgata agagtttatc
     1861 ttgaaatcaa tggcaaaaac agagagtgga agaaggcaaa acaagcctaa caccagtaag
     1921 aaaaaagttt ttttcatcaa ctaagccccc tttttatctt tcttatcatt atagcatttt
     1981 ttcgtaagta aaggcttact tatgttgaaa aattacgcat ttttcgataa aataggagac
     2041 agttattttt taatagatca gaataggaga aatcatgaga aaaatatact tatctatttt
     2101 cacaagtctc ttgctgatgc taggacttgt caatgttgct caagccgatg aatatttacg
     2161 catcgggatg gaagcagcat atgctccctt taactggacc caggatgatg atagcaacgg
     2221 agctgtcaaa atcgatggga ccaatcagta tgccaacgga tacgatgttc aaatcgccaa
     2281 gaaaatcgct aaggacttag gtaaaaaacc tttggttgtt aaaaccaagt gggaaggtct
     2341 agtccctgcc cttacttctg gtaagattga catgattatc gcaggtatga gtccaactgc
     2401 agaacgcaaa caagaaattg ccttttcgag cagttactac actagcgaac cagttttgct
     2461 tgtcaaaaaa gattctgcct acgcaagtgc taaatctttg gatgacttta acggtgcaaa
     2521 aatcacttct caacaagggg tctacctcta cgacttgatt gcacaaatcc caggtgctaa
     2581 aaaagaaaca gccatgggag acttcgctca aatgcgacaa gctcttgagg ctggtgtcat
     2641 tgatgcttat gtttctgaac gtccagaagc actgactgct gaagctgcga actctaagtt
     2701 caagatgatt caagtagaac ctggtttcaa aactggggaa gaagatacag ctatcgctat
     2761 cgggcttcgt aaaaatgaca atcgtattag ccaaatcaat gccagcattg aaaccatttc
     2821 aaaagatgac caagttgcct tgatggatcg tatgatcaag gaacaacctg ccgaagctac
     2881 aacaactgaa gagactagca gtagtttctt tagccaagtc gctaaaattc tttctgaaaa
     2941 ctggcaacaa ctcttgcgtg gtgctggtat cactctttta atctctatcg tcggaaccat
     3001 cataggtctc attattggac ttgccattgg tgtcttccgt actgctcctc tctctgaaaa
     3061 caaagccatt tatggccttc aaaaactagt cggctgggtt ctcaatgtct acattgaaat
     3121 tttccgtggt acgccaatga ttgttcaatc gatggttatc tactatggaa ctgcccaagc
     3181 tttcggtatc aaccttgacc gtacactagc tgctatcttc atcgtttcaa tcaataccgg
     3241 tgcctacatg actgaaattg tccgtggtgg tatcctggca gttgacaagg gacaatttga
     3301 agctgcgact gctcttggta tgactcataa ccaaaccatg tgtaagattg tcctacctca
     3361 ggttgtccgc aatatcctac cagcaactgg taatgaattt gtcatcaata tcaaagatac
     3421 atctgtattg aacgttatct ctgttgtcga actttatttc tcaggaaata ccgtggcaac
     3481 acaaacctat caatacttcc agacatttac aatcatcgcc gtgatttact ttgtcctcac
     3541 cttcaccgta acacgtatcc tacgctttat cgagcgcaga atggacatgg atacctacac
     3601 tacaggtgct aaccaaatgc aaacggagga tttgaaataa tgacacaagc aatccttgaa
     3661 attaaacacc tcaaaaaatc ctatggacaa aacgaagtgc taaaagacat ttctctcact
     3721 gtccacaagg gagaagttat ttctatcatc ggaagctctg gaagtgggaa atcaaccttc
     3781 ctacgctcca ttaacctact tgaaacgcca actgatggac aaatccttta tcatggacaa
     3841 aacgtcctcg aaaaaggcta tgacctcacg caataccgtg aaaagttagg gatggttttc
     3901 caatccttta acctctttga aaatctcaac gttcttgaaa acacaatcgt cgctcagaca
     3961 actgtcctta aacgcgaacg cacagaagct gaagaaattg ccaaagaaaa cctggaaaag
     4021 gtcggcatgg gagaacgcta ctggcaagcg agacccaaac aactctcagg tggtcaaaaa
     4081 caacgtgtgg ccatcgctcg tgccctttca atgaatcctg acgccattct ctttgatgaa
     4141 ccaacatcag ctctcgatcc agaaatggtt ggagaggtcc tcaaaatcat gcaagatctg
     4201 gctcaggaag gcttgaccat gattgtcgta acccatgaaa tggaatttgc ccgtgatgtc
     4261 tctcaccgtg ttatctttat ggataagggt gtgattgctg aagaaggtaa accagaagac
     4321 ctcttcacta atcctaaaga agaccgtaca aaagaatttc ttcaacgtta tctcatactc
     4381 aatgaaaatc aaagagcaaa ctaggcagct agccgcaggt tgctcaaaac actgttttga
     4441 ggttgcagat agagctgacg tggtttgaag agattttcga agagtatcaa ataaaaagaa
     4501 aaggctgcat caaccgtgca gtctttttgc tgtcctcaaa atgaaaaggc agattctcta
     4561 tctctactac ttgaaggtca agaatccacc gttatccaaa gattaatctt caaatttttc
     4621 atgatttttt tcatagaaat caattaagcc tagggctgtt tcaaatgaaa tattttttac
     4681 ttttgcacga ccctgcgcca gagcaatgat agacatttca cgcgcattcg tttctttaga
     4741 gatacggtag cctgtgattt tcttatcacg aacccagcca acaactgatt ctactttttc
     4801 aaagtttgac ttagccatgt ttttctccta ttttcttctt tataatattt aattgtatac
     4861 gtttttacta cttttgtcaa taaaaaaaac atatattcaa cgaaaataat tagttcagaa
     4921 ttttcttact tcctttttaa atccgataat atataggttt tgctagcctc tacaccataa
     4981 atatttgcta ataaaaatac tgtattatta ccctcttaag gtgcaaaatt attcaagttc
     5041 ttaaaaaatg cttctctatt tccgtaagat agcttatttc ttcgatttaa gaactgaaga
     5101 tgatagttct aacctttaga aatccaagcc ttctctagct caaaaactcc tatctttctt
     5161 cctcaataaa tcatctgaga gataggtatt ccttatatcc ttcaaattca tcactccttt
     5221 ggatattgag gtgctagcct agaagcagac acccgattat ctaaaccatc cttaatagag
     5281 atgacaagac agataagctc agttaattac ttatatatct ttttaatatg gtatatttgt
     5341 caacaaaaag aaatcaaatc ataccttata ctcaatgaaa atcaaagagc aaactaggaa
     5401 gctagccgca aattgctcaa aacactgttt tgaggtttca gatagagcta acgtggtttg
     5461 aagagatttt cgaagagtat taaagacagt atgactatgc ttgtcaatag ataggaaatc
     5521 aaaatgaagg atggaaatct gagccaaaca tcataagtgc tataatgaac agaagtaaga
     5581 attgcacgat aagttttcta aaaccatagg aatcgtcccc tttcttcatc ttcattatag
     5641 cacatataca tcagttgtac aaataatatg atattttttt attagtcctc agacaagcat
     5701 attataaagc gtttcattac catttaagtt aatataagct ggatcaaaac cttccattct
     5761 acggatcaaa cctgcataat catgcttatc tgccaaagcg atcccaatca atactgggcc
     5821 tgttcccttg ctagctcgtt tgatatactc aaaacgtgtg atatcatcat ttggccccag
     5881 gatatcattt acaaactcac gcaaagctcc tggacgctgt gggaaattga ccacaaagta
     5941 atgtttgata ccatcataaa tcaaggcacg ctcttccatt tctggcatac ggttgatatc
     6001 attatttcct ccagaaatga tacaacaaat ggttttcccc ttaatatatt cagctaaaac
     6061 ctctaaagag gcgatactag ccgctccagc aggttctgcg actatccctt gcttagagta
     6121 aaggtcaatc aaggtttcag aaatcaatcc ctcatcgaca cctaccaaag tttgaatatg
     6181 ttgacgagtt gcttcatagg tcaactgacc taccttttgc acagcaatcc catccgcaaa
     6241 tttatcaatt tccttgagtt tgactggacc tccagcctca aaggcagctt tcatggaacg
     6301 cgctccattc gcctctactc cgataacctc aatctctgga cttgtttcct tgatataggt
     6361 agaaaccccg gcaatgagac cgccaccacc aacaggaacc aagacagcat caaaatcaat
     6421 cgattctttt cgagcttctt ctaaaatctc ataagcaact gttccttgac ctgcttgaac
     6481 atgagcatca tcaaaaggat caataaaggt acgattttca gagactgtaa attcttgagc
     6541 tgctttggct gaggcatcaa aggtatctcc aactagttta atagttacaa aatccccacc
     6601 aaaaaagcga acctgaccaa tcttttgttg tggcgtagta ataggcataa agatagtagc
     6661 aggaattttc atttcattac aagtataggc tactccctgc gcatgatttc ccgcagaagc
     6721 gcagactacc ccacgttcac gttcttcctt gctgagctgg gaaatggcat aataggcacc
     6781 acgaatttta aaggagcgaa cacgctgggc attttctttt ttcaaataaa tcttagcacc
     6841 atacttctcc gataaataat gatcgtaatc cagtggagta ttcacaacca caccgttcaa
     6901 gaccttgtga gccttgatta tatcttttga acttaacata taaaacctct ttttctataa
     6961 aaaacagtca ctaatgactg ttttttagtt attcatctcc gaaaacttca gtaacacttt
     7021 catggtattt atgagccata cgaatcgaaa actctttagg aagttcataa cgatttgtgg
     7081 aaatccaatc atataaccat tctaccaaac tttcttcact atcattacga tggaagataa
     7141 aatagtttaa aatttcttta tattctacat cattcaaatc caacgtgtct acaaattgac
     7201 tacgaggaac aaaattagaa tctaattttc ttagttgatc tgtcaattct cccaattgta
     7261 aatccaactg aaaaaatagt ttttgcagtt gcctatcagt ttcatcacat cctgtcttga
     7321 tagaaaacaa attggtaata ttcatatgat ttcaacccct aaataagtac atctaatatc
     7381 ccacgaatag ctgaagctaa agttttcgca gtccagtcat ttaaacccga ttctttcaat
     7441 ccagatgcaa taatttgctc tatttgatat aaaccgccat ctatcgtctc atttattctg
     7501 cgaagaggac cttcaatata ggataaagct tctccgaatc taacagctga tttaggtcct
     7561 aatgatttac caactatatt tgttaatgtt ttttatttct caaaatccat ttcgctatat
     7621 aacgagcaga tttagtcgca ccagctctct caaacggaga atgaatttca agaccttctt
     7681 ctctagctat ttgtgccaat ttgaagaatt gttcaaaggt catatgcaac ctaccatctt
     7741 caaaattagc atcatcataa atgttaatta cagcattttc atcatacgac caatctgctt
     7801 tattttggtc tgctagcact attaccgacg gtgtaattac attatacaac tagaaccaat
     7861 aataacgatg caatttttct cataatcttt ttcataaaat catctccagc gctatatatt
     7921 tctaattagt tatagatttt gaatgcatca tcgtcgtttt taccaacaaa tggcattgct
     7981 ttacgcaatt ctgcaccaac tttttcaatt tcaaggttag ctgcttgttc acggtaagca
     8041 gtcaattttg gacgtccagc tttatagtca tttacaaagt catttgcaaa tttaccattt
     8101 tggatgtctg ccaagacagc cttcatattt tctttaactt gttcagtgat tacacgtgga
     8161 cctgatacat agtcaccgta ttcagcagtg tttgaaatag attgacgcat tttcttgaat
     8221 ccaccttcgt agatcaagtc aacgatcaat ttcatttcgt gaagaacttc aaagtaagcc
     8281 aattctggag cgtaacctgc ttctgtcaag acttcgaaac ctgcttcgat aagggcagtc
     8341 aaaccaccac aaagtacagc ttgttcacca aacaaatctt cttcagtttc ttctttgtaa
     8401 gttgtttcaa gaagacctac acgagccgct ccaacacctt tacaccagtc catagcaatg
     8461 tttttagcat ttcctgttgc atcttggtat actgcataaa gagctggaac accaaatcct
     8521 tcttcgtaag tacgacgtac caagtgtccc ggtcctttag gagcacacat gaagacatct
     8581 acatccgcag gaactttgat aaattcaaag tggatgttga aaccatgggc aaatccaact
     8641 gcgtttccag cttccaagtt tggagcgatt tctgcttcgt acaattcttg ttgaatttcg
     8701 tctggcgcca agatcatgat aacatcagcc aacttagtag cttctactac tgtgtaagta
     8761 tcaaatccat cttcttttgc tttatcaaaa gatttacctg gacgtacacc gataataacg
     8821 tcacgacctg aatcacgcaa gttttgagca tgcgcatgtc cttgtgaacc ataaccgata
     8881 acggcgattt ttttaccgtc aagtgctgct actttaacat ctttttcata ttccatttga
     8941 actgtcatag cttttctctc ttttctatta tttattgcct tttaggctgg tttaataaat
     9001 ttaagttgga tttttaatcg cgggtaaatc cagttgcacc cgttcgagca atattgcgaa
     9061 taccgtatgg gcgaatgact cgcaataggg cttcgctctt ttctgcattt cccgtcatct
     9121 gaatggtaat cgagcttggc gctacgtcta ccactgttgc acggaaaggt tgaataatcg
     9181 ctaaaatctc agctctcttc tcagctggcg ctgacatctt aaccaaaatc acctcgcgct
     9241 ccaaatgagg cttgtctgta atatctcgaa tgcgaatcac atcaatctga cgattgagct
     9301 gtttgatgat ttgctccact tcatcatgag aagcaacatc aataataata gtgatacgcg
     9361 atacattcgg atcttctgtt gctccaacag agatgctttc aatattaacc tgacgacgag
     9421 ataggacacc tgtaaagcga ttgaggactc ctgaacgatt ttgtagtttt gctgttaaca
     9481 ttctacgcat ggaactgcac ccccaacatc tcatgattac tcttaccagc cggtaccatt
     9541 ggtaacacct gttccttacg agaaatatct acctcaatta gcataggaac atcctcagtg
     9601 atgacttcaa ggtcttgagc caaggtctca ggattgtcaa acttatagtt tttaatacca
     9661 taagcctgcg ccatcaattg gaaatcagga agggtatcaa agaccgactc tgatgttctg
     9721 ccttcataga aggattcctg ccactggcga accattccaa gtgaatgatt gttcagcata
     9781 accaccttga ttggcacctt gtaaatattc aaaatagcca actcctggtt ggtcatttgg
     9841 aaaccaccat ccccaacaaa caagactact tccttatctg ggttagcaat tttagcaccg
     9901 attgctgctg gaattccaaa gcccattgtt cccaaaccac ctgaagtcac taactgacgc
     9961 tcattttggt agggataata ctgagctgtc cacatttggt gttgaccaac gtctgttacc
    10021 acaatggcat ctccattcgt caattcacca attcgttcaa taactgcttg cggttgaacc
    10081 acacgctctt tcttgtcata agaacgaaca cgattcttgt ctttagtgac tttctcaatc
    10141 cacttttcag tattgttgtg aactgttggt tctgctagca acatttgcaa ggccttctta
    10201 gcatctccaa ctacaggaat gtctgcactg ataatcttgc caatctcagc tgggtcaata
    10261 tcaatgtggg caaccttagc attcttagcg aaagtcttag gattccccgt caaacggtca
    10321 tcgaaacgag aaccaatact aatcataaag tccgcttccg tcatggcaat atttgctgcg
    10381 aatgacccgt gcatgcctcc cattccaaga aagagtgggt gactcgttgc aatcgttcct
    10441 tgtcccaaaa gactggttac cactggaatt tgatagcgtt ctgcaaattc atttagttcc
    10501 gtagcagcct cagcataact aattccacca ccagctaaca agactggctt tttagccttg
    10561 gacaattgct tcaagatttt cttgatttgc atatcattcg gctcaagagt cggctgataa
    10621 cttggtaaat tcacttctgg tgaataaatg aagtctgttt ctaaagcaga tatgtctttt
    10681 ggtaggtcaa ttacaactgg ccctggacgg cctgtagttg cgatatggac agcttccgta
    10741 atgatacgcg gaatatcagc tgtctcacga acttggtaat tgtacttagt gattggcatg
    10801 gtaattccta cgatgtctgc ctcctgaaag gcatccttcc caatccctgc tcgcgccacc
    10861 tgacctgtaa agaccaaaag gggaacgcta tcgctcatag catccgcaat ccctgtaatg
    10921 gcatttgttg ctcctggtcc actagtgacg acggcaacac ccaactttcc agttgatttg
    10981 gcataacctt cagcttcatg caaacaacct tgctcatggc gccctagaat gtggcgaatg
    11041 cctttaaaat tatatatcgc atcataaaaa ggcaaaaccg caccaccagg ataaccaaag
    11101 atggtatcaa ctcctaaatc acgaagtgtt tccaaaacta ggtccgaccc cgtcttagga
    11161 gattctaaac tgattttctc cattgttccc ctttctttcc tcttaaaaat aacttgttac
    11221 tatcatacca ttttttcaaa atttttcaag ataaaagaag aaattttctg aattttctat
    11281 tttaacgttt atttatgaat gttatttttg tttttattaa aaagataccg atttcattta
    11341 ctaaaaaaga aaaaagaact gatttctcag tccttcatta atcttattcc acactaaata
    11401 ggtatgggta aacaggttgt tgaccttggt gaatctcgac ttcaacgtct tcgaattctt
    11461 ctacgatttc ttgagcgatt tcattggcaa gttcttcgct tccgtcttca ccgacataga
    11521 aggttacgat ttcactatct tcatccaaca tatgtttcaa ggtttcagtc aatgtttggt
    11581 gcatatcagg gtttgacaca agaatttttc catccaccat acctagatta tcgttttcat
    11641 ggatttctaa gccatcgatc gttgtatcac gcacggctgt tgtgacgctt ccgctaacga
    11701 catcgctaag agcagctgtc atacgctctt ggttttcttc aatggacttg cttggatcaa
    11761 aggcaagaag acttgtcata ccttgaggaa gagtgcgagc ctctaccact actgctggtt
    11821 gctccaaaac ttctgccgca gattgagctg ccatgaagat gttcttgttg tttggcaaga
    11881 agatgatgtt acgggcattg acctgttcaa cagccttgat aaagtcttct gttgaagggt
    11941 tcatggtttg accgccttcg ataacataat ccacgccttg agaacagaag atatctgcta
    12001 gacctttacc agccaccaca gcaatcaaag catactcttt ttcttcagcc gacttgataa
    12061 cttgagtagc ttctttctca acctgtgctt cgtgttggtt acgcatattg tcaactttta
    12121 ccttgaccaa gctaccatat ttgagacctt cttgcataac aagtcctgga tcttctgtat
    12181 gaacatggac tttgacaatt tcatcatcgt taacaacgag gagagaatcc ccaagctcat
    12241 ccaagtagtt acggaattca tcgtagtcaa aatctttagc ataggttgga ccttgcttaa
    12301 gagctaccat gatttcagta cagtaaccaa acgtgatgtc ctcagtcgct acgtgaccag
    12361 ctacagactt atgatgctct acattgatca tctcactcat gttggcagga gtcgctacaa
    12421 agtcctcaga tgcaatatat tcgccagtaa gggctgaaag gaaaccttcg tagatgaaga
    12481 ccaatccttg accacctgag tccacaacgc caacttcttt caatactgga agcatgtctg
    12541 gtgttttagc tagagctgtt ttagcacctt ccaaggctgc gcgcatgact tcaacagtgt
    12601 catctgtttg ctcagctttt ttcttagcac cgatagcagc tccacgagaa actgtcaaaa
    12661 tcgttccttc aacaggtttc atcactgcct tataggcaac ttccacacct gattggaagg
    12721 ccagagccaa gtcttgacct gttaactcgt ctttatcctt gatagcttgg gaaaatccac
    12781 ggaaaagctg agacgtaatc actcctgagt tcccacgcgc acccatcaaa agccctttgg
    12841 caagaatgct cgctacttct ccaactgtag aagctggctt gtctgcaact tctttagcac
    12901 cattttcaat ggtcattccc atatttgtcc cagtatctcc atctggaact ggaaagacgt
    12961 ttaatgaatt gacatattca gcttgcttat tcaagcgagt tgatgcagcc tgcaccattt
    13021 cttgaaataa gctagtagta atttttgaca cggttattct cctacaactt tgatattttg
    13081 aatgtagaca tttacagtct gagcagtaat tccaagctgg ttttccaagc taaaggcaac
    13141 acgctcttga atgttttttg acacttcact aatctttgtt ccgtagctta acacggtata
    13201 tacatcaact gcaatactgc catcttcggc tgcctttacg acgacacctt tagaataatt
    13261 ttccttacct agcagggctt ggaaattatc tttgagggca tttttactag ccataccgac
    13321 cacaccaaaa atctcagttg ctgctccacc tacgacggtt gcaatcactt catctgttag
    13381 ttcgatttga ccatcttttg tattaatttt tacagtcatc ctttttacct caactagttg
    13441 atactctatt ttatcatatt tcagcccaag tgtaaaagca gaatgatgta tcagcggata
    13501 tttactctat ttttcaaacg atgttatacc cacaataaaa gaaaaaagac cctaaggtct
    13561 cctttgcttt tattattaaa cgcgttcaac tttacctgat ttcaaagcac gagctgaagc
    13621 ccaaactttt ttaggtttac catcgataag aacagtaact ttttgaaggt ttggttttac
    13681 ggcacgtttt gtttggttca tcgcgtgtga acggttgttt cctgatacag tcttacgacc
    13741 tgtaaagtaa catactttag ccattgtgtt ttcctcctat tagatctaat atagcggatg
    13801 tgctagcacc acataccgta ctatgttatc acactttctt gttttttgca agggaattgg
    13861 aagatttttt atttgtgtct taaatcaggt cttgcgtgac attttctgct ctccacatgc
    13921 catcgttgat taacagaaca ccagaattaa aattatgtgt ataaaaatca tctctaactg
    13981 cagctaaggg tatagccgtc aagtccaaat cccacagctc atctatcgat tttcttacaa
    14041 caatatctga atccaaatac agtacacgag actcgcttac atactttgga ataaaatacc
    14101 taaaaaagcc gcatatgaaa gtccctcaaa ggggagacga taacctttca gaatattact
    14161 gtcaatctaa acattcacaa tctcactatt caaagtctct agtctttttt ccatcaattg
    14221 gaaccattct cgcggaaggt catcattaaa aacataaaac ttaagattat aatgatgaac
    14281 acaaagagat tttattgttg tttcaacttt atccatataa gcattatctg cacctaagac
    14341 aatcgctttt ttctcttttt tctcttcttt cactttttat ctcatttctt tttattccca
    14401 tcatatgttt ctacgtaacc attattttcg cctattcgtt cgtaaaacca taccagtgga
    14461 gattttagat gaagtcccat tacggtttac aatttttaca ttacgacacg gagttttaca
    14521 aatcgatttc atttgccaaa cgtagttagt gaggcagtta gctagttcgc caaatagcga
    14581 ctagcgtcca acaatttgga actttagttc caattgttgg tactgagtca catcttctcc
    14641 tctaactcta cgtctggata cttgtcagca aaccagcgga gggcaaagtc attttcaaag
    14701 agaaagactg gttggtcaaa acggtctttg gctaagatat tgcgacttga cgacatccgt
    14761 tcatccaagt cctcaggctt gatccaacga acggtctttt tacccattgg gttcataact
    14821 acttctgcat tgtactcgcc ttccatgcgg tgtttaaaga cttcaaactg gagttgacct
    14881 acagcgccta gcatgtactc acctgtttgg taattcttat aaagctgaac ggctccttct
    14941 tgcaccaatt gctcaatccc cttgtggaag gatttttgct tcataacatt cttagcagaa
    15001 actttcatga aaatttcagg agtaaaggtt ggcagtggtt caaattcaaa cttgttttta
    15061 ccaactgtca aggtatcccc aacttgataa gtaccggtat cgtaaacccc gataatatca
    15121 cctgccacgg cattgatcac attctcacga ctttccgcca taaactgggt aacattagat
    15181 agtttggccc ccttaccagt acgagggaga ttgacactca tgccacgctc aaattcgcct
    15241 gatacgatac ggacaaaggc aatacggtca cggtgacgag gatccatgtt ggcttggatt
    15301 ttaaagacaa agcctgagaa atccttgtca taaggatcca caatttcacc gtctgttttc
    15361 ttgtgaccat gtggttctgg agcaaacttg aggaagattt caaggaaggt ctgcacacca
    15421 aagtttgtca gggctgaacc gaaaaagaca ggcgtcaatt ctccagccag aatagcttcc
    15481 tctgaaaact cattcccagc ttcatttaaa agctcaatgt catccttgac ttgctcgtag
    15541 aaaggattgc taccaaagag tttgtccccg tcttctagac tggcaaaacg ctcatcccct
    15601 ttgtaaagct ctaaacgttg gttatagagg tcatacaagc cctcaaaggc tttccccatc
    15661 ccgataggcc agttcatagg gtagctagca atgcccaaga tttcttccaa ttcttgcaag
    15721 agatccaaag gctcacgacc gtcacggtcc agcttgttca taaaggtaaa aactggaatg
    15781 ccacgatgtt tcacaacctc aaacaatttc ttggtttgag cctcgatccc cttggcagag
    15841 tccacgacca tgaccgcagc atccaccgcc atcaaggtac gataggtatc ttctgagaag
    15901 tcctcgtgcc ctggcgtgtc taagatattc acgcgcttgc cgtcgtagtc aaattgcata
    15961 acagatgaag taacagaaat cccacgttgc ttctcgatat ccatccagtc agatttagca
    16021 aaagtccctg ttttcttccc ttttaccgta ccagcctcac gaatctcacc cccaaagtag
    16081 agtaactgct cagtgatggt tgttttcccc gcgtccgggt gggagataat ggcaaaggta
    16141 cgacgtttct taatttcttc ttgaatattc ataagttctc tttctttgat tctctatttt
    16201 tcttgtttca atagctgaga atgattttta cattggattt taccattcct ttcaacattc
    16261 cattatatcg gattttagca tttttttcaa tttctatttc ttttcacttc cccctccctt
    16321 atttatagga aaatatggta aaatagaaca gactaaaaat catcatttca cgaaaggatg
    16381 caagatgaaa attacgcaag aagaggtaac acacgttgcc aatctttcaa aattaagatt
    16441 ctctgaagaa gaaactgctg cctttgcgac caccttgtct aagattgttg acatggttga
    16501 attgctgggc gaagttgaca caactggtgt cgcacctact acgactatgg ctgaccgcaa
    16561 gactgtactc cgccctgatg tggccgaaga aggaacagac cgtgatcgct tgtttaaaaa
    16621 cgtacctgaa caagacaact actatatcaa ggtgccagct atcctagacg atggaggaga
    16681 tgcctaatga cttttaacaa taaaactatt gaagagttgc acaatctcct tgtctctaag
    16741 gaaatttctg caacagaatt gacccaagca acacttgaaa atatcaagtc tcgtgaggaa
    16801 gccctcaatt catttgtcac catcgctgag gagcaagctc ttgttcaagc taaagccatt
    16861 gatgaagctg gaattgatgc taacaatgtc ctttcaggaa ttccacttgc tgttaaggat
    16921 aacatctcta cagacggtat tctcacaact gctgcctcaa aaatgctcta caactatgag
    16981 ccaatctttg atgcgacagc tgttgccaat gcaaaaacca aaggcatgat tgtcgttgga
    17041 aagaccaaca tggacgaatt tgctatgggt ggttccggtg aaacttcaca ctacggagca
    17101 actaaaaacg cttgggacca cagcaaggtt cctggtgggt catcaagtgg ttctgccgca
    17161 gctgtagcct caggacaagt tcgcttgtca cttggttctg atactggtgg ttccatccgc
    17221 caacctgctg ccttcaacgg aatcgttggt ctcaaaccaa cctacggaac agtttcacgt
    17281 ttcggtctca ttgcctttgg tagctcatta gaccagattg gaccttttgc tcctactgtt
    17341 aaggaaaatg ccctcttgct caacgctatt gccagcgaag atactaaaga ctctacttct
    17401 gctcctgtcc gcatcgccga ctttacttca aaaatcggcc aagacattaa gggcatgaaa
    17461 attgctttgc ctaaggaata cctaggcgaa ggaattgatc cagaggttaa ggaaacaatc
    17521 ttaaacgcgg ccaaacactt tgaaaaattg ggtgctatcg tcgaagaagt cagccttcct
    17581 cactctaaat acggtgttgc cgtttattac atcatcgctt catcagaagc ttcatcaaac
    17641 ttgcaacgtt ttgacggtat ccgttacggc taccgcgcag aagatgcgac taatcttgat
    17701 gaaatctatg taaacagccg tagccaaggt tttggtgaag aagtgaagcg ccgtatcatg
    17761 ctgggtactt tcagtctttc atcaggttac tacgatgcct actacaagaa ggctggacag
    17821 gtccgtacac ttatcattca agatttcgaa aaagtcttcg cggattacga tttgattttg
    17881 ggtccaactg ctccaagtgt tgcctatgac ttggattctc tcaaccatga cccagttgcc
    17941 atgtacttag ccgacctctt gaccatacct gtaaacttgg caggactgcc tggaatttcg
    18001 attcctgctg gattctctca aggtctacct gtcggactcc aattgattgg tcccaagtac
    18061 tctgaggaaa ccatttacca agctgctgct gcttttgaag caacaacaga ctaccacaaa
    18121 caacaacccg tgatttttgg aggtgacaac taatgaactt tgaaacagtc atcggacttg
    18181 aagtccacgt agagctcaac accaattcaa aaatcttctc acctacttct gcccactttg
    18241 gaaatgacca aaatgccaac actaacgtga ttgactggtc tttcccagga gttctaccag
    18301 ttctcaataa aggggttgtt gatgccggta tcaaggctgc tcttgccctc aacatggacc
    18361 tccacaaaaa aatgcacttt gaccgcaaga actacttcta ccctgataat cccaaagcct
    18421 accaaatttc tcagtttgat gagccaatcg gttataacgg ctggattgaa gtcgagctag
    18481 aagacggtac gaccaagaaa attggtatcg aacgcgccca cttagaggaa gacgctggta
    18541 aaaacaccca cggtacagac ggctactctt acgttgacct taaccgccaa ggggtacctt
    18601 tgattgagat tgtatctgaa gccgatatgc gttcgccaga ggaggcctat gcttatctga
    18661 cagccctcaa ggaagttatc cagtacgctg gcatttctga cgttaagatg gaagaaggtt
    18721 ctatgcgtgt ggatgccaac atctcccttc gtccttatgg tcaagagaaa ttcggtacca
    18781 agactgaatt gaagaacctc aactccttct caaacgttcg taaaggtctt gaatacgaag
    18841 tccaacgcca ggctgaaatt cttcgctcag gtggtcaaat ccgccaagaa acacgccgtt
    18901 acgatgaagc gaataaagca accatcctca tgcgtgtcaa ggaaggggct gctgactacc
    18961 gctacttccc agaaccagac ctacccctct ttgaaatttc tgacgagtgg attgaggaaa
    19021 tgcggactga gttgccagag tttccaaaag aacgtcgtgc gcgttatgta tctgaccttg
    19081 gtttatcaga ctacgatgct agtcagttga ctgctaataa agtcacttct gacttctttg
    19141 aaaaagctgt tgccctaggt ggtgatgcca aacaagtctc taactggctc caaggggaag
    19201 tcgctcagtt cttgaatgct gaaggtaaaa cactggaaca aatcgaattg acaccagaaa
    19261 acttggttga aatgattgcc atcatcgaag acggtactat ttcatctaag attgccaaga
    19321 aagtctttgt ccatctagct aaaaatggcg gtggcgcgcg tgaatacgtg gaaaaagcag
    19381 gtatggttca aatttcagat ccagctatct tgatcccaat catccaccaa gtctttgccg
    19441 ataacgaagc tgctgttgcc gacttcaagt caggcaaacg taacgccgac aaagccttta
    19501 caggattcct tatgaaggca accaaaggcc aagccaaccc acaagttgcc cttaaactac
    19561 ttgcacagga attggcgaag ttgaaagaaa actagacaga acaaaaccag ccctaaggtt
    19621 ggttttttct tctctaccaa ctcccaataa ctattttggc tttatttcca gagtatttta
    19681 tggtaaaatg aagagtaata atatttatta aagaggtaaa aacatgattg aagcaagtaa
    19741 attaaaagct ggtatgacct ttgaaacagc tgacggcaaa ttgattcgcg ttttggaagc
    19801 tagtcaccac aagccaggta aaggaaacac gatcatgcgt atgaaattgc gtgatgtccg
    19861 tactggttct acatttgaca caagctaccg tccagaggaa aaatttgaac aagctattat
    19921 cgagactgtc ccagctcaat acttgtacaa aatggatgac acagcatact tcatgaatac
    19981 agaaacttac gaccagtacg aaatccctgt agtcaatgtt gaaaacgaat tgctttacat
    20041 ccttgaaaac tctgatgtga aaatccaatt ctacggaact gaagtgatcg gtgtcaccgt
    20101 tcctactact gttgagttga cagttgctga aactcaacca tctatcaaag gtgctactgt
    20161 tacaggttct ggtaaaccag caacgatgga aactggactt gtcgtaaacg ttccagactt
    20221 catcgaagca ggacaaaaac tcgttatcaa cactgcagaa ggaacttacg tttctcgtgc
    20281 ctaatctcta gaaagaggtc attctatggg aattgaagaa caacttggcg aaatcgttat
    20341 cgccccacgt gtacttgaaa aaatcattgc tatcgctact gcaaaggtag agggtgttca
    20401 ctctttttca aacagatcag tgtctgatac cctttcaaaa ctttcactcg gccgtggcgt
    20461 ttatcttaaa aacgtggacg aagaactcac agcagatatc tatctctacc ttgagtacgg
    20521 agtaaaagtt cctaaggtag cggttgctat ccagaaagct gtcaaagatg ccgtccgtaa
    20581 tatggctgat gtagaactcg ctgctatcaa tattcacgtt gcaggtatcg tcccagataa
    20641 aacaccaaaa ccagaattga aagatctatt tgacgaggac ttcctcaatg actagtccac
    20701 tattagaatc tagacgccaa ctccgtaaat gcgcttttca agctctcatg agccttgagt
    20761 tcggtacgaa tgtcgaaact gcttgtcgtt tcgcctatac tcatgatcgt gaagatacgg
    20821 atgtacaact tccagccttt ttgatagacc tcgtttctgg tgttcaagct aaaaaggaag
    20881 aactagataa gcaaatcact cagcatttaa aagtaggttg gaccattgaa cgcttaacgc
    20941 tcgtggagag aaacctcctt cgcttgggag tttttgaaat cacttcattt gacactcctc
    21001 agctggttgc tgttaatgaa gctatcgagc ttgcaaagga cttctccgat caaaaatctg
    21061 cccgttttat caatggactg ctcagccagt ttgtaacaga agaacaataa aaagaaaaag
    21121 tgtttgatag atatcaaaca ctttttcttt gcctcccact atctaaaaaa atgataatag
    21181 atataattgt aaacaaaaat ccagataggt tttgcatgat tgagaaagtt aaaaaaacta
    21241 tggcagagaa tcgttaatct cagattgtcg gtagaacgat aaacaagggc aaaaaagaaa
    21301 ccaatcagac tataatataa taaactaatt ggatctctgt gagatagtat caaatggcta
    21361 atcccaaaga taaggcctga taagatgaca tctaaatagt actttgactt aggaaagaag
    21421 gtattcataa aataccctct atcaagagtc tcctcaaaaa caggaccgat gattacaagc
    21481 aggacaaaag ataagatagt cgataaaaag gttggttgtc catttgaaag aaccacggta
    21541 aaatactcat catgaatatt cctatggtta atcaaatgag catagcgtgc ctaaaaatta
    21601 ccgagaatct gataaaccac ataagttgca aataaggaga agacaaatga ccagtcccag
    21661 ctctttttct tttttaacct ccaaattaat agaaaaggaa acttcccact aatcccactg
    21721 ttaaaataag agaatagaca tcagctccta accctaaaat gatcgtcaca tacaatccaa
    21781 ttgtttgtgg taaataggta gatagtaaaa taataagcaa aaatattcca aattgtctta
    21841 gtttctttgt gtttctcatc gtactttttt gaaagattac cctgttcgga agccgtactt
    21901 ccaagcatct atataagaat taagtgcccc ttgcctcata tagggagcaa attctctata
    21961 atataaccat ctactatatc catcttccca aacagcaaga ccacctgaag tttgctccaa
    22021 gtcctcagtt gaaagaactg taaatgtttc tgtacctgtc attgcaagta ccttcttaaa
    22081 atagattgtt gtaggctcac atttatagta tatttctttt tttgtctatt ttatagtcta
    22141 tctcctcaac tggcaatttt tcgacctgaa ttgcattttt ccataaaaaa tgagaccttt
    22201 ctagtctcat ttagtcattc ttagtatttt ctaaatcgtt gatagcgttc ttccagcaac
    22261 tcttctagcg gtttttgtga aagtctagcc agctccgttt ggagttcttt tttgacactc
    22321 ttaattagtt ctttactaga aagtcctact tcagaaatca ccttatccac cacgtccatt
    22381 tctaacagtt catgcgaagt gattttcatc agttctgctg cttccatggc gcgagtaccg
    22441 tccttccata aaatggaagc aaagccttct ggactgagaa tggcatagat agaattttcc
    22501 agcatccaga cacggtccgc gacagctaga gccagagccc cgcctgaacc accttcaccg
    22561 ataataatgg cgataatagg aactttcagg tcactcattt ccatgagatt gcgagcgata
    22621 gcttcccctt gaccacgttc ttccgctccg acaccaggat aagcacctgc tgtattgata
    22681 aaggtcacaa ctggacggcc aaatttctca gcctgtttca tcaaccgcag tgcctttcgg
    22741 tagccttctg gatgtggttg gccaaaattc cgtttgaggt tgtcttgcaa actcttgcct
    22801 ttttggatac caaccactgt tacagcttgg tctccaagcc aaccaatacc accaacaact
    22861 gcaccatcat cacgaaaaga acggtcacca tgtaattgga taaattcatc aaaaatgcct
    22921 gtcgcaaagt ccaaggttgt caagcgactc tgctcacgcg cttctctgac tatttttgca
    22981 atattcatct aggactccct ccatgcaatc tgactaggct agcaatcgta tctggtaagt
    23041 ctcttctttt gacaatagca tccacaaagc catgttctaa taggaattct gccttttgga
    23101 aatcctcagg caagctttca cgaaccgtat tttcaatcac acgacgccca gcaaaaccaa
    23161 ccaagctctg tggttcagcc agaatgatat cgccttccat agcgaaagaa gctgtcacac
    23221 caccagtcgt tggatctgtc aaaatggtca ggtaaaagag accagcattt gaatggcgtt
    23281 taaccgctgc agagatctta gccatctgca tgagactcat gattccttcc tgcatacggg
    23341 ctccaccaga ggctgtgaat aggacaactg gtaatttttc gacagtcgca tactcaaaca
    23401 aacgagtgat tttttcacct acaaccgtac ccatagaagc catgataaaa ttagaatcca
    23461 taatcccaag agccacagtc tgacctttaa taagagcagt tcctgtcaca acggcttcat
    23521 gcagacctgt tttttcacgc atagatgcca gtttcttttg gtaaccaggg aaatgcaagg
    23581 gatccttgct ttcaatccct gtaaacaatt ctttgaaggt tcccatatca atcgtcaaag
    23641 ccaagcgttc ttgggcagaa atacgaaagg tatagctaca gtgcggacag atacgttcac
    23701 ttcccagatc cttctgatag atggtatgct tacagcctgg acactgggaa aataattcat
    23761 ctggaacctc tggcttagct tgaggttttt ccctaaccga acgattggga ttgattcgaa
    23821 tatacttatc ttttttacta aatagagcca ttgattcccc ttttcggttt aaactcttaa
    23881 agtcatttta ttctttttct tgatatttag gtaagaaggt ttccatcaag aaggaagtat
    23941 cataatcccc agcaatgaca ttgcgatctg aaatgagatc aagctggaaa tctgcattgg
    24001 tctgcactcc ttcaatctct aattcataga gggcacgttg cattttcatc aaggcgtcaa
    24061 aacgattttc gccgtgtact atgattttgg caatcatact atcataataa ggcggaatgg
    24121 tataacctgg ataaactgct gaatccacgc gcaagccaac tccaccactt ggcagataga
    24181 gattagtaat cttacctgga cttggagcaa agttaaaggc tgggttttct gcattgatac
    24241 gacactcgat ggcatgaccg cgtaggacaa tatcttcttg cttaacagac aaaggctgac
    24301 ctgccgcaat gcaaatctgt tccttaacga tatcaacacc tgaaacaaac tctgttactg
    24361 gatgttctac ctgaacacga gtattcatct ccatgaaata gaaattgcta cttgcttcat
    24421 caagaagaaa ttcaatggtt cctgcattct catagccaac aaactctgcc gctcgaacag
    24481 cagcagcacc tatttcatga cgcagcgttt ttccgattgc aatcgaggga ctttcttcca
    24541 aaaccttttg gttattcctt tgaagagaac aatcccgttc acccaagtga atcacatgtc
    24601 catgctcatc acctaggatt tgaacctcaa tgtgccgagc tggatagata acccgttcta
    24661 tgtacatggc accattgcca taattggcct tggcctcact agaggcagtt tcaaaggcag
    24721 aaacgaggtc atctggtttt tcaaccttac gaatcccttt accacctcca cctgctgaag
    24781 ccttgagcat aacaggatag ccaatttttt cagcaacaat caaagcttct tcagagttat
    24841 gcacttctcc atctgaacct ggtataacag gcacacctgc tttaatcatc tgagcacgcg
    24901 cattgatctt atcccccatc atatccataa catgaccaga tggaccgata aacttgatac
    24961 ctacttcttc acacatggtc gcaaatttgg aattttcact gagaaatcca aaaccagggt
    25021 gaatagcttc tgcctcagtc aagactgcag ctgatagaac tgcattaata ttgagataag
    25081 actctgttgc cttgccagga ccaatacaaa ctgcttcatc tgccaacagc gtatgaagag
    25141 cttccttatc agcagttgaa taaaccgcta ccgtcgcaat ccccaattca cgtgccgcac
    25201 ggataatacg aaccgcaatt tcaccacgat tggcaattaa aatttttcga aacatggaga
    25261 acctccttag ttcccaattg caaaagtaag ggtaccactg gctgcaagct tgccatccac
    25321 ttcagccttt gcttcaacca cagctatggt gccacgacgt tttacaaaag tcgctgtcat
    25381 aaccaattgg tcgcctggta caacttgctt cttgaactta accttatcca taccagcgta
    25441 aaagaccagt tttcctttat tttcaggttt tgataactcc aacacaccag cagtttgcgc
    25501 caaggcttcc ataatcagaa cacctggcat aactgggtat tgaggaaagt ggccgttaaa
    25561 gaaaggctcg ttgatggtca catttttgat agcaacaatg gtatcctcgc tcacctccaa
    25621 gacacggtcc actagaagca taggataacg gtggggaagg gcttctttga ttccttgaat
    25681 atcgatcatt tgatacgtac caatccttta ccaaactcaa ccatttcttc gttagagacg
    25741 agaatttccg ttaccacacc atccttagga gctgggattt cattcatgac tttcatggct
    25801 tcgataatta ccaatgtttg accttttttg acactatcac caactgtaac gaaggcaggt
    25861 ttatctggtc cagcagccaa gtaaaccact ccaacaagtg gactctctac aagatttccc
    25921 tcactagcca cacttgcttc agctggagct ggaacttctt ctgctacagt ctctgctgga
    25981 gcagatgtag gagctactgg actcggtgtt gctagaacgg gtgctggagc gacttgagtt
    26041 gcaacttcag gcacaggtct cgcttcattc ttgctaaact gcaactcatc cgtcccattt
    26101 ttataagaaa attctctcaa acttgactgg tcaaattgag tcatcaagtc tttaatatcg
    26161 tttaaattca tacttatcta ttctcccaac gtttgaaagc aagaactgca ttgtggcctc
    26221 caaaaccaaa agtatttgaa atagcgtatg gaatttcttt ctccaagcct tgtccataaa
    26281 cgacattagc ttcgatataa tctgatactt cacttgtccc agctgtcatt ggtacaaagt
    26341 tatgacgcat agcttcgatg gtgacgatag cttctactgc acccgcagcc cccagcaaat
    26401 gtcctgtaaa agacttggtt gatgatacag gtacttcctt accaagaaca gctacgatag
    26461 caccactttc tcctttttca ttggcaggag ttgacgttcc gtgagcattg acataggcta
    26521 cttgctctgg agaaatctca gcttcttcca aggctagttt gatggccttg atagctccct
    26581 gaccttctgg atgtggagaa gtcatgtggt aggcatcaca agtatttccg taaccaacca
    26641 cttcagccag gatagtagct ccacgttttt cagcgtgttc aagactttct agaaccaaca
    26701 tccctgaacc ttcacccata acaaacccat tgcgatcctt atcaaatggg atcgaagcac
    26761 gagttggatc ctctgtagta gagagagctg ttaaggcttg gaaaccagcg atggcaaaag
    26821 gtgtgataga agcttctgtt cctcccacca acatcacatc ttggaaacca aacttaatgg
    26881 agcggaaggc atccccaatc gcatcatttg atgaagagca ggcagtattg atagatttac
    26941 aaacaccgtt tgcaccaaaa cgcatggcta cattcccaga agccatattt ggtaaagctt
    27001 ttggaagagt cattggtttg acacgtttgg gtcctttttc atgaaggcga agtacctgat
    27061 cttcaatttc cttgattcca ccaataccag atgcaacgat aacaccaaaa cgatccctat
    27121 taagagcctc tacatcaaga ttggcatgat ttacagcctc ttgggctgca tacaaggcat
    27181 ataaagaata gttatcaaaa cggttggtat ctttttttac aaagtattta tcgaacggaa
    27241 aatcttggat ttctgccgca ttatgcacat caaagtcact atgatcaaat tttgtaatgc
    27301 caccaatgcc gattttccca gttgctaaac tattccaaaa ttcttctggt gtatttccga
    27361 ttggagatgt tactccataa cctgttacca ctactcgatt tagtttcatt cttttcacct
    27421 ctagctttcg ctacatactt aagccaccat caatggcaat cacttgacca gttagataat
    27481 cttggcctgc taaaaatact gtcaaatctg caacctgctc tgcctgccca aattctttca
    27541 tcggaatctg agctagtgta gcttccttaa tcttatctga taagatagct gtcatatcag
    27601 actcaatcat tcctggagca atcacattga ctcgtatatt ccgactagcg acctcgcgtg
    27661 ccacagactt ggtaaagcca atcaagccag ccttagaagc agcatagtta gcttgaccaa
    27721 tattccccat caaaccaaca acactagaca tattaatgat agcaccttct ctggctttca
    27781 tcatcggttt caagactgat tgtgtcatat taaaggcacc agtcagattg accttgagca
    27841 ctttttcaaa atctgcttct gtcatcttga gcataagagt atcttgggta atccctgcat
    27901 tgttgaccaa aacatctact gaacccagtt ctgcaatagc ttgatcaatc atacgcttag
    27961 cgtctgcaaa atctgataca tctcctgaaa tgggaaccac cttgatacca tagtttgaaa
    28021 actcagcgag caattcttct gagattgccc cacgactgtt taagacaatg ttggctcctg
    28081 cttgagcaaa cttgtgggcg atggcaagac caattccacg actcgaacct gtaataaaga
    28141 tatttttatg ttctagtttc atttttttcc tttcaaaact tctacttatt ttagtctatt
    28201 tttctaaaag tgctactaaa ctcgcttgat cttccacatg agctaagtga gcagtttgat
    28261 caattttttt aacaaaacct gacaagactt tccccggtcc aatctcgata aagttgctta
    28321 tgcctgcttc ttgcatgacc ccaatacttt catagaaacg aacgggttcc ttgacctgac
    28381 gcgtcaagag ctgagcaatg tcctcttttt gcatcacagc agcttctgta ttgccgacta
    28441 ggggacaagt aaaatctgaa aaacttacct gagctagagt ttcagctagt ttctggctag
    28501 caggctcaag gagagcggtg tgaaagggac ctgacacctt aagaggaatc aagcgtttgg
    28561 cacctgcttc ttgcaaaagt tcaaccgctc gatcaactgc aaccacttct ccagcaatga
    28621 cgatttgtgc aggtgtgtta tagttggctg gagtaaccac tccaagttca gaagcttttt
    28681 gacaggcttc ttcaatgacc tctactggcg tattgagaac tgctaccatc ttgccagagt
    28741 cagcaggagc cgcttcttcc atataggctc cacgcttagc taccaaggca accgcatctt
    28801 caaaatccaa ggcgccgctt gccaccaagg cagagtattc tccaagagac aaaccagcaa
    28861 ccatatcagg ctgatagccc ttttcttgca ataaacggta gatagcaacc gaagtcgcta
    28921 gaatggctgg ttgcgtatag cgggtctgat tgagtttgtc ttcttccgta tcgatgagat
    28981 aacgtaaatc ataaccgagc acctgactcg ctcgatcaat cgtttcttta acaatcggat
    29041 actgatcata gaaatcccgt cccatcccta gatactgggc accttgacca gcaaataaaa
    29101 aggctgtttt agtcatttct tacaactcct gcccagcgag aggcttcttc ttgaattttc
    29161 ttagcggctc cgtaatacaa atcttttagg atttcttcag ctgtttcttc tttagaaaca
    29221 agccctgcga tttgacctgc catgacagag ccaccctcca catcaccgtg aacaactgct
    29281 ttggctaggg cacctgctcc catttgttca aagatttcta aatcaggatc ttcctgctta
    29341 aaggcatctt tttcagccag ttcaaaatct ctagtcaact gatttttaat agcacgaaca
    29401 gcatgaccaa agtgctgagc tgaaatcgta gtatcaatat cccttgcttt taaaattttc
    29461 tctttgtagt ttggatgggc attcgactct tttgcaacta caaaccgtgt ccccacctgt
    29521 acagcctctg cacctagcat aaagccagcc gcagcacctt caccatccgc aattcctcct
    29581 gcagcaataa caggaataga tatagctgtg gctacctgtc gcaccaaggt catggttgtt
    29641 aatttaccga tatgcccccc agcttccatt ccttctgcaa taacagcgtc tgcaccgatt
    29701 ttttccatgc gtttagctaa agcgacacta ggaacaacag gaataacgat tatcccagct
    29761 tcatggaaac gttccatata cttgcttgga tttcctgctc ctgttgtgac aactttaaca
    29821 ccttcttcaa taacgagatc cacgatatct tccacaaagg gagataagag catgatgttg
    29881 accccaaagg gtttatcagt caatgatttg attttatcaa tattggcctt gacaacttct
    29941 ttcggggcat ttcccccacc gataattcct aatcctccag ccttggaaac agcccctgcc
    30001 aaatcaccat cagcaaccca ggccatccct ccttggaaaa taggatagtc aatcttcaat
    30061 aattctgtaa tacgcgtttt catagtgcct ccaaccttcc ttgcttacgt aatagttcga
    30121 tttcaccata atttgacagt caaactatta cctaaacaag agggagtggg tttctcccta
    30181 ctccttctac taatattctg cttattttgc ttgctcttca acgtaagcaa ccaagtcacc
    30241 aactgttttc aagtcatttt ctgcttcgat ttggatatca aaagcatctt cgatttctga
    30301 gattacttgg aacaagtcca atgaatctgc gtccaaatca tcaaaagttg attcaagtgt
    30361 tacttctgat gcgtcttttc caagttcttc aacgataatt tcttgtactt tttcaaatac
    30421 tgccatgata ggactccttt aaaataaata gtttttttat aacaatgtgt tcaccacatg
    30481 attacctaaa ttgtaagaat gagcgtgccc caggtcaagc ctccaccgaa gcctgataga
    30541 agaacagttt ggctaccatc taaagggatg agaccttgtt ctacacactc tgaaagtaaa
    30601 atcgggatac tggctgcact ggtattgcca tattccatca tattagctgg aagtttggct
    30661 cggtcaacac caatttttct agccatctta tccaaaatac ggttattggc ttgatgaagt
    30721 agcagataat ccaagtctgt cacctctata ggagattcat caatagtctg cttgatagac
    30781 ttggctacat ctcgaatggc aaaatcaaag actgtgcgtc catccatctt caaaaatgaa
    30841 tctgcacttt cttgatctga aaatggagaa tgcaaacctg aatgcccata agttaaacac
    30901 tcgctgcgac ttccatcgct attgagactc tcagctaaga aatgctcttg ctcgctagct
    30961 tctaacaaga caccaccagc accatctcca aacaacacag ctgttgatcg atccgaccaa
    31021 tcgactgcct tagagagggt ttcactacca atcaccaagc ctttttgaaa gcgaccagaa
    31081 gcgataaact tttcagcagt tgaaagagca aatacaaatc cactgcaagc cgcggttaag
    31141 tcaaaagcaa aggctttatt agcaccaata ttagcttgaa cacgagcagc tgtagagggc
    31201 atcatcgaat ctggagtaat ggtagctagg atgataaaat ccagttcttc tcctgttatt
    31261 ccagcttttg ccatcagttt cttagcaacc tctgtagcca aatcactggt agattctgtt
    31321 cttgaaatat gcctttgtcg tattcccgtt cgacttgaaa tccactcatc attggtatcc
    31381 ataatctgag ccaagtcgtg atttgtaacc acttgctctg gcacataatg agcaacctga
    31441 cttatttttg caaaagccat tatttcaaat cctccaaaaa ttggtaaaga ttagtcaaac
    31501 ctttacccat gacagcaatt tcttcctcgc tcatgccatc aataattttt tctaccatgg
    31561 ccttgtggaa gcgtttatgc agtctatgaa tcaagcgacc cttctttgtc aaatgcagat
    31621 gcaccacacg acgatcctgt tctgaccgaa ctcgctcaat gtagccctta cgctctaaat
    31681 tgttcaaact tgtcgtaaca gttccaagag ttaccatcaa ctcttttgac acttgacttg
    31741 gagtcacatc tggagcctta ccgatgacat caatcgtatg catttctttg atggagatat
    31801 ccttaaaacg actacctctc aagttcactt cctcaattac aaggacattg ttaaatatag
    31861 atgttaaata ttcattgatt cgttggtagt ccatttttca tatccctcct tcttcaaaaa
    31921 acttttacaa tcaaaacatt tgacagaaag aattatatca aaattcaaag aatgatgcaa
    31981 gtatttttta ttttcctgta aatttaggtc ttcttctctc cgaatgagct cgcactcctt
    32041 ctttgaaatc ctctgtttga gctaaggatt tctgtaggtt cagttctaaa gtagcgtaac
    32101 cctgccagtc tttaaattgg ctctcccaaa ccaacttctt aatggcagca taggaattac
    32161 ttgaagcacg tcttaatttt ttaagaagct gttctctcgt cttttcaagt ttttcagctt
    32221 cagaaacgcg gtaaaccaac ccccattcta gggctttttc tgccgttaaa gcctctcctg
    32281 tcatagctaa ttgagcagca cgcgtcacac cgatactgcg gctcaagaga tgaattcccc
    32341 ctgcatctgg agccaaacca acaccaacaa aggcttggat aaacttagcc ttatccgtcg
    32401 ccaaacagaa atctgccgca acagccatat tcgctgcggc acctgcaaca gcaccgtcaa
    32461 cttccattaa aacaggtttg gctatttgct tgattttata agaaatcgta ttgaccaact
    32521 ctgcgatttt tgtcaatgat ggaatatcat cctcatccac tgcccgcttc atctctacca
    32581 aatctccccc aactgagaag acctttccat tggcattgat taagataaaa tgcacagctg
    32641 gattttcttc tgccaaagtc agagcttcta aaatctcctc acacatggga atatgaaaac
    32701 catttgcgac ctcaggacgg ttcaaggtaa ggattgccaa gtcctcttca agctgataaa
    32761 taatgtgttc catcagggct cctttttatt ttataagcag tttatactct tcgaaaatct
    32821 ctttaaaccg cgtcagcttc catctgcaac ctcaaaacag tattttgagc tgacttcgtc
    32881 tagcttctta gtttgctctt tgattttcat tgagtgttaa attatttcac tgtcaaagta
    32941 tatctttttt aggagcagaa agcaagaaaa aatcgactga aagtgtctca gccgataaga
    33001 aaggctcgct ttaggctaga aagcatctta ttttcttcat tgaaaaaagc ctttctttct
    33061 gctataatcg tataaaatac ttactttagg agttcttatg aaagttgtta aatttggagg
    33121 tagttctctt gcctctgcta gtcaattaga aaaagtttta aacatcgtca aaagcgattc
    33181 agagcgtcgt tttgtagtcg tttctgcgcc tggtaaacgc aatgctgaag atactaaggt
    33241 tacggatgcc ctgattaaat actaccgcga ctatgttgcg ggtaacgata ttagcaagag
    33301 ccaaagctgg attatcgacc gctatgctgc tatggttagt gaattgggac taaaaccagc
    33361 tgtgctagaa aaaatttcta aaagcattca cgccttggcc actcttccta ttgaagaaaa
    33421 tgaatttctc tacgatactt tcctagcagc cggtgaaaat aacaatgcca aattgattgc
    33481 tgcctacttt aaccaaaatg gtatcgatgc acgctatatg caccctagag aagctgggat
    33541 tgtggtcaca agtgaacctg gtcacgctcg catcattcca tcaagttatg acaagattga
    33601 agaattgaca aacaccaatg aagtccttgt cattcctggt ttctttggtg tcactaagga
    33661 aaatcaaatc tgtactttct cacgtggagg ttctgatatt acaggttcta tcattgctgc
    33721 tggtgtcaaa gctgacctct atgaaaactt tacggacgtt gatggtatct ttgcagccca
    33781 ccctggtatt atccaccaac cacactcgat tcctgagttg acctaccgtg aaatgcgcga
    33841 gttggcctat gcaggcttct cagtccttca tgacgaggct cttcttcctg cctaccgtgg
    33901 aaaaattcct ctggttatca agaataccaa caaccctgac catccaggta ctcgtatcgt
    33961 tctaaaacac agtaatgatg aatttccagt tgtgggaatt gctggtgact caggctttgt
    34021 cagcattaac atgtcgaaat acctcatgaa ccgtgaggtt ggatttggcc gcaaggttct
    34081 gcaaatcctg gaagaactta acatcggttg ggaacatatg ccaacaggta tcgacgatct
    34141 ttctatcatt ctccgttctc gccaactaac tcccatcaag gaagaagaaa tcctgcgtca
    34201 gttggttcaa aaggctaaag tagatcatgc agaaatcgaa cacgaccttt ctatcattat
    34261 gattgttggt gaaaaaatga agagccatat cggagtgact gctactgcga cacgcgctct
    34321 atctgaaaac aaaatcaaca tccagatgat gtctcaaggt tctagtgaag tttctattat
    34381 gtttgttgtc aataaagacc aagagaaagc agcaattaaa gccctctaca atgccttttt
    34441 tggagaaagt aaggaagact aagcatggcc caatcactta acaaaacagt actcctcagt
    34501 acgacaggca cttcctacct ctctatcgct gggaaagttg ggaaattcct tgtcggagat
    34561 caggctttgg aattttaccc agatgtcaat gtcgaacaat ttatccagat tccttggagc
    34621 catatcaatc agattggagc caatgtcact ggacgcaaaa tcagccgcca cttcgaagtc
    34681 tttacagaca aaggaaaatt cctctttgct tcaaaagact caggtgccat tctcaaaatt
    34741 gcacgcgaaa aactaggcaa tgacaaggtc gtcaaacttc cgaccctgat tcagacaatt
    34801 agccaaaaat ttaaaaatct atttgcaaaa aagtagaaac tttagtataa tcatagcaac
    34861 ggataagtag gttatcttct tctttcagaa agtctgcggg tactgcgagc agataggggg
    34921 gataggtgaa attctaccgt tagtaacaat tacatacaca atcaagtgca cacctgtgaa
    34981 gttggatgga accgtggccc tgccactcca acgttttgtc aggcgtgctt ttttcataaa
    35041 ggagttctta tgttagatat caaacgtatt cgtacagatt ttgaagctgt cgcagaaaaa
    35101 ttagctacac gtggtgtaga tgctgctgtc ttgaatgaaa tgaaagaaat cgatgctaaa
    35161 cgtcgtaaca tcttggtcaa ggttgaaact ctcaaagcag aacgtaacac agtttctgct
    35221 gagattgccc aagctaagcg caacaaggaa aatacagatg acaagattgc tgccatgcaa
    35281 aatctatctg ctgaggttaa agccttggat gctgaattgg cagaaatcga tgctaaattg
    35341 acagaattta caacgactct tccaaatatc ccagctgaca gcgttcctgt tgggactgac
    35401 gaagacgaca atgtggaagt tcgccgttgg ggtactccac gcgagtttga cttcgaacct
    35461 aaagctcact gggatctcgg tgaagacctt ggtatccttg actgggaacg cggtggtaag
    35521 gtaacaggcg ctcgcttcct cttctataaa ggcctcggtg ctcgtttgga acgtgctatc
    35581 tacaacttta tgttggatga acatggaaaa gaaggctata ctgaagtcat cacaccttac
    35641 atagtcaacc atgattctat gtttggtact ggtcagtatc caaaatttaa ggaagatact
    35701 tttgaactca gcgataccaa ctttgtcttg attccaactg ctgaagttcc tctgacaaac
    35761 tactaccgtg atgaaatctt agacggcaaa gatcttccaa tctacttcac tgccatgagt
    35821 ccgtcattcc gttctgaggc tggttctgcc ggtcgtgata cgcgtggctt gatccgtttg
    35881 caccaattcc acaaggttga aatggtcaaa tttgccaaac cagaagaatc ttacgaagaa
    35941 ttggaaaaaa tgacagccaa cgctgaaaac attcttcaaa aactcaacct tccataccgt
    36001 gtcgttgctc tctctactgg agatatgggc ttctcagctg cgaagactta cgacttggaa
    36061 gtgtggattc cagcacaaaa caattaccgt gaaatctcaa gctgttcaaa cacagaagat
    36121 ttccaagccc gtcgtgccca aatccgttac cgtgatgaag cagatggcaa ggtgaaactc
    36181 cttcatacct tgaacggctc tggacttgca gttggacgta cagtggctgc aattcttgaa
    36241 aattaccaaa atgaagatgg ttctgtgacc atcccagaag cacttcgtcc atacatgggt
    36301 ggagctgaag tcatcaaacc ataaaaaata aggtttagct atttctagct agaccttttt
    36361 tcgtaaccaa atcagataag cacctagtac aaagaataaa atagttaggc atataatggt
    36421 ttcagccaat accaggtaat ccagaaatgg aagtttcaaa attccctgag ccatcttgag
    36481 cgaggtcgct gtgataatgg ttgggaaggt gagggctgag agggctggtt gaaaaccttg
    36541 ttttaaaatg ttgggcagac gagttaaaac aaagaaaaag aaggattgag aagccaaaat
    36601 catgacaatc aagacccaag tcggcaggct ggttcctcct actcgaacta gagaagccaa
    36661 gagtagagag aaaggagcac agtagattcc ttcttgtcca agcaaggcta gtgggagtgg
    36721 atgtttcttt aaatcgctat aaataagggg atagagatag aaggtcaaga gaaaaccaaa
    36781 actcaaggtc gcataggcaa tttcgataat acctaccaga ggataggtca aggcagccac
    36841 tgctatcccc acatagagaa ccgtccaact tggagtggca tgaaccctcc gccctgaaca
    36901 agcaaacttg atggtaaaac cagcaatcaa ggtcaaatcc aagagaaatg aaaaccacca
    36961 aatcccttgt gctaccaaag gaagataaga gaatacgcga aagacatagg tcgataaaat
    37021 catcccagcc ataggaaagg ttgccattcc tgacaaaaga gggggcttgg tcaattcttg
    37081 cttggtttct ttccaattaa agagatgcag aattagaaag taaatccata aaaccaaacc
    37141 agtcagacta aaaagatggg atagaaccgg caacgtatct aaaataagat ttccagctcc
    37201 tgccaaacct agcaaacaac ctgaaaatac taaggggagt tttttcatcc taacctccaa
    37261 taatcatgtt agtttcagta taacataaaa gcgcttaaat gaggatttaa aaaaacgaag
    37321 tccgcttatt tcagacttca ttttactcag atatgaatta ggcataaggt tgcaattctg
    37381 gattaattgg tgtattagct aagttgttgg catagttaca gaggattgct aggctgacac
    37441 caaaaaccac atccaaggca ttttgttgag tgtagccagc ttctaaaaac tcagacaagg
    37501 cttcatctcc tacacgaccc ttggtattga taactgccaa ggtaaactta gctagggtat
    37561 ccaatttagg atctgtttca attggagtac gattgcgaag agcttgaatc aagtcatcat
    37621 tcatctggat ttgtttgatg gaaaaggctg tgtgacctgc gacacagaag gcacaaccat
    37681 tggtcacggc tgccgtgatt tgcaccactt cacgctcaac gggtgtcagg ctgttgcgac
    37741 ggtggataga tgagacaatt tggtaggctt ctaaaacagt cggggcattg gccaagagac
    37801 cgattaggtt gggaatatag ccattgttgt ctttttctac tgtttcaaga atttctttca
    37861 cttctgctgg tgctgactct actgtatgga tagtaaatgt tgtcataaga tacctctttt
    37921 cttattattg acactaatat tattggaaaa tcttataaaa tcctgattcc taagtttatc
    37981 taagataaag ctttattctc tcataagatt ttcgttgtta tattagttta tcacacttcc
    38041 aatcacttgc ataatatata ttatatatca ggctgataaa aattatttat aggcaaaaaa
    38101 atcacacgag ctgtgtgatt ccattatttg tcaaaatact ttttagtttc agcaataacg
    38161 actggcgaca agaccaagag ggcaatcaag tttggcagag ccatcaaggc gttaacgata
    38221 tctgcgataa tccagaccat atccaactcg ataaatcctc ctaacaagac catgagcaca
    38281 aaaaacacac ggtagagcca gataaagcga gccccaaaga ggaactcaaa acagcgttct
    38341 ccgtaatagt tccaacctag aatcgttgta aaggcaaaaa gtacaaggaa gatggtcaag
    38401 agggcaggcc caaagtgtga aaagactgtt gagaaagctg actgagtcaa ggcaacccca
    38461 ttcaagtcac cactccaaac tccagttacc aagatggtca aaccagttag agtacaaatg
    38521 atgagggtat caataaaggt tcctgtcatg gaaatcaaac cttgctctac tggttcattt
    38581 gtcttggcag ctgcagctgc aataggagca gaacccagac cagattcgtt tgagaacaca
    38641 ccacgcgcca caccattttg aatagccatc cgaacgctag caccagcaaa tccacctacc
    38701 gcagcaaggg gactaaaagc tgaggtaaag actaaagcga ttgtgccagg gatttttccg
    38761 atattaaaga aaataactgt aagagttcct aagatataaa tgagggccat aaaaggaaca
    38821 acagtagttg aaaccttaga aatagacttg agtccaccaa agactgcaat cgctacaaag
    38881 acagacaaga cgagagctgt gatggctggc gaaatcgtcg ttgtattttg gatagattct
    38941 gtaatcgagt tgacttgggt gaaggttccg attcccaaga gagcaaccaa tactcctgct
    39001 actgcaaaca aaacagcaag tggtcgccac ttttctccca tccctagaag gatatagtgc
    39061 atgggacctc ccgctactgc accatggtcg tccttggtgc ggtatttgat ggccaagagt
    39121 ccttccgcat acttggtagc cattccaaag aaagccgcca tccacatcca aaatagagct
    39181 cctggtccac caaccttgat agccgtcgca actcctatga tatttcctgt tccaacagtt
    39241 gatgccaagg ctgtacacag agctgcaaaa ctggatacat caccatgtcc cttatcctgg
    39301 ataaaaataa gctgaaaggc cttgggcaga cgcaaaacct gcaagagtcc tagccgcatg
    39361 gttaggtaaa tccctgttcc gaccaataaa atcaagaggg gcggtcccca agcaaaagca
    39421 tcgattgatt taagcaattc taacatttcc ttctcctatc gtttcaaccc caaaagaaag
    39481 agcacatgca agatacatgt actctggaat gcttagataa atgctaaaaa gcggtctatc
    39541 ctagctctgt ccttttacct gagagtttga gcagttgcct gccttgcccc ttcggtgcct
    39601 ttacggtctc tccagagttc cgtccattta cagtcatgga aaatcaaacg attccccact
    39661 tctattaaac ttcattcggt gttggtattt aattgattct aattttacaa aaaatgttgg
    39721 cttttgtcaa tgtgtttatt agtaaaaatt agttcaacag tttttacttt ataaagtcca
    39781 gaatactgct atcctttaaa agtgacaata gtcgcaccac tgcctccagc attttgtggg
    39841 gcatagccga aactcttgac atgtttgttt ctttgcaagt atttggtaac tccttcacgg
    39901 atgactcctg ttccgatacc atggatgata tcaacttgag ccatattgtt aagcaaggct
    39961 tggtcgatga aggtatctag ctcattcatg gcttcttcat agcgcttgcc tcgaagatcc
    40021 agtctagctt gaggtcctcg cccagaagtt cgtttcacaa cattgacctg tttcttcttg
    40081 actggttttt cttgctgggc ttgaacaaga tcaaactctt tctcttccaa ggtcatctta
    40141 atcaagccaa cttgggcttc ccagcgaccg tccttgagtt gactggtcaa ggtaccacgc
    40201 tgaccataac tgagaaccac gatatcatct cccacctttg gagctcgttt tttcttggcc
    40261 ttttgaagga ccttattttt agacaagtcc actttttcag gagccaattt tttcaacttg
    40321 gccttggctt caatgatttc gtggggcttg agttgggatt tactgtggag atttttgaga
    40381 atctggtcac tttcacttag ggccatatcc acaatctcag cagcctgttc acgcgccttg
    40441 ttaagctcgg tttccttttc acgattaagc tcgttgtaga gtttttttag cgcacggttc
    40501 atcttgagat tttcttgctc cacctcacgg atattgtcca aacgtttgcg gctttccagc
    40561 gtctgctctt ctaattgctc aatgatacga ttgacgtcat tgtcctgatc gatctgctga
    40621 ctggcatctc ctacgataac ttcagatagg cctagacgtt tggcaatttc aaaggcatta
    40681 cttcggccag gaacaccctg cataaagcga taggtcgggc gaagagttgc agtatcaaac
    40741 tccatactgg cattttgcac aaaggctgtc tcaataccgt aggccttgag ttctggatag
    40801 tgggtcgtcg ccatggtctt gatttgacgc aggcgaaggt cctccagaat agccatggca
    40861 agggctgctc cctcttgggg atcagtacca gcccccaact catccaaaag taagagtgaa
    40921 tgttggttga ccttgccaag aatatccacg atattggtca tatggctaga gaaggtagac
    40981 aagctctgct caatagactg ctcatctcca atatcagcaa agatttcttc aaaaatacca
    41041 acacgacttc ccttgtctgc taaaatcggc aatcctgact gggccatgac ctgtgtcaag
    41101 cccagagttt tgagcatgat ggtcttccca cctgtattgg gacctgtaat gacaatagct
    41161 gttaaatctt gaccaaaatg gacatcattt gcgacggcat ttttgaccaa aggatggcag
    41221 acatggagca gttgaatctc ttgattttct gacagctgag gcacgactgc ttgtctttct
    41281 tggataaatc gaaccttggc acgaatcaag tccagatgac cgataatcca agcgtcatta
    41341 gcaatctcag ccgcatgagg gcggacacgc tcagaaattt cttggagaat gcgaagcatt
    41401 tcatagcgct catctgctcg cagactagca atttcttcgc tcagtttgac tacctcacgt
    41461 ggttcgatat agacggtgtt tccactagca gaaatatcat gaacgacacc tgcaatctta
    41521 ttgcggtagg tgtttttgac tggtaaaacc tgacggccat ttctgctagc aacaattcct
    41581 tccgtcaaca tctgcgcttt ttgcttgagc aagtcttgta aaacatcgcg tacctgactc
    41641 tcgctatcat gtatttttcg acggattcgc gccaattctt cactggcaaa attttcaatg
    41701 aaacccgcat cattaaaggc ctgaagattt ccttgtaatt gcggaaaatc atgtaatttc
    41761 tcaaaccaaa gggctaattc ttccaagctg acattttcca gattggcata aaaactttga
    41821 agttctcggc tggcaagaag cacgcgtttc aagagtagga actcctcgat attgagatcc
    41881 gctcccatct ccaacctctt gcagactcct gcaatttcct tagttgagag aatagtaaaa
    41941 tgcggttgct cgacgaaaag agcctgcatt tctttcatct cagcaaaagc ctgtttgatt
    42001 ttatctgctt tggcagtcgg agccagctgt ctcaattgct ccaagccctg ctcggtcaac
    42061 aaatgaggat caaacaaggc cttgacctta tcgaactcta atgtttctaa tattttctta
    42121 ttcatcttta tttccttgtc tttgaatgtc taggtgtggt agctttttac attctgatag
    42181 attcgagtca aatctgtaaa caaagggcta ggaaaactcc tgcccttttt atccgattaa
    42241 atttgtcacc cagatttgtt tgagccaact ggttgttatc ggtatgctct ggatgatgtg
    42301 ttttgcgacg atactctttt caagaggatt ttgtataact gccatgggga tggtcgccaa
    42361 gattgtcaag gccatttgca agacaaataa ggtcaccaac atggacaaga tacctgctga
    42421 aacttggaac aacttaccac ccagtttttt gctaggaatc aagtgtaaga gaagaccaag
    42481 caaacgacca atgctataga aaatcccaaa tacaagcaag tagccgatac ctgcataaaa
    42541 gaccttatcc agctgaaaga gttgatccga tgggaaaaag aaagtcccct gaccttcctg
    42601 cgaatttgca taagggagca ataaatggaa ttgctctcca agccccttat aaaactggcc
    42661 agccataaaa gccgatgcca tggctgaaat caggtaataa acctgtaaga gcaggcctct
    42721 ccgatagccg atataaaatc cccaaaccaa gaccaataga agaaggaatg aaatcataag
    42781 gaatcctcaa tcttgctctg ttcttgctta caagtcacaa gcttgtgacg gagttcttct
    42841 agctcttgct ccttatcgtc aaattcaatc tcacggctga gctgagttga taaacagttg
    42901 actgccaaca aaagagcgat tgtttcatca tctgcgctag gcatttgttc tttaattgct
    42961 tggtattttt ctgtcgcaac cttagcgatt tcctccataa aaaggttatc atgttcgctt
    43021 gtcaaggtta acgatttttt cccgaatgta aatttgaatc gatttagatt tgccataaaa
    43081 ttcacctcac gatattatac caaaattcgc taattttgtc agtttttaca aattttactg
    43141 cttttgtggt acaatagaaa ctatggcaag tatcacactc acaccaagcg aaaaggatat
    43201 tcaggctttt cttgaacact atcaaaccag tctggctccc agtaagaatc cctatatccg
    43261 ctactttttg aaactacctc aagcaacggt ttctatctat acttctggaa aaatcttgct
    43321 tcagggtgaa ggggctgaga aatacgctag tttctttggc tatcaacttg tagaggaaaa
    43381 cagggggcaa aatcttcctt taattgggac agatgaggtg ggaaatggtt cctactttgg
    43441 tgggcttgca gttgtggctg cctttgtcac atctgaccag cacgactttt tacgaaaact
    43501 cggtgtgggg gattctaaga ctctgaccga ccaaaagatc cgtcagattg ctcctattct
    43561 caaggaaaaa atccagcacc aggcactcct tctctcaccc agcaagtaca acgaggtcat
    43621 cggagaccgc tacaatgctg tttcggttaa ggttgccctc cataatcagg ctatctatct
    43681 cctccttcaa aaaggtgttc agcctgagaa aattgtgatt gatgccttta ccagtgctaa
    43741 aaattatgac aagtacttgg cacaagaggc caatcgtttc agcaatccta tcagcttaga
    43801 agaaaaggct gagggcaaat acttgtctgt cgcagtttct tctgtcattg cgcgtgatct
    43861 ctttctggaa aatcttgaaa atttgggacg agaactgggt tatcagctcc caagtggagc
    43921 tggaacggct tctgacaagg tggctagcca gattttgcaa gcctatggta tgcagggact
    43981 cagcttctgc gccaaattgc actttaaaaa cactgaaaaa gcgaaaaaac gcttagaaag
    44041 gtaagttatg aattcattta aaaatttctt aaaagagtgg ggattgttcc tcctaattct
    44101 gtcattacta gctttaagtc gtatcttttt ttggagcaat gttcgcgtag aaggacattc
    44161 catggatccg accctagcgg atggcgaaat tctcttcgtt gtaaaacacc ttcctattga
    44221 ccgttttgat atcgtggtgg cccatgagga agatggcaat aaggacatcg tcaagcgcgt
    44281 gattggaatg cctggcgaca ccattcgtta cgaaaatgat aaactctaca tcaatgacaa
    44341 agaaacggac gagccttatc tagcagacta tatcaaacgc ttcaaggatg acaaactcca
    44401 aagcacctac tcaggcaagg gctttgaagg aaataaagga actttcttta gaagtatcgc
    44461 tcaaaaagcc caagccttca cagttgatgt caactacaac accaacttta gctttactgt
    44521 tccagaagga gaataccttc tcctcggaga tgaccgcttg gtttcgagcg acagccgcca
    44581 cgtaggtacc ttcaaagcaa aagatatcac aggggaagct aaattccgct tctggccaat
    44641 cacccgtatc ggaacatttt aagagaccta agaggccgag aatcaccaat ctcagcctct
    44701 tcttctatcg tgagaagtga ttgtttattg acaaatactc aacgaaaatc aaagaacaaa
    44761 ctaggaagct agccgtaggc tgcttaaaac agtgttttga ggttgtggat agaactgacg
    44821 aagtcagctc aaaatactgt tttgaggttg cagatggaag ctgacgtggt ttgaagatat
    44881 tttcgaagag tataaaataa aaacaatccc aactctcacc tattcatgca aaggaatttt
    44941 atggaagttt atttttcagg aaccattgaa cggattattt ttgaaaatcc cagcaatttt
    45001 tatcgcatcc tcctcctaga aatcgacgat acggacgcag aggattttga tgattttgaa
    45061 atcattgtca caggaaccat ggctgatgta attgagggcg aagactatac tttttggggg
    45121 caaattgtcc agcactccaa gtatggagaa caactgcaaa tcagtcgtta tgatcgcgca
    45181 aaaccaacta gtaagggctt ggtcaagtac ttttcaagta gccatttcaa ggggattggt
    45241 ctcaagacag ctcagaaaat cgtggatacc tatggcgaaa ataccattga cgaaattttg
    45301 caacacccag aaaagttaga aggcatcgca ggactctctg ccaaaaatcg cgaggctttc
    45361 gtctccactc tccgtctcaa ctacggaacg gagatggttt tgtccaaact agccaactac
    45421 ggcattccca acaaactagc ctttcagatt caagactttt acaaggaaga aacccttgat
    45481 gtggttgaaa attatcccta ccagctggtt gaggatatca agggtttggg ctttaccatt
    45541 gctgaccaac tagctgagga actaggcatc gaaagtcagg ctcctgaacg cttccgcgcc
    45601 ggtctagttc acagtctttt tcaggcctgt atggaaacag gggacaccta tgttgaagca
    45661 cgggatttgc tggaacaaac ccttactctc cttgagtctt cccgtcccgt ggaactagac
    45721 cccagccaag ttgcccaaga gctctcctac ctgatcgaag aagacaaggt tcagcagatt
    45781 gataccaaga tctttgacaa cagcctcttt ttcgctgagg aaggcatccg cagtcacttg
    45841 gttcgtatcc ttgaaaaagg aaaacagaag agtcatgatt tagaaaccat tcaaaaacat
    45901 atcactacta tcgaggaaga gctgggaatt gagtatgata acattcaaaa acaggctatc
    45961 tgtgatgcta tccagaataa ggtctttatc ctgacaggtg ggcctggtac tggtaagaca
    46021 actgttatca atggaatcat cgctgtttat gccctgttag agggacttga cttcaggaag
    46081 aaaagcaatc tgcctattct tcttgctgct ccaactggtc gagctgctcg tcgcatgaat
    46141 gaattgacag gtttgcctag cgcgaccata catcgccact tgggaatgac aggtgacgat
    46201 gataccagtc atctggaaga ttacctagat gctgacttta tcatcgtgga tgaattctct
    46261 atggtagata cttggctggc caatcaactc ttctccaata tctcttctaa cagtaagatc
    46321 ctcatcgtag gtgacagtga tcagctacct tctgtcagtc ctggacaggt tctagcggat
    46381 ctgcttcata ttcctttgat tcctcagact cacttggaaa aaatttatcg acaaagcaaa
    46441 gaatcaacca tcgtcaccct agctagtcag attcgacagg gcatcttgcc agctgatttc
    46501 acccaaaaaa aagctgaccg ttcctacttt gaaattgcta gtggccatat tcctgccacc
    46561 attgaaaaaa tcttaggtgc cgccctcaga aatggtattc ctgcccgtga tatccaagtt
    46621 ctggctccta tgtaccgagg gacggcaggg attgatgcta tcaatcagct catgcaagac
    46681 ctgctcaatc ccccacaaaa agatcaactc agttttgaag ctcctcagtg ccactatcgt
    46741 aagggagaca aggtcattca tttggttaac gatgctgaaa tcaatgtctt taatggggat
    46801 ttaggagcta tcacagacct gattcctggt aaatacaccg aatcgaaaca agacgagatt
    46861 gtcattgatt ttgatggtaa tgaagtctct tacccccgta acgaatggta caagattcgc
    46921 ttggcctatg ccatgagtat tcataagtct cagggaagtg agttcccagt tgtcatccta
    46981 ccgattacta gtgctagccg acgtatgctg gagcgaaatc tcatctacac agccattaca
    47041 cgtgccaaaa gcaaactcat cttactaggc gaattacaag ccttcgacta tgctacccaa
    47101 cacatcggaa ctgcccgaaa aacctatctg attgaacgct tcagtgatct actggagaat
    47161 gttgaagaaa agcaacaagc tgtctctgaa acagtcacat caagtgcctc tgaacaatcc
    47221 tacatcctaa ccgaagaaaa ctgggacagc attccagcca tgattgggat tacagacaca
    47281 gacctcaaag agatttttgg aaaatagtgc atcagaaaaa ccaccaattc aggtgggttt
    47341 tctgtttatt aagattattt tactgttgct gtgcttgtaa tcaattcaac agcttttttg
    47401 atagtgatat catgtttcaa catgtcagct gaaagcaagt tttgaacttg tgcaacttcc
    47461 atgttgtagt ctgctgccaa ttgctcaact tctttttgga tttcttcttc tgaagcatca
    47521 aatccttcag ctttggcaac tgcttcgata acaaggttag tcttagtacg tgactcagct
    47581 tctgcttggt attggttgtg aaggtcttct tgagtagttc cagtaatttg gaagtacatg
    47641 tcagggttga tcccttgacg ttgcaagttc ccaaggaatt catttactga acggtgaact
    47701 tcttcgtgga tcatttcttc tggaagttct acgatttcag cattttctac agctgtatca
    47761 attgctgcac cttcaactgc atctttgtaa gcttcttctt tagcagcagc caattctttg
    47821 cggtattttt ctttcaagtc agcaagtgtt tcaacttctt catcaatgtc ttttgcaagt
    47881 tcatcgtcaa gagctggaac ttctttagct tttacttcgt ggatagttgt cacgaattta
    47941 gcttctttac ctgcaaggtc ttctgcttgg tagtcttctg ggaatgttac gataacatca
    48001 acggtttcgc cagctgagtg acctaccaat tggtcttcga aaccagggat gaattgacct
    48061 gaaccaagtc caagtgagaa gttttcacct tttccaccgt caaattcaac accgtcgata
    48121 gaaccaacga agtcgatcac aacagtgtcg ccgtcttcag cagcagcttc cttgataacc
    48181 aattcagcca ggttgttgcg ttcacgttcg atacgctctt cgacatcagc gtcagttact
    48241 tctttttcta catcaactga tacttcaagg tttttgtagt cacccaattt tacttcaggt
    48301 tttgtaacaa cttcagcagc gataacccag tcttgacctt tttccattga agttacgtca
    48361 atttttggtt gggcaaccac ttcaagacca gcctctttta cagctgcttc ataagcgttt
    48421 ggcaaaagag cgttcataac gtcttggtaa agtgattctt caccaaattt tttatcgaag
    48481 ataggacgtg gaaggtgacc tttacggaaa cctggaacat taagagattt cttcactgac
    48541 ttgaagacac ggtccaattc tggtttgatt tggtcttgag agatagtgaa agtcaagaca
    48601 ccacggtttg tttctttgtt ttcaaatgat acagacattc tgtcatttct ccttaaaatt
    48661 ttttaaatac agtctattat aacattttct ataaataaaa tctagactaa tgcagacaat
    48721 tatagacaac aagccttttt cctaactaaa acactcataa agtatagaca attttagact
    48781 actttggata tcttttggtt agtcattttc caaaactaat ttatctaatt tttaagttat
    48841 atttgacttc atcttctcag taacatgagt ataaacactt aaaatctttg tttcattagt
    48901 ataatctaca cgatccatta tcgctgttat aggtacttcc aattcagcaa gcaaacttat
    48961 atgcgaatat ctaaaaacat gagcagtcaa tacaaaatca tctttcttaa tttcactttt
    49021 cctaaacctg tttttcaaaa agtaattgaa acaagttatc attaagggag aaccattatt
    49081 tgtaaatata taatcacctt cttctaaaag aagatattct tttaaaattt ctaacactct
    49141 atcactaata ccaattactc tatatgaagc taaacttttc ggactatcca aaaacacttc
    49201 gttattggac gattacatta tagtaaaacg aaataagaac aggacaaatc gatcaggaca
    49261 gtcaaatcaa tttctaacaa tgttttagaa gtagaggtgt actattatag tttcaatcta
    49321 ctatacaaga cgaaattgaa gaaatctttc cattataaaa cgcatattat caaggttttt
    49381 aaacacctaa taatatgcgt tttttcctat tttaaagact tttatccacc tattatacaa
    49441 agttaagtat ccatcacagt ttacaattag ccttcattac ctaacccatt caccatcctt
    49501 caagagagta acctttaaga accgaataaa taaatggcaa atttcgttca tttaatttaa
    49561 ctgcactgtt aatttgatta gctccatctc ctaaagtatg cactcctact acacggtgac
    49621 tagcatcata aactgtagat ccactagacc cctctaaagt atcaacttgg taatccaaga
    49681 acatgccatc atcacttaaa acttgttttt tatctgtata catttgatga actttaaaat
    49741 tatatgatgg atagcctgtg atagtcacag ttattcctgt caaatttttt tgactagtag
    49801 gaagacccaa agtccctaat tttgcaccaa tgggctcttc tagaattaat aaagccaagt
    49861 catattccct tgcatcctta gaatttaaat ttctaaattc cttcaaataa cgaacttcct
    49921 ttactttgat ctttccaaat ggttcttgac ttggactaac agtcggaaga acataaatat
    49981 catccgcttc tttcccatag tcatgtctgt agtagttgtg agccgctgta attaacacat
    50041 tatctttaat aaaattcgca cttcccctcc cttctacatt cattccatcg gctactccat
    50101 aatacttaga taaaaccata gctgaagtcg aatacggata ctgtaaagta ttatcaattt
    50161 taatcaaatc atcattaccg ataatacttc tgattgcttt tggtagtatg aaccatatgt
    50221 tggtgaaatc tcagataatg aagaatcatt agatcctgga cctttttcta gtgtctcact
    50281 tacctcatat tcttcacccg tactagaaat aacactcaaa gcagatactg tcgataactg
    50341 gctagccaat aaagtactcg caataattga aatacccaat tttttataaa cagttttctt
    50401 cattattgta tcctcctaat gtaattatag cgtactattc taaatttctt aatctactat
    50461 agaatcaaga aatctaccac cttctttaaa taccctccat tatcacataa acaggtaaac
    50521 ttttcaatta atgactgcgc ttttcaatca cgctagaggt acttacttgc ttctttgata
    50581 ctaagttcag ccattctttc cttgtttttc tcaataaagc atgttaccca agtgggattc
    50641 gttttggagt agtctcgcag agtccagcca atggctttat tgataaaaaa ttctgtttgg
    50701 ttcaagttat gaagtagaat cttttccatt aattgagtat tggtcttctc ttttcttaac
    50761 aactggtggt caatagcgac acgtctcagc cagatattat ctgataggct ccattttata
    50821 ctcaatgaaa atcaaagagc aaactaggaa gctatctgca acctcaaaac actgttttga
    50881 ggttgcagat agagctgacg tggtttgaag agattttcga agagtattaa gattatttct
    50941 tctagttcag ggtgttcata caccaaactc cctactactc gatctaggat atctaccgtg
    51001 tcccaccagg attttgtcac gactaactgc tctagcttag gcaaatcggt ttcctttaga
    51061 taagactgca ttgctttcaa atagttagca gccacatatt ggtattttct aggctccttt
    51121 tcccagcaag tgtctgcaaa atcccaatcg ataatctttg tttttttcgc ttctggtaaa
    51181 tatttttata gagtttattt ctttcaggca ccgcaatacc tagaaaagaa aattgatggc
    51241 gcatataggc ttccatgggc cttgcttttt tagagtcttt tgctgcttct agctcctcaa
    51301 gtaaatctgc taaactcatc taaaactcct cttgccccac caaatggtgc tgaaaggcat
    51361 agacagccgc ctgggtacga tcgctgactt caagtttggc aagaatattg gacacgtggg
    51421 tcttgaccgt cttgagagag ataaagaggt catctgcgat gcgctgattt tcgtagccct
    51481 tggcgatgag ttggagaaca tctcgctcac gcgcagtcaa ttcttcatga agttccatat
    51541 gattgcggtg gtattcaacc ttcttgctaa cctcttgctc aatggccagc tcgccagcag
    51601 ctaccttact gacggcatga agcaattcat ctgcactaga agtcttgagc atatagcctt
    51661 tggcaccagc atctaagact ggcatgattt tttcattgtc caaataagag gtcacaatca
    51721 aaatcttggc ttcaggccat tctttaagga ttgctaaggt cgcgtcaatc ccattcatct
    51781 caggcatgac aatatccatg acaatgacat ctggacgcag ttccaaggcc aagtcaatcc
    51841 cttgagaccc gttggacgcc tcacccacaa cttctacatc gtcttggagg tcaaagtagc
    51901 ttttcaagcc caaacggacc atttcatggt catctactag taaaattttc atctttactc
    51961 ctttatcatt ccttatctaa caggggaata cggatatcaa ctgccagccc ttgcttggga
    52021 gctgttaata actgaaccgt ccctgccata tcttcaaccc gctccttgat atttcgcagt
    52081 ccataactca agtcgtctaa gcttcctaac cggaaaccaa tcccattgtc caccaccttc
    52141 agttgcaatt caacatctgt ctgatagagg tagacatcta ggcaagatgc ctgggcatgg
    52201 cggagggtat tgctaatcaa ctcttgcagg atacggaaga tatgctcctc gattttctta
    52261 ggcaatttcg tcatattctg cttgagacta accctaagat cactcttgtc ctcaagctct
    52321 tttaagagaa tctgaatccc ttctatcaag ctcttctgct ccagttcaac tggtcgcaaa
    52381 tgcaagagca aaacccgcaa atccttctgg gcagtttcta aaatagctgt gacactctgc
    52441 aactgggtct gcatcttttc tctatccaat ttcaaagcct gctgactgat acccgataaa
    52501 ataatgtggg ccgcaaacaa ctcctgactg actgtatcgt gcaaatcccg agcaattcgc
    52561 ttccgttcct tctcgataat ttcctcttcc tgatcaaggc tatgattttc agctttttga
    52621 agagcctctg tcaaaaggtt aagtttacct gataaggact tgaaactggc atccaaatct
    52681 ggatctacaa cctgaactac ttcttgccct gccaataaac gcttgagatt agcctgcatt
    52741 tttcttagag aaagctcttc gatccctcgc caaaacaggg ctaagagaca ggtcatggac
    52801 atgctgaaaa ccaacaataa aaagacaaat ttttctgttt tttcgacatc gtacaaaaag
    52861 atagaccagt caaaatcaag tatttccagc aagctgtggg agaaaaaaaa gacaaatagg
    52921 aaggaggtga gagcaataat gacataggct tgttttttca tcctctaacc acctccacat
    52981 caccaatcat agtggtcaag aaaatcttga cactcttgtt actcttgaga tagtcttttg
    53041 tttcttgatg atagtgttca ttgcggaggg ctcgcttggg ctggttgaaa aaagtcaaat
    53101 ccccatagag acagttaacg ctgagactga cttccacatc tacaggtacg atgattttgg
    53161 tcgttcctac catctttctg aggataatga cattgtcatg attggttaag atgactctct
    53221 ccagatgaat agtgtccttg cccatgaagc gaaagagatt gatatcatca aattggcaag
    53281 tctggtagct tgaaaaatga tgaagatttc caaaccaacg atttttctcc ttcttaaccg
    53341 tcacaacctc ttcaaaaacc aaattggtct gctctttttc ctggttcatc atcgggtaaa
    53401 gaagaaagag actatagata accgcaacaa aaatagctag aatcacaaaa ggattgagca
    53461 taacgatgaa aaagaagaga atggttgccg ctactaaaag aagattattc ccctctttac
    53521 cagtatagta gcgaatcaaa agcaaaaaga ggaatagtat cagcagaaaa cgcgaaaaat
    53581 gctctgatac catcaaaatc agagctcctg tcagaagaca ggcttcgata aataaaaaga
    53641 ttttaaattt tctcataggt tcatcctctc ccttctattt tatcacaatt caaaaaagtc
    53701 acctcagtct gaggatggaa aaaaaggcgc tggttacgcc tttttcatct gatcctttgc
    53761 ttcttttaat tttccataaa gaagatagtc tactttttgt agatctgcta tggtggcaca
    53821 gttaagggaa cacataatca agcgtagatc tgctttccag ccttggacaa tgccaatcac
    53881 ttcttcaact gtgtaggttt caaccaattc cagaacggtt cgtgacaatc ccacagcctt
    53941 agcaccaaaa accaagcact taatcatatc cagcggattc cgaacccctc cactaaccaa
    54001 gagttcgacc ttatctttcc attcttgggc attgagaagg gcctgcatgg tagactgacc
    54061 ccattgattg aggtaatcac gctggccact acgacggttt tcgatatagg caaagctggt
    54121 gccaccacga cccgataggt ccactgtacg aacaccgaat tcataggctc tttcgattgt
    54181 cttggcatcc attccaaagc ccacttcctt gaggacaata ggaacgggaa tttgcttgct
    54241 ataatctgct agatgcgatt gccagcttct aaacttcctt tctccctcgg gcatgagtaa
    54301 ttcctgcatg acattgacat gcacttgcaa tagaacagga ttcatctctt ctacagtctg
    54361 aagtcctaac tcgacaggtt tgtccaatcc aatattggtt ccaaggagga gattgggatg
    54421 actagacttg acagaaaaag aatcatccgt tggatttttg agggctgcgc tataagaacc
    54481 cgttacaaat aaaataccac aggattccgc cacctgagcc agcttttgat tgatttctct
    54541 tcccttatta cttccaccag tcatggcatt gatataaaaa ggaaagtccc actttcgacc
    54601 agcaaactct gtcgaaagat cgatttcatc cagattgtaa agaggcaagg aagaatgaat
    54661 cagctccacc tcatcaaagc tattatagga acttttctgc tcaagggcat agaggatatg
    54721 ctcgtcctta cgatttgtcg tcatgtccta tcctttcttg atataagagc tcaatcccca
    54781 gatcggccca acgatttttt aaggttttgg ttgattgcgc atcaaaactc agggcgatgc
    54841 cacagtcacc accaccagca ccactactct tggcaacggc ctgcaaatct tgactggctt
    54901 ctttcaactg tctaagcaaa ggcgtgtaaa tatctgtact caagccttct aaaagcttgc
    54961 tggctacttc tacttgctcg ataatctttt ctgatttccc ctgttccaag gcttcgacca
    55021 aagaaaccac cgtttctttt gaggaactta aaaaattttg attgatattt tgcttgattt
    55081 gctggaccat gtgactcgat acagccactt ccttggtcca tcccactaag aaatcacatt
    55141 ctaaagttgg tttcacttgt gaaattgaaa agccccaatc acgctccaga actgtcgcca
    55201 agttttcttc ttctaaccaa gcagccacct tctggcgatc aaatgactgg tagagaacca
    55261 aatcctctgc cacaatacag gcaaggtcgc ccatggaacc attgtctcct cgcttgagca
    55321 agacagcgct agtcagcttg aacaagagct cctgatcaac agaaacatca tacagagcca
    55381 gtaaagcctt gacaaccaag acaacgacgc tgccactaga acctagacca aactttttcc
    55441 cttctcgttc cattttgcca cagatttcta gggaaaaaga tcttaaattc tgaccgcgaa
    55501 cagcgaggaa gtctcccatc aaagcaatcg tttcttgaat caagctgtag tcaggattgg
    55561 gcgttaagtc cactgcgaaa tcaaacatat ctgaatagat acggtagctg tcagaaaaag
    55621 caatctcagc cctcatatag atgggaatat cctttatcaa agctaactgc cctggctcta
    55681 aaatagcata ttcacctgcc caatagagtt ttccgcaagt tttaacagca atcatcttga
    55741 ctcaaatcct ttgtttttga cacaatcaag cgataacgct gaccgaaaat ttctgacaaa
    55801 tgctccaagt ctttctcctg acaaaagacc ttaacattgg gaccagcatc catggtaaag
    55861 tagcaggcct ctcctttctc acgaagctgg cgaacaaagt ccatagcctc ataagaggca
    55921 tccgtcagat aagaaaaggc tggactagca gtctttgtcg tagcatgcat agccagggca
    55981 tttttctccg ttaattctcc aatcttggca aaatcatttt ccttgagata aatcagcata
    56041 tcctgatagt ccttctcaga ctgacgaacc cagtcgtcaa aagtcgtcga ggtttccaca
    56101 caaagtttca tcccgtcacg gctagagatt ggttttttct tgtcctctag caccaacata
    56161 atcatagcta gtttcaagtc tgtctctaca gagtaaattt ctccactatc cttatcccag
    56221 gctcctagcg gtccataaaa actccgagaa gaagagcctg aggcaaactt ggcttcctgc
    56281 gctaactgac ttctatccaa tccaagcttg aaataagcat tacaagcctt gaccagggcg
    56341 gacaaaccac tagaacttga ggacaggccc gctgcagtag gcatattgtt ttgagtatcg
    56401 atacggacaa agccctcacc agctggacga taacggtcaa taatcttact catcttggca
    56461 tgctcgacct cattttgtag ctgaccattg atgtaaaatt cgtcagctat tacattggct
    56521 ggtaaaggcg acaaggtcgt ctctgtatac atattttcca aagttagaga aatactgcta
    56581 gtagcaggca ccatctcttt ttcttttttc tttccccaat atttgataat agcaatattt
    56641 gcgtaggaac gtactgtcac aggctctcta tccatgtctg aacagctcct ttctcttcta
    56701 atctttctgc tagttcttgt gcgtgtgtca aattggttac caaggctatg atacaacctc
    56761 ctagcccacc accgctcatc ttggcaccca gagcaccatg gctaagagtc gtttcaacca
    56821 aaaagtctgc ctcagggcta ctgactccaa tttcttttaa atgtaaatgc gcttgactga
    56881 ggatttgtcc cagtccttca gcatcttttt gtgaaatcgc aacttctgct tgctgggtta
    56941 attctcccaa ggcatgcaaa aacggtaggg catccttgcc cttattttga accacttgga
    57001 tggcttcacg agtatgacca taaacacccg tatcggcaat caccaaatag gcggataaat
    57061 ccatctcaag ttctgtaaat cctacgttct tgataaagcg aataggttgg tcactgagac
    57121 aggtcttagc atccaaacca ctaggattca tatgggcaat catctcagct cgattgacca
    57181 agatttctag tacatcatga ggcagatcag cctgatagta gtcaaatacc gcacgaatgg
    57241 ccgctatgct gatagccgct gacgaaccca tcccccgttt ctcagggata gccgagtcaa
    57301 tctcacaacg aatgcaggct tctgtgatat ccaaatactc cagtgaggca taaaccgcca
    57361 tggacaaggt atcctcctca taaaggcgcc aaggactctc tgcaggaact accttacagg
    57421 tcacctccac ctccaaaaga ggcagggaaa tggcaggata accgtaaacg accgcatgtt
    57481 cccctattaa aattatctta ctatgtgcct gaccgacacc aacttttttt gtcatttttt
    57541 ccttttacta gacgaaaaaa cgtcttattt ttcatacaag tattaattct ttcctatcta
    57601 ttttattata ttttcacaaa aaaagcgatt gtttccattc acaatcgctt ctttcattat
    57661 tgaacccatt cgccattata gttgacagaa tagccatcta cggtcgtatt cactgccaag
    57721 gcacctgagc tataagcgta gtaccatctg ccattgacct ggaaccaacc tgtcgtcata
    57781 gaacgacgaa agaaactcca taccgttaag taaagaggaa agtcgtgagg gatcatgcgc
    57841 cattgacaac ctgttttagt gacgtacaaa gtctcattaa caagtactcg tttcggccat
    57901 ttataggtgc ggtgtttgga gaaatagggt tcaatcttag cccattcttg atcgtttaaa
    57961 tcagtatcat atgctttgcg tgtcataact ctagtttaac attttttgtg aatacaagtt
    58021 ctaaataatc gaccacgaaa atttcttaag tggaaaacgc cttatgaagt atgctacggg
    58081 aaacttatgc acttaatttg acaattcaag atgtaaaaat atatactata gtagattgaa
    58141 actagaatag tacacctcta cttctaaaac atttttagaa atcgatttga ctgtcctgat
    58201 cgatttgtcc tgttattatt ttattttact ataatatttg acaagttatc ctaaaagtat
    58261 tattatgttg ttgtgttata gattgattga atctaactaa aggatcctat tcaattacta
    58321 gaactatcac atactcaagg tcagctcaca gatgagcaac tattttggtt acaatgtcta
    58381 ctaaatttaa gtcaaacaaa taatttagtc aaaattaaaa aaatagagga acataaatat
    58441 gattacaaaa cagaatgtaa tagtgttcta cgatttttac tagataaaac tgtaaattct
    58501 gaaggaagga tcacttcttc aacagaattt ggaaatttcg taagtaattt atcattccaa
    58561 cacggaatag ctggactact gtttcctcta aataaattgt accccccaga actggattct
    58621 aaaatactct ctatcatcaa gaaggcagtg acaattagaa cgacacacat atgaatatca
    58681 atactcactg ctatttggtg atgcaggcta tctatggtta ctcctacatt tattttctat
    58741 cagtaaaaat caatactatc tacaattagc aaacgtcacc gctaagaaat taatagagaa
    58801 ttatgatact ctagaagaaa tagactttgc attgggaaaa tctggtgtcc tattatcatt
    58861 aataaaatac tatcaattta ccaatgacaa tactcttaaa actttcatcc acaatagtat
    58921 atggggaaat ttatcattat ttcctacaaa gagatacagc caaagaaagc attttagact
    58981 atagctttgc tcatggatat tgtgaaattg catatgcttt atttgcctat tctaaagtct
    59041 tagaaccttc tatgttctat aatgatctcc atacattcca tgctgaatta aaaaaattat
    59101 tagaaaaagt tacttctaat actgaaaatt taggaaattt acaactttct tggtgcgaag
    59161 gaatttccgg aataatctta tatctttgta tgtacgattg tgacggaaac aaagatatta
    59221 ttagtaaata tcaagaattt gtttttaacc atcatctaaa aatgatgaca ggatattgcc
    59281 acggaataac tagcttacta caaaccactg tctacaatca aaacaaatta ctgatgaaaa
    59341 aaatccaaca ggtaatttta gcatgttctg aacgagatga tcacggttta ctgatgtttc
    59401 aaggagatag tggtaaagca gatttgtttg acttcggaat aggaagcagg gggtatattg
    59461 gtgtctatta aataataaat tcccattcga tgtgcaaaca taaggagaaa tgtatgaaat
    59521 tattttggac aaacaacata tatagacagt tgctgctaaa cagctgtttt tcatcattcg
    59581 gcgacagtat tttctacctc gccattatca attatgtggc tcagtacaat ttcgctccgc
    59641 tagcgatttt actgatttcc atttcagaga tggttcccct actatcgcaa ctctttctcg
    59701 ggattctagg agattttcaa gaaaatagag tcaaacacgc actctgtatt gccaaaatca
    59761 aaatcctgct ctacgctatt ttgacagtat ttctcgtctt gtcgcccttt tcattagttt
    59821 cagtcattat gattgtcatc atcaacctca tctctgacac cttgagctac ctgtctgcct
    59881 acatgatgaa cgccctctac atcagtgtaa ttaaggatga cctgcatgat gccatggggt
    59941 tcaggcagtc tctgatgagg gttgtccaca ttgtcgccaa tctggctggc gcattcctta
    60001 tcaatgttat aagtattcaa actatttccc ttatcaacac tctgactttt gtcattgcct
    60061 ttttgggcct gtatgttatt cgacatacct tgtatgaggt tgaaaaaagg attgaaatgt
    60121 cacatacagc actgagtttt aagaaatatt ttcaacatct taaacagtcg ctggctgtgc
    60181 tcctgaggtt aaaagatacc gtcatactac tgtttctgac gaccagtatg attgccatct
    60241 tggatgtgtc ccctcggctg attgccctcc gcttcatcca acagacacta gcacaactga
    60301 gcattgggca actcttcgcc ctgctctcca tcatcatgtc ttgtggagct atccttggca
    60361 atatgaccag cagtaatcta tttaaaaata tccgtttcac gcacctcttg gttttctgtg
    60421 agatttccct attggctcta ataactagta tcctttgtca agcctatatc gtaattttcg
    60481 tgaccagttt catcagttct acgattatcg gcattctcag ccctcgccta caagcagctg
    60541 tctttgccca tatccccagt gacaagatgg ggacggtggg ctctgctctg agcacagtag
    60601 acattctcgc cccgtccctg ctctccctat tagccctatc catagcatcg ggcgtttcgg
    60661 tgcagttagc attgatattt ttgtatctta ttttgattgc tcttatcttt tgtcaatggt
    60721 tagtcaagtt caacactcat aactaacgaa aaagcatgtg tagatttcac atgcttttaa
    60781 tctccccaat cgtcaggtca agtacaacaa agtcacttct ttgattaagc gagtgttcta
    60841 atataattat aagcgccctg tcattaccga acccattcgc cattatagtt gacagaatag
    60901 ccatctacgg tcgtattcac tgccaaagca cctgagctat aagcatagta ccagttgcca
    60961 ttgacctgga accaacctgt cttcatgtct ccattacctg catttaggta gtaccaagtt
    61021 gaaccatctt gataccaacc agttgccata gctcctgatg aacggagata gtaccatttg
    61081 ttcccaaggt tttgccaacc tgttttcata tcgccatttg gctggtctaa ataataccaa
    61141 gtggtacctt cctgatacca gccagtggcc attgctcctg aggaacggag gtagtaccat
    61201 ggagcaggtt tgcttctatc aatgtcaata gtaacatgaa aatcttgagt ccaaccctta
    61261 gcaacttcac caattggtag tggattgtaa gaatcatcac caaaatttcc tagcttattt
    61321 aaataatacc aattgccgtc ttcataaatc cagcctgtct ttacagcata attattatca
    61381 aaataataag ttctcttttc agcagataga ggatattgtt caccgtatac ttttcctgta
    61441 ttttcagacg tttttgcctc tagtacttgt ttatctgttt gttctagcaa agcaccatct
    61501 tgtccaaaat agtaccactt ctcctgaagg ccaatttcga agactggacg attatcaaat
    61561 aaatcatcac gataacctgt tccaggaatt tctaagtatt gccaaccgac aaccatctct
    61621 ccaatatcac caaaatagta agttttaccg tctattttat gccaatagat tgctttatga
    61681 tcatctttta cataatattt tctattatcc ttatcaacaa atcggccacc tgtggtattc
    61741 gcaaataccg tatttgtagc tagcaaacca aagaaaaaga ctgctagtag aacttgcatc
    61801 atttttttca aaagtttcat ttatatatcc tcctaaaacg attgtagcaa agacacgact
    61861 gcatgtcaat atataaaaac tcctcaaaaa agcagttaca caactgcaac tgcttttcta
    61921 ttcttgcatg gtgtaaccaa caccacgcac ggttttaatg tagctttttt gtcctttaac
    61981 atcaagcttg ctccgtagat agcggatata gacatctacg atatttgtct cggtcgcact
    62041 ttcatacttc caaacacttt ccaacaattg ctcacgagtc aatactttct tgcttcccat
    62101 aagtgtcgcc aaaaggtcat actcacggcg ggtcagagca atcatctctt caccacgata
    62161 aaccgtgtga tgttcaacat ctatcctaag attgcggtag gtccttggaa ctttcatcag
    62221 actgcagtgt tgatcaatga agtcccgacc tcggaagatc gccgaaatac gcgctaccag
    62281 attttcgata aagactggct tatagatgta tgaaactgca aaacgctgaa caacttccag
    62341 ctcttcttgc aagtcttccc aatgatctaa aatcatgatg actgaggcag gtttagttcg
    62401 actcaatttt tctgcaaaat cctgagccat catatctccc agattaacgt tcaataaaat
    62461 caaatcatag tctgtctgaa gagccatgga aagggctttt tgcccctcct ctaccagatc
    62521 aacccgatac tgctctttct ggagttccaa acttaaaaaa tgagctagat ttcgttcttt
    62581 ctcaagtaat aaaatccgtt tccccatggc tgacctactt atttttcgtc ataccaagag
    62641 tagtggaagg ttccttcttt gtctttacgt tggtaagtgt gagcaccaaa gtagtcacgt
    62701 tgtgcttgga tcaagttagc cggaaggtca gctgaacggt agctatcaaa gtaagtaata
    62761 gctgctgaga aagttggcac tggcacacca gcttgaaccg caagagctac gatatcacgc
    62821 actgcttgtt gatacttagc agtaacatcc aagaagtact cgtccaaaag aaggttggca
    62881 agatctgcat cgcggttgta agcatctgta atcttttgca agaaacgaga acggatgata
    62941 cagccatcac gccagataga tgcgatatct gcaaatggca agttccagtt gttttcttta
    63001 gaggctacac gcaattgagc aaatccttgt gcgtatgaaa tgatttttga gaagtaaagg
    63061 gcttgacgga ttttttcaat caattcagcc ttgtctcctt caaagttgaa ggcagctggt
    63121 tttggaagca ccttgctagc atgtacacgt tcttctttgt aagttgaaat gtagcgtgca
    63181 aacactgact cagtaatcag tgacaatggt acaccaaggt caagagatga ttggctcgtc
    63241 catttaccag ttcccttgtt acctgcagca tcaaggatgt agtctacgat tggtccatct
    63301 tggtcttcat cgtctttacg gctcaagata tcagctgtga tttcgatcaa gtagctatcc
    63361 aattcaccct tgttccactc agtaaagatt tcagccatat cctctgcaga aaggcctagc
    63421 aagtgttgca tcaagtcata gctttctgcg atcaattgca tatcaccgta ctcgataccg
    63481 ttgtgaacca ttttcacata gtgaccagct ccatcaggac cgatataagt cacacatggt
    63541 ttgccatctt ctggtgcttt agctgagatt tcttcaagaa catccgaaac caattcgtag
    63601 gcctcttttt gtccaccagg catgatagaa ggaccttcaa gggcaccttt ttcaccacca
    63661 gaaactccag taccgataaa gttgatacct gagtttgcca attcttcatt acgacggatg
    63721 gtatctttgt agaaagtgtt tcctccgtca atcaagatat cacctttgtc aaggtgtgga
    63781 agaagggctt ggatagtagc atctgtacca ggtccagctt gaaccatcag catgatacga
    63841 cgaggttttt cgattgagtt tacaaaactt tcaacgtcat agcttggtac aaaattcttt
    63901 tcaggatggc aagcaatcac atcttccgtt ttttctttac tacggttgta gatagcaact
    63961 gtgtaaccac gtgattcaat attaagggca aggttacgac ccattacggc catacctacg
    64021 acaccaaagt tagcttttgt catttgacac tcctcttgtt tcatttgttt tattttatca
    64081 tttttacttt tgaaaagaaa gaattttgta acgactgctt agtagtccaa gtcatccgca
    64141 tgaccagcgc catttccgac aaagtagcct gtcttacagt taagggtaaa gagataggtt
    64201 ccatctggct tatagaggtt gtaataacca ttgccgttaa cgatattgac acgttcaagg
    64261 atatattggt ctccagtgat atagccacgt gaacgtgaag ttgctagaat ttgttccaaa
    64321 acaccatccg caaaatccca ggcagagtta ttactatcat caatagcaga ctgattatag
    64381 gcaacacgac tggcacttct ttgaacagca acccctgcac tcgagagacc catattgact
    64441 tcactgcgac tacttctagt ctcatttgaa ctacttggtt ttggctcact agtcgtattt
    64501 gaacttgctt gacttgaact tgagctgcta gtttgacttg aacttgagct agaagtactt
    64561 gtttgctggc tcttaccaag actgatagcc ttatctagca ctttatcaag ctccgtattt
    64621 ccagttttaa tatccgtaaa tttagcatcc gatttggctt tggcattggt atccaacaca
    64681 ccatccacaa tagctggttt ttcaaattgt gcattgacat cttgaatggc cttgatttgc
    64741 gttactagac tatcatattt agatttggca agcgtatgtt cacgactacc ttccagctta
    64801 tcaagtaaag tcttgagttg actcagttta tcaaactggc tatttttcaa agccgtttta
    64861 ttgctatttg tgtaaaaggc gtcataaagt gtattaaaat catccacatc cgattgattg
    64921 gctgtagttg attgagaagt ttcaatttcc ttggtcgaac gagccacttg acgatagaca
    64981 taataagcac tgacacaaat aattactgat acaagcgcca aaacggtcaa aataaagcct
    65041 tttttacttt tcttttctga gtcctcttga tccagacgag aaaggttttg ctcctcttcc
    65101 acttcttcag tcatttctgt tggattttca tcatctagca atagaggatc caagccttgc
    65161 tcctcatcgt ccagaggcaa gggtagtaag atgtcttcag aagatggaac ttcctccgaa
    65221 gaagcttctg acttctctac agcctcacgc atctcttgaa ttaaatcatc cagactctga
    65281 gtttcaacga actcctcttt tttgtattga cgagtcgcaa acttatccgc ctcaatttca
    65341 tctctgtgtt gcttaacata cttgtccaaa atggaatcct caggcaagac tcctgcttcc
    65401 acttcttcat ttttacgaat agcttgacca actgttagct cttttgcttc atcaaaatca
    65461 aattgcggtt cttgaccttc ttttttatga cgatttcgtc tttttttact catgagtatc
    65521 cctttctatt ttacctcttg ccgtttgaca cgctgaccaa aatattgata tagatccact
    65581 ttcaaggttc cgttgtataa cttacgcttc ttatctgctt ggctaccata cttgctttca
    65641 aaagcttcat cactagtcag gataaatttg ctccaagttt tcagcggtgc aaatacttgc
    65701 cccatctcag catagagctt ggtcactcct gcatcatctg acaaacgttc accataaggc
    65761 ggattggaaa tgattactcc attgatttta tcggaacgta aatcctgcac gcgcatctgc
    65821 ttaaaagtaa tatctcctgc aacaccagct gcctgagcat tggccttagc aatttccacc
    65881 atgcgagcat caatatcaca gcccatgata tccaactcaa gcttacgttc tactttttta
    65941 gccgcttctg tgcgcacttc ttgaatcaag cgatcgctga tccagttcca ttcctcaaat
    66001 gcaaaagagc gacgaagacc tggcgccatc tttctagcaa tcataactgc ctcaatacag
    66061 aaagtccccg aaccacaggt cggatcaatc aaaggcttgt ctggatacca gttagaaagt
    66121 tgtaaaatgg ctgctgccat attttccttg ataggagcgc cacctttttc ggtacgataa
    66181 ccacgtttaa agaggctaga cccggtcgta tcaatcatga cagttgccac atctttgaga
    66241 atagagacct caatcttaaa ctctgggcca ttctccatca gaggaacccc ttctgggcga
    66301 gcatagtgtt tctgcaattt cttgacaaca gctttcttag aaatagcctg aacactgggc
    66361 tcattgtgaa gtttggactt aacacattta gcttttgaaa tcggtaaccg agctccaagt
    66421 ggtaaataat tttcccaatc taaagcgaaa actccctgaa atagctcttc aaaagtctta
    66481 gctgggaacg ttcctacgat aattttgata cgatctgctg cccgaagcca aaggttggtt
    66541 tcgataatag ctctcacgtc tccttgaaaa cgaacacgtc cattttcaac ctgacaatcg
    66601 tagcccaact ctcgcacttc acgaccaacg acagcctcaa gccctgctgc cacagttgca
    66661 attaaattaa attctttttt catgttacag tcttgcaaga cctttctata tgtccacttt
    66721 aaaaaatgag gttgagaaaa tttctcagcc ccaacctata tgcaattttc tataagccat
    66781 gttttgttcc agaagtgact aggaccactt ccttcgataa tcatctgtct accactaaca
    66841 gctctagctg atagcagtca gaatactacg ttcgtttccg catactccat gccccgacca
    66901 aaatttgggt tgctagcttg aggggtttac cgcgttccac tctctctgtt tccagaaaga
    66961 ctccgtcact gtggcacttt caagcctact ctggcctatc caaggactta gccatttcaa
    67021 ctgccgtaac gatttctcgt ccctaggctt atggtttcgc ctagcacaaa cactacaggc
    67081 atcacagcct gtgctagcat ggactttcct catgagaagc aattctcctc acgcgattat
    67141 ccaaaaattg cacatctcaa ataactactt aaaaatctga gttatctaaa atttgtttac
    67201 caaaaacttc tttttccaat ctattcaggc gtttcaaaat atcaaaattc gtcatagaac
    67261 ttgtaattgc cgcttcaagg ggttctgctt gaactggtga aggtttcggt ttacgagtta
    67321 attcttcctt caaatccgca atttcctgac gaagtgactt gaccaaggca gcataggttt
    67381 catagtcctt gatgacatcg tctaaaaact cgtcaacttc tactttatta tagccacgga
    67441 cttcacgtcc aaactcttgt tcaaaaatat ctttcgctga aaaaataata cttgccatgt
    67501 ctctctccat tctcgcttgc tagtattatt atataaaaaa aggcaaacaa aaatcaaggt
    67561 caaagcttca attttcggaa aaattttcag caagttcatt taattgatca aatgttaatc
    67621 tctttataaa atagtcctct tgatttttca tcttttggta aaaataagct agttttgttt
    67681 cattttcttc atcataaaaa agataggaac tagtcgtgtt ttccagcaaa aactgctggt
    67741 aatctcttaa ctgccccttg tgttcatagc gaggataagc atatttgaca aagtctacct
    67801 gcttaaagcg actcagtttc atctgattgc cttcattcca attttcccca tgggtttcaa
    67861 aagcaaaaat ggtggccaac tggaaaccgt attcggtttt catctcctga gcaacctcta
    67921 aaacccaata ttcaaaaccc aaactccctg taaacacaag ccaagacacc ccatctgctg
    67981 ccatagcctc taaatcttta cgtatcgctt ttttaatcaa tttaagacga ggatccttat
    68041 cagaaaataa acccaaatca aaagcagaat agcctaaaac caaagctgta gccattttta
    68101 accctttctg tgcaaattat ggtataataa agtgatgtta ttgtaccaat aaggagaatt
    68161 atgatcaact atccacataa agtttcatca caaaaaagac aaacatctct ttctcaaccc
    68221 aaaaatttcg caaatcgagg aatgtctttt gaaaagatga tcaatgctac caacgactac
    68281 tatttgtctc agggcttggc tgttatacat aagaaaccaa ctcctattca aatcgtacaa
    68341 gtggactatc cacaacgaag tcgtgccaag attgttgaag cctattttcg acaagcttca
    68401 acgacggact attctggcgt ttataatgga tattacatcg actttgaagt caaggaaaca
    68461 aaacaaaaac gtgcgattcc gatgaaaaat tttcatccac atcagattca gcatatggaa
    68521 caagtccttg cccaacaagg aatctgcttt gtccttcttc acttttcttc tcagcaagaa
    68581 acctacttat tgccggcatt cgatttgatt cgcttctatc atcaagataa gggacaaaaa
    68641 tcaatgccac ttgaatatat tcgagaatat ggatatgaaa tcaaggctgg tgccttccct
    68701 caaattcctt atctcaatgt tatcaaagaa catttattag gtggtaaaac aagatgaaca
    68761 aaccaacgat tctgcgccta atcaagtatc tgagcattag cttcttaagc ttggttatcg
    68821 cagccattgt cttaggcgga ggagtttttt tctactacgt tagcaaggct cctagcctat
    68881 ccgagagtaa actagttgca acaacttcta gtaaaatcta cgacaataaa aatcaactca
    68941 ttgctgactt gggttctgaa cgccgcgtca atgcccaagc taatgatatt cccacagatt
    69001 tggttaaagc aatcgtttct atcgaagacc atcgcttctt cgaccacagg gggattgata
    69061 ccatccgtat cctgggagct ttcttgcgca atctgcaaag caattccctc caaggtggat
    69121 caactctcac tcaacagttg attaagttga cttacttttc aacttcgact tccgaccaga
    69181 ctatttctcg taaggctcag gaagcttggt tagcgattca gttagaacaa aaagcaacca
    69241 agcaagaaat cttgacctac tatataaata aggtctacat gtctaatggg aactatggaa
    69301 tgcagacagc agctcaaaac tactatggta aagacctcaa taatttaagt ttacctcagt
    69361 tagccttgct ggctggaatg cctcaggcac caaaccaata tgacccctat tcacatccag
    69421 aagcagccca agaccgccga aacttggtct tatctgaaat gaaaaatcaa ggctacatct
    69481 ctgctgaaca gtatgagaaa gcagtcaata caccaattac tgatggacta caaagtctca
    69541 aatcagcaag taattaccct gcttacatgg ataattacct caaggaagtc atcaatcaag
    69601 ttgaagaaga aacaggctat aacctgctca caactgggat ggatgtctac acaaatgtag
    69661 accaagaagc tcaaaaacat ctgtgggata tttacaatac agacgaatac gttgcctatc
    69721 cagacgatga attgcaagtc gcttctacca ttgttgatgt ttctaacggt aaagtcattg
    69781 cccagctagg agcacgccat cagtcaagta atgtttcctt cggaattaac caagcagtag
    69841 aaacaaaccg cgactgggga tcaactatga aaccgatcac agactatgct cctgccttgg
    69901 agtacggtat ctacgattca actgctacta tcgttcacga tgagccctat aactaccctg
    69961 ggacaaatac ccctgtttat aactgggata ggggctactt tggcaacatc accttgcaat
    70021 acgccctgca acaatcgcga aacgtcccag ccgtggaaac tctaaacaag gtcggactca
    70081 accgcgccaa gactttccta aatggtctcg gaatcgacta cccaagtatt cactactcaa
    70141 atgccatttc aagtaacaca accgaatcag acaaaaaata tggagcaagt agtgaaaaga
    70201 tggctgctgc ttacgctgcc tttgcaaatg gtggaactta ctataaacca atgtatatcc
    70261 ataaagtcgt ctttagtgat gggagtgaaa aagagttctc taatgtcgga actcgtgcca
    70321 tgaaggaaac gacagcctat atgatgaccg acatgatgaa aacagtcttg acttatggaa
    70381 ctggacgaaa tgcctatctt gcttggctcc ctcaggctgg taaaacagga acctctaact
    70441 atacagacga ggaaattgaa aaccacatca agacctctca atttgtagca cctgatgaac
    70501 tatttgctgg ctatacgcgt aaatattcaa tggctgtatg gacaggctat tctaaccgtc
    70561 tgacaccact tgtaggcaat ggccttacgg tcgctgccaa agtttaccgc tctatgatga
    70621 cctacctgtc tgaaggaagc aatccagagg attggaatat accagagggg ctctacagaa
    70681 atggagaatt cgtatttaaa aatggtgctc gttctacgtg gagctcacct gctccacaac
    70741 aacccccatc aactgaaagt tcaagctcat catcagatag ttcaacttca cagtctagct
    70801 caaccactcc aagcacaaat aatagtacga ctaccaatcc taacaataat acgcaacaat
    70861 caaatacaac ccctgatcaa caaaatcaga atcctcaacc agcacaacca taacatttat
    70921 cacccagatt tttctgggtg attttgtcat agcactattg tatttatgtg cttaacaaaa
    70981 gcctgagaag atgtcttctc aggctttttc tgtactataa acctcattgg aaaagataga
    71041 gactgcttcc gtaatcttgt taagaggttt tactaaatac tagtctttct tcgtttttac
    71101 tacaaagaga gcagataggg ctagactaac acttgctagg aagagggctg tgtcagattg
    71161 actctcacct gttgctggca agatttgttc aggtgtttct ggtctagcta tttcttgctt
    71221 ataatctggc gtcttacctt gatcggaaac taaagagcta agtttaaact caggtttctc
    71281 tacagttgga gcatctggtt tcgtagcaga atcttttaat tggttgagat aatctgcaaa
    71341 gtattccacc attctttccg tcaagagatg gttatccgtc gcatatttca tgcttgcctg
    71401 aacgctagct acttcctctt gattgtcttt gtctgttaat ttctgagctt tagccaaagc
    71461 tgcttcatag cctgacaagt caagaggtgt ttctgctacc tgtggacgag taaagatgag
    71521 ttccgctgca gattggtatt tatcgccacc atctccgtaa gtcttagtac ctgtaaggac
    71581 aattttctta gccttaattg tcttaccaaa atcaatgtct tttggcttat tgttatctgg
    71641 ccaatcagtt gcagtaaagg tatgctcctt gccagactca tctgtcacaa caagtttcac
    71701 atcacgcaag ttaccatttg aacctgatcc acgtggaacg taacgaagtc cagtgatttc
    71761 agttggttct ttcaagacca tggttgcagg cttgcctaca tctccaccat tccaagatgt
    71821 atgccataaa ctagataagt ttccatcaaa ggcatttgca agaccttctt gagcctgagc
    71881 aggagctgta agacttgcaa agtcatctgc taccaaagcc gttttcttct gaaccaaagc
    71941 attcttcaag gcttcaatct tggcaatctc tgcacgcgct tcttccacac tgatatcatc
    72001 atcggcctga ctaaggttaa agaccgcctc tttcaaagca tccatagact ctttggtgta
    72061 gttagtcatg gcaaccgttg gcaagtagtt cttcagagca ttttctgtca acatcttacc
    72121 tgttagggta atttcttcga tttgaagatt atccatcatg aagtcgttat aaccacggaa
    72181 gttggcattt ccaccagaat caccacgagt attacttgca ttgccagttg agtagatacc
    72241 tacccaagta tcccctgttt ctgcacctgt cacaaggaag gttgccttct tggctttctt
    72301 agaatctgtc caagtatttg gcaattcatg catttccaag ttgcttgctt gagtgccacg
    72361 acgacctgac tggaattctc ccttaccgac tacaaaagca taggtattgt ctgaacctgc
    72421 ttcgtattca aaggttacac ggtaggtctt acctgcttca aaacggaagt tttgtgggat
    72481 ggtttggtaa accaagttac gacggctcac tagtccattt gtcttgagtg accaatttcc
    72541 ttcgataaca tcatcgactt tcttaccgtt ccaaccacgt tgtgtatatg gatcgtgttt
    72601 ttcagacaag tgagtgcggt tgtcttcgac accttcgaca ccacccacta caaatgggaa
    72661 gattccttga gctacatttt caaagtcttg cttgaaggtt ccttgacctg tatcgtgctt
    72721 gtctccatac atgcttgaat tgttttcaaa ggtacgaatt tcatcaaagt aagttgcttg
    72781 atcaccagct tcacgactca atgtcagagt aacatttgag acgtccgatc ctgttgtaaa
    72841 gaaggcgtac atgttttgga agtaacttgt atcgttaact gtagcattgt tacgacgtgt
    72901 attgtgggcg taggctttta catagttgag ggcgagagac ttattggtat aagtagtcac
    72961 ttctttttca ccagtattca cagtgatact tgccttggca ttactacggt tatcgacacc
    73021 gacataaacg gcatacttgg tatttggttt caagccagtt aatttctgag tgagactaac
    73081 tttttctttg tttccttgaa tacgaagcat atcgtttgcc ccttgagact tgacaatttc
    73141 tgccttagaa gcatcgcctg aaatggtcca atgtttcaag gtaccactgt taaatccttg
    73201 gtcatagatg tgcatgcctt cactccatga catttcagga ttggtttgtt ttgaacgata
    73261 gagaacgtat ggttgatttg ctagaagatc tagggtaatt ttaccatctt ttacagttag
    73321 ttcttgctct tctgtcttac cttggtcagt tagcttgtaa aggtaaacct tgctctttgc
    73381 ccaatcgctt ggaagggtcc aagttgttgc accggcctgc gtattgaagt agtacatctt
    73441 ttccttatca gtagaaagtt tcttaccatt tgcatcccag ttccaaggag tcaagtaagc
    73501 tgaaccatct tggatgacac gtccgttgag agttactgta cgttcgcgat attgtggact
    73561 attgacatca tttgacttac gagttacaac tactttatta ttgtcagcat ctaccaattc
    73621 cactcgcatt tctggagtcc atttataggt actaccgtta tcggtcatag tcaccggtgt
    73681 accattttcc catttactta cagtgaagtg ttggaagtac ttagtcatga cgtcatgggc
    73741 aaataagttg gttacatagc cattgtagtc acttcttccc tgccagcctt caaagtcttt
    73801 catgctgtag ccacctagca gtggatagtt ggctgcacca ccataacttc tgtagtcccc
    73861 aacccaagca tctttttggt ggttacggat aaagcgggtg atggcactgt tgataccttt
    73921 attggtgtag ccaccgtagg tcaagtcagc tgcccagtga tggaaggtag agtcgtactc
    73981 accaccatgg ccccactcga tcgcaaagcg ccagccttgt ttgttaattt ctttagcaag
    74041 aacgtgggta gcccaggcac cgttatcacc tgattgacca ttaccccaaa cgtccacata
    74101 gataaagtcg agaccgtcac caagtttttt cttcaaatct tcccaacgtg ccaaacgacc
    74161 atgagctagg tcataggcag catcaatgtt gataccttga tctagccagt tccaaccata
    74221 gctatagctt ccatctggat tcttacggag aattttttca ttgaagtatt tagactcagg
    74281 ataagtttct gaagcgttaa cgtggatacc tagatgagct ccatatttct tagccttctc
    74341 aattagggtc ttgaagtctt cgacaccacc gatacgctta ccaatatcag catagttcaa
    74401 gtgaccagag tcatggcctt cgctaccata tcctttaagg aaaacacctt gcccaagacc
    74461 atctgtgtgg agattgattt tcttgatacc atccaaggtc ataaggaatg gattttgtgc
    74521 ttgagaacca aagttcatcg cgatacggta agctgtgata tccttaactt tttcccaacc
    74581 ttgaggattg ttcataatgc tacgataagc aatggcacca tcttgccaat cgactttctt
    74641 gtctgcattg gcatcttcag tgataacaac cttagcactt ggaagttcct tcgtgtattc
    74701 tgggaaaaca atgcccttat aagctttttc ccattgccat tcagagctgt ggattcctac
    74761 atagttggca tttccgactg tttctttata agctgtcaaa cgagtccagt cattcgaacc
    74821 accaccatag ctattttgag agttactcca aacaccagca gcaagcttat ctgtagaaac
    74881 aaatccatac atgtaaccct tggctaggtc tttcattgga ttggttacat cgatatgatc
    74941 atctccgctg acatgcgtat tgtttgacat ggttgcccca tcaaacttag caccagtttg
    75001 atcactagaa acagagacta aagcattgcc gaggaaacta atagaagaaa gtagttttct
    75061 ttcgtcatca atcttttgac ctggagtgac ttgattgtgg ttgacaatct tggtcacatc
    75121 aaagtgcaat tgattgtcca caacttgcaa gcgtactgtc atttccgcat tgattaagtg
    75181 agcatcatcg cgaagcttca tcaagtactc tgctgttgtc tcattgattt tcttataagt
    75241 gacttcaggg gtgattcggt ggttattgat aaagacttgg ttgaactgtt gcacctgtcc
    75301 tggcaaagta tgtccattca agctgtattc cttgacacga gggaaggctt ggtcaatcac
    75361 tgctttgagg accttagact ggatcgtatc ataagtcacc ttgctatcgt caacaaccgg
    75421 acctgtttct ttctgggcag gagtatcatc cgcttttacg ccttcttgat tgtctgtttt
    75481 aacgctgaca actgtacggt cattgccata agttcctgcc ttgagaagga tcttcttctc
    75541 atttttaaga ttatcattga ccgccccagg cagtgtcact gtgtcaaaga gattgacatc
    75601 gttattgctg gcattgagtt gtccatctga cttgagagtg atagaaagac ggtttacaga
    75661 acccggttct ggtgcaacta cacggttgcc tttataccat gtgctattac ctggagtttt
    75721 gtattcccag aaccagccat ccttgtcata accgacaaaa acattattat tggtatcttt
    75781 aaatttcagg aagacaccaa agcgtgattt gcccttttca gaatcttctt tgaaggttaa
    75841 atcaacagtt gcatttccat tggcatcaac ggtcaagccc ttcttttcaa acagggctgg
    75901 tttgcctgcg ttatcatttt gagcagttga gaatagttgg ttgtagcgga cacctttttc
    75961 ttctcggata gtgactgttc cctgttgttc ttttttctct accgtttgcc attcaggagt
    76021 taccgtctta ggtgtttcag gtttagcagc tgcaggttta tcctcttttg gtttttcttc
    76081 agccggtttt tctttttcaa gtgctaatag ttcttcttct gtcttaggtc catctgtaac
    76141 ttctggagaa ccttggtctt ctcccacctt aggcgcttca aaatcacgcc catcattctc
    76201 gtttgctgtt gcaagagcag tagctaaatc agctggtaag ttcgccgtgg aaccagactg
    76261 cacgctatct gcaagaaccg gacttgtccc aaagaatgca gctccaatca taacagaagc
    76321 aacacctaat gaaaatttcc gaatactata tttacaacgt ttttcaaata atcctttatt
    76381 cataaacttc taaatccttt cattttttag caagcgttta catttccttt ttaaaaaata
    76441 ctccttcctc tgaaagtgca atgcttaacc ctgataaata aaaaataatt gtacttttaa
    76501 tataacaaat aatagctgag aaagcaatag gaaacaagta aaattaacaa aaattttctc
    76561 tattctgaca aaaagaggct ccaacttttg ggggtcagta catttagaat ctttctttac
    76621 aaatgtaaaa aaggattcag cattcaagag aaatactaaa tcctttctta tattttgcaa
    76681 cagttatttc acatgttttg cgagatcttc ttgagccttt ttattagact cttctttttc
    76741 tttcatccat ttttcctgag ctttttggta ttcatctaca gtgactgcct tgtcttgaag
    76801 ttccaagtat ttatacaaga ctggttcact tgtaccttta tttcctgaca atgcaaatgg
    76861 tattgtaaat ggtaccatct tagacaagat tgggcgccct gtacgagatg tagttggaat
    76921 aatcaaagca ctatctgtca accaagcttg ggctgcagcg tatttatcat agcgtttagc
    76981 aacatctgta gcctcatcac cagcctcagt gaccaatttt tcgtagtcat atagacctac
    77041 ttttttagca gctacattat cttcccctga gtcaaaccct aaatatgttt tagtactttc
    77101 tcctacagaa ggtttgataa tatcaaggta ggttgatgga tcggcaaagt ctggacccca
    77161 accgacatta tctgataaat cccagtcttc gccagcagca ttttcagcaa aatatgtaat
    77221 attgtttact tcgtcttttt gtagttgttg gatatcaata atgacattat cagctcctaa
    77281 agttgcttcc aaggattgtt tcatagattg gacgcgctga acttttgtag ttgctgtctg
    77341 gtcaactggc atatccaaat gaattgggaa agtcacacct tctgcttgta aggctgattt
    77401 agctttagca aattcagcct tggctttttc tggattgtaa agaccatcct gagaatctgc
    77461 aagattaaca tccttccatt catccccata agtgaccaat ttctctttga ccatatcgcc
    77521 aaagttttta ccatctgctt gaacaaatgt tggtggaaca aagatattac gtaagatttt
    77581 gcttgctcca gtttgtccat tcaactgaga ggcataggct gtacgatcaa aaccaaaggc
    77641 aatagcctga cggaaatcct tgtttaagag agccttttta gtcgatgcct tttgttcgtc
    77701 gctggtctta gatgtatatt tataggactg acggtcaata tttgtaccaa ctagatacgt
    77761 aatagagcct tgttgagtat agacaatatt gtccttcata ctcttctcaa gctctgcgaa
    77821 acttgcactt gttggataga gacgagctgc tgtaaggcta ccatctttaa agttttctgc
    77881 aggtttgctg gtatcttgac catcccagaa tgacaattta actttgtcaa catgcacatt
    77941 gtccttatcc cagtagttcg gatttttcgc aaattcaaca gaggattttg tcacaatgga
    78001 tttcaacaaa taaggaccgt tatacaagag actacttgga tccgtcgctt tggcaaaatc
    78061 atcccctttt gagttcaaaa actcttcatt aactggcgca agcacaccca tggttgtctt
    78121 agaattccag aagctttctg gtttgttcaa agtgtactga actgtctgat catccaaagc
    78181 cttaattcct acttgtgaga aatctttgat ttcccctttt acataggcat ccaacccttt
    78241 gattgattct tgaacaaggt aaagagcatc tgatttttta tcagcagcat attttagtcc
    78301 tgttacaaag tcttgagctt tgactgccgc gtattcttca ccttcagaag tataccattt
    78361 tgcatcctta cggatagtat aagtgtaagt caatccatcc ttggatacag accaatcctc
    78421 agccatagac ggcacaaagt tcccgtagcg atcattttct agcaaaccat caaccacgtt
    78481 actggtaata tttgctgtcg cagccttagc agttgtcaaa tagttgaggt tatcagggtc
    78541 tgtctcataa atgtatgaga atgtcttctc acctttagtg cttgaacctg atccagagca
    78601 tgcagctaaa gtagtcgccg ccaataatgt cacgcccgca agggcaagta gttttgaact
    78661 tttcatcctt ttctccttta aaactttctc tccattatag actcttttca gaaagttgtc
    78721 aacagaattt tcagaatttt tgaaaattat ttttcaaata acatctttgc aaaaaatatg
    78781 aatatcgtaa ccgcccaata acgaagtcta ttgaaaaatc tccagactag agaactcacg
    78841 gatagttcct aatctggaga tttcttattt gcacttttct tgtacaactt tagtccacgg
    78901 taaataggcc tctaaaatct ctttgtttac gagagtttcc tcgtttggaa gacattctag
    78961 aagataggat agatatttct cgctatttaa t
//
LOCUS       DAVBCA010000002        67315 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.002, whole genome shotgun sequence.
ACCESSION   DAVBCA010000002 DAVBCA010000000
VERSION     DAVBCA010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 67315)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 67315)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..67315
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.002"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(134..1882)
                     /locus_tag="VQU19_000080"
     CDS             complement(134..1882)
                     /locus_tag="VQU19_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2479412.1"
                     /translation="MKRQTVNQTLKRLVVDLANHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFADRQGNGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGST
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKELSIDIPAGSKVAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRVSLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVIA
                     AAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTISRVFLAIPKILILDEATSS
                     IDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            complement(1884..3608)
                     /locus_tag="VQU19_000081"
     CDS             complement(1884..3608)
                     /locus_tag="VQU19_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2479413.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFLSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFAESPENIHSELEQKQVTSGRVLQV
                     QELTFTYPDAAQPSLRDISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGLNQEVTDQELWQALEIAQAK
                     DFVSDKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENLPNMSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHGKED"
     gene            complement(3666..4604)
                     /gene="msrB"
                     /locus_tag="VQU19_000082"
     CDS             complement(3666..4604)
                     /gene="msrB"
                     /locus_tag="VQU19_000082"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HET2479414.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLI
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            complement(4746..4823)
                     /locus_tag="VQU19_000083"
                     /pseudo
     CDS             complement(4746..4823)
                     /locus_tag="VQU19_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(4899..5768)
                     /locus_tag="VQU19_000084"
     CDS             complement(4899..5768)
                     /locus_tag="VQU19_000084"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HET2479415.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTKGVRVEAK"
     gene            complement(5770..7056)
                     /locus_tag="VQU19_000085"
     CDS             complement(5770..7056)
                     /locus_tag="VQU19_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HET2479416.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILALDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            complement(7207..7944)
                     /gene="mecA"
                     /locus_tag="VQU19_000086"
     CDS             complement(7207..7944)
                     /gene="mecA"
                     /locus_tag="VQU19_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HET2479417.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            complement(8144..9178)
                     /locus_tag="VQU19_000087"
     CDS             complement(8144..9178)
                     /locus_tag="VQU19_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HET2479418.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPKESAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            complement(9207..10640)
                     /locus_tag="VQU19_000088"
     CDS             complement(9207..10640)
                     /locus_tag="VQU19_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HET2479419.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGILARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFIAKMLTKEN"
     gene            complement(10656..11642)
                     /locus_tag="VQU19_000089"
     CDS             complement(10656..11642)
                     /locus_tag="VQU19_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET2479420.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQIYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGHAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            complement(11644..12747)
                     /locus_tag="VQU19_000090"
     CDS             complement(11644..12747)
                     /locus_tag="VQU19_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HET2479421.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDLEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLTRRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYASKLQIIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            complement(12737..13582)
                     /locus_tag="VQU19_000091"
     CDS             complement(12737..13582)
                     /locus_tag="VQU19_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET2479422.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKDFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLTLDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            complement(13861..15135)
                     /gene="psr"
                     /locus_tag="VQU19_000092"
     CDS             complement(13861..15135)
                     /gene="psr"
                     /locus_tag="VQU19_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HET2479423.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            complement(15132..15980)
                     /gene="pheA"
                     /locus_tag="VQU19_000093"
     CDS             complement(15132..15980)
                     /gene="pheA"
                     /locus_tag="VQU19_000093"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HET2479424.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYIDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            complement(15977..16453)
                     /locus_tag="VQU19_000094"
     CDS             complement(15977..16453)
                     /locus_tag="VQU19_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HET2479425.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRHVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     LRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            complement(16446..17729)
                     /gene="aroA"
                     /locus_tag="VQU19_000095"
     CDS             complement(16446..17729)
                     /gene="aroA"
                     /locus_tag="VQU19_000095"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HET2479426.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKEYTRNHTEDMLQQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIAPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSATLIVESSDLKGTEIGGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            complement(17821..18159)
                     /locus_tag="VQU19_000096"
     CDS             complement(17821..18159)
                     /locus_tag="VQU19_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HET2479427.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            complement(18170..19273)
                     /locus_tag="VQU19_000097"
     CDS             complement(18170..19273)
                     /locus_tag="VQU19_000097"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HET2479428.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLEVIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVIK"
     gene            complement(19283..20449)
                     /gene="aroC"
                     /locus_tag="VQU19_000098"
     CDS             complement(19283..20449)
                     /gene="aroC"
                     /locus_tag="VQU19_000098"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HET2479429.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            complement(20459..21526)
                     /locus_tag="VQU19_000099"
     CDS             complement(20459..21526)
                     /locus_tag="VQU19_000099"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HET2479430.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEEKGLMPAGITQSITEMCQKFGLPVDYENWKVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSATIHPVSLEEMKDYLVK"
     gene            complement(21545..22399)
                     /locus_tag="VQU19_000100"
     CDS             complement(21545..22399)
                     /locus_tag="VQU19_000100"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HET2479431.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLVETVANIRRYQMFGINLSMPYKEQVIPYLDELSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKKMPTEEIW
                     QSLTEKYQ"
     gene            complement(22389..23066)
                     /locus_tag="VQU19_000101"
     CDS             complement(22389..23066)
                     /locus_tag="VQU19_000101"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HET2479432.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            complement(23063..24226)
                     /locus_tag="VQU19_000102"
     CDS             complement(23063..24226)
                     /locus_tag="VQU19_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HET2479433.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQAFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGLDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDERRFIVMDVFEYF
                     KYAKRKNLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            complement(24911..26545)
                     /locus_tag="VQU19_000103"
                     /pseudo
     CDS             complement(24911..26545)
                     /locus_tag="VQU19_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(26526..27275)
                     /locus_tag="VQU19_000104"
     CDS             complement(26526..27275)
                     /locus_tag="VQU19_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2479434.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLTSSDLETSLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSAPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGSVEN
                     LRKDHPDQFLESIYLSLAGRKEEVADASQGH"
     gene            27454..28908
                     /locus_tag="VQU19_000105"
     CDS             27454..28908
                     /locus_tag="VQU19_000105"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HET2479435.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKEQGIQPMADVVL
                     NHKAAADNREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNGFHWHWYHFT
                     GTDYDAKRSKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(28998..31616)
                     /gene="alaS"
                     /locus_tag="VQU19_000106"
     CDS             complement(28998..31616)
                     /gene="alaS"
                     /locus_tag="VQU19_000106"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HET2479436.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLISPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGS
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNTSQLSSKLVAIVADNAEVGAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKIVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDAKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQAKIQELLDAVAGKL"
     gene            complement(31638..32123)
                     /locus_tag="VQU19_000107"
     CDS             complement(31638..32123)
                     /locus_tag="VQU19_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HET2479437.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSQISKEILTLLPRFEIQLLDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(32398..32637)
                     /locus_tag="VQU19_000108"
     CDS             complement(32398..32637)
                     /locus_tag="VQU19_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2479438.1"
                     /translation="MKMSTFFNKSFWPTFMIVNQTAILFHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILEK"
     gene            complement(32890..33960)
                     /locus_tag="VQU19_000109"
     CDS             complement(32890..33960)
                     /locus_tag="VQU19_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET2479439.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDLQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQDS
                     AYAFINFMLKPENALQNAEYVGYSTPNIPAKELLPEETKEDKAFYPDVETMKHLEIYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(33957..34730)
                     /locus_tag="VQU19_000110"
     CDS             complement(33957..34730)
                     /locus_tag="VQU19_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2479440.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIITGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(34727..35533)
                     /locus_tag="VQU19_000111"
     CDS             complement(34727..35533)
                     /locus_tag="VQU19_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2479441.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(35514..36671)
                     /locus_tag="VQU19_000112"
     CDS             complement(35514..36671)
                     /locus_tag="VQU19_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2479442.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFESEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(36730..37680)
                     /gene="murB"
                     /locus_tag="VQU19_000113"
     CDS             complement(36730..37680)
                     /gene="murB"
                     /locus_tag="VQU19_000113"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HET2479443.1"
                     /translation="MSVREKMLEILEGIDIRFQEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARLVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESLSVAKMYAGGFTPCKR"
     gene            complement(37792..38544)
                     /locus_tag="VQU19_000114"
     CDS             complement(37792..38544)
                     /locus_tag="VQU19_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
                     /protein_id="HET2479444.1"
                     /translation="MTIHIIITMLLLLAFLIGSIWFAKKKYQINLAVLGLGAVAFFVS
                     SQILEKLVHILILHPQKDGSIALLQDHPLIYIIYGLAMAAFFEETARLVFFKWFEKKR
                     SLEKADALAYGLGHGGLELIFLGLTSLLNLYIVLSAVQTQNPQVMQLLSENMLKTIQS
                     LSVWQIYLLGFERILALGFQLLLTVWVYQAVRQKKWIYLLTAYGLHAFFDLAPSLFQV
                     GWLTNPVLVEVILALELVLVAYGTKEIFCKKS"
     gene            complement(38554..39285)
                     /gene="budA"
                     /locus_tag="VQU19_000115"
     CDS             complement(38554..39285)
                     /gene="budA"
                     /locus_tag="VQU19_000115"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HET2479445.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFLHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            39427..40698
                     /locus_tag="VQU19_000116"
     CDS             39427..40698
                     /locus_tag="VQU19_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HET2479446.1"
                     /translation="MKKQSKYKEVVSYLKNGIESGRFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEEHVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(40718..41533)
                     /locus_tag="VQU19_000117"
     CDS             complement(40718..41533)
                     /locus_tag="VQU19_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HET2479447.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVEAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEILSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQAGKIDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGTYQSYLEKAASLTEVEE"
     gene            complement(41690..42343)
                     /gene="phoU"
                     /locus_tag="VQU19_000118"
     CDS             complement(41690..42343)
                     /gene="phoU"
                     /locus_tag="VQU19_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HET2479448.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(42355..43113)
                     /gene="pstB"
                     /locus_tag="VQU19_000119"
     CDS             complement(42355..43113)
                     /gene="pstB"
                     /locus_tag="VQU19_000119"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET2479449.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            complement(43126..43929)
                     /gene="pstB"
                     /locus_tag="VQU19_000120"
     CDS             complement(43126..43929)
                     /gene="pstB"
                     /locus_tag="VQU19_000120"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET2479450.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(43940..44824)
                     /gene="pstA"
                     /locus_tag="VQU19_000121"
     CDS             complement(43940..44824)
                     /gene="pstA"
                     /locus_tag="VQU19_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HET2479451.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(44814..45731)
                     /gene="pstC"
                     /locus_tag="VQU19_000122"
     CDS             complement(44814..45731)
                     /gene="pstC"
                     /locus_tag="VQU19_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HET2479452.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(45731..46609)
                     /gene="pstS"
                     /locus_tag="VQU19_000123"
     CDS             complement(45731..46609)
                     /gene="pstS"
                     /locus_tag="VQU19_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HET2479453.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(47183..48487)
                     /locus_tag="VQU19_000124"
     CDS             complement(47183..48487)
                     /locus_tag="VQU19_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HET2479454.1"
                     /translation="MKFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQIFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEEFVKYAAGET
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(48488..49261)
                     /locus_tag="VQU19_000125"
     CDS             complement(48488..49261)
                     /locus_tag="VQU19_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HET2479455.1"
                     /translation="MKSKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLASFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(49251..49529)
                     /locus_tag="VQU19_000126"
     CDS             complement(49251..49529)
                     /locus_tag="VQU19_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HET2479456.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGKGKISLEK"
     gene            complement(49529..49930)
                     /locus_tag="VQU19_000127"
     CDS             complement(49529..49930)
                     /locus_tag="VQU19_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HET2479457.1"
                     /translation="MITLFLSPSCTSCRKAKTWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(50140..50757)
                     /locus_tag="VQU19_000128"
     CDS             complement(50140..50757)
                     /locus_tag="VQU19_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HET2479458.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLALVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYESFFGYLCLKSRRK"
     gene            complement(50747..51520)
                     /locus_tag="VQU19_000129"
     CDS             complement(50747..51520)
                     /locus_tag="VQU19_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HET2479459.1"
                     /translation="MKYKGYLIDLDGTIYKGKDQIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKEKPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(51531..52268)
                     /locus_tag="VQU19_000130"
     CDS             complement(51531..52268)
                     /locus_tag="VQU19_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000524807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HET2479460.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIVEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSDFDKKLIRGPKYESLEESISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKA"
     gene            complement(52273..53403)
                     /locus_tag="VQU19_000131"
     CDS             complement(52273..53403)
                     /locus_tag="VQU19_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HET2479461.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(53487..53876)
                     /locus_tag="VQU19_000132"
     CDS             complement(53487..53876)
                     /locus_tag="VQU19_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HET2479462.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(53892..54275)
                     /locus_tag="VQU19_000133"
     CDS             complement(53892..54275)
                     /locus_tag="VQU19_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HET2479463.1"
                     /translation="MLEVAYILVALALIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            complement(54276..55064)
                     /locus_tag="VQU19_000134"
     CDS             complement(54276..55064)
                     /locus_tag="VQU19_000134"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HET2479464.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            complement(55057..55992)
                     /locus_tag="VQU19_000135"
     CDS             complement(55057..55992)
                     /locus_tag="VQU19_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HET2479465.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLSETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(56122..56298)
                     /locus_tag="VQU19_000136"
     CDS             complement(56122..56298)
                     /locus_tag="VQU19_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HET2479466.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(56438..57145)
                     /locus_tag="VQU19_000137"
     CDS             complement(56438..57145)
                     /locus_tag="VQU19_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HET2479467.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            57296..58324
                     /gene="queA"
                     /locus_tag="VQU19_000138"
     CDS             57296..58324
                     /gene="queA"
                     /locus_tag="VQU19_000138"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HET2479468.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIINMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDSMFIY"
     gene            complement(58995..59384)
                     /locus_tag="VQU19_000139"
     CDS             complement(58995..59384)
                     /locus_tag="VQU19_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET2479469.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTDWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMKVNQWFQVGGKWY
                     YVNASGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(59438..60145)
                     /locus_tag="VQU19_000140"
     CDS             complement(59438..60145)
                     /locus_tag="VQU19_000140"
                     /inference="COORDINATES: protein motif:HMM:NF019142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET2479470.1"
                     /translation="MFRRNLNTSFVHAADGIQYVRDDTRDKEEGIEYDDADNGGIIVK
                     VATKPKVVTKKISSTRIRYEKDETKDRSENPVTIDGEDGYVTTTRTYDVNPETGHVTE
                     QVTVDRKQATDTVIKVPAKSKVEEVLVPCATKYEADNDLSAGQEQEITLGKNGKTVTT
                     ITYDVDGKSGQVTESTLSQKEDSQTRVVKKGTKPQVLVQEIPIETEYLDDPTLDKSQE
                     VEEVGEIGKLLLLQSIL"
     gene            complement(60845..61396)
                     /locus_tag="VQU19_000141"
     CDS             complement(60845..61396)
                     /locus_tag="VQU19_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2479471.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDIEITRNSIRNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGNGMMTETLKAILDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(61794..62618)
                     /gene="nadE"
                     /locus_tag="VQU19_000142"
     CDS             complement(61794..62618)
                     /gene="nadE"
                     /locus_tag="VQU19_000142"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HET2479472.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            complement(62615..64075)
                     /locus_tag="VQU19_000143"
     CDS             complement(62615..64075)
                     /locus_tag="VQU19_000143"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HET2479473.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(64191..64679)
                     /locus_tag="VQU19_000144"
     CDS             complement(64191..64679)
                     /locus_tag="VQU19_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2479474.1"
                     /translation="MKNRFYYYQLLDEREEQLINKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYVIYLPWVFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(64669..64878)
                     /locus_tag="VQU19_000145"
     CDS             complement(64669..64878)
                     /locus_tag="VQU19_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2479475.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            complement(65268..65710)
                     /locus_tag="VQU19_000146"
                     /pseudo
     CDS             complement(65268..65710)
                     /locus_tag="VQU19_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000640911.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(66002..66808)
                     /locus_tag="VQU19_000147"
     CDS             complement(66002..66808)
                     /locus_tag="VQU19_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2479476.1"
                     /translation="MILKDINFALNKGEIVGLVGRNGVGKSTLMKILVQNNQPTSGNI
                     ISSDNVGYLIEEPKLFLSKTGLENLKYLSNLYGVDYNQERFRSLIQELDLTQSINKKV
                     KTYSLGTKQKLALLLTLVTEPDILILDEPTNGLDIESSQIVLAVLKKLALNENVGILI
                     SSHKLEDIEEICERVLFLENGLLTFQKVGKDSHNFLFEIAFSSATDRDIFITKQEFGD
                     IVQEEGLRITMSGNIQSSELFKFFNENSIKVVDFETKKETLKDIYLNRSK"
     gene            complement(67214..>67315)
                     /locus_tag="VQU19_000148"
     CDS             complement(67214..>67315)
                     /locus_tag="VQU19_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HET2479477.1"
                     /translation="VPQPVQSGDMVRALKEGLINLYKEDGTSVTVRA"
BASE COUNT        20052 a        15155 c        12520 g        19588 t
ORIGIN      
        1 acctacggct agcttcctag tttgctcttt gattttcatt gagtattaca gtaaacaatt
       61 tttctagcta ttgtaacaaa aaagtcactc gaaggcaact tttttcgtcc ataaactttc
      121 aaaagagaat ggcttattca gaactaaaag ccgcagcttt ttgcatttgg taatacttac
      181 cctttctatc catgagttct tgatggttac catattcaac aatatcacca tctactaaga
      241 caagaattaa atccgcatcc tgaatggttg acaaacggtg agcaatgatg aagcttgtgc
      301 ggcccttcat gagttttgca aaggcatcct gtaccagcac ttctgtccgt gtatcaatgg
      361 aagaagttgc ctcgtctaag ataagaatct ttggaatagc cagaaagact cgggatatgg
      421 tcaagagctg agcttggccg acagagagag attctccagc attttccaac ttggtatcgt
      481 atccctgtgg caactgttgg atgaaaaagt ctgcattagc tgctttggca gcagcaatta
      541 cttgctctcg actggcttca ggattgccaa aggcaatatt atcatgaatg gtcccttgtg
      601 tgagccaggt ttcttgaagc accataccaa actgctgtct caatgatact cgtgtataat
      661 cataaatgga ttgcccatcc agcaagatat ctcccgagct aatgggataa aaacgcataa
      721 ggagattgat aagagttgat tttccagcac ctgtcggacc aacgatggct accttactac
      781 cagctggaat atcgatagac aactccttaa tcaaaatttt ttcaggatgg tagccaaaag
      841 agacatgttt aaaggaaata gctcccttaa cttggtcact ggtcaagact tccttacctg
      901 tttcagccac ttcagggcta tctaagaccc catagatacg ctctacgcaa gccagagcac
      961 tttgcaactc agctagcact gaagaaatat cgttaaaggg cttggtgtat tgctgaacat
     1021 agttcaaaaa agtcactaaa cgaccgacgg tcaaggttga acccatcatg atacgataag
     1081 ctcctactcc agctaaaagg gcataaatga gtgcatttac aaagcgagtc gaaggattga
     1141 ccgttgaaga ataaaagatg gctgactgag aatagcctga gtagttgtca tgagcctcac
     1201 gcaatctttg gataaattct gtttgagcat tgaaggactg gattatagtc tgctggctaa
     1261 gcgattcttc aatcaactga gtctgaattc ccctcgtctc tgtttgcttc tggaagagat
     1321 gataggatct cttggcaata aagcgtgaaa tcaccatgga cagtggcgtc aacagcaaga
     1381 ctaagagagt catgaggaga tgaatttgga gcatggctag aatactaacc aaaatcatca
     1441 aaacaccaat gaaaaattgg ttaaaaatca tggtcaagcc agctgccaac tgttcgatat
     1501 ccgtggttac acgactgacc atctctccat tgccttgccg atccgcaaaa gcaatcggta
     1561 accgatggag tttatggatg attcgctctc gtaaatctct ggtataagag aagattagac
     1621 gattatagag gagaggattg gcccattgta ccagagtatt tcctattacc accaagagca
     1681 tctggagaaa aatctgccaa aaaactggtg atgaaccagc cactaggact tggtcaatga
     1741 cctgcccaat cagaataggt aggtaaattg ataagccaac ttgggcaata gttcctagaa
     1801 aggctaggaa aaggaggaag ggatggtttg ctaaatctac gactaaacgt ttgagcgtct
     1861 ggtttacagt ttgtcgtttc attctagtcc tcctttccat gttgggatgc attgatttca
     1921 cgatagactt gactggattt catcaagtca tcgtgcttgc caacagctag caactcacct
     1981 ttttccaaga ggagaatctg gtccgccatc tggagtgtcg aagtccgttg agaaatcaag
     2041 attaagctca tatttggcag attttcgcgg atagctttca agagcttgga ctctgtaatg
     2101 gtgtccagtg ctgaggtcgc atcatctagg atgagaaacg gagcctggcg caagactgct
     2161 cgtgcgatag acagcctttg tttttgtcca cctgagaaat ttcgccctcc tgcttcaact
     2221 agagcatcca agagtccttc cttatcactg acaaaatcct tagcttgcgc aatctccaag
     2281 gcttgccaga gttcttgatc agtcacttct tgatttaaac ctaaagtcaa gttggaacga
     2341 atagttccct taaagagttc gaccttttga ggtacatagg caatccaaga ccgccactgc
     2401 tccaaattaa gaggactacg tccattttga taaaggtcaa tgttcccctt gtctactgga
     2461 taaagtccaa gtaagagttg caccaagctt gatttaccag aaccagtccc cccaatgata
     2521 ccaaggattt gtccttgagt catatcaaag gaaatgtctc tcagagaagg ctgggccgca
     2581 tcaggatagg taaaagtcaa ttcttggact tgtaaaaccc gaccactggt aacttgcttt
     2641 tgttctaatt ctgaatggat gttttcggga gattccgcaa agacctcctc gattctcttg
     2701 gctgagatat aggactggtt gagggaattg atcagcatgg ctagcttgac caattccacc
     2761 aaaatctgta agaggtaatt gataagagca atgagagcac cttgactgag tactcctcct
     2821 tgaattgaaa tatagccttg ccagataata acgagaagag ttccattgac aatcagatag
     2881 gtcagaggtg ttaataaact agacaagaaa cctgtctttt cttgtaatct agcataaact
     2941 tggttaaggg tttgaaaaat ctgtaactct cgtttttctt gaccaaaagc acgaataacc
     3001 cgcatccctt gcaattgctg gcgcgtttcc tgaaccagtt ggtccgtttt ctttctgaga
     3061 ctactgtaga gaggattgac caatcgagat aaccctacaa tgacaatggt caaaatggca
     3121 accatgacta agaaccagaa agtcaactca gctgagattc gataagccat aaaaatggca
     3181 ccaaaaacga taatgggcgc tcgtaaaaag agacgcagga attgattgat accagtctga
     3241 atctggtagg tatccgaagt caagcgagta accaaactag aagttgtcag acggtctctg
     3301 ctgtcctttg gcaaggaaag aatatgacga taaagatcgt ttgtcaattc cttagcaaaa
     3361 cctactgctg cctttgctga gtaaaattga gctatcaagg ccactaaaac gccaattact
     3421 gcaaagataa ggagcaggcc aatctgcatc cagagatgac cttgatctcc ctgaggtaaa
     3481 gattggtcaa caatcccagc aatcaccatg ggaaccaaga gctcaaaaac agcttctaac
     3541 agcttgaaca agggggctaa aattgattcc ttgatgtagg gtttgaagta agataatagg
     3601 tgtttcataa atcccttcta ttcatattct agaaatgaag aaagtgggaa gccccactct
     3661 ctgttttatt tgtttaagta aggcaataga tagccatatc ctgctttttc catctcatcc
     3721 ttggccacaa agcgtaaaga agcagaattg atacagtaac ggaggccgcc taactcccgc
     3781 ggtccatctg tgaaaacatg acccaagtga gcactgcctg aacgagaacg aacttcaatt
     3841 cgctccattc catggctcag atccttgtaa taatgaatca actctttgga aatcggacgg
     3901 ctaaaacttg gccaaccaca acctgaagca aacttatcct tggcaaaaaa gagtggctca
     3961 cctgtcgtaa tatctacata aatcccctct tcaaaggttt ggtcataggc attggtaaat
     4021 ggagcctctg tagcagcttc ttgtgtgaca cgataagact cttcagatag actggccttc
     4081 aacacctctt gactaggctt ttcatagttt gctgcatcaa tcaatggctt atcagcatcg
     4141 gtcacatcga tatgacagta acctgaagga ttcttcctga gatagtcttg gtggtagtct
     4201 tcagccagaa tgtagtggcg taattgctcc acttctactg caatctttcg acccagcatg
     4261 cgttcctgct cctgcaccac tgtgtagata gctggcaaat ctgcttcatc ctgataataa
     4321 atcccagttc gatattggcg accacggtca ttcccttgtt gattgataga tagaggatcg
     4381 ataactcgga aataataaag taaaatctct ctgagtgaca cttccttctc atcgtaaatc
     4441 acttggaccg tttctgcatg gtctgtttcc ttgatcaact ggtaattggt cgtttcgact
     4501 tgaccattag cgtagccaac actggtttct agcactccag aaatgcgtga aaaatattcc
     4561 tctaggcccc aaaaacaacc acctgctaga taaatttctg ccatctttat ttctccttta
     4621 tcacgttttt aactaatact cttcgaaaat ctcttcaaac cacgtcagcg tcaccttacc
     4681 gtaggtatgt tactgacttc gtcagttcta tctgcaacct caaaacagtg tcttgagctg
     4741 acttcgtcag ttctatctgc aacctcaaaa cagtgttttg agcagcctgc ggctagcttc
     4801 ctagtttgct ctttgatttt cattgagtat aaacttcttt tcacaaaaag gatatgaaac
     4861 cctctggtca agagtttccc catcctatct tctattcttt attttgcttc tacacggaca
     4921 cctttggtat caactctcaa gtcatgcagt tttcctttga aaggttgctt ttccaattct
     4981 gccttaattg ttggcatctt gtcatgagaa gccagaacca taactgtcgg cccagcacca
     5041 gaaaggtagg ttgcataggc cccattttct ttggtcactt gcttaatcat cgcaaattct
     5101 cttaccaagt cctgacgata gcgctcatgg aagaggtctc cctcgattgc ttgcccagcg
     5161 gtcaccatgt ctcctgccaa caaggcagca accgctacat tggcgataga acttgcagca
     5221 acagcttcct tataagacaa ttttttaggc aagacactac ggctgtcgcg agtacgtaat
     5281 tcatagtttg gaatgtaagc tagaaaatca cactctggaa agtctgctac gatagcagag
     5341 acttgccctt caacagaact tgcaataacg agattaccat aaatggctgg agccacattg
     5401 tcaggatgcc cttcaatctt ggtcgctaac tgcaattttt catggtctga taagttgagt
     5461 tgacccagtt ggttggctag ttcaatccca gcaacgataa ccgagctgga agaacccaaa
     5521 ccgcgcgcca aagggacatc actggtcatt ttcaagcgtc ttggttgcaa gtctggtaca
     5581 atttgcaaag cgattttaag caagagatta cgctcgtcat gtggaatcca tttgccaatc
     5641 tggtgttcaa tcagccactc atctcgttct tcgcagacct caatttgaag atacttggtt
     5701 acagctacac cgaccgagtc aaaacctggc ccgatattgg cactggttgc aggtacaata
     5761 atcttcatct tattctccta gcaccttgaa ggtattcaag aggtcgaatt ctgaaacctt
     5821 cttcaattca gctgagacat tttcaagctg ggctttatta atcttgtgtg tgatgataac
     5881 gacacgcgcc ttgtcaccct ctttgccatc ttgaaggatt tgcttaaagg aaatatcttg
     5941 agcattgaag atttcagcca acttcaagac ctgacctttt gagtctagag ccaagattga
     6001 gaaatagtag tttgctttga catcttcagg atttgccaag accaagtcac ggctatattc
     6061 gttgaagtct ttgccaatag taccatcatt caaacgacga acgatacgga caatatcagc
     6121 tacaacactt gttgcagttg gtttttgacc cgcacctggt ccgtagtaca tagactcacc
     6181 aataccgata gattctacaa agacagcgtt cattacgcca ttcacactag caagtgggtg
     6241 cgctttaggt aggaaggttg gagtcacttc tgcagcaata cctgaagaag tttcctcaat
     6301 agaaccaacc aatttcacta cgtaaccaag ctcttgagct acagctacgt cttctggtgt
     6361 gatattgcgg attcccttgt gggctacatc atcaaaggca atcttcatgc caaaggcaaa
     6421 ttggctcaaa ataaccatct tgtaggctgc atcaatccca tctacgtcat tcgtcggatc
     6481 gctttctgca aatcctagac gttgtgcttc cgcaagagca tcatcgtaag accagccttc
     6541 ttccaccatc ttggtcacca tgaagttgga agttccgttg actactccaa gcacgcgcgt
     6601 aattttatca gaagccaagg aatttgctaa agtacgaaga attggaatcc caccagcaac
     6661 tgctgcttcg tagtaaagtg ctaccttgtt agcttgagcg atttctagca attctgcgcc
     6721 atggacagct aaaaggtcct tgttagcagt aacaacgtgt tttccagctt ccaaggcacg
     6781 agtgataaag gttttagcag gctcaatacg ccccatcaat tccactacga tagtaatatc
     6841 ctggtctgat aaaatatcat ccacattggt tacaaagtta aagtcattcc ctgctgcaag
     6901 caagcgattt ttttcatctt catccttgac caatacctta gcaactttga tatctgaatg
     6961 tgctgattga ttgatttttc ctccattttc ctttaggagg aaaggcacac cacttgcaac
     7021 ggtaccaaat cctagtaaag caattttaac tgtcatcttt atctcctcga aattttctaa
     7081 tatagccatt ataacagaat tttgtgaaaa ttcctattat agtaaatcac tatttcagta
     7141 taaaaagaaa aaacgaatca gacgattcgc tcttcttaaa atctgaaaat agctttccag
     7201 aaaagattag ccgatttttt gcagattgag cactgcatcg tgactcatca agacttgacc
     7261 atactcttgt aagactgagc gactgatatc actatcgtct gcaaactcgc gcatacgggc
     7321 caacagccaa gctggatatg ggcttggatg attttcaata tccactaaaa tggtcaaata
     7381 atagcgctcg ttcattttgt agagttcaga agtttccatt tcaaaagtca ctgtcttggc
     7441 aaaagctacc aagtcagcca acttagcaaa agaaaggatg tagtagatgt aaggttcttt
     7501 cttactctca gcttcttgtt cagcctgctc ttgctcttct tccttggctt caacttgctc
     7561 aagagattga atggcttcga tatcatcctt ggttttgtct gcgatgcttt tttccagggt
     7621 tttgataaat tcatctggag acatttgagc caattcttcc atatctggca aatccgataa
     7681 gtcttcaaaa tctagatttt ggtcaatctt tgacttggtc acaaagacat ctaccttatc
     7741 aggttttgga gtcacacgga agctcaacat gcctgtatcc agaaagctat caggcatctc
     7801 tagctcatcc aagatagcat aaaagaactc ttctgttttt tcttgaggaa cgagaaagtc
     7861 agcaatctcc attccacgat ccatcaaatc ctctaaagac atcgtgattt ttaaagttgt
     7921 atcactaatt tgtttcattt tcattgctag taacctcata ctttcagttc tatctattat
     7981 actagatttt tacgatttta tcaaaagaag gctcctctat acggatagat tttccctagg
     8041 gtctttctat aggagactcc aagagaaaat ttctgcagac agatagaaaa agccttcaaa
     8101 atcggctaag agccgatttt gaagacctta tacatcagaa tacttataat ttaaaggttg
     8161 ctacaccgag gatagaacga tttaagtttc tgagaatttg aagactttgc tcaaatttct
     8221 tataacgagt cactccgtac tcttcaacaa gaaggactgt atctctttcc aaaagagatg
     8281 atacatcctg taaatctaca aaatgcattc cttttaaagc ttcttgactc tgtttcaatt
     8341 tatctaggat agctttattt gagctaacga tggtcaattc ctgtccagta tttttgtatg
     8401 acaaaacatc tgctaggtta gcaattgttg taatctctgt tacaaaatca atttgatact
     8461 gagaaaaatc acctactcta ttgattgttg gattaaagag ataaactaac acatttccca
     8521 tcacaaccaa aatcacacaa accactccaa taacaactaa acgaagaatc agatttttca
     8581 catttaagcc aagcgctgtt tcaccatttg cgttcaattc tttagagttg atggtttcca
     8641 gtttttcaat tttcacattt gcataggcat gtttaaattt ctcaatcaac ccatcaattt
     8701 ttttctctaa caagtcattg gcatctttac ttgatgtcaa aattttcaca ccaacccctg
     8761 catcgtcaat catatagtag acggtcaatt ttttccacca atagtcattc gttgaatttt
     8821 tcaaggttgt ttctgtcgtg tctaattcac tggcaatttt tttcaactca ctgggttcta
     8881 catcattgaa aagataagct ccattcaaat taccatcaat caatttccca taaaaatcac
     8941 tataaccacc aatttgatga ttcaaaatcg ttttggccga ctcttttgga ggagtgattt
     9001 tatagataag ataagttgaa taacttgttg tatctttgac agtgttttta ttcctaactg
     9061 ctttaattgt aaatggtaca gcaatgagag caaataaagc gatgagagct aaaatatttg
     9121 cttttcgctt tttataaaga tttgcaaaca aatcagctac tgaataatgt tcaaacatga
     9181 tttttttctc ctttgtttag tagatactag ttttcctttg taagcatttt tgctataaat
     9241 ataatcacaa gaacaattcc ccagaattgc attgtaaata aattgaagaa actttctgaa
     9301 aagctgcttc ttggcataaa gaatagatta ttcaagatga gtagggataa agcaaatagg
     9361 attgtccttg agcgataggc tacttgcagc atggctataa ataatacgcc gagtaagaaa
     9421 ctaagcagaa agactccaat cataccatag tcggtataca actccatgat ataactactt
     9481 ccgataccat gccctttcag gtattccttg ttcaagacaa gataggatag attgtgggca
     9541 taactattac tatcaatagc tagttccaca ctattggttg tatgttcaaa ggcttttcct
     9601 ccgaaaatgg ctcccaaact cccccttgca aaataatcaa gaacaggacc aaaagtaaaa
     9661 ttacggaaat ctcggtaagg gaggctactg ttaaatagaa aacctcgagc cagaacacca
     9721 aaactagtcc cttgtttata gataaagtca agtaagatat cccagaaacc tgtatgggaa
     9781 acttggacat tatcccgtac ataattgagt actcccatcg ctaacatgag aataggagaa
     9841 cctacaaaaa tcgctaactt ttctttaaac ccaatccatt ttcctttttc agtttgctcc
     9901 cgcataaagt aataaacaaa agcaaataaa atacttaaaa taaagggatt tcgtgtccca
     9961 attgccaaat gaatagtatt agctgcaata aaggagacaa gcactgctgt ggcctgcaat
    10021 ttctttggct tggttgccag atacatacac attgcataga ccgtaaaggt agacaaaatg
    10081 taggtaaaat aaggcagttt actttcaaaa tttgcatagt aggcatagta ggaagtctgc
    10141 aaacgataca agagccgttc aaataaccga atgaaataga aaggataagt tagaagaaaa
    10201 actcctagtg atacaaagcg taaccgcttg atataaacct cttttagaga atttcctata
    10261 tttgctactt ttattttctt cctagctatg aagtaacgag ccagaatgcc tcctgtggtc
    10321 aagcccagaa tcgaaaccat gacaactata aaggcaaaac gataggctat tggatgatag
    10381 gtatccaaag caccatccct aaaataatca atggtcggtc ttgataccag aaatacaaaa
    10441 atggttaaat agaaaataaa atggattaag taatacttga tatcattcca acaagcaatt
    10501 aagctactaa ccaacaagaa caataaagta gaaagtaagc taacattatt attattaaac
    10561 agatacacaa ttccacttac tagcgtcaag gcataactga ctatggtcaa actaaataat
    10621 aatcgtttcc catcaatcac ttggtcaccc ccgttctaat gtaatttttt agatttttca
    10681 atatttttca gtaataagaa tcgatataag gaaatattta tgaatagggc caaagcacta
    10741 attcttctcc ccttacggaa aattggattc ctagaaatag caaaggcatg gccttttaaa
    10801 aaacgatgaa tctgagaata ggcttcaaac tgtttatact gatcatctag caacatctta
    10861 tccagaataa agaagtgggc ataggccaat ctgaaaaaag cgacctcttt caagtcagga
    10921 tagtttttca caacttcatt ataaaacttt tggtagatat caatataggc taaatccttc
    10981 tctgcatagg gtttggtcgt aatactatcc cctctatgga aatagtaata atagggttta
    11041 gtattaacca catacttctt ggccaacttg attaaatcaa aatggtaata ggcatcttcg
    11101 taaatcaacc ccttaggaaa ggatagggca gttgcaatct gtctcttgat tagcttattg
    11161 caaatcgtcc caggtatttt ttcacctatg aggtattcct ttagaaatgt ttgagaatca
    11221 cagacaaaat agtcatcctg attggctgac tgtgggcttt catcattagc atagacattc
    11281 atgacaccac agcttgaaac atccgcatct tcttgaacta attgctcata taagctctga
    11341 atcatttctg gatggatata atcatctgag tcaataaaaa tcagataatc cccgtgagcc
    11401 tgcttcatcc catcatttcg tgcttgcgac aatccttcgt tctttttatg aagcactgac
    11461 accctgtcat cttgttcagc gattgagtca cacaagcgac cactttcatc tgttgcacca
    11521 tcatcaacaa gaataatttc cagattttga tagatctgct tctgaatgga agctatcgat
    11581 ttttctaggt actgcgccac attatagact ggcacaatca cactaattaa tgcagtttcc
    11641 atgctactcc tctaatagtt tttctacttg ttcgatttgt tttgtaattg taaattgttg
    11701 aatgaattgg ctagcctcat cgacatcaaa gtttgaggca gaagtcatgt aattagtaat
    11761 cgcctgagct gcctcttgat tgctctcaat gatttgtcca aatcgtcctt cttgggataa
    11821 ttcctcagcc cctccaacgt ccgtagagat aaaagggagt cccagactca aggcctccac
    11881 atacactcca ggaaaacctt cttgtttaga catagacaag agaactttcg tctgagataa
    11941 atactgataa ggattttttt gataaccaag gaaatgtaca tagtcctcaa tcccatactc
    12001 tttgactcgt tttttcagtt cctcttccat atcaccagcc ccgataaaat agagatgata
    12061 gttttttccc tcttggtgta ataatcgtat cacttccact acacggtcag aacccttatt
    12121 ttcctcaatc cgtccgatag tacagatact ttgaggagca atctcgatat cgatcttctc
    12181 ttgagatttt tctagaatag tctgaaaatc atatccattg tagattatct gtaatttaga
    12241 agcataatct ggataaactt ccttgataga attgctggtc ttttttgaaa tccctacaat
    12301 tgtattcgca gcatccaact ggcttctatg tgattctctt ttagagctat ccttaagaag
    12361 ttcttcaata cttccatgaa tccaagatat cttcttgact tctcttcttt tagagaacaa
    12421 cagtggtgga ttcataatgg taaaagaaac ttcaacatca taatcatctt ttacaagcaa
    12481 acgacgagtc agtcttggaa aataaattct cattctccac aaaaaagctc gtaaccatct
    12541 ggtttggcga taatcttgaa gggattttaa aatgcgtaca tgctttggaa cagattcata
    12601 tcccttgtca aagtgctcca tttcaagaat atcaatatca tacttttcta gatccagatt
    12661 tgaaacaatg gttgatagaa tcttctctgc accacctcca agagaaaaag accacataaa
    12721 aaataagatt tttttcttag ccaccatatt ctcccttgta ttctgtataa gacttatcca
    12781 tatcagcgat gacagcatca tgatgcggta cctgcttgtc tgctggtgga ggcgtcatat
    12841 aatccccaaa agcagttctg agatagacat catagccgat tggaataggc atctctgttc
    12901 cttcaaatgg caagaaaaga ttgtcttcaa aagatgtgat tgggtacttg tttctcatgt
    12961 agccaggacc tgagcataat tctgtaatgc catcacaatc agccaaatca tacttagtca
    13021 tttctttctc agcttttttc cagatgcgat aacggagaga ttttggagtc aaacccagta
    13081 aaatgcgact tccccatttc atgagagcac catgcttttc tggaatagtt tgcgcacaaa
    13141 agagtgaata aatcaaggcc caacgaacct gttttttccg ctcagctgga tttttcggat
    13201 aataatccaa aggcaaaaca tccaaggtca gaccatgtgg caaatctaaa tcctgctgat
    13261 aaggcttgat acaggtggtt tccttgtcac gaatggtaat aaaaagatta cgatcaacaa
    13321 aatccttgtg actctttgac aagaaataac gttcatctgc ataacgaggc cataattctg
    13381 ctaatttctc ataatcttta cgaggcataa aaaagtctag gtcgtcgtcc caaggaataa
    13441 atcccttgtt tcgaagggca ccaatagcgc ctccgccaca gagataacag agcaaatcat
    13501 gttctttaca aaaggccaca aaatattcag ccatctccag actacgagcc tgaattgctt
    13561 ttaaatcagt catattgttc attattcttt ctatcgtatc gtttcattat accacaaaca
    13621 aggggtgaaa atctattgca gactgtaaaa aatcaaagcc tgactgctat ccaaatagct
    13681 atcaaacttt gatttttctg tcttatactc ttcgaaaatc tcttcaaacc acgtcagctt
    13741 caccttgccg taggtatagg taactgactt cgtcagtctt atctacaacc tcaaaactgt
    13801 gtttttagca gcctgcggct agcttcctag tttgcacttt aattttcatt gagtattatc
    13861 ttatctcaag cccatttgag cgagcttggt ttgatatttg ttttgatcaa ccagcaagcc
    13921 caagcctcca taaacatcat aggcatctac ccagtcaccc agttctggaa tcgtcaattt
    13981 ttcaatacca ttttttgctc catccaaaac agataaaccg tttgttagga ggaaagtata
    14041 gggtacgttg gttgaggtca tagcaaaaac ctttccaaga gcttcagaac cagtgaaaag
    14101 tttagtggga tctttaattt gctctaaaat tgctgttaaa acttgttgct gtctttttgt
    14161 acggccgtaa tccgcctcat catcatcacg gaaacgagca taattgagca gggtcgagcc
    14221 attcatctgc tgttttccga ctttaatggt ttgggttgga gactcagtct cggtagcgta
    14281 taaatcatct ccgactgtag cttctgttag gggacgccca ttcaatgttg aaaattgagc
    14341 atcaatcgtc accccatcag ggaaaagcgt gtcaatcgct gtggcaaagg cctggaaatc
    14401 aaccaaggcg tagtacttaa tgtccaagtc aaaattatct ttcaagactt ggcgaaccat
    14461 ttctgcccct ttttgcccct cttgttctcc taactcgtag gctacgttta acttgttatc
    14521 tgtctgtttt ctaccattaa tcacttgact ataaccatct atatagacca aattatcacg
    14581 catgaaactg actagcttca ttttcttatc tgagcccccg acatttaata ccataataga
    14641 gtcagttcgt gtctcaacac tgttctggcc gattcgacca tcagtaccca tgattaaaat
    14701 attaactcca tctctagtgt cctgaccatt aaagacttct acttgagctg cccgggcatc
    14761 agcagttttc tttgcgctag catcttggta accacgcaaa aacatgaata ccatggccaa
    14821 agccacacag accaaaagtg aaaaaatcac cataaaaatt cgtttaagac ggagcttccg
    14881 tcttttcttt tttggaggga aagagagtgc ttgtgatttg gattgtgagc gactccggtt
    14941 cgcatagctt ggtaagtcaa cctgctcttc tctttcttgt tccaagctag agctactatt
    15001 tcccctagca agagttagct tttcttgcaa ataggcaaac tcattttttt ctctctcatt
    15061 gagatagtga atatttttta gcaaataatc ataacgcaac tgctcatgat gacttaaggg
    15121 attttcttta ctcatcttct ctcctttcca tggtctgata ttggataaat aggataggca
    15181 cccagaattt tatactggat tccaatcgct tctaattctt tttgggcaaa gtggaccaag
    15241 tccttatcga tataatccac atcgataatg aaaaagtatt cacccagtgc tgtcttgagt
    15301 ggacgacttt caatttttgt caagtcaatt cctcgccaag caaaggtcga cagggcctta
    15361 taaagtgcac ctggaaggtt gtcaggtaat gtcaaggcca aactcatctt ttcagtttgt
    15421 gcttgcaagg gaatactagg cttttcagct cctagaaccc agaaacgtgt gaaattggct
    15481 tccatttcct gaatatcctc ggcaatcagt tccaatccat attcttcagc agaacttcta
    15541 ggtgcaactg ctgcaaaggg ctggtctgga tgttcggaaa taaaacgggc cgcataagct
    15601 gtactagctg ttacctcgat ttgagcctct ggatattgtt catcgatgaa tttctttcct
    15661 tgagccaagg cctgtggatg tgaaaaaatc ttttcaatct tagtatggcc tggaaccacc
    15721 atcaactgct gatgaatagg ctgaacgatt tctgctactg cttggatgtg agcctgatga
    15781 aaaagatagt ccaaggtttc atgaacacta ccctcaatag aattttcaac tggcaccaca
    15841 gaatagtcca ctaatccttg ctcataagcc ttgatgacat ctgtaatgtt ggcaaaagcc
    15901 tgcaattcct catgaggaaa agctgtctgc acaacgtggt gtgaaaatga tcccttggga
    15961 cctagataag ctattttcat cttagttcct ctataatttc ctctgggctt agcttggtca
    16021 catccaaaac ccgactagcc acttcctcat accaagcctg tctttcttga aaaatagcta
    16081 ctagttcttc cttgctatta tttagaaaaa gcggtcgctg attgtcctta tcagctgcga
    16141 tacgtaggta gagggtttca aaatctgctt tcaggtagat gttatctgta ttagtcttga
    16201 gtaagtcacg atttctctga gaaataacca ctcctcctcc agttgacacg acttggtctg
    16261 tttgtagtaa atcagctagg acttctgatt ctacatgacg aaaggctgct tctccctttt
    16321 cagcgaaaaa attcgcaatg gacataccta ggcgcttctc aatcagagca tccatatcaa
    16381 ggtaattagg gtccaagcct cttgcaatag tcgattttcc agcccccata aaccctaata
    16441 acaccttagc catgaatcaa gctctccaaa tcatcaaaga aactaggata gctggtattg
    16501 atggcttctg cacggtcaag ctccacctct ccatctgcaa ccaagagggc tgcgatagct
    16561 gtcatcatgc cgatacggtg gtcaccaaac gtattgactc tagcaccgtg aagagctgat
    16621 ttccctttga taatcatccc atctgccgta ggagtaatat ctgctcccat actatttaag
    16681 gcgtctgcca caacctgaat acggtctgtt tccttgacct tgagctcctc agcatccttg
    16741 ataactgtta caccttgggc ttgagtcgca agcagggcaa taatgggcaa ttcatcaatc
    16801 aatcgtggaa tcaaagcgcc accaatctct gttcctttca agtcagaaga ctcaacaatc
    16861 aaggtagcag atttagcgac tggatcgatt tcagttattt ccaattttcc acccatggca
    16921 cgaatgacat caataatacc ggtgcgagtt tcgttgatcc ccacattctg cagcactaga
    16981 cgagaatttg gagcaatcaa acctgcgact aaccaaaagg ctgcactgga aatatctcct
    17041 ggtacgacca ccttctgtcc tgtcaatttt tgtggcccct ggactgtgat tttcttacca
    17101 tccacactta aatgaccacc aaattgttgc aacatatctt cagtatgatt acgggtgtac
    17161 tctttttcga taataactga ctccccctta gcttgtaagg ctgcaaacat caaggctgac
    17221 ttgacttggg cagaggcaat tggcaactca taatgaatag gtcttaggtt tttcgtccct
    17281 tttaagcgaa ggggaggcaa gtctcgttca gtttgccctg aaatgctgac gcccattttt
    17341 ttcagtggaa gggtcacacg gtccatagga cgtttggaaa gactatcatc tccaaacatc
    17401 tctacttcga aatctgcacc agcaaggaca cctgaaatca ggcgaatcga ggtgccagaa
    17461 tttcccatat taagggcatt ttgtggcgct tttaagccag ccatgcctac accttgaatg
    17521 gtaataaccc catctttatc ctcaatttca acaccaaggt cacgaaaaac ctgcatggtc
    17581 gaaagaacgt cttcacctcg cagaatatca taaaccttgg tctcaccctc agccaaactt
    17641 ccaaagataa tggaacggtg gctgatagac ttgtcacctg ggacgcggat actaccatgt
    17701 aaatggcgaa tgtttgtttt tagtttcata ctggacctca tacttgcaat acttttacct
    17761 attttatcat aaaaagtcag aaattcctta aaaattcctg actttaggat cgttcttttc
    17821 ttatttcagc aattctgaaa ctggttcaaa aacaattttt tcaatgtcag aaaggtaaat
    17881 ggccaattgt tgttgcttgg taaagaattc tgacaagagg ctatttcctt gaatctgttt
    17941 accaaagcct tccatcttag cttggaagga cgcatctggc atttgacctg tctgtgctag
    18001 tttttgaatt tcctcttgaa aggcaagata ttctgtaaag attttgcttg cctcagcatc
    18061 tgctgcaatc gcatctttag ctgctttaac agccttgtat tctggtaatc cgcgtagacc
    18121 gcgactgagt tcgtttgcac tatcgtaaat atttgacatg ttcttctcct tatttgatga
    18181 cgactgtata gtcggtattt tctgttatga gatgctcagc tctttccaag tcttgagcat
    18241 ttttaaatga aatttgtagg attccgtgaa tatcctcacg attttcctcg ttgatgtgga
    18301 tgttaaccaa ggaagttcca cgtagcagtt ccaaaatccg caggatgaca tcttcttcat
    18361 caggaacgtc aacatagagg tcgtaagagc tatccacacc accacgctta tggatttcca
    18421 tggtctggcg ttgttcacgc gcttggttaa aaaagttcca aatttgctct tcatctccct
    18481 tactaatggc ctgaccaatc acttccaaac gttccttgaa atcctcaatt ctatccagaa
    18541 tggtctcgct attggacaag agaatggagg tccacattcc tggctcgctt tccgcaattc
    18601 gggtcatatc tcgaaaacca cctgccgcaa agcgccttgc catctcatgc tcttgagcat
    18661 agaccgcagt ctgctccatg agactagaag ccaaaatatg aggaaaatgg ctaatctgag
    18721 aagtgacacg atcatgctcc ttggcatcaa tctcgataaa acgagcatga agacctgaaa
    18781 gcagatcctt catttcctta agcgtgtcct gacttgtcag gcttgaaggt gtaaagatat
    18841 aataggcatt ttcaaaaaga ttgacatctg ccgaagcagc ccctgtcttg tgactaccag
    18901 ccatgggatg ggccccgaca aagcgaacag acttgccagc caaatactgc tccgccgcat
    18961 ccacaatggt tgacttggtc gaaccagcat ctgaaataat aacgccttct cgcaaatcca
    19021 aattggccaa ctccttaatg aaagcaatag tttgtttgat tggcaagctg aggataatga
    19081 catctgccaa aggagcaaaa ctagcaaaat catccgttgc acggtcaatc ataccttctt
    19141 tcaaggcgat atctctcgaa gcttgactac gattataacc taaaatttca taatctggat
    19201 gatcgcgttt gataccaagt gccatagagg ctccaatcaa cccaagacct gcgatataga
    19261 ttgtttttgc cataggaact ccttaatagt tctttgtata gtctcggtgt ttggctaccg
    19321 cttcttttag ttcctcaaga ttatctgatg agaatttttc gaggatttct tgcgccagaa
    19381 ccgttgctac aactgcttcc atgaccattc ctgcagctgg aagagcagtc ggatcacttc
    19441 tctccacggt tgccttgtaa ggttcgtggg tttcgatatc cacactcata agaggtttat
    19501 aaagagtagg aatgggtttc atgaccccac gaacaacgat gggttgccca ttagtcatac
    19561 caccttcaaa accacctaga ttattggtac ggcgagtata accgtcttct ttagaccaga
    19621 gaatttcatc cataacttgg ctgcctttac gataaccagc ctcaaagcca agaccaaatt
    19681 ccaccccttt aaaggcattg atagagacaa cagcttgagc caatcttgca tccaattttc
    19741 tatcccattg gacataggaa ccaagaccaa ctggaacgcc tccgacgact gtctccacaa
    19801 ccccaccgat ggtatcacca tcacgtttga tttggtcaat atagtccttg atttcctgtt
    19861 ctcgttcttg gttgacaata gaaacttcag actgggcagc tctttgctta atttcagcga
    19921 ctgtcagatt ttcaggaaca tctatttcct taccaccaaa gaccacgaca tggttggcaa
    19981 tctccatatc cagctcagcc aagaggcgtt tggctactgc accaactgcc acccgcatgg
    20041 tggtttcacg agctgatgaa cgctccaaag aatttcgcaa atcatcaaaa cggtacttaa
    20101 tccccccaac caaatcggca tgacctgggc gaggatgagt aattttccgc ttgcttttaa
    20161 ggcggtcttc aatgtcctcc gcagacatga tgtccagcca tttctggtgg tccttattga
    20221 tgacatccat agtaataggc gcccctgtcg tcttcccgtg gcgaacaccc gaagtaaaga
    20281 caacctggtc actctcaatc ttcatacgac caccacgacc gtagccaccc tgacggcgtc
    20341 taagatcctc attgatatcc tcagctgtca atggaagtcc agctggaatt ccctcaataa
    20401 tagctgttag acgggggccg tgtgattctc ctgcagttaa atatctcata cactctcctt
    20461 attttaccaa gtagtctttc atctcttcca gagaaactgg gtgaatggtc gctgaaccaa
    20521 gctctggcac caagaccaat ttcaaggtgt taccacgcgc tttcttgtca tgagtaagag
    20581 cctgataaag cttgtcaact ttccaatttt catagtcaac aggcaagccg aatttctgac
    20641 acatctctgt gatagattgg gtaatgccag ctggcatgag gcctttttcc tcagcaacct
    20701 tggaaatctg taccattccc atggcaacag cctctccatg catgaccttg ccataaccgg
    20761 cagtcgcttc gatggcatgg ccaatagtgt ggccaaaatt gaggtaaaga cgaataccat
    20821 tgtccaactc atcttcaacc accatcttgc gcttcacctg acaagaatgt tcaatcaagg
    20881 tctctgcatg ttccaaaata ctctcaacag aaccattcag tcccgtcaag agagcccaca
    20941 gttctggatc ctcaatcaag ccatacttga taacttcacc catcccttca atcaactctc
    21001 tttttccgag ggtttcaaga acaagtggat caatcagaac cccatctggt tgggcaaagg
    21061 tccccaccat atttttagca aatggtgtgt taacgcctgt ctttccaccg atagaagaat
    21121 caacctgagc tgtcaaacta gtcggaatct gaacaaagtg aataccccgc atataggtag
    21181 aggctacaaa gccagccagg tccccaacaa cgccaccacc aagagcaacg attccatcgc
    21241 tacgagtcag accttgcttg actagaaatt catagacttt ctgaacagta gttaaattct
    21301 ttctttcttc accttctaag aaatcaaaaa cagctacctg aaaaccagca tcttctaggc
    21361 tgagcttgac cttctctgca tagagagagg ctacatggtt atctgtcaca atgactacct
    21421 tttgcggttg ccagagttct cgcaaccact gaccagcctg ggccatacaa cctttttcaa
    21481 tctgaatatc ataaggatga tgaggaatat cgattctgat tttcatagga gagtctccct
    21541 ttctttattg atatttttct gttaaagact gccaaatctc ttctgtcggc attttcttgc
    21601 ctgtccacag ttgaaaagct tctgcagctt gatagagcaa cattcccaga ccattgactg
    21661 ctggattgcc ctgacttcta gcccatttca aaaacggtgt ttcaaagggt tggtatatga
    21721 tatctgcaac taagagagtt tctggtaaga ctatgttttc aggaacagga gaggattggc
    21781 catccatgcc cacactggtg gcattaacta gcaaatccga ctcggcaatc cttgcttgca
    21841 gttcagaaac atattctaaa gcacacaaat ccactttaaa gcctgtctgc tcctgtaact
    21901 tgtctaggta aggtcttgtt ttttccatag aaacggaacg aacaaagacc gaaatctgac
    21961 tgacgccatc caaaatagcc tgtgccaaga ttgatttagc cgcaccacct gcacccagca
    22021 gggtcatctt tttacctgaa attgtaaaag aaggcaagca cttaaaaaat cccttgccat
    22081 ctgtattata tccaattaaa ttgccattct cattgacaac cgtattaacc gcaccaatca
    22141 agcgcgcttc atcgctcagc tcatccaaat aaggaatcac ctgctcctta tagggcatgg
    22201 acagattgat gccaaacatc tggtagcgac gaatattggc cactgtttct accaagtcac
    22261 tcgcttcaat ctcccaagcc acataagcac cgttggtagc tgtcgcctca aaggctctat
    22321 tgtggatgaa gggagaaata gaatgcttaa taggattggc aacaactgca gctaaacgtg
    22381 tatagccatc aagcttcatc caaaatctcc ctgatttttt tcatgctagc tagagaaatc
    22441 tgcccagggg cactaacctc atccagactg gcaaaagacc aactcgaacc agtcacatcc
    22501 gcagtgatac gagagacctt gcccacctta cccatagaaa tggtcacata ttcctgttca
    22561 ggattgagcg ttttaaagcc tcgtgtatag ttcatcaagt ctaagacatc ctgctccgtg
    22621 tgagccatca ccgcaacctt aacaagtttt ggatttagga tcgtcaactc tgacaagatt
    22681 tccatcatgt tctcaggtgt ttcttggaaa ttatggtaac tcaaaacaag atttgggaag
    22741 tccagcattt cctcaaaaac atccttgtag ctatagtact caaaatcaat atagtctggt
    22801 tgatagagtt gcgcaacttc cttgattaga tggatatact cttctggaga aaggtcgatt
    22861 tctccacctt cggagcgagt tcgtagcgtg aaaaccaact cacggcctgc gaatttttca
    22921 aaaatggctg gagctacctg caaaatcgct tctttaggca gatagtcggc acgccattca
    22981 atgatgtcgg catccaggta cctcgtggca tccagagcct gagcctcctc taaacttctt
    23041 ggcattactg aaacgattaa tttcatttac taaccttcat actaatcacc ttgaggtaat
    23101 tactactttc atctttttta ttataggcaa aatctgctgg aagaccatat ttgtttaaaa
    23161 tctggtaact tcttcctgca aagcctttat caatttgttc tgtaaatttc tgacgggaaa
    23221 cattggcagc attggtactg gcaatgataa tccctcccgg atttaaaatc tcaagactct
    23281 gggaaatcaa cttgtgataa tccttggcca cagagaaagt ttgtttttta ttccgagcaa
    23341 agctaggcgg atctaggaca atcacatcgt aggtcaagtt tttgcgtttg gcatatttga
    23401 aatactcaaa gacatccatg actataaaac gacgctcgtc tgtgctgagc ccatttgcct
    23461 gaaaatgcgc ttgagacaat tctcgtgaac gtttggctag atcaacagaa gttgtctggc
    23521 tagctcctcc catggccgca gctactgaaa aagccgctgt gtaggaaaac atattgagca
    23581 aggatttacc catagccaag ccgtcaacta aactaccgcg aacctcatgc tggtctagga
    23641 aaattcctgt catcaagcca tcattcataa agacttgata caggacacca ttttctaaaa
    23701 cagtgaaaaa gtcaggtgct tcttgaccat aaacatgggc agattcatag tccaaaccct
    23761 taaagcggat tttctcataa gcccctaaaa cctcagggaa aacctgtcta aaggcttctg
    23821 atatagtctg acgaatctga taaacataag agttatacca agaaaagacg gcgtagtcgc
    23881 cataaaggtc cactgtcaga cccccaaagc catctccctc ttgattaaag agacgaaagg
    23941 cagttgtcaa atcatcttga tagtaggcgt ttctcttttc tttggctttt ctaaacaacg
    24001 tttcaaagaa agcttgattg aaggccacct tgtctttgct gacaaaccag cccaagccct
    24061 tgttttgctg agaaaggtag gcagtcccaa gaaagtttcc ttcctgaccc tgcacctcta
    24121 cttcctgatc cttaagattg acattctcaa gatcactggc ttctagtaaa actagcccct
    24181 tagcaagctt cttttcaacc cttttgctga ctcttattct attcataact accattatat
    24241 caaactttta gacaattctc aaaaaagaaa ctacccttgc ttttttactc ttcttttaaa
    24301 aaatggtata ctagacttcc tgcaaaacta ggaagtaaat gtgtaagaat cacaataaaa
    24361 aatgctcttc cgtcttggag gagcatttct ttttatcaac gaaaatcaaa taacaaacta
    24421 tgaaactagc ctcaggttaa ctgtgagatt ataggtagag aggttgaatc agcaatatgt
    24481 gtctgtcaaa tttagtgaca aaggtagtag aagaaagatg aagaaataaa tctgcttcag
    24541 tagatatctg gaaaatttga ttttatagaa aagccttttg ttacaaactc aatatactat
    24601 caataaataa tattatagaa gcaacaataa ttaaaatttc acctatttgc atcattctat
    24661 ttcgaactct aaatatatgt tctatcaaaa atacttggat cacacacatt ataggaatta
    24721 acgtttttga aattgaaaaa tatcccaata aataaactat aaacaacaat aatagaacta
    24781 tattatattt cttattcaaa acattcctcc ctatattttt gattaccaat cttaatcatt
    24841 tacaactaca ttctaacaaa ctataaaagc gtttgtcgaa ttgaatttat caagcaagca
    24901 accaactatc tcatcttttt tctatttctg ccaatatgcg tgacaggtaa taatgatagc
    24961 caaaaatagc aagagcaagc aagacgataa gagctcctac tcccaagttg atggcaagga
    25021 taggggagag agactgaacc aagaatatgc tcccaattac aagggccatc aggattgcac
    25081 tataaataaa caataaaact atggcgacta tgccatttga acgattcacc aggtccgtaa
    25141 tgctactcca attggttgac agatttttaa cgtccttaaa gtaatggtgg caagaaagga
    25201 tgacactggc aatgatccag actacaagaa ggtaaatcat cgaaaggatg gacaagccta
    25261 gatatagaga aagaccgagc aaagtcagaa ctggtaaaaa ggactgaaca gcaaagataa
    25321 tccaaaattt cactttcaca taacgagcaa agtcaaaggg taaactcttc agaaaatcaa
    25381 cattttccct ctccaaggac aaggcaattg aatgcaggct ggtgatattg ttattgacaa
    25441 ctgctataaa cactcctaca aaaaacaagg gtaaccagta tggaggatga atgtctggaa
    25501 ctatctgaga atctcggatt ttggaaatca gactgatcat catgagataa ggaaggaaag
    25561 cacttgtaaa aagcactgta atcacaccag tcccctatcc caagagggtg aggtggtagc
    25621 gtaaaaccat acggaaaaag ccctttttag tagttgaaat cctctccttg ctgcgacgtt
    25681 cttttttgac cttctcctca ctgttaagca ggatcacgtc ataaaaacga ggaaggacct
    25741 tctttttggt cagataaagc aggaagagag ttagtcctat ccaagcgagc agacccacta
    25801 aggcttctgt cgaaaaaggc tccactgcta ttttgtaaaa gatatgaaga ggataaagga
    25861 gaaatggaat gtctctaact ttgtcaacaa tacttccaaa agtcgactga agaaagaaga
    25921 taaatattaa aggtatgaga actcctatcc caatcatcac attcgaaaaa atagactgat
    25981 actttctgaa gaccctagtc tgagccaaga aatgtactgc cactaccgtc actaaagtaa
    26041 cagagacaaa taataaggtc aaggacagta gcatcaaagg caaacccagc caaagagaag
    26101 gagctagact aatatagagg gctagaaaat aagctaggat tggtacaatt ccagttagag
    26161 ctggcaagag gacagacaga cctttggcca ttataatctc tgattcttta aaggcatagg
    26221 gcctatagga ggccaggtcc ttactctcat aaaagacatt gtaaaaggca gtgaaagaag
    26281 ttgaaaaggc cagcaccagt aaaatagcaa ccatcgagct aaaataaata ggtatttcct
    26341 caaaaggaaa atgaatggct atattactaa aacagatgag catcaagaga ctggaaaaaa
    26401 tgtaagaact taggactcta gcagaaacat ttactttttt cccaggattc ttagcctgct
    26461 tctttcgtag attagccaga ttagcttctt gagatgaata gaggatattg atatcaacta
    26521 attttttaat gaccttgaga cgcatccgca acctcctctt ttctaccagc aagactaagg
    26581 tagatacttt ccaaaaactg gtctgggtgg tctttcctca agttctctac actaccacaa
    26641 tagatcaaat gccccttttt caaaatagca atccgatcac agacttgctc ggctacctca
    26701 aggacatgag ttgaaaacaa gaccgtcttg cctttttgtg catgttcctt catcatttgc
    26761 ttcaaatcaa aggcggcctg gggatccaaa ccagtcaagg gttcgtccaa aacccaaata
    26821 tcaggagcag acaagagtgc cccaatgaca aagactttct gacgcattcc gtgagaaaga
    26881 gtttcaataa cctgatagcg gttttcagca aaatcaaaaa cgttcaatag cctagctaga
    26941 ctagtctcca agtcagagct agtcagatca taggatgaag cgatcaattc ccaaaattca
    27001 ttggccgtta agcgtaaaaa taagtcaggc gagtctgcta cgtagccaat ctttcgtttg
    27061 atcgccaagc gattttccga taactcctga ccgtctacca aaatacgacc actgctgggt
    27121 gaaatgatac tgactaggga ttttatggtg gtcgattttc cagccccatt atgaccaatc
    27181 aagcccataa tctctccatt ttcaatctgc aaattgagat tactcaaggc ctctttatca
    27241 ccatacaact tactaacatt ttgaaattca atcatgggac aactcctatc tttatctgta
    27301 ttatacatcg ctatactagc actttgatac aaaaaaatca atactttatt ttaagtagtt
    27361 aaaatagttt ccttctatct tacgcaaacg tttgcgccga gagatacttt atgatagaat
    27421 aaagaacaag attgacaagt aagaggaaac atcatgcaaa atcaaacact catgcaatac
    27481 tttgaatggt atctgcccca cgacggtcaa cactggacgc gtctggctga aaatgctcca
    27541 cacctagctc atctggggat cagtcacgtc tggatgccac cagccttcaa ggcaaccaac
    27601 gaaaaagatg tcggctatgg ggtctatgac ttatttgact taggagagtt caaccaaaaa
    27661 gggactgtcc gcaccaagta tggtttcaaa gaagactatc ttcaagccat tcaagccctt
    27721 aaagaacagg gaattcaacc tatggccgat gtagttctca accacaaggc tgctgccgat
    27781 aacagggaag cctttcaggt tatcgaagtt gatcctgtag accgtacagt tgaacttgga
    27841 gaacccttca ccatcaatgg ctggactagt tttaccttcg atggtcgcca agatacctat
    27901 aatggcttcc actggcattg gtaccacttc accggtacag actacgatgc caaacgcagt
    27961 aaatctggga tttatctgat ccaaggggac aacaagggct gggctaacga ggaattggtc
    28021 gataacgaaa acggaaacta cgactacctc atgtatgccg acctagactt taaacatcct
    28081 gaagtcatcc aaaacatcta tgactgggct gattggttca tggaaacgac tggtgtagct
    28141 ggtttccgtt tggatgccgt taagcatatt gactctttct ttatgcgcaa cttcatccgc
    28201 gatatgaagg aaaaatacgg tgacgatttc tatgtttttg gtgaattttg gaacccagac
    28261 aaggaagcca atctggacta tctcgaaaaa acggaagaac actttgacct tgtcgatgtt
    28321 cgtctccacc agaatctctt tgaagccagt caagctggcg caaactatga ccttcgtggc
    28381 attttcacag atagcctggt tgaactcaag cctgacaagg ctgtgacttt tgtcgacaac
    28441 cacgataccc aacgaggaca agcccttgag tctaccgttg aagaatggtt caagccagca
    28501 gcctatgccc tcattttgtt acgccaagac ggccttccat gtgtctttta cggagactac
    28561 tatgggattt caggccagta tgctcaagaa gatttcaaag aaatccttga ccgcctccta
    28621 gccatccgaa aagacttggc ctatggagaa caaaatgact actttgacca tgctaactgt
    28681 atcggttggg tacgttcagg tgctgaaaat caatccccaa tcgcagtcct tatctcaaat
    28741 gaccaagaaa acagcaagtc aatgtttgtc ggtcaagaat ggactaatca aacctttgta
    28801 gatttacttg gtaaccacca aggtcaagtt acaattgatg aggaaggtta tggacaattc
    28861 cctgtctcag ctagatccgt aagtgtctgg gcagtcaata ccatctaata gctcataata
    28921 accaagctag gtccaagcgg atttggcttt tttgtattca caaaaagacc tacccaaatg
    28981 gatagatctt tacttgatta caatttacct gctactgcat ccaacaattc ttggatctta
    29041 gcttggttgc ttcctcctgc catggccatg tctggtttac caccaccacg tccatcgatg
    29101 attggtgcta attctttgac aaggtttcct gcatgaaggt cttttgtctt gcttgctaca
    29161 aggacattga ctttgtcacc gatagcggca actaggacaa gaagatcaga gtagtctttt
    29221 tgtttccagt tatctgcaaa agtacgaagg gcaccggcat cggatacaga cacttgacta
    29281 gcaatgtaac gatgaccgtt gacttcctta gcatctttga agatatcgcc tgcggctgca
    29341 gctgcggctt tttctttcaa ctcagcattt tctttttgaa gttgacgaag ttgttcttga
    29401 agtccttcta ccttgtgagg tacttccttg acttgaggtg ctttcaaggt tgctgcgaca
    29461 gctttaagag catcctcttg ttcacgatag gcttcaaagg cttccttacc agtcactgcc
    29521 aagatacggc gagttcctga accgattcct tcttctttga caattttgaa gagaccaatc
    29581 tcagaagtgt tgccaacatg agtaccacca caaagttcaa tagagtagtc accgatagtc
    29641 acgacacgaa cttccttgcc gtatttctca ccaaagaggg ccatagctcc catttcttta
    29701 gcagtgtcaa tatccgtttc aactgtcttc acttcaagtg cttcccaaat tttctcgtta
    29761 acttgctgtt caatcgcacg aagttcctca gcagttactg cttggaagtg ggtaaagtca
    29821 aagcgaagga attcaacttc gttaagagat cctgcctgtg ttgcgtggtt tccaaggata
    29881 ttgtgaaggg cagcgtgaag caaatgagtc gcagtgtggt ttttcatgac acggtgacgg
    29941 cgattgctat caattgccaa ggtatattct tggttcaagg caagcggtgc aaggacttca
    30001 actgtatgaa gggcttgacc atttggggct ttctgaacat tggtcacagt agccacaatc
    30061 ttacctgact catccaagat ttgtccgtag tcagctacct gtccacccat ttcagcataa
    30121 aatgacgttt ccgcaaagat aagagaggca gttccttctg aaacagctcc tacttctgca
    30181 ttgtcagcaa cgatagctac caatttagaa gacaattggc tagtattgta gttgaagaca
    30241 ctttctacag tgatgttttg aagagtttca ttttgcatac ccattgagcc acccttgaca
    30301 gctgacgcac gcgcgcgttc ttgttgttct ttcatggctg cttcaaaacc ttcacggtct
    30361 acagtcatac cagcctcttc agcaatttct tcagtcaatt caactgggaa cccataagta
    30421 tcatagagtt tgaagacatc tgaaccagcg ataacagatt gacctttttc tttcaagtct
    30481 gctacaatgc cttgggcaaa gtgttgacct gagtgaaggg tacgggcaaa tgattcttct
    30541 tcgctcttaa cgattttctc aataaagtca cgtttctcaa gcacttctgg gtagtagctt
    30601 tccatgattt ttccaacagt tggaaccaat ttgtaaagga aaggctcgtt gattcccaat
    30661 ttttgaccat gcatagaagc acgacggaga agacgacgaa gaacataacc acgaccttca
    30721 tttcctggaa gggcaccatc accgatggca aatgaaagtg aacggatgtg gtcagcgatg
    30781 accttgaagc tcatgttgtc gccatcttgg tcataaacct taccagacaa tttctcgact
    30841 tcacggataa tcggcatgaa gaggtccgtt tcaaagttgg tcttagcccc ttggataacg
    30901 gccaccaaac gctccaaacc agcgcccgta tcaatgttct tatgtggcaa ttccttgtat
    30961 tcgctacgag gaacagcagg gtctgcgtta aattgtgaca aaacgatgtt ccagatttca
    31021 atataacggt cgttttcaat atcttctgca agcaggcgaa gaccgatatt ttctgggtca
    31081 aaggcttccc cacggtcaaa gaagatttct gtatctggtc cagaaggtcc cgcaccgatt
    31141 tcccagaagt tgtcctcaat tggaatcaag tgacttggat ccactcccac ttcaatccag
    31201 cggttgtaag aatctttatc gtctggatag taggtcatgt aaagtttttc agcagggaaa
    31261 tcaaaccatt cagggcttat caaaagctca taagcccaag tgatagcttc gtcacggaag
    31321 taatccccga tagagaagtt ccccaacatt tcaaacatgg tatggtgacg cgcagtcttc
    31381 cctacgtttt cgatgtcgtt ggtacggata gccttttggg cattggtaat acgtggattt
    31441 tcagggataa tggtcccgtc aaagtatttc ttaagggttg ctaccccaga gttgatccac
    31501 aaaagagttg ggtcatttac aggaaccaaa cttactgatg gttctactga gtgacctttg
    31561 gtcgcccaga aatcaagcca catttggcgt acttgtgcac tagatagttg tttcatattg
    31621 tctccttatt tacttgttta atgtgattgg ctttccagca tttccacata gtcaatcgcg
    31681 acacagaggg aaatgactag gtctgcataa gcgtcttcaa gaaccgttac ggtataggta
    31741 gaggtcagat ggaagagttc cttcttaatt tccgcaatca actgatcgcg atcatccagc
    31801 aatttgaaat tcaaatccca gatattgccc tcgatacgaa gacctagatt atcaaactca
    31861 tacttatctc gccaaaaggt caacttctta cgaatgacaa aactcgagcc atccagaagc
    31921 tgaatctcaa aacgaggaag caaggtcaag atttctttac tgatctgact gacttgttca
    31981 ccagccgcat catagatggt aaaagttttg ggaatcttaa aaaatgatcc ctccacctga
    32041 taggcaattt ctcccctgtc atccttgata gcgaagcgtt cgcctccaag acgaaacttt
    32101 tgtttgacaa gaaatgtttt catcaacacc tccaaaaatc aaaagacaag ctcatatcac
    32161 gaagggcgaa aaaccgcggt accaccttca ttcaatgaac ttgtcattct cttgttctta
    32221 tgcaattgta tgattgagta gcatgacttc ctagcttaga tggctcgcag caccgccatt
    32281 tctctggact aagacaagtg aaaatcaatt ctcaactttc ttattatatc gtttttttaa
    32341 tcttgcgtca actggaaatg atctccgttg aattagacca attccctaca tctctgatta
    32401 cttttccagg atatattttt tcttactgcc gtttttcttt ttatcccaaa ttttcatatt
    32461 actaaacaca gctactagaa tatttccaaa tataaaggtg cctatcaccc aatatatgga
    32521 ctcagttgtt aggtattgtc gatccaagcc atcctttaaa tggaatagta tagcagtttg
    32581 gttaacaatc ataaaggttg gccagaaact tttgttgaaa aaagtagaca ttttcattat
    32641 ttgttgccgc tttctgtaag gttaatactc aataaaaatc aaaaagcaaa ctaggaagct
    32701 agcctcaagc tgtacttgag tacggcaagg caacgctgac gtggtttgaa gagtataggc
    32761 ttagtatact actaggcaag caaataagca aataaacaac tagaatagaa aaagataggg
    32821 ctctaaaaac tgacttctat tccttaaaaa cgaaccagct tgactgattc gtcttcttac
    32881 gtttatctcc tacttccgat acattttaaa ctgtaggaag aggtcgctat atttccctgt
    32941 ccatttatgg tcaaatttct cataaatttc taggtgtttc atggtttcaa catcgggata
    33001 gaaggcctta tcttcctttg tttcctctgg gagcaattcc ttcgctggta tgtttggtgt
    33061 tgaatagccg acatactccg cattttggag agcattttca ggtttcaaca taaagttgat
    33121 aaaggcatag gctgagtctt ggtttttaac tgttttggga atgaccatat tgtcaaacca
    33181 aagattgctg gcctctgtcg gtaccacata acgtagattt tcattttttt ctaacatttg
    33241 gctggcttca ccagagaagg tcacgccgat tgcaacgtta ttctgaatca tatagccctt
    33301 catctcgtcc gcaacgatag ccttgatatt tggagtcagt ttgtagagct tatccactgt
    33361 ctcttccaac tgctgcagat ccttggagtt gaggctgtag ccgagggaat tgagtcctag
    33421 tcccagcacc tcacgcgccc catcaaagag catgatagaa ttcttatact ccggcttcca
    33481 aaggtcatcc caatgctcag gcgcttcatc taccatggtt tcgttgtaga caattcctaa
    33541 ggttccccag aagtaaggga tggagaattt attacctggg tcaaaggact ggttgagaaa
    33601 ctctggtccg atattttcga ttccttcaat ttttgaataa tcaagcggaa ccaagaggtc
    33661 ttcgtccttc atcttgttaa tcatgtattc acttggaatg gcaatatcgt aggtcgttcc
    33721 accctgcttt atcttagtgt acatggcttc gttggagtca aaagtctcgt actgaacttg
    33781 aattcctgtt tcttctgtaa actgagtcaa gagttcagga tcgatatagt ctccccagtt
    33841 atagataacc aatttttgac tatctcgact attgatttta ctatctaaat gagtcgcaat
    33901 tccccacaag acaaggataa tcgctgcaat tcctgctaaa aatgaataga tttttttcat
    33961 gcttgctcct ccttctcacg agagataaag taataaccta caactaggat aatactaaag
    34021 agaaagacta gagcagacag ggcattgatt tctaaggaaa tccccttgcg agcacgagag
    34081 taaatctcga ctgatagggt tgaaaagcca tttcctgtta caaagaaggt cacggcaaag
    34141 tcatctaacg aataggtgaa ggccatgaaa taaccagtaa tgatagacgg agtcaggtaa
    34201 ggaagcatga tttccttgaa catctgaaat tgactagctc ccaagtcata ggccgcatga
    34261 atcatgtcgc cattcatttc cttgagtcga ggcaagacca tcaagaccac gataggaatg
    34321 gagaaggcca cgtgactaga tagaacggtc aaaaagccaa gtgaaaactt gagttgggta
    34381 aagagaatca agaagctagc accaatcata acgtcaggcg caaccatgag gatattattg
    34441 agtgatagaa aggcttcttg gtatttctta cgagactggt agatgtaaat ggcaccaaaa
    34501 gtcccgataa tggtcgctat caaggctgat aggaaggcca agaaaaatgt ctgagccaaa
    34561 atcagcatga gtctcccatc tccaaacatg gtttcaaagt gagtccagct aaaacctgta
    34621 aagctattca tatcatcacc agcattaaag gcatagccaa tcaagtaaaa gataggcagg
    34681 tagaggacca gaaagaccag tcccagataa aggttggcaa attttttcat cgttctctcc
    34741 tttccttagt cacccacatg gtgatgaaca tggtcaggat gagaatcaca ccgatggttg
    34801 aacccatacc atagttgtca ttggttagaa aattctgctc aatagccgtc cccaaggtga
    34861 taacgcggtt cccaccaatc aaacgggtca gcatgaagag actcaaactt gggataaaga
    34921 ccgactgaac cccacttcgc acaccgttca tagatagagg gaagatgaca tgacggaagg
    34981 tctcccactt agttgcacca aggtcataac tagcattgat gagattatta tccatgtcgt
    35041 ctaagacatt gaaaatcggc aaaatcataa aggggagctc gatgtagctt gcgacaaaga
    35101 taaaggaaaa atcggtaaaa agcaactgtt gtgaaccaat tccgataaat tccaagaatt
    35161 ggttaataga gccattttga ccaaaaatcc cgataaaagc ataggcttta aggagcaaat
    35221 tgatccaggt aggaaggata atcagcatga gccagagttg acggtgcttg agacgggtca
    35281 aaaagagggc tgttggatag ctgataagca aggtcacaaa ggtcacaatc cctgcataaa
    35341 gcactgagtt gaaactcatt ttgaggtagg tcaagttttg tgacgcaaag taagatttat
    35401 aattttctaa actaaactgg ccttcaatgt tgaaaaagga ttgtccgaaa atcaagacca
    35461 agggtgccaa tacaaagagg gcaatccaaa gcatgtaggg cactacaaag agtttagagc
    35521 ttgttttctt catctctttc ctcctcgatc gcattgatca gacctgcttc ttgctcttcg
    35581 atttccacgt attcttcgat acgagcatcg aactcttctt cggtttcatt gagacgcatg
    35641 atgtggatgt cttctgattc aaagtccaga ccgatttcct cacccacgat ggccttacgg
    35701 gttgagtgga tcatccattc atttccaagt tcgtcatagg cgataatttc ataatgaact
    35761 ccacggaaga gctgggtgtc gaccttaact tggagtttgc cttcttcagg aagggtaatg
    35821 cgcaagtcct ctggacgaat aacgacctca acaggttcat ttggcttcat cccaccatca
    35881 accgcttcaa agcgtttgcc gttaaattcg accaagtagt cctcaatcat ggtacctggc
    35941 aagatgtttg actccccgat aaaggtggca acaaagtggt tgattggctc atcgtagatg
    36001 tccacagggg ttccagactg gacaatctcg ccatcattca taacgaaaat ccagtcactc
    36061 atggcaagag cttcttcctg atcgtgagtg acaaagacaa aggtaatgcc caatcgttgt
    36121 tgtaattcac gcaattcgta ctgcatgtct gttctcaatt tcaagtccag cgctgataaa
    36181 ggctcgtcca acaagaccac acggggttgg ttgatgatag cacgggcgat ggccacacgc
    36241 tgacgttgtc ctccagaaag tttgcggatg gaacgttttt cataaccttc caactgaacc
    36301 atcttgagaa cttccgctac acgctgctcg atttctttct tatcaatttt acgcaagcga
    36361 agtggaaagg caacattttc aaacacattc atatgtggga acaaggcata ggattggaag
    36421 acggtatgta cgtcgcgctt gttggttgga atatcattga tacgaacacc gtctagcatg
    36481 atatctcctg tcgtcgcatc cagtaaacct gcaataatgt ttaggatagt tgatttcccc
    36541 gaaccagatg cacctagaag ggtgtagaat ttcccttctt ccaactcaaa gttgatgtct
    36601 ttgagaacct tggtgttgct gtcttcaaaa actttagaga cgtttttgaa ttcgataatt
    36661 ggttttttca attggcataa attccttctt tttcatagat taaccgatcg gggctctgtc
    36721 aggtccccac tacctcttgc agggagtaaa accacctgca tacatcttcg ctaccgatag
    36781 gctttcaccc aagatccgga cttctctttc aagcgtaata cctgagtgtt ccttgacttt
    36841 ttcgataacc gattggatca agtcctcgta gtctttggcc gttccatctg cgacattgat
    36901 cataaatcct gcatgctttt ctgacacttc tacgccaccg atacgatagc ctttcaagcc
    36961 agcttctgaa attaactgac ctgcaaaatg cccgactgga cgcttaaaga ccgagccaca
    37021 agatgggtat tccaaaggtt gcttgagttc acgtaggtgc gtcaagcggt ccatttcctg
    37081 cttgataacc tgatgggttc ctggagctag ggcaaattta actgacaaga caactgcacc
    37141 agactcctga atagctgaat ggcggtaacc aaaagccaag tctttagcag acagggtttc
    37201 gatttctcca tccttggtca agaccttaca agactgcaag atgtgagcaa tctcgccacc
    37261 ataggcaccc gcattcataa agacagcacc gccaacgctt cctggaatac cacaagcaaa
    37321 ctcaaagcca gttaaactat gacggagggc aatgcgagtt gtttcaatca agttagcccc
    37381 agcttctgct tcaatggtat agccatcaac agaaacgtta ttgagcttgt cacacaagat
    37441 gacaaatcca cgaatcccac catcacgaac gatgatattg cttgcattgc caagaaccat
    37501 ccaagggata ttttcttggt tggcaaattt cacaaggcga gccaactcaa aacgatttcg
    37561 tggaaagacc aaataatcag cctctccacc tacttttgta taactatagc tatgcaaggg
    37621 ttcctgaaaa cggatatcaa ttccttctaa gatttcaagc attttttctc ttacagacat
    37681 gtcactcttc cttttccaaa attcattcca ttataccatt tttagagaca tttgacgacc
    37741 ataaaaatac cttgtttgga ttttgcataa gaaaaagagg ttcccccctt tttatgattt
    37801 tttacaaaag atttccttgg ttccataggc gaccagaacg agctccagtg ctagaatcac
    37861 ttcaaccaag actggatttg tcaaccagcc tacttggaaa agagatggtg ccagatcaaa
    37921 gaaggcatgc aagccatagg ctgttaggag ataaatccat ttcttctggc gaacagcttg
    37981 gtaaacccaa actgtcaaaa gtaattggaa accaagcgcc aagattcgct caaaaccaag
    38041 caaataaatc tgccagaccg aaagtgactg aatggttttt aacatatttt cagacagtaa
    38101 ttgcataacc tgtggattct gagtttgaac tgccgaaaga acaatgtaaa gattgagtaa
    38161 actagtaagg cctagaaaaa tcaactccaa gccaccatgc cccagtccat aggccaaggc
    38221 gtctgccttt tccaaacttc tctttttctc aaaccatttg aagaaaacaa gacgagccgt
    38281 ttcctcaaaa aatgctgcca tggctaggcc atagataata tagataagcg gatgatcttg
    38341 caagagggca atactaccgt ctttttgagg gtgcaaaatc aagatatgca ccagtttttc
    38401 caaaatctgc gaagagacaa agaaagcgac tgcacccaag cccaagacag ctagattaat
    38461 ctggtatttc tttttggcaa accaaatgct tcctatcaga aaagctagca acagcaacat
    38521 ggtaataatg atatgaatgg tcattttctt ctcctattct gccttttcaa tatctttttt
    38581 catctcgtca acattgaact tagcaaacaa gtattgacgg tcttggactg ggaaacgttg
    38641 gtccaactgg tcaactgctc ccacctcgat aatgccttcc ttgatgacaa aatccatgac
    38701 atgtccaccg aaggtcaaat catctgatat gaagtgcaga tggtagcctg ccacactgac
    38761 cccatggaaa atctcaggcg tccagaaacc aacaatagtc cccgcaacat tgtcacgact
    38821 atattccggt tgatgggttg cgacatcagc aaacttggta tcgggtgttg acttaggaat
    38881 catacgcaca tgcatatgta aaaattcccc ccgaatcttg atagagcgga aaagattttc
    38941 cccatcataa taagactcaa ttcgttcttt caattccttg tctgtcatct caaagcgctg
    39001 gcggaaaatg acctctgcct gatgcggtac cactgcagcg taaggaataa gggcatctgg
    39061 tgacacttcc acaatttctg gctggtctcc tgaccctttg gcctgataag ccttgccatc
    39121 caagacaatc aattccccat caatggaatc caaggttccc aaaccaaggt caccatgttc
    39181 tagcaattct cctactgtca tagtaccacc ataaaggcca gccatcaagg ctccaagagt
    39241 attgtattga aataatttca ctggttcctg cacgttctta tccattcact ttcttgtctg
    39301 ttattctata aatcttactc ctaagtatac cacatttgcc cctagatgtg aacgagagaa
    39361 acgttctaga cattgccaag aaggaaaaaa aagggtacaa tgtaacaaaa tcaagggagg
    39421 tctggaatga agaaacaaag caagtacaaa gaggtcgttt cctatctgaa aaatggtatc
    39481 gagtctggac gatttccgac gggtagtcgc ctgccttcta tccgtcaact gagccttgac
    39541 tttcactgca gcaaggacac cattcaacga gccctgctgg aattacggca cgaacaatac
    39601 ctctatgcca agcctcagag tggctactat gtattagaac aagggcaaca tcaagaccta
    39661 gaaatcgagg ttaccgacga acatgccagt gcctatgacg atttccgact ctgtgtcaat
    39721 gaaaccttga ttggccgaga aaactacctc ttcaactact atgacaatca agaaggatta
    39781 gaagacctaa gacagtccat tcacaaactc ctctttgagc aagctctcta ctgcaaggct
    39841 aaccaactag tactgacttc tggaacccaa caagccttat ttatcctctc tcaaatatcc
    39901 tttcctagac aagccaagga aatcttggtg gaacagccaa cctaccatcg gatgaatcgc
    39961 ctcttgattg cacaggggct ggactatcaa acgattgaac gaggcattga tgggattgac
    40021 ttggaggagc tggaaggcca cttcaaaaca ggaaaaatta aatttttcta caccattccc
    40081 cgatttcact atcctctggg acattcctat tctgagcaag acaaacgatc tattcttaac
    40141 ttagctgcca agtatgatgt ctatatcgta gaggacgatt atctgggtga tttggactcc
    40201 aagaagggcc aaaccttcca ctatcttgat acagaggagc atgtcattta tatcaagtcc
    40261 ttctcgacca gcctttttcc tgcccttcgt attacagcac tcattcttcc aaatgctatc
    40321 aaagaagcat ttgtggccta caaaaatatc ctagactacg acagcaacct cattatgcaa
    40381 aaggccctgt cactctatat tgacagtcaa ttgtttgaaa aaaatcgttt ggctcgcttg
    40441 accaatcatg aatcttacca aaaacaaatc gaggaaagga taactaaaac accttgtccc
    40501 cttcctcatt atcccctaca cgatggttta ttgctagacc tgagacagta tcctaaaatc
    40561 gccagtctca aacacagtca actgggcttg gacttctttg aagaggccta tttgagcacc
    40621 tgtccttatc aatttgccaa ggtgtcccta gacaatctgg aaaatgtttt aaactattta
    40681 aaagcagaat tggaatgaca tccaactctg ctttttctta ttcttcaact tcagttagac
    40741 ttgctgcttt ttcaagatag ctttggtaag ttccttcatc cttaagtttt tggatgacct
    40801 tgtctaccac ttctttcaaa tcatcactat tttttctaag agcaacggca ttggcgtcgc
    40861 cgtccttcat cttcaagctg acagttgcga cagctaagcc agcgttttta gcagcataac
    40921 taagtgcaac aggctcatcc atatgaacag catctatttt tccagcctgc aattcattga
    40981 ctgcttcacc catattagtt agggaagtta attgagcttt tggcaattgt tccttgacca
    41041 ttgattctgg aacagtccct ttttgggctg caatattagc actttctagg ctagttaaat
    41101 ccttgtattt ttccacatca gccttacgaa ccaagaaact aatcttgttt tcatagtatg
    41161 ggattgaaaa atcaaagact tcttttctct cgtcagtagc actaattcct gcaactgcta
    41221 ggtcagcctt accagtttga agactggtca aaacattgtc aaaactcatg cttaagattt
    41281 ccaacttaac cccaagttca tcagcgatag cctgagccat gtcgatgtct gcaccgacta
    41341 cctggttctt tccatcaacc aatgattgaa attcaaaggg tgcatagtca ggactggttg
    41401 ccacaactaa tttccccttt tgcttaatgg cctcaacagc tgactgagaa ccattagaac
    41461 ctgactggca agctactaag aagaaacttg caagaaaatt acataaaaca aatatccatt
    41521 tttttgattt cataaataaa caacctttct gttaattttg tataattata acgatatcca
    41581 agttacttgt caagtgtttt ttaaattttt atctcaaaaa tattttttcg ttcaaaaaaa
    41641 ggagccatca gttgatttca agctcctttt tatacagaat taaactattt tatagttcga
    41701 caatcttacc tgtttcaaag tagacaaccc attcacagat atttttagca tagtcaccga
    41761 tacgctccaa gtaggaaata acttggaaat aatcacgacc cgtaacaatg gcttctggat
    41821 ttttcttaat ctcttcagtc gcaaggtcac ggatagtttc aaaatagtgg ttaatttgct
    41881 catccatgga ggccacccgg tatgcgtcgt caacagaacc attaagataa agatcaagtg
    41941 ctgcttccac aacgctttta acttcacgtc ccattttttt aatttcttcc tctacagctg
    42001 ggatgcgttc ttcccccttc atacggatgg ttgcctgggc aatggctaca gcgtgatccc
    42061 ccatacgctc cacatctgat acagccttaa ggacagtcaa gactgtacgc aaatcttgag
    42121 agactggttg ttggagtgcg atcatttcaa atgatttctt ttccagtttc acttcgtatt
    42181 catttacttc tgcatcatct tcgatgacct cttttgccag gtcacggtca tgcgtgacaa
    42241 aagcacgtac cgtacgattg atttgtgaga gcacttcttg tcccatagcg tagaactggt
    42301 tatgtaattt ctctaaatct tcttcaaatt gagatcgtaa catctttcat ctccttatcc
    42361 aaattttcct gtaatatagt cttccgtttc cttgtgttgg ggatcaagga acatctgctt
    42421 ggtatcatta aattcaatca aatctccatc taggaaaaat cctgtcttat cagagatacg
    42481 tgaagcttgc tgcatggaac gggttaccag aagcatggtg tacttgtctt ttagaccata
    42541 caaggtttcc tcaattttac cagctgaaat cggatccaaa gccgaagttg gctcatccaa
    42601 gaggatgatt ttaggactag ttgccaagac acgggccacg cagacacgct gctgttgacc
    42661 acctgacaat ccaatagctg aatcatatag acgatccttg acctcatccc agatagaggc
    42721 accttgcaag gctttttcta cggcttcatc cagaacctgc ttatccttaa ttccattgat
    42781 acgaagcccg tagacaacat tctcatagat agtcataggg aaaggattag gttgttggaa
    42841 aaccattccg atttccttac gtaattcaac cgtatctgta cgcggactgt agatgttgtg
    42901 accattgtac accacggatc cagttgtggt cacctctgga ttgagatctc ccatgcggtt
    42961 gagagacttg aggagggttg acttccctga tccagatgga ccaatcaagg ctgtaatttc
    43021 cttaggttgg aaagataggg aaacactatt caaagccttc tttttattat aatatacgga
    43081 caggtctgat acctgtaaaa tcgcatctgt catacggttt cctttctaac caaagtgacc
    43141 agatacatag tcattggtgg actgtagctt ggcattttgg aaaatagttg cagtcttgtc
    43201 atactcaatc aaatcaccca agtaaaagaa gcctgtatag tcacttgcac gagcagcctg
    43261 ctgcatatta tgcgttacaa tgatgatggt aaagtttttc ttgagctcaa acatggtctc
    43321 ttctagttgc atggtcgcaa tcggatccaa ggctgaggct ggctcatcca ttaagaggat
    43381 atctggctta acagagatgg cacgagcgat acagagacgt tgttgctgac cacctgataa
    43441 ggtcaaggct gacttgtgga gatcgtcttt aacctgatcc cagagggcag cctgacgaag
    43501 ggaggtttct acgatttcat ctaggacttg cttatcctta actccagcac gttcatgcgc
    43561 aaaggtaata ttacggtaaa ttgacttagc aaatggattg gggcgttgaa aaaccattcc
    43621 aatgtgttta cgcatttcat aaacgttgat ttctggacgg ttgacatcaa ttccacgata
    43681 gagaatctgc ccagttactt tagcaatatc aatagtatca ttcatgcgat tgagactgcg
    43741 taagtaggta gatttccccg atcccgacgg accaatcaaa gctgtaattt tatttctttc
    43801 aaattgcata tcaatcccct taatggattc atttttacca tagtaaacat ggacatcctt
    43861 agtagaaagg gctacttttt cttcaggaaa ggtaaggata tgcttctcat cccagttata
    43921 tgttgacatg gcttctcctt taggcagcgg ttaatttctt gtgtagatag cttccgaact
    43981 tacgagctcc aaagttaaaa atcaggataa agatcaggag cacagcggca gaacctgctg
    44041 atacaatggt tccatctgga atagtgcctt cactattgac tttccagata tggacagcca
    44101 aggtttctgc ttgacggaag atagagatgg ggctagtcac actgaggata ttccagttag
    44161 accagtcaag agctggcgcc gattgccctg ctgtatagat cagagctgca gcttcgccaa
    44221 agatacgacc agatgccaag acgacacccg ttacaatacc tggaagcgct tctggaataa
    44281 caacatgaac cactgtctcc cagcgagaaa tcccaagagc cagaccagcc tcacgttggg
    44341 tatggtgaac gtgtttcaaa ctatcctcta cattacgcgt catctgaggc aagttaaaga
    44401 ctgtcaaggc caaggcacct gaaatgattg aaaatccata ctcaaactgg actacaaaga
    44461 tcaagtaacc aaagagaccc accaccactg atggtaaaga ggacaagatt tcaatacaag
    44521 tccgcacaaa gttggtaaca ggaccttttt tagcatattc agccaagtaa atcccagctc
    44581 ccatagaaag aggtacagaa ataatcaagg taatgaccaa taggaaaaag gaattgtaaa
    44641 gctgaatgcc aatcccacca cctgcttgaa aagcagaaga ccttccagtc aagaaagacc
    44701 aagagatatg gggcaagccc cgaaccaaga tatagagaat caaggaagcc aagattgtca
    44761 caatgatgct agcaatcgta tagaggacag ctgttgcaag tttatctaat ttcttagcgc
    44821 gcataatttt tctttcctct ttctttcgta atcaatttaa tcacactgtt aaaaactaaa
    44881 ctcatcaaga gcagtaccaa ggccagtgac cagagaacat tattatttac agttcccatg
    44941 acagtgttcc caattcccat agttaatata gaagttaaag ttgcagctgg tgtggtcaag
    45001 gaagttggga taacagctga gtttccgaca accatctgga tagctaaagc ctcaccaaag
    45061 gcacgcgcca tcccaaagac cactgcagtg aaaataccag aacgggccgc cttcaagatc
    45121 acacgccaga tagtctgcca gcgagtggct cccatagcga aacttgcctc acgataataa
    45181 cgaggaaccg cacgcaagct atccgttgtc ataaaggtta cggtcggcaa aatcatgaca
    45241 aagaggacgg aaatccctga caaaatccca aaaccagtcc caccaaagac actgcgaaca
    45301 aagggaacga cgacttgcaa gccaataaat ccgtacacta ctgaaggaat cccaaccagg
    45361 agttcaatag ctggttgcaa aatcttcgcc ccttttggtg atacttcggt cataaaaact
    45421 gctgcaccaa tagcaaaggg tgttgcgata agggctgaga gaatggtaac gataaaggaa
    45481 cccaaaatca taggaagggc accaaattct ttactagaag gattccaagt tcctcccaaa
    45541 agaaagtcaa agatattcac accattgaca aagaaggtcg acaagccttt ttgcgctacg
    45601 aaaaccaaaa tcatggccac aaggatgact atcaaagaaa gacaggcaaa ggtcaaacct
    45661 tttcctaatt tctccagacg agaattcttt gatggaagca acattttctt agctaattct
    45721 tcttgattca ttattgtctc ccttccaaca ctgtcacagt tccggcagca tctttttcaa
    45781 ccttcatttc cttaatcgga atatacttca atcctttgac aatcccttct tgggtctcat
    45841 ccgagagaac aaaattgaga aattctgcag ctaactcatt gggctgcccc aatgtataca
    45901 tatgctcata agaccacaag ggccaattat tgctacttat attttctgga cttaagtcat
    45961 agccattcaa cttcatgctt ttgaccgaat catctatata ggtaagagat aaataagaga
    46021 tagctcctgg actttttgat acgattgatt ttaccgctcc atttgaatcc tgctcctgac
    46081 tttgcatggc agactgacct tccataatga cagtatcaaa ggtagcacga gagccagagc
    46141 cggctgcccg attgataaca gagatgggta agtccttacc accaacctct ttccaattgg
    46201 ttacctcacc tatgaagatt tgacgaagtt gctctgtcgt taggttatca acatcaacct
    46261 ccttattgac aatcagagcc aagccagcta ccgcgacctt gtggtcaaca agagcagaag
    46321 catcaattcc gtctttttcc tcagcaaata catctgagtt tcctatatca actgccccag
    46381 actgaacctg ggacaagcct gtaccagaac ctcccccttg gacattgacc gtttttccaa
    46441 catggatcgt gccaaattca tctgccgcta cttcaaccaa gggttgcaag gcagttgagc
    46501 caacagccgt tatggattct ccacgatcaa tccagctagc acagcctact aaacaagccg
    46561 tcagccaaaa agcgataaga gacagagcaa gcttttttct ttttttcact gtttttctcc
    46621 tcgaaaataa ttatgaatac tgtgaatttt ttaagtagtt ctttatgagt tgacgcatga
    46681 attcttacca aatttctgcg caattgatta tttatataat ataggctata ttactctttc
    46741 ctaacctcct tttttcatat gtggataaaa tctcttgtct atcccttccc ccattgtcac
    46801 ccattatagt catttcgtgt ctctttttcc cctttttaat gcaagggaaa ttactctcct
    46861 tagatgataa tccaaaagct agaaaggtat ctcaaatctc tctactctcc cagactagtt
    46921 tacaactaaa aggaaaagat tctattttat gagaaatcta gtttacaagc ggtaagaacg
    46981 ctaataacta aacttcttgt actctttgaa aatctcttca aagcagtgtt ttgagctatc
    47041 tatggctagc ttcctagttt gctctttgat tttcatcgag tagtaaaact acatgtgatg
    47101 gcaatcaaga tatcaagaat catcctacta aaaaaatcca tactttcact ataacataga
    47161 ataagatatt tgactagcat tttcatttga atctgaggcc ttttggaaaa taatttttca
    47221 aaacatttcc agtaaccttt gcaaagccca agccattgcc tttaaccaaa acttggtacc
    47281 aaccatttgg cagactttct gccagctgaa cggtttctcc agccgcatac ttgacaaact
    47341 cttcttggcc aatttcaacc gactgttcga cctgactcgg tttcaaggct aaaccaagag
    47401 cgaaactggg ctcaaagcgt ttcttcttaa aagtacccag atgcagtcca ttgcgagcaa
    47461 tcttgagctt ccctaaatct ggcaaaagtt ctggcaagag ataaagctgg tctccaaaaa
    47521 tctgcaagat acccggtaga ttgaccttca aatggttttg ggcaaattcc tgccacaagg
    47581 caacttgttc acggctgagg ttactcttac ttgccttaaa tttaggagct ggattgttac
    47641 ccttaaactg tagatgggca acaaactgac cctctccctt aaactgatga gggtacatcc
    47701 gagccgtttc tggcaggtca ataccagcta ccattccatt gatatgctct actggcaaca
    47761 agtcaaaatc atactcttcc agcaaccaat tgacaatctc ttcgttttcc tcgggtgccc
    47821 aggtacaggt cgaataaacc agacgaccac cttcagctaa catggtcact gcatcctcca
    47881 gaatttctct ttgcaagcta gcacattgac tcggataatc taagctccaa tagtccatag
    47941 catcaggttg cttacgaaac attccttcac cagagcaagg ggcatcaaga acgattaagt
    48001 caaaatagcc tttaaagacc ttgaccaagc ggtcggcaga ttcattggtc accacgacat
    48061 ttgtcgctcc aaaacgctcc atgttttcaa ccaaaatctt agcccgtttg cttgaaattt
    48121 cattggaaac aagtagcccc tcccctgcta gataggctgc cagttgagtt gatttgcccc
    48181 ccggtgcagc agccaagtcc aagaccttca taccaggact gggttgggct acttgagcca
    48241 ccatttgagc agcaggttct tgcgaataaa ctaaacctgt agcatgctca ggcgatttcc
    48301 ctgaaacctt cccatagtgg ccccaagggg tttgagtaat ggcatcagaa aaggaaagtt
    48361 gctcttcttt taagggattg acccgaaagg ccgaaaccgc ttcctcctca aaagaggcaa
    48421 gaaaatctct tgcctcatct cctagtattt ctttatattt ttcaacaaat ccttctggaa
    48481 atttcattta agttcttttc ctttcgtaaa tataggactg aatttcctcc tgcatctcaa
    48541 gaggcaccat catgaccggc tgtctggttt gaaaatcagg agcttcacca aaaagggtca
    48601 caacccgata gcccagactt tcccctaaaa tactagctgc ggcataatcc catggttgca
    48661 gataggtgag ataggtcaac aaacgccctg acaaaatctt ggcaaaacta atggccgcac
    48721 ttccatagac acgaacacca agaaccgctc ggctcaaatc agccagcccc cattcattgg
    48781 tttccagcat accactattc cctgcaatga gaaaatctcc aagtggttta gttttaaaag
    48841 aagctagggg cctatcattt agacaaactg gaaattcccc accaccgtgg taacaatccc
    48901 ctttgaccac atcataaatc agaccaaact gtccctgacc attttcaaaa taagccatca
    48961 taacagcaaa atcttcctgc tgggctacaa aattattggt accatcaatg ggatcaatga
    49021 cccaaacctt gccctcttga accgaggctc gcagacaacc ttcttcagca caaatcttat
    49081 cctcaggata acgggacaaa atctcaccaa ccaagagttc ctgaacttct ttgtccagtc
    49141 tggtcaccaa atctgttgga gaggacttgg tttcaacacg caagtcttcc tgcatatggt
    49201 caagaatgta ctgacctgct ttcttaacaa gctctttagc aaattcaaat ttacttttca
    49261 agagaaatct ttcctttccc tttttctttg gcagcctgaa ctgctcggta aagtgaatag
    49321 ccactaaccg tttcaaattc tcgtcccaaa cgtttctctt cgctcttgct tggcacgacc
    49381 gctttgaatc ccttatagga gtccagtaac tttttagcct ctactttgcc ttcataggca
    49441 gcttcaacat cattaaaaaa agaaagcact gaagcaagtt cttcagtgct ccacgacaaa
    49501 tctagtgggt aactatactg tttgttcatt aactaatacc agctctcatt cttgcttctt
    49561 ttagttcttg cttacgataa ctacgaggga gaaaagcacg aatctcatct tcattaaaac
    49621 cgatttgcat acgcttggca tcaataataa ttggacgacg caaaagacta ggatactgct
    49681 caatcaaatg aagcaattcc gataccgaaa tactctctac atcaatattc aatttttgaa
    49741 aaatttttga acgagttgaa atgatgtcat cagtaccatt ttcggtcaag gaaaggatgt
    49801 gttgcaattc ttttcttgtt aaaggactgg tcataatatt gtgttccaca aagggaacct
    49861 tatgtttttc taaccaggtc ttagccttac gacatgatgt acagctcggt gatagaaata
    49921 gtgtaatcat gcttttctct tcttatctat actttgctac ttctattata caaaaaaata
    49981 aggcgcttga ctagggattt ttagaaaaaa agcctatttt ttcaggaaaa ataggctgtt
    50041 tgcgaacgat tgacacaatt ggatttggtt aattcactct taacgatggt tttaaacgat
    50101 atatatattt atatatgtaa attaaaaaca tctttccttt cacttcctac gacttttcag
    50161 acacagatag ccaaagaagc tttcatagag ggcaaaaaag aggaggaagg catgaagaaa
    50221 gaaggtctct ggcaaaatca taataacagg atccttggct ggatcaaaaa gccaggtatc
    50281 atctcccaca aagagaattt gatggaaaag agtaaagaat tggtcaaaac caatcaaaac
    50341 tcccccaagt ccaatcatca caggtaagac tactagagcc aggagacttt ttcgataaag
    50401 agacaaaaag tcctttttca caatcctatt gacaaagaca tagaaacttg gcagtgtcac
    50461 tagagctact agctgaacca aatgaaagag attcttgacc actgcgaaat ggtgcaaacc
    50521 agctgctgac gaacgaaaat caggcatctg taagacctga ctaaaaggat tggtcagata
    50581 attcatcaag atatgaaaat tgtattgaat ggtttctggt tttagataga ctcgattcgt
    50641 taagtttagc cactgaatct ccataggata gaaaatccaa gccagataaa tggtcagaag
    50701 gattgagagg gagaggagaa agagcataga gccccaaaag gtcaatttag ttttcatcaa
    50761 aatcccactc cgcaaggcta gaaaccacat gtgtcggtgc gattggcagg ccagctactt
    50821 cttctgcctt ggtaaaacct gtcgtcacca agagcgttgg aatgccattg tcaatcccag
    50881 cccggatatc agtcaaataa ttgtccccaa ccatgattaa ctcttcacgt tccaaaccta
    50941 agtgctcaac tgccttgtcc ataatgatgg cattgggttt tccgatataa accggcttca
    51001 ctcgtgtcgc tacttcaagc agcgtaatca gtgagccagc acctggcaaa agaccacgtt
    51061 ccgtcgggat gttgaggtca ggattggttc cgataaaatg ggcacccttt tgaatagcaa
    51121 gagttgctgt ggcaaatttt tcatagtcga cttgccaatc cagaccaact accacgtagg
    51181 caggtttttc cttgtcttcc acataaccag ccgccttgat ggcttccttg agtcctgctt
    51241 ctccgacaac atagacggtc ttttcaagcc ccaaatcatt catatagtcg atggttgcca
    51301 aagtcgctgt gtagacagtc gataggggcg tatcgatatt aaaattctga gccaacatct
    51361 ccttaacact ctctggagtg cgggttgtat tgttggttac aaagagatag ggaatgtccc
    51421 gcttttgcaa ttcatgaaca aaagtctctc cagcagggat ttggtctttc cccttataaa
    51481 tggttccgtc taaatcaatt aaatagcctt tatatttcat ctatttctcc ctaagccttt
    51541 tttatttctt gccaagtaat gattgcttgg gcattgataa ccccatcact tgtaatttca
    51601 tgcttgcttt ccagtccagt ccgttcaaca gccgatgtaa tcaccccacc tggtcgaact
    51661 tccttgacat acttgaggtt gattttcttg ggaatatagt gggtcaaaaa atccgctccc
    51721 atgacctcaa aaatccagtc taagtattta ctgttattga catgaccatt catatccaag
    51781 tcgtaaaaac gaacatggta atccttgctg atcgactctt ccaaggactc atacttcggt
    51841 ccacggataa gttttttatc aaaatcagac tggtaaggag ccacaatctc aggttcaaca
    51901 gcatggactt ttcgactgtc gcggtccatg agaacaaagg tcgccatcat atggatgagc
    51961 tcctgccccg cttcattata aatagtaaag cgacggtagc aaaaaagtcg attgtagctc
    52021 aaggcttccg tttcgatggt aatttcttcc gcaaaacgag gcaaacgaac cacctcaata
    52081 tcatattcta cgataatcca gaccagatta tagtcttcca aaatggcctt atcactaact
    52141 cccagttcaa tcgactgcat ccctgaaact tgcagtgaca gcaaaattac atctggaagt
    52201 ttgatatgac cgttcatatc agccatatca aaaggaattt tcattttcat ttgataagtt
    52261 aagcccatga tcctactcca aaataaatcg ttccgctaca gtatctccca aaaagagacc
    52321 tctctttgtc atgcgaacgt ggtcaccctc aatctgcatg aggccttgtt gaaccaaatc
    52381 tctgacaatt tctccataaa gtccagcaaa agactgtcca aatttttcct caaatcgcgc
    52441 catggaaacc ccggatttct tgcggagtcc caagaacatt tcttcttcca tttgctcctt
    52501 ttgactcagg tgatcttctg taatacaagc attgccttcc tcaaccgcac tgagataatg
    52561 acgaatggga ccatgatttt tatagcgtac tccattgaca taaccagatg cccctgcacc
    52621 aataccatag tattcagcat tgtcccagta catgagattg tgacgacttt caaagccggg
    52681 tttggagaaa ttagaaatct cataatgctc aaaacccgct cgctccagct ctgcaatgat
    52741 gtactcaaac atctccgctt ctagttcctc cttaggcaga ggcaatttcc cacgtcgcat
    52801 ccgattcata aagaccgtat ggttttctaa aatcaaacta tacaaactca tgtggggaat
    52861 atccagtcca atggctttag ccacattttc ctttacttgc tccatggtct gaccaggcag
    52921 agcataaatc aaatcaatgg agatgttgtc aaaaccagcc agtttcaggc gatcgatatt
    52981 ttcataaata tccttctcca aatgactgcg cccaatcttt ttcaacatct tatcatcaaa
    53041 ggtctggaca cctagcgaaa cacgattgac agccgaattt ttcaaaacag ctatcttatc
    53101 cgcatccaaa tcgcctggat tggcttcaat ggtcaactct tctaagacag acaagtccaa
    53161 gtttttagtc aagccattca gtaaaacctc cagttgcgga gccgacaggg ctgtcggtgt
    53221 tccaccaccg atataaaggg ttgacaactt ttcaatatca taagaacgaa actcttccag
    53281 cagatgctct aaatagctgt cgactggctg atttttgatg aagacctttg aaaaatcaca
    53341 ataataacaa atctgggtac aaaatgggat gtgcacatag gctgacgttg gttttttctg
    53401 catagtaatt attataccac aaagactaga ttccagataa aaatcaccat ccccagatac
    53461 atagtccgtc cggagatggt gatggtttat tcttctgtta tatcaatcac aatctcttct
    53521 gagtcatcaa gagcttcggc tttttcttgc cattgctcct tgagattatt taattgattt
    53581 tttgatgctt ctgtcgcttg aaaagcatag gatttagctt gagcaagtat actgtccaca
    53641 gtgatttcac ctgactcaac ctgttctttt gttttcagaa caaaatctgt agcctgctcc
    53701 ttaacttctg tcagtttttc acagacttgc tccttggcat actccggatc ttctctcaaa
    53761 tcatctagaa aatcttgagc ctgactgcaa acttgtttgc ccttatcact tgttaaaaac
    53821 aaggcaagag ctgcacctga aacggttcct aaaaggattg aggataattt acccataagg
    53881 attctccttt tttatttttt gaaaaattta cttgcaagac gaagagctga cagacttgca
    53941 ccagtcttga gtgtttttga accagctgat gaagctttct tgctcaagac acgcgcatgg
    54001 tcattgaggt ctgaaacaga tagagataaa tctgcaacag cactgaagag tggatcaatc
    54061 gtagccacct tgacattgat atcatctgcc aagacattga ccttagccaa caactcattg
    54121 gtgtgatgca aggtcacatc cacatctgaa gtcaaggttt taatcgtctt ttctgtttca
    54181 tcgatgacac gaccaagctt ttgtacagta atgatcagat agaccaaaaa gacaatcaaa
    54241 gctagggcaa caagaatata tgcaacttct aacatttagt tttcctcctc tgtaatatag
    54301 taaggggcct tctttcgatt ttgataaata acgatcatta taccgagacc gataaggaca
    54361 actgacagcc attgggacac tcgaaggccg aagaacatga gactatctgt tcgcatacct
    54421 tcgatgacca tacgaccgaa accataccaa atcaagtaaa aggccgtgat atgacctcgt
    54481 ctgagactct tccatttccg tctaaaaatc agaatcaagg caaagccaag cagattccat
    54541 agagactcat aaaggaaagt cggttgacgg tagctcccct caatatacat ctggtcacgg
    54601 ataaagccag gtagataatc cagattatcc actgttgcac cataagcttc ttggttaaag
    54661 aaattacccc aacgccccaa actttgagca atcataacgc taggcgccgc aatatctaga
    54721 aaatcccaag tattgatgag tttacggtca gcaaagatat agagcacaag agccccagtt
    54781 atcaaaccac cgtaaatggc caaaccacca ttccaaatgg caaaaatctc tcctaaattc
    54841 tgactatagt aatcaaatcg gaaaataaca tagtagagac gagctcctaa aatagccaag
    54901 ggaaaggcta ctaagataaa atctaaaata tcgtctggta tgatcttctt tctaggtgct
    54961 tctttcatgg tcaaataaac cgcaagaatc aagcctgtca caatacataa ggcataccaa
    55021 cgaatggcta ggggtcctag ttgaatagca attggatcaa gcattttgca cctcatttcg
    55081 agcgatgaga cttgtcagtc gttcgtcgaa caaacgggtc gcatcaaagc ccatttcctt
    55141 ggcacgataa ttcatggcag ctgcctcaat cacaacagag atattacgac ctgttttaac
    55201 tggaatacga atacgaggaa tggctacgcc agaaacttca agttcctctg cattgtttcc
    55261 aagacgatca aaggtcttat gcgtatcgta attttccaaa tagacagcaa gctgaacctg
    55321 tgaagaatcc ttgacagcac tcgcaccgta gagactcata acatcgataa taccaacccc
    55381 acgaatttca atcaagtgtt tcaaaatttc agctggttca ccccagagag taatctcatc
    55441 cttggcaaag atatcgacac ggtcatctgc taccaaacgg tgaccacgtt tgacaagctc
    55501 aagacctgtc tcgctcttac caattccact atctccctga atcaagacgc ccatcccata
    55561 aatatccatc aagacaccgt gcacactggt acgttctgcc aaacgagaat ccagatagct
    55621 agataactct ccagataaac gactggtagc tgcacggctg gttaaaatag caatcttaca
    55681 ttctctagca gcctttaaca tctcctctgg aaccaccaaa ccacgggcaa caatgactgc
    55741 tggtgtctca gatagaaaca tttttttcaa aacttcataa cggctgttgg aaggcatgct
    55801 gatcagataa gaccactcct tcatccccaa aagttgaatc cgctctggtg tgtagtagtc
    55861 aaaatagcct gtcatttcaa gaccaggtcg cgtaatatcc gctgtattga tttccttttc
    55921 aagcaactct ggttcaccat agacaatatc tagtctaagc ttttcaatca cttcttttac
    55981 taaaaccgac atcatttcct ccttcaaatg agttcttctc tctattatat caaattgtag
    56041 gaggaagttt cagatttttg caggctttgg agtatttatt taaaagaaaa aggactagat
    56101 ttctctagcc tttcattcca attagaattt tttacgttta cgagctactt ctgatttacg
    56161 tttacgtttt acagaaggtt tttcatagaa ttcacgtttg cgtgtttctt gaagagtacc
    56221 agctttagta accgcacgtt tgaaacggcg aagtgcgtcg tcaagagatt cattcttacg
    56281 tactactgtt ttagacattt ttttcactcc cttcaagttc gatatctatt tcattctaca
    56341 cgtaaaagga ataattgtca agcaaaaatg ctgtttaatt ttgatttttt cttccattta
    56401 tacaagagtt gaaagcgttc aatagaacat tgctttttta tttttcgagt aagctaagcg
    56461 cttcagcatc tgcgatgatg gttacatcag ggtgattttg gaggctactt gcaggtaggt
    56521 tctcagtcac tgggccagat actgttccgg caatggcttc tgctttcgac tcaccgtaag
    56581 caaaaagaat aatagacttg gcatccaaaa tgtttttaat ccccattgaa atagcttggg
    56641 ttgggacgtc ttcaatcttg gcaaagaagc gtgcattggc ttcgatagta gactggtcaa
    56701 gttctactag atgcgtttga ctgtcaaatg gagtaccagg ctcattaaag ccgatatgcc
    56761 cattgcgacc gattcccaag atttggaggt caactggatg gtcagccaaa atttggttgt
    56821 agcgttcaac ttcagcttca gcattgtcct taacaccacg aggcaagaaa ctttctttaa
    56881 atggtttttg gttgaacaag ttttcttgca tgaagtaacg ataagactgt ggattgtccc
    56941 catcaaggcc cacatactca tcaaggttga cactggttag atttgaaaaa tcaaggtcac
    57001 tctcaacaat ttccttgtaa aattcaagtg ggctacttcc tgtcgcaagt cctagagttt
    57061 gagctccatt agccaatttt tccttcaaaa tctcaaaagc aacttttcca ccttgaactt
    57121 ggttttcaac tttaataact ttcatctttt catcctccat ttctgtctat atttattata
    57181 tggtatagac caatttttgt caagtgaaaa cgatttaatt tctaaaaaaa gagcgtccaa
    57241 acttgaaacg tgttataatg gataggatta gaacttagaa agaatgaaca gatatatgaa
    57301 tacagctgat tttgatttcc acttgccaga ggaattgatt gcccaaacgc cccttgaaaa
    57361 acgtgatgcc tccaaactcc tcatcgtcaa ccgtgagaca ggagaaatgc aagataaaca
    57421 cttccactct attattaata tgctggaacc tggtgatgcc cttgtcatga acgacacccg
    57481 agttctccct gcccgcctct atggtcaaaa agtggagaca ggaggtcatg tggaacttct
    57541 cctccttaag aacactagtg gagacgagtg ggaagttctg gctaaacctg ccaaacgcct
    57601 caaggtcggt actcgtatca gctttggtga tggccgcctc agcgctgtcg ttacagaaga
    57661 attgacccac gggggacgca ttgtccgctt tgaataccaa ggaattttcc tagaagtctt
    57721 ggaaagtctg ggagaaatgc ctctgccacc ttatatccac gaaaaattag atgaccgtga
    57781 acgttatcaa accgtctacg ccaaggaaag cggctctgct gcagcaccga ctgctggtct
    57841 tcacttcacc aaagaactgc tggcagaaat ccaagctaag ggtgttcatc tagtctatct
    57901 gactctccat gtcggactcg gaacctttag acctgtttct gtggataatc tggacgaaca
    57961 cgaaatgcat tcagagttct atcaactttc tgaggaagct gctgccaccc ttcgctctgt
    58021 caaagaaaat ggtggtcgcg tcatcgctgt cggaaccact tctatccgca ccttggaaac
    58081 tattggttcc aagtttgatg ggcaaatcca agcagattct ggttggacca atatctttat
    58141 caaacctggg tatgagtgga aggtcgtgga tgccttctca accaacttcc atctgccaaa
    58201 atcaactctg gtcatgttgg tttctgcctt tgcaggccgt gaattagtct tagatgccta
    58261 ccaccatgcc atccaagaac actaccgctt cttcagtttt ggtgactcca tgtttattta
    58321 ttgagaaaga atttctctaa atcttctaat accaataaat cgctaagata ttatttcaaa
    58381 gaacatctac aattgaaact ctagctagct gtagaagacg cctagtacat tgaaattaaa
    58441 atgcttcccc ctagcttcga aaatattgcc atagattgcg ttgactctcc aaattgattc
    58501 atctatattt tatttcagct tcctatattt tcttcgctgt ttgtaaatca aaatgcaaga
    58561 cacatgagta gcaccatatt tgttactctt atctgtcctc tcaagagact attatgagtt
    58621 atttcagaat cattcactac tttgaccctg actctcctta gtctcaaaat caaagactta
    58681 tactcttcaa aaatctcttc aaactgcgtc aacgtcacct tggattatat atgtgactga
    58741 cttcgtcagt tctatctaca acctcaaagc agtactttga gcaacctgcg actagttttc
    58801 tagtttgctc tttgattttc attgagtatt aaacaaaaag tgaacaaatc tgaattctaa
    58861 tgtacagaag actaggcttg ttcacttttt tatagtcgct ataagatgac cttatctata
    58921 gctttttata tataattata tataattata tattcagaca tactattatc aattttgtcg
    58981 cagggaggaa tctgttaacg cacccattca ccattatcat tgactctata gccatctata
    59041 cttgtattga ccgctaactc acccgatgca tttacataat accatttacc accaacttgg
    59101 aaccattgat tgactttcat agaaccgttg ctgttgaggt agtaccatga accattaact
    59161 tgtacccaac ctgttgccat ggaaccatca gtattataaa aataccacat accattttct
    59221 tgtttccagt ctgttgttgg agcaactgct ttagctggtt ctactgctac atctgttcct
    59281 tggttagatg taacagatac aggatacgaa ggaatagatg attgctcagg aacaacaact
    59341 ttttcaggtt ctctcgtccc tctccttata cgtcttttta ccatctcttt agtaatttga
    59401 cgagaagtag tttcttcaat tgttccatca cgttcatcta cagtatagat tgtagtaaga
    59461 gtaatttacc aatttctcct acttcttcta cttcttgact tttatcaaga gttgggtcat
    59521 cgagatattc tgtttcgatt ggaatttctt ggacaagaac ttggggcttg gttccttttt
    59581 taacaactct tgtttgagag tcttcttttt gacttaaagt actctcagtt acttgtccac
    59641 tctttccatc tacatcataa gttatcgttg taactgtttt cccattcttt cctagagtaa
    59701 tctcttgctc ctgtcctgca gaaaggtcat tgtctgcttc atatttagta gcacatggaa
    59761 caagaacttc ttcaaccttg cttttagctg gaactttgat aactgtatcc gtggcttgtt
    59821 ttctatcaac agtaacctgt tcggtaacat gaccagtctc tggattaaca tcgtaggtcc
    59881 ttgtcgtagt tacatagcca tcctctccat caattgtaac aggattttca ctacggtctt
    59941 ttgtttcatc tttttcataa cgaattcgcg tacttgaaat tttcttggtt actaccttag
    60001 gtttagtcgc tacttttaca ataatacccc cattgtcagc gtcatcatac tctattccct
    60061 cttctttatc tctagtatca tctctgacat attgaatccc atcagcagca tgaacaaaac
    60121 ttgtattcag attcctccta aaaataaagt tagcccgatt accgcagaac caaaaatctt
    60181 tccgagttta cgtaatgcat agcgcttatt agtattagat tttgccatta catcctactt
    60241 ctagtatagc atcttttcta tcaaacgtta aacaatatac tttatatata aaatagactt
    60301 agaatgatat attgattatt gaactaacac tttaactata tcgtaatcaa tctcatatat
    60361 aaaggattgc agacatctta tctaaataca tgctaatata tttagataca aacattccaa
    60421 cttgataatt ttcactcatc tttcatcatt ccttatacaa ctatgcagta taaatagaat
    60481 agttttctca tcagaatgag actattttaa tattagataa tttgatagaa aaaacatgaa
    60541 taaaattggt tgaatttaat tccctaactc gatagaggat tctattttaa atttaacaac
    60601 agctaggatt acactataaa aagtacatta ccacctgttc ggctggagaa tctagtcgat
    60661 tagctccctc ttagttacaa gcttaaagcg attttttaac taatactaaa ccagattaaa
    60721 gaaggaacta gaacatctgt cttgtactaa tcaatatgct attttaaagt ttcaaataaa
    60781 cttggaatgc taattattat atttacaata aatagttgac ttcgatagaa acagaaaata
    60841 gaattcaaca ttcttcccta cttataccat aataaataag atccgcaaga tagccttttc
    60901 tctctacacc attaacaatg gtttgtagat aggacattcc agccttttcc atgacacgac
    60961 ctgaagctgg gttgagactg gcataacgtg ctctgacctt ttgaaaacct gcttgagtaa
    61021 aacaaaagtc caagatagct ttcaaagtct ctgtcatcat accatttccc cagtaagcct
    61081 tgcctaacac atagccaatt tcacagctta aatcagcctc gtctatctta acgatgctga
    61141 tatctcctat cacttgctct gggttttctt ttagacaaat ggcccattta taatagttga
    61201 gattagtata ggaagcaacc caattgcgaa tcgagtttcg agtgatttcg atatcaggat
    61261 ggggatccca ggtaacatag gtcagattct cagcagatga agcccaattt tgaaacatgg
    61321 cttctgcatc actctccaca aatcttctta aaatcaaacg ttctgtctgt aatatttgcg
    61381 taccgataga tttcatgatg ctacctcact tccttatttc tatgctcgta gtaaaaaggc
    61441 tcaactcagt aacagctaga aaacgagttt gtcttctaat ttcttgacgc agtcgctgcc
    61501 tggtttgaaa tgcgctctag caagcttttt caaacctagt catcgttgca ggggtaagac
    61561 gatgaaatcg aactcttcga gttaccgaat ctgcctcatt ttcttatttc taaactcggg
    61621 gttcaagatc ccccagacct tctctcactt tcttatttca agatgagagg ctgaaaacct
    61681 ccagtggagg tttttcttgc tttttaattt cagggcaaga agctaaaaag gtccccggac
    61741 cttcttcgct ttctcatttc taggctcagg gtaaaaacct ccaatggagg tttttactcc
    61801 caaaagtcat caaatacagt gatgggtaag tggcgtttgt gttggccttt gtgccaccag
    61861 ttttcaatgg tcgcttgagc ttctgggctg attgttttgc cttctaggta gtcgtcaatc
    61921 tctgcgtagg tgactccaag tgcgacttcg tcagctaggc ctggtttatc ttcttctagg
    61981 tctgccgttg ggattttttc ataaagggct ggctctgcgc caagtttctg caagagctgt
    62041 tttccttggc gtttattgag gcggtaaaga gggagaatat ccgcaccgcc gtcaccaaac
    62101 ttggtaaaga aacctgtgat attttccgcg gcgtggtctg ttccaatgac cgctccgcta
    62161 tgggaaccag caagggcata ctgagcaatc atacggcaac gtgccttgat attccccttg
    62221 ttgaagtctg aaacaggact acctgtcgct tcaactgcag ctgtcatggc atcagctgat
    62281 tccttgatat tcacaaccaa gctgacatct ggctggatga aggctagggc tttttgagca
    62341 tctgcttcat cagcttgcac tccgtatggc aggcggacag cgataaattt gtagctgtcg
    62401 tctcccgttt cagctcgcag ttcttccata gctaattgcg ccaaacgccc tgccaaggtt
    62461 gagtcttgtc ccccagaaat ccctagtaca aaggttttta ggaagggatg ttttttcaga
    62521 tatcttttta agaaatcaat agaacgacgg atttcttcct gggcatcaat cactggtttg
    62581 acacccagct cttggataat cgtttcttgc aaactcattc ttcttctcct tcaccaaggg
    62641 cttccttgcg catcttatca atcaagtcca tcttatcttg ccatacatca cgcgccaaat
    62701 ccactggata gtgctgcgga ttgagcacac gcttatactc atcccacaac ttgtcaaatt
    62761 ccttacgggc ataatcctga atgtcagtca aactaggcaa gttgtaaact aatattcctt
    62821 ctttgaagat atccaccaag agaggaacgg catcaaaatt acgaaccgtc ttcttgatgt
    62881 atgtataggt cggatggaac atcttgattt ctgtcatgtc gctaatatcc acaccatcat
    62941 aagtgatata gtcgccttct gacttgcctt tttcacgact ggtaatgcgc cacacctgct
    63001 tcttacctgg cgtagagact ttttccgcat tattagacag cttaatcgta ttgcgcatct
    63061 gaccagtttc atcttcgatt gcaacaatct tgtaaactgc accaagagct ggctggtcat
    63121 aagctgtaat cagcttggta cccacgcccc agacatcaat cttggccttt tgcatcttga
    63181 gattgaggat ggtattttca tctagatcat tagaagcata aatcttagcc tctgtaaatc
    63241 cagcctcatc cagttgctga cggactttct tagaaatgta ggcaatatcc ccagagtcaa
    63301 tccgcacacc cataaagtta atctgatcac ccagctcacg cgccacctga atggcagctg
    63361 gtacaccgat gcgaagggtg tcataggtat ccacaagaaa gacacaattt ttgtgggtcg
    63421 cagcgtaagc cttgaaagct tcatagtcat tgccataaac ctgtaccaag gcatgggcat
    63481 gggttcccaa aacaggaatg tcaaagagct tacccgcacg cacgttgctg gttccattgg
    63541 cgccaccaat cacagctgcg cgtgttcccc agatggccgc atccatttct tgagcccgac
    63601 gtgtcccaaa ctccatcaag ggttcatctt cgataaccga acgaatacga gctgccttcg
    63661 tcgccaccaa ggtctggtag ttgacgatgt tcaaaagagc cgtttcgacc aactgacatt
    63721 gggctagagg tccttccacc tgcacaatcg gttcattagc aaaaaccaaa tccccttctt
    63781 gggcagaacg aacggtcaac tccaacttga aattgcgaag gtaatccaag aacgccccat
    63841 gataaccaag cgactccaaa taggctatat cactatctga aaaacgcaag tcttcaagat
    63901 agttcacaat tctttccaaa cctgcaaaaa ccgcatagcc gttcttaaaa ggctgttggc
    63961 ggaaatacac ctcaaagacc gccttcttat tgtgaatccc ttggtcaaag taaacctgca
    64021 tcatgttgat ctggtacaag tccgtgtgca atgtcaaact atcatctgga tacatacttt
    64081 tcctacttcc ttagctagaa acccatgaaa attttcaaga actttcatgt attccaataa
    64141 attagtacta ttatatcaca ttttagctgg attgagaaaa gagtaacaag ctattctcca
    64201 ctctccaatt catccatatc ttgttcaaat tttttctgag cccattcgcc atagctctta
    64261 agaccaagat tgccaataaa gacccacgga aggtaaatga cataagtaat gacccaagca
    64321 gacaggtatt taaaattcaa aggattgtgc tgataaattt ctatgttgaa ttgataattc
    64381 tgcaacatca aaagagccgt aatagccaag gttaggaaaa aacaacccaa aatcgtaaaa
    64441 tgaaaacgac tatagtaggt cactcccaga taacgggcac ggttaaaaaa gtaaaatgtc
    64501 cctatgatga taacgattag cagcatatta gaattaaaaa ggcttggtgc taatactgaa
    64561 atgatataag ataggagcga caaagcgatg cagatataga aactttcaga gcccgcttta
    64621 ttgatcagtt gttcttctct ttcgtctagt aattgataat aataaaatct atttttcatc
    64681 ttcttcctcc caaaatagtt ggtctagggt tttccctaaa catctgcaaa tagactggca
    64741 gagcgagaga ctgggattgt attttcccgc ctctatcaaa ccaatagtct ggcgtgtcac
    64801 cccgacagcc tctgccagtt gaccttgtgt taaatcacgc tctacccgag ctaattttaa
    64861 ttttaaattt ttagccacct tcgtcctcct tatagtttta atactcatct actctttaaa
    64921 aatccaaact aacacaagct gtcagctatt tattataacc ccattaattt gcactccagt
    64981 attatcttca gccgaaaatc agtattttag gttgtttgaa ataaacttcc tagtttactc
    65041 ttttattttt atttttattt agcattagct ttagtaggat cttttaaacg agtttttatt
    65101 gcttatattt cttgtttagt ttagttggtt tcatatcact attatataat gcttttggaa
    65161 atgagcctag tataagtcaa aaacgtgttg aatagtgaaa gcaggagcat accaatatga
    65221 ctgatttttt actgtatttt aggtatgcaa aataatacta aatgaaacta aaatgaatac
    65281 ttcttgcttt tcttgagagt gaaaaagtac aataaaatga ttgtagtgat tgccacaaga
    65341 tactgactaa tagacatcgt atttgaagcc acaaatacag gtaaagaata aaaaggaaga
    65401 agttcaattg ctttgataaa caaatcatta ctagtattca tcatcgtatt taatatatta
    65461 gggataaaga gtagtaaagc tactaaaata ccaagccact tttcaatttg tataaataga
    65521 aaatgtaaga taatagaaaa taaaacagga ctaacaaaat tgtattgact acaatagcta
    65581 ctataaaatc taatcctaaa tcacctggaa tacccaattt acttactatg actagtaaca
    65641 caatgccatt caaagcataa ataatggaag ctgagatggc atatagaaaa ttagacaaga
    65701 cgtaaatcat ccgattcttc tgttgattat aaaacaaact taccgtattg tgggaaaaat
    65761 ctctactaat gactcgatta gcatgtataa cagccattaa cataccgagc atagcataaa
    65821 agtttgaaat atgcttaata ccaagcgatg tcccttaagt ctttagaata aagaatgtaa
    65881 gcaatatcgg cggtataaac gagataagca aactgagata tattacgcct gatgaatata
    65941 aatttcttat attttcctta agaaaattca atttatttaa tttcatgatt ataaccttcc
    66001 tttattttga acgatttagg taaatatctt taagcgtctc ttttttagtt tcaaaatcaa
    66061 ctactttaat agagttttcg ttaaaaaatt taaaaagctc actactttga atattcccag
    66121 acatagtaat tctcaatccc tcttcctgaa caatatcccc aaattcttgt ttggtaatga
    66181 aaatgtctct atctgtagct gatgaaaaag ctatctcaaa caagaaatta tgactatctt
    66241 ttcctacttt ttgaaatgtc aaaagcccgt tctccaagaa aagaactctc tcacaaattt
    66301 cttcaatgtc ttctaattta tgactcgata ttaaaattcc cacgttttca tttaaagcta
    66361 atttttttag aaccgctaaa actatttgtg atgattcaat atctaaacca ttagtcggtt
    66421 catctaaaat caatatatca ggttccgtaa cgagagttag aagcaaagct aatttttgtt
    66481 ttgtacccaa agaataggtc tttacttttt tattaataga ctgagtcaaa tctaactctt
    66541 ggatcaaact tctaaatctt tcttgattgt agtcaacacc atataaattt gacaaatatt
    66601 ttaaattctc taaacctgtt ttagataaaa ataattttgg ttcttcgatt aaatacccaa
    66661 cattatcact gcttataata ttacctgaag tcggttgatt attttgaaca agaattttca
    66721 tcaacgtact cttaccaact ccatttctcc ctactagacc aacaatttca cccttgttaa
    66781 gtgcaaaatt tatatctttg agaatgattg aatgaccata atgcttactt acatttttat
    66841 tcctacatta atattcatgg tttactcttt gattcttatt gagtttaaaa agttgcgcct
    66901 ctttttaaca atattatatc atatatctaa cttgatgcaa tatataaatg tcattttgta
    66961 aaattttatt aacaaaaaac tctctacaac aaaataatag agagttttct gcttattaat
    67021 ttttttcaaa atatctaaga catcgcttct ttgtttaatt tgataggctt tgatacctaa
    67081 gctccgactt tatcacttaa aaaataaaaa agacagctaa tctcttgcgc atcaagggat
    67141 ttcgccattc tttaatctcg tttaagtgtt gtatatggag ctttgcataa ttttttaaaa
    67201 ctaaacaact acattaagca cgaactgtga cgctggttcc atcttcctta taaagattga
    67261 taagcccctc tttaagagct cgaaccatgt ctcctgattg aacgggttgt gggac
//
LOCUS       DAVBCA010000003        64160 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.003, whole genome shotgun sequence.
ACCESSION   DAVBCA010000003 DAVBCA010000000
VERSION     DAVBCA010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 64160)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 64160)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..64160
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.003"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(136..483)
                     /locus_tag="VQU19_000149"
     CDS             complement(136..483)
                     /locus_tag="VQU19_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET2479478.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(594..2369)
                     /gene="spxB"
                     /locus_tag="VQU19_000150"
     CDS             complement(594..2369)
                     /gene="spxB"
                     /locus_tag="VQU19_000150"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HET2479479.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAISKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            complement(2576..4819)
                     /locus_tag="VQU19_000151"
     CDS             complement(2576..4819)
                     /locus_tag="VQU19_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HET2479480.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYIVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLTGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDIIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQSLHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLAISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            complement(4829..5200)
                     /locus_tag="VQU19_000152"
     CDS             complement(4829..5200)
                     /locus_tag="VQU19_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HET2479481.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QVGEFGFACGMNMMHGKMIVE"
     gene            complement(5211..5606)
                     /locus_tag="VQU19_000153"
     CDS             complement(5211..5606)
                     /locus_tag="VQU19_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HET2479482.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTIQTLL
                     ARLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     regulatory      5790..5888
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            5972..6763
                     /gene="thiD"
                     /locus_tag="VQU19_000154"
     CDS             5972..6763
                     /gene="thiD"
                     /locus_tag="VQU19_000154"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HET2479483.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEGMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     gene            complement(6972..7604)
                     /locus_tag="VQU19_000155"
     CDS             complement(6972..7604)
                     /locus_tag="VQU19_000155"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HET2479484.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARKVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPV
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(7597..8400)
                     /locus_tag="VQU19_000156"
     CDS             complement(7597..8400)
                     /locus_tag="VQU19_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HET2479485.1"
                     /translation="MQALTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRMAASYANQSSLPMVVDAVGVTTSSIRKS
                     LVKDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MSFLVTGPKDLIVSENQVAVLENGCTELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            complement(8400..8924)
                     /gene="thiW"
                     /locus_tag="VQU19_000157"
     CDS             complement(8400..8924)
                     /gene="thiW"
                     /locus_tag="VQU19_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HET2479486.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFAERID"
     gene            complement(8929..9621)
                     /gene="tenA"
                     /locus_tag="VQU19_000158"
     CDS             complement(8929..9621)
                     /gene="tenA"
                     /locus_tag="VQU19_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HET2479487.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEINDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            complement(9632..10282)
                     /locus_tag="VQU19_000159"
     CDS             complement(9632..10282)
                     /locus_tag="VQU19_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HET2479488.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAIFPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQKLHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAYGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            complement(10284..11669)
                     /locus_tag="VQU19_000160"
     CDS             complement(10284..11669)
                     /locus_tag="VQU19_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2479489.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQMI
                     AQVSSLPYSGQVLIDGSEVSQLSIVERVQTVGILLQNPNHQFTMESLFEELVFTMENI
                     GYHLQEIDSKIAEVVQQCRCKDILHRLIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELVYDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTQVASKEVASSPELFHMNRVTGELGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGSITWKGSVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            complement(11670..12230)
                     /locus_tag="VQU19_000161"
     CDS             complement(11670..12230)
                     /locus_tag="VQU19_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET2479490.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGFVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     regulatory      complement(12492..12580)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(12789..13418)
                     /locus_tag="VQU19_000162"
     CDS             complement(12789..13418)
                     /locus_tag="VQU19_000162"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HET2479491.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIRNEEEFQQSKVEYVDYVGVGPVFGTQSKDDAGGTIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNMDGVSIISAISYAKNIEKTVREMSEQ"
     gene            complement(13420..14202)
                     /gene="thiM"
                     /locus_tag="VQU19_000163"
     CDS             complement(13420..14202)
                     /gene="thiM"
                     /locus_tag="VQU19_000163"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HET2479492.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVMIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKEFKRVK"
     gene            complement(14445..15113)
                     /locus_tag="VQU19_000164"
     CDS             complement(14445..15113)
                     /locus_tag="VQU19_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HET2479493.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVDKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     regulatory      complement(15328..15416)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(15670..16806)
                     /gene="lctO"
                     /locus_tag="VQU19_000165"
     CDS             complement(15670..16806)
                     /gene="lctO"
                     /locus_tag="VQU19_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HET2479494.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     gene            complement(17431..18921)
                     /gene="lysS"
                     /locus_tag="VQU19_000166"
     CDS             complement(17431..18921)
                     /gene="lysS"
                     /locus_tag="VQU19_000166"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HET2479495.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLITKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKTIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            complement(19049..19195)
                     /locus_tag="VQU19_000167"
     CDS             complement(19049..19195)
                     /locus_tag="VQU19_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HET2479496.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAGDTF
                     TSFQ"
     gene            19421..20089
                     /locus_tag="VQU19_000168"
     CDS             19421..20089
                     /locus_tag="VQU19_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2479497.1"
                     /translation="MVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHYRILV
                     LAQVATAYIELSRNTPLLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGGSYMAESFR
                     SGLEAISQTQQEIGLAIGLTPLQVFYYVVLPQATAVALPSFSANVIFLIKETSVFSAV
                     ALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRLRHAGFGNPST
                     LSRK"
     gene            20049..20726
                     /locus_tag="VQU19_000169"
     CDS             20049..20726
                     /locus_tag="VQU19_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2479498.1"
                     /translation="MQDSGIQVLFQGNNLLRILQGLGVTIEISILSVLLSMMFGTVMG
                     IIMTSHSRIIRFLTRLYLDFTRIMPQLVLLFIVYFGLARNFNINISGETSAIIVFTLW
                     GAAEMGDLVRGAITSLPKHQFESGQALGLTNVQLYYHIIIPQVLRRLLPQAINLVTRM
                     IKTTSLVVLIGVVEVTKVGQQIIDSNRLTIPTASFWIYGTILVLYFAVCYPISKLSTH
                     LEKHWRN"
     gene            20727..21484
                     /locus_tag="VQU19_000170"
                     /pseudo
     CDS             20727..21484
                     /locus_tag="VQU19_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            21496..22357
                     /locus_tag="VQU19_000171"
                     /pseudo
     CDS             21496..22357
                     /locus_tag="VQU19_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765255.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
     gene            complement(22437..23084)
                     /locus_tag="VQU19_000172"
     CDS             complement(22437..23084)
                     /locus_tag="VQU19_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2479499.1"
                     /translation="MNEIIILKNIELKLKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(23081..23779)
                     /locus_tag="VQU19_000173"
     CDS             complement(23081..23779)
                     /locus_tag="VQU19_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2479500.1"
                     /translation="MGKLSSHMWRLNKIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLVLFCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDVGGDLFLQLLFLVFLFQ
                     SIFYFTRQKRRFIE"
     gene            complement(23789..24541)
                     /locus_tag="VQU19_000174"
     CDS             complement(23789..24541)
                     /locus_tag="VQU19_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2479501.1"
                     /translation="MKQFVQFYKKDFLSVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLNNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            complement(24541..25305)
                     /locus_tag="VQU19_000175"
     CDS             complement(24541..25305)
                     /locus_tag="VQU19_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2479502.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKKYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQLLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKIGAIFIPVAYMMVGGIFWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            complement(25984..26616)
                     /locus_tag="VQU19_000176"
     CDS             complement(25984..26616)
                     /locus_tag="VQU19_000176"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HET2479503.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYRELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            complement(26650..27351)
                     /gene="pyrF"
                     /locus_tag="VQU19_000177"
     CDS             complement(26650..27351)
                     /gene="pyrF"
                     /locus_tag="VQU19_000177"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HET2479504.1"
                     /translation="MREHRPIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKVLSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQNWN"
     gene            27672..27764
                     /locus_tag="VQU19_000178"
                     /pseudo
     CDS             27672..27764
                     /locus_tag="VQU19_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011516271.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(28086..28799)
                     /locus_tag="VQU19_000179"
     CDS             complement(28086..28799)
                     /locus_tag="VQU19_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2479505.1"
                     /translation="MLKRFLALVWLRCQIILSNKSILLQVLVPFAFTYFYKYLMETQG
                     KVNDQQALVLLMMCLPFSLALAVGSPITIILSEEKEKYNLQTLLLSGVKGSEYILSTM
                     FLPFLLTFVIMGTTPLILGVTIVHTFNYITIVLLTSLSIILFYLLIGLTAKSQVVAQV
                     ISLPAMILVAFLPMLSGLDKTVAKITDYSFMGLFTKFFTKWEGFSWNKTLIPNLTLLI
                     WIVLLLTLITITIRKKKIS"
     gene            complement(28792..29487)
                     /locus_tag="VQU19_000180"
     CDS             complement(28792..29487)
                     /locus_tag="VQU19_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2479506.1"
                     /translation="MTGQFLADKGQSIILGQKSQNLTSGELKRIGLVSDTSGFYEKMS
                     LYNNLLFYSKFYNISKSRVDNLLKRVGLYDSRKMVAGKLSTGMRQRMLLARALINKPA
                     VLFLDEPTSGLDPTTSRTIHELILELKTAGTTIFLTTHDMNEATLLCDYVALLNKGKL
                     VEQGAPSELIQRYNKDKKIKVTDYNGNQITFDFTSLEQVSQADLENIFSIHSCEPTLE
                     DIFITLTGGKLNA"
     gene            complement(29827..31159)
                     /locus_tag="VQU19_000181"
                     /pseudo
     CDS             complement(29827..31159)
                     /locus_tag="VQU19_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812020.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
     gene            complement(31143..31941)
                     /locus_tag="VQU19_000182"
                     /pseudo
     CDS             complement(31143..31941)
                     /locus_tag="VQU19_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001824573.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M50 family protein"
     gene            complement(32731..33930)
                     /gene="divIB"
                     /locus_tag="VQU19_000183"
     CDS             complement(32731..33930)
                     /gene="divIB"
                     /locus_tag="VQU19_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HET2479507.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEKEEPES
                     KEKEEQDKKLSKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVVDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESNRNQT
                     TQRSSRR"
     gene            complement(33940..34998)
                     /locus_tag="VQU19_000184"
     CDS             complement(33940..34998)
                     /locus_tag="VQU19_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HET2479508.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVCWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLSKVEHVGA
                     VAKVSDQKNPEPDELVDIQSHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQLENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            complement(35000..36352)
                     /locus_tag="VQU19_000185"
     CDS             complement(35000..36352)
                     /locus_tag="VQU19_000185"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HET2479509.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQSLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGSFSEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLTSKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRGVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            complement(36456..37097)
                     /locus_tag="VQU19_000186"
     CDS             complement(36456..37097)
                     /locus_tag="VQU19_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2479510.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTFL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNCVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTTSLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            complement(37099..39120)
                     /locus_tag="VQU19_000187"
     CDS             complement(37099..39120)
                     /locus_tag="VQU19_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HET2479511.1"
                     /translation="MKKLFILLSTFFLSFFLAWIIVLRAPQYLYASYDSVSLLRVKKD
                     TQEPTREVFEQELENFANSEQSLIARRIVEPSKDGTTHFTYATYGQGTLPKEFQEASQ
                     ESRERSDPLNSYLLLSGSLTKEKLADKLGDLGYKASADRKIPPYFLAFRILLNPLILI
                     SLAIFGLSFFALVIITRIKEMRAAGIKLFSGQTLLSIMGHSLSTDIKWLLLSALLSFL
                     GGGVVLFSQGLFYPILLATYGFGISFYLLFLLAISILLMLLYLMSLSYKALVPVIKGR
                     LPLKRLMILTLLCQLVAVFTVGYAVKTGLMSYQRLKELEISKQAWQDRADYYQISFGL
                     GDRGKDTENQSKWYAFAKEAIEEEQALYVKDNLLHFANPQGKNEQGETLDTYSPDANT
                     LYVSPSYLDKEKVVVDAETKQKLAHLQKGEFILLLPEHLRSREAELKKVFEERLSYYG
                     KSGEEASAPLDYEMKAHVSYLSMGEKRFVYNNGENPVSTQYLTDPILVVFTPTSTGDS
                     FISLSSWSINAGKQLFIKGYESGLELLKKAGIYEQVSYLKEGRSVYLTRYNEVQTETA
                     TLILGAIVGIASSLLLFYSVNLLYFEQFRRDILIKRISGLRFFETHAQYMVSQFASFV
                     FGASLFILSSRDLVIGLLTLLVFLASAVLTLYRQAQKESRVSMTIMKGK"
     gene            complement(39191..39490)
                     /locus_tag="VQU19_000188"
     CDS             complement(39191..39490)
                     /locus_tag="VQU19_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HET2479512.1"
                     /translation="MKTKKHRLLALALISSFTLLGAASAAVQYPDGGVWTYGEGSGGG
                     WAFSNYYHGKKYHYSSLVSRWNSHSDKGEASAGKTSYAWIWTKWGEQVAFYCDYD"
     gene            complement(39856..40110)
                     /locus_tag="VQU19_000189"
     CDS             complement(39856..40110)
                     /locus_tag="VQU19_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HET2479513.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     gene            complement(40130..41971)
                     /gene="typA"
                     /locus_tag="VQU19_000190"
     CDS             complement(40130..41971)
                     /gene="typA"
                     /locus_tag="VQU19_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HET2479514.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            42133..42858
                     /locus_tag="VQU19_000191"
     CDS             42133..42858
                     /locus_tag="VQU19_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HET2479515.1"
                     /translation="MRLDNLLAQEKVSRKAMKQALLRGEILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVQVNELLTPDHIQAFQKGIVFLDGTVC
                     KPAKLEILSASPSLSQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLA
                     ESNYRPLNQKELQIIKNYLEMSR"
     gene            complement(42898..43125)
                     /locus_tag="VQU19_000192"
     CDS             complement(42898..43125)
                     /locus_tag="VQU19_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2479516.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLDYKIEKILNILGIVISVVNWIVAIALIFR"
     gene            complement(43214..43594)
                     /locus_tag="VQU19_000193"
     CDS             complement(43214..43594)
                     /locus_tag="VQU19_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET2479517.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            complement(43594..43863)
                     /locus_tag="VQU19_000194"
     CDS             complement(43594..43863)
                     /locus_tag="VQU19_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HET2479518.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            43927..44835
                     /locus_tag="VQU19_000195"
     CDS             43927..44835
                     /locus_tag="VQU19_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HET2479519.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            complement(44889..45644)
                     /locus_tag="VQU19_000196"
     CDS             complement(44889..45644)
                     /locus_tag="VQU19_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HET2479520.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEADAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(45665..46594)
                     /locus_tag="VQU19_000197"
     CDS             complement(45665..46594)
                     /locus_tag="VQU19_000197"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HET2479521.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTDASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            complement(46609..47232)
                     /locus_tag="VQU19_000198"
     CDS             complement(46609..47232)
                     /locus_tag="VQU19_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HET2479522.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     ESDGFGRIFSENEEKISDDLLFEIAQIFSHQLVFEESGKIYMKPVKDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            complement(47225..48463)
                     /gene="hflX"
                     /locus_tag="VQU19_000199"
     CDS             complement(47225..48463)
                     /gene="hflX"
                     /locus_tag="VQU19_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HET2479523.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            complement(48456..49340)
                     /gene="miaA"
                     /locus_tag="VQU19_000200"
     CDS             complement(48456..49340)
                     /gene="miaA"
                     /locus_tag="VQU19_000200"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HET2479524.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKCFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEDIHSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQEILYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTLEEARESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            49461..49631
                     /locus_tag="VQU19_000201"
     CDS             49461..49631
                     /locus_tag="VQU19_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HET2479525.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            complement(49679..50518)
                     /locus_tag="VQU19_000202"
     CDS             complement(49679..50518)
                     /locus_tag="VQU19_000202"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HET2479526.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPIITLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(50615..51574)
                     /locus_tag="VQU19_000203"
     CDS             complement(50615..51574)
                     /locus_tag="VQU19_000203"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HET2479527.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENTFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            complement(51701..52699)
                     /locus_tag="VQU19_000204"
     CDS             complement(51701..52699)
                     /locus_tag="VQU19_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET2479528.1"
                     /translation="MNKRLFLKMSLVTLPILALFSQPVLAEENIHFSSCKEAWANGYS
                     DLHEGEPGYSAKLDRDHDGVACELKNAPKGAFKAKQAATTQTDTTSSTASGWVKQDGS
                     WYYFDGNGNLVKNAWQGNYYLKADGKMAQSEWIYDSSYQAWYYLKSDGSYAKNAWQGA
                     YYLKSNGKMAQGEWVYDSSYQAWYYLKSDGSYARNAWQGNYYLKSDGKMAKGEWVYDA
                     TYQAWYYLTSDGSYAYSTWQGNYYLKSDGKMAVNEWVDGGRYYVGADGVWKEGQASTA
                     SSSNDSNSEYSAALGKAKSYNSLFHMSKKRMYRQLTSDFDKFSNDAAQYAIDHLDG"
     gene            complement(52749..53366)
                     /locus_tag="VQU19_000205"
     CDS             complement(52749..53366)
                     /locus_tag="VQU19_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET2479529.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGAALTLELSSYDLPNLRALILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKTLMVGVSEELKTLDLTDIAGTCSYPTLLICGSKDKPNL
                     SSMKALHRLLTDSQFQIIPDGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            complement(53367..55088)
                     /gene="pabB"
                     /locus_tag="VQU19_000206"
     CDS             complement(53367..55088)
                     /gene="pabB"
                     /locus_tag="VQU19_000206"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HET2479530.1"
                     /translation="MHRKTVIDFRTLGERYTFAQPIKELKTRNVEEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDSVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLSANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANRDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGELLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQYLLETGQVEEKVLTLADLTQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            complement(55157..60844)
                     /locus_tag="VQU19_000207"
     CDS             complement(55157..60844)
                     /locus_tag="VQU19_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET2479531.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGAMGLVVLPSAGAVDPVATLALASREGVVEMDGYRYVGYLSGDILKTLGLD
                     TVLEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEETPKEEAPRTEESPKEEP
                     KSEVKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKSEEKVAVKPESQPSDKPAEES
                     KVEPPVEQAKVPEQPVQPTQAEQPSTPKESSQEDNPKEDRGAEETPKQEESTPDTKAE
                     ETVEPKEETKTAKGTQEEDYVGEALVPEQLPEYKVTEGTLVEESTTELDYKTETTEDP
                     TKYTDEETVLRNGEKGSQVTKTTYKTIGGVKTDQVLSTSTEVTKEPVNQQVIRGTKPI
                     EGTTVETREEIIPFETKEQEDDTLKRGTRQVTQEGVNDKKQITETYKTIRGEKTSDAP
                     TITETVIEKPQDKIIKNGTKELEKPTLEWAKTDKDVLKKSATASYTLTKPAGVEIKSI
                     KVALKDNTGTVVKEVTVEENNLQATLDNLKYYQGYTLSTTMVYDRGNGEETEILEDKE
                     VQLDLKKVEIKDIKETRLMKVDENGNETDSSLLETVPENLTSYYLKITTNHNKVTRLA
                     ITNIEEVTEEETSLFKVTASAPDLIQRDSNNSLSQTYTYYIEKPKASQNNVYYNFKDL
                     VDAMQKNPNGEFKLGSDLNATNVPTPSKSYVTGKFTGHLTSVDGKHFSIHNTARPLFD
                     RVEGGSIKNINLINVNINMPWANQLASLAQTVKNATVENIKVTGTIVGNNNVAGILDK
                     LDDAGIMTNVAFIGKVQSVGDKGWNLAGIASEIYRGNLNKAYADVELKGLNTRAGAIV
                     GHLAHDFNPRDVGAWSNVRNSVAKGTIDVARGDVGGLIGKDWPWGTIDNNISLVNVKR
                     GDIFFGSNDMDDEFVSNWIKPNNATVIGVSSGDKTHKQSSKIKEISQVEADKKIKDMG
                     ITADTFEVTEHLVDKLNRRILRDEEYKTIQDYNANRELVYRNVEKLQPFYNKEWIVNQ
                     GNKLTTDSPLMNKEVLSVTAMKGNDFITDLTDADHIMVHYADKTKDIFTISPKDSQVK
                     QVKEYSVAELGEVVYTPNMVVKDRADLISAIEGILSPIELQSDPIYQRLGRTGDNRVN
                     AIKNLYLEESFKEVKDHLNTFVTKLVENEDHQLNTDEAAKRALIKKIEDNKAAVLLGL
                     TYLNRYYGVKFDNFNIKELMLFKPDFYGKNVSVLDRLIEIGSKEDYIKGSRTQESFRE
                     VVAKNTLSGNLHDFLTYNMKLFTNETDINVWFKKAIENNAYVVEQPSTNPAFANKKYR
                     LYEGLNNGQHGRMILSLLNLKDAHLFMISTYNTISFSSFEKYGKDTEEKRESFKSEIN
                     KRAKEQVNYLDFWSRLATDNVRDKLLKSQNVVPTPVWDNHGAPGGWPDRFGHRKDKPD
                     YAPIREFFGRIDKYHDYKYGYGAYAYIFADPQPMDAVYFVMSDLISEYGTSAFTHETT
                     HVNDRMAYLGGHRHRQGTDLEAFAQGMLQTPAEHGHQGEYGALGLNMAFERSNDGNQW
                     YNPDPTKLQTRDQIDHYMKNYNEAMMMLDYAEAEAVLPKVKGDNSKWFKKIDRETRRP
                     MDRNKLSGPHQWDKVRDLIDAEKTTNLETIDDLVNNNFMTIHGNPGNKVFHPEDFGTA
                     YVNVNMMAGIYGGNTSQGAPGSLSFKHNAFRMWGYYGYEHGFIDYVSSKHQGAANKEN
                     NGLLGDDFIIKKVSNNQFSNLEDWKKQWYGEVLTKSKKGFAPIEINGTQISTYEQLKT
                     MFDEAVTKDLTELNDSSIKDKYRNTVVLKSKVFKALLKNTDGFSGDLFTAPQA"
     gene            complement(60866..61429)
                     /locus_tag="VQU19_000208"
     CDS             complement(60866..61429)
                     /locus_tag="VQU19_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HET2479532.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGVLFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFDLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALASRPKLIGGARAHYPQDAIRKS"
     gene            complement(61545..63236)
                     /locus_tag="VQU19_000209"
     CDS             complement(61545..63236)
                     /locus_tag="VQU19_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET2479533.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            complement(63233..63970)
                     /locus_tag="VQU19_000210"
     CDS             complement(63233..63970)
                     /locus_tag="VQU19_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2479534.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
BASE COUNT        19312 a        13918 c        11319 g        19611 t
ORIGIN      
        1 gctttttgaa agcagatgag tattatatgc aatttcttta tataaaaaga ccggattgct
       61 ccgatctttc aatagttcat attctcaatt tctattttaa aaatagctaa ggttaacgtc
      121 aaatgactac gcgacctatt tcatacgata aaaatcaagc actagaccag caggtccttg
      181 aactaataag gactctgttc cccaatcggt tacagttggt ccgtgtaaaa cctttatacc
      241 aagctcattc aaccgtttgt agttctggtc tacatcctca acctcgatat gaataatgat
      301 tcctgactga aagttttcca aaggaaccaa atgattttgt gacaacataa ggcagtgact
      361 accaatcgta aactgagcaa aaccatcatc agcataatct gcctttttat ccaaaatatg
      421 ctccaagtca gcacagactt ggggaacatt tgaaacgata atatctaatt gatttaaatt
      481 catttactct cctccataaa aagaccgaat tgctccgatc ttttaaagtt ctgctctatg
      541 aaaatcaaag aataaagtct acaagtttca tatttgattt tcggcgagag gaattattta
      601 attgcgcgtg attgcaatcc ttcttcttcc aagaagagac ggaatggtac gagttcttct
      661 gcttcgtatt tttccttgaa ggctttgata gcttcttctg agtgaagttt tggatccaat
      721 tcaagtactt ctactggaag tggacggtgt tgagtgatgc gagcatcgat gacaacagtt
      781 ttaccttctt tgttcaattt aacagcttct gcaacaactg catcgatgtc ttcgatacgg
      841 tcaactgtga atccaacagc tccttgagct tccgcaattt tagcgtagtc agcgtttgtg
      901 aagtctacac caaacaagtg tttgtttgta tcttcgtatt tgttcttgat gaagccgtac
      961 tcagcatttg agaagacaag gttgataact ggaaggtcgt attgaacgtt tgtgataacg
     1021 tctgggtagc acatgttgaa tgctccatca cccatgatgt tccatacttg gcgatctgga
     1081 ttgtctttct tagcagcgat accaccagga agggcaatac ccattgtcgc aaagagcgga
     1141 gatgtacgcc acatattctt aggtgtcatg tgaaggtgac gagtagatgt ttgagtagtg
     1201 ttacctacgt cgattgagta gatagcgtct tgatcagcat gtttgttgat tgcattgtaa
     1261 acttgataca attgcaattc accctcagtt ttaccttcga gtttgttcat gtaatcacgc
     1321 cagttttggt tgttcttaac gtttgcacgc caccatggag ttgattcaac tgggtttact
     1381 ttgtcaagga tagctttagc tgcttgacca gcatcaccaa ggattgaagc gtcaagggca
     1441 tgacgtttac caagtttgta agggtcgata tcgacttgga tgaatttttc agtgttcttg
     1501 aatgcttcgt aaacttcagc aaatgggaag tttgaaccaa ggaaaagaac tgtgtctgct
     1561 tcaaagacca cttcgttggc tggtttccaa ccaacacggt aagcagaacc tgtcaaacct
     1621 tcatagttcc attcgaaagc ttcaaagttt ttaccagttg tgatgattgg tgctttgatt
     1681 ttacgtgaca attcagtaat cacttcacca gctttaacac caccaaatcc agcatagata
     1741 actgggcgtt cagcattgtt caagatttca acagctttgt cgatttcaac ttcgttcaaa
     1801 gcaggagcga tgaatgagcg ttcgtatgaa cctgaaccgt agtatgagtt ttcgtcgatt
     1861 tcttggaaac cgaagtttac tggaatttca acaacagctg gacctttttt agaaattgca
     1921 gcacggcagg cttcgtcaat tacttttggc aattgctcag cgtaagctac acgtttgttg
     1981 taaacagcga taccgttgta cattgggttt tggttaagct cttggaaagc atccatgttc
     2041 aattcgttaa ctggacgtga tccaaggatc gctaggaatg gagtgttatc catagctgca
     2101 tcgtaaacac cgttaatcaa gtgagtcgca cctggaccac ctgaaccaac tgcaaccccg
     2161 attgagccgc cgaatttagc ttgcataacc gctgcaagag cacctgtctc ttcgtggcga
     2221 acttgtaaga agcggatatc tttgtcttca gccaaagcgt ccatcaatga gctgagtgtt
     2281 cctgatggga taccgtagat tgtatctacg ccccatgttt tcaatacgtt aagcattgct
     2341 gcagatgcag taattttccc ttgagtcata atgataactc tccttcaatt tttttagatt
     2401 tggagaatac gattacatag aattggaaac gttctccaaa tttttactat tccactgtat
     2461 catatttatg ctgacttttc taaaaatctg ctcaaaactc tctattctct attctaatac
     2521 agttttgaaa gttctgtcat ttctgtttta taacaaagaa atctagtcat tacttttagt
     2581 ctattttact aaaatttaac agaagggaac tggtcagaac agatacagaa ctaaaggcca
     2641 tggctagacc tgccaattct gggttgagag ccagtccaac acctgaaaag actcctgctg
     2701 caatcggaat tccgacaaca ttgtagataa aagcccagaa aagattgagt agaattcgat
     2761 gaaaggtttt cttactcata tcaaaggcac gaaccactcc taaaagatta ttggttgtca
     2821 acaccaaatc tgctgactcg atggcgatat ctgttccagc tcccatagca atccccacat
     2881 ctgctacact aagggcagga gcgtcattga taccgtcccc aacaaaggct actttccctg
     2941 actgttgcag tttatggatt tcatgggctt tttcttctgg caagacgcct gcaatgacct
     3001 cttcaattcc gatttgatct gcaatagcac gcgccacacc agcattgtct cctgtcagca
     3061 tgactgttcg gagaccacgt ttttttagct gactgatggc tagcttagca ttttccttag
     3121 gaatatcttg caaagcaagc aagcctttga tttcattgtc aacagctaag aacacaactg
     3181 tcttagcttc tttttctagt tcttctagtt tatcttgata agtattagaa atatccatac
     3241 catccagcat tttagcattt ccaagtaaaa cttgttttcc attgattcgc cctgaaacac
     3301 ctttcccgtg caaggactga aaattttcaa cagtttgaaa ctcaagtcca gcttcactcg
     3361 ctcgcttaac gatagcctca gccagtgggt gttgagaagc atcttccaag gaggctgcca
     3421 atccaaacac ttctacttcg tcgccgatga tatctgttac cacaggtttc ccttccgtca
     3481 aagtcccggt cttatcaaag acaagagttt gaactttctg gatttcctgt aagacagttc
     3541 catttttgag gagaaccccc atcttggcac tacgtcctgt ccccaccata agggctgtcg
     3601 gtgttgcaag tcccaaggca caaggacagg cgataatcaa aaccgccact ccgtagagaa
     3661 gagaggacac aaagctagct ccaagcacga ccacactatc cctgagcaag acgaaccaaa
     3721 cccaaaaggt catgattcct aaaatgacaa ctactgggac aaaaatccct gaaatcttat
     3781 ccgtcaagtc ctgaatcggc gcacgacttg tctgagcttt cttcacaaaa tccacaatct
     3841 gagccaaaac agtctctgag ccaacttttt ctgctctaaa gacaagcgtt ccactatgat
     3901 tgatggttga gccaatgaca gtatctccaa ctgtcttgtc cacaggcaga ctctcacctg
     3961 tcaccatgga ttcgtcaata ctagagacac cttctactac gacaccatca acagcaatct
     4021 tttcaccggg acgcactcga atcaggtcgc ctaccttgac ttgttccaaa ggaacttgga
     4081 cataactatc atcactcaag acttctgcgg ttttagcttg caagtccagt aatttctcca
     4141 cagcttggga cgtatttttt ctcatttttt cctcaaaaac tgctcccaaa agaacgaaaa
     4201 agaggataaa tccagcactt tcgaagtaaa cagggagacc agcaaagaga gcaactaggc
     4261 tatagaaata agccactaga gttcccagcg caaccaaggt atccatgttg gcattgtgct
     4321 ttttaaaact ggcccaagca ctctggatat atggcttacc tgcaactaac ataataggcg
     4381 ttgttgctag aaaggttccc caatgcatga cttgatgact aatgctacct gtcaacatcc
     4441 caatcatgag aatcacaaga ggcacagtaa agatactagt aatccaaaaa cgttgcagga
     4501 gagatagaga ttttcgagtc ttctcaacga ctatatagct tcccttttgc atcttcatgc
     4561 cacaagaaaa ttcatgtcgc cctaattctt gaggtgtaaa acgaatgact ttctcctcat
     4621 ctacgccgat tggttccaag ataccttctt cttcaaacag aatttcctta taacagtttg
     4681 aaggagtagc acgatgaaag gtaatctcag ctggaattcc cttttgaagc tggatatggg
     4741 ctggatgata gcctttttca gctcggatac ggattttttg aatgccattt tctaagcttg
     4801 ctttcacaat ttctgtcata gtctccacct actctacaat catcttgccg tgcatcatgt
     4861 tcataccaca agcaaagcca aactctccaa cctgctcagg cgtgatttcc actacatact
     4921 cttcccccat tggcaggttc gcatgtacac caaaatctgg aaaaacaatt tgatccagac
     4981 atggtgaagg atccttgcgg tcaaagacaa tgcgtgctgg cactgatttc ttgaggacaa
     5041 tcaactcagg agtatagcct cccatgactt ccactcgaat ctcttggtat ccgttttttt
     5101 gctgggcttt ttgtccagat ttttcaggct ttttgaaaaa ccaaaacaag ataaacgcga
     5161 taagggcaat acaaataatg gttacaatac tatttaacat gacgtctcct ttacatacaa
     5221 ttacatctta cttctgttac agcacttgat ttcttctctg aaatcacagc ttccaagtct
     5281 tccaagtcag tctgagtaaa ttcacattct acaatcaagt cagccaacaa attcctaatc
     5341 ctacgggaac aaaccttgtc tttgatatct tggacaagta aatcccgact ttggtctaga
     5401 gttaaaaggg ctgaataaac aaaggacttg ccttcttttt tccgagtcag acactctttc
     5461 tcaaccaaac gagccaaaag agtttgaatg gtcgacttgg accagtcgaa ccgctctgcc
     5521 aaaaccctaa tcaaatctgt actggtctgc tccccctgca tccaaataat cttcatgacc
     5581 tgccattctg catctgaaat ctgcattacc atacctccaa aatctacatt tgtcaattac
     5641 actcatcagt atactcttaa aatctacatt tgtcaattat agaaataata ttttcttcga
     5701 aaaatagaat tttaatcatt tgaaaaacga tttgcagtca aatattacta tataaacaat
     5761 aaaaatatgc tatactaaag aaaaaagaaa acaaccacta ggggtgcgta aagctgagat
     5821 taacgactgt tagatccctc tgactcaatc taggtaatgc tagctgatgg aagtggaaat
     5881 gataatgggg actagcagtc ttctattgcc tttctaaaac agactagctt gttcttaaga
     5941 atacaaactt cagttggttg ggaggtttta gatgacttat ttacccgttg ctttgaccat
     6001 tgcagggact gaccctagtg gtggtgctgg cattatggca gatttaaagt cattccaagc
     6061 gagagatgtc tatggaatgg ctgttgtaac cagtcttgtc gctcaaaata ccagaggtgt
     6121 tcagctaatc gagcacgttt ctcctcaaat gttgaaagcc caattggaga gtgtcttttc
     6181 tgatattcca cctcaggctg taaaaactgg aatgttggct actactgaaa tcatggaaat
     6241 catccaaccc tatcttaaaa aactggattg tccctatgtc cttgatcctg ttatggttgc
     6301 tacaagtgga gatgccttga ttgactcaag tgctagagac tatctcaaaa caaacttact
     6361 acctctagca actattatta cgccaaatct tcctgaagca gaagagattg ttggtttttc
     6421 aatccatgac cccgaaggca tgcagcgtgc tggtcgcctg attttaaaag aatttggtcc
     6481 tcagtctgtg gttatcaaag gcggacatct caaaggtggt gctaaagatt tcctctttac
     6541 caagaatgaa caatttgtct gggaaagccc acgaattcaa acctgtcaca cccatggtac
     6601 tggatgtacc tttgctgcag tgattactgc tgaactagcc aagggcaaga gtctttacca
     6661 ggcagttgat aaggccaagg cctttatcac aaaagctatt caagatgccc ctcaactcgg
     6721 tcatggttct ggtccagtca accatacaac ttttaaagat taagaaaaaa actctctagt
     6781 tcccacttta agggaattag agagttttta tactcttcga aaatctcttc aaattacgtc
     6841 agcttccatc tgcaacctca aaacactgtt ttgagctgac ttcgtcagtc ttatctaaaa
     6901 cctcaaggca gtactttgag caacctgcga ctagctttct agtttactct ttgattttca
     6961 ttgagtatta attaggaaag aatgtcatgc aactttgtta aaaaggcttg cgtttttgcc
     7021 tcaatatctt ctgcttgcat caaatcacgt acaacagcta caccagctat gccagtgccc
     7081 ataagctgat caatattctc cgaagtcaag cctccaatag caactactgg aatggcaacc
     7141 gtttggcaaa ttgttttcaa ggtcgatatc agagtaatgg gcgcattttc cttggtggtg
     7201 gttgggaaaa tggctcctgt acccaagtaa tctgcacctg atttctccgc ttccagagct
     7261 cttttaaccg ttttagcggt gacaccgagg attttttcag gacccaagac tttgcgagct
     7321 accgaaactg gtaattcatc atctccgata tgcagacctg ctgcatcaac cgcaagacaa
     7381 acatccaacc gatcatcgat tatcaagggg acctgatagg catctgttat ttccttgact
     7441 tgttttgcca gttgataata ttgattggtt gtgagatttt tttctcgcaa ttggactatg
     7501 gtaacccctg aacggcaggc cgtctcaact tttgcaagaa agctttccac ggaatcttga
     7561 tagcgattgg ttaccagata tagtctaagt gcttctctat tcataaacct ctcctttgat
     7621 ggtatctagc caattttcat ctcttcttag gagcgaaagc tgattgagta cttggtaacg
     7681 aaattcttcc aatcccattc cttgaacaac tattttctca gcagcgatat tgagataaga
     7741 gactgctaag caagaagctt caaaaccagt ctttccttgg ctgagaaaaa cggctgttaa
     7801 ggctccaacc aagtctcctg tccctgttat ccagtctaat tcagtacagc cattctccag
     7861 tacagcaact tgattctccg aaacaataag gtccttgggg ccagtaacta agaaagacat
     7921 accaggatag gtctgacacc agtctttcaa gacttgaagc aaatcctccg tttcttgatc
     7981 tttagcactc gcatcgaccc caacgccgtg gtgctttaat ccaacaagac ttcgaatttc
     8041 tgacatgttt cctttaagga ccgtaggtct atagtctaaa aggtctttaa ctaagctctt
     8101 acgaatggat gaagtcgtta cgccaaccgc atctactacc atcgggagag aagattggtt
     8161 tgcatacgaa gctgccatgc ggattgcttt ttccttctca gctgacaaat gccccaaatt
     8221 gatgaagaga gcctgacttt gcttagtaaa atcaagaact tcacggggat catctgccat
     8281 gacaggtttg catcccagag ccaaaatccc atttgccagc atctcacaag aaatctcatt
     8341 ggtcatacag tgaatgaggg aactagagcc tataggaaaa ggatttgtca atgcctgcat
     8401 cagtctatcc tttcagcaaa gaaatatcct tgcacttttt taaagaattc ctgcttgatt
     8461 aaaaatctaa atgcaataaa ggaaatcgct gtaccaatca aggttgctcc gaaaaatcga
     8521 ggagtgtaga taaaccaact aagcttagca gccgatcctg taaagagcac cataacagga
     8581 taggaaacaa tagaaccaat aatacctgtt cccacaattt ctcccaaggc agaaaagtaa
     8641 aattttcgac cgtacttata aaagagacct gctagaaggg ctccaaaagt cgctcctgtg
     8701 agagctaaag gcggaatccc ttgagtcgtc atacggataa aggctgtcac tgtagccata
     8761 gccaaggcat aaacaggtcc catcatgatt cccgctagaa tattgactac actggacatc
     8821 ggtgccattc cctcaatccg aaagataggt gtaaggacta catcaagggc aatcatcata
     8881 gataaaatgg tcaatttgtg aacttgtagt tggtgctttc tcatgtttct attcttctcc
     8941 tttttctaaa gactgtaaat cgctcttcca tgtctggtgt tggtaagcca tctcccaaaa
     9001 cttggcttcc atatgaacac tgatgtggaa ggcatctagc attttttgct tatctgtctc
     9061 atcactttct cgataaagct gattgaccag tgctccctcc tctctgatct gttgctctaa
     9121 ctcatccgta atataagttt caatccattg ttgatagaga ggatttggtg atggtttaag
     9181 attaagtgat ttgcctatat catggtataa ccaaggacaa ggaagcaagc ttgcaaaagc
     9241 tatggctaag ttcggttctg caaattgcct ataaatatga gaaatgtaat gataacaggt
     9301 tggagcgatt ggatgttgct ccatttcctg gtcgttgatt tccaattcct tgaaaaattg
     9361 ttggcgaata aataactcac cctccactaa accctgagca ttttgtttca agagtctttt
     9421 catctcttgg tttgaagtct tatcagccaa aagatgatag atttctgaga aagccttcag
     9481 atagtaggca tcctgaatca ggtaatagcg gaaaatggca ggttctaaat tcccctcttg
     9541 taattgtaaa ataaagggat gatgaaagga agcctgccaa gctttcttgg ataattccat
     9601 cgcaatatct gtaaattcca taataactcc tttataaaaa tagactggtt tgaagcaata
     9661 aaaagaaaag caggtagatt aattttgttt ttttaggaat ataaaaagtc cgatagctat
     9721 tcttcaactg tgcatgttcg tcatatccgt aagcagatag agctctcagg taaagatggc
     9781 gccacctaaa gactgtcatc agaaccttac tgtaaatcaa gggcgaccaa aaatgtagtt
     9841 tttgaccacg taataggcaa gcttctttga gggacttgat ttcttgctga atgagaggaa
     9901 aagaattgaa taccacaatc aaggcatagg accaagagcg tgatagcccc ttttgagcca
     9961 agtacaagag aagctctttt agtgaaatag aggaaacaaa gacaaggccg atacaaactg
    10021 tcacaaaggc cctcgttcca agcatgactg cctgtgaagc atctccgtgt aactgaactg
    10081 cccagtagtt ggcaaaagat gggaaaatgg caagtatgat catccaagct aacattttaa
    10141 atcgacggta atagagcata aagagaatac aaaatgcgac taccgaaaga ttcagagcaa
    10201 tcgaaggaat gaaagatgtt tccaaggata aaatcagcaa gaagagactg ataatcggtg
    10261 tctgggttgc tactttgacc atactatctc acctcccctt gggtattgct actctgagat
    10321 gtaagtggtt tggtaatggt cacttctttc acatgccgaa gaccctgact agtcatctca
    10381 atccaataat caaccacaga aatcaaaggg tctaaacgat gactaatgag cagaaaactt
    10441 cttccttgat tcctctcctc cacaatccac ttgcaaaaat aatggcaggc tctatcatcc
    10501 aaacctgcaa aaggttcatc tagcaagatc acggaagcct tactggtcaa gatggtcagg
    10561 agctgaagaa ttttttgctg accaccactt aattgatagg gactcttatc gactgcctgc
    10621 tccaaatcaa aatatcgtaa agcttgaaaa atccgctgat ttctttcaga atcaggtcca
    10681 tctaattgaa gctcctctcg cagactgact cggataaact gcttctcagc ttcctgaaca
    10741 acaccagtca gatcacgata caaactcttt ttctttttca ggaccgaacc cttccaagta
    10801 atgctcccct tatacttttg aaattgaaga atagaccgaa agagggttga tttcccgaca
    10861 ccattgtcac ccaggataca ggaaatccct tgatagaatg tgaaatcagc aattgaaaag
    10921 agggggcgat taccaagctc accagtcaca cggttcatat ggaatagttc cgggctagaa
    10981 gcaacttcct ttgaagcaac ctgtgtcatc tcataggaag ggatttgaaa cacttccctt
    11041 agttttccgt ctcttagctc caccatatgg tcgatatagg ctttatagtc agataaatca
    11101 tggtcgcaca aaataactgt cttcccatca tagaccaact cttttagaat ctccaatatc
    11161 tcgattctgc tcttgcggtc aatggaagcg aagggctcat ccaagagata gaccctagga
    11221 ttcatggcaa agaggacagc cagcgctgct ttttgctttt ccccacctga taagtgatgg
    11281 atgagacggt gcaagatgtc cttgcaacga cattgctgga caacctctgc tattttagaa
    11341 tcaatttcct gaaggtgata gccgatattt tccatggtaa aaaccaactc ctcaaacaag
    11401 ctctccatgg taaattgatg attaggattt tgcaagagaa taccaaccgt ctggacacgt
    11461 tcgacgatag aaagctgact gacctcgctc ccatctatca ggacttgacc gctataggga
    11521 agagaactaa cttgggcaat catttgaaag aggctggatt ttccagaccc actactccca
    11581 actaacaagg taaaggcttg cgcatgaaaa gtaaaatcaa acggctcaga gaagattggg
    11641 gactgaatcg ctcgtagttc cagacccatc tatgcttttc ctccagttgc aaactgatga
    11701 tagagtttga caatggcacg aaccaagatg gtacagaaga aataaacaga aataaaacgt
    11761 accacaagca aggaaaggac aaacggaagg gaaaaggcgt agtaacctaa cttaatgtat
    11821 tcatagacaa agctaacaag cgtaatccca atactattag cagttagaga gagccaactt
    11881 tcatagcgat tcttagttac gataaaacca aattcacttc ccaaaccttg aacaaagcca
    11941 gacaaaagag ctcctagacc aaattggcta ccataaagga cttcagcaag cgcagctagc
    12001 acttctccaa tcgttgcact tccgactctc ggaacaaaga tggcagcaat gggcgcagcc
    12061 atacaccaga gaccgaagag gatttcattg gcaaaggcct gcaaaccaag aggtgttaag
    12121 agtagactga gaatattata cacatatcct gaaccaacga aaaccccacc aaaaaagata
    12181 gacaagaaag caagcaagat aacatctttt aactgccatt ttttcaacat aaaaaactcc
    12241 tttttttaaa gaaaagtggg gcactcaaga agaccgacct aaatactttg tatagcagac
    12301 tgaatttaga acagtacaca agaacactaa aatatttcta gaaattaatt tgaattttct
    12361 aattgatttg ttcgcatctt atttcaatct actatatcat cttcatccag tttcgtaaaa
    12421 gaaaaaactc taattacaga tacaaattag agttcagctt acaagattag acagttcttt
    12481 tcgacatacg aaaaaaacat ttcacatttc ccttcgccag tcttaactgt atcaggttca
    12541 atgggtatca tctcagccta aagcacccca aatgtcttta ttatttaatt atgtgattat
    12601 tataacacac attttatact agttcaagaa attgaactgg aaatacagcc ttgcactcac
    12661 aaagacagca gatctttctt ttgcaaaaaa caaatgacct gtttgatgaa ttagccattc
    12721 aagctgaatc tggacatagc tttttaaaaa aggaaaatcc tacttactta gaatccaagg
    12781 atagatatct attgttcact catttcccga acagtttttt ctatattttt tgcatacgat
    12841 attgccgaaa tgattgaaac gccatccata ttggtcttta taatgtcttt aatatgtttc
    12901 gtctgtatcc caccaattgc aactaaaggc atttgtggca atagttttct catcaattca
    12961 agaccttcat aacctatagt accaccagca tcatcctttg actgggtacc aaatacaggc
    13021 ccaacaccta cataatctac atattcaact tttgattgtt gaaattcttc ttcgtttctt
    13081 atagaaagac caattatttt atctggcatc aattttctaa tttcatcaac accaatatca
    13141 tcttgaccta catgtacgcc atcggcgtca atttccattg ctaaatctat atcgtcatta
    13201 acgataaatg gaacattgta ttttttacaa agttctttaa tttggatagc tagctcaagt
    13261 ttttctaagc cttctaaagc accctcacct ttttctcgaa attgaaataa ggttatacca
    13321 ccttttaagg cttcctcaac gactgtatat agattttttc cttggcaagt agtcgttcca
    13381 caaataaaat atagttttag taattcttta tgaaacatct tacttcactc ttttgaattc
    13441 ctttacatct tcatctgtaa tctcgtataa ggcatttata aattcaactt taaatgtccc
    13501 aggaagatgt ccatttggac gtttttctgc catttctcca gcgatattgt aaaccaacat
    13561 tgctgtttct aatgatttca attcttgacc tttttctagt ccgataaagc ttgctactac
    13621 agctcctaat aagcatcctg tcccaatgac tttcggcatc atagcactac cattatgaat
    13681 cattaccact tctccattaa cagcaatggc atccacttca cctgttacta ctattggaat
    13741 attgaacttc tcatttgctg ctagagcaat ttcgtcaata ttatctacgc ccgcactatc
    13801 tactccttta gatgccacat ctattcctac taaagaggca atctcgccag catttcctct
    13861 aatcgctgct agtttataat tgttgattag atcatctgct actttttttc tatattctcc
    13921 tgctccacag gctacaggat ctaaaactgc tgggacatta tatttctctg caattttcag
    13981 agcagcttgg tataatttcc aattttcatc tgtcaatgtt cctatgttta ttaataaacc
    14041 accagcatac tttaacaaat cctctaaatc tgctggaaac tcactcatgg ctggtgaggc
    14101 gcccagtgct actaatccat ttgctgtgaa attttttact acatcattgg ttatacaaat
    14161 gaccaatggt gctttttctt ttaataattt taaacttgtc atattgaaat ccttcctttt
    14221 cactttatac gatctactga tttcgattta tttctatctt tcgttaagaa tttttttcat
    14281 ttacattgaa tgatttatac tcaatgaaaa tcaaagagca aactaggagg ctaaccgcag
    14341 gttgctcaaa acactgtttt gaggttgtgg atagaactga cgtggtttga agagattttc
    14401 gaagagtctt acctcatcaa atttgtaaat atcatgagcc ttctctagac atcgtaacca
    14461 atatcaaaaa aagctaattc taaagcgact gcttgattcc agcgttgctg aagttctgtc
    14521 aaatcttctc gatttttatc gacacgattg agttcgtcaa ccagaaattg aacccactct
    14581 gcaaagaaag gacctctgtg gagattgatc cattccgaat gaatatagac ttcaggtaaa
    14641 gccaaatctt tagaacccca gtctaaatag agaccttctg caatgaccag catgaccaaa
    14701 agatgggcat agtctgatga agccaccgcc gaatacatta gatcctgaaa ggcttttgtt
    14761 acagggtgca aagtcacttc tagatagtca ttctctgcta cttttaactc tttaaaagcc
    14821 ttttggaaat aaccatcttc atctgcttca agaaagccta gttgcttggc aaaacgaagc
    14881 ttggattcaa gtttatctgc gtgagctacg caggcaccca gcatggataa gaaggcatca
    14941 aagaagtgat aatcttgaat cagatagtcc tttaagacct tattctcaat tgtccccgca
    15001 aaaagttcct taacaaaacg atgattgatt gcagcctgcc aatccttctg actgcttttt
    15061 aataattctc caacagtcaa acctggctga aatgcatagt cttgtgtttc catatttact
    15121 tctcctctct ttacttgtta gtaattaata aaacaccaag aaatatcaag caaaatcgta
    15181 attccacttg atccttttaa agcacatcga gagcatttgc agagagctaa ctaaacaagc
    15241 ctatccagtt tatataaaca aaaaactcca attacaatca agaattagag ttgacttaca
    15301 agattagatc gttcatttcg ccatacgaaa aaacgtttca catttccctt cgccagtctt
    15361 aactgtatca ggttcaatgg gtattatctc agcctaaagc accccaaatg tctctattat
    15421 ttaattactg aaccagtata gcaaaaaatg aaagccctag caagatattt gaccgaaaaa
    15481 tatctttata tataatatat tgaaactaga atagtacacc tctacttcta aaacattgtt
    15541 agaaatcgat ttgactgtcc tgattgattt gtcctattct tatttcattt tactatagtt
    15601 ttcgatagca atttattctt ccaatacacg aagaaaaacc tccacattca gtggaggcaa
    15661 tctgttttat caatacaatt ttaagtcacg agggtcaact gggaaggttg ggttgtatgg
    15721 attgtgacgg agcttaaagt gtttgacatc ttcaatggtc tgagctccag acaattgcat
    15781 aactgtcttc aattccgcat tcaagtgttc aaagacttga cgcacaccga cactaccacc
    15841 gagagccaag ccataaataa cagggcgacc aatagctacc aagtctgctc ctgaagccaa
    15901 ggctttaaag acgtgttgac cacgacgaac accagagtca aagacaatcg gcacacgtct
    15961 atcaactgct tctgccactt cttgaagcga gtcaaaggca gctggtccac cgtcgatttg
    16021 acgaccaccg tggttggtta cccagatacc agaagctcct gcagcaagtg aacgttcaac
    16081 gtcctcacgg cattgtggtc ccttgacata cacaggaaga ccagagtatt cagcgataaa
    16141 ttctacatcg cgtggagaca agcgttgttt agctgatttg taaacaaagt ccattgattt
    16201 accagcacct tctggcaggt attcttcaac aatcggcatg ccaactggga agacaaaacc
    16261 attacgctta tccacttcac gattcccccc tacagtagca tctgccgtca agacaatcgc
    16321 tttataacct tcagccttca cacggtccat gatgtggcgg ttgataccgt catccttact
    16381 aaagtaaaat tggaaccaat ggggtgtccc ttgaagggct tcagaaatct ctggaaggtc
    16441 aacagtagag taagagctgg ttgtataaag agaaccaaac tcatgcacac cacgcgcagt
    16501 cgccacttcc ccctgttcat ttgccaattt atgagccgca acaggcgcca taatgattgg
    16561 tgaagatagt ttttcacctg caaattcaat ctctgtactt ggattttcaa catcgcaaag
    16621 tgtatgagga acgatgagtt tgtggttaaa ggcgcggata ttctctctta aagtgaaagt
    16681 atcttccgcc ccactagcga tatagccaaa tgctgcttta ggaataactt gttgcgccat
    16741 tggctccaaa tcataggtat tgatgaagtc tacatgacct tctgcattgc ttgttttgta
    16801 tgacataaaa tgccctcctt gattaagtaa gcgtttgctt tttactacac aactataata
    16861 actctttttt caatcatttt caagagtttt gcttaaaaac catcttattt tttcatacaa
    16921 tatactagcc ctactttcct taaactctaa actttagtct atattaagtg aatcgttgag
    16981 attttttgct gccaggcatt tgaactactt ttttatttgc ggattctatc tactaatact
    17041 ataaaaaaac aagtgaataa gacaccagaa catcctctaa taggacctat ggacttatat
    17101 cagtcccata tatactgttt aagcaagata ctatcctagt tgacgctaac ttcctatccc
    17161 acttattaat tttttattta tagtgaatct gaacaaatca attggggaat ccaagtcaat
    17221 ttctagtact ttttgaacag tttcagcgta ctatcgtaaa atgaaataaa acatgcacaa
    17281 attgcttagg gaatttaaac caatttctaa caatgtctta gaaatcaaag tgtactattt
    17341 caacttcaat atactacact tcattttctc cttaaattca gtctcttttt gaatcaaaaa
    17401 atcccctggt aagagccaga ggataagaat ttatttcatt gttgggaaga gcaatacatc
    17461 acggatagtt gttgtatcag tgaggagcat gcagagacgg tcgataccga ttcccaaacc
    17521 acctgttggt ggcataccgt attcaagagc ttcaatgtag tcatagtcga tgcctgtcgc
    17581 ttcatcatca ccaagttctt tggctttagc ttgggcttca aaacggctaa gttggtcgat
    17641 tgggtcgttc aactcagtaa aggcattacc gtactcctta gtcatgataa agagctcgaa
    17701 acggtcagta aagcgttggt cttcaggatt tttcttagcg agtggagata cagctactgg
    17761 atgtccatag acaaaggttg gttggattaa agtttcttca acaaactctt caaagaaggc
    17821 attgatgatg tgaccaacct cagtgtagtg tttctcaact ggaactttct tctcagcagc
    17881 gatagtttta gcttcttcca aagtcatgtc ttgccagaaa tcgacaccag taatttctct
    17941 gatagcatcc accatatgaa cacgcttaaa tggttcgtta atcttgattt cagtaccttg
    18001 gtagttgact gggccatcac ctttgactga tttagcagcg tgttggataa tgccttcagt
    18061 caagtccatg atgtcttgga agtctgcata agcttggtaa acttcgatag aagtgaactc
    18121 agggttatga gtagcgtcca ttccttcgtt acggaagata cggccaattt catagacacg
    18181 ttccatacca cccacgataa ggcgtttcaa gtgaagctca gtcgcgatac gaagcaccat
    18241 gtcaatgttt tgggcattgt ggtgggtgat aaatggacgg gcagcagcac caccggcttc
    18301 attatgaaga acaggtgttt ccacttcaag gaatcctttt tggtcaaggt aacgacggat
    18361 ttcagagatg atttttgaac gagtgacaaa gcgttcaaag ctttcacgat tagaaatcaa
    18421 gtcaaggtaa cgtttacggt aaattgtttc aacgtctgtc aaaccatgga atttctcagg
    18481 aagaggacga agagccttag acaagtgtgt gatgtgggtt gccttgatag agagttctcc
    18541 catatccgta cgcatcactt caccttcgac accaaggaag tcaccaaggt ctgctttttt
    18601 gaagatttcg tagttttctt caccgacagc atccttacga acgtagatct gaatctggcc
    18661 ttcgcggtct tgaaggtggg caaaaccaac ttttccttta ccacgtttgg ttatcaagcg
    18721 tcctgcgata gtagctgttt cgtttttatc gtgtaattgt tctttatcga ggttggcata
    18781 tttatctttt aattcttgtg aatttgcagt acgttcaaaa cgttttccga aaggatcgat
    18841 tccttgttcg cggagcgcag ccattttttc acggcgaacg atctgctggt catttagttc
    18901 ttccatatgt tctgtagaca tgggatcctc ctagttttac tcaaaattga atacgatgag
    18961 tcattttttg cgatactccc attttatcat aaataagcaa gaaattcacg gataatcttt
    19021 aaaaactaaa aagaacctga cgctaaaatc actggaaaga agtgaaagta tctcccgccc
    19081 cactagcgat atagccaaat gctgctttag gaataacttg ttgcgccatt ggctccaaat
    19141 cataggtatt gatgaaatct acatgacctt ctgcattgct tgttttgtat gacataaaat
    19201 gtcctcctta ataagtaagc gtttactttg tgtattacaa aaatatctta actctttttc
    19261 aaaactttta aaatattttg tttggaaatt tcagaaattt tatgtctatg ataaaaatcc
    19321 ttataacggc aataaaaaat agatattatc caaagaagat tttaagtgct acaataactg
    19381 tattatttct agatgggagg ttctattttt ggattgatcc attgttgaac aatatctacc
    19441 actatatcaa aaggcattct ttctgacctt gcatattgca gtttggggaa ttttgggatc
    19501 ctttctgctc ggtttaatcg ttagtatcat ccgacattat cgaatccttg ttttggcgca
    19561 agtagcgaca gcctacattg aattgtcacg taatacgccc cttttgattc aactcttctt
    19621 tctctacttc ggtcttcccc gaatcgggat tgtcctatct tcagaagtct gtgcaacgct
    19681 tgggcttgtc tttttaggag gctcctatat ggcagaatct ttccgaagtg ggctggaagc
    19741 catcagtcaa acccagcagg agattggcct cgctattggt ctgacacctc tacaggtctt
    19801 ttactatgtg gttcttccgc aagcaacagc ggtggcactc ccctccttta gtgccaatgt
    19861 cattttcctt atcaaggaaa cctctgtttt ctcagcagtg gctttggccg acctcatgta
    19921 cgtcgccaag gatttgattg gtctctacta tgagacagac attgcgctag ctatgttggt
    19981 agttgcttat ctgatcatgc tgctacccat ctcactggtc tttagctgga tagaaaggag
    20041 gctccgccat gcaggattcg ggaatccaag tactctttca aggaaataat ctcctgagaa
    20101 tcttacaggg attgggcgtt acgattgaga tatccatcct gtctgtcctc ttatccatga
    20161 tgttcggaac agtcatggga atcatcatga cctcccattc tagaatcata cgatttttaa
    20221 cacgattgta tctggacttt acccgtatca tgccccagct ggtgctactc ttcatcgttt
    20281 actttggctt agctcgaaac tttaatatca atatctcagg tgagacttca gctattatcg
    20341 tttttaccct ctggggagca gctgaaatgg gagacttggt acgtggagct atcacttctc
    20401 tccctaaaca tcagtttgaa agtggacagg cactcggctt gactaatgtt caactttact
    20461 accacatcat catcccacaa gtcttaagaa gactgctacc gcaggctatc aatcttgtca
    20521 ctcggatgat taaaaccact tcattagttg ttttgattgg ggttgtggaa gtgaccaaag
    20581 ttggacaaca aatcatcgat agcaatcgcc tgaccatccc aactgcttca ttttggattt
    20641 atggaaccat tctagtctta tatttcgcag tttgctaccc tatttccaaa ctatccactc
    20701 acttagaaaa acattggaga aactaaatgt ctgaaactat cttagaaatc aaggaactaa
    20761 aaaaatcctt cggagacaat cccatcctcc aaggactttc tctagaaatc aaaaaaggga
    20821 agttgttgtc atcctagggc catctggttg tgggaaaagt accctccttc gttgcctcaa
    20881 cggcttagaa agtattcaag gtggagatat tcttctggat ggtcagtcta tcgttgaaaa
    20941 taaaaaagat tttcacctag ttcgccaaaa gattggcatg gtctttcaaa gttatgaact
    21001 ctttccccat ctggatgtct tacaaaacct catcctaggc cctatcaaag ctcaaggaag
    21061 ggacaagaaa gaagtaacgg aagaagcttt gcaattacta gagcgtgtcg gtttgctgga
    21121 taaacaacat agctttgccc gtcaattatc tggtggacag aagcaacgtg ttgcaattgt
    21181 ccgtgccctc ctaatgcatc cagaaatcat cctttttgac gaggtgactg cttcgctgga
    21241 tccagaaatg gtgcgtgagg tgctggaact tatcaatgat ttggcccaag aaggccgtac
    21301 catgatttta gtaacccacg aaatgcagtt tgcccaagcc attgctgacc ggattatctt
    21361 cctcgaccaa gggaaaatcg ctgaagaagg aacagctcaa gccttcttta ccaatccgca
    21421 aaccaaacga gcccaggaat ttttaaacgt ctttgacttt agccaattcg gctcatatct
    21481 ataaaggaga ttcttatgaa actattcaaa ccactcttaa ctgttttagc acttgccttt
    21541 gcccttatct ttatcactgc ttgtagctca ggtggaaacg ctggttcatc ctctggaaaa
    21601 acaactgcca aagctcgcac tatcgatgaa atcaaaaaaa aagcggtgaa ctgcgaatcg
    21661 ccgtgtttgg agataaaaaa ccgtttggct acgttgacaa tgatggttct taccaaggct
    21721 acgatattga actagggaac caactagctc aagaccttgg tgtcaaggtt aaatacattt
    21781 cagtcgatgc tgccaaccgt gcggaatact tgatttcaaa caaggtagat attactcttg
    21841 ctaactttac agtaactgac gaacgtaaga aacaagttga ttttgccctt ccatatatga
    21901 aagtttctct gggtgtcgta tcacctaaga ctggtctcat tacagacgtc aaacaacttg
    21961 aaggtaaaac cttaattgtc acaaaaggaa cgactgctga gacttatttt gaaaagaatc
    22021 atccagaaat caaactccaa aaatacgacc aatacagtga ctcttaccaa gctcttcttg
    22081 acggacgtgg agatgccttt tcaactgaca atacggaagt tctagcttgg gcgcttgaaa
    22141 ataaaggatt tgaagtagga attacttccc tcggtgatcc cgataccatt gcggcagcag
    22201 ttcaaaaagg caaccaagaa ttgctagact tcatcaataa agatattgaa aaattagcaa
    22261 ggaaaacttc ttccacaagg cctatgaaaa aacacttcac ccaacctacg gtgacgctgc
    22321 taaagcagat gacctggttg ttgaaggtgg tcattaactc ttaaaaggga ctggatttta
    22381 agctccaatc cctttttaag attttaccta taacatcctg agtctatcta agatgttcaa
    22441 tctgaacaca gtgtacatac tttatcttct attgcatata ctttatcaca taagatacga
    22501 atatcctctt cactatgact agcaatcaaa attgttgtcc ctttttcact agagagcttt
    22561 ctaaacaatg ttctcatatt ttctacactt gatttatcca aggcattcat aggttcatct
    22621 agtaaaagaa tagagggatt ctccatgatt gcttgagcaa tccctagctt tttcctcata
    22681 cctagcgaat aagttttaac tttctggtct ttttgctcat atagaccaac tattttcagt
    22741 gtatcattga tttcctgatt accaactact cctcgtatgc ttgccaaata ttgtaaattc
    22801 ttaaagccac tataataatt tataaaacca ggttcttcaa tcaaagctcc caaattagct
    22861 ggaatttttc tctcaggaac aatattttcc ccattgatta acacttctcc ataagacgga
    22921 ctatataaac cagctattaa tttaaacaat acacttttcc ctgagccatt cgcaccagta
    22981 attcctataa tttccccctg tttacaacta aagttaaggt tttgaaaaac acatgtcttt
    23041 tttaatttca actcaatatt ttttaatata attatttcat tcattctata aacctcctct
    23101 tttgacgagt gaaatagaaa atgctttgaa aaagaaagac taaaaatagc aactgaagaa
    23161 acaaatctcc ccctacatcc ccattccctc gattcaaaat ataaaataga taattagttc
    23221 gatttcctac aaatagacca ccaaacacaa tcatgagtaa aaagaaacta acgcaagcaa
    23281 agttcatttg tacattcgct cctagtgcgt ataacataaa gcaaaacaag actaacacac
    23341 aagcattcaa agaatcaact ataaacaaaa ctcctatatc ccagtttggt aactgtaaca
    23401 taaattgaat cactagaact tttaccatga ttaaaatgag tccataaaga aaacaggtcc
    23461 aaatctgata cctaatccag agcttaatag aagaaaatcg aatcacttcc ataaagaaat
    23521 cggatgctct tctacgatat acaactgcta gaaaaaatgt atgaataata aaccaatgaa
    23581 gcaaccatat agataagact aaaaaagagt tttgactcag attaggccct tttaaaattt
    23641 ctataacaag tctatcattt ccttctaacc aataccataa tcctaaacaa atcaatatcc
    23701 aaaaaagaac ataaccccaa aagtacttgg tatagattat cttattcaac ctccacatgt
    23761 gactacttaa ctttcccatt tccaactttt acactctcct ccagtttcta tgaacagaaa
    23821 atacagtcaa tggaattatg atagatagta atgtaagcca ataaatcaat gcatacggat
    23881 tggaatttac catatactga aaaattggca ataatccaat tatcccattg ttcaactgat
    23941 aaatccagaa taaggattct acaaataaaa aagtaaacag aaatactaag ctcatgtttg
    24001 attttttaaa ccaagaaaaa ctgctaatag taagtaagga taaaaagaaa tagtatgcta
    24061 tataagagaa aaaaaatcct ataaagaaac tagcattgtt tgcaatactt ataccataaa
    24121 attctcttaa aaaatcaacc tcctttatct ccaaagagaa gctaaaacca ttactaaatg
    24181 caattagaaa aatcaataaa aataaagtcg ccgtccaaat ccccgtacta agagctgcta
    24241 atttgaaact aaaactggta aagtgcttaa ttgatttcag acgaatgcga cactccaacc
    24301 tattaaaata gttattcatc aaataaaaaa agaacaatat atatgtgaac ggaaagcaat
    24361 atactccagt cgtcatatct tgaagtaaaa ctaaaatcca ttctaataca tttggatgga
    24421 ttgaatattg gcgacagcgc aataaatata ctgtactaga taaaacacag gatagcagta
    24481 atataaaata aaccaatact gataaaaaat cttttttgta aaattgaaca aattgtttca
    24541 ttatacatag tcctctgaat gtagaaaaaa tgtaccataa acaaccaaac aactaacaaa
    24601 taaaataaaa gcaagatgcc cactaactaa ggaaagactg atatctttct gatatcccaa
    24661 agctaatgtt gtcacaggtt ctaagtaaga tagccctaaa atagcccaaa aaataccacc
    24721 aaccatcata taggcaactg ggatgaaaat agctcctatt tttttcttca ctagcaaagc
    24781 actagctagt ccaaaaatag agaacacagc gccccaaact ccataccaga gagtcgtcac
    24841 aagactatag agcaactgat tagaatcaaa taattctttt aaggcaccac tataatctcc
    24901 aatataaatt tcctgataag gagtcactaa aagattaatt cctaataata ataaataggg
    24961 gagaaaaaag actagaaaag aagaaataat tgcagtacta cctacaatag ccagatactt
    25021 ctttttagaa attcggcaca attgtgctgt tagaaaatga ctctcagcat cctctattat
    25081 ctgactagaa tagggcagtg tacagataag tgcagctact aggctaatcg gtgaaaatcc
    25141 tcgaatagaa gaagcggcaa aaaaaatcga taaaccttca attttataaa taccattgaa
    25201 agcaaggaaa tttcctaaac tcatgcaaag aagggtcaaa aataaagaca tataaaatcg
    25261 aggtgattga acgactcgta caagattaca aatgaaaaat tccatcctta ctcctcctta
    25321 taataaaaat agggtgtagc attctttttt catgctacac ccacaatcaa ccatctttaa
    25381 ggcttactct gacaagtaag ttaataagaa tctggactcc aagaacctga agtatgaatt
    25441 cttacatgat ttccaaattg tggcgccata gctaatctag taccagaacc aatataattg
    25501 tcaccacctc cattatagta catgacaatc ctagagccag accccaatga atataccggg
    25561 gtaatatctg acccactata ggcgctacga atagaggtat ttaacctttt accgccacca
    25621 gtgctgtcac tattattaat tccagcagag gcgttttctt tctcaagctc actagttgta
    25681 tccgaacccc aacgcggcaa cgttaaatca taatttccaa tctgtctagc taaaactgta
    25741 gggagaaaca aactagatgc aattgtaact acgcaaaaaa ggaatatatt tttcttcttt
    25801 tcatgacatc gtcctcttaa gaagtgataa acaagatagt tgattgatca atttgataca
    25861 tattacattt tcattatatc aataaaagaa agcgttgtca attattttat ttaaaatatt
    25921 gtcatatttt aaataaaatg gtaaaagaga ctcggtagcc tcgtctctct ttatcttact
    25981 gacctaacct tcttgccaat tttcttggtc ttctttaaag cgttttagaa gatcaaggcc
    26041 ctctggcgtg atgtaacctt cttcttgggc tagatggata agctctctat agtttgaaag
    26101 cgtcacaagt ttaacaccag catctgcaaa gttcttatct gcttttggca attggtagct
    26161 gaaaatcgct acaactccaa gtacatctgc tccttctcgc ttggctgctg ctacagcttc
    26221 aagaactgaa ccacccgttg aaataaggtc ttcaaccact accatttttt gaccttgagc
    26281 tacgcgacct tcgatttgat taccagctcc gtggtctttt ggtttgctac ggatgtaggc
    26341 aaaaggcaag tccatcttat cagcaataat ggctccgtgt ggaatccctg ctgttgcagt
    26401 tcctgcaatc acttctactt caggaaaggc ttctttaata gcttccacaa aaccattttc
    26461 aattagggta cgagtttctg gataggctag tgtcacacga ttatcagtgt aaatcggtga
    26521 cttgatacca gatgcccaag tgaagggttc ctctggtttg aggtaaacgg cttggatttt
    26581 caagaggtgg ctagcgatat ctttagcaag tgtcatggta ttctcctttt atttttctaa
    26641 tctagttctt taattccagt tctgtgtcca ttcatccttg atggcatgat aagctgcaac
    26701 aggatcctca gcttgggtaa tgggacgtcc cactacgata tagtcactgc cgatttgata
    26761 ggcatcagca ggtgtcatga ctcgtttttg atctccaact gcaacaccag ctggacgaat
    26821 ccctggtgtc agacagataa aatctggatt ggtagcctgc ttgatgactt gtacttcctg
    26881 agccgagcaa acaacaccat ccaagccagc ttcagctgtc ttcttggcat agtgaatcac
    26941 agactcttgc agactggttt ggatattttg aaactcctgc atctgagctt ctgacgttga
    27001 tgtgagctga gttacagcga tcaatttggc ttgactccca agaccttcac gcgccgcctt
    27061 catcatctct acaccaccag ccgcatggac attagtcata tcgacaccaa gctgagacaa
    27121 gaccttcatg gctgacttga ctgtattagg aatgtcatga agtttgagat ccaaaaagac
    27181 actatgaccc aaacctttta agtaggacac aatctcaggc cccgctgcgt aataaagctc
    27241 catccctacc ttgagataaa ggctttcttc tgctgggaaa agagctaaaa attccttgac
    27301 cgcctcaaaa ctaggaaaat caagagcaat gattggacga tgttctcgca taggtttctc
    27361 cttttacctt tactagtgag agagtctggc caacagaagc cacgaaaaaa ggaacctgcc
    27421 aacagcaagg ttccacgaaa aatgggtagt ctccaccctt tcaccgtcta accttagctg
    27481 cctctctgga ctgctttaaa ggttttctat tattctatta tttctactag cacttgtcaa
    27541 gtaaaaactt agtcacgtat gtgttgactg ctattgaaca cctcacaaga ctctttccaa
    27601 aagaatagtt aaagactttc acttaggaca gagaaaaaga gtttgcttgt taccctttaa
    27661 ttgaacaaat gggaattctg ttttattttg cggatgccta ttcatcttgg caaaggggaa
    27721 gtaatgagaa tgcgaatgga cttcttcgtg agtattttct taaaccgatt tggcaacaat
    27781 taccgaaaaa atccttaatg gtgctttgct agcttattaa tcaccgtccc caaaaatact
    27841 tggattacaa gacaggtttt gaagcactta tagaggaaat ttaaaaatgt tgcatttttt
    27901 attgcaattt atcagttatc ttatcaccca aaacttctgc aattagtatg agcactattg
    27961 ttatttttct tttttcgtac actcaaatca aaatatagca ataagactat tctgtagaat
    28021 tgctgtcaaa aagatcagtt catttttcct tcccacttgt gtttataatc attaaaataa
    28081 ctcaattaag aaattttctt tttcctaata gttatcgtaa ttaaagttaa tagaagaaca
    28141 atccaaataa gtagtgttag attaggaatt agagttttat tccatgaaaa tccctcccat
    28201 tttgtgaaaa acttagtaaa cagtcccata aaactataat ctgttatctt cgcaactgtc
    28261 ttatccaaac cagatagcat cggtaagaaa gcaactaaaa tcatagcagg aagactgata
    28321 acctgagcta ctacttggct cttcgcggtt aaacctatca ataaatagaa taaaatgatg
    28381 gataaagagg ttagaagaac gattgtaata taattaaaag tatgtacaat tgtaactcct
    28441 aaaataagag gagtagttcc cataatcaca aaagttagca aaaaaggaag aaacatcgtt
    28501 gataaaatgt attcggatcc tttaacacca ctcaacagaa gagtttgtaa attgtacttt
    28561 tctttttctt cagacaagat aatagttata ggacttccaa cagccaaagc caaagaaaaa
    28621 ggtaaacaca tcatcaaaag aactaatgcc tgttgatcgt tgaccttccc ctgtgtttcc
    28681 ataagatatt tataaaaata tgtgaaagca aaaggcacta aaacttgcaa taaaatactc
    28741 ttattggaaa ggataatttg acaacgcaac cataccaaag ccagaaaccg tttaagcatt
    28801 tagctttcct cctgttaatg tgataaaaat atcttctaaa gtaggctcac atgaatgaat
    28861 tgaaaaaata ttttccagat cagcctgaga tacctgttct agtgatgtaa aatcaaaagt
    28921 tatctgattc ccattataat ctgtaacctt aatcttttta tctttattat atctttgaat
    28981 gagttcagaa ggagctcctt gctcaactaa tttcccttta tttaataagg caacataatc
    29041 acataaaaga gttgcttcat tcatatcatg agtcgttaga aaaatcgttg tccctgctgt
    29101 tttcaattct aaaattaact catgaattgt tcgagaagtt gtgggatcta gacctgaggt
    29161 cggttcatcc agaaagagta cagcgggttt gttgataaga gctcgtgcta aaagcattcg
    29221 ttgcctcatt ccagtggata attttcctgc taccatcttg cgactatcat ataatcctac
    29281 tcgctttaac aaattatcaa cacgtgattt actaatatta taaaatttac tataaaaaag
    29341 aagattgtta tacagagaca ttttctcata aaatccactt gtatcgctaa ccaatccaat
    29401 tctctttaat tcaccgcttg ttaaattttg agatttttgt cccaaaataa tagattgtcc
    29461 tttatcggca aggaactgcc cagtcagaat attaatcgtt gtggtctttc cagaaccaga
    29521 tggtcctaaa aatctaacct tctttaacag tgaagcttat attatttaaa gctattttat
    29581 caccaaaact ttttgataaa tggctaactt caatcatact cattgcacct cctttatatt
    29641 ctacattttt acttaacatc tatttactta tctttatcaa ataaacgtct taaaaaaaac
    29701 aataacatta agcatataac cgttagcaag attgtttcaa tattattgat aatacgatac
    29761 attctcaagc agtataaaat aattatatat atgcaaatgc tcattatacc tattttttta
    29821 aacatactaa gcctccttgc taaataataa agttatataa taactaagac acactatacc
    29881 taacataata aatatccact ggtaactgaa taaatgttct aaaattaaca agcaaaaata
    29941 aaatctcaaa cgatgaaaaa agccatacta tattttccaa tgatgtttga atatttttat
    30001 tgtagtaagc ataatatata gcaaaaataa tacccaagaa caatactatt aattgtgttt
    30061 ctataacagt gaactgccca atagcagata aaaaagctac tcctcctgat aataagcaaa
    30121 aacaaactga acgaataaat gttttcgctc taatattgtt atctttcact ttattatttt
    30181 tttacaaatt ggacattctc cgttttccag aacatatttt tcttgactta gagcatgatt
    30241 tctcatatta taaacgtaag cgttatctat taggatttca ttataacatc ccagaaatat
    30301 tttaattatt aaattagtca ttatccctcc caaaatagca ggcatctctg gtgtagtcgg
    30361 ccactttgtc ttatcagata aagtgtactt atttatatct ttgtttatat tccgacaacc
    30421 aaagcaagaa ccgatggtag ggatatatat tatcagtaat aagatagcat ccattaaacc
    30481 ctcctgatat gtaggatatc ttatgcgata cagcaaattg attgacaatt tttataatat
    30541 caatgggcgt atcaattgct ttaacgataa aatctatact cccatattcc gcaacaattt
    30601 tttctaattc ttctactgaa gaaactttaa tagaaatagg tactacctga acatctgaat
    30661 tatacttgtg tattttttca gaaagaacat taatcttctc cttaccaaca tccgactctg
    30721 tataaagaat ttgcctattt aaatttgatg gttctattat atcgtaatca gcgacaataa
    30781 gtttcctcac tccatacata cttagactta gagatatata acatcctaag gctcctgctc
    30841 ctaatactaa tactgtttta ttctgtattt tattatactc ttcattataa aataacgaat
    30901 agtaaccttt agttctagaa tatctactat caatatctat ctcatccgaa attaaaattt
    30961 gttcatttaa tagttcaaat gttagtttac tgcctaatac ttcttctatc tctaatagtt
    31021 ccttacaact attaaataga tcgttgataa attcttgcga aatttgaggt tctatagcta
    31081 tttcccgcat actccgacca cgcaaataca ttataccttc ttttttataa gcaaaaacat
    31141 aactatttac gtagaacata tttcgtcctt cctctcatat ataatataga aagcagtata
    31201 gaaacaacca cccctcctat actacgaaca ataatattag gtgtcaaaaa ctgtaatagt
    31261 tgactcaaag ggaaataaat aataacaaat gctattaaaa gttgaactat atattgaaaa
    31321 ttcaagttat tattgttaga attcaagtat cttaaaataa taccactatc atactgaaaa
    31381 aaaggaattg aattaataaa aatcatacct aagttaatga taaaaaataa gagtccaagc
    31441 aatttatacg atgtgaacaa taaaacaagt aaacctgtaa gtgataaaat cgaatttgaa
    31501 gcaattcctg ctaacataat tttcaaaaat tgttttttat tttttaagaa ttgcacccca
    31561 cttaaatcta caaaaaaaag ccaaattaaa caaaagtagc attattccac aatttgggat
    31621 ctcaatttga taattattag caattattgc atgactaaat tcatgtatcg ttgcagacat
    31681 aataacaaca agcaaccaaa ataaaagaat gtttagcgtt attggaaagt tttggaaatt
    31741 agtcaaaata tccgccctat aaatatacat aataaaacat tgcaaaataa gagccaatgg
    31801 gaaaatacca aataggattt tttcaaaatt cttattaaat cttttatagt ttaatttttc
    31861 agataatgtt atattaaagt cccaagatat tttaaaaata tttatctttt ttcgtgattt
    31921 catagaatct ataagtccca ttttactaag aacaatataa aatcttaaat aatatttctt
    31981 ccctactaac actaataagt ccgatatggt aaattcttga cctattagtt gctctaacca
    32041 tttttttcct gtttcccaac taatacatgt ttcttactag atggtatata tagatgatac
    32101 tgtccctcat aaggagtagg taatatctta atcttatcaa caattctcat aacaaaccta
    32161 acctttaata aataaaagag gggctaagta aaacatactc tagtccctca gtccgcaatc
    32221 aataaaataa tgactaattc tattaatctc ttgctgcaag actaatacgg aaaattcaaa
    32281 tgactgtcta aaatgaaatt gaaaaagctt gatgttagta aatgaacaaa cttcaacaac
    32341 cagcaagagc aaggattgct aaaccaaatc cgatacctgt tgcaagtcca gctgaaaaat
    32401 cactaactgg tactgaaatt tcttcaattt cctcaaataa aaagttatct tgcatgatta
    32461 tcactcccta tctttttaac aacaggctat tccaattaag agaactaccc cagttccaag
    32521 taaaactccc ccaaaaattc accatctgta ggggctacga tttcttcaat ttcttcaaat
    32581 aagaatgctt catctgacat atgtgttacc ttcttcataa aaaattattt tgtaatcgat
    32641 tacattgcaa atgtaacata aagaaaaaca gatgtcaaat attaaacgta agaacatggt
    32701 cactaaagaa ctataagaga aaaggtaaac ctagcgacgc gatgagcgct gggtcgtttg
    32761 atttcgattg ctctcttcct cttgtttttt ctgttcttct tcctgttttt tctcggcttc
    32821 cttggcctct tgtttggctt tttcctcagc ctccataatt aatttatccg ccacagtgta
    32881 actgtaaatt ccagcttcca tgtcgaccac actcggttct gacaattgtg gcttaatctt
    32941 actgtaatat ggcagtttct tactcatttc agatagagga accaagactt cgtccgaatc
    33001 attcatggtc aatcgaatta aatcggatgt caccttgctt ggggctaatt ccaccttttg
    33061 gatagccgcc ttgagttctg ggctaatttg agcaagttct gagacaaaaa ccttgatttg
    33121 ttcactatca ttaaagagaa ctgataaata agtttctggt aaactgttca gactcacaga
    33181 actagtctca agctgaccac tggaaagaat aggataatga ttttcaccag aaatatagta
    33241 ggccacaata tcatattcct tgaccttaat agtgaactta gttggaaatt gatagacaag
    33301 ttgagctgat tcaacccaat agttagactt aatctgcttt tcatattttg ccttgtctag
    33361 cagaaggtta atcgtataat ccgaatcctg aatgcctgaa gcctgtcgaa tatcatcagc
    33421 tgtagtttgc accgttccct caacacgaat atctttcatg gtcgcataag gactgagcaa
    33481 gtaggcagag acaatcaata aaagcagact tggaaataaa atcgtgaagg ctcgcaagat
    33541 atggatacca ggaatctttg ctttggctgg tttttccttt gtagcctttt tagaaagctt
    33601 tttatcctgt tcctccttct ctttagactc tggttcttct ttctcttctt tctctttgtc
    33661 agcctctgag gatgctactt tttcttcaga ctcttcctta gctgattctg aatcttcctg
    33721 gtctgtttca ctctcctggt cctgtttgtc ctctgacttc tcagattctt ctcccattcg
    33781 agcttgtctt tccttttcct tctcctcagc tagagccgcc tcttcttcag ccttcttttt
    33841 tagatattct tggtttcgtt tctgccattc tgataactct ttcaattctt cgaggatttc
    33901 tttgtcctca tttttcttat cttttgacat ttactttcct tatgataaat cttttttcaa
    33961 caattgataa aaatctgcta gagatttcaa ttccttagaa gccttcatct tagcttggta
    34021 atcttccttg tgacttagta agtgagaaag cttctcttcc aaactatcca aggtcaaatc
    34081 gctttcttga aggtcttctg catagccttt ttttacaaag taagctgcat tttcaagctg
    34141 gtcaccacga ctagcttcac gaccaagcgg cacaatgaca tgcaattttg ctatcgccaa
    34201 gagctcaaaa atcgtattgg caccacctcg tgtcacaaca atatcagcca attccatcaa
    34261 gggttgatag agatcggtca catagtcaac acgaaaaaga ttttggctca actcattcag
    34321 gctagaatct ccagttagat tgataatatt gtagcgctct gttagttctt tcttatggtc
    34381 tgtcaccaat tggttaaaga cacgagcacc tgcagaaccg ccaacaaaca atacagtcgg
    34441 caatttatga ttaaagtggc tttgaatatc caccaattca tctggttctg gatttttttg
    34501 atctgaaacc ttggccactg ctcccacatg ctcaacctta gacaaactcg aagcttgctc
    34561 aaaggttgaa tacatcttag tcgcaaattt ataggcgatt ttattggcca agcccataga
    34621 caggtcagat tcgtgaataa agacaggcac tcctgacaca cgcgcagcga taacaggcgg
    34681 tactgagaca aagcccccct ttgaaaaaag ggtctgtgga cgaagtcgca acatgataaa
    34741 gagcgattgg acgattcccc agcaaacttt gaagacgtcc agcatatttt gccaagagaa
    34801 atagcgacgc aattttccag tcgcaataga atggaaggtg acatccaaac ctgacttaag
    34861 gatttcttgg tgttcgatac cacgcttgtc cccgatatag tggacttccc aaccatcttc
    34921 gatgaacttg ggcattaaca aaagattgag ggtaacgtgt ccaaccgtcc ccccacctgt
    34981 aaagacaatt tttttcatat tattctttta actccgctac tgtgtcgata aagaggtcgc
    35041 cacgtacttc aaagttagca tacatatccc agctggcatt ggcaggacta agaagaacca
    35101 catctccttg agtcgcaagc tcataggcct tgcgggtcgc atctgcaata tctgtcgcct
    35161 ccacataagc gacaccagcc ttgtctgctg cccgtttgac acgttctgca gattgaccca
    35221 ggatgaccat cttcttgagt ccagtaatgt ctggcaccaa ttcgtcaaac tcattgccac
    35281 ggtccaaacc acctgcaatc aagacgacct tgctgttatc aaatcctgac aaggcttttt
    35341 gagtagccaa gatattagtt gatttactgt cgttatagaa tttaacaccc ttgatgtcat
    35401 ccacaaactg gagacggtgt ttgacaccac cgaaggctga aagagtttcc ttgatggttt
    35461 gattgtccac accacgaagc ttggctacag caatagtcgc aagggcattt tccacattgt
    35521 ggctacctgg aacaccgatt tcattcgctg ccatgactac ttcaccacgg aagtagagtt
    35581 gaccatcttc cagataagct ccatcaacct tttcaagtgt tgaaaatggt acaacagtgg
    35641 cttctgtctt ggaagtcaag tcttttgcca agtcttgatt aaagttcaag acaaggaaat
    35701 cagctgctgt catcttgttc tggatattcc acttggctgc tacatattcc gaaaatgacc
    35761 catggtagtc gatatgagtt ggcatgaggt tggtaataac cgcaatctct ggatggaatt
    35821 cttgaacacc catgagttgg aaagaagaaa gttccataac aagcgtgtcc ttatctgatg
    35881 ctatttgagc aacctgacta gctggatagc cgatattccc tgataaaaga ccatgttgcc
    35941 cagcagcagt caaaacttcc ccaatcatag tcgttgtggt tgtcttaccg ttcgatcctg
    36001 tgataccaat aatcggtgct tctgaaatca aataagccaa ttccacctca gtcaagactg
    36061 gaattccctt ggccaaagcc ttttcaatca tgggattgtt gtaggggata cctggatttt
    36121 tcaccataag ggcaaactct tcatccaaga gttccaaagg atggccacct gtaatgacct
    36181 tgatcccttc ttccagcaaa ctttgggcag ctggattgtc ctcgaaaggt ttcccatcat
    36241 ttactgtcac aatggcacct agcttgtcca acaaacgagc tgcagattca ccagacttgg
    36301 ccaaacctaa aacaaggact ttcttatttt taaattgatc tattactttc atgtctcgaa
    36361 ctccatttct actcctacta ttttaccatt tttatggaaa taaaaaagcc acaaagtgtg
    36421 tttgtgactc tttcttctaa ctgaatctta ccatatcatc tatgtgataa atcggtaact
    36481 cgaatgacct gatccacttg ttcccaaata agaggattgt gggtcgcaat aataatggtc
    36541 cgattcggat tttttaaaga ttctaggatg gaaagtaatt cctcagagtt tttggggtct
    36601 aaggaagtgg ttggttcatc tgcgaggatc aaaggtggat cctttaaaat tatcttcgct
    36661 aatgcaacac gttgtgcttc tcctcctgat aactcaaata taggttgctt caaatccaaa
    36721 taagagaggt ttacacagtt tagagcttgt ttcatcaaag agattttctc tttttccttc
    36781 aactttttac caactaaacc cagattgaga ttctctttga cggtttggct ttcaattaag
    36841 ccaaaatctt gaaataagta tcccaagtaa tctctaaaga aaacagaagg cttgatgtcc
    36901 ttaagagaag taccatcata gatgatttgt cctttgtcat atggctctaa tcgtccaatc
    36961 atattcaaga atgttgtctt accacagcca cttgtaccga ttaaggcata aattttccca
    37021 ccttcaaaat gaagatttgt atctgaaaat agctgacggc ttccaaattt tttagatata
    37081 ttctttagtt caatcatcct attttccttt cataattgtc atagaaacac gagattcttt
    37141 ctgcgcttga cggtaaagcg tcagaactgc actagctaga aagactaata aagtgagcaa
    37201 gccaatcacc aagtctcgac tgcttaaaat aaagagacta gcaccaaata caaaactggc
    37261 aaattgacta accatatact gagcatgtgt ttcaaaaaat cgtaaacctg aaattcgttt
    37321 aatcaaaata tctcggcgga attgctcgaa atatagaaga ttgacagaat aaaatagtaa
    37381 taaggaacta gctatcccca caatagctcc taagattaaa gttgctgttt cagtttgaac
    37441 ttcattataa cgagttagat aaacacttct tccttcttta agataggata cttgctcata
    37501 aattccagct ttcttcaaga gttctagccc actctcatat cctttgataa agagttgttt
    37561 tccagcattg atagaccaac tagataagga tataaaacta tcacctgtag aagtcggcgt
    37621 gaataccact aaaatcggat cagtcaaata ctgagtagat acgggattct caccgttatt
    37681 ataaacaaac cgcttttctc ccattgaaag ataactaacg tgcgctttca tctcataatc
    37741 caaaggagca cttgcctcct caccagattt tccataataa ctcaatcttt cttcaaaaac
    37801 tttcttaagt tctgcttctc gagagcgcaa atgttctggg agcaagagga taaactcacc
    37861 tttttggaga tgggctaact tctgtttggt ctcagcatct accacgacct tttccttgtc
    37921 caaataactg ggactaacat agagcgtatt agcatctgga ctataggtat ccagtgtctc
    37981 tccctgttca ttttttcctt gtggattggc aaaatggagc agattatcct ttacataaag
    38041 agcttgttct tcttcgattg cttccttggc aaaggcatac cacttgctct gattttctgt
    38101 atcttttcct ctatcaccta agccaaaaga aatttgataa tagtctgctc tatcctgcca
    38161 tgcttgtttt gaaatttcaa gttctttcaa tcgttggtaa gacatcaaac ctgtcttaac
    38221 agcgtagcct actgtaaaga cagcaaccaa ctgacacaat agggttaaaa tcatcaggcg
    38281 tttaaggggt aatctcccct taataacggg aactaatgct ttgtaactca aactcattag
    38341 ataaagaagc attagtaaaa ttgaaatcgc caataaaaac aacagataga aactaatccc
    38401 aaaaccatag gtggctaaca agataggata aaacaaacct tgactaaaaa gaacgactcc
    38461 cccacctagg aaggaaagga gggctgatag aaggagccat ttgatatcag tagataaaga
    38521 atgccccatg atggataaga gagtctgacc agaaaagagt tttatacctg ctgctctcat
    38581 ttccttaatc cgagtgataa tcactaaagc aaagaaagat aagccaaata ttgctaaact
    38641 aattaaaata aggggattta gtaatattcg aaaagcaaga aaatagggcg gtatctttcg
    38701 gtcagcactt gctttataac ccaaatctcc taatttatcg gcaagctttt ctttcgtcaa
    38761 ggagcctgac aaaaggagat aactatttag cggatcacta cgttcacgac tttcttggct
    38821 agcttcttgg aattcttttg gtaaagttcc ctgaccataa gttgcataag taaagtgagt
    38881 cgtcccatcc ttactcggct ctacaattct tctagctatt aaactctgtt ctgagtttgc
    38941 aaaattctcc aattcctgtt caaatacctc acgcgtcggt tcctgagtat cttttttgac
    39001 acgaagtaaa gaaacggaat catagcttgc atataaatat tgtggcgcac gtaagacaat
    39061 aatccaagca aggaagaagc tgagaaaaaa agttgataat aatatgaata gtttcttcat
    39121 agtagactcc ttgtaaacaa aattccccct gtaatttctt acaaggggaa cgatttaaat
    39181 caatgaacga ttagtcataa tcacagtaaa atgctacttg ttctccccat ttagtccaaa
    39241 tccatgcata ggaggttttt ccagcagaag cttctccttt atctgaatga ctattccatc
    39301 tacttacaag agaagaataa tgatattttt taccatgata gtaatttgaa aaagcccaac
    39361 cacctcctga accttctcca tacgtccata ctcctccatc tggatattgt acagcagctg
    39421 atgcagctcc caataatgta aaacttgaaa taagagctag agcaagtaat ctatgttttt
    39481 tcgttttcat tttatttttt ctttcaaaaa aagcacacct tgagcaacaa tgcaacaaaa
    39541 taaaccctcc tctctctttt gttgaaaccg ctttcttatg tgataaaaat atcattttta
    39601 ttatttgttg tcaaggaaaa aatcgaattt tttagatatt ttactacatt gcctctatga
    39661 ataatattat atagtagttt tattttaaaa taatatgcaa ccagtactaa ccaaatataa
    39721 aatagatgcc attaacgaat tttattcaag tttttcccat tcatactatc caagcaaaag
    39781 agatgatgtt atagtacaaa acaattcaaa ctattgtaaa attcctagca aaaaagagag
    39841 ccaaaactct cttttttatc ttcttttact ttttttgact ggcatgagtg taatgtctct
    39901 aacactaaag taagctagga tcaacatggc tattgctagg aatatttctg ttggtaattg
    39961 aaaaattttc agaaaagata gaaccaataa aatcaagagt gccactaaaa tacataccat
    40021 agcgacgata ttgactgtcc ctttaatgct ttctggtgtc gcaaatacat agagtaggag
    40081 cagtaaaatt cctaggacta aatagaccat ctttctctct ttctagctct tattcagctg
    40141 attttttctt cttgttagct ttctcacgct ctgctttgtt aaggatttgt ttacgcaaac
    40201 ggatagactc aggcgttact tccatgtact catcgtcgtt caagaactca agagactctt
    40261 caagtgtcaa gatacgaggc gtcttgataa cagctgtttg gtccttagta gctgaacgaa
    40321 cgttggtcat ttgttttgcc ttcgtgatgt taactgtcaa gtcattttca cgagagtttt
    40381 caccgatgat cattccttca taaacctcag tacctgggtt gacaaagatc gtaccacgtt
    40441 cttcgataga catgattgag taagttgtag ccttaccagc atcgatagaa acaagggcac
    40501 cacggtgacg tccaccaatt tcccctggaa tcaatggcaa gtattggtcg aaggtatggt
    40561 tcatgatacc gtaaccacga gtcattgaca agaactcagt tgagtatcca atcaaaccac
    40621 gcgctggaac aaggaagacc aaacgagttt gaccattacc agttgaaatc atatccaaca
    40681 tttcaccttt acgttcagaa aggctttgga taacagaccc ttggtattct tctggagtgt
    40741 cgatttgtac acgttcaaat ggttcacatt taacaccgtc gatttctttt acgataactt
    40801 ctggacgaga tacttgaagt tcatagccct cacgacgcat tgtttcgata aggattgaca
    40861 agtgcaattc tccacgtcct gaaacagtcc atttatctgg tgaatcagtt gggtcaacac
    40921 gaagggaaac gtctgtttgc aattctgcct gcaagcgttc ttccacctta cgagaagtta
    40981 cccatttacc ttctttacca gcaaatggtg agttgttgac caagaaagtc atttgaagag
    41041 ttggctcatc gatgtgtagg attggaagag cttctactgc atctgtcgga gtgatggttt
    41101 caccgacaaa gatgtcttcc atacctgaaa cggcaatcaa gtcacccgct ttggcttctt
    41161 ggatttcacg acgttccaaa ccaaagaaac cgaagagttt tgtaacacgg aagtttttag
    41221 ttgtaccgtc aagtttagaa agggtaactt ggtccccaac cttaactgta ccacggaaga
    41281 cacgaccgat accgatacgt ccaacgaagt cattgtagtc caaaagtgac acttggaact
    41341 gcaaaggctc atctgagtta tctactggag ctgggatatg gtcgataatc gtgtcaaaga
    41401 ttggtgccat agtcgcttct tggtcagctg gatcatctga caatgaagaa gttccgttga
    41461 tcgctgaagc ataaaccact gggaaatcaa gctggtcgtc atctgcacca agctcgatga
    41521 aaagttccaa gacttcatcc actacttctg ctggacgagc tgatggctta tcgattttgt
    41581 taacaaccac gattgggaca aggtcttgtt ccaaggcttt tttcaatacg aaacgagttt
    41641 gtggcatggt tccttcatag gcatctacga ccaagacaac accgtcaacc attttcatga
    41701 tacgctcaac ttctccacca aagtccgcgt gtcctggtgt gtccataatg ttgatacgag
    41761 ttccgttgta agcaacggca gtatttttag caaggatggt aatcccacgc tctttttcga
    41821 tatcgtttga gtccatagca cgctctgcca attcagtacg tgcatcaagc gtttctgatt
    41881 gtttcaataa ttcgtcaacc agggttgttt taccgtggtc aacgtgggcg ataatcgcaa
    41941 tgttacggat atcttctctt aattttgtca tgatttcctc tataatattc aaaatttatt
    42001 ttctaactga acgattatac cataatttca aataaataac ataactcaag caagtgtaaa
    42061 tgttttcact ccgcttttct tttcacgtca agccttttca aagcaagcga cttatgataa
    42121 gataggcaca gtatgcgttt agataattta ttagcccaag aaaaagttag ccgaaaggcc
    42181 atgaagcaag cactcctcag aggggaaatt ctagtcgatg gttgcccagc ccgatcccta
    42241 gctcaaaata tcgatacagg actacaagaa ctcctttttc aggatcgaat cattcaaggc
    42301 tatgaacaca cctatcttat gcttcataag cctgctggtg tcgttacagc caacaaagac
    42361 aaggaacttc cgaccgtcat ggacctgctt ccatctgaca tccagtctga caagctctat
    42421 gccgttggcc gactggaccg agatacaacg ggactcctcc tcttgaccga taacggtccc
    42481 ttgggctttc agctcctcca tccccaatat catgtcgata agacttacca agtccaggtt
    42541 aatgaacttc taacacctga ccatatccaa gcctttcaaa agggaattgt ctttttagat
    42601 ggtactgtct gtaaacccgc aaaactagag attctatctg caagtccctc cctcagtcaa
    42661 gcctctatca ccatttcaga aggaaaattt catcaaatca agaaaatgtt cctctcggtt
    42721 ggtgttaagg tgactagcct caaaagaatc caatttgggg acttcacatt gaacccagat
    42781 ttagcagaaa gtaactaccg ccctttgaac caaaaagagt tacaaatcat taaaaactat
    42841 ttagagatga gtcgataaaa caaaaaaagc tttaaaacta aagctttttt cttttattta
    42901 ccgaaaaatt aaggcgattg ctacaatcca gttaactaca gaaatcacaa ttcctaagat
    42961 attaagaatc ttttctattt tatagtctaa ttgtgactct ttttggtatg aaatagccaa
    43021 gaccaatcct atgataccca aaatcaagcc tacaattgga aataacaaac caagaataat
    43081 cgacaagata cccacaaaaa gtggattttt cttcttttct ttcatgttct aagaactctt
    43141 taaattttat acaaattaat tatactataa aacaatagct tcatcctatc attcgactaa
    43201 tttggaaata aggttagcta gtcttcactt tccctttcca agaatccaag ccataagaaa
    43261 ggatataaat ctcagaaaaa ccttgttttt tcaagtaaag agctgcattt gtaactcgtt
    43321 gcgcacgttg gttctcgtag agaaggacag gtttatcttt acgaagggct gcaagactag
    43381 ttttcaactg acttgaagga atattgcgtg caccaaggat atgttttctg tggaattctg
    43441 ctgggtcgcg caaatcaatc aattgacccg tacgaatcaa ggcttcaaac tcctcattgt
    43501 ccacaatttt agccgcacga cgaatacgaa gatagttaaa gcccatccac gccaacattg
    43561 ctagtataag tgcccacaaa atccaagtaa ccattagttc ttttctccat ttttctcaat
    43621 ataatccaat tctaccttgt gctctctgcg aagaactgct tctgcctcta gatagtctaa
    43681 tttatccatc aaccctgcat cgtaaatccg agatagttcc aacttcatca gttcaatatc
    43741 atataagcgt tttcccatgt aaacaataat accaaatcgt ttgaggaatt gctgcacatc
    43801 atagaatgtt ttcataagac tcattctagc aaaattttgt gtttttttca agaagagact
    43861 cacacaatgc tccttatttt cctatcttct ttggcgattc taaggcaagt gtggtacaat
    43921 aaaaacatga gaattcaaca attacattat attatcaaaa tcgtcgaaac tggctctatg
    43981 aatgaggcag ccaagcaact ctttatcact cagccaagtc tttccaatgc tgtgagagat
    44041 ttggaaaatg aaatgggcat tgagatcttt atccgcaatc ccaagggaat caccttgacc
    44101 cgtgatggga tggagtttct ctcttatgcc cgtcaggttg tcgagcaaac tcagcttctg
    44161 gaggaacgct ataaaaatcc tgtcgcccac cgcgaactct ttagcgtttc gtctcaacac
    44221 tatgcctttg tggtcaatgc ctttgtctct ttgctcaaga aaagcgatat ggagaaatac
    44281 gagcttttcc ttcgtgaaac tcggacttgg gagattatcg acgacgtcaa gaacttccgc
    44341 agtgaggtcg gggtcctctt cttaaacagt tacaaccgtg atgttttaac caagatgctg
    44401 gatgacaatc acctactagc ccaccatctc ttcacagcgc aaccgcatat ctttgtcagc
    44461 aagaccaacc ctctggcaaa gaaagacaag gtgaaactgt ctgatttgga gaatttccct
    44521 tacctcagct atgaccaagg gacgcacaac tccttctact tttcagaaga gattctttct
    44581 caagaacacc acaagaaatc cattgtggtc agtgaccgtg ccaccctctt taatctcttg
    44641 attggtttgg atggttatac cattgcgaca gggattttga acagcaacct aaacggagac
    44701 aatatcgttt ctatcccact ggatattgat gacccgattg agctggtcta tatccagcat
    44761 gagaaaacca gcctatctaa gatgggcgaa cgctttatcg actatctact agaagaagtt
    44821 cagtttgata gttgagaaat gataagaacc aatatgtagg ctagcaacaa cctgcacatt
    44881 ggttcttttt acttataatt aaaagtttcc cctgccaact tatcagctag cttgggaaag
    44941 agagtataaa acttatgggc taggttcaac aaaatcggga gattgagttc tcgtttattt
    45001 tttcctataa tcttgacaat ctttttagcc actgcatctg cctctaagag gaagcggtca
    45061 accgatttaa gataagttcc atctgggtca gcttggtcaa aaaatcctgt tcggattgga
    45121 cctggattga ctgttgtcac atagactcca tagggcataa gttcgagtcg cagagcattt
    45181 gaaaaaccaa tagccgcaaa cttggtcgct gagtaaagac tagacttgcc agtagctatt
    45241 agacctgcca tgctgacgat gttgatgata tgccctttgc tgctttcctt catacgagcc
    45301 gcaaggtgac gagacagatt catcagggca aaggtattga cctcaaacat ctggtgaata
    45361 tctttatcag caatctggtc aaatccctca aaaatcccgt aaccagcgtt gttaatcaag
    45421 acatcaatct tgccatagcg gagataaaga tcagttacca gagcttctag ggctgaatcg
    45481 tcggtaatat caatttcaat caattctgca tgggaataat ttccgtagag ttgggctaat
    45541 ttttccttat ttctaccaag caagatgagt tggtcattgg gcaggagttt gaccatttct
    45601 tgagctagac caccgctagc tccggtaatg agaatagtag gcatacttat cctttctgtg
    45661 actgctagat ttccacttct tccaagtctt tgaccacatg gacattttca aaaattgtgg
    45721 cagcgtcctt cttgagtttg cttatatctt ttgagaggaa acgggcactg atatggttga
    45781 gtaggaggcg tttggcacct gcttctaccg ctacttgtgc agcttgcata ttagttgagt
    45841 gaccatggtt acgagcaatt ttttcatcac ccttgccata agtggactca tgaactagga
    45901 catctgcatt gacagccaga cgcacactgg catccgtttt tcgagtgtct cctaaaatag
    45961 tgataatctt acctggacgt ggcgctgaga tatagtctgc tgccttgatt tcagttccgt
    46021 cttccaaaac aagatcctgg ccgtttttga ttttaccaaa aagcgggccg aacggaacac
    46081 cagcagcctt gagtttttca gcatccagcg tcccttctag atccttttgc atgacacgat
    46141 agccaacaca gaaaatagtg tggtccagct cctctgcata cacagtgaat ttatcggttt
    46201 caagaatttt acccagagaa tcttggtcaa actcatggaa atgaatgcgg tagggcagac
    46261 gagaacctga cacacgaagg ctggttaaga caaatgactt gattccttga ggtccgtaga
    46321 tttccaaatc tgtctgctct tcattggcct gaaaggcacg gctagaaagg aaacctggca
    46381 aaccaaaaat gtggtctcca tgcagatgag taataaagat tttgctgacc ttacgtggtc
    46441 gaattgtggt ttccagaatg cgattttgcg taccttctcc acagtcaaag agccaaactt
    46501 cgttaatctc gtccaaaagt ttcagggcga gacttgaaac gttgcgggct ttagagggct
    46561 gaccagcccc cgttcctaaa aattgaatat ccattcgata ctttctaatt aatcaatata
    46621 taacatggct gtgcggtttt ccgatcggaa atagcgtttg ccagaaaaag cagcagcttc
    46681 ttgcaataaa tcctcttggc tgtagccttt gagacgtttt cgaccatcag ccaatctttc
    46741 caaatcagtc aaagctgtga gactttctag gctgacaact tcctcgtcct tgacaggctt
    46801 catgtaaatc ttaccagact cttcaaagac taattgatgg gagaaaattt gcgcaatttc
    46861 aaagagcaag tcatccgaga ttttctcctc attttcagag aaaatccgac caaagccgtc
    46921 actctcataa caaaaaccaa aggatttacc agacagatta agccgaataa aaggcttatt
    46981 ttctagggtg aaacttggct cagtattgta aagattcagt tcctgactga gttctgcaaa
    47041 ataatccgtc gcagcctgag gacttttttt ctgatagagt tctgcaaagt aggcattaac
    47101 aacacttggc ggaggtgtaa taagtgttaa ctgctcctgc tctgttttac cagctagaag
    47161 ctgatccaga tagaccttgt ccagacttgt ataacctcca tactttagag ccaaagtttt
    47221 aatatcagtc ataaaattct tctaacctcc atttattttt ctcggaaatg tagcctgtaa
    47281 tcacttcgcc gtcttcctga taatcacgtt cttccagaat tgcaacactc tctaaatcat
    47341 gaatcttgta ggactttgaa aaaggcactc gcagggtaaa tgcttcaaaa atttccttaa
    47401 tcttatctag caataatgct tgcaagtttt cacgactgtc ctcagacttg gcagaaatga
    47461 gggtatatgg cgtttgggta ggcgtgaaat cctccaccaa atccgcttta ttataaagcg
    47521 tcaagtgagg aatatcttcc atgtccaggt ctttcatgat ggagagaacc gttttttcat
    47581 gctcctcgtg gtaaggattg ctagcatcga taacatgaac cagaaggtcc acatgcttgc
    47641 tttcttccaa ggttgacttg aaactggaca ccaactctgt cggcaaatct tggataaagc
    47701 caacagtatc tgtcaaagtt acttggagat tgcctcccag atgaatactc ttggttgtcg
    47761 catccagagt cgcaaagagc tcatctgctt catactgggt cttactggtc aagatgttca
    47821 tgatagttga tttcccagca ttagtataac caatcaaacc aatcttaaaa gtgctagact
    47881 ccaaacgttt ttctctgaca gtcgcacgat ttttctcaac caccttaagc tggcgctcga
    47941 tatccgtgat ttgattgcga acgctacgac ggttcagctc cagttggctt tcaccaggac
    48001 cacgggaacc aattccccct gcctgacggc tgagcataat cccctgacca accaagcgag
    48061 gcaagaggta tttgagttgg gctaggtgga cttggagctt cccttcatgg cttcgagccc
    48121 gcatggcaaa gatatccaaa atcaactgca tacggtcaat gaccttaaca ccgagaactt
    48181 cctctagatt gacattctgc cttggggtca gacggttgtt gacgatgaca gtagtgattt
    48241 cttctgcatc caccataagc gcaatctctt ccaacttacc agagccgacg aaggtcttgg
    48301 aatcatattt ttcacgtttt tgtctgtagc tatctacaac gactgcccct gccgttttcg
    48361 ctaaactagc caattcttcc atggagaggt caaaactgtc cataccctgc aattccacac
    48421 caatcagcag gactcgctcc tcttttttct ccgtttcaat catctaaaaa ctcctctatc
    48481 tggcttaaaa tgcggtcttg tacaccagat tctccaatct gataaaaggt gacctgcatg
    48541 cgattacgga accaggtcag ctgacgcttg gcaaaacgac gggtcgcctg tttaagactc
    48601 tcacgagctt cctccaaggt ctgctctcca cggaaataag gaaagagttc cttatagcca
    48661 attcctttag cagcctgtac attaggggaa tggtcaaaca gccacttggc ctcatccaaa
    48721 agcccagcct caaacatcaa atccactcgg tggttgatac gctcataaag ttgactacgt
    48781 tcatcatcca agcagataat cagcggttca tacaaaatct cttgattttc caaatcctga
    48841 ccaaaatggg caatttctaa ggcacgcata gcacgacgac gattaaactg gggaatctca
    48901 aggcctgctt gctccaccaa atgggctaat tcctcatctg aatatggctc caaactagct
    48961 cgataagcta aaatctcctc atgaggagtc tccccaccta ggtggtaacc ttctagcaag
    49021 ctctggatat aaagtccagt cccaccggcg ataatggcta gcttgccacg gctgtgaata
    49081 tcctcaatag tcatcttagc ttctgaaaca aaatcaaaag ccgagtaaga ctcagttatc
    49141 tctctaacat cgattaaatg atgaggaaca gctgcctgct cttctggact agccttggcc
    49201 gtcccaatat caagtcctcg atagacttgc tggctatctc cactaaccac ttcgccatta
    49261 aagcactttg caacttcaat agctagagcc gtctttccaa cagcagtcgg tccaacaatc
    49321 acaattattt ttgttttcat cttttttcct tgaaaaattc ccattttttc gttactatta
    49381 ttataacaca aaaaggtcag tcagaaaaat gtgacctctt gaggaggctg gctgattgag
    49441 aatataaagg aggaagactc atggctaaag gattcgctaa aggtcttgta acaggtgtcg
    49501 caggaactgt cgctgccgtt gcaggtgcag tatacgcatt taaaaagaaa gtaatcgaac
    49561 cagaagagca aaaagcagct ttcatcgaag aaaaccgtaa aaaagcagct cgtcgccgcg
    49621 tatcacgtta agaaacaaaa gaagttggga ttattctcaa cttctttttt ctattctttt
    49681 aaatagctag gtcaaacttc aactgtggct taacagggtc ataatccacc aactcaaaat
    49741 cttctgcttt gatatcaaag aaattagtcc catcaggaac atttaaaacc aagcgtggtt
    49801 ggcagtttga cggctcccga cggagcaatt cctgagcttg ttcaaattga ttatcataga
    49861 tatggaggtt gttgatgaag tagaagaact tcccaacctt ccagccaaaa tgtttagcaa
    49921 tcatcatctg caaagccaca tactgcatag cgttgatgtg gtgggccacc agcatatcat
    49981 tggagcgctg ggtcaaggtc gcatccagat agatttcccc atcaacacgc cgaacatcaa
    50041 acatggtctg aaaggcgcac gggagcagcc catctgtttc ttcgaaagct tggtaatccc
    50101 agagagaaat aatattgcgg cggttccaag gattggtttc caactgtttg agaagcttat
    50161 tgataatgtc gtgtttctta acaacggcac catagcgctc accaatggtt cccgtgtctc
    50221 caacttccca gtcattccag tagtgaacat tgtacttgtc attaagcact tctaagctat
    50281 ttgactggtc ttggtaaatc cagagaactt ctttgatggc ggatttgatt gcaatgggac
    50341 gcaaggttat gataggaaat tctcctttag ataagtcgta ctcggaaaag gcaccagtta
    50401 catacttgga attagcaaca gtcccatcct tgtacttagg acgagcctgc tctgagaaaa
    50461 caccttcctt tagaatgcgt tcaatattct ctttaaaaat cgtatctgct tttgtcattt
    50521 actctcacct cattcattgt cctaactagt atagcataaa aaataaaaga ggaacattac
    50581 taactctagg ttagcatttt cctctctcat tatcttattg caatacaagt gatgctgctc
    50641 cgataactcc agcgtcattt cctagagttg caagagctaa tttagtagat gtgcgtactt
    50701 gtgggaaagt attttcgtca tagacttttt gaacaccttg tagaaggaat tctcccgcag
    50761 ctgacacacc accaccgatg acgattgttg atgggtttag gattgaacca atgttagcac
    50821 aagcgattcc caagtaacgt gagaagttac ggtaaacaat caaagcaagg tcgtctcctt
    50881 cttttgcgag atcaaagaca gtcttagcag ttacttcttc tccgttatca atcaagcgtt
    50941 tcaaggctgc atcgccttcg tattcatcgg catagcgacg agtcaagttg acaattcctg
    51001 ttgcagaagc gactgtctca agacagcctt tcttaccgca agtacatgag attggctggt
    51061 caaagtcaac agtgatgtga cccaactcac ctgctgcacc agcaacaccg tgaagcaatt
    51121 tgccttctgc gacgataccg ccaccaacac cagtaccgag tgtcataaag acaacatctg
    51181 gttggttatc accagcaccc atccagcgct caccaagagc tgctacgttg gcatcattat
    51241 cgatgaaaaa tggaatgccc aaagcttttt caatcttttg tttgattggt tgaagggttt
    51301 tccagttcaa gttgtaggca ccgataacag tccctttgtc acggtcaacc acacctggtg
    51361 atcccattcc aatgccttgg aagtccgctg ctgccaatcc aagcaagtcc aaacgatgtt
    51421 gaatagactc aatcatatca tcaacgatat gacttccctc atccaaaatg ttggtcttga
    51481 ttgaccattt tccttggatt tctcctgctg ttgttaagat tgcaaatttg atagaagttc
    51541 caccaaggtc aatcccaata atcttttgac tcattatatt ctcctttttc attgtgtagt
    51601 aattgaaaat gcttacagta ctagtatatc aaaatccatt cacttatgca aaggtttgcg
    51661 taaatgaatt ataaggaatt ttttcgccta ccagtatctg ttaaccatct aaatgatcaa
    51721 tggcatattg agctgcatca tttgaaaatt tatcaaaatc agaagttaat tgtctataca
    51781 tacgtttttt tgacatgtgg aataacgaat tataactttt tgcctttcct aaagcagcag
    51841 aatattcact attgctatca ttactagaag aagctgtact tgcttgacct tccttccaaa
    51901 ctccgtcagc gccaacataa taacgtccac catcaaccca ttcattgaca gccattttac
    51961 catccgattt tagatagtaa tttccttgcc atgtactata agcataagaa ccatctgatg
    52021 tcaaataata ccaagcttga taggtggcat cataaaccca ttcaccttta gccattttac
    52081 catctgattt caaatagtag tttccttgcc atgcattgcg agcatatgaa ccatctgatt
    52141 tcaagtaata ccatgcttgg taagaagaat cataaaccca ctcaccttgt gccattttac
    52201 cgtttgattt aaggtaataa gctccttgcc atgcattttt tgcataagaa ccatctgatt
    52261 tcaaataata ccaagcttga taagaagagt cataaatcca ttcactctgt gccattttgc
    52321 catcagcttt caggtaatag tttccctgcc atgcattttt cactagattt ccatttccat
    52381 caaaatagta ccaagaaccg tcctgcttaa cccaaccact tgctgtggat gaagttgtat
    52441 cagtttgagt tgtagccgct tgttttgctt taaaagcacc cttaggagca tttttcaatt
    52501 cgcaagccac accatcatga tcgcggtcta acttggcaga ataaccaggt tctccctcat
    52561 gaagatccga atatccatta gcccaagctt ccttacagct cgaaaaatgg atgttttctt
    52621 ccgccaaaac tggttgtgaa aacaaggcta aaattggcaa cgtcaccaga ctcattttta
    52681 aaaatagacg tttattcatt tctttctccc ataattatga tatcgatttc aatattattt
    52741 tatcaaactt atttcagcaa ttcaaggaaa cttctggtct tttctacaaa ctcctttggt
    52801 tttgccttat tcaagacatg agggccatca ggaatgatct gaaactgcga atctgttaac
    52861 agtctatgga gagctttcat agaactaaga ttcggtttat ctttgctgcc acaaattagt
    52921 aaggttggat aggagcaagt ccctgctata tccgttaaat caagtgtctt caattcctca
    52981 gaaactccga ccataagagt cttgtctgct ccctgttttt caaatactct tttgggaagt
    53041 agtttaaaaa tcagcaactg aagataaaat aggatattcc ctgctaattt aagcgggcat
    53101 cctgacagaa tcaaagctcg aagatttggt aaatcgtaac tggaaagttc tagtgtcagg
    53161 gcagcaccta aggacaatcc aatcaaaaca aaaggttctg tctcttgagc taggtgctga
    53221 taaactcgct ctttagcttg ttgatagtta ctaactccag aaggaaataa ctcgatagcc
    53281 tcagaaggat aatctgtcag tagattccga acttctttcc aagactctgc tgactgccct
    53341 aacccatgca aaaatatcaa tttcatctag ttctcctcaa ggcttagttc atacaagcct
    53401 ctcactgcat tacagccgta aatagcttct gcttgggtta aatctgccaa ggtcaagact
    53461 ttctcttcta cctgtcctgt ttctagcaaa tactgacggt aaattcctgg taagattcca
    53521 agtcggatag gcggtgtgta gagttttcca gcgattttca gaaccaaatt tcctatagag
    53581 gtttcaagca gttctcctga cttattgtgg taaatcttct cttgttctcc taggctcaaa
    53641 tgcggtcggt gagtggtttt aaagtaggta aaggattgat tcaaagcagc ttcctgaagg
    53701 cagacttggg cctgacaaaa gcttgtactg agaggggtta atacttgacg attgacttct
    53761 atctctccag atttgctaag gctgattcgc aagcggtaat ctcgattagc ttcacaatcc
    53821 tgacactctt cctcaatctt gtgtcccaag tcttctgcat caaaaggaaa agcaaaataa
    53881 cgactagctt ttctcagtct ttccagatgt tgatcttcaa acagcaggtt cttctggctg
    53941 atttcccctg tcgtaatcag ttggaagcga gcttgtttac gataaagaac tgctgccttt
    54001 tgatgaacct ctcggtattc agattcccat gtgctatccc aagtaatccc tccgccaact
    54061 ccataaatgg cttgaccttt gtgaagttga atggtacgaa tggccacatt aaaaatccgt
    54121 cgtccatttg gaagcaagag accaatcgtt ccacagtaga ctccacgcgg ttgaggctcc
    54181 aagtccttga taatctccat tgtcgcaatt ttcggtgcac ccgttatgga accacaagga
    54241 aagagtgagc ggaagatttc aacaaggtcc acatcctctc gcaactgact cttgatggtc
    54301 gaagtcatct gccaaacagt tgaatactgc tctacctgac acagacgctc cacgtgctcg
    54361 ctcccaactt cagaaatacg gttcatatca ttgcgcaaga ggtccacaat catcatattt
    54421 tcagagcgat ttttgggatc ctgttccaac caactggcct gttcaagatc ttcttggtca
    54481 gttaccccac gctgagtcgt ccccttcatt ggtcgtgttg tcaactcgcg atcattttgc
    54541 tcaaaaaaga gctctgggct catggaaatc actgccatct cgtcatgttc cacataggca
    54601 ttgtagcccg cctcctgctc taccaccata cgattgtaga tggcaaaagg attggcactt
    54661 aacttttgct tgagttggac ggtgtagttg acctgatagg tgtctccctg cctcaagtga
    54721 tggtgtatct gggcaatggc cttttcatag tctgctgcag acgtcacttc ctgccaattt
    54781 gagggcaaat caatatcctc ataagtcaga ggaatagggg aagtttctac gctatcatga
    54841 acagtaaagt aaagcaggta ctctcccagt aggggatcct tgtgaactgc taatttttcc
    54901 tcaaaagcag gtgcagcctc gtagctgaca taccccacca cataataacc ttgctcttgg
    54961 tagctttcca cttgtgccag caaatctgcc acttcttcta catttctcgt tttcaactct
    55021 ttaataggct gggcaaaggt atatctctcc cctaaagtcc taaaatcaat cactgttttt
    55081 ctatgcatac cttaagtata gcataaaaag gcagatacag acaaagctga tctacctttt
    55141 tacgatttta ttcattctat gcttgtggtg cagtaaatag atcaccagag aaaccgtctg
    55201 tgtttttaag gagagcttta aagactttcg atttcaagac aactgtattt cggtatttgt
    55261 ctttaatact actatcgttt agttccgtta aatctttagt aacagcctca tcaaacatag
    55321 tcttcaactg ttcataggtt gaaatttgag tgccattaat ttcaattggt gcaaaacctt
    55381 ttttagattt tgtaagaact tccccatacc attgcttctt ccaatcttca aggtttgaaa
    55441 attggttatt agaaactttc ttaataatga aatcatcacc taatagaccg ttattttctt
    55501 tattggctgc accttgatgt ttgcttgaaa catagtcaat gaacccatgt tcatatccat
    55561 agtaacccca catacggaag gcgttatgtt tgaaggatag agaaccaggg gcaccttgac
    55621 tcgtattacc gccataaata ccagccatca tattaacatt gacatatgcc gtaccaaagt
    55681 cctctgggtg gaagacctta ttacctggat ttccgtgaat ggtcatgaaa ttattattta
    55741 ccaagtcatc gatggtttca aggttagttg ttttctcagc gtctatcaaa tcacgcactt
    55801 tgtcccattg gtgaggacca cttagtttat ttctgtccat tggtcgacgt gtttcgcgat
    55861 caattttctt gaaccactta ctattgtcac ctttaacctt aggaagaaca gcctcagctt
    55921 ctgcataatc gagcatcatc atagcttcat tgtagttctt catgtaatgg tcgatttggt
    55981 cacgtgtttg aagtttggta ggatctggat tataccattg gtttccatca tttgaacgtt
    56041 caaatgccat atttaatcca agtgcgccat attcaccttg atgtccatgt tctgctggag
    56101 tttgtaacat accttgagca aatgcttcaa gatctgtacc ctgtcgatgt ctatgacctc
    56161 ccagatatgc cattcggtca tttacgtggg tagtctcatg tgtaaaggca gatgtgccat
    56221 attcacttat taaatccgac ataacaaaat atacagcatc cataggctgt ggatcagcaa
    56281 agatgtaagc atacgctcca tacccatact tataatcatg atacttatca atacgtccaa
    56341 agaattcacg aataggtgca taatccggtt tatcttttcg atgaccaaat ctatcaggcc
    56401 aaccaccggg tgcaccatga ttatcccata caggagttgg aactacattt tgactcttaa
    56461 gaagtttatc gcggacatta tcagtggcaa ggcgtgacca aaaatctaag taattaactt
    56521 gctctttagc acgtttattg atttcactct tgaacgattc acgtttttct tctgtatctt
    56581 taccatactt ttcaaacgaa ctaaatgaga tagtattata tgttgaaatc ataaataaat
    56641 gtgcatcttt caagttcaga agcgataaaa tcatgcgtcc atgttgtccg ttattaagtc
    56701 cttcatatag acgatatttt ttattagcaa atgcagggtt agttgacggt tgttcaacta
    56761 cataagcatt attttcaata gctttcttaa accaaacatt tatgtctgtt tcatttgtga
    56821 atagtttcat attgtaggtc aagaagtcat gtaagtttcc agaaagagta tttttcgcca
    56881 ccacttcacg gaaggactcc tgtgtacgac ttcccttaat atagtcctct tttgaaccaa
    56941 tttctattaa tcgatctaaa acacttacat tcttaccata aaaatctggt ttgaatagca
    57001 ttaattcttt aatattgaag ttatcaaatt tcacaccgta ataacgattt aggtatgtta
    57061 atcctaacag gacagcagct ttgttatctt caattttctt aatcaaggca cgttttgcag
    57121 cttcatctgt attcagttga tgatcttcat tttcaactaa ttttgtcaca aatgtattaa
    57181 gatgatcttt tacttcttta aagctttctt ctaagtaaag attcttaatt gcattaactc
    57241 tgttatcccc agttcttcct aatcgttgat aaattggatc agattgtaat tcaattggac
    57301 ttaaaatacc ttcaatagca ctaattaaat ctgcacgatc tttaacaacc atatttggtg
    57361 tatagacgac ttcaccaagc tctgcgacac tgtattcttt tacttgctta acttgagagt
    57421 ctttaggaga aatcgtaaag atatcttttg tcttatctgc gtaatgaacc ataatatggt
    57481 cagcatctgt aaggtctgta ataaagtcat tacctttcat tgcagtcaca gacaatactt
    57541 ctttattcat taatggacta tcagttgtaa gcttgttccc ttgattcaca atccattctt
    57601 tgttgtagaa cggttggagt ttttcaacat tacgataaac aagctcacga tttgcattat
    57661 aatcttgaat tgttttgtat tcttcatcac gtaatatacg gcgattcaac ttatcaacca
    57721 aatgctcagt tacttcaaat gtatcagcag tgatacccat atccttaatt ttcttatcag
    57781 cttctacctg tgaaatttct ttaattttag acgattgttt atgggtttta tctccagaac
    57841 tcacaccgat aactgttgca ttattaggtt taatccaatt gcttacaaat tcatcatcca
    57901 tatcattaga accaaagaaa atatcaccac gcttaacatt cactaagctg atattgttat
    57961 caatggttcc ccaaggccag tctttaccaa ttaaaccgcc tacatcacct ctagcaacat
    58021 caatagtacc tttggctaca gaatttctta cattagacca agcaccaaca tctcttggat
    58081 taaaatcatg agctaaatgt cctactatag cacctgcacg agtatttaaa cctttaagtt
    58141 caacatctgc ataagcttta tttaaattgc ctcgataaat ctcagatgca atcccagcca
    58201 agttccaccc tttatcacca acagattgaa cttttccgat aaaagcaaca ttagtcataa
    58261 tacctgcatc atctaattta tccaaaatac ccgcaacatt gttattacca acgatagtac
    58321 ccgttacttt aatattttca acagttgcat ttttcactgt ttgagctaat gaagctaatt
    58381 gatttgccca aggcatatta atattaacgt taattaaatt aatatttttg atagaacccc
    58441 cttcaactct atcaaataat ggacgagcag tgttatgaat ggagaaatgc ttaccatcaa
    58501 cacttgttaa gtgacctgta aatttacctg ttacatatga tttacttggt gtaggtacat
    58561 ttgttgcatt taaatccgat cctaatttaa actcaccgtt aggatttttc tgcatagcat
    58621 ctactaaatc tttgaagtta tagtaaacgt tattttgcga tgctttgggt ttctctatgt
    58681 aataagtgta tgtttgactc aaactattat ttgaatcacg ttggattaaa tcaggagctg
    58741 aagcagtaac tttaaataag gatgtctcct cctcagttac ttcctctata ttagtaatgg
    58801 caagccttgt tactttatta tgattagtgg taatttttag ataatatgac gttagatttt
    58861 ctggaacagt ttctagaagg ctactatctg tttcatttcc attctcatcc actttcatca
    58921 atcttgtttc tttaatatct ttaatctcaa cttttttaag gtctaactga acttctttat
    58981 cttctaatat ttcagtttct tcaccgttac ctcgatcata gaccatggtt gtggatagtg
    59041 tataaccttg ataatatttc aagttgtcta aagtagcttg taagttattt tcttctaccg
    59101 ttacttcttt aacaactgtt ccagtattat cttttagagc tactttaatc gatttaattt
    59161 ctactccagc tggtttagtc aatgtataac tagctgtcgc actcttcttc aagacatctt
    59221 tatctgtttt agcccattcc aaggttggtt tctctaactc ttttgtgcca ttcttaataa
    59281 ttttgtcttg aggtttttca atcactgttt ctgtgatagt aggagcgtca cttgtttttt
    59341 ctccgcgaat tgttttatag gtttcagtaa tttgtttctt atcgtttaca ccttcttgag
    59401 ttacttgtct tgttccgcgt tttaaagtgt catcttcttg ttcttttgtt tcaaaaggaa
    59461 tgatttcttc tcttgtctca accgttgtcc cttcaattgg ttttgtacca cggattacct
    59521 gttgatttac aggctccttg gtgacttccg tactggttga aagaacttgg tcagttttaa
    59581 cccctcctat tgttttatag gttgtttttg taacttgact tcctttttca ccatttcgta
    59641 ggacagtttc ttcgtccgtg tacttggttg ggtcctcagt cgtttcagtt ttatagtcaa
    59701 gttctgtagt tgattcttca acgagtgttc cttcagtcac cttatactca ggtaattgtt
    59761 ctggaacaag agcctcaccc acgtaatctt cttcttgcgt ccccttagct gttttagtct
    59821 cctcttttgg ttctacagtt tcttcagcct tggtatctgg agttgactct tcttgtttcg
    59881 gtgtctcttc cgctccccta tcttctttag gattgtcttc ttgtgatgat tcttttggtg
    59941 tacttggttg ctcagcttgt gtaggttgca cgggttgttc tgggactttt gcttgttcta
    60001 ctggtggttc aacttttgat tcctcagctg gtttgtctga tggttgactt tctggcttaa
    60061 ctgctacttt ttcctctgat tttgactcaa cttctccacc tacttcttca actggagctg
    60121 gttctgctga atcttctttc ccctcttcta ctttaggaag ggtgtcgtca gtaggtttta
    60181 cctccgattt tggttcttcc tttggacttt cttctgttct aggtgcttct tcttttggag
    60241 tttcctctgt ctctactact tggttttctg tcctagcttg ctcctgattt gttgttgatt
    60301 gaggagtctc aacttcgact acagtcacct ctccaggttt tgctgaggtt tcttctaaaa
    60361 cagtgtccaa gccaagcgtt ttgaggatgt cacctgatag ataaccaaca tagcgatagc
    60421 catccatttc aacaacaccc tctcgactag ccagcgctaa ggtcgcaact gggtctacag
    60481 cccctgcact aggaagaact accaatccca tagctccaac tagaaagacg ctagcaattt
    60541 tctttctctt gtagattaaa agcaagctcc caacagtcag caaaccaaaa gctgtcaaaa
    60601 cagatgcttc tgtccctgtt tgaggcaact gatctttttg atacaccaaa ccatatacaa
    60661 cttcattcct gtcaggcttt cctgtctgaa ttaaatcttt agcttcttgt gaaataatct
    60721 ctttatttac atagtgatag gtagctgcgt ccactacaga aggagccatc aaaaggcttc
    60781 caagaaatac agagcctaca actcccttaa tcttacgaat tgaaaaacgg tcttttttaa
    60841 acactttcat ctcctttatt cattctcaag actttctaat agcatcttgc ggatagtgcg
    60901 cacgcgcacc tccgattaat tttggacgac tagccagtgc cgttacatgg gcatgaccaa
    60961 tctctctcaa aatagggcga atcggaacct gaacatgctt gacatgcatg ccaattgcag
    61021 tgtctccgat atccaatcca gcatgagcct tgataaattc aacctcaact ggatcctgca
    61081 taaacttaaa ggctgccaac tgccccgaac ctcctgcatg aagagtagga tggacactga
    61141 caatttccag atcaaactgc tctgccacct gacgttcaac aacgagagcc cgattgacat
    61201 gctcacaacc ttgaactgct aaatggatac ctctactacc tagaataccc aagatagtct
    61261 ccactatcag ctcaccaatc tcttgactgg attctttccc aatctgacca cctagcacct
    61321 cactagaaga tagacctaaa acaaaaagga ccccctgctt caaattggtc ttttctaaaa
    61381 catcttccac tacctgacgt gtttctcttt gaatctgtgt ctcgttcatc tctgttacct
    61441 ctgttgtcac tcttctatca taccgttttt tcttgttttt agcaagatag acaacctata
    61501 aagtctgccc aattacgcat aaaactccca gaattgactg ggagttagct agtttctatt
    61561 ctatttatat atatttcaac tttcgttcct ttttggggtc tagaatcaat cttcatctgg
    61621 taattggctc caaaatgaag tttgagccgt tgatcgacat tttgaagacc aactccccca
    61681 cgtttgagtt gactttgact actatcacca gcatcttgga agccaacgcc atcatcctca
    61741 atacggatga ccaatcccga atcctgtttc tggacagaaa gtttaatatg gccctgacct
    61801 tccttttcct taatgccatg gtaaagagca ttttctacaa ggggttgtag gaccagcttg
    61861 ggtaagacta aattatcaaa ggcaacattt tcattaattt cgtattccag cttatctcca
    61921 tagcgttgtt tctggataaa gagatactgg cggacatgat tgatttcgtc agagagacaa
    61981 atcaagtcct tgccttgatt gagcgccaag cggaaatagg ttgccaagga cttggtcacc
    62041 tgcaccactc gctgactatc atgaaattca gccatccaga tgatggtgtc caaagtgtta
    62101 tagaggaaat gtggattaat ctggctcgaa agggcttgaa gttggtactg acgggtcgtt
    62161 tcttcctggc tacgaatagc taccatcaac tgatcaatct gatccaacat agcattaaat
    62221 tggcgagtta cttctctcag ttcataggca ccaacttcct tggcacgaag attttgagca
    62281 ccagaagcaa tttccaacat ggtttctctc aaatccttca aaggagcaat ccagcgttta
    62341 agactgaacc acactaagca gagacaaaca agaagagatg tgacactggc cccaagcaag
    62401 gtccacaaga gctgactccg aacctggtct aacttttcca atgatgacac gccaagtacc
    62461 gtccaatcag ttcctgcaat cttctcttga ctgacgtagg atttgtgacc aggagtataa
    62521 ccctgacctg tctcgatgta gggtttcata gcctccattt tgctagacga actataaact
    62581 gtgtgttgag gatggtagac aaattcatgg ttttcattga taatgaaggc aaagccctgc
    62641 tgccccaact ggagttgatt gagataggct tccagagttt cataagaaat atccaaacga
    62701 agcacaccaa gattggctcc ctttgcatca acaagttctt gagtgacaga aatgacccac
    62761 tgactatctg atttacgagc tggagtcaaa acaggcatag ctccctgatg aatagccttt
    62821 tggtaccaat cctcagccat catatcagag gaagttttca tctgcacact gtcatctgta
    62881 gaaatgacct gaccagattt ggtcaccagc acaacagttt tcaagtcctt atctgacttc
    62941 aagatggtca aaaacaaatc tcggattccc tcgaccttgt cttgactggg attctcagca
    63001 taggccagaa catccgtctg ctgggtcaaa ccagtcgagg tggtttctag ttttttgata
    63061 taagactgaa taaagtggct agtctggctg atggtcgttt ggctgttgcc ctcaatggtg
    63121 gcctcaatgg ctgaagaact tgattgatag tagaaagttc caaccagagc taggagaatg
    63181 agaaagacca gaaagatgga aataaccatt ctaactaaaa gagaagaacg cttcatcggt
    63241 cttctccctt cttaaactga cgaggtgtca cacctgcaat ctgcttaaaa cgttgggtaa
    63301 aatagttcat atcttcaaaa ccaaccttct ctgcgatctc ataaatcttc agatctgtag
    63361 ttaaaagcaa gagcttggct tgtttaacac gttctctcac cagataatcc tgaaaaggca
    63421 agcccaactc tttcttaatc aaggaactca gataggtcgg actaaaacct aagtcactgg
    63481 ctaaagactt taaactaaat tggctatcag ccagatgaga ctggattttc tgggccatgt
    63541 ttccttcaaa cctattagtc aataaatctt gtaactgctc ttctttctct tccttgtcta
    63601 gtttttgttt gattttcccc aacatttcct caatatcctg acgagaaaag ggtttgagca
    63661 ggtagtcgtc cacacctagt ttgacagcag acaaggcata atcaaaatca tcgtaacctg
    63721 ttaaaaagac caaatgaacc tgaggatagg tttctcgtac cagactggcc aactggatgc
    63781 catttagatg aggcatgttg atatcggtta aaatgatatc tggcacctgc ttttggatca
    63841 attcccaagc ctgccttcca ttttcagcct gaccgatgat ttccatatcg taggctgcta
    63901 cattgaccag tttagtcaaa ccttgtctta ccagatattc atcttctacg attaagattg
    63961 tgtaggtcat gctctgctcc tttaccactt actagtatca gtatagcaaa attctcctct
    64021 aactgcttag gaaagacctc ttatactcaa taaaaatcaa aaagtaaact aggaagatag
    64081 ccacaggttt ctcaaagtat agctttgagg ttgtaaataa aactgacgaa gtcagatcaa
    64141 agtatagctt tgaggttgta
//
LOCUS       DAVBCA010000004        51811 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.004, whole genome shotgun sequence.
ACCESSION   DAVBCA010000004 DAVBCA010000000
VERSION     DAVBCA010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 51811)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51811)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51811
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.004"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(1..210)
                     /locus_tag="VQU19_000211"
                     /pseudo
     CDS             complement(1..210)
                     /locus_tag="VQU19_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            196..681
                     /locus_tag="VQU19_000212"
     CDS             196..681
                     /locus_tag="VQU19_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HET2479535.1"
                     /translation="MAPTDKEDLIRTLELAPHVEGGYFRQTKKASDTINLAGKGRALY
                     TSIYFLLEETNPSHFHRLTADEIWYFHAGSPLTVHMITADGHYEAVTLGLDISKGQQL
                     HYCVPKGTIWGSTVDKDYALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTR
                     Y"
     gene            765..1472
                     /locus_tag="VQU19_000213"
     CDS             765..1472
                     /locus_tag="VQU19_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2479536.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            1473..2804
                     /locus_tag="VQU19_000214"
     CDS             1473..2804
                     /locus_tag="VQU19_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HET2479537.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGQGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSALKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            2971..3846
                     /locus_tag="VQU19_000215"
     CDS             2971..3846
                     /locus_tag="VQU19_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-binding protein"
                     /protein_id="HET2479538.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            3964..4827
                     /gene="pstC"
                     /locus_tag="VQU19_000216"
     CDS             3964..4827
                     /gene="pstC"
                     /locus_tag="VQU19_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HET2479539.1"
                     /translation="MTKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRTFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            4820..5635
                     /gene="pstA"
                     /locus_tag="VQU19_000217"
     CDS             4820..5635
                     /gene="pstA"
                     /locus_tag="VQU19_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HET2479540.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            5637..6389
                     /gene="pstB"
                     /locus_tag="VQU19_000218"
     CDS             5637..6389
                     /gene="pstB"
                     /locus_tag="VQU19_000218"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET2479541.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDVLLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            6404..7054
                     /gene="phoU"
                     /locus_tag="VQU19_000219"
     CDS             6404..7054
                     /gene="phoU"
                     /locus_tag="VQU19_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HET2479542.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            7122..7547
                     /locus_tag="VQU19_000220"
     CDS             7122..7547
                     /locus_tag="VQU19_000220"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2479543.1"
                     /translation="MNNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMMGCLAYNLYLFLKQLAGDEVKSLTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYRARGQGKTCLTE"
     gene            complement(7727..8104)
                     /locus_tag="VQU19_000221"
                     /pseudo
     CDS             complement(7727..8104)
                     /locus_tag="VQU19_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809823.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            8316..9332
                     /locus_tag="VQU19_000222"
     CDS             8316..9332
                     /locus_tag="VQU19_000222"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HET2479544.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     YHTNKHYFKDVVLDENIIAYTDLAETLKDVDAILFVVPTKVTRLVAQQVAQTLDHKAI
                     IMHASKGLEPDSHKRLSTILEEEIPEQLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            9354..10253
                     /gene="galU"
                     /locus_tag="VQU19_000223"
     CDS             9354..10253
                     /gene="galU"
                     /locus_tag="VQU19_000223"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HET2479545.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDKTTDMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYERTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FQILENQAPGAGNEIQLTDAIDTLNKTQRVFAREFNGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(10325..11002)
                     /locus_tag="VQU19_000224"
     CDS             complement(10325..11002)
                     /locus_tag="VQU19_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HET2479546.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(10986..11525)
                     /locus_tag="VQU19_000225"
     CDS             complement(10986..11525)
                     /locus_tag="VQU19_000225"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HET2479547.1"
                     /translation="MKSELRKQVLHEMKAISQEQKQAIDQALTERILQHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLTPKTYPKGRMDFVVYDPQQLVKTSFALLEPQ
                     GDLEVVDASQIDLIHVPGLAFTTDGYRIGYGGGYYDRYLEHFSGRALSTIYPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            complement(11537..12667)
                     /locus_tag="VQU19_000226"
     CDS             complement(11537..12667)
                     /locus_tag="VQU19_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HET2479548.1"
                     /translation="MLDLIQTRRALHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFTSQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPNQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            complement(12735..13433)
                     /gene="dapD"
                     /locus_tag="VQU19_000227"
     CDS             complement(12735..13433)
                     /gene="dapD"
                     /locus_tag="VQU19_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HET2479549.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVCVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            complement(13663..14574)
                     /locus_tag="VQU19_000228"
     CDS             complement(13663..14574)
                     /locus_tag="VQU19_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HET2479550.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCLEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVSVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            complement(14639..17104)
                     /locus_tag="VQU19_000229"
     CDS             complement(14639..17104)
                     /locus_tag="VQU19_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HET2479551.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGVGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            17246..18502
                     /locus_tag="VQU19_000230"
     CDS             17246..18502
                     /locus_tag="VQU19_000230"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HET2479552.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            complement(18580..20643)
                     /locus_tag="VQU19_000231"
     CDS             complement(18580..20643)
                     /locus_tag="VQU19_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HET2479553.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWFSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(20645..20923)
                     /locus_tag="VQU19_000232"
     CDS             complement(20645..20923)
                     /locus_tag="VQU19_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2479554.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            21068..21916
                     /locus_tag="VQU19_000233"
     CDS             21068..21916
                     /locus_tag="VQU19_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HET2479555.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            22538..23110
                     /locus_tag="VQU19_000234"
     CDS             22538..23110
                     /locus_tag="VQU19_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2479556.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     FAINLLSPGTYLAQLWDKNDAIPNNGRINF"
     gene            complement(24154..26412)
                     /locus_tag="VQU19_000235"
     CDS             complement(24154..26412)
                     /locus_tag="VQU19_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan phosphorylase"
                     /protein_id="HET2479557.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIDLDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINPNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(26438..27955)
                     /gene="malQ"
                     /locus_tag="VQU19_000236"
     CDS             complement(26438..27955)
                     /gene="malQ"
                     /locus_tag="VQU19_000236"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HET2479558.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLEASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEYFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            28505..29776
                     /locus_tag="VQU19_000237"
     CDS             28505..29776
                     /locus_tag="VQU19_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET2479559.1"
                     /translation="MSSKFMKSTAVLGTATLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIVGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            29887..31179
                     /locus_tag="VQU19_000238"
     CDS             29887..31179
                     /locus_tag="VQU19_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2479560.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGNKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            31181..32023
                     /locus_tag="VQU19_000239"
     CDS             31181..32023
                     /locus_tag="VQU19_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2479561.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            32284..33084
                     /locus_tag="VQU19_000240"
     CDS             32284..33084
                     /locus_tag="VQU19_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HET2479562.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTASQAPSVVIG
                     PSQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRIYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            33094..34080
                     /locus_tag="VQU19_000241"
     CDS             33094..34080
                     /locus_tag="VQU19_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET2479563.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            34216..34296
                     /locus_tag="VQU19_000242"
                     /pseudo
     CDS             34216..34296
                     /locus_tag="VQU19_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(34416..35357)
                     /locus_tag="VQU19_000243"
     CDS             complement(34416..35357)
                     /locus_tag="VQU19_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HET2479564.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(35335..37098)
                     /gene="aspS"
                     /locus_tag="VQU19_000244"
     CDS             complement(35335..37098)
                     /gene="aspS"
                     /locus_tag="VQU19_000244"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HET2479565.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEKEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVVNATLGTLRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSTEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
     gene            complement(37334..37414)
                     /locus_tag="VQU19_000245"
                     /pseudo
     CDS             complement(37334..37414)
                     /locus_tag="VQU19_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(37405..38694)
                     /locus_tag="VQU19_000246"
     CDS             complement(37405..38694)
                     /locus_tag="VQU19_000246"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HET2479566.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIAMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQAHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVTLPIENALDVYIA
                     VLGEGANIKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFAAKTLITLGESEVES
                     GQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            complement(38772..40019)
                     /locus_tag="VQU19_000247"
     CDS             complement(38772..40019)
                     /locus_tag="VQU19_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HET2479567.1"
                     /translation="MKLLFRNPAYRILTLSRFFNAFGVSIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTLFTVFAGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDIISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVSVIISSLTGNDYFGKQSLPRLMMWETVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFLGLLFTLSIPVGTACFSLVAVWNIQLT
                     WMLFVGLSLLAIFLTILNLKNDI"
     gene            complement(40210..41060)
                     /gene="rgg"
                     /locus_tag="VQU19_000248"
                     /pseudo
     CDS             complement(40210..41060)
                     /gene="rgg"
                     /locus_tag="VQU19_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398326.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes.; frameshifted;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
     gene            41184..41525
                     /locus_tag="VQU19_000249"
     CDS             41184..41525
                     /locus_tag="VQU19_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HET2479568.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            41583..41663
                     /locus_tag="VQU19_000250"
                     /pseudo
     CDS             41583..41663
                     /locus_tag="VQU19_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(41869..43572)
                     /gene="ilvD"
                     /locus_tag="VQU19_000251"
     CDS             complement(41869..43572)
                     /gene="ilvD"
                     /locus_tag="VQU19_000251"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HET2479569.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETSIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(43805..44737)
                     /locus_tag="VQU19_000252"
     CDS             complement(43805..44737)
                     /locus_tag="VQU19_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HET2479570.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSDSDIVVLEADLSSSMATNNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSALCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(44734..45591)
                     /locus_tag="VQU19_000253"
     CDS             complement(44734..45591)
                     /locus_tag="VQU19_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HET2479571.1"
                     /translation="MILSKNREDGLRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEEKQMLTSVVER
                     LSQELEETE"
     gene            complement(45595..46941)
                     /locus_tag="VQU19_000254"
     CDS             complement(45595..46941)
                     /locus_tag="VQU19_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET2479572.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATAMIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFVGGLVSMVIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSATEE"
     gene            complement(46954..47238)
                     /locus_tag="VQU19_000255"
     CDS             complement(46954..47238)
                     /locus_tag="VQU19_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET2479573.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            complement(47242..49272)
                     /locus_tag="VQU19_000256"
     CDS             complement(47242..49272)
                     /locus_tag="VQU19_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HET2479574.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NSHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLIDQVVKDYYEKLQLVPIVNQLKVYLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKWYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            49464..50471
                     /locus_tag="VQU19_000257"
     CDS             49464..50471
                     /locus_tag="VQU19_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HET2479575.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKQISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            50474..50674
                     /locus_tag="VQU19_000258"
     CDS             50474..50674
                     /locus_tag="VQU19_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET2479576.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            50826..51008
                     /gene="rpmF"
                     /locus_tag="VQU19_000259"
     CDS             50826..51008
                     /gene="rpmF"
                     /locus_tag="VQU19_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HET2479577.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKITKAASAE"
     gene            51024..51173
                     /gene="rpmG"
                     /locus_tag="VQU19_000260"
     CDS             51024..51173
                     /gene="rpmG"
                     /locus_tag="VQU19_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET2479578.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(51665..>51811)
                     /locus_tag="VQU19_000261"
     CDS             complement(51665..>51811)
                     /locus_tag="VQU19_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET2479579.1"
                     /translation="YLNESGSMATGWVTVSGKWYYTYNSGDLLVNTTTPDGYRVNANG
                     EWVG"
BASE COUNT        15910 a        11114 c         9578 g        15209 t
ORIGIN      
        1 aacaattctc ccttgacttg tgacaatcgc ttgagccttc atagcgtggc atttttttac
       61 cagaataatt cgctaattct ttttttaggg cgattgattt gtacttccgt cgcatcaatc
      121 attatcgtgt cctcagagct gagaggagtt cttgaaatcg taacaccacc tttgaacaag
      181 agttacttca acccattggc tccgacggat aaagaagact tgataagaac tctagagtta
      241 gctccccatg ttgaaggtgg ctattttaga caaacaaaaa aagcttcaga cactataaac
      301 cttgctggta agggaagggc gctttatacc agtatttatt tcttattaga agaaacgaat
      361 ccttcacatt ttcaccgatt gacagcagat gaaatctggt attttcatgc aggatcccca
      421 cttactgttc acatgattac agcagatggt cactacgaag cagtcacttt aggcctggac
      481 atatccaaag ggcaacaact tcactactgt gttcctaagg gcactatttg gggatcaaca
      541 gttgataagg attatgctct ggtttcttgt cttgttgctc ctggttttga atttgaggat
      601 tttgaattat ttgaaagggt agatctactg gcgacctatc cagagcacaa ggagatgatt
      661 gagcgtttga ccagatacta gtcttgataa gcaaatttaa tctgatttag caatgttagg
      721 atttctgata attgtgttat aatgttacca ataggagata atagatgaca aaacaagtct
      781 tattagtgga tgatgaagaa cacattctga aattgcttga ctaccattta agtaaggaag
      841 gcttttctac tcaattggta acaaatggac ggaaggcctt agctttggca gaaacagaac
      901 cctttgattt tatcttgctt gatatcatgt taccacaatt agatggcatg gaagtttgta
      961 agcggctgag agccaaaggc gtcaaaactc caattatgat ggtttctgcg aaaagtgatg
     1021 aatttgataa ggttttggcc ttggaattag gggctgatga ctacctgacc aagcctttta
     1081 gccctagaga attgctggcg cgtgtcaagg ctgtcctcag gcgaactaaa ggagaacaag
     1141 aaggagatga ttcagataat atcgctgacg attcttggct atttgggacc ttgaaagtat
     1201 accctgagcg tcatgaagtc tacaaggcga ataagttact gagtttgacc ccaaaagaat
     1261 ttgaactctt gctctatctt atgaaacatc ccaacatgac actgactaga gagcgtcttt
     1321 tggaacgtat ctgggggtat gactttgggc aggaaacacg tttggtggac gttcatattg
     1381 gtaagttgag ggaaaaaatt gaagacaatc ctaaagcccc tcaatttatt cgaaccattc
     1441 ggggttatgg ttataagttc aaggagttat agatgaaacg ctaccttcaa ttttggctag
     1501 tcaatctaag tgttagcctc attctgattg cagggatggc attaacttgg atcagtaaag
     1561 gcatcggtct ctttcttcta gccctttctt tgggacaagg tggctactgg ctcttttgcc
     1621 tttggaaatg ggaagttgct tttgagacct tgcaccaacc tctcttgacc agtagtgaat
     1681 actttttaga aaaagggcaa gaagacttaa agtctttggc tcagtatgtg tctgccctaa
     1741 aaaccaaagt ctcccaacag gatcagcaat acaaggacct agccgaaaca atggaggttc
     1801 ttctgtcgca cctaaccatg gggacgtttt tagtttccgc tcaaggtcag atgttattat
     1861 ccagtcgctc tctgcctcat tattttcccg atgtggacgg cgacataagt tcacttgatg
     1921 acctcaaacg gatggatatt cgaaatttag ttcaccaagc ctttgatcaa aaaacaaggt
     1981 taaaacaaga agtaagtggg tttcatgagg gtgacttgat tttagaagtg acagcagttc
     2041 ccgtttttag ccccacccaa tctgtggaag ctgtgctcgt cttgctatat gatttaacaa
     2101 cgattagaac ttatgaaaag ttaaatttag cctttgtctc aaatgcctcc catgaattga
     2161 ggacaccagt tacttcgatt aagggctttg ctgaaaccat taaggggatg tcagctgaag
     2221 aagaagcgct caaggatgac tttctagaca ttatttacaa agaaagcttg cgtcttgagc
     2281 atattgttga gcatcttctt accttatcta aggctcaaca aatgcctata caatggacga
     2341 ccctttcttt ggcagaattt gtacaggatt tgactcaaag cttgcaacct cagctcaaga
     2401 agaaggattt acagctaaag gtgcaggtgc cagatgatgt caccctcgta tcagatagtc
     2461 aattactttc ccaaatctta ctcaatcttt tatccaatgc catccgttac actgaacaag
     2521 ggggaaaaat tgaggtcaag acccaaaagg tgaacgaagg cattaagatt tctgtatcag
     2581 atacagggat tggtattagt caattagagc aggatcgtat ttttgaacgt ttttaccgag
     2641 ttaataaagg tcgaagcaga caaactggtg gcactggtct tggccttgcc attgtcaaag
     2701 aactcagtca attattaggt ggccaagtca cggtgacgag tcagcttggc agaggcagtt
     2761 gcttcacgat ttttcttcct aaccaatctt tcgcacagga ctaataattt ttaaagctat
     2821 ttttaggagc agccattttt caaaagtggc tttttttgat tctttacaca atctttacat
     2881 gaatcaggga taaaccttta caaagacttg ttagactata aatgtagtaa gcctacacaa
     2941 gaaaaataca tagagataaa ggtgattatt atgaaattca aaaaaatgct tactcttgca
     3001 gccattggct tatcaggatt tgggcttgtt gcctgtggca atcagtcagc tgcttccaaa
     3061 cagtcagctt caggaacgat tgaggtgatt tcacgagaaa atggctctgg aacacggggt
     3121 gccttcacag aaatcacagg gattctcaaa aaagacggtg ataaaaaaat tgacaacact
     3181 gccaaaacag ctgtgattca aaatagtaca gaaggtgttc tctcagcagt tcaagggaat
     3241 gctaatgcta tcggctacat ctccttggga tctttaacga aatctgtcaa ggctttagag
     3301 attgatggtg tcaaggctag tcgagacaca gttttagatg gtgaataccc tcttcaacgt
     3361 cccttcaaca ttgtttggtc ttctaatctt tccaagctag gtcaagattt tatcagcttt
     3421 atccactcca aacaaggtca acaagtggtc acagataata aatttattga agctaaaacc
     3481 gaaaccacag aatatacaag ccaacactta tcaggcaagt tgtctgttgt aggttccact
     3541 tcagtatctt ctttaatgga aaaattagca gaagcttata aaaaagaaaa tccagaagtt
     3601 acgattgata ttacctctaa tgggtcttca gcaggtatta ccgctgttaa ggagaaaacc
     3661 gctgatattg gtatggtttc tagggaatta actcctgaag aaggtaagag tctcacccat
     3721 gatgctattg ctttagacgg tattgctgtt gtggtcaata atgacaataa ggcaagccaa
     3781 gtcagtatgg ctgaacttgc agacgttttt agtggcaaat taaccacctg ggacaagatt
     3841 aaataaaatg tttgctccat aaatctctaa agagatgcag acgtttcatc gtacaataag
     3901 ataaagaagg caagtaggga ggtgtcgtat ctcccttact ttcttcacta gaaaggacaa
     3961 gatgtgacaa aacaagcctt caaagaagca gtttttaggg caattttttt catgagtgca
     4021 acagtagctg ttgtagctat tttgctaatc tgtttcttta tttttagtaa tggcttacct
     4081 ttcatggcta actacggctt tgcccgtttt ttattaggca gtgattggtc gccaacgaac
     4141 attccggcaa gctatggtat tttaccaatg atcgttggtt ccttattaat taccttagga
     4201 gcgattgtga ttggggtgcc aacaggcatc ttgacatcgg tgtttatggt ttattattgt
     4261 ccaaagcccg tctatggctt cttaaaatca gctatcaact tgatggcggc cattccatct
     4321 attgtttatg gttttttcgg cctacaatta ttggtgcctt ggattagaac ctttttagga
     4381 aatggcatga gtgtcctaac cgcttcgtta ctattaggaa taatgatttt gccaaccatt
     4441 atcagtttgt cagaatctgc tatccgaaca gttcccaaaa cgtattattc tggtagcttg
     4501 gctctaggag ctagtcatga acggagtatt tttagtgtca tcttgccagc tgcgagatct
     4561 ggtattttat cagcagttat tttaggaatc ggtcgcgcag taggtgaaac catggcagtt
     4621 attttggtgg caggcaacca gccgattatt ccaagtggac tcttttcagg aaccagaacc
     4681 ttaacaacca atattgttct ggaaatggct tacgcatcag gtcagcatag ggaagccctt
     4741 attgcaacct cagcagttct ctttttcctt attctcttga ttaatgccta ctttgcctac
     4801 ttgaaaggaa aatcatctta tgagtaaata cctgctaaaa cttctcgttt attgtttttc
     4861 agctttaacc tttggctctc tctttttaat cattggtttt atcctcatca aaggcttacc
     4921 tcatctaagt ctatccctct tttcttggac ttatacttct gagaacattt cccttatgcc
     4981 agcgattatt tccaccgtta ttctggtctt tggtgctctt cttttagcct tgcccatagg
     5041 gatttttgct ggtttttatc ttgtggaata tacaaaaaaa gattcccttt gtgttaaaat
     5101 catgcgattg gcctcagata ccttgtctgg gattccttcc attgtttttg gtctgtttgg
     5161 catgctcttc tttgtagtct tcttaggttt tcaatactct ctgttatcag gaatcttaac
     5221 ctcagtcatc atggtgttgc cagtcattat tcgctcaaca gaagaagccc ttttatctgt
     5281 tagtgatagc atgcgtcaag caagttatgg acttggggca ggtaagttac ggactgtttt
     5341 tagaattgtt ctaccagttg ccatgccagg tattttagct ggagtgatac tagctattgg
     5401 ccgtatcgtt ggtgagacag ctgccctcat gtatacatta ggtacctcta ccaatacgcc
     5461 aagtagtctc atgtcttcag gtcgttctct agccctgcat atgtatatgc tgtcaagtga
     5521 ggggctacat gtcaatgaag cctatgctac cggtgtgatt ttgattatta ctgttttaat
     5581 gataaatact ctatcaagct tattatctcg aaaacttgtg aaaggagctt cctagtatgg
     5641 gaacattttc agtcagacac ctagacttat tttacgggga ttttcaagcc ttaaaaaata
     5701 tttcgattca attaccagaa agacagatta ctgccttgat aggcccatct ggttgtggca
     5761 aatcaacttt tctaaaaacc cttaaccgga tgaacgattt ggttccttct tgccatattg
     5821 aaggccaagt cctcttagat gagcaagata tttatagtag caaattcaac cttaatcagc
     5881 tacgcaagcg tgtagggatg gtttttcaac agcctaatcc ctttgccatg tctatctatg
     5941 ataacgtggc ttatggtcca aggacacatg gtattcgaga caaaaaacaa ttagatgcct
     6001 tagtggagaa atctttaaaa ggggcagcca tttgggaaga agtcaaagat gatcttaaaa
     6061 agagtgccat gtccttatct ggcggtcagc agcaacgcct ttgcattgcg cgagctttag
     6121 cagtagaacc tgatgttctg ttaatggatg agccgacttc agccttagac cctatctcca
     6181 ctttaaaaat tgaagacctc attcagcaac taaaaaagga ttatacgatt atcattgtta
     6241 cccataacat gcaacaagct tcacgtattt cagataaaac tgcttttttc ttaacaggag
     6301 aaatttgcga atttggagat accgttgacg tgtttaccaa tccaaaagat cagcgcacag
     6361 aagactatat ttcaggacgg ttcggataag gaaggaaaaa cctatgagaa atcaatttga
     6421 cttagaattg catgaattag aacaatcctt tttaggacta gggcaacttg tccttgaaac
     6481 agcttcaaaa gccttactgg ccttagcctc caaagacaag gagatggcag agctaattat
     6541 caataaggat catgctatca accaaggtca aagcgctatc gaattgacct gtgcccgttt
     6601 gttggccttg caacagccac aagtgtctga ccttcgattt gtgattagca tcatgtcttc
     6661 ttgttcagac cttgaacgta tgggagacca tatggcaggc attgccaaag ctgttttgca
     6721 actaaaagaa aatcaactag cccctgacga agaacagtta caccaaatgg gtaaattatc
     6781 cctcagcatg ctagccgatt tattggttgc ctttcctttg caccaagcct caaaagctat
     6841 tagtattgct caaaaagatg aacagattga ccaatattat tatgccttat caaaggaaat
     6901 cattggactt atgaaagacc aagaaacctc aattcccaat ggaactcaat acctttatat
     6961 cataggacat ctggaacgct tcgctgatta cattgctaac atttgtgaac gcctagtcta
     7021 cctagaaaca ggagaactag tggatttgaa ttaattcaac taatccttaa aagagaagag
     7081 tacgattaag tgctcttttt tatggttgta aaaaagttca tttgaacaat ttaagcagtg
     7141 tagatagtga ggagctgttt caattctatc gtgaacgagg gaatgctgaa aactttatca
     7201 aagaaaggaa agcaggattc tttggggata agacagatag ttcgaccatg attaagaatg
     7261 aagtacgtat gatgatgggc tgtctggctt ataatctcta cctcttttta aagcagctag
     7321 ctggtgatga agtaaagtcc ttgactatca agcgttttcg acgtctcttc cttcatattg
     7381 ccggaaaata tgtctctact gctagacgac atattctcaa attctcaagt ctatacgcct
     7441 attcaaaaca gtttcaagcc ttatttgata caatctgcca gataaatctg atactccctg
     7501 ttccatatag agctagaggg caggggaaaa catgcctaac agaataagtc accttatttt
     7561 aaaaatcgag catcaaacca agggaggagt ctgccctttt ttaggaaaaa atcaagacaa
     7621 atctcctcaa tcatgtctcg aacatcagaa attaagcaaa atcaccagaa ggacagtatt
     7681 tcaactagct tttctggtaa tttttgaact gtgtagttcg ctagtgctag atatgaataa
     7741 tttgggatga taaatctttc ttcctcaggt agcctatcat aatactcttc aaaaatctta
     7801 gcaaaaacac tctctttctt ttgggcgata gtttcatctt cgtatgtagg agtcctcatc
     7861 aagaaatact tcaattctag gtattcctta tccaactcta tataacttgg catcaacttg
     7921 taatcttcac cccccccaaa cgttcagcga tatattttaa ctttgttagt gttggtctgg
     7981 attctccatt ttcaattcta attaattgac ggatacttaa ttcagactca tcaccacaaa
     8041 attctgaacg actgattttt ttagccaaac gtaatctttt aattttttcg ccaaactctc
     8101 gcaacctaca agaacctcct gagttgttta cctctattta tagcatatac tgaatcaaac
     8161 tatctatcag atttcttctc actttaacta aagactaaga gtttatccct tcatctcggt
     8221 ctttgtgtat ttttccacca taccccagta atgcaagtgc aaaatcctct agaatatgat
     8281 agaataatgg aaagaactct atcaaggagg aaatcatgga aaaacaaacc gtcgccgtct
     8341 tggggcctgg ttcttgggga actgcccttt cacaagtctt aaatgacaat ggacacgagg
     8401 tacgtatttg gggaaatctt cccgagcaaa tcaatgaaat taatacctat catactaaca
     8461 agcactactt taaagatgtc gttctagatg aaaatatcat tgcctacacc gacttagcag
     8521 aaacattgaa agatgtggat gcgattttgt ttgttgtccc aacaaaagtg acacgacttg
     8581 ttgcccaaca agttgcacaa accttggacc ataaggctat catcatgcac gcttcaaagg
     8641 gattagaacc tgatagccat aaacgattat caactatcct tgaagaagaa attcctgaac
     8701 agctccgcag tgatattgtc gttgtttcag ggcctagtca tgcggaagaa accattgtgc
     8761 gtgacctaac tttaatcact gctgcttcta aagatttaca aacagctcaa tacgttcagg
     8821 agctatttag taatcactac ttccgacttt ataccaatac ggatgttatc ggggttgaaa
     8881 ctgctggtgc tcttaaaaat attattgctg tcggtgctgg agctttacat ggtcttggat
     8941 ttggtgataa tgctaaggca gccatcatcg ctcgaggttt agcagaaatc acccgcctag
     9001 gggtagcact cggggccagt ccattgacct atagcggctt atctggtgtg ggagatttga
     9061 tcgtaacggg aacttccatc cactctcgta actggagagc tggagatgct ctcggacgag
     9121 gagaatccct agctgatata gaagctaata tgggcatggt aatcgaagga atttcaacga
     9181 ctcgagcagc ctatgaacta gcccaagaac ttggagtcta tatgcccatt acacaggcta
     9241 tttaccaagt tatttatcac ggaaccaata tcaaagatgc catttatgac atcatgaaca
     9301 atgaatttaa agcagaaaat gagtggtctt aaccctctat agaaaggatt tttatgacat
     9361 caaaagttag aaaggcagtc atccctgctg ctggactagg aactcgattt ttaccagcaa
     9421 ccaaggccct tgccaaagaa atgttgccaa tcgtagacaa accaactatc cagtttatcg
     9481 tggaagaggc tctcaaatca ggtattgaag atattctagt tgtcactggt aaatcaaaac
     9541 gttctattga ggaccacttt gattcaaact tcgaattgga atataacctc aaagaaaaag
     9601 ggaaaacaga tcttttgaag ctagttgata aaacaactga catgcgtctg cattttatcc
     9661 gccaaactca tccacgcggt ctcggagatg ctgttttgca agctaaggct ttcgtcggaa
     9721 atgaaccttt tgtcgttatg cttggtgatg acttgatgga tatcacagac gaaaaggctg
     9781 ttccacttac caaacaactc atggatgact acgagcgtac ccacgcgtct actatcgctg
     9841 tcatgccagt ccctcatgac gaagtatctg cttacggggt tattgctccg caaggcgaag
     9901 gaaaagatgg tctttacagt gttgaaacct ttgttgaaaa accagctcca gaggacgctc
     9961 ctagcgacct tgctattatc ggacgctacc tcctcacgcc tgaaattttc caaatcctcg
    10021 aaaaccaagc tccaggtgca ggaaatgaaa ttcagctgac agatgcaatc gacaccctca
    10081 ataaaacaca acgtgtattt gctcgtgagt tcaatggggc tcgttacgat gtcggagaca
    10141 agtttggctt catgaaaaca tccatcgact acgccctcaa acacccacaa gtcaaagatg
    10201 atttgaagaa ttacctcatc caacttggaa aagaattgac tgagaaggaa taaaataaaa
    10261 taaaaagata aggttcaaaa aatgccttat cttttttcat tacacaaatt ttctttcaac
    10321 ttcgtcacat tcccattccc ttgtagaaaa gcaaaatggc gagtcctacg aacaagacta
    10381 ccgctcctaa tctctggctg gtattataca tccgtttttc tcctctaact ggaaagataa
    10441 ctgctagaaa tgcgccacca actgcaccac cgatatggcc tgctaggctg attcctggaa
    10501 tcagaacact tccaataatg ttaactacaa aaagtgtcag ataggattgc cctagctgtt
    10561 gaatataagg attgcgagtt gcatagcgaa gaacaataat cgcggcaaat agcccataaa
    10621 gagaggtaga ggcgcctgct gctaaggatt taggactaaa tacaaaaaca aagagattgc
    10681 ccatcattcc tgataaaaga tagagaaaga aaaactgctt agaaccgaaa atctcctcta
    10741 cctgccttcc aagataataa agtgaaagca tattaacaat gaaatgttcc cacccaatat
    10801 gaacaaaaat ggcagacaag agacgccaaa cctgctcggg aaagaggcga atagctggcc
    10861 catacatggc tccaaatcga aataatgtat ctgccctgtc aaagtttccg cctgcagtga
    10921 ccaacattag taaaaatacc aaggccgtca ctaagaggaa gaaactcgtc acagggtaac
    10981 gtctatcaaa gatttccttc atcaattaat acctcctgaa caggaatatc atggttttca
    11041 ggtataaagt cctgaatttg acaaggatat atcgtactca aagcacgacc agaaaaatgt
    11101 tccagatagc ggtcataata acctccacca tatccaatcc gatatccatc cgtcgtaaaa
    11161 gccaggccag gaacatgaat caaatcaatc tgagatgcat ccactacttc caaatctccc
    11221 tgtggctcca gtaaggcaaa ggaagttttt accaactgtt gcggatcata gaccacaaaa
    11281 tccatgcgcc ccttgggata ggtcttaggt gtcaaaacct tcttgccgtc cttcagcgcc
    11341 tgctcaatca gttcccgcgt ttgaaactca tgagaaaaag agaggtaggt tgcgatgacc
    11401 ttggcttctt gataaaaggg gtgttgtaaa attcgctcgg ttaaagcttg gtctatagcc
    11461 tgtttttgct cttgagatat agccttcatt tcatgcaaga cttgcttgcg taattccgat
    11521 ttcatagaca agccctctat tctgctgcct tctttttcag gaaactagac accgcagcca
    11581 ccccaatagc taagacttct tccttaggac tcatttgagg gtgatgaaga gcgtagggac
    11641 tatcgatacc tagccaaaac atcacgccat caacctttga aaggagataa ccaaagtcct
    11701 cgcctgtcat agcaggttcg atatcaatca actcgattcc gtctttctcg tcaaagaagt
    11761 ccatcagttc acgcgccaag gctggattgt tctcaacagg taggtatcca ccttgtttga
    11821 gttccacttc gacttccata tcaaaggcag ctgcaacccc ttctgcaact gtttttaccc
    11881 tcttttgcac caagagactc atgtcctgtg tcaaggcacg aatagttcca tgtaaaaaag
    11941 ctgtgtctgt gatgacattg ttggtggttc cagcttgaaa aacgccgaag gtcaccactg
    12001 ctccctcgat tgggttgaca ttgcggctaa caactgactg cacttgggtc acaaagtaac
    12061 tagccgccac caaggcgtca ttggcttcat gaggaaaagc tgcgtggcca cctttacctt
    12121 tgaaacggat cttcacctcg caagttcctg caaagagtgt atgagtatta gtcgcaatct
    12181 ggccgacttt caaatctgga cgaacatgga gaccatagaa ttggtttggc aaccaatctc
    12241 caaaagcacc gtcctcatac atgagcatac caccagcttc attttcttca gcaggctgaa
    12301 atagaaagag cagattattc ttgggttgct cctcaagggc gcgctcaaga cagcctaagg
    12361 caatggtcat atgaaaatca tgaccacagg catgcatgcg accttggtgt tgagaagtaa
    12421 aaggtagacc tgtttgttcg acgataggca ggccatcaat atctgtccgc caaccaatgg
    12481 ttcgctccgg ctgacttccc tgcaggtaga ccaaaatccc tgtccgccaa gtacgaattt
    12541 gaacaaaatc cttgcccgta gtcaatttct caatcacatc cagcaaataa gcctgagtct
    12601 tgaactcctc caagccaatc tctggaatct ggtgtaaagc tcgtctagtc tgaatcaaat
    12661 ctaacatcta tctgtcctcc gatatagcag aaagaggctg gaaaaagggt tccgcctctt
    12721 ttttactttt acaattacaa ggtacgaagc gcatcctcta gcgctgtttt ttgttgagtt
    12781 tgggcatcaa tttctttgat aatacgagct ggaacacctg ctactaccac gttttctggg
    12841 acatcttggg taacgatagc tcctgcagcg acaactgaac cactaccgat ttggactcct
    12901 tcgataacca ctgcattagc cccgataaga acattgtctc cgacacagac tggttcagca
    12961 ctagctggct caatcacacc tgccaaaact gcacctgcac caacgtggct attttttcca
    13021 acgatagcac ggccaccaag gatggcaccc atgtcaatca tggttccagc accgatttca
    13081 gcaccgatat tgataacagc tcccatcatg ataacagcat tgtcaccaat ttccacctgg
    13141 tcacggataa tagcacctgg ctcgatacga gcgttgatag cacgcttatc tagcaaagga
    13201 actgcagaat tacgagcatc ttgctcgaca acataatctt gattttctac caaaccttca
    13261 agaagcggag ccacgtcctt ccagtctccg aataggacat ttcctagttt gacaacagag
    13321 ctaggcacag cagttgcgag ttgcccctca aaggttactt tgacactggt tttcttttca
    13381 gcattggcga taaattggat aatttcttga gcgttcattt ttgtagcagt cataggtgcc
    13441 tcctggttcg ttataatgat acctattcta ccaaaaaagg cctcaaattt gaaacctttt
    13501 tgtctgtttt taggtatgat tttttaggga tgtgagataa aacgtgctgt cggtaaaagc
    13561 aagcccctac cgatacaacc taaaaatact cttcacaact atctccccgt gttttattga
    13621 ctattctagt atagcacact tttagaatta agaaaagact ttttatctac tttctttcgc
    13681 ttcttctata gacaaaaata tcatgggtaa aataatcaag gctatagcta gaaggaggga
    13741 ccaatccact actaatccta agaacaaaac actcaagaga gcagaagaga gaggttcact
    13801 ggcactgata acggaaacca ccaaaggaga aaccaaggac acagccttca tggaaatgaa
    13861 aaaagcaaaa gccgttccaa agaaagcgat aatgaggcaa atcaagatac tccaaatatc
    13921 aagagtaaag gaaagctgat aaaccggcga gaggacattg ctaaacaaac ctgccaaaat
    13981 catcccccac ccaaccgtag gaacaaaacc ataacgctta gcaaaaggtt ggggcaagat
    14041 aacattaaac ataacaccca tggcactcag caaacctgtt ataagagcta gcggcgtcat
    14101 ggataactga gagagatctc cctttgtcgc catcaagcaa acacccagca tggcaaccaa
    14161 aacatagaaa acagcgcttt ttgacgctcg tttttgataa accaagcgat tgtaaaagag
    14221 gataaagaca gggctaataa actgtaaaat agttgctgtc gtagcatttg agtattctaa
    14281 acagagatag aaaaaatact gaactgaaaa aatccccaaa atagcatagg ctaaaaaggg
    14341 caggtaattt ttcttgtctc gccaaatatc tagcacttgc gattttaatt gtattgcaga
    14401 ccaaatgagt acaagactcc ctgccagtgt caaacgcata gaggtaatcc agcccgaaga
    14461 cacctgataa tgagtaaaga agtactctcc taaaattcca cagattcccc atattaagcc
    14521 ggataggagc gaataaattt ttccgttaac aatctttttc tgatactgat tcataccctt
    14581 attgtaacac gaaaggaaaa aagtggcaat ccattgattg gccacttcat ttagagaatt
    14641 atcgtctcgc ccttgaagaa gaaggtcgtg tagtacttga gttactgcta tcgctagaac
    14701 tactacttga actgctggag ctggatggag ttggtagact ccccacaata ctagaccaag
    14761 cattctgata atccgcatca cttccgccaa tagcaaagcg ataacttgtc gctggcgctc
    14821 ctgacttatt agcccaatag ctggtaacag tcgaacctgt gacctctacc tcttttcctt
    14881 caacagaaac cttccctggt ttttgacctg ttgatttcaa gacttccgat ttcactacac
    14941 taggatctaa agcaaagcgc tcgttccccc aaatgcttgg ggaagcttgc tgaatcgcat
    15001 ttaccagatg agccatgtaa ttagagttat tagaataacc tgctctacgt gacaatgaat
    15061 gattatcatc atgcccaatc cagccaccta gggttaatct aggtgtcgaa agcatgagcc
    15121 acatattttc gtcttggttg gttgtaccag tcttcccaat ccaatctgca ttagccagag
    15181 taggatttaa agaagtcagg ttagacttga aggttgttgt cacacgagag gatagaactt
    15241 ctcgtagcaa tccctgcata atcgtcgcag tagcttttga atagacttga accggtttat
    15301 cctgatactc atacaccact ctaccatctg ctgcttcaat ctttgaaatc acatgcttct
    15361 gatgataaac tccattatta gctaaggtct gatagccatt ggtatgctgg gcaactgtga
    15421 cttcaatacc accacccatt ggcaagctct caataccgta ctcaggaatc tcgtaaccca
    15481 tcttttccat ataacccttg acatcaacac ccttttcacg gagcatacga taggtccagt
    15541 aagcagggat attccatgaa tagttcagag cttctcccaa ggtcatcatt cctgttccct
    15601 tgctattagc atacataatc ggattgccat tagcaaagtt tgttggatag ttagatagaa
    15661 tcgtttcact tcccatcaag ccctggtcaa tagcaatacc gtaggccagc aagggcttgg
    15721 tagtagaagc tggcgaacgt tttgtatcaa aggcatgatt attttgattt tcttgataat
    15781 tacgaccacc tacaaagcct agaatagcac ctgtttggtt atccatcaag acattcccta
    15841 cttctacacg acctgttcca tcgtctaaaa gatagccata atcagcaacc gcactttgca
    15901 tggcagaatg aattttctga tctatggtag tagtaatctt ataaccacca ttttcaattt
    15961 ccttggctgc caaatctcga taaaacttct gagttgcctc atttttcaac tccttagcgg
    16021 agacattgtc tctctgagct agatagtcat acatacgttc ttgagcttct gccaaagttg
    16081 taaagtataa atagtctcgt gaaattcctg taaccgtgcc cgatggtaaa aagtcctgtt
    16141 taaggtcata atccttgtac tgagaatact cgtctttgct taatgcacct gtacgataca
    16201 tactgtaaag aactgcctta gcccgtctta agccaatttc taggtcttca tcactcttca
    16261 actccccagt attttcataa ggagagtaag taatgggact ctgtggaagt cctgctaaaa
    16321 atgctgcttg aggaacagtc aactgactgg catctacacc gaaaattccc tcagctgctt
    16381 gccgagcccc tgcaatattc tgtcccttat tatttcggcc aaagggagcc acattgagat
    16441 aggtcgttaa aatctcatct ttattcatgg cgcgttccaa ggcaagagca tccacaatct
    16501 ctgccgcctt acgagccaag gtcggcgcat ccccaacaac ctgctgttta attagttgct
    16561 gggtcaaggt tgaaccccca ctagaggaac ccaaacctac aaatttcccc aaggtcgcac
    16621 gaatcaccgc cttgggtact acacccttat gttctttaaa gtgttcatct tctgtcgcaa
    16681 tgatagcctt cttcagattt tccgaaattt gctcagatga gatagaagtg cgcaacaaat
    16741 cactctctat ggaagcaatc accgtcccgt ccgaataggt aatctctgaa atagaagaga
    16801 tgtccttgac ctgattcacc aattcttctg tctgaggcac ccgaaccttg tcaaataagg
    16861 ccactccgta ccccaaagca atcccaactc ccaacattcc tcctagaaaa ccgagtacaa
    16921 agagtaagtt aaataaggct tttatactca gtaaaatagc tgggaaaatg gctgacttat
    16981 ctaaggtttt agattttttg gtacttgaac ctttcttgcc aggtctagct gattttttat
    17041 ttttttgttt ttgctggaaa aattccagca tttttcgttt taattcattt aattgatttt
    17101 gcatggattt cctcacttta tctattatac cacaaaaggg aaattttcaa taaaatagcc
    17161 actttcttcc ctattctgct aggctattgc ccaagtttgt gatacaatag gtagaaacaa
    17221 taattttaaa aaggagaaaa gacacatgca catttttgat gagctaaaag agcgtggttt
    17281 gatatttcaa acgactgatg aagaagcttt gcgtaaagcc ctagaagaag gtcaagtttc
    17341 ttattatact ggctacgatc caactgctga cagccttcac ctaggccacc ttgtcgcaat
    17401 cttgacaagt cgtcgcttgc aactagcagg tcacaaacct tatgcgctcg ttggcggtgc
    17461 tacaggtctc atcggagatc cgtccttcaa agatgctgaa cgtagtctcc aaacaaaaga
    17521 cacagtagat ggctgggtca agtctatcca aggacaactt tctcgttttc ttgactttga
    17581 aaatggcgaa aacaaggctg tcatggtcaa caactacgac tggtttggca gcatcagctt
    17641 cattgacttc ctccgtgaca ttggaaagta cttcacggtc aactacatga tgagtaagga
    17701 atctgttaaa aaacggatcg aaacaggaat ttcttacact gagttcgctt accaaatcat
    17761 gcaagggtac gacttcttcg tccttaacca agaccataat gtcactcttc aaatcggtgg
    17821 ttctgaccag tggggaaata tgacagctgg taccgaattg cttcgtcgta aggcggacaa
    17881 gactggtcac gttatcactg ttccactaat cacagatgca actggtaaaa aatttggtaa
    17941 atcagaagga aatgccgtct ggctcaatcc cgaaaagact tctccatacg aaatgtacca
    18001 attctggatg aacgtgatgg acgctgacgc tgttcgcttc ttgaaaatct ttactttctt
    18061 gtcacttgat gagattgaag atattcgtaa acaatttgaa gcagcgccac acgaacgctt
    18121 ggctcaaaaa gtcttggctc gtgaagttgt tacacttgtt cacggagaag aagcctacaa
    18181 agaagcactt aacatcactg agcaactctt tgcaggaaac atcaaaaacc tttctgtcaa
    18241 agagctcaaa caaggacttc gtggtgtgcc aaactaccaa gtacaggcag acgaaaacaa
    18301 caatatcgtg gaactgctcg tctcatctgg tatagttaac tcaaaacgcc aagcccgtga
    18361 agacgtccaa aacggagcca tctacgtaaa cggcgaccgc atccaagacc ttgactatgt
    18421 cttgagtgac gctgataagt tagaaaatga actgactgtt atccgtcgtg ggaagaaaaa
    18481 atactttgta ttgacttact aaactattca acatttatct ataaacaaag gagttaacct
    18541 cgagaaaggt aactcctttt tgctgttaat aactctcatc tatctatttt taatagacag
    18601 gctacgcagg acaatgcgca aggttgttag attatgtaag atagagagat ttgaaggact
    18661 gaaccaatta aataagccaa agccaatcaa actactattt acgacaacgg tatcctgaat
    18721 atttttcttg atgagtgttt gcaaagatga tgataacgaa tccaactctt ggaagaaatc
    18781 caaacgatta tctaacaata agatatcact catctgctta gaaatatctg cactctcatt
    18841 catcaccaca ccgatatctg atagagttaa agccgctgag tcattcaatc catctccaac
    18901 catcaaaata gtgtgacctg ctttctgcag tttctctact aactcaaatt tcccatcagg
    18961 tttcaagtct gtatagacct gatcaaaggg caaatctttg actaattcct ctgtcctaat
    19021 caaggtgtct cctgttgcca gaatcaattt tttcccctgt gccttaagtt tatccaaggc
    19081 tgtttttgct tcttttctca aaggagtatg aatgcagaac attccaatca attcattttg
    19141 ataagccaag aataagagat tgtagtgact cttgtactct tcaattaaag cattttgttc
    19201 tgaactgata tgaatctgct catcctgcat caagacataa ttcccaataa gaactggttg
    19261 gccatctata tgagatttga tccccttgct tgcgatatat tggagtttcc catgcatttc
    19321 ctcatgttca attccctcta tctcagcttg cttgacgatg gcattagcaa taggatgata
    19381 aatgtgttcc tcaagacagg cactgattct gagaatatct tcctcactat agtctccaaa
    19441 aggtaacacc ttttcaacta taggataact agttgtgatt gttcctgtct tatcaaacaa
    19501 gaaagtatca acttccagat atttctccag aacatctcca tccttaatca ccatttcacg
    19561 gttcaaccct tccttgataa ctgtcaaata agctacagga gtagagattt tcaaagcgca
    19621 ggagaaatcg accaatagga aagaaatagc cttagaaaaa gaacctgtca ataggtaagt
    19681 cagcccagcc cccaagaaat tatatttgac gactttatcc gccatcttga tgaaatagcg
    19741 ttgtttcgtt ttcttgtttt cttcagattt cttcatcaac tcaatcagct gtaaaatacg
    19801 gctgttcatc tgattatctg ttacacgaat gcgtaactct ccagtttcta atactgtatt
    19861 tgcacaaacc aaatcagact ctcttttttc aactggaaaa ctctctcctg tcaaggaact
    19921 ttcgttgacc atacctaaac ctgaaactac ttgtccatca aacagaattt catttccttg
    19981 agataagatc aagacatctc ctatttgaac atcggaactc ttgatactaa caaccgtatc
    20041 gccctgtact aggaatacat cgctctcttt tgcaagaaga ctctgttcta aatctgttgc
    20101 agtttttttc aaggaccact gatctaaatg attccccaaa tcaagcataa acatgatatt
    20161 gctagctgtc ttggattggt tcataaacaa ggacaataaa atagccgaac agtccaagac
    20221 ttccatcgtt agttccttac gcgctagtgt ttgataggct tctctaatat aacccaaagc
    20281 ctgataacaa gtccatatat agcgaatagg atacggcaca aaactacgaa aaagtacacg
    20341 cttaaccgct gcacctgaaa caatagaata agcactctct tctctacgaa tgggaagagt
    20401 catcaactca gaaactttcc ctttatcaat tctttttaaa aaggcttctg cattatctaa
    20461 tacagaaaag ccttctttta tgcgtagagt aaagtgctgt tgatccatgt aaaactggat
    20521 agactcaatc cccttttcat ctctcgccaa ggaacgaaga tagtcttgaa tatccaaggt
    20581 aagtgaaaaa gaagatgata gtcggatatg ttggtatcct ctatgtagca ctttaaaaga
    20641 catattattc acctataagg ctatctaatt gctcttcttt tttctcttgc tcgtacaaat
    20701 atttggcatc ttgcaagaca tcgtctccat gttgcttcac aacagaaaca gatgcatcta
    20761 gctcgtcttt caacttgtaa gccttagcca aagctttaga ataacctttt ttagcttcct
    20821 tacttgctaa gattttcaaa ccaagggtac caaatgcgac accacccaaa aataatgaag
    20881 attttttcgc aacttttgca acggttaata cttcttttaa catacttatt tcctccttat
    20941 cattattata tagcaattta gatataaaag caatttcatt ctataaattg gagaattagt
    21001 tttatttcta ctgaatctac ttattcctaa agttgctttc atttgcctct tttgatacac
    21061 ttaaactatg aatacaaatc tcaagcccaa acttcagcgt tttgcttctg cgactgcctt
    21121 tgcctgtcct atctgtcaag aaaatctgac tctgttagag actaatttca agtgctgcaa
    21181 ccgtcattct tttgacttgg cgaaatttgg ctatgtcaat ctagcacctc aaatcaagca
    21241 atctgctaac tatgacaagg aaaattttca aaaccgtcaa caaatcctag aagccggctt
    21301 ttaccaagct atcttagatg ctgtatctga cttgcttgca agctcaaaaa ctaccacaac
    21361 aattttggat atcggttgtg gtgaaggatt ctattctcgc aaactacaag aaagtcactc
    21421 tgaaaaaact ttctatgcct ttgacatctc caaagattca gtccaaatcg ctgctaaaag
    21481 tgaacccaac tgggcagtca attggttcgt tggcgacttg gcacgacttc ctataaaaga
    21541 cgctaacatg gatattctgc ttgatatctt ctcacctgcc aactatggag aatttcgtcg
    21601 cgttttatcc aaagacggta tcttgataaa ggttatccca actgaaaatc acctcaaaga
    21661 aatccgtcaa agagtacagg accagctgac aaacaaggag tattctaacc aagatatcaa
    21721 ggagcatttc caggaacact ttaccatcct atctagtcaa actgcctctc tgactaagac
    21781 tatcacagca gaacaactcc aagccctact cagtatgact cctctcctct ttcacgttga
    21841 ccagagcaag attgactgga gccaactgac agagattacc atcgaagcag agattttggt
    21901 tgggaaagca ttctaaacta gacttcccaa aggtataaaa cttaccgaaa atcttcaata
    21961 ttataaaaac gcataagaac aggtacacaa accttaatct tatgcgtttt gttatagttt
    22021 ccatacacat taaggggaaa tagttgaaat cagttctctt aataaccatt gaataccata
    22081 tactacattt accccaaata tgatataggc cgtataaatc aagtatttcg atttttcccg
    22141 cctcaaagaa tagatcttat acaaaataaa taaatttaaa ataataaata atagagacaa
    22201 aatcttcctc caaaatcaat cctaaaagta cacagtcaag catagctcta atctttattt
    22261 tcgattcgat ataacaaact tatcaatgaa tagtaagtga tataaggcca gtaccagacc
    22321 ccaaacgcta ccacgaaaag agaattcttg atgattgaga gtaaacaaat catggttacc
    22381 aatatagagg caggtcaaaa taacaaataa aatccaaaat aaatccgtcc atttatattt
    22441 tgaaaaatat ttttttaaca taatagcata tttttttgac tataataaca gcatatgata
    22501 aaatgtaagc agatacaaat aaaaaggaga aaagctcatg aacaaattaa tgaaatttat
    22561 ttcggttttt ttgacgtcaa ttgtgttaat tgtatcagcg attccaagtg tttcagctgt
    22621 atacgcttct gaacaagtat cacaaattga aacaaatatg gaacttcaac ctgtcacttc
    22681 tctaacagaa gaacaaatca atacacttgc aaacgaaatc caatcttttc atccagacgt
    22741 ctcacaacaa tggatcaaag aagtaattaa ccgacaatta caaggcgatt atacaatccc
    22801 acctacatac tctccattta gagcagcttg gcaaggtatt acagttaatc aaatgggtgc
    22861 tctattagat actgcaatag ctttagcatt aggaggaact actgcaggcc ttgcaaatct
    22921 aattaaagta aaaggaaaac atgcagcaaa aagtgctatt cgttcagcaa tttctagata
    22981 tctaggtagt tggtttgtaa atgatgttgc tttagaattt gctataaatt tattatcacc
    23041 ggggacttat ttagcacaat tatgggataa aaatgatgcc attcctaaca acggaaggat
    23101 taacttttaa tcatgagata tacaataaaa ttaattgggt ataacgtatt ttcgttgttt
    23161 atattcttta tcttatcaat gttgtttaaa gtttccttta ggtggtggat cagcattgca
    23221 atgacgactt cgtcgtacat tgtatataat tacttaaaga aaaagagaga aaaggaatga
    23281 tcttatacca gatcattcct tttctgcttt ctgtaaatcc ctcggagtgt gtttggcgct
    23341 ttgatacgaa gtgtcaaagc tgtataaacg ttactatttc caaaaaagta acagaaaatt
    23401 cctgctttgt aggactgctt tgggtgagta atagacatgt cgactcaccc tatctcctga
    23461 tggcgaaaag aatttagcaa tggtgcaagt tgttctgaac tcgagaaaaa acatgccgaa
    23521 atcgaagaaa agcgtgcaga acttgaagcg aagaagcaag aaatgttgaa gcgcttggat
    23581 aaatagaatt tagaaaacag aaaaaactaa aaagaatgta gggtttattt ccctacattc
    23641 ttaaaataac ttagtacata aatgacaatg ctgccactgc cgtcaatatt gcaaaaacta
    23701 ttttccaaat ttttttattt tttccaaaaa tcttatcagg taacaagctt attacaagaa
    23761 aggtaataaa caacaccaat ttaagtgtgt atatcataaa aacaccttct ttcctacaat
    23821 tatattataa tactttatgt aagcgaatac aagaggtatg aggtaatcaa ctacgaaaaa
    23881 atataaggct gaggacagta aaaaccagca tttaaagcct tcactgtatc taggatttcc
    23941 ctatttttag acaagattga cccaaatcta catcattaaa aaagcgaatt tcaatcgaaa
    24001 ctcgcttttt tacaagatgt attagtataa atttgtatct tatactcaat gaaaatcaaa
    24061 gagtaaacta ggaagctaac cgcaggttgc tcaaagcacc gctttgaggt tgcagataaa
    24121 gctgacgtgg tttgaagaga ttttcgaaga gtattagttc aagtgccaga tgtcttcgtt
    24181 atactgagcg attgtacggt cagatgagaa gaatcctgct ttagaaatgt taacgatgac
    24241 tttatccaac catgcgtcac ggtcttcgta gtcagcaagc atttgctctt tgactttgat
    24301 gtagtcttcc aagtcaagaa gagtcatgaa ccagtctttg ttgatcaatt cattgtaaag
    24361 acgttccaag cgctctttgt ttccagctgc aagaactgca tcactaacga tgaagtcaac
    24421 caatggtttg atagcttcac gagcgtagaa ttcgcttgat ttgtaagctg cttttgcgta
    24481 aaggtcgata acagtttctg aatcttcacc gaagatgtag atgttttctt ctccaaccaa
    24541 ctcagcgatt tccacgttag caccgtccat agtaccaagt gtcaaagctc cgttcaacat
    24601 gaatttcatg ttaccagtac ctgaagcttc tttagaagca agtgagattt gttctgagat
    24661 atcacatgct gggataagga agcttgctgc agtaacgttg tagttttcaa ccataactac
    24721 ttgcaagtgt ggagctactg ctggatcgtt agcaataact tctgacatgc aaaggatcaa
    24781 gtgaatgata tcttgagcga ttgtgtaggc tggagctgct ttaccaccaa agaagattgt
    24841 gattggacga gcagggatgt taccagcttt gatgtcaagg tatttgtgga tcacgtacaa
    24901 agcgttcatt tgttggcgtt tgtactcgtg aagacgtttg atttggatat caaagataga
    24961 atttggattg atttccacac cttggtgttc tttcaagtga cgagccaatt tacgtttgtt
    25021 gtgagccttg atgctttcca atttttcttt gacagctgct ttgtcttcat aagacaacag
    25081 tttttcaagc tcatctgctt catggtgcca accatctcca agaatctcat ccaagtagtg
    25141 agacaatctt gggttagcat gcataagcca acgacggaaa gtgataccgt ttgttttgtt
    25201 gttgaacttt tctgggtaaa ggtcgtagaa ggctttcaac tcagaatttt tcaagatttc
    25261 agtatggagt gctgcaaccc cgttaacact gtatccgtag tggatatcca tgtgagccat
    25321 gtgaacacgt ccgctctcat cgatgatttg aacagctgga tctttgtact ctgccttcac
    25381 acgacggtcc aattcttcga tgattggtac caagtgagga accacttctt gcaagaattc
    25441 aagaggccat ttttcaagcg cttcagcaag gattgtgtgg ttagtgtagg cagtcatgct
    25501 acgaacaatt gagattgctt cgtcaagatc gataccacgt gcagtcaaaa gacgaatcaa
    25561 ttcaggaatc accattgatg ggtgagtatc gttgatttgg acaactgcgt agtcagcaag
    25621 gtcatgcaag ttgcttcctt tttcgattgc ttcgtcgatg atcaattgcg caccgtttga
    25681 aaccatgaag tattgttgga agatacggag caattcacct tgacggtcac tatcatctgg
    25741 gtaaaggaag agagttaagt tgcgagcgat atctgtcttg tcaaagttga taccatcttt
    25801 aataatagaa gaatcaactg aatccaagtc aaacaaacgc aagcggtttt tagtcgctgt
    25861 ttcataacca gtaacatcaa tatcgtaaag agttgatgtc aaagtaaagt ctgcaaatgg
    25921 tacttggtag ctacggcttg agcgaaccaa ccagttttgc tctgtcaacc atgcatttgg
    25981 aattgtttct tgttggttgt ttttaagaac ttgttggaaa agaccaaagt ggtagttaag
    26041 accaacaccg tcaccattca aaccaagagt agcaattgag tcgataaagc aggcagccaa
    26101 acgtcccaaa ccaccattac caagagatgg ttccaattca acttcttcaa cttcgatcaa
    26161 gtctttacct gcagctgcaa gttctttttt aacatcgtcg taaagaccaa ggttaatcaa
    26221 gttgtttgac aagagtttac caatcaagaa ctcagctgag atgtagtaaa cttttttctt
    26281 accagtgttg actggttttt ggctgcttgc aagcttgctg tagttaagaa gagcaaggta
    26341 aagctcttca ttgctacatt ctgcaatggt tttattgtaa cgattttgta caaattcttg
    26401 tagtgataac atgtttagtt gtctcctgat tattgtctta tttctttaaa tctaccaaat
    26461 tttcattaat tcggcgataa attgttgtca agtcaagcaa accttcctcg acagctggtg
    26521 tcaattgatc ttcagtcata cgccaagacc agtttccacc aagggtagat gggaagttca
    26581 tacgagctgc ctcatccaat tctagtaaat cttgcatagt tgcaattgcc ataaagctaa
    26641 ctgatgaaaa tactgtacga agcatagcgt gtaccactgt ttcgtattct ttacggttcg
    26701 tgtaacgagc catgtactca cgagtcgcat catcaatctc attacggtac caaccaagaa
    26761 ccgtattgtt atcgtgtgtt cctgtgtaca taactgagtt agcaggtgcc aagtgtgggc
    26821 tatcaatgct ttcgtcttct gggttgaagg caaattgaag aatcttcatt cctgggaagc
    26881 cagtacgttc acgcaattcg atcacttcat ctgtcatgaa gccaaggtct tctgcgatga
    26941 tgtttagctc accaagttct tccttaacgg ctgcaaaaag cttgtagcct ggacctttca
    27001 cccactcacc aggtgctgct gtatcggaac cagcagggat ttcccagtaa gattcgaagc
    27061 cacggaagtg gtcgatacga acgatatcgt agattttgaa gctttcacgc aagcgttcaa
    27121 tccaccattt gtagccgtct ttgtccattg cttcccagtc atagattggg ttaccccaaa
    27181 gctgaccagt tacagaaaac tcatctggtg ggcatcctgc gatacaagta gccttaccat
    27241 tgacatctgt tttgaagaga tgtggatttg cccacatatc acttgaatct tccgctacgt
    27301 agattggcat gtccccaacg atttcgatgt ggttgtcgtt agcgtaagct ttcaatttca
    27361 accattgttg gaagaagaag tattgagtca cacggtggta aaccaacttg tctgccaatt
    27421 gctcacgata gctttcaagt gctgaagctt tacgagcacg agcatctgca tctggccatt
    27481 cagtccaagc aagattgtca aaatactctt tgatagccat atactcagca aagagctcaa
    27541 gccatgattg gttgtcttga gcaaatttct caaaatcttt aacatctccg acttcaaaga
    27601 aacgtttcac cgctttttct aaaagaggac gacgtgcata gtagatttta gcatagtcaa
    27661 cttcagacgc atcgctacca aagtcaactc cttcaaggtc acttgcttcc aacaaacctt
    27721 gctccaccaa gatatctaaa tcgataaaat gagtgtttcc tgcgaaggct gagaaagatt
    27781 ggtaaggaga atccccgtaa ctagttgctc ctaatggaag gatttgccag taacgttgtt
    27841 ttgtacggac caagaaatca acgaagtcgt aagcactttg accaaatgat ccgattccgt
    27901 aagctcctgg aagagaagag atgtgcatca acacaccact ttgacgtttt ttcataatag
    27961 cacctcgtgt gttaaaataa tggaacgttg cgtattttgc agacgcaaac gtttgcgtta
    28021 cttataagta tactcctttt caagcataat tgcaagcgtt tttaaaaaac ttttttgatt
    28081 atttttaagg aaactaactc attttagcaa agataactta aaactatcta atcctaaggt
    28141 ttgactctca cgagacagtc tacaaagtat aaaacctcct tagggagctt gaatttatat
    28201 gtaacaaagc acaaacgtct atagaaaata gatatagatt agaaacaggg aggtagcccc
    28261 tcctgatttc cctctttaga cagattccat atatttttat taaaaatact gtattcttat
    28321 ctatttcata cttttcttct attaaaatgc aaaattatgc tatcaaatca agcttaaaaa
    28381 ttttttaaaa tttttacaaa aaatacttgc aaccgttttc tatttgtgct atactaagct
    28441 cataaaggaa aacgtttgcg tttccttatc aataaaactt gctattcttt aggaggaata
    28501 cactatgtca tctaaattta tgaagagcac tgcggtgctt ggaactgcta cacttgctag
    28561 cttgcttttg gtagcttgcg gaagcaaaac tgctgataag cctgctgatt ctggttcatc
    28621 tgaagtcaaa gaactcactg tatatgtaga cgagggatat aagagctata ttgaagaggt
    28681 tgctaaagct tatgaaaaag aagctggagt aaaagtcact cttaaaactg gtgatgctct
    28741 aggaggtctt gataaacttt ctcttgacaa ccaatctggt aatgtccctg atgttatgat
    28801 ggctccatac gaccgtgtag gtagccttgg ttctgacgga caactttcag aagtgaaatt
    28861 gagcgatggt gctaaaacag acgacacaac taaatctctt gtaacagctg ctaatggtaa
    28921 agtttacggt gctcctgccg ttatcgagtc acttgttatg tactacaaca aagacttggt
    28981 gaaagatgct ccaaaaacat ttgctgactt ggaaaacctt gctaaagata gcaaatacgc
    29041 attcgctggt gaagatggta aaactactgc cttcctagct gactggacaa acttctacta
    29101 tacatatgga cttcttgccg gtaacggtgc ttacgtcttt ggccaaaacg gtaaagacgc
    29161 taaagacatc ggtcttgcaa acgacggttc tatcgtaggt atcaattacg ctaaatcttg
    29221 gtacgaaaaa tggcctaaag gtatgcaaga tacagaaggt gctggaaact taatccaaac
    29281 tcaattccaa gaaggtaaaa cagctgctat catcgacgga ccttggaaag ctcaagcctt
    29341 taaagatgct aaagtaaact acggagttgc aactatccca actcttccaa atggaaaaga
    29401 atatgctgca ttcggtggtg gtaaagcttg ggtcattcct caagccgtta agaaccttga
    29461 agcttctcaa aaatttgtag acttccttgt tgcaactgaa caacaaaaag tattatatga
    29521 taagactaac gaaatcccag ctaatactga ggctcgttca tacgctgaag gtaaaaacga
    29581 tgagttgaca acagctgtta tcaaacagtt caagaacact caaccactgc caaacatctc
    29641 tcaaatgtct gcagtttggg atccagcgaa aaatatgctc tttgatgctg taagtggtca
    29701 aaaagatgct aaaacagctg ctaacgatgc tgtaacattg atcaaagaaa caatcaaaca
    29761 aaaatttggt gaataaaaaa tttgttcaag gggggtggaa atcaaatccc cctttgaatt
    29821 tatcaataga gacacaaata atttagcttt cttataaaaa agtagtatcc tatgaaagga
    29881 gttaatatgg aaaagcaaca acctagtaaa gcagccctgc tgtctatcat tcctgggtta
    29941 ggacagattt acaataaaca aaaagccaaa ggttttatct tccttggtgt aaccatcgta
    30001 tttgtccttt acttcctagc acttgcaacc cctgaattga gcaacctcat cactcttggt
    30061 aacaaaccag gtcgtgataa ttccctcttt atgctgattc gtggtgcctt ccatctaatc
    30121 tttgtaatcg tttatgtact cttttatttc tcaaatatca aagatgcaca tacgattgca
    30181 aaacgcatta acaatggaat tccagttcca cgcacactca aagacatgat caaagggatt
    30241 tatgaaaatg gcttccctta cctcttgatc attccatctt atgttgccat gaccttcgcg
    30301 attatcttcc cagttatcgt aaccttgatg atcgccttta ccaactacga cttccaacac
    30361 ttgccaccaa acaagttgtt ggactgggtt ggtttgacca actttacaaa catttggagc
    30421 ttgagtacct tccgttctgc ctttggttct gttctttctt ggactatcat ttgggctttg
    30481 gcagcttcta ctttacaaat cgtaattggt atcttcacag ctatcattgc caaccaacca
    30541 tttatcaaag gaaaacgtat ctttggtgtt attttccttc ttccttgggc tgtcccagcc
    30601 ttcatcacta tcttgacatt ctcaaacatg tttaacgata gtgtcggtgc tatcaacact
    30661 caagtattgc caatcttggc taaattcctt cctttccttg atggagctct tattccttgg
    30721 aaaacagacc caacttggac taagattgcc ttgattatga tgcaaggttg gctcggattc
    30781 ccatacatct acgttttgac tttgggtatc ttgcaatcta ttcctaacga cctttacgaa
    30841 gcagcttata ttgacggtgc caacgcttgg caaaaattcc gcaacatcac tttcccaatg
    30901 attttggctg ttgcggcacc tactttgatt agccaataca ccttcaactt taacaacttc
    30961 tctatcatgt acctcttcaa tggtggagga cctggtagtg tcggaggtgg agctggttca
    31021 accgatatct tgatctcatg gatctaccgt ttgacaacag gtacatctcc tcaatactca
    31081 atggcggcag ctgttacctt gattatctct atcattgtca tctcaatctc tatgatcgca
    31141 ttcaagaaac tacacgcatt tgatatggag gacgtctaag atgaataact caattaaact
    31201 caaacgtaga ctgactcaaa gccttactta cctttacctg attggtctat caattgtaat
    31261 tatctatcca ctgttgatta ccattatgtc agcctttaaa gcaggtaacg tctcagcctt
    31321 taaactagat actaatatcg acctcaattt tgataacttt aaaggcctct tcactgaaac
    31381 cttgtacggt acttggtacc tcaacacttt gattatcgcc ttaattacca tggctgttca
    31441 aacaagtatc atcgtacttg ctggttatgc ttacagccgt tacaacttct tggctcgtaa
    31501 acaaagtttg gtcttcttct tgatcatcca aatggtgcca actatggccg ctttgacagc
    31561 cttcttcgtt atggcgctta tgttgaacgc ccttaaccac aactggttcc tcatcttcct
    31621 ctacgttggt ggtggtatcc cgatgaatgc ttggctcatg aaaggctact tcgatacagt
    31681 gccaatgtct ttagacgaat ctgcaaaact agacggtgca ggacacttcc gccgcttctg
    31741 gcaaattgtt ctaccacttg ttcgcccaat ggttgccgta caagctctct gggccttcat
    31801 gggacctttc ggggactaca tcctctctag tttcttgctt cgtgagaaag aatactttac
    31861 tgttgccgta ggtctccaaa ccttcgttaa caatgcgaaa aacttgaaga ttgcctactt
    31921 ctcagcaggt gctatcctca tcgcccttcc aatctgtatt ctcttcttct ttctacaaaa
    31981 gaactttgtt tcaggactta caagtggtgg cgacaaggga taatttatcc ccgccaccct
    32041 ttttcatttt atactcttcg aaaatctctt caaaccacgt cagctttatc tccaacctca
    32101 aagttgtgct ttgagcaacc tgcagctagc ttcctggttt gcactttgat tttcattgat
    32161 tattagcaat tgtcactgta aataatatcc ttgtagcaag caatttttct cctagacttg
    32221 aaataaagcg catttctcta tataataata ctcatataga aaacaccttt tagaaagata
    32281 cctatgcttc catatccatt ttcctatttt tcaagtattt gggggtttcg taagcccctg
    32341 tccaaacgtt tcgagctcaa ctggtttcaa cttctcttta ccagtatctt ccttatcagc
    32401 ttgtctatgg tacccattgc tatccaaaac agctcccagg agacctatcc gctagaaact
    32461 tttatcgata atgtctatga acctctgaca aatgaggttg tccaggatct ctctgaacat
    32521 gctacaattg tcgatggcac attaacttat actggaacag ctagtcaagc cccttctgtt
    32581 gtgattggtc caagtcaaat caaggaatta cctaaggact tgcaactgca tttcgataca
    32641 aatgaactag tcatcagcaa ggaaagcaag gaactgaccc gcatctctta ccgagccatt
    32701 cagactgaga gtttcaaaag caaagacagc ttgacccaag caatttctaa agactggtac
    32761 caacaaaatc gtatctatat cagcctcttc ctagttctcg gtgcgagctt cctctttggt
    32821 ttgaatttct ttatcgtctc tctaggagct agtcttctcc tttatatcac taagaaatca
    32881 cgcctctttt catttagaac ctttaaagag tgctatcact ttatcttgaa ctgtttagga
    32941 ttgccgactc tgattacact tattttggga ttatttggcc aaaatatgac aaccctgatt
    33001 actgtacaaa atattctttt tgttctgtat ctggtcacta tcttttataa aacacatttc
    33061 cgtgatccaa attaccataa ataggagatt tttatgcccg ttacgattaa agacgtggcc
    33121 aaggctgctg gtgtttcgcc ttcaaccgta acccgtgtta ttcaaaataa atcaaccatt
    33181 agcgacgaaa caaaaaaacg cgttcgcaaa gctatgaagg aactcaacta ccacccaaac
    33241 ctcaacgctc gtagcttggt aagcagctat actcaggtta tcggattagt tcttcctgat
    33301 gactcagacg ccttctacca gaatcctttc tttccatcgg ttctacgtgg catctctcaa
    33361 gtcgcatctg aaaaccacta tgccattcag atagcaacag ggaaagatga gaaggagcgt
    33421 ctcaacgcta tttcacaaat ggtctacggc aagcgtgtag atgggctaat ctttctctat
    33481 gcccaagaag aagaccctct cgtaaaactc gtcgcagaag aacagttccc cttccttatc
    33541 ttaggtaaat ctctatctcc tttcatccca cttgtcgaca acgacaatgt tcaagctggt
    33601 tttgatgcga ctgaatattt catcaaaaaa ggctgcaaac gcattgcctt tatcggagga
    33661 agtaaaaagc tcttcgtgac caaagaccgt ttaacaggct atgaacaggc gcttaaacat
    33721 tacaaactta ccactgacaa caatcgcatc tactttgccg acgagtttct ggaagaaaag
    33781 ggctataaat ttagcaagcg attattcaag cacgatccac aaattgatgc tatcatcaca
    33841 accgatagcc tcctagctga aggcgtttgt aactatattg ccaaacacca gctggatgtc
    33901 cctgttctca gctttgactc ggttaatccc aagctcaact tggcagccta tgtcgatatc
    33961 aatagtttag agcttggtcg tgtttccctt gaaactattc tccagattat taatgataat
    34021 aaaaacaata aacaaatttg ttaccgtcaa ttgatcgccc acaaaattat cgaaaaataa
    34081 gagactgggc aaaaagtcgt taaaagcaaa aacgcatact atcaggtatt gaaaaaactt
    34141 gatactatgc gttttaatgt gggaagattt acttcctttt ctactgaaat tgagtctttt
    34201 cccaagatct ttttatactc aatgaaaatc aaagtgcaaa ctaggaagct agccgcaggt
    34261 tgctcaaaac atggttttga ggttgtagat gaaactgacg aagtcagctc aaaacatggt
    34321 tttgaggttg cagatagaac tgacgaagtc agtaacatat atacggcaag gtgaagctga
    34381 cgtggtttga agagattttc gaagagtatt aatcactaat tatctatctc aacaaatctt
    34441 cctagaatat gaacattttc cgagacagag acaaaggagc ttggatccac ttgtgtcata
    34501 atctgtttaa attcattaaa ctctgcacgt gtaatgacag tgattaaaac tgcctttctc
    34561 tcgtgattat aggttccttc tgcatcgtgg atcatggttg ctccgcggtg caatttttta
    34621 tggatttttt caattacctt ctctggatga tttgtcacaa tcatggcctg catacgcttt
    34681 tgcttagtaa agactgcgtc tgtcacacgg ctagagacaa agatggtaat catagaataa
    34741 agagcgtatt tccaaccaaa ggtcaaacct gctatcagca tgatagttcc atttaccaag
    34801 aaagaaatac taccgacatt cttacccgtt ttcttacgaa tagtcaggct gacgatatcc
    34861 gtcccaccac tggagatatt gtttcgaaga gcaaaaccaa tccccaaacc cataacaaca
    34921 cccccaaaaa gggaattgat aatgggatcc tccgtcaagg ttgccacagg gacaaactgg
    34981 ataaagaagg aactcataga taccgtgata aaggtaaaga cggtgaactt atggccaatc
    35041 tgataccaag ctaagaccat caaagggaag ttaatggcgt agaagcttag cgaaatcgga
    35101 atatgaaaac caaaccagtg attactcaag gcagagataa tctgtgccag acctgttgca
    35161 ccactcgaat acacatgccc tggttggaaa aagaaattaa ctgctactgc tgataaaaaa
    35221 ccatagacca gagaggccga aatcttctca tcatactttt ctcgagagat actttgtaag
    35281 acacgtaaaa tttttatctg ataagcaaag cggcgcagat aatagcgcca ccgcttaatt
    35341 cgttttgttt gtttcatctt cttctacttg taagctgagt tcctctagtt gtttgagagc
    35401 gactgttgat ggagcttgtg tcattgggtc agttgccttg ttgttcttag gaaaggcaat
    35461 gacttcacgg atattttctt ctccagcaag caacatgaca aaacggtcaa gcccgatagc
    35521 caaaccaccg tgcggtggga aaccatagtc catggcttca agaaggaaac caaactggtc
    35581 attggcttct tcagttgaga aaccaagagc cttgaacatg cgttcttgaa ggtctttttg
    35641 gttgatacga aggctaccac caccaagctc ataaccgttc aagacgatat cgtaagcaat
    35701 ggcacgaacc ttagccaaat caccttctaa ttcgtgagca gtctcttcct gtggaagtgt
    35761 gaatggatgg tgggcgctca tgtagcggcc ttcttcttca gaccattcaa acatcggcca
    35821 gtcaaccacc caaaggaagt tgaacttatc attatcaatc aagccaagct ctttagcaat
    35881 acgtccacga agggtaccca gtgttgcatt aaccacttca agcgtatccg ccacaaagag
    35941 aaccaagtcc ttatcttcaa gagcaagcgc tgttgtcaat tcttcttgga taccagtcaa
    36001 gaacttggca actggtccgt ttaattctcc atcaaccacc ttgacccaag caagaccttt
    36061 ggcaccatac tgtttggcta cttccgtcat cttgtcgatg tctttacgtg aatagttgtc
    36121 cgcagctcct ttgaccacaa tcgcttttac agcaggtgct tctgaaaaga ctttaaagtc
    36181 tacacctttg accacttctg tcaagtcctg aagcaacatg tcaaaacgag tatctggctt
    36241 gtcagaaccg taaagagcca tagcatcatc gtatttcata cgagggaacg gtagcgttac
    36301 ttcgatgcct tttgtttcct tcatcacgcg cgcgatcaag ccttctgtaa tatcttggat
    36361 ttctttctca gtaaggaagg acgtttccaa gtcgacctga gtaaattcag gctggcggtc
    36421 tccacgcaag tcctcgtcac ggaaacattt aacgatttgg tagtaacggt caaaaccagc
    36481 attcatcaag agctgtttcg tgatttgtgg actttgagga agagcgtaaa aatgcccctt
    36541 attaacacga gacggcacta aataatcacg cgccccttca ggcgttgact tagaaaggaa
    36601 tggtgtctcc acgtcgataa actccaactc atccaaatag ttgcggatag agtgggtcac
    36661 cttggcacga agtttaagat tttccaacat ttctggacga cgaaggtcaa ggtaacggta
    36721 acgcaaacgt gtatcgtcat ttgcctcaat gccatcctta atctcaaatg gtgttgtctt
    36781 agctgtgtta agcacaataa gagctgtcac gtttaactca accgcaccag ttggcaactt
    36841 atcattggct tgctcacgcg cagcgacctg accagtcacc tcaataacaa attcgctacg
    36901 aaggctttca gctgttgcca taacctctgc agatactttt tcagggttga taaccaactg
    36961 catgattcct tcacggtcac gaagatcgat aaagatcaaa ccaccaaggt cacgacgacg
    37021 gccaacccat cctttcaagg ttatttcttg tccgatgtgt tcctcacgaa cacgaccagc
    37081 atacatacta cgtttcatta tttctctcct cttttattct gttactattt taccataaaa
    37141 gcgcaggctc ttcatgaaaa tcatcagaaa agtttgccag tctttaaaag tcaggtgaaa
    37201 gccctaaaaa ttagcgctaa tactcttcga aaatctcttc aaaccacgtc agcgtcgcct
    37261 taccgtaggt attgttactg acttcgtcag tttcatctac aacctcaaaa ccatgttttg
    37321 agctgacttc gtcagttcta tccacaacct caaaacagtg ttttgagcaa cctgcggcta
    37381 gcttcctagt ttgctctttg atttttattg agtataaaat cctagttttt caaagatttc
    37441 tgagaagttt tggctgattg tctcaagtga cacttgcact tcttctcggg tttggttgtt
    37501 cttgaccgtc acttgtccgc tttcgacttc gctctctcct agggtgatga gggtcttagc
    37561 cgcaaagaca tcggctgact tgaactgagc ttttagttta cggttgaggt aatcacgctc
    37621 tgctttgaaa ccttgttggc gaagagcctg taccaattcc aaggccttga tatttgcccc
    37681 ttcgcccaag actgcgatat agacatctag ggcgttttcg atagggaggg tcacaccttg
    37741 cttttcaagg atgagaagca ggcgctctac accaagtcca aaaccaaatc cagcagtttc
    37801 agggcctcca aagtaagcaa ccaaaccatc gtagcgacca cccgcacaga cggtcaggtc
    37861 attgccctca atctctgtga taaactcgaa aatggtgtgg ttgtagtagt ccagaccacg
    37921 caccatattg gtatcgatga tgtaatctac tccaagattt tccaacatct gacgcacagc
    37981 atcaaaatga gcttggcttt cttcatcaag aaagtccaag atagacggcg cattctctac
    38041 tgccaccttg tcttcttttt ccttagagtc caagacacga agaggatttt cctccaagcg
    38101 acgttggcta tccttagaca aggtctcctt gagcggtgtc aaatagtcaa tcaaggcttg
    38161 gcggtaggct gcacggctct caggatttcc aagagtgttg aggtgcaatt tgacaccttg
    38221 aataccgatt tccttcaaaa aatgggctgc catagcgatt gtttccacat cggtagctgg
    38281 attgctagag ccaaaacact caacaccaat ctggtggaat tggcgcaagc gccctgcctg
    38341 tggacgctca taacggaaca taggtcccat gtagtagaac ttgcttggct tttgcacttc
    38401 tggggcgaaa agtttatttt ccacatagga acggacaacg ggtgcagttc cttctggacg
    38461 gagggtaata tgacggtcac ccttgtcata aaaatcgtac atttccttgg ttacgatatc
    38521 cgttgtatct ccgacagagc gactgataac ctcgtaatgc tcaaaaatag gcgtgcgcac
    38581 ttctgcatag ttgtagcgtt tgaaaatctc acgggcaaag ccctcaacgt actgccactt
    38641 agcagactca gcaggtaaaa tatcctgcgt tccttttggt ttttgtaatt tcatagggaa
    38701 tcctctttaa acttaatagt cttattttac cataaataga gggattaaaa cagtaagaaa
    38761 aaaattagga tttagatatc atttttgaga ttaagaattg tcaaaaaaat agctagcaag
    38821 gaaagaccaa caaatagcat ccaagtcaac tgtatattcc atacggctac tagtgaaaaa
    38881 caagctgttc ccacaggtat ggataaggta aacaatagac ctaaaaaatt actagtacga
    38941 gctagaacct ctggagctag atttttcatg agcatggcac taatctttgg ttgaacttta
    39001 ccagacacat acagagtaaa gaagagaaat agcaaaccaa gcacgacttg attgaataaa
    39061 ttagccaaac caactagact aagtcctacg gtctcccaca tcatcaatct aggcaaggac
    39121 tgcttcccaa aataatcatt gcccgtaagg ctactgatga tgactgatac taaaacacag
    39181 aattgattga taaatagtgc ctctgtataa gaaaaattca agagagaatg gctcaaaaag
    39241 aagatattat aaattccacc caaagcgcca cccaaggaat taataagcaa gacagcaaag
    39301 agcataaaac caaagttttt ctgtccactt ttaagaaaaa cgagacgtaa atttcggtaa
    39361 attgttagga actggtcttt gatagaaagc ttctcatttt ttaagttttc accatcagca
    39421 gatgacattg acaggctcaa tttgcttttt cctaaaaaga ggatagtggc tgatactagg
    39481 aaaaagcagg cattgattcc cgcaacgaga gaaaaattgt tgaccgatag agctaagagc
    39541 cagactccga aagcttgacc accaatagct gaaatatagg tgatgaactg tgaaaaagaa
    39601 taagcctcca tcagatcatc ttcagctact ttttccttaa taagaggcat acgcaggcca
    39661 cctgcaaaat cactgatgat atcactaatg acattgatca aacacaggct agaaaaggca
    39721 aagagactag cttgctgaac aactagggct gctagaaaaa atagaaccgc ctgaaacaaa
    39781 ccgctataga ccatccattt gaccttgtcc ctcgtgtaat ctgcccgaat ccctgcaaaa
    39841 actgtaaaga gggtcggaag aatcatgaca atattcgcca tagcaacagc aaaagatgct
    39901 tgtgacaagg tcgatgcata gacgataaag accaggttga aaatcgaaac accaaaagca
    39961 ttgaagaagc gtgataaagt caaaattcta taagctggat ttctaaacaa tagtttcata
    40021 gataatctcc ctccttgttc taagttctac atcaagaata gctttagtat agcacttatg
    40081 aatttgcgaa acgattcttt tgaatatatg caacaaacaa aatgagcaaa aaaacgatag
    40141 aacttttgta atgacctgag agagggcaac agttctatcg cttcaaattt tttcttggtt
    40201 tgcagatatt caagaatcgg gagtttttct atagtattcg gcagatttat tacagccaag
    40261 catctcaaaa atacggacag catcctccat ctttttctgg ccttccttga ctctaccttg
    40321 cttgctatca aggagacctt ctgcccacag ataaacaatt cggaaatagg tctcattttc
    40381 cttgtagaaa tgctcttcga taacacgttt aaaataatag gcattggtaa attcttcaca
    40441 ctcaatacta gctaaaaagc cattcaatag tatagtatga aaaaggtttc gattgccaga
    40501 catttccatt agaaaatcgg atttacgtac catttctcgt acatatctag taaaaagaga
    40561 aacagataaa aatggagaac tgactgaaaa taaattgagt tcatagattc cccagatctc
    40621 ggtagaaaac aaataatcat gaaggacttt tccttcctct gctgttaagt ctaccctttc
    40681 atctatgctc ttcatataag acttgataat aatggcattt agaatatgtt tctgtttgtt
    40741 gtgagaatgg gcatgctttt atactccctg cgatataagt cctcaagagg tgctatattc
    40801 tttggttcca agacatctgt aatttctttt ctcaactcag aatctgtatc atactggaaa
    40861 cctcttgcca gaaagaggat ctcctccaca ctggcagata tattttccag agcaaataga
    40921 aacttttcca ccgaaagctc actctgacct gtttcaaaac gggacaacat agacggcgaa
    40981 aattgtcctc cggttgcttg tctcagtgag atatttcttg actctcgtaa ttgtctaaag
    41041 acttttccaa tctgctccat agacttcccc ttgattccgt attttcttca ttttatcata
    41101 tttttcagaa aattcatcaa aaacttgcca aattgtcaga attatgagaa aatagaggat
    41161 atttatcacg tggagggact gctatgagag acgatatcaa aatcaatgac cgtgctttgg
    41221 ccttgcaaga ccaaattatc gaaaaactag agaaagtttt tgatacagat gtggaattgg
    41281 atgtttacaa tctaggtctg atttatgaaa tcaatctgga tgaaacgggg ctctgcaaga
    41341 ttgtcatgac cttcaccgat actgcctgtg attgcgccga aagcctgcct attgaaatcg
    41401 tggcaggtct gaaacaaatc gagggtatca aagatatcaa ggttgaagtt acctggtcgc
    41461 ctgcttggaa aatcacacga atcagtcgct atggccgtat tgcccttgga ctaccacctc
    41521 gttaagcaga ccaatcactt ttaaagatga aaaaagcaag ccgaaaatgg cttgcttttt
    41581 gatactcaat gaaaatcaaa gggcaaacta gaaaactagc cgcaggttgc tcaaaacact
    41641 gttttgaagt tatggataga actgacgaag tcagctcaaa acactgtttt gaggttgtgg
    41701 atagaactga cgaagtcagc tcaaaacact gttttgaggt tgtggataga actgacgaag
    41761 tcagcccaaa acactgtttt gaggttgtgg atagaactga cgaagtcagt aaccatacct
    41821 acggcaaggc gacgttgacg tgatttgaag agattttcga gtatgagttt attttttacc
    41881 tgacttgtcc atattccaga agtctgtcac ggctccgcgt gaagcagatg atacgatgtg
    41941 ggcatattta ccgaggacac cacggctgta aagtggtggc aaggttgttt ctgccttgcg
    42001 tttttcaagt tcttcttcgg atacggccat agaaatttct ttggtatctt ggtcaaccgt
    42061 aacgatatcg ccggtacgga gataggcaat tggtccacca tcctgagctt caggagcgat
    42121 atgtccaaca accagaccat aagtaccacc agagaaacgt ccgtccgtca agagggccac
    42181 cttatctccc tgacctttac caacaatcat tgaagaaagt gatagcatct caggcatacc
    42241 aggaccacct ttaggtccaa caaaacgaac aacgactaca tcgccatcaa cgatttcatc
    42301 tgtcagaacg gcctgaatcg catcttcttc tgagtcaaag accttagctg gcccaacgtg
    42361 acgacgcact ttaacacctg ataccttggc aactgcaccg tcaggagcaa ggttcccgtt
    42421 caagatgata agcggaccat ccgcacgttt tggattttca agtggcatga taactttttg
    42481 gcctggagtc aagtctgcaa agtcagccaa gttttcagct acagtcttac cagtacatgt
    42541 gatgcgatct ccgtgaagga aaccatttgc caacaaatac ttcataaccg cagggacacc
    42601 accgacttcg tagaggtctt ggaagacata ctgaccagat ggtttcaagt cggccaagtg
    42661 aggcacacgt tcttgaatcg tattgaagtc ctcaagtgac aagtcaacat ttgcggcatg
    42721 ggcaatggcg agcaagtgaa gagtggcgtt tgtagaacca ccgagagcca tcgttacagt
    42781 gatagcatct tcaaaggctt cacgagtcaa gatatctgat ggtttgagac caagttccaa
    42841 catcttaaca acagcacgtc ctgctgcttc gatatcttct ttcttatcag ctgattcagc
    42901 tgggtgagag gatgaccctg gcaaactcat ccctagaact tcgatagcag ttgccatggt
    42961 attagcagta tacataccac cacaaccacc agggccaggg caggcattac attcaagacg
    43021 tttcacgtcc tcagctgtca tgtcaccgtg gttccatttt ccgatacctt caaagacaga
    43081 aaccaagtcg atatctttac catcaagatt tcccggtgca atagttccac cataggcgaa
    43141 aatagctggg atatccatat tagcaatagc aatcatagat ccaggcatgt tcttgtcaca
    43201 gccaccgata gcgacgaagg catccacgtt gtgaccactc atagccgcct cgatggagtc
    43261 cgcgatgatg tcacgagatg ttagagagaa acgcatacca ggcgttccca tagcgatccc
    43321 gtccgctacg gtaatggttc caaactgtac aggccaagcg cctgcagatt tgacaccttc
    43381 tttagccagt ttcccgaaat catgcaagtg aatgttacat ggtgtatttt ccgcccaagt
    43441 cgaaatcact cccacaatcg atgtttcaaa gtccttatct gtcataccag tcgcacgaag
    43501 catagcacgg ttaggtgatt taaccatgct gtcataaatg ctactgcggt gacgtttatc
    43561 taattcagtc atcttatccc tcccatttca gtttttacta ttatagcaca attttcgcat
    43621 gaagaacaga ataaaattct tgaattttca gaaaattcta tacacatgtg aaatatttaa
    43681 aattaaaaac aacaaagcgg attagtgcac tttctgatga ccagaatatg ctttttaatc
    43741 cgctttcttt aaataacgta ctgtaatttt tacagaaatt ctttcaaata agtgtattta
    43801 acatctatct tgcattataa atttctagaa ccttctcttt tatattcgat tcactcaaac
    43861 catactcatt aagaagataa tccattttcc ctacttgacc gaatctttct tgaacaccca
    43921 tccgatgaat ttttgttatt ccatcatcag agaataattc acataaagca ctgccaattc
    43981 cacctatctg attgtggttt tctacagtaa atatagtttt tccacttaac attgttttta
    44041 tctgttctgg tatcggtttg attctaaata aatctatcac acctactgaa taacctaatt
    44101 tagacagttc atctgcaact cgaatacttg gagcaaccat tatgccagaa gcaacgatta
    44161 caagatcttc accatgcctt aactcaatgt agcctttaga aaaatcttct ccaccttgat
    44221 acacaggaac tggagctttt ctaattgttc gaatatattt tagtcctttt aagtctaatg
    44281 tctggttcaa tatttcacga aattggatat catcagttgc ttcgaaaatg attgatttag
    44341 gaattaaacg taacaatcca atttcttcaa atggcatatg tgttccacca ttcatctctg
    44401 ccgttactcc tgcatctgat ccaatcacag tggcatccaa ttgtgcgtat ccaagagaaa
    44461 taaataattg atcaaatact cttcgtgaag caaaaggacc aaatgtatga agataaggtc
    44521 taaacccctg aatagacaag cctgctgcaa ggccgaccat ttctgcttcc ataatcccaa
    44581 cattcacata acggtctcca aagtcctttt caagattatt agtagccatc gaacttgaca
    44641 aatcggcttc taagactact atatcagaat cactttgatt agcctctaaa aggaagtctc
    44701 tatatacatg ccgtaattct ttcgtacttc tcatcattct gtttcctcca attcctgact
    44761 taatctttct acaactgaag ttaacatttg tttctcctct acagtagggc gaagatgatg
    44821 attggatttc atttcttcca gctcttgaac cccttgacct ttaatagtat ctaatacaat
    44881 gcacttaggt gatgaattat ttgactgttt taattggaca atcccttcat aaatttctct
    44941 aatatctgaa cccttgaccc taatggattc aaatccaaat gctgaaaatt tttctacgaa
    45001 atcacctgga ttacaaatat cctttgtaaa accatctaat tgttttttgt tatcatcaac
    45061 aaatacaatt aagttggata actgttgatg agaagcaaac tgtatagcct cccaacattg
    45121 tccctcattt aactcaccat ctccaacaat agcgtaagta taaaagggac tctttcttat
    45181 tctctgacca tatgcaagtc cagttgcaac actaattcct tgtcctaaag agcccgttgt
    45241 catatctatg cctggcgtta gatttctatc aggatgagac ggtaatttgg ttccatttgt
    45301 atttaaagaa tataagaatt ctttgtcaaa gaaaccattc aaatagagtg tactgtatag
    45361 agctggtcct ccgtgacctt ttgataatat gaaataatct ctatctcgtg ctgcaaatat
    45421 ttctggagtc attggcatta tttcaccata aagcaccgct aaaacttcta cgatagacag
    45481 acttcctccg taatgtccga atccaagatg attcaatgtt ctaagagtat ttaatcggat
    45541 gttagtcgca aattttctta acccatcttc tctattttta cttaaaatca tcccttattc
    45601 ctccgttgca gatggctttt taataaagga tactccaaac ataactgcta gaataagaac
    45661 aagaccaatc acaatgcctg cttgtgagcc aaattgattt aacattccta aaataattcc
    45721 tgatagacca aaatctgcat ctgagaaagt tgatccttgg aaaccaagtc ctcccaaaac
    45781 tggcattaaa aagactggaa gaaaactgat taaaatacct tgtaaaaatg ctccaatagt
    45841 ggctccacga acaccaccag atgcattccc aatgacacct gcagtcgctc cacagaagaa
    45901 atgaggcaca acacctggta agataacaac cgttcctgaa gcaatcataa ttaccatact
    45961 tactaaacca ccaacaaaac tagagataaa tccaattaga actgcattgg gtgcataagt
    46021 ataaacaatc ggacaatcca aagcaggttt tgaattaggt acaagacgct ctgaaatacc
    46081 tttaaaggct ggaacaattt cgcccaaaat aaggcgaaca cctgctaaaa taacaaatac
    46141 ccctgctgca aattgacctg ctaattgtaa agcataaact agaccacttg taccactact
    46201 gatttctttt tctatatatt ctgaccctgc aaagatagct acaataatgt aaataactgc
    46261 catggataaa gtaatactaa cagtactatc acgtaaaaaa gctaaactct ttggaaattt
    46321 aatgtcctct gttgattttg atttgtcacc gataaggcta ccagtaaaac cactcaacca
    46381 atatcccaaa gaactgaaat gacctaaagc taccttgtca tttccagtta attgaaccat
    46441 atatttttgc acaaatgctg gggaaatact cataataata ccgagtgcta atcctcctag
    46501 taagatgaga ggcaagctag taaagccagc aactgataaa atgaccgcaa tcatacatgc
    46561 catatataga gtgtggtgcc ctgttaaaaa aatatattta aatcgagtaa aacgagcgat
    46621 taagatattg aacaccatgc ctgcaaacat aatcattgca gtagctgagc catatgttgt
    46681 taaagctaca gctacaattg cttcattatt cggcacaacg ccagataaat gaaaagcatg
    46741 ctcaaacatg gtaccaaatg gatttaaaga attttgtaca attcctgcac caccagatac
    46801 aactaagaaa ccaacaaagg tcttaattcc acctttaata atatcaggta atttcttctt
    46861 ctgaagaact aatcctaaga ttgcaattaa agctactaaa atagctggtg tactaacaat
    46921 atccaatatg aacttcatca tgacgctagc ctcctatata agtccttttt cttcacaaag
    46981 tttagtaatt aattctcgta gttcatccat atcaataata ctatttaaga tacgaacatc
    47041 tccaagatga ctagctgaat cagctagatc acgaccaaca atccaaatat cagctgcatt
    47101 tggatctgct ccacctaaat cataatgttc aacttctaca tccgaaacat tcaaatcact
    47161 caatacagat tcaatattca tctgtaccat aaaacttgaa cctaatcctg aaccacaagc
    47221 tgtaccaatt tttaacatta tctaatcctc ctgtttaatt atcattttaa tgtcatcata
    47281 gttttttgat gatattaaag tttgaacatg atttttatct cttaaaattg ttgttaaatg
    47341 tgacaaagcc tttaaatgac tctcattatc aatggctgca atacaaatca acaatcttac
    47401 ctcttgttct ggattatcca ataaataaat cggttcttcc aaaactaaca ttgacattcc
    47461 tatttcattc acaccttcat ctggccgagc gtgaggaatt gctactccct tccctaaatt
    47521 aataaaaggt ccaaactctt ctactttttg aatcattgcc tcagggtagt tctcagttat
    47581 cttatcttga tccaaaagcg gtttagctgc taaacgaatc gcctccttcc atcctaattt
    47641 ttgcgaacta acctgatagg tttctttggt aataagttgt tctagcactg gtacaatttc
    47701 ctttctatca tttttttggt aaagataatt ctttaacgcc aatcttaatt ccaattcttg
    47761 tgtaataatt ccatatcttt tgacaatatt caggatttgt tcaatctcaa aatctccata
    47821 ctctaaattc ggaaaatctt ttaacactag ttctactagt tgtattgctt gctcttcagt
    47881 catcataacc gaaactagat aatttggctt ttctgtctcc acctttatgg tagaaaaaac
    47941 catatcatag tcactactag ctttcacctg taaatcatca atctttgagg ttcctataaa
    48001 ctcaatttga ggaaataatg ctaatagatt ctcttttaac atcaatgaag aactaacacc
    48061 attaggacaa atgattgctg ctttatacca tttttgaggc aaagtatctg ctttctttaa
    48121 ataacctccg aaatggataa caaaatatgc tgtttcacta tcaggtatgg gattgtcaat
    48181 agcgtccatc aagggcatca aagaatcttt gactaattca aataaatcag gataatgttc
    48241 tttaacatgc aatacatatt catttgaact aggtaggccg aactttaatc tatagtaagc
    48301 cggtataagg tggcggcgaa gattttctct caatccttcc ctttgtttaa aatgtaacaa
    48361 agaaatatct tccattctac ttataatagc ctctgttaat tgattaaagt aaaccggagc
    48421 aacatctact tcaccttcaa agcaacttga taataaaacg gtgatatagc gataatcatc
    48481 ctcagaaaac accgtatcta taattcccaa atcaaccact gtatccaata aaatagtggt
    48541 tatatcttga ataacaggag atactaatgt ctctgaaaga catactcttt caacatccct
    48601 ttgataccta cacagaatga atactaaacc gaaaaggtaa acttttaatt gattaacaat
    48661 aggtactagc tgtagcttct cataataatc tttaactacc tgatcaatca aatcataagt
    48721 taatgaatac ccccaactgg ataaaacata atccaaaccc caaatcccta tggaggattc
    48781 cagcaactca ctaaccattt gaaaagctaa gcggtgctta ttccactctg aaccgtgtaa
    48841 agtataacct tttgctctac tgtaccctag ctccaaatca ttatctaaca taatctttct
    48901 taatgattga atatcagata aggttgtatt cttacttact ttcaaaaagt cttggtaatg
    48961 actattcgat ataaaatcta atcggcaaaa agtgtaaaga tagattaaag ctaagcgagt
    49021 cgactttggt aaaaccaatt catccgactt aataatatct gtcaaagact gcttcgtacg
    49081 atttgataaa ctatagcgac cttgcttttt atccagcact atccctttat tagctagata
    49141 aggcactaaa taatctattc cttctttgac ttcctttata ggtaagctca ccttaacaga
    49201 taattcatat aatgatagct cacaatgatc catcaaagtc atcaaaataa ctagtgctct
    49261 ataatcaaac atttctcttc ctttctaact acaattatag tgtaaaaatt ataagaataa
    49321 aagagtattt gagcacaata taatctcacc ttttaaaaga aattattggg ctgaaagttt
    49381 ttagtgatta tttttcaact ttctattgac tttataaatt aaagtgatat catttagata
    49441 tcaaataaca ggaggtcatt cttatgactg aaaaactaat caattcaaaa ccaaatggtg
    49501 tattcgcatt gattctcatt gagttgacaa tcgtacttgg tatctttata tttataatgg
    49561 gggttggttc ggaaaacatt tttggaatta ttatcggacc tttactaatc gtaattgcag
    49621 gtctagctca tgctggttta aaagttgtca aacctcaaga agctctggtt ctgacactct
    49681 ttggtaacta tacaggtacc atcaaagaac ctggctttta ctttgtcaat cccttcagcg
    49741 tagcagtcaa ccctgcaaac cacactcgac ttggacaaag tggtgatgtt agcacaaaat
    49801 ctcctttttt aggagctaaa tcatcaaatg acaatgatgt aaatcttgaa attggcaaga
    49861 aacagatttc cctcaaagtc atgaccttga gcaattctcg tcaaaaaatc aatgattgct
    49921 taggaaaccc tgtagaaatc ggtatcgcgg taacttggag agttgtcgat accgctaagg
    49981 cagtcttcaa cgttgataac tacaaagaat atctttcatt gcaatgtgat agcgccctcc
    50041 gtaatattgt ccgcatctat ccttacgatg tgtctcctaa tgtggatact acgggtgatg
    50101 ggcaagcaga tgaaggtagt ctccgtggct ctagcgaaat tgttgctaac cgtattcgtg
    50161 aagaaatcca aagtcgtgtt gaggatgctg gcttggaaat ccttgaagca cgtatcactt
    50221 acctagctta tgctccagaa attgctgccg ttatgcttca acgccaacaa gcatctgcca
    50281 ttattgatgc acggaagatg attgtagatg gtgctgtagg aatggttgaa atggcactag
    50341 aacggctcaa tgaaggggaa ttggtagaac ttgacgaaga acgaaaagct gccatggttt
    50401 caaatctcct tgtcgttctt tgtggcaatc atgatgcaca accaattgtc aacacaggaa
    50461 gcctttacta aagatggctg aagctaaaaa aaagcagatc ccccttcgac tctcaacaaa
    50521 gttatacgct gcactcgcat catgggcaga agacgacttt cgttcagtca atgggcaaat
    50581 cgaatatctc ctcacagagt gtgtcaagca acggaagaaa gacggaaaat acgtatcaga
    50641 aaccattgac gaaccatttg agattgatat ttaacacctt ctcctgtctg ccgtgtcgga
    50701 taggagaatt ttttcatctt tttttgtcaa gtaactttac tttacaaaaa aaatgtgtta
    50761 tcctagtatg gttgatgaaa atcagtagat tgaatcgaat ataaatacct aaaggagaaa
    50821 tcaaaatggc agtacctgca cgtcgcactt caaaagcgaa gaaaaacaaa cgtcgtacac
    50881 actacaaagt aacagctcca tctgtaaact ttgacgaaac tactggagat tactcacgtt
    50941 ctcaccgtgt atcacttaaa ggatactaca aaggacgtaa aatcactaaa gctgcatcag
    51001 ctgaataata gaagggagat accatgcgcg taaatattac acttgaacac aaagaatctg
    51061 gtgaacgctt gtaccttact tctaaaaaca aacgtaacac tccagaccgc cttcaattga
    51121 agaaatactc accaaaactt cgcaaacacg ttgtgtttac agaggttaaa taagcattca
    51181 atacgaatca atacagaaga aaaacgcttg atcagcgttt tttctttttg ttaatttcac
    51241 tacattgtaa gggaaatcat tcgaatgact acatttttca ctaccttttt tgaaataaga
    51301 atacggattc ggacaattaa aagcaagagg aactcaaatg taagttgggg ttcctttttt
    51361 gtatattttt caaataacgc ctctacacta tttgtagcaa attcaccaac tacagttgta
    51421 tcttagttaa aataagttag aatatgtaag tgagtaccag atataccaag acatcgtcac
    51481 catctaaggt atattcaaaa tacaaaagtt gaccaactag atttctgaat atccttatat
    51541 atccattctt aaaattggtt taaatagcgt agtcttttaa actagttttg agaatccaaa
    51601 aaatcttcct acatatgtaa gaagattttt tagttcagaa tgattagatt tagctaatgg
    51661 atacctatcc tacccactca ccgttagcat tgactcgata gccatcgggt gtagtcgtgt
    51721 ttactaataa atctcctgaa ttataggtat agtaccattt accagaaact gtaacccaac
    51781 cagtagccat tgaacctgat tcatttaagt a
//
LOCUS       DAVBCA010000005        51676 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.005, whole genome shotgun sequence.
ACCESSION   DAVBCA010000005 DAVBCA010000000
VERSION     DAVBCA010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 51676)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51676)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51676
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.005"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(54..362)
                     /locus_tag="VQU19_000262"
                     /pseudo
     CDS             complement(54..362)
                     /locus_tag="VQU19_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
     gene            complement(604..900)
                     /locus_tag="VQU19_000263"
     CDS             complement(604..900)
                     /locus_tag="VQU19_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2479580.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYSKMK"
     gene            complement(884..3043)
                     /gene="pfbA"
                     /locus_tag="VQU19_000264"
     CDS             complement(884..3043)
                     /gene="pfbA"
                     /locus_tag="VQU19_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HET2479581.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVISTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRESGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVIN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SFIKSNANGKESVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            complement(4173..5399)
                     /locus_tag="VQU19_000265"
     CDS             complement(4173..5399)
                     /locus_tag="VQU19_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HET2479582.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVFEVGPGDEVIVPAITYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            complement(5442..6134)
                     /locus_tag="VQU19_000266"
     CDS             complement(5442..6134)
                     /locus_tag="VQU19_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HET2479583.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGNLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSTEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFKVLK"
     gene            complement(6320..8071)
                     /locus_tag="VQU19_000267"
     CDS             complement(6320..8071)
                     /locus_tag="VQU19_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2479584.1"
                     /translation="MQNKQEQWAVLKRLMSYLKPYRLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLVYANRSVALDALFLRPAMSLLKLLGYAVLMAYFGYRGLSIG
                     ITAGTMYAFIQYINRLFDPLIEVTQNFSTLQTSMVSAGRVFALVDERTYEPLQENGQA
                     KVQEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLALGG
                     TYHKMYSLQAGAMAYTL"
     gene            complement(8061..9806)
                     /locus_tag="VQU19_000268"
     CDS             complement(8061..9806)
                     /locus_tag="VQU19_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2479585.1"
                     /translation="MSIIQKLWWFFKLEKHRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSPAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTELRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSEVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILNPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADFILVLQNGQIIERGRHEDLLAMDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            complement(10012..10308)
                     /locus_tag="VQU19_000269"
     CDS             complement(10012..10308)
                     /locus_tag="VQU19_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001276342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HET2479586.1"
                     /translation="MSASDVALKLRSQGIFQMKQVKRAVQEQNGQLIVVQMGDENPKY
                     PVVTDGVIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYE"
     gene            complement(10461..10917)
                     /locus_tag="VQU19_000270"
                     /pseudo
     CDS             complement(10461..10917)
                     /locus_tag="VQU19_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            11051..11878
                     /gene="xth"
                     /locus_tag="VQU19_000271"
     CDS             11051..11878
                     /gene="xth"
                     /locus_tag="VQU19_000271"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HET2479587.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            11890..12033
                     /locus_tag="VQU19_000272"
     CDS             11890..12033
                     /locus_tag="VQU19_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HET2479588.1"
                     /translation="MDYNAVIPEFLVSNIEQSRSFYCGLLGFRIEYQRSEENFLFLLK
                     SVN"
     gene            12033..12272
                     /locus_tag="VQU19_000273"
     CDS             12033..12272
                     /locus_tag="VQU19_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HET2479589.1"
                     /translation="MLEEGTKDQLAELTYPFGRGVNLSFGIKDVPKLYQKVMEANYPI
                     YRPLTKRKFRVSDPYIYPHKFAVLDPDGYFLRFSE"
     regulatory      12656..12751
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            13151..13732
                     /locus_tag="VQU19_000274"
     CDS             13151..13732
                     /locus_tag="VQU19_000274"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HET2479590.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAAAGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     gene            13732..14994
                     /locus_tag="VQU19_000275"
     CDS             13732..14994
                     /locus_tag="VQU19_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HET2479591.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LSAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(15081..15947)
                     /locus_tag="VQU19_000276"
     CDS             complement(15081..15947)
                     /locus_tag="VQU19_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II restriction endonuclease"
                     /protein_id="HET2479592.1"
                     /translation="MKQTRNFDEWLSTMTDTVADWTYYTDFPKVYKNVSSIKVALNIM
                     NSLIGSKNIQEDFLDLYQNYPEILKVVPLLIAKRLRDTIIVKDPIKDFYFDFSKRNYS
                     IEEYTMFLEKSGIFDLLQNHLVSNLVDYVTGVEVGMDTNGRKNRTGDAMENIVQSYLE
                     AEGYILGENLFKEIEQNEIEEIFSVDLSAITNDGNTVKRFDFVIKNEQVLYLIEVNFY
                     SGSGSKLNETARSYKMIAEEIKAIPNVEFMWITDGQGWYKAKNNLRETFDILPFLYNI
                     NDLEHNILKNLK"
     gene            complement(15934..16704)
                     /locus_tag="VQU19_000277"
     CDS             complement(15934..16704)
                     /locus_tag="VQU19_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HET2479593.1"
                     /translation="MTKPYYNKNKMILVHSDTFKFLSKMKPESMDMIFADPPYFLSNG
                     GISNSGGQVVSVDKGDWDKISSFEEKHEFNRKWIRLAKEVLKPNGTVWISGSLHNIYS
                     VGMALEQEGFKILNNITWQKTNPAPNLSCRYFTHSTETILWARKNDKKARHYYNYDLM
                     KELNDGKQMKDVWTGSLTKKVEKWAGKHPTQKPEYLLERIILASTKEGDYILDPFVGS
                     GTTGVVAKRLGRRFIGIDAEKEYLKIARKRLEAENETN"
     gene            complement(16730..17584)
                     /locus_tag="VQU19_000278"
     CDS             complement(16730..17584)
                     /locus_tag="VQU19_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HET2479594.1"
                     /translation="MKIKEIKKVTLQPFTKWTGGKRQLLPVIRELMPKTYNRYFEPFV
                     GGGALFFDLAPKDAVINDFNAELINCYQQIKDNPQELIEILKVHQEYNSKEYYLDLRS
                     ADRDERIDMMSEVQRAARILYMLRVNFNGLYRVNSKNQFNVPYGRYKNPKIVDEELIS
                     AISVYLNNNQLEIKVGDFEKAIVDVRTGDFVYFDPPYIPLSETSAFTSYTHEGFSFAD
                     QVRLRDAFKRLSDTGAYVMLSNSSSALVEELYKDFNIHYVEATRTNGAKSSSRGKISE
                     IIVTNYEK"
     gene            complement(17741..18145)
                     /locus_tag="VQU19_000279"
     CDS             complement(17741..18145)
                     /locus_tag="VQU19_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HET2479595.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERRVRI"
     gene            complement(18215..19696)
                     /locus_tag="VQU19_000280"
     CDS             complement(18215..19696)
                     /locus_tag="VQU19_000280"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HET2479596.1"
                     /translation="MTLVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWEAYAYSPE
                     QAIEDFYQLSQKNDYIKLKAIAKNIVYRVPSDYGELEITINLSKPEKDPKEIAVAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSADHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFARVLEDAGVYKQTEQGQTAFMRFVEHVGILLD"
     gene            complement(19715..20893)
                     /locus_tag="VQU19_000281"
     CDS             complement(19715..20893)
                     /locus_tag="VQU19_000281"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HET2479597.1"
                     /translation="MAQHLTTEALRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVFENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            21058..22065
                     /gene="galR"
                     /locus_tag="VQU19_000282"
     CDS             21058..22065
                     /gene="galR"
                     /locus_tag="VQU19_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HET2479598.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFRNYSQAKGIYHDELVFQGN
                     FTAQSGYDLMKEAIQNLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHDRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            complement(22111..23148)
                     /locus_tag="VQU19_000283"
     CDS             complement(22111..23148)
                     /locus_tag="VQU19_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HET2479599.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAVEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLQSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(23149..23502)
                     /locus_tag="VQU19_000284"
     CDS             complement(23149..23502)
                     /locus_tag="VQU19_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HET2479600.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            complement(23746..24636)
                     /locus_tag="VQU19_000285"
     CDS             complement(23746..24636)
                     /locus_tag="VQU19_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HET2479601.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            24769..25305
                     /locus_tag="VQU19_000286"
     CDS             24769..25305
                     /locus_tag="VQU19_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HET2479602.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNLPTSYLQHLVMSNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            complement(25472..26278)
                     /locus_tag="VQU19_000287"
     CDS             complement(25472..26278)
                     /locus_tag="VQU19_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HET2479603.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(26623..28143)
                     /locus_tag="VQU19_000288"
     CDS             complement(26623..28143)
                     /locus_tag="VQU19_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HET2479604.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPNLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLAALIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLVQKEKENLVIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGKTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMEPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
     gene            complement(28136..28864)
                     /locus_tag="VQU19_000289"
     CDS             complement(28136..28864)
                     /locus_tag="VQU19_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2479605.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKAPATDFVADLFGGSVHD"
     gene            complement(28879..29643)
                     /locus_tag="VQU19_000290"
     CDS             complement(28879..29643)
                     /locus_tag="VQU19_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HET2479606.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVVDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHDIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            complement(29647..30090)
                     /locus_tag="VQU19_000291"
     CDS             complement(29647..30090)
                     /locus_tag="VQU19_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET2479607.1"
                     /translation="MKDSHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKFQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            complement(30772..31068)
                     /locus_tag="VQU19_000292"
     CDS             complement(30772..31068)
                     /locus_tag="VQU19_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HET2479608.1"
                     /translation="MAEPNLESLIKDLYNHARHDLSEDLVAALLETAKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEELFKML"
     gene            complement(31090..32154)
                     /gene="pepA"
                     /locus_tag="VQU19_000293"
     CDS             complement(31090..32154)
                     /gene="pepA"
                     /locus_tag="VQU19_000293"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HET2479609.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            32555..33256
                     /gene="galE"
                     /locus_tag="VQU19_000294"
     CDS             32555..33256
                     /gene="galE"
                     /locus_tag="VQU19_000294"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HET2479610.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYKVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            33679..34638
                     /locus_tag="VQU19_000295"
     CDS             33679..34638
                     /locus_tag="VQU19_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2479611.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKEISESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLGFILLLWRGGRKDAD"
     gene            34628..35584
                     /locus_tag="VQU19_000296"
     CDS             34628..35584
                     /locus_tag="VQU19_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HET2479612.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLTLQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRSRQ"
     gene            35581..36333
                     /locus_tag="VQU19_000297"
     CDS             35581..36333
                     /locus_tag="VQU19_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2479613.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGS
                     TDQIMQADLLSQLYEIPITLADINDKKICIYS"
     gene            36429..37394
                     /locus_tag="VQU19_000298"
     CDS             36429..37394
                     /locus_tag="VQU19_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2479614.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEVSFESVKEINPAILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(37619..37861)
                     /gene="yidD"
                     /locus_tag="VQU19_000299"
     CDS             complement(37619..37861)
                     /gene="yidD"
                     /locus_tag="VQU19_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HET2479615.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(37861..38583)
                     /locus_tag="VQU19_000300"
     CDS             complement(37861..38583)
                     /locus_tag="VQU19_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HET2479616.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            complement(38570..39139)
                     /locus_tag="VQU19_000301"
     CDS             complement(38570..39139)
                     /locus_tag="VQU19_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HET2479617.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKSQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            complement(39158..39886)
                     /locus_tag="VQU19_000302"
     CDS             complement(39158..39886)
                     /locus_tag="VQU19_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HET2479618.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            complement(39886..40626)
                     /gene="xerD"
                     /locus_tag="VQU19_000303"
     CDS             complement(39886..40626)
                     /gene="xerD"
                     /locus_tag="VQU19_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HET2479619.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVT
                     IPTALLSELEPLMGQTYLFERGEKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            complement(40617..41078)
                     /locus_tag="VQU19_000304"
     CDS             complement(40617..41078)
                     /locus_tag="VQU19_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET2479620.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            complement(41075..41596)
                     /locus_tag="VQU19_000305"
     CDS             complement(41075..41596)
                     /locus_tag="VQU19_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HET2479621.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWLEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            complement(41572..42543)
                     /locus_tag="VQU19_000306"
     CDS             complement(41572..42543)
                     /locus_tag="VQU19_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HET2479622.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYKTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGKSSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            complement(42540..43334)
                     /gene="racE"
                     /locus_tag="VQU19_000307"
     CDS             complement(42540..43334)
                     /gene="racE"
                     /locus_tag="VQU19_000307"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HET2479623.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIYVEHVEL"
     gene            complement(43541..43789)
                     /locus_tag="VQU19_000308"
     CDS             complement(43541..43789)
                     /locus_tag="VQU19_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HET2479624.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            complement(43931..45556)
                     /gene="treC"
                     /locus_tag="VQU19_000309"
     CDS             complement(43931..45556)
                     /gene="treC"
                     /locus_tag="VQU19_000309"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HET2479625.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTGNGIGDFRGIIGKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCIGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
                     DLNWRNPNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKDINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            complement(45734..47701)
                     /gene="treP"
                     /locus_tag="VQU19_000310"
     CDS             complement(45734..47701)
                     /gene="treP"
                     /locus_tag="VQU19_000310"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HET2479626.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGNDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            47886..48596
                     /gene="treR"
                     /locus_tag="VQU19_000311"
     CDS             47886..48596
                     /gene="treR"
                     /locus_tag="VQU19_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HET2479627.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            complement(48629..49432)
                     /locus_tag="VQU19_000312"
     CDS             complement(48629..49432)
                     /locus_tag="VQU19_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000157668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2479628.1"
                     /translation="MASLLTLENIHKTFEAGTVNENHVLKGLDLEVEEGDFISVIGGN
                     GAGKSTLMNILAGNLSVDEGDLLLAGKSIKHLSVRKRAKDIARVFQDPKMGTASRLTI
                     EENMAIALRRGQKRGLGWGVKEKDRIQFQEALKELNIGLENRLKVDTQYLSGGQRQAL
                     TLVMAALVKLKLLLLDEHTAALDPKTSQMVMDLTQKIVEYHQWTTLMITHDMNHAIEY
                     GNRLIMLYQGKIVVDVKGEEKKHLTVEDLMHLFQKNSGQSLVSDELVLG"
     gene            complement(49445..49873)
                     /locus_tag="VQU19_000313"
     CDS             complement(49445..49873)
                     /locus_tag="VQU19_000313"
                     /inference="COORDINATES: protein motif:HMM:NF014684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2479629.1"
                     /translation="MKTEIGLVLRSTGDNIPMSEANGVNVNTMKIVGYMISTGLIALC
                     GSLFAQNDGFSDVTSGTGTIVVGLSSEVLIHDLTIGGRLLSIGIGAIVYRLIILNIYE
                     IPNLDQNLVRLFNAILLALVLFAPALQKRLKIRGLKLRNE"
     gene            complement(49882..50322)
                     /locus_tag="VQU19_000314"
     CDS             complement(49882..50322)
                     /locus_tag="VQU19_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2479630.1"
                     /translation="MNFVLSSLSEGLLWSIMAIGVYLTFRILDIADMTAEGAFPMGAA
                     IVVSQIQAGANPWLATLLALLAGMVAGLISGMLHTKMKIPALLTGIVTLTGLYSINIK
                     IMGSVPNLSLGDSATVFKQLASLGLTNEGAVFSLSLVCLLLVWF"
     gene            complement(50367..51272)
                     /locus_tag="VQU19_000315"
                     /pseudo
     CDS             complement(50367..51272)
                     /locus_tag="VQU19_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000512061.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
BASE COUNT        15175 a        11736 c         9477 g        15288 t
ORIGIN      
        1 attaaaaggt taagtaattt ttccaaaata cagcactcat atagacagta tcatcaatta
       61 tagccattgg gattttttga ttgccaattc catgtatctc tacacatgtc ttcaatcgat
      121 tttgttgtcc tccaatttaa ttccttatat gctttgtctg catttgcata ataagttgca
      181 acgtctcctg aacgtcttgg aactatttta taaggaatag ggatcttatt aacactttca
      241 aatgtattta caagttgtaa tacactagtg ccttctcccg agcctaggtt atagatataa
      301 acatctgttt tttcagatac tttttctaaa gcttttatat gtcctattgc taaatctact
      361 acttgaatct tttatctcat ttttcccttt ttcaaataag ttatctactc tatgatcagt
      421 tatttccatt tcgtttacta acatgacgca gtcacctagc atcatatact ccaacttttt
      481 ttctgaaagt ttagcaaata ttggtaagcg ataatatagt atattgaaac tagaatagta
      541 cacctctact tctaaaacat tgttagaaat cgatttgact gtcctgattg atttgtccta
      601 ttattatttc attttactat actctgttaa ttcatatgag tttaaaccga tttcatcttt
      661 aacctcgagt aaagcagttt caaatatttg tttaagagtt tttgattctt tacaattaac
      721 cgacaaactt tctgataaaa tatgtacaac ttctgagact gaataaccta tctcctcttt
      781 agaattatat aaatctgtag ctccaccaat aatccaaaaa tactgatttt gtgaacctac
      841 aatatcctca ttttctacgg aacttccttg tatcgaacaa attttattta tctttaccat
      901 aatacttcaa cccttttagt gtcaaaagta aaccaattcc tgtcactgtt aagaatagtt
      961 ccataatctt gttcgaacca gtctttggta atttttgttt tacatctact atttctttag
     1021 atttattaat atgattttca gtttctctgc catctccaac tattttatag tttacttctt
     1081 ctgtcttatt atcttgttta ttgtcgatct tgtcattcat ttgtctatta tctttacttg
     1141 agttaaactc tccgttcttc tggttactat caattacatt atttgaatta gattgttttt
     1201 cctctttgtt tttttctttt tcgtttttat cacttaaatt atttgttaca attttgtaaa
     1261 gcccattctc cgttacaata ttgaaattac catcgctatc acgtataaca gattctttcc
     1321 catttgcatt agatttgatg aatgatatat acttaccgga taaattataa aattggttat
     1381 ttaaaacggt tattttaccc tttgaatcct caataacaat tccttcttta ccaccgaata
     1441 tactattctc tgagactact aaattatcac taactcgtaa taattcaata tttggttgtt
     1501 ctgtttcctt agaattatta ttaattacat tttttgttac agtaatatct gatacttttc
     1561 ctaaatattc tgcactatct tttgcaactc gtatcgcttt tgttttagga tcggcaatat
     1621 taaatatatt ttcggcgata accacctgtt tatttaaatc taataggtct ttagtgtttt
     1681 tatagctata agcatttact aaagctgctc cgctttctcg ataatgtaca ctctctcctt
     1741 taactttctt atcaaagcga tttcctttga ttaatacatc agtgaatcct gtaaaacgta
     1801 cacctgcata catcatgtta tcaaaatgat tatttaaaat tttaatatta gaggggttct
     1861 gtgtcgacaa tgtttgatag tgtgtgccaa ttgctgttac taattcccca gatttatcac
     1921 ttttgccaaa ataggaattt tgaatagtca cattttcaga ttttttccca tcatcattca
     1981 aggcataagg aaaacctttt ctagttaatg gttcaatctg aatgctctcc ttacttatga
     2041 tttgcccatc cttcatcgtt ttgggtaagg cttgcccaag aaaacgagaa ttatcaacta
     2101 atacattttt cgaacctgca atttgaatag catgcccttg ataactatcc ttgaatgtta
     2161 cattttttat agttacgtta tttgaattcc caatagcaaa tgcacctgaa gaatttataa
     2221 gtggtagatt ttttgcttta gttccttctt cattcaaagc accgttcata tcaatcgtac
     2281 caccagaata actaatatct tctgttgggc cccattctac ttgcgcacca tcatccgtaa
     2341 ataaacctgt cataaaaaca atggaagggt gattcttaat atttatacca tttagaattg
     2401 tagctttctc attcaattct aagtgtgtat gactttttaa aaaaacaatt tcttttacta
     2461 aataagttcc ttcaggaaaa tatacatttc ctccacctag cccttgagct gcagcatcta
     2521 ttgcatcttg aattgcttgt cgatcatcat gaatcccatc acctaccgca ccataatctt
     2581 ttacacttaa agcagtatct tcaaattctt ttttgataat tctgtcactt ataacatctt
     2641 ccttataact cttattttca ttagtagata ttactgtaga ttcaactgtt ctgttgtcta
     2701 attgtgaatt ggaacgaata gtaccattag agctgatact attaacactt aacgaattat
     2761 ctaaaccatt agtggttgaa ttagaggcaa tcatttcagc agaacgattt tgattaacag
     2821 ttggtgaatt atctaaatca ttagtgattg cattagaaga ctcttttgta gccatcggtg
     2881 aagaactagt aacaacttca tccgataaaa taccttggct tcccaaaatt gaaattgcca
     2941 atagtaccga gcaagtcccc acctttaatt tacgaatact gaatacctca ttaggaacaa
     3001 aatatttcat cagaacctcc aattttttta ctatttttaa caattgatta ttacttttct
     3061 taaaatagat agaatgacac cgctgtcatt atctttatca tatattttcc aaattgaatt
     3121 gtcaaggaat aacacaagaa aatattaaaa tttatactct tcggaaatct cttcaaacta
     3181 ggtcagtgcc gccttgccct aagtctaggt tactgacttg gtcagttcta tagtagactg
     3241 aaactataat agtacacctc tacttctaaa acattgttag aaatcgattt gactgtcccg
     3301 atcgatttgt cctattctta tttcatttta ttatatctac aacctcaaag cagggttttg
     3361 agctatctat ggccaacttc ctagtttgct ctttagcctt ccattcaaaa gtgatgctat
     3421 ctttcttagc ttgaatataa aatatcccat ttactatatt taaatttgtt gatatgttgt
     3481 aaattataaa tgaaagaaca aatatcttgt catacaagca ttcgccaggg atatttacat
     3541 gaatatcgct catatggcgg attgaaacta aaacactaca atatatttct taaatagacc
     3601 ttctataaaa gctagattta acctcgataa aaatagatgc agtgcttcta aaatactgga
     3661 atagggcata taggtaatcg tagacaagtg ttttatagat tgtctcgcgg gagatctaat
     3721 gatgtatagc aagcatcact aaacatatag aatatttgtg ttattataat gtcaatatgc
     3781 tataaattct atcatgcaaa agaatgacta gaacatgaaa gacaggcaca aaactttgaa
     3841 caatattctg aaaacaaaaa aagacgcgag tttccacaat ctcactcatg gaaactcacg
     3901 tctttcaaaa aatagggtga attaaaaact agaacaagac actagatttt ctaaatgatg
     3961 tctagtaagg attctaaatg ctacaccaaa ttgctcacat cttatttcaa accacgggac
     4021 tcccacaaga aaggaaaatc ctataaaaat tctctctctg aggagagaga ggcctcaact
     4081 acaggtgtaa actattatca attgaaaaca acagttttta cactcaatta gactttttag
     4141 ggacaggatc actttcgctt gactgtagtt tgtcattttt ttgataaagt tagcactttt
     4201 tcagaaactg ttttgaaagt ctcaatgata tagtctactt cttcatcgct taatttagta
     4261 tgaagaggga gggtaatttc attctcaaag aaggcatagg ccttaggata gttcgtcata
     4321 tcaaatccaa gattcttata ggctgtcaag agaggaagcg gtttgtagtg aacattactt
     4381 gcaattcctg ctttagccaa ttcttggatg atgaggttgc gttcttctag gcttgctcct
     4441 tctacacggg tgatgtagag gtggcgtgaa gattcgacag tttcagtctt gtgtgccaaa
     4501 ggatggatgc gagaacctgc aaaaccacta tcatagcggt ccacaatgtc cttacggcgt
     4561 tgcaacaaac ttggatagcg gtccaattgt accaaaccaa gtgaagccat gatatcggtc
     4621 atgttgcact tataggctgg tgtaacgata tcgtattccc atgaccccag ttgcatcttg
     4681 gcaagagcat ccttagtttg cccgtgaagg gaaaggattt ggaattcctt gtacatctct
     4741 tcgtcatcaa tcactggatt ggctttccaa gtcgcacttc caccttctgc cgttgtaaag
     4801 ttcttaacgg catggaatga gaaggaagta aagtcagcga tagaaccaga aggttgtcct
     4861 ttataagtag atcccaaagc gtgggcacta tcagagacaa tgacaatacg gttaaaggcc
     4921 ttttgccact tgcttgaagc ggtaaagaag tcacgttttt tctccacgac ttggaacaaa
     4981 cggtcataat cgcaaacaat ccctgcgagc tctactggga taatcacctt agttttctca
     5041 gtgatagctt gctcaagcag gtcatagtcc atctcaaacg tatctgcttg gatatccacc
     5101 atgacagggg ttgctcccac gtgcgtaatg acactacatg aagccgtata ggttatggct
     5161 ggaacgatga cttcatcacc aggtcccact tcaaaaacgc gtaaaatcaa ctccagagcg
     5221 gctgtcgcag agttgagaca aacagtctta ggtgtctgtg tgtaaagaga caagcggcgc
     5281 tccagttctt ttgttttagg acctgttgtg atccaaccag aacgcagggt atccgctact
     5341 tcagcaattt ctgcttctgt gatatcaggc ggtgaaaatg gaatattgta atttggcatt
     5401 gatttgctcc ttttatctgt actcattctc ttatgactac tttattttag taccttaaac
     5461 acggtttgaa acatgatttt gatgtcccca aagaaactaa actctcggag ataggcgagg
     5521 ttatagcgca tcttttcagg aagaacatgc tccacatagg cctgatcaac tgacagacct
     5581 ttctctgtca tttgactgat gatggtgtcc tcatccttgt agttgatgct ggctggagag
     5641 gtaattcctg cttgcaagag caaggttgcc atcatttcag tgctatactg ctctgtataa
     5701 cgtggcactt caggtcgtgt accgacaaag gacatctcac ctttaaggac attgaccaac
     5761 tgaggcagtt cgtccaaacg gacacgtcgg atgaaatttc caaccttggt aatacggcta
     5821 tcgttagcag aagtcaccag atttcctttt ttatccgcat ccgtcaccat ggtacggaac
     5881 ttccaaatct tgaaccgacg gttgtactgg gtcacacgct cttgcttgta aatcactggc
     5941 cccttgctat ccaacttgat ccaaatgctc aagatgagaa agatgggaga ggtcagaacc
     6001 agtaagacca aggccaaaac ccagtccaag caacgcttga aaatcagcga acccttcctt
     6061 ttagagacaa gctggtagta agactcaacc tcgcttgatt tcatttccac aggcaagtct
     6121 tcccatttca gcatgctgtt ctcctttgtt tttattatac tatttgtcaa cactttttgt
     6181 caacactttt cattatacca caaaatggaa aaggcggtga aaaaaatctg taatttgaag
     6241 gatttccttc tagtactcaa tgaaaatcaa agtacagctt tgagattgca gataaagctg
     6301 acatggttta aagagatttt caaagagtat aggccatggc ccctgcctgc aaactataca
     6361 tcttgtgata ggttcctccc agagccaaga gttcctcatg ggttccactc tcgataatgc
     6421 gtcccttatc caagacatag atgcagttgg cgtcttgaat agtagaaagg cggtgagcta
     6481 tagcaatagt tgttcggccc tgtctcatct tcgccagaga agcttgaacc aagctttctg
     6541 tttcagagtc aatattggct gtcgcttcat ccaaaatcag gattttaggc tggctggcga
     6601 ctgttctagc aaaggcaaga agctggcgtt gcccagtaga gaagctcgaa ccacgctcgg
     6661 aaacagggga gtcgtacccc tgaggaagtt cttgaataaa ggaatctgca tccacaaagg
     6721 ctgccgcagc ctgaacctgc tcatcactga tttcttggta catggcgata ttggacttaa
     6781 tagttccatg atagaggaag ggttcctgca agaccaaacc gatgtttttt ctcagctctt
     6841 cttgactgaa atccctgata tccacatcat ccaagagaac tctccctgac tggaattcat
     6901 aaaagcgcat gaggacattg ataatagacg atttccctga acctgtatga cctacaaagg
     6961 caatggtttc acccttatta acagagaaag aaatgtcatc cagaatcgga tgtttaccgt
     7021 catatgagaa acacacatgt tcaaagcgga tattgccttc ttggactttg gcttgcccat
     7081 tttcttgaag aggttcatag gtcctctcgt ctaccagggc aaagacacga cctgcagaaa
     7141 ccatagacgt ttgcagtgtt gaaaagtttt gcgtcacctc aatcaaaggg tcaaagaggc
     7201 ggttgatgta ctggataaaa gcatacatgg tcccggccgt tatcccgata gaaagaccac
     7261 gatagccaaa ataggccatc aagacagcat aacctagaag tttcaacaaa ctcatggcag
     7321 gtctcaaaaa gagggcatcc aaggctacag aacggttggc atagaccaag tgctcttggt
     7381 tgatttcatc aaattctgcc tgcaggcgct tctcttgatt aaaggcctgg attattctga
     7441 ttccctcgat gttttcagcc agcttgctat tgatatctga caagagactt ctggttttct
     7501 caatgatttt cactgatttt ttccgataga gattgaccaa aaggaaaatc aaggggagaa
     7561 agagcaagac taatgctgtc aaacgaaaat ccaataccaa catggtataa agggttgtca
     7621 gaaagatgaa aactgctgag ataaagctag ataaaatccc agaaaacata tcactaatcg
     7681 tctcggtatc gttggtcaaa cgagaaacga tagaacctgc tggcgtcttg tcaaagtaag
     7741 acatgcccag tttctccata ttggcaaagg catcccgacg aatatcccta acaatactgt
     7801 aagacacgcg cgcaaagaga agattgccga catactgaac tacagtttgt aggatgtaga
     7861 gaccatagta gaccagcaaa acggtaacgg ctagttggtt aagattgctg agatactggt
     7921 cgataaagtg ggaagccacg aggggtatga cacttttaat gaccgtcgtc gctaggagaa
     7981 aactgagtgc caaaaaggtc aggagtctat aaggcttgag ataagacatc aagcgcttca
     8041 atacagccca ttgttcttgt ttattctgca tcttcttctc ctttcatttc taactgctga
     8101 gactggtagg tttgggcata ccagccatcc atcgctagca agtcttcgtg cctgcctcgt
     8161 tcgataattt gaccattttg tagaactaaa ataaaatctg catggacaac agcactgagg
     8221 cgatgggcag ttataatggt tgtcttgtcc tttcgcgtct ccttgagatt gtcgataatc
     8281 gcatactctg tcttggcatc tacggcggat aaggaatcat ccaaaatcaa gatatcaggg
     8341 tttaaaatca tagcccgact catagccaac cgttgctttt gaccaccaga aagactgact
     8401 cctttttcac caatcagcgt atcaaatcct tgaggcatgt ctacaatatc ttggtaaact
     8461 cgggctagct tagtagcttc ctcaacctct gaaaggggca agttaggatt gccaaagcgg
     8521 atattgtcta ggattgaagt cgcaaagaga aactggtcct gaggaacata gcccatgaga
     8581 ctgcgaagtt ctgtcaaacg atagtcccga atatcgtgac cgtttagata aatggcaccc
     8641 ttatccacat cgtattcacg caagaggagc ttgattaagg acgttttccc agagcctgtc
     8701 tgcccaacca agcccagtgt ttgccctttt gccaaactaa agtgaatatc cgtcagtgtt
     8761 tcctcatttt caaaagcaaa gctgtcaatg gcatactcca aacgcccatt ttcaatacca
     8821 tccagaggaa actcagggtc ttgtacagga gattcctgag acaaaagatt ttcaatccgc
     8881 tggtaagaaa ccttccctcg ctgagtagta ttaaagagga agccgatggc cataagaggc
     8941 cagaccagca tatccaaata gctgataaag gtgactagat taccaactgt aatctgccct
     9001 tcctgaacca tcaaggagcc aaccaaaagc gttaaaacat aggacgaacc aacaaacaag
     9061 agaaccatag ggtcaaagag actatcatat ttcatggttt gcaggttctt ttggaaggtt
     9121 aattcattga ctgcctgaaa agacttcaac tcgtctgcct gataaccgaa agacttggtc
     9181 actttgatac ctgatacgga ctcctgtacc ttgttattga gttcagaaaa agcagcttgg
     9241 gattcgccaa aggccttatg agtctttctc cctaggcgac tagtcgcata ggccatgaaa
     9301 ggtaggggga gaatggcaac aagagtcatc tgccatgaga tgctaaagag catggtcaac
     9361 aaagtcacca gagccgtgat agaggcatcc accgcagaca tgacaccgcc acctgctaaa
     9421 cgagtcaagg cattgatatc attggttgcg tgtgccatca gatcacccgt ccgataggtt
     9481 tgataaaagg ctggcgacat ttttgtgaaa tgcttaaaca agcgagaccg catgatctgt
     9541 cccaagcaat aagaggtccc aaggatatac atacgccaca catagcgcaa atagtacata
     9601 ccaaaggctg caagtagcaa gtaaaatagg ctaagaagga ggtcctgctg ggttaattgc
     9661 cccgatgtga tggcatcaat gactcgcccc ataaccatag gaggaatgag attgagaacg
     9721 gaaaccaaga ccagggccac aatcccgact agataacggt gtttttctaa cttgaaaaac
     9781 caccagagtt tttgaataat ggacataaaa tccctttctg attgcaaatg gaaacctgag
     9841 gccaatactc aatgaaaatc aaagagcaaa ctaggaaact agccgcaggc tgctcaaagc
     9901 actgctttga ggttgtagat agaactgacg aagtcagtaa cctacatacg gcaaggcgac
     9961 gttgacgcgg tttgaagaga ttttcgaaga gtacaagacc ccaggttttt cttattcata
    10021 agttacgact gtaacagcac ccttgtcata ttcagcaata aagatattgg ctacattgtc
    10081 atgcccttgt ttgctgaggt tatcaagcaa ccactcttcg ctacgaccaa tcgattccaa
    10141 gacgtctact tgaatcacac cgtcagtcac aactggatac ttaggatttt catctcccat
    10201 ttgcacaacg atgagttgcc cattttgctc ttgcacagct cgtttgactt gcttcatctg
    10261 gaaaatccct tggctacgaa gtttgagggc tacatccgat gcagacaaac caactgaacg
    10321 acaggcttat gggtcaatat tcccattttt gataaggaga gttggcttac catcaatcaa
    10381 acgtttcaca aagtgaacat tgttgttgag ctatttgaga gtcaagatca gtttgattaa
    10441 aatttcgata taattaagtg tcatttgttc acatccacca gttcaattgc gtctgtctta
    10501 tacaattcga ctttctctaa caggtacttg tctggctcac ttccgtttag ggcacgataa
    10561 tagcgatctc ccaccttgat aagtgcgcca tctgtgtttg tggaagtatt aacatggact
    10621 tctgacttgt ctactcccaa atctttggaa acaacctcga tgaaatgaag tgaagtttga
    10681 aatttattgt tagaaacttg attgttttga taagtcgtga tgctgaccaa aagcatagct
    10741 aaataaggcc agagctgaaa tcatgaccaa ctcacgaaat ttggttcctt ttttatcatg
    10801 gtatgccttg aaagcaaaaa aaactgtcac agctaataga acaatcccaa agccaaccat
    10861 gataccattt tgctgaccga tttggctgag tacatagtca taagagtaga atttcatgta
    10921 ttttcactcc ctttcataaa atcattctta attataaacg aaagagagta atttttcaaa
    10981 ccatacgttg gggaaataga tctttttttg gtataataaa atctataatc tgaatgaaaa
    11041 aggtaacttt atgaaactta tctcatggaa tattgattcc ctaaacgctg ccctaactag
    11101 tgactcagct cgtgccaaat tgtcccaaga agtcctacaa accttggtcg ctgaaaatgc
    11161 tgatatcatt gctatccaag aaaccaagct ttctgccaaa ggacctacaa agaaacacgt
    11221 ggaaatttta gaagaactct tcccaggcta cgaaaacacg tggcgctctt cccaagagcc
    11281 tgcccgtaaa ggctatgctg gaaccatgtt cctttataag aaagaactta cacccactat
    11341 cagcttccca gaaatcggtg ccccttctac catggacttg gaaggccgta tcatcactct
    11401 agaatttgat gcatttttcg taacccaagt ttacactcca aacgctggtg acggtctcaa
    11461 acgcttggaa gaacgccaag tctgggatgt caaatatgcg gagtatttgg ctgaactaga
    11521 caaagaaaaa ccagtccttg cgaccggtga ctacaacgta gcccacaatg aaatcgacct
    11581 tgcaaatcct gctagcaacc gccgttcacc tggatttact gacgaggaac gtgctggatt
    11641 taccaaccta ttggcaactg gatttactga taccttccgc catgttcatg gcgatgttcc
    11701 tgaacgctac acttggtggg cacaacgcag caaaacttct aaaatcaaca atacaggctg
    11761 gagaatcgac tactggctca caagtaaccg tatcgctgac aaggtcacta aatctgatat
    11821 gattgactca ggtgctcgcc aagaccatac accgattgtc ttggaaattg acttgtaagg
    11881 attttctata tggactacaa tgcggtcatt cccgagtttc ttgtatcgaa tatcgaacag
    11941 tcccggtcct tctactgtgg tttactgggt tttaggattg aataccaacg ttcagaagaa
    12001 aactttctct ttctcttgaa gagtgtcaac taatgttaga ggagggaaca aaggatcaac
    12061 tagctgaact gacctacccc tttggtcgtg gagtcaatct ctcctttggc ataaaggatg
    12121 ttccaaaact ctatcaaaaa gtgatggagg caaactatcc tatttatcgt cccttgacca
    12181 aaagaaagtt tcgtgtcagt gatccctata tctatcctca taaatttgca gttttggatc
    12241 cagatggcta ttttttaaga tttagcgagt agaataataa aaattgggaa aagtctttaa
    12301 aagttagaaa aaggcatatt gtcaggtgtc taaaaacttg atagtatgcc ttttatgatg
    12361 gaaaaatctt ctaatactct tcgaaaatct cttcaagcca cgtcaacgtc gccttaccgt
    12421 aggtatataa tactgactct gtcaattcta tccacaacct caaaacagtg ttttgaggtt
    12481 gtggatagct tcctagtttg ctctttgatt ttcatttagt ataaatgtta gcttacaatg
    12541 gagtttttgt tcaccctctc ttctgtttgt tcgtttttta aaccaaaaca ctaacaaaat
    12601 agttgatttc taaagttatt tagtgtaaaa taaaaacatt ggctcaagcc tatttaaaat
    12661 tgaatatcgt tttacttgtt tatgtcgtga attggcacga cgtttctaca aggtgccgga
    12721 acacctaaca ataagtaagt cagcagtgag atatggccgt ttttgccatg cctatttggg
    12781 ggacttactt agagattaag taggtctttt ttgaatattt ttaatatttc ccttaattag
    12841 tgcggacggg aggtgaaatt atcctgtgaa taatttcagg aatccaggga atttcatccc
    12901 taatttttga gcccctagct ctttcatttc taggcttagg ctaaaatagt tccccgaact
    12961 attttactct caaaaatccc gtcatagaca ataacaagat tattgtctat gataccacta
    13021 caacgggaaa tatttgataa gactcgcttc gctcgtaata gttttatcaa atatatagca
    13081 ttagcaaaag ggatcactat agaaacattt aaacaacaag taaattaact tttagacttt
    13141 aggaggtctt atgaaattat tagaagagcg catcctcaag gatgggcata tcttgggtga
    13201 taacatcctc aaggtagatt cctttttaac ccaccaagtt gactttagct tgatgcgaga
    13261 gattggtaag gtttttgcgg aaaaatttgc tgctgccggc attaccaagg tcgtaaccat
    13321 tgaagcgtcg ggtattgccc cagccgtttt tacagctgaa gccttaaacg ttcccatgat
    13381 tttcgccaaa aaagctaaga acatcaccat gaacgaaggc atcttaactg ctcaagtcta
    13441 ctcctttacc aagcaggtga ccagcaccgt ttctatcgct ggaaaattcc tctcaccaga
    13501 ggacaaggtt ttgattatcg acgatttcct tgctaatggc caagctgcta aaggcttgat
    13561 tcaaatcatc gaacaggccg gtgccacagt ccaagctatc ggtatcgtga ttgagaaatc
    13621 cttccaagat ggccgtgatt tgcttgaaaa agcaggctac cctgtcctat cacttgctcg
    13681 tttggatcgt tttgaaaatg gtcaggtcgt atttaaggag gcagatctct aatgcaaact
    13741 caagaaaaac actcgcaagc agccgttctt ggcttgcagc acttactagc catgtactca
    13801 ggatctatcc tggttcccat catgattgcg acagcccttg gctattcagc tgagcagttg
    13861 acctacctga tttctacaga tatcttcatg tgtggggtgg caaccttcct ccaactccaa
    13921 ctcaacaaat actttgggat tggactccca gtcgttcttg gagttgcatt ccagtcggtc
    13981 gctcccttga ttatgattgg gcaaagccat ggtagtggcg ctatgtttgg tgcccttatc
    14041 gcatctggga tttacgtggt tcttgtttca ggcatcttct caaaagtggc caatctcttc
    14101 ccctctatcg taacaggatc tgttattacc acgattggtt taaccttgat ccctgtcgct
    14161 attggaaata tgggaaataa cgttccagag ccaactggtc aaagtctctt gctttcagct
    14221 attactgttc tgattatcct cttgatcaac atctttacca aaggatttat caagtctatc
    14281 tctattttga ttggtctggt tgttggaact gccattgctg ctactatggg cttggtggac
    14341 ttctctcctg ttgcggtagc tccacttgtc catgtcccaa ctccactcta ctttgggatg
    14401 ccaacctttg aaatctcatc tattgtcatg atgtgtatca tcgcaacggt gtctatggtt
    14461 gagtcaactg gtgtttatct agccttgtct gatatcacaa aagatccaat cgacagcacg
    14521 cgccttcgca acggttaccg cgcagaaggt ttggccgtac ttctcggagg aatctttaac
    14581 accttccctt acaccggatt ttcacaaaac gttggtttgg ttaaattgtc aggcatcaaa
    14641 aaacgcctgc caatctacta cgcagctggt ttcctggttc tccttggact gcttcctaag
    14701 tttggtgccc ttgcccaaat cattccaagc tccgtcctcg gcggtgccat gctggtgatg
    14761 tttggttttg tatctattca agggatgcaa atcctagccc gagttgactt tgctaacaat
    14821 gaacacaact tccttatcgc agctgtttca atcgctgcag gtgtcggtct caacaacagt
    14881 aatctctttg tcagcatgcc gacagccttc caaatgttct tctcaaacgg aatcgtcgta
    14941 gccagcctac tcgccattgt cctcaatgcc gtattaaatc ataaaaagaa ataagaaaaa
    15001 gaggtgcgag cctctttttt gtttatcaca aattgattat aaatacaatc aatcccaatt
    15061 cccatctaat tgaattggac ctatttcaaa ttctttaaaa tattatgttc caaatcgtta
    15121 atattatata agaatggtaa aatatcaaat gtttctcgta aattattctt agccttatac
    15181 caaccttgtc catcagtaat ccacataaac tcaacattag gaatagcttt aatttcttca
    15241 gcaatcattt tgtaagatct agccgtctca tttaattttg aaccacttcc tgaataaaaa
    15301 ttaacctcaa tcagataaag cacttgttca ttttttatga caaaatcaaa acgtttcaca
    15361 gtattcccat cattcgtaat agcagataaa tcgacagaaa aaatttcctc tatttcattt
    15421 tgttcaatct ctttaaataa attctctcct aaaatatacc cttcagcttc aagataactt
    15481 tgaacaatat tttccatcgc atctccagtc cgatttttgc gcccattagt atccatacca
    15541 acctcaacac ctgtaacgta gtcaactaaa tttgatacta aatgattttg caataaatca
    15601 aatatacctg atttttccaa aaacatagta tattcttcaa tactatagtt tcgtttacta
    15661 aaatcaaaat agaaatcttt tatcggatcc ttaacaataa tcgtatctct caaacgttta
    15721 gcaataagta gaggcacaac tttcaaaatt tctggataat tttgatataa gtctaaaaaa
    15781 tcctcttgta tatttttact accaataaga ctattcataa tatttagagc aacttttata
    15841 ctagatacat ttttataaac cttgggaaaa tctgtataat aagtccagtc agctactgtg
    15901 tcggtcatcg ttgacaacca ctcatcaaaa tttctagttt gtttcatttt ctgcctccaa
    15961 cctcttcctt gcaattttta aatattcttt ttcagcatcg atacctataa atcttctacc
    16021 taaccgcttc gcaacaacac ccgtagtgcc actaccaaca aatgggtcta gaatatagtc
    16081 accctcttta gtagaggcta aaataatgcg ttctaacaaa tactctggtt tttgagttgg
    16141 atgtttccca gcccattttt caactttctt tgttaaagaa cccgtccaga catctttcat
    16201 ttgttttcca tcattcaatt ctttcattaa atcataattg tagtaatgac gagctttttt
    16261 atcatttttt ctggcccata aaatggtttc agtagaatgg gtaaaataac gacaagataa
    16321 attgggggca gggtttgttt tctgccaagt aatattattc agaattttaa aaccttcttg
    16381 ttctaatgcc attccaactg agtatatgtt gtgcaaacta cctgaaatcc ataccgtccc
    16441 attaggcttc agaacttctt ttgctaggcg aatccattta cgattaaact catgtttttc
    16501 ttcgaatgaa gaaattttat cccaatctcc tttatcaaca gaaacaactt gtcccccaga
    16561 attagatatt ccaccattac ttaaaaaata aggtggatca gcaaaaatca tatccatact
    16621 ttctggtttc atttttgata agaacttgaa cgtatctgaa tgaacaagaa tcatcttatt
    16681 tttattgtag tatggttttg tcataagaac acctccatac ttatattcgt tatttttcat
    16741 aatttgtgac tataatttca gaaatttttc ctcgacttga agattttgct ccattagttc
    16801 gggtagcttc aacataatgt atattaaaat ccttatacaa ctcctctact aaagcactag
    16861 aagaatttga taacataaca taagctcctg tatcactcaa tctcttaaag gcatctctta
    16921 atcttacttg atctgcaaaa gagaatccct catgagtata agacgtaaat gcactcgtct
    16981 cagacaatgg aatatatgga gggtcaaaat acacaaaatc tcctgttcga acatctacaa
    17041 ttgccttttc aaaatctccc actttaattt ctagttgatt gttatttaga taaactgaaa
    17101 tagcagatat caattcctca tcaacaattt taggattctt ataacgtcca tatggaacat
    17161 taaattggtt cttagaattc acacgatata gaccattaaa gttcactctc aacatatata
    17221 gaatacgtgc agctctttgt acttcggaca tcatatctat tctttcatca cgatctgcag
    17281 aacgtaaatc taaataatat tcttttgaat tatattcctg atgaactttc aaaatttcaa
    17341 tcaattcttg aggattgtcc ttaatttgtt gatagcaatt tattagttca gcgttaaaat
    17401 cattaataac tgcatcttta ggagccaaat caaaaaataa agctccacct ccaacaaaag
    17461 gttcgaaata cctgttatag gttttaggca ttaattctct aataacaggc aataattgtc
    17521 ttttaccacc tgtccatttc gtgaacggtt gtaaagtaac tttctttatt tcttttatct
    17581 tcatgctttt aattatacca tagaaattaa aacacaactc ttgtattttc taccacatta
    17641 ctaaattttc tattttagaa ttaaatcata tcaatataaa aaaatgagta aggcaaatct
    17701 tataaattcc aaaattcacc tcactctatt aaattactct ttatatcctt acccgtcttt
    17761 cctcagacct ttggcctgtg acaaacatag taaaggttgc tttgcagaca tttctgccct
    17821 cttgattggt gatatccaca tccatcacac aggttgtacg accttgatgg acacattctc
    17881 ctttaatggt caatacatcg tcgagttttc ctgccttaag gtagttgata gaggattgga
    17941 gtgtcacccc atcaagtccc agcgagataa ccaccaaacc actgatttgg tcacatagtg
    18001 tgaatagata gccaccatgg gcattgccat agtagttgag cgacgagttc actactttgg
    18061 tcgtcaccac aacgtgacca tctctcattt tttcaatttc gtaattttca aaggcagata
    18121 tagcgtcaaa atgaaagtct ttcatcgttt cctcctgata tttcaaatga cactatgata
    18181 ctacttttta taggactgtg caaggagaaa gctcctagtc tagtaaaatt ccgacatgtt
    18241 ccacaaagcg cataaaggct gtctgccctt gttctgtctg cttgtagact cctgcatcct
    18301 caagtacacg cgcaaagata gcacccacag agtccttgac gattgcaagg gctttttctt
    18361 tatccgttag gtctggatgt tgggatttga gttggtctgc ccactcctga tgataatcgg
    18421 caactgtaac agcttctcct acaagatagc tagcgacttg ctctacttct tctttcagac
    18481 gtggtggcaa gattgccaag cccatgacct caatcaagcc gatattttcc ttcttgatat
    18541 gttggacatc cttgtgggga tgatagatgc catcaggatg atctgctgaa gtctgattgt
    18601 ctcgcaagac caagtccaac tcaaactgtc catcacgctt acgcgctatt ggtgtgatgg
    18661 tgtgatgcgg tgtcccgtct gtctctgcta aaatctgcac actagaatct gaatactgac
    18721 gccattcctg gaaaatctta tcagctaagt taatcaaatc ctctttggaa tccgaagtca
    18781 agcgtaggac agacattggc cacttgataa ttccagcctt gacctgctca aaaccagcaa
    18841 atcggaaggt cttttgcaag ggagccaatt ccataggaaa tacgtgacgg cctccctgat
    18901 aatgatcatg agttagaata gagcccccca caatcggcag gtcggcatta gatccagcaa
    18961 aatatcctgg aaactgctct acgatagcca acagacgttc aaaactctga cgactaatgg
    19021 ccatgggacg atgctggcca tctaaaaaga tacaatgctc attaaagtaa gcatagggcg
    19081 aatactggaa accccattcc tgaccaacca tttcaaaacg gataatccgg tggttgctgc
    19141 gagctgggtg gttgacccga ccatggtaac cctcattctc taaacaaagt tgacactgag
    19201 gataattact agcttgcacc aacttggcta ccgcaatctc tttcggatcc ttttcaggct
    19261 tagagagatt gatggtaatt tcaagttctc cataatcaga tggaacacga taaacgatat
    19321 ttttagcaat ggccttgagt ttgatgtagt catttttctg actgagttga taaaaatcct
    19381 ctatcgcttg ctcaggagag taggcatagg cttcccagaa gtcacgattg acctgactcg
    19441 gacaaggagt caccaagtcc atcaattcag taccaaggat ttcacgcgca gtctgactat
    19501 cctcaatcgt ctctaatcga acggcttcct caactagctg gtccttgagg tcaatcaatt
    19561 tatccagatt ggtctcaact tccaaaacac cttctcccac tcgtgccaaa acacgattgg
    19621 tcaggtagat tcgatccatt tcctcaaatg aactttcaga aatgacatgt gttacaaatt
    19681 tatctactaa ggtcactata gagcctcctt ttgactagtc aaggacgcga gtgccacctg
    19741 caacttcagc gatatagaag cttggagcgt atccaactac ttcctcgtag tgtttgccta
    19801 cagcttcctt aaaggcctca acagtatctt tttgaaccaa ggcaatggca cagccaccaa
    19861 aaccagcccc tgtcatacga gcaccgagaa ctccttcttg tgcccaagct gtgtgaacaa
    19921 gagtatccaa ttccaaacca gttacttcat aatcatgctc cagagaaacg tgtgacgcat
    19981 tcatcaaacg accaaatgtt tccaaatcac ctgcttgaag ggctgcttga gctttaaggg
    20041 tacgttggtt ttcaaacaca gcatggcgag cacgtttcaa acgattttca tctttaatca
    20101 gatagctata ttggtcaacg gcccactcgt ccaattcacc cagggtctga atatccaagg
    20161 caacttgcaa ttcttccact gctttttcac actcagcacg acgttcattg tatttagagt
    20221 ccgccaattc acggcgtttg ttggtgttca tgataacaac gacattgtcc ttcaaatcaa
    20281 gtggcaccaa gtcgtattct aaagtattgg tatctaagta aatagcacgt tggtcagccc
    20341 ccataccaat agcaaattgg tccatgatac cagagttgac tccgataaag ttattttctg
    20401 tttgttttcc gattttaacc aaatcgagac gctctagttt taaatcaaag agatgctctg
    20461 ccacgactcc tgtcaagagc tccaaggatg ctgaagaaga caaaccagca ccatttggga
    20521 tattcccata aacataaaaa tcaaaacctt tgtcaatcac gtgcccagct tcttgcaaga
    20581 aatgaaggac accttttgga taattggtcc agttgtgctc tttttcaaac ttgaggtcag
    20641 cgagaggcac ttcgataatg cccttgtcct caaagttagc tgagtagaaa cgcaagactt
    20701 ggtcgtcacg cttacgagct gcaccgtaag ttcccaagga aatagcagca ggaaaaacgt
    20761 gcccaccgtt gtagtctgtg tgttcaccaa tcaaattaat gcggcctggt gaaaagaagg
    20821 tttggtctgc ttcttgacca aaaacagcaa gaaagtcttt gcgaagggct tcagtagtaa
    20881 gatgttgtgc catatgaatt ctcctttgac tgtccgttaa gccaccttaa cgtataatcg
    20941 ttttctttct attgtatcca aggaattttc caagatcaat cctttttact aaaattttag
    21001 taaaatatca gtaaaaagaa gaaaaacatg atatactaac ctaatcaagg aggatttatg
    21061 gctaccttaa aagacattgc acagctagcc tctgtctcta tcgcgaccgt atcccgcgtc
    21121 ctcaatcgcg accagagcct atctgttaca gaagaaacca gacaccgtat tttaaccgtt
    21181 gctgaagagc tgggctacac caagcacctc aagacaggcg agtcccacaa acccaagcaa
    21241 aagattgcca ttatccaatg ggtcagcgaa caaggggagc tggacgacct ctactactac
    21301 cagattcgcc taggaataga aaaaagagcc caagagttgg actatgatat cttgcgctat
    21361 tttaatgacc atccttttac cttaagcgag gaagtgattg ggattctctg cattggaaaa
    21421 tttagccgag ctcagatttc tgcctttgaa gaataccaaa aacccctggt ctttctagac
    21481 agtgatacac tttctctggg gcatacttgt attattacgg atttttacac tgccatgaaa
    21541 caggttgtcg attatttcct cagccaagga atggaccgta tcgggattct aacaggcctt
    21601 gaagaaacaa ctgaccaaga agaaatcatt caggataagc ggctggaaaa tttcagaaac
    21661 tacagtcaag caaaaggaat ctatcatgat gaactggtct ttcaaggaaa ctttactgcc
    21721 cagtctggct atgacttgat gaaggaagcc attcagaact tgggagacca actcccacca
    21781 gcatttttcg cagccagcga tagtttagct atcggtgccc ttcgtgccct ccaagaagct
    21841 ggaatcagcc taccagaccg tgtcagcctc atttccttta acgacaccag cctgaccaag
    21901 caggtttatc ctcccctctc cagcatcaca gtttatactg aagaaatggg gcgagcaggt
    21961 atggatattc ttaacaagga agtcctccac gatcgcaaaa ttcctagcct gaccatgctg
    22021 ggaaccagac tgacattaag agaaagtacc ctaaatcaag aataggataa cataaaaaac
    22081 gaatagagtt ctaaaactcc tattcgtttt ttattcgatt acaatcatag acttaatggt
    22141 cttacgttca tccatatctt tgtaggcttg gtcgatatct tccagtttat aacttgaagt
    22201 aaagacgcga cctggattga tatcaccatc aaggacggct tttagtaaaa attgcttatc
    22261 gtatgttgta gcagaagctg ccccacctgc tacagagata ttttgcataa atgtcgaacc
    22321 aagagcacga ttattatagt gtgggactcc tacaaagccc atacgccctc cattatgaag
    22381 aacacctagc gcctgttcta tagcagcctc cgtaccaaca cattcaagtg ctgcgtctgc
    22441 tcctccaccg aggatttcac gcaccttggt aattccttct tgaccacgtt ctgcaacaac
    22501 agctgtcgca cctgactcca tagccatctt ttgacggtct tcatgacggc tcataaggat
    22561 aatttgtgat gctccacgca tcttagccgc gatgacagca cattgaccaa cagccccatc
    22621 accgataaca acaaccttgt cccctttttg aacatttgca acacgcgccg catgatagcc
    22681 tgtcggcatg acatctgcaa gagtcaaaag ggactggagc atcccttctg tatagtcaga
    22741 aggttgacca gggattttaa ccagcgccca gtttgcatag tggaagcgaa tatattctgc
    22801 ctgaaaatca ccccccaaat tattgccaat atgattgtcg caagaaccgt caaatccagc
    22861 aagacaggca tcacactcac cacatccatg tgtaaaaggg acaatcacaa aatcacctgg
    22921 tttcaccgtc gtaatggctt ccacagcttc ttcaacaatc ccaatcgctt cgtgtccact
    22981 atttttgtgt ccagctttcg tttctggatt acggtacctc cataaatctg aaccacaaac
    23041 gcacgcacga accacacgaa taatcacatc atccgcttct attatttgcg gacgttcaat
    23101 gctagcaagt ccaacctgac ctgcctttgt atatactgct gatttcattt aaaattttcc
    23161 ttccttataa agtttaattt tgagatttaa acgatttaaa gctgtctgta gctgagacaa
    23221 gcgctcctct aatttttgct tttcctcttc taaaatacca agcctctcct ctctcgtttc
    23281 atctcccttt tggtagagcg acatatagtc aactaaacta tctacagaga cacccgccga
    23341 acgaaaacac ttaataaatt ccagcgcttc gatatcctga tcttgaaaat cacgaatccc
    23401 agtagcagta cgagtaatcg gtggcacaag accaacccgt tcataatacc gaatcgtatc
    23461 cgctgaaatt cccaacaaat cactggcaga tttaatattc acacgctaac ctcctctcat
    23521 ttcattcact gaattcacgc tattctaact cacttatctt attatataac tttgagttga
    23581 ctccaagtca agcattttgt atctaatcga aaaattttta tcattaacaa tcatatatct
    23641 ggagtttata caatgctctt ctcttaccaa tttttgaaat atttaaataa taaagaaatt
    23701 actctattcc aaataagata gtacccaagt atttttcact tttttctaat gttgatgctc
    23761 ataactccgt tccaagtcac acacctttcg cttatgggtt tggtgagttt ctaggtcagc
    23821 atcaatttca atggtaatat tttgaaaacc acaatctttt aggaaaattc gaatagactc
    23881 tttacaagtt tccatatgtt ccatttcttt tagacaaaca tggacaatgg catttttttc
    23941 caaagcatcc atagtccaga gattaagctg attaaggctg gccacattgt ccaatcgctc
    24001 caggccactc tttacttgct tgatatcaag accttctggc acagcatcca agaaaatctt
    24061 gagtgtagac caaaaacgtg gaagggcttt tgaaagaata aagaaagaaa tgacaaggga
    24121 caaaagagga tctaggatat accagtccgt aaatcgaaga acaatcgcca tcaggataac
    24181 agctacccac cctagcgtat cttccagaaa atgcagactc agaatagact cattctttgt
    24241 ctttccctta ccaaccacca gactcgctaa cagattgata gtaatcgcaa taattcctaa
    24301 ccagagaatc ccctcatcat tgactggttg cggatgcaaa atcttcgtga cattttccaa
    24361 aatgactaga acagagcccg ttacgagaat cacagctgtt accaaggctc ctagcaggct
    24421 aaaccgctta tagcccaagg tgtactgatt gtcttcttca cgattggaga ttgtttctag
    24481 aaaagctgat attccaattg caatcgcatc tcccaagtca tgcacagagt cagcaagaac
    24541 agcgctagaa ccaaatactc cacctgcaat aaactcaaca atggcataag tcaaatttaa
    24601 gaaaaaagcc acccaaacag catattttgc cttcatattt ctcattcctt tgttataata
    24661 gatttatgaa caccttgttc attatcatta tccactaaaa ctcaaagaaa ggatagaagc
    24721 aaaacgtcag ctttattcag ttctgaacaa tttgccttaa gtgtccatat gactaacatt
    24781 gaccgccgta tcagcaaaac caaaaaagcc atctatcaag cttttataca acttttgaat
    24841 gctaagggct acgaggccac tactgttcag gatatcattg atctcgcaga tgtgggacga
    24901 tccacctttt actgtcacta tgagagtaag gagcttcttc tggaccagct ctgccgctac
    24961 ctcttccatc atctttttga aagagagcaa gccatttcaa ccgaggacta cctcgcccac
    25021 ctctttctcc attttcataa aaaccaagac catatcacca gtctgctatt ttccaaaaat
    25081 gactacttcc tccgtcaact ccataaagag ctagaacacc atgtctattc cgtgctagct
    25141 gataatttaa aagaagccca ccctaatctg cctacttctt acctccaaca cttggtcatg
    25201 tccaacttta tcgagacatt gacctggtgg ctcaaaaaag gtcaagattt cacagaccag
    25261 gaagttgtcc aattttatct agaccttctc attcctaaaa attgaatata gagtaaagct
    25321 tcagttgtct tatttctagg ttactgagtt ttttatcttt tcaacaacaa aagaggaccc
    25381 gccgatcctc tttttcatac tataaatcct tgattatcaa ctatatctgt tttaatcgaa
    25441 atctcaaaac agcactttca aacatctttt cctagttaag taaatcagta ttctgcttag
    25501 ctgccttgct ccattgatac caaccaacta gactgttaat gagataaatt agatatttcc
    25561 cttgaatttg caggctttct ccccaccaga gatagattga aaagacattg gtagccgccc
    25621 agaatatcca ctgttcacgg taaacagctg tcatgaggat ttgccctacc ccattggttg
    25681 catctgtgat tgaatcacga tagggacgat tggcaccaat agactgataa atgaagccaa
    25741 aggccaacca ccaaagcaca ctaatggaaa gatactttgt ccagcccttg ccgtccagtt
    25801 tacgcgcgac aaactcctgc ttttccttct taaactgtgc ctgataaatc caaactagaa
    25861 gtccaattgg ctgcatgact gtgaagtaaa gtgtcgtcag cacctcacca taaaagcctt
    25921 tctgtagggc caaaataagg taaataacag agttaatcaa gccaaaaaga taattacttg
    25981 ctcgaccttc cgatacaaag attacacaga taatccctgt caagctacaa atcatcccaa
    26041 tccagtcaac aatacgatgt tcgtaaacca actccagcca gagaggaaaa cttcctaaaa
    26101 ccagcaaata aatccactgg gcaaaactac gatgggcaaa gaggtcatcc cagatagcct
    26161 tcatagttcc tgaaaatcct aaatcagcca tagccgcaac catacgacgg taaccacctg
    26221 acatttcacc tagggttgtt ttgatatttt caattttctt ttgcaaataa gtatgcatca
    26281 tttctccttt tgtttttaaa gagccgtgtc tggatagact ttcggacgca acgctctatt
    26341 agataatgaa ctgcctatac acaagatttc taaccttagt cgacatgagc tgaaacctct
    26401 tatttgttaa gtagttcaca aaatattata cacctatttt atgaatagtc aactgtcttt
    26461 acagtaaaat tttagaaaat catgaaaatt ttctctttct ttccatttta agtgacattc
    26521 agtcattctc acatcaaaaa agcccagacg aaattgtctg agcattcttt tatctagtcg
    26581 tttaaggaag ttgagttcag tatgtttaaa gtctctgtcc catcatttct tcaacaaacc
    26641 ttgttcttgg agaaactcct tggctacttg ctttgctgac ttgccttcaa caccgacttg
    26701 gtagttgagc tggctcatct ggctttctgt aatcttacca gccaatgtat taagaactct
    26761 ttccaactct gggtgtttct tgagaagagc ttctttcatg agtggagccc cttgataagg
    26821 tgggaagagt tgcttgtcat cttccaagac ctgtaaatca taacgctcca attccgcatc
    26881 agtcgaatag gcatccgtga tttgaatatc ccctgactga atagcctgat agcgaagggc
    26941 tggctccatg gtcgctacat tgagattgag accatacatt gattgcaagc ccttatttcc
    27001 atcttcacgg tcgttaaact cgagtgtaaa acctgccttc aactgccctt ccactttttt
    27061 caagtctgaa atggtcttca agccatattc ttgagcaatc tttttcggaa cagctacagc
    27121 ataggtgttt tgataagaca tgggtttgag ataggctaga tgatcctgct tagcaatgcc
    27181 atcacgcgcc acctgataaa cctgttctgg ttcatgactc accttgggtg atggttgaag
    27241 caaactttca gtcaccgtac cagtaaattc aggatagatg tcaatatcgc cttttttcag
    27301 agcttcataa aggaagcttg tcttcccaaa attcggttta acagtcgcag tcatgctggt
    27361 attttcttca atcagcaact tatacatatt ggccaaaatt tctggttctg gacctatttt
    27421 cccagcaata accaagtttt ccttctcttt ttgaaccaaa agagctggac tataagacag
    27481 acccagtaat aaagccacca aggcaaaacc tgagaaaatc gtccgtaatt ttgctttttc
    27541 catcactttt agtaggaagt taaaggcaat ggctagcact gcagaagaaa gtgccccaat
    27601 caaaatcaaa ctggcattat tacggtcaat tcccaaaaga ataaaggaac ctagtccccc
    27661 tgcaccaatc aaggccgcca aggttgccgt accgataatc aaaacagctg ccgtccgaat
    27721 cccagacatg ataacaggca tggcgagtgg aatttcaaat ttcttgagac gttcccatct
    27781 ggtcatccca aaggcaatcc cagcctcttg caggttcgga tcaattccct tcagcccagt
    27841 gatagtattt tgcaaaatag ggaaaatcgc ataaatcact agagctgtca aagccggcaa
    27901 ggtcccaatt cccatcaaag ggataaagag ccccaacaag gccagagacg ggatggtctg
    27961 gaaaatacct gcaatctgca agacccagtc ggccagcttc tcatgatagc gaagaaaaac
    28021 agccaaggga atcgcaagca aaatagctag taacaaggtc aaaagcgaca actgcaaatg
    28081 ttgagataga gctgtcaacc aatcactaaa acgatcctga aaagttgcaa ttaaattagt
    28141 catgaacact acctccaaac aagtctgcta caaagtctgt tgcaggcgct tttaaaattg
    28201 tctcgggatt cgctacctgg cgaatttctc catcctgcaa gacagcaata cggtccgcca
    28261 acttcaaggc ttcatccgta tcatgggtta caaaaatcgt tgtcatccca aactctttat
    28321 gcaattcttt tgtcagaacc tgcaactgtt ttctcgaaat agcatccaag gccgaaaagg
    28381 gttcatccat gaggaaaatc ttgggctgac caatcatagc tcggacaata ccgacccgtt
    28441 gctgttctcc accagataat tcactaggta agcgatgccc atactcggct actggtaaac
    28501 caaccttagc caaaagctct tctgttttct tcgtaatttc ttccttgctc caccccttca
    28561 tttcaggaat gagagcaata ttttccgcaa ctgttagatt tggaaaaaga gcaatagcct
    28621 gtaaaacata accagtagaa agacgaagtt cacgctcatc atagtctttg atgcgcttcc
    28681 catccatata aatatttcca tcagttggtt ccaaaagacg gttaatcatc ttgagcatgg
    28741 tcgtcttacc tgacccagaa ggccctacta aaaccataaa ttccccatcc tcaatctgta
    28801 agttgacatc tctcaagaca tccttttctg tgtagcgcag tgctacattt ttgtattcaa
    28861 tcattctttg tcctcaattt aaaacttccc tcgattggtc aagtcttcta ccttaggcat
    28921 aacttcctta ttatcccaat gctccacaat tttcccgttc tctaaacgga agatatcgta
    28981 ctgggcataa gcaacgccat caatctgagt ctgaccatag ctaaccacat agtttccttg
    29041 tcctaagagt tggaaaacaa agtcaaaagt gacactatat tcagccacat agtttttata
    29101 agcagcactt ccttgtccaa tatcatgatt atgctgaatc aaatcgtctg ccacataatc
    29161 actccactgc tctagctccc cattttggaa aatttctgtc aagaaacggc gaaccagctt
    29221 tttattttct gctttcttgt ccaaatcctt gatttcaaaa tctccaaaaa tttgatctag
    29281 ttggtcattt tcaggtgttc gatagtagtc aacgacatcc caatgctcaa caatacgacc
    29341 attctcatcc gcacggaaag tatccgtcgt cacccattga gcttctccac cattcagata
    29401 ttgatgaaca tgaacaaaga ccagattgcc atcctcaatg gtgcggacaa tcttaatctg
    29461 acgctctgga tgacgctcaa agaaatctgc aaagaaggct gcaaatcctt ctttcccgtc
    29521 aggaacacct gtcgaatgtt ggatataggt atcccctaca gactgggctt gagcctcagc
    29581 aactcgcccg tcttgaatgg catggatgta taggttgtga gcatttttca cttgttgtga
    29641 catattctaa acctcatttc ccttctcttt cagattcgcc aaaattcttt cttgaaaacc
    29701 ttcaaattgg tgaatttctt cctctgaaaa tcctttgtaa aagatagtat ccaatttctg
    29761 actgacacga tgccccactt ctttctggaa cttgcctaac tccgttaaaa ctaaatactt
    29821 cttacgcttg tcttttccac acggactaac aattacaagc ttttgttcct ctagcttttt
    29881 tatcatagtc gtcagcgtat tattcgcaag cccagtcgca agcgcgatat ctgtcgcagt
    29941 tgcgcagcca gtttcactat tccataaaac cgctaaaatc ttgccctgtt cacccctata
    30001 aagagcctca ggatcttgac tcagtaactt ttgaaaaatc cgcccattca acaaacgaat
    30061 atgatgggct agcaaatgac tatctttcat aacacctcca atttatttcg atatcgaaat
    30121 gaataaaata attgtaacac tcatcgttct aactgtcaac tatttcgatt tggaaataat
    30181 ttttgataat tatccacacc accatactcc ggctcaacta acttttaacg agagtttcta
    30241 aactccttcg tcctccagtc tacaaaagcc ttccattcgt actatcctat attttatgag
    30301 gggacacatt tttcctatca gaccatttat tttaaagata gaagtaaatc ataattgctt
    30361 ccatctgttc ttttatagta tattgaagtt agactagagc actgtatctt ctaaaacatt
    30421 gatagaaagc gatttgaatt tcccaatcaa tttgttcgta tttatagcat tttgaaacta
    30481 gaataggaca ccatgactgc taaaagattt ctataaattc atttgatttt cctaatcaat
    30541 ttgttcatat cttatttcat tccgctataa tttcacctta ccctatcttt ttcgtagcac
    30601 ccttcaaaca gcctatcccc taccgtttga cgattcctca cttcgctcca cttccattac
    30661 agaagtttct tcactactat gggctcggct gacttctcat gattccttgt tactactatt
    30721 tgaacgctca cgagatagat cttacaaaaa atgctttgat ccacaatgga atcaaagcat
    30781 tttaaagagt tcctcataca taagcgcaga agtcgcagtt cctctgtact tggcttcttc
    30841 tcttttgata aagcgagcca agttgagcaa ctcaggtgct ggatgtttgg gatttaggag
    30901 caattcacga ttgaccaggc ctgagagacg aactgcctgc aattgctcat ttgtagtagg
    30961 cagtttttta gcagtctcta ggagagcagc aactaaatct tcactcaaat catgtcgagc
    31021 atgattgtaa agatctttta taaggctttc taggtttggt tctgccatcc ctaccacctc
    31081 ccttatggtt taataatgtt taatcaaatc aaccgttgaa cgatccaatt tcttcaccaa
    31141 ggcttgtaag aaagcttgcg cttctaggaa gtcatccatt gcatagaggg tttggtgaga
    31201 atggatataa cgagcgcaga caccgatagt tgttgatggg acaccaccat ttttcagatg
    31261 agctgcacct gcatctgttc cgcctttacc acagtagtat tggtacttga taccagcttc
    31321 ttcagccgtt gtcaaaagaa aatccttcat ccctgggaga agcaagtgac ctggatcata
    31381 gaaacgaatc aaggttccat ctccaatctt gccttgacca ccgtagacat cacctgctgg
    31441 tgagcaatca actgcgagga agacttctgg gtcaaacttg gttgtagagg tatgagcgcc
    31501 acgcagacca acttcttctt ggacgttaga acccagatag agttcattgc cgagtttttg
    31561 acctgataaa gcttcagcta gctcgcttac catgaggaca ccgtagcggt tatcccaagc
    31621 ttttgagatg atattttttt cattggctgt caaaattgca gaactatctg gtacgatggt
    31681 atcaccagga cggatgccaa aactttctgc ctcagccttg tccgcaaaac caccatcaaa
    31741 aacgatatcg gcaatggctg gcatggttgg tccccccttt ccacgagtca aatgcggagg
    31801 aacagaacct gaaatcacag gaatttcatg accatcacga gtcaagagtt tgaaacgttg
    31861 gctgctaacc accatggggt tccagccacc gatttctacg acacggaagg taccatctgg
    31921 cttgatttcg ctgaccataa aaccaacttc gtccatatga gaagcgacca agacgcgcgg
    31981 tgcatccaca gcttctgaat gtttgatacc aaaaatacca cccaagccat ctgtcaccac
    32041 ttcatccaca tgcggtgtca acttttcacg aagataagca cggacaggcg cttcatgacc
    32101 tgagactgca gcaagttctg ttacttcttt aatttttgaa aataatgttg tcatttcagt
    32161 tccttctttc tttcatccat tttaccactt tttataggag aaggatagtg ggaaggtgga
    32221 tttctaagtt agtatcttag tcctgctcta tcttagaaaa ggatagtatt ctcttgcatg
    32281 tagtgcaaaa tctagtaaac attccaaaat taactcgaat atttatttcc aaacaaaaaa
    32341 acaatacacc atcaaagttg tttgtatttt tcatgaaatt tacagaaaat agttgacttc
    32401 cctttcttct ttctttaaat atatagttgg ttgagtttgg aatagtacgc tgtagctgct
    32461 gaaacatttc tagaaattaa tttgactttc ctaatagagt tgttcatatc ttatttcaat
    32521 ttactatagt acaaaactag aaaaggaaaa aatcatgacc aaaacaattc ttgttacagg
    32581 tgggactagc tacattggct cccataccgt taaagctctt ttaaatgctg gctataaggt
    32641 gcatgtcctc gataatctct ccacaggaaa tcgagcggct gtggatagtc gtgctagctt
    32701 taaagaactg gatgtttatg atgctagcgc cttaaaggct tacttagaag aaaatcagat
    32761 tgatgctgtc ctccattgtg caggtgaaat tgttgtgagc gaaagtattg aaaatccaag
    32821 taaatacttc actgccaacg ttgctggtat gaaccaagtt ctcaaagtct tatctgaagt
    32881 tggcattcaa aaaatcatgt tctcttcgac tgcttctctc tatggaaata actgtattga
    32941 caagccagtg actgaagata ccctgctcga ccctgtcaac ccttatgcag agacaaaact
    33001 gatgggcgaa cgaatgattt actggatggc caatcgctac gactggaaat atgttatttt
    33061 ccgttacttt aatgttgctg gggctgaaat ggatgcttca aacggtctgc gtgtgaaaaa
    33121 tccaactcac atcattccaa atatcaacaa gaccgcattg ggacaaaatg atagcttaaa
    33181 aatatttgga gatgactacg atacacgtga cggttcatgt attcgagatt acatttatgt
    33241 cttggacctt gcataggctc atgttaaagg aatgaactac ctatttcaag aagacagttc
    33301 ttctcaaatc tttaacttag gaactaaaaa aggctatact atcaaagaaa tctttaaaac
    33361 tgctgaagaa ttactaaatt aaaaaatccc acacgagatt gttgctcgac gtgctagtga
    33421 cccagccagt gtcctagcag atgcttcaaa agctaaacaa tatcttgatt ggacggctag
    33481 ctactccctc gaagatatta ttttatcaga ttaaggtaaa aacattttag aataggataa
    33541 caaaggagaa agtcttgttg ctctctcctt gttgtattta ttaaattgtc agaaatttta
    33601 ttgacagatt agaaaaataa tgttacattt atatccgcag atatctttcg ataccaaatc
    33661 tacatgaaag gacggggtat gaaactttct cattatttaa ttggcttact tctactccta
    33721 gtctttctct ctattagcat tgggaccagt gatttttcat ggggaaagct atttgatttc
    33781 gaccagcaga catggctcct ctttcaagag tcccgtctcc caagaactat cagtattctc
    33841 ctgactgcct ctagtatgag tatggcaggc cttctcatgc agactattac ccaaaatcag
    33901 tttgctgcac cgagtacagt tggaacgact gaagccgcca aactgggaat ggtgctgagc
    33961 ctttttgtct ttccatcggc tagtctgacc caaaagatgc tcttcgcttt tgtttcatcc
    34021 atcgtattca ccctcttctt cctagccttt atgaccattt ttactgtaaa ggaaaggtgg
    34081 atgttgcctc tgattgggat catctatagc gggattatcg gctcagtcac agaagttatc
    34141 gcctatcgtt tcaatctggt tcagagtatg actgcctgga cccagggctc cttctccatg
    34201 attcagaccc atcagtatga gtggctcttc ttaggcctca tcatcctgat aaccgtttgg
    34261 aaattatccc aaaccttcac catcatgaat ctggggaaag aaatcagcga gagtttgggg
    34321 atttcctact ccctacttga aaaactggcc ctctttctgg tggcgctaac gacaagcgtc
    34381 accatgatta ccgtgggtgg cctaccattt ctcggagtta tcgttcccaa tcttgttcgc
    34441 aagcgctatg gagataatct aagtcaaacc aaactcatgg tcgcactggt tggtgccaat
    34501 ctagttctgg cttgcgatat cctatcccga gttctgatta ggccctatga gttgtctgtc
    34561 agtctcttgc taggaatcat cggtagtctc ggctttatcc tacttctctg gagaggggga
    34621 cgaaaagatg cagactaaaa gcaaacatac caagctcttc tggattctca ttattcttgc
    34681 catcggagct tgtcttctct acttttggcc catcactcac ttgtcagcct ttgcttggaa
    34741 gttgcgttcc caaaagatca tcgtttatct cttggtagcc atcgcgactg ggatttcgac
    34801 cattagtttt caaaccctga cggaaaatcg cttcctgacg cctagtattt tgggaattga
    34861 atccttctac gtcctactac aaaccctact actggttttt gaaagcaagt ttcttcaact
    34921 tggcaaatcc cctatcttag aattcctagt cttacttctt gtccagtccc tcttctttct
    34981 caccttacaa ggttacttga agacactgat gaagcaagac ctggtcttca tcctgctgat
    35041 ctgtctagcg ctcagaagtc tctttcgaaa tatcagcacc ttccttcaag tcctaatgga
    35101 tccaaacgaa tacgataaac tgcaaaatag tctttttgcc tcctttcaac atctcaacac
    35161 ttccatccta gccatcggtt ctctgatcat cctcgctttg acaatctttt tctttcgaaa
    35221 agcagtcgtt ctagatgtct tgcacctgca aagagaaacg gctcagatat tgggactcga
    35281 tgttgaaaaa gaacagaaag agctcctctg gggaatcgtg cttttgacct caacggccac
    35341 tgccttggta ggacctatgg ccttcttcgg ctttatgctg gccaacctca cctacctgat
    35401 tgtcaaagac tatcagcaca agttactctt tatagtggcc attctggttg gatttattag
    35461 cttaaccttg gggcaagcct tgattgaacg agtctttgca ctggaaattc gtatcagtat
    35521 gatcattgag agtgtgggtg gcttcttatt ctttatctta ctatatagga ggtctcgtca
    35581 gtgaaactgg aaaacattga caaatccatt caaaaacagg atattttgca aggcatttcg
    35641 cttgaagtca gtcctcaaaa actgacagcc tttattggtc caaatggtgc tggaaaatcg
    35701 actctcctct ccatcatgag cagactaacc aagaaagatc agggagttct cagtatcaaa
    35761 ggacgtgaaa tcgagagctg gaattcgcaa gaactggccc aagaactaac catcctaaaa
    35821 cagaaaatca attaccaagc caaattgact gttgaagaac tggtcagttt tggacgtttt
    35881 ccctacagcc gaggtcgact tagatcagaa gactgggaaa aaatccgaga aactctgaac
    35941 tatttggaac tgaccaactt aaaagaccgc tacatcaata gcctgtcagg ggggcaactc
    36001 cagcgcgtct ttatcgctat ggtactggcc caggatacgg actttatctt gctggacgaa
    36061 ccactcaaca atctcgatat caagcaaagc gtcagcatga tgcagattct tcgacgactg
    36121 gtggaggaac tcggcaagac cattatcatc gtcctccacg atatcaacat ggccagtcag
    36181 tatgcagatg aaattgtcgc cttcaaggac ggccaggtct ttagcaaggg aagcaccgat
    36241 caaatcatgc aggctgacct gctcagtcaa ctttatgaga ttcccatcac gctagctgat
    36301 atcaatgaca aaaagatctg tatctatagc tagtaacata aaagctcaag ttagagaacc
    36361 ttcagtctct tagtcaataa gattaagaga ctccctaaat cgttatcaca ttttaaaaag
    36421 gagaaattat gaaaacatcc cttaaacttt atttcactgc cctagtggcc agcttcttgc
    36481 tcctacttgg tgcatgtagt acaaactcaa gcactagtca gacagagacc agtagctctg
    36541 ctccaacaga ggtaaccatt aaaagttcac tggacgaggt caaactttcc aaagttcctg
    36601 aaaagattgt gacctttgac ctcggcgctg cggatactat tcgcgcttta ggatttgaaa
    36661 aaaatatcgt cggaatgcct acaaaaactg ttccgactta tctaaaagac ctagtgggaa
    36721 ctgtcaaaaa tgttggttct atgaaagaac ctgatttaga agctatcgcc gcccttgagc
    36781 ctgatttgat tatcgcttca ccacgtacac aaaaattcgt agacaaattc aaagaaatcg
    36841 ccccaaccgt tctcttccaa gcaagcaagg acgactactg gacttctacc aaggctaata
    36901 tcgaatcctt agcaagtgcc ttcggcgaaa ctggtacaca gaaagccaag gaagaattgg
    36961 ccaagctaga caagagcatc caagaagtcg ctactaaaaa tgaaagctct gacaaaaaag
    37021 cccttgcgat cctccttaat gaaggaaaaa tggcagcctt tggtgccaaa tctcgtttct
    37081 ctttcttgta ccaaaccttg aaattcaaac caactgatac aaaatttgaa gactcacgcc
    37141 acggacaaga agtcagcttt gaaagtgtca aagaaatcaa ccctgccatc ctctttgtca
    37201 tcaaccgtac ccttgccatc ggtggggaca actctagcaa cgacggtgtc ctagaaaatg
    37261 cccttatcgc tgaaacacct gctgctaaaa atggtaagat tatccaacta acaccagacc
    37321 tctggtatct aagcggaggc ggacttgaat caacaaaact catgattgaa gacatacaaa
    37381 aagctttgaa ataagccact tcaaactcaa tttaatactc aatgaaaatc aaagagcaaa
    37441 ctaggaaact agccgcaggt tgctcaaaac actgttttga ggttgcagat gaaagctgac
    37501 gcggtttgaa gggattttcg aagagtataa aattttgaca ttctaaaacg catcctatca
    37561 agttcactca aacctgatag gatgcgtttt tatcattttg aaatctattt accccacctc
    37621 attccccttc ttgatttcgt ttaagggaaa agtggtctgg aacggggtcc ttacctgttt
    37681 tcgaccaggg atgacaacgt aaaatccgag ccaagcccat caataccccc ttaaaaccat
    37741 gtttttcaat agcctgaatc atgtagttgg aacaagtcag ctcaaagcga caagagggtg
    37801 gaaagactgg tgagataaaa cgttggtaaa agcgcacagg cgctattaaa attcgtttca
    37861 ttatttctta gttacagcca tggtgtgtag ttggctgatt tcttttttat taagacgacg
    37921 ggattctcct ggacggagtc ctgtcaagtc taggtgtccg aaacgagtcc gagacaactt
    37981 atctacttgg agaccaacag cttcaaacat ctttttaacc tgatggttac gcccttcatg
    38041 gatggtcaac tgcaccacag agcgattttt gactgggtcc actttgagaa tttcataaac
    38101 agctggcttg gttttcttac catcaatctc aagaccacgg gtcaaggggc ggagattgtc
    38161 cttattggcc acacccttaa cacgcgcgac ataaaccttg tcaatctcat tacgagggtg
    38221 aatcatctcg tctgtaaagt ccccatcatt ggtcaaaatc aagacacctg atgtatccca
    38281 gtccaaacga cccacagggt aaatacgctc tttgacattg ggcaagaggt cgacaaccgt
    38341 cttgcgaccc ttatcatctg tcacactgga aatcacaccg cgtggtttgt taagcagata
    38401 gtagaccttt tcttcgttgt agataggttg accttcaact tcgaccttgt cgcctgactt
    38461 gatagtggtt gctagttcac gcaccacttg gccgttaacc gtcaccaagc cttgcttaat
    38521 cagctcttct gcttttctcc tactggccac acctgcgtgg gcaatatact tattgattct
    38581 catcttcttc tatcctttca ccaaataatt ggctttcttg ggcttgaatc tcaagctcat
    38641 caatcactgg taattcttct aaatggttta tccccatgta atctaggaaa taatccgtag
    38701 tcacatagag gttggggcgc cccaatactt cctttttccc gtcttccttt atcaggtcaa
    38761 aagcctgcaa ctttgccaag gctccactcg agttaactcc acggatggca tcaatttcta
    38821 tccgcgtaat cggctgtttg taggcaataa tggacaaggt ctcaagggca gcccgagaca
    38881 agctctggtt gataggcgcc ttagagtatt ccttcaaaat ctctgcaaat tgagacttgg
    38941 tcaccaatct ataagcacca cttgtctcaa tcaaagccaa actggaatct gggtcctttt
    39001 catacttctg ggctaatttt cctaaactct gctggatgcc tgtcggtggc agagagagga
    39061 gttcagctaa ctggcggacc cgaatcccat cttcacccgc tacaaacaag agcgcttcta
    39121 tttttgctaa agtactcatc tttcctctct atcaagtcta gctttgaggc acttgacttt
    39181 cttccttctt ttccatgaga tagatatctc caaaactctc ctcttgcacg aggatcagct
    39241 cctgggtttt gattaactct agggttgcca aaaagagggt gatgacctct tggacattct
    39301 gggcttcctt gaacaaatcc tgcaagcgca attgatctcg tccaatcaag gactctttca
    39361 cgataatcat catgtcctca atcttatact catcccgcaa gatagtcgtg tgattttgtg
    39421 caaactcctc ttttttcttg gctaggatat ttgaaaaagc caaaaagagg tcaatggtcg
    39481 tcttgtcatg cacaagctcc gcatcttcgt aaatcaactc tgtcggcgct ttggaataat
    39541 actgggcccg ttcttggtgc ttggcttcca agtgctcacc caagagcttg aacttgcgat
    39601 attcttcgat ttgagagagg aggtcctgct ccaggtcatc ccccaagtct gtcacttctg
    39661 ctaccttcgg aaggagttta cgactcttaa tcagcatgag ctgactagcc atgaccatgt
    39721 actcacccgt cacttccaga cgcatggcct gcagggttga aacataggct agatactgtt
    39781 cgatgacttc cgtaatgggc acatcgtaga tatccatctg gtacttagaa accagatgca
    39841 agagcaagtc cagggggcct tcaaaatctt ttaatttaat atccattatc tatatttttc
    39901 taaggtcagg actgttttta atcctaattt ttttgcaatt tcgtacaaat cgaccttgtt
    39961 ttctatttgt cttagaataa actgttcacg taagacttga gctgataagg atggaaaacc
    40021 tttctccttg acaaaagatt ctaactgacg aaaggcccac tgacgagaat agggtttctc
    40081 tcctctttca aaaagatagg tctgccccat caagggttcc aattctgaaa gcaaggccgt
    40141 gggaatggtg acaatcctct gttgggaagc cttgctgatt cgcaacacct gaaaatccag
    40201 attgatgtcc gcaaccttga tggctaaaat ctcactgggc aagagcccca tttctaggat
    40261 taagagcgct agcaagcggc cctctggatg gtcgctttcc tgccaaaaag agtctaggta
    40321 tagaatctct ggcttttccg tcttcttttc agcttgtttg gctaattcca agcggtaaaa
    40381 gctgtccacc tctccttttt gatagagaaa gtatagaaat tggttacagg ccgaaatctt
    40441 tcgcttctgg gcgctgattt ttagattggc tagctgggct tggtaaatct tgagactggt
    40501 ctcagaaatc cgctcaccta ccatgtctaa aaattgctcc aaatcatact tataggactg
    40561 cttggaattg acagacaagc cctgcttttc ctctaaaaag gctgaaatcc tgtctctcat
    40621 tggcatcgaa tctcatattc cttactaaag tcatgcaaga gggcattaac ggccttgagg
    40681 atggacttac gcgtaataat cccttggaaa ataccctctg catccacaac cggtaagaag
    40741 gactcatcta ctagcttgtg caagacctcc gtaatggtga aatcaggcga aacaaccgct
    40801 acgtccgttt ttgtcatatg aacgatatcc gtatccgcca tgatttcttg gctcaagtca
    40861 tgctccatct gataagccat aatatctctg agtccaatcg tcccaacaaa ctgtttttca
    40921 tctgtcacaa cgggaacacg ggtataggtc atctgactga gcaagagggt cgcatgatcc
    40981 gcattgtggg tatcaatcaa cacagctaga tttttagcag gggtcaaaaa agtttcctcc
    41041 tgccccaaca agaaagtctc aaactccttg gcaatcatcg gctaaactcc ttggacaaac
    41101 ctggatacac ctcgtgatct cgtgtcaaaa agtccacttt gaagtaacta tcatcaatct
    41161 ccacacgagc atagagacat tctctgatgg tacctcgtgg ttgactgata gaacctggat
    41221 ttagaaagag gatcttgcct tccaaccaag cacttggcac atgcaagtga ccatagaggc
    41281 agatagcggc ctcttcctcc tgagcccagt agtccaactt ttgaaagttg aaattgatgt
    41341 caaacaagtg accatgagtt tggataatct tggtcgaacc aagctcagtc accagacgtt
    41401 ctgggtagcc ggcgtagaag tccatgtttc ctttaacaac gcggatgccc tcccaaagtg
    41461 gagaatccgg acgtagttca gaatcgccgt tatgaaaaac ggcatcgact ttgcccacat
    41521 agcgatcacg gacttcttcc acaatcaagc tatcgccatg ggaatcgctc attacaatga
    41581 tggtttgctt tgccatgatg gaaatacctc caaaagtttc ttaacggcta aggcacggtg
    41641 agattgacta tttttttctt ccagggttaa ttcagctgat gacttacctg tctctcctac
    41701 aaggaagagg ggatcatagc caaagccatt ttcaccctta ggttcaaagt taatataacc
    41761 tgaccagtct gcttcaacaa ctaaactttc cttatttggg ctggctacga ctagggttgt
    41821 gtggaactga gccgagcggt ccttgagttc aaagaccatg gccaattcgt gcaagagttt
    41881 ggcattattt tcacggtcag ttgctcccac acctgcgaaa cgagctgacc agacgcctgg
    41941 taagccacca aggacatcga ctttgagacc agaatcatct gccaaaacca tcttgcccgt
    42001 taattgagaa atggtttctg ccttaaggcg ggcattttct tcaaaggtca tacctgtttc
    42061 tgctacttca ggcaggtcag ggtagtcatt aagattttcc acatcgtagc ctaacttatc
    42121 aaagatagct cggaattcct tggttttgcc ttcgttacga gtcgcaatca acaaggtttc
    42181 tctgaccttg cttgtctcaa agaaatcatg aacattgacc ccttctttag gcaattctac
    42241 atacaagagt tgcccatttt caaccaagag cagggcccca tgacgttgaa taacttccaa
    42301 gtttcgtccc atttcttgat taagcatgtc taccacaaag gagaacaaac ggtaggtaga
    42361 accatagcgt aaaacagtaa ctgaaagcgg gaaaccatac tcttcatctc caaatatttt
    42421 ggagaattca aacagaggaa aatctgtctt atagtcgctc aaactgttaa cgccaccaaa
    42481 aatactataa gacccaacat accaatcctg gtcatcctta tattcataaa ttttatttgt
    42541 cataattcta catgctccac ataaatctct ttttccagcc attcttcacc aatttgtgca
    42601 aaactttggc tactggctgt tgtgtaaaaa cggtgatgga gtggtccagc atcgcgacca
    42661 cgattgattt caaaataatt gagtaagact gagatatccc gtacgcactc tgccccacta
    42721 tcgatgagct gaacctttgg ccccatgaca ttttggataa tagggcgaag gagtggataa
    42781 tgagtacagc ccaaaatcag gctatccacc tttccaacca agggacgcag ggtttcatag
    42841 accaccttct tggtaacact ggttgacagg gcacctgact caaccaaggg agcaaacttg
    42901 ggacaggcca agctctccac ctgtaagtcg ggatccagat catggatttt ctgacggtat
    42961 atgtctgatt gtaccgtcat gggcgttcca atcactccga ttttcccacc ttgactggac
    43021 ttgatggctg ccgaagctcc tggcaaaatt acacccaaga caggaatatc tagttgagcc
    43081 ttgatttctt cccagacgac cgcagtcgca gtgttacaag caatgacaat cattttgaca
    43141 tccttggtca agagaaagtt gaccagctgc caagtatatt cacgaatttg ctcagctgga
    43201 cgggggccat agggcgcccg cgccgaatct ccaatataga cgatttcttc atggggaagc
    43261 tggcgcatga gctcgcgcac aacggtcaag cccccgacac ccgaatccaa aaaaccaatt
    43321 ggtcgattat ccatacagtc ttctttctag tcttttttct gattgatcgt tcattatgat
    43381 tccttgtact gaacgaactg accgacagct tgatagaatg tcaactacct ctctcttaat
    43441 cataatcaaa tatcaataga atgcaaggaa aaagtctcat ccctaaacca taaccaacat
    43501 agtgagaagt ctggaacttt catcccagac ttttccttat ttattttttc tttttattgt
    43561 tagcaagggc tgccttttgt tggcggatga tttggtggta aacttgttgt accttagctt
    43621 cgcttggttt ttgaccattt gcactcaaaa gagtacgaac tgcttcagca ttcaaacgtg
    43681 ggttgtcagc aaattctttt tcgatttgct tacgaaccaa gtacattcct ccaagagctc
    43741 ctcctagaaa agctagcaca atcaatacaa ttgctaaaag taaatccatc atttttctcc
    43801 tgtttctttt tgagtccctt tcattatacc acaaactagc caccctgacc agtttgttct
    43861 acactttcag ggatggaata gacagcaaaa agaaccctgc ttttctgaaa aagaggtctc
    43921 cttgctaagt ttaatttaca taaatagcca gtgtttgata gggttttagt agaattttct
    43981 cagacacttc tgcatcttca tagtttgaaa tcaaaatctg tccattttgg tagactgctg
    44041 gcaagtcgat ttccacttct ttagcataaa agttattgag cactagtaac ttttgatcct
    44101 caaactggcg ttcaaaagcg tagacttgtt tgctatcttc aaaggctggt ttgtaacttc
    44161 cttctgaaat gattggcatt tccttacgca gtcgaatcaa gtcttgatag aaggtaaaaa
    44221 tcggaccctg gatttcattt tctacattga tgtctttata ggatttacca gctttcaacc
    44281 aaggagtgcc tgttgaaaat cctgcatttt ccgaagcatc ccactgcatg ggaatgcgtg
    44341 aattatcacg cgacttagct tgaataatct ggaaggcttc ttgctgactc tttccttctt
    44401 ctaggagcat ctgataggca ttaagcgatt cgacatccac gtaatcagcc atagaatcat
    44461 agtctgggtc aatcatcccg atttcctcac ccatgtagat ataaggtgtc ccacgtgaca
    44521 ggtgaatgct ggctgctagc atggtggctc cttccttgcg gaagttttga atatcgacaa
    44581 aacggttcaa ggcacgtggt tgatcgtgat tgttccaaaa gagggcactc caaccgtctt
    44641 tatcactcat ttccttaccc caactatggt aaagactctt caactcttca aaatcaaagg
    44701 gagccaaggt ccacttttgt ccatccttat agtccacctt gaggtgatga aaattaaagg
    44761 tcatggataa ttcctgacga tcaggcgacg aatagaggac acagttttcc atggtggtag
    44821 aagacatttc cccaactgtc ataaagctat cgtcagatcc aaaagtggct tggttcatca
    44881 tacgcaaata gttatgaacg atgggtttgt ctgtataagc tggcttccct tcattttcag
    44941 gacagtccac tgaaacctcg tccttaccaa tcaaattgat cacatcaaat cgaaaacctt
    45001 tgacaccctt gtcgcgccag aaattaacaa ccttgaaaag ctccttacgg acattgggat
    45061 tgcgccagtt aaggtcagcc tgggtctcat caaataggtg aagatagtat ttcccagtat
    45121 ccccgaaagg cgcccatgca gaaccaccaa acttagactg ccaatctgtt ggttggtctt
    45181 ggatgaagaa aaagtcttga taatacttat caccagctag ggctttctga aaccattcat
    45241 gctctgtcga acaatgatta agtaccatgt ccagcataaa gtcaatcttg tgctctttac
    45301 cgatacacac catttcctca aaatcagcca tatcaccaaa aagaggatcc actgccatat
    45361 aatctgaaat atcgtaacca ttatcccgtt gaggacttgg atagaatgga ttgagccaga
    45421 ccatatccac acctagtttg gctagatagg gaatttttcc gataatccca cggaaatccc
    45481 caataccatt gccagtggtg tctttgtaag attttggata gatttgatag actacttttc
    45541 ctttatcaag tgtcatctgt ttctcctttt ctgataaaag ggaggaagca gtcttccgtc
    45601 cctatttgtg ctatttcaat tatactcaat gaaaatcaaa gagcaaacta ggaagctagc
    45661 cacaggttgc tcaaaacact gttttgaggt tgcagataga gctgacgtgg tttgaagaga
    45721 ttttcgaaga gtattagatt cgtgtagcga ccatgagaga tgctccagct tgaatcgttg
    45781 tcggataagt tccgggaata gtcgctgtat aagcatcttg gttggtgatg ataacaggag
    45841 tttctgtcac cagacctgca gccttaatga catccatatc aaaacgaatc agttgctgac
    45901 caactgtaac gtgatctcct tggactacaa gactttcaaa acctttgcca tcaagaccta
    45961 ctgtatccat accgatgtgg atgagcaatt caactccctc gtcagagaca atgccgatgg
    46021 catgcttggt agggaaaaga accgtcactg tcccattaac tggagaggtc aactcacctt
    46081 ggcttggttc aatgactaga ccttgcccca tgacacctga tgcaaaaata ggatccgtcg
    46141 cttgactcaa ttctttcact tggccagtta gtgggctgat aatttctacc gaagtaagtt
    46201 ctactggttc atggttcaca aattctgctt cttcttgagc aacgaattct gcctgcaagt
    46261 tcgtatcgcc ctctgttttt gtaaagagac cagccttgcg gaagaagaaa gtcaagagca
    46321 ttggaacaac aatcgcaact agcatagttc ctgcaaatgg cagcatgtat tgaggttgaa
    46381 tagagagaat acctggcaaa ccaccgatac caatagaagc cgcagttaca ttaaaagtaa
    46441 cggataacat gcctgcaagg gctgaaccag tcatcccagc aacaaatgga taaatatatt
    46501 ttacgttaac cccaaaaaga gctggttctg taacaccgag ataggctgaa atggttgcag
    46561 gaagtgaaac ctgagcctca cgctcatcat ggcgatgcat gaaataatag gcaaacacgg
    46621 ctgagccttg agcaatatta gaaagagcaa tcattggcca tagggcagtg ccaccagcat
    46681 ccgcaatcaa ttgtgtatca atggcattgg tcatatggtg cagacctgtg atgacaaatg
    46741 gagcgtagag ggcaccaaaa attgcaccga agagccattt aactggacca gttaaacctg
    46801 ccaagacaac tgatgaaagt ccttgtccaa ttgtccaacc gattggtccc aaaacagtat
    46861 gagccaaaat caaggctgga atcaatgaca agaaaggtac aaaaatcata gaaatgactt
    46921 ctgggatatg cttgcgccag aagatttcaa gataagatag actcaaacct gcaagcaagg
    46981 ctgggataac ttgggcttgg taaccgatac gattaacagt aaaatagcca aaattccaaa
    47041 cccagtttgc cgcgatatca gctgctggcg ttgaagcaac cgcataggca ttgagcaact
    47101 gaggcgatac caaacagatt ccgagaacaa ttcccaaaat ttggctggtt cccatcttac
    47161 gagaaacaga ccaagtaatc cctactggta agaactggaa gatagcttca ccaggcaacc
    47221 agaggaaatg attaacacct gcccaaaact gagaggattc tgtgatggtc ttgccatcca
    47281 acatcgacca atggacacct tccaagacat tacggaaacc gaggatcaat cctccgacta
    47341 tcaaggctgg aataatcgga gtaaaaatct ccgccagagt ggtcatgaca cgttggacca
    47401 cgttttgatt actcttagct gcagacttgg ctgcttcttt ggaaacaccc tcaatacctg
    47461 aaacagctgt aaaatcatta taaaagatgg gcacgtcatt tccaatgatt acctgaaatt
    47521 gacctgcatt tgtaaaggtt cctttaacag ctggaattga ctcgatagct ttaacattag
    47581 ccttcttatc atttcctaaa acaaagcgca tccgtgttgc acagtgagtt acggcagtca
    47641 cattttcttt gcctccgatt gcctgaagca gatctttggc ttcttgttca aattttccca
    47701 tttgattctc cttatacttg tcaaagcaag tttgatttga taagtatatt gtaaacgata
    47761 ccaaacttgt ctgcaacttg tttggtataa aaagggtgtt tttttgtaaa ttttctagca
    47821 cttgtatggt aaaatagata caggtgttca ttaaactaga ctaaaaacct atttaagcag
    47881 gcaaaatgaa gaaataccaa caattattta agcaaatcca agaaaccatt caaaacgaga
    47941 cttacgctgt cggagatttc cttcctagcg agcacgacct tatggagcaa tatcaagtga
    48001 gtcgtgatac cgtccgaaag gccctgtctc tcctccaaga ggaaggattg atcaaaaaga
    48061 taagagggca aggttctcaa gtcgtcaaag aagaaaccgt caatttccct gtatccaacc
    48121 taaccagcta ccaagaacta gttaaagaac ttggactgcg ctctaaaacc aacgtggtca
    48181 gtctggacaa gattattatt gataaaaaat cctcactgat aaccggtttc ccagagtttc
    48241 ggatggtttg gaaggtggtc cgccagcgtg tggtggatga tctggtatcc gttctggata
    48301 cggactatct ggatatggaa ctcatcccaa atctcactcg ccaaattgct gagcagtcta
    48361 tctattctta tatagaaaat ggcctcaaac tccttattga ttatgctcag aaggaaatca
    48421 ccattgacca ctcaagcgac cgagacaaga ttctcatgga cattggcaaa gacccttatg
    48481 tcgtttcgat taaatcaaaa gtctatctcc aagacgggcg ccaatttcag tttaccgaaa
    48541 gtcgccataa gttagaaaaa tttagatttg tagattttgc aaaacgcaag aaataaaaga
    48601 ctgagacacc agatctcagc ctttttcttt atcccaaaac taattcatca ctgaccagac
    48661 tttggccact atttttctgg aagagatgca taaggtcttc aactgtcaga tgctttttct
    48721 cttctccctt gacatccacc actatcttgc cttgatagag cataatgaga cgattgccgt
    48781 actcaatcgc atgattcata tcatgggtaa tcatcaaagt cgtccactga tggtactcca
    48841 caatcttttg cgtcaagtcc atcaccattt gactggtttt cgggtcaagt gccgcagtat
    48901 gttcatccaa aagcaaaagt ttgagtttca ccagagctgc catgactagg gtcaaagcct
    48961 gtctttgtcc tcctgagaga tattgagtat ctacttttaa gcggttttca agaccaatat
    49021 tcaactcctt caaggcctct tggaactgga ttctatcctt ctccttcacg ccccaaccaa
    49081 gccctctctt ttgcccacgt ctcaaggcaa tagccatatt ctcctcaatc gtcaaacgag
    49141 aagctgttcc catcttagga tcttgaaaaa cacgggcaat atccttggct ctctttctga
    49201 cactcagatg tttaatggat ttccctgcca gtagaaggtc cccttcgtcc accgatagat
    49261 taccagccaa gatattcatc aaagtggatt ttcctgctcc atttccacca atcacagaga
    49321 taaaatctcc ctcttcaacc tctaaatcta atcctttgag gacatggttc tcattgaccg
    49381 tccctgcttc aaatgtcttg tgaatatttt caagtgttaa caaacttgcc ataactttct
    49441 cctcctattc atttctcaat ttcagaccac gaatctttaa tctcttttgc aatgctggtg
    49501 caaataaaac caaagcgagc aagattgcat taaagagacg taccaagttt tgatctagat
    49561 ttggaatttc atagatattt aaaataatca aacggtaaac aatagcaccg attccgatgg
    49621 ataataagcg gcctccaatg gtcaagtcgt gtatcaagac ttccgagctc aaaccaacaa
    49681 caatggttcc tgtcccagaa gtcacatctg aaaatccatc attttgggca aacaaggaac
    49741 cacatagggc aatcaaaccg gttgaaatca tgtaaccaac aatcttcatg gtgtttacat
    49801 tgactccatt ggcctcactc atcgggatat tgtccccagt cgaacgcaag accaaaccaa
    49861 tctctgtttt catcaaaagg gtcaaaacca aacaagtaag agacagacta aactaagtga
    49921 gaaaacagct ccttcatttg tcagacccaa gctcgccaac tgtttaaaga cggttgcaga
    49981 atctcccaag gaaagattgg gtacactgcc catgatttta atattgattg aatagagccc
    50041 tgtcaaggtc acaatccctg tcaagagagc tgggattttc atcttggtgt ggagcattcc
    50101 tgatataaga cctgctacca tacctgccag caaagcaagt aaagtcgcaa gccaaggatt
    50161 tgcccctgcc tgtatctgtg atacaacgat tgctgccccc ataggaaagg ctccctcagc
    50221 agtcatatcc gcaatatcca aaatacggaa agtcaagtag accccaattg ccataatcga
    50281 ccacaacaaa ccttctgata aactagataa cacaaaattc atcttaatcc tccttattcc
    50341 ttgccttcta acttactaat atcaattcac aatgcatctg ccatttcttg attagtatgc
    50401 aattccagtt tttcaggcaa ctcaactgct atattttctg gttcctcacc ttttaaaaca
    50461 cgaatcagca tgcgagctgt ctgtcttccc aattcttcat aattggttcc gtagttatac
    50521 aagccaccaa cagcaatcat ttctgttgaa ccaccgaata ctggaacctt gtgtttaata
    50581 gaaacctgct taactgtttc catggttgac gaaatgatat tatcagttgg gacaaaaacc
    50641 atatccacct ctgccatcaa actctctgct gccgccttga cgttattact gtccaagatt
    50701 gttttttcaa caacggtaaa gcctttttct ttcagaaatc gcttagcttc atccttttaa
    50761 acaaccgaat tgggctcgct ctgagtatag aggattccaa tcgttttagc ctttagcaac
    50821 actttcttta tcaaattgat ttgggttgaa atggcatctg atgactgatc gcttgtccca
    50881 gttacattgc ccccaggatg ttctcttgac tcaaccaact tggcactgac tgggtctgtt
    50941 acagctgaaa agataactgg tgtcgtttgc gtcgtattgg ccaagctctg agcagaaggc
    51001 cttgcgatgg ctagaacgac atcgctggat tctgctagtt gctgggaaat cgtttttaga
    51061 tttctttgtt ctccctgtgc attttgcaaa tcaatctcaa tattttcccc ctcaacatag
    51121 ccttgtttgg ccagctcatc cacaaatcct tctctagtag cgtctaagga ctggtgggta
    51181 ataaactgcg aaataccgat acgaaagaca tctcttttct tatctgcctt caactgatgc
    51241 aaactgatca gagaagtcaa gaggatcccc actaccaaga gggggctagt gattttcgaa
    51301 caactttcat aatgaaactc cttctcagaa aagataaaac aaaaaaacgc ctagatacta
    51361 tctaaacggg tacttgaaat aacctaacaa gttacaactt agctggtcca tttagatatt
    51421 catctatatg gaccacaatc aaaaatctta gccacataga tacaaacaaa ttgcttgaac
    51481 tgtttgcatc catggtgaca tgtctacaaa cactatctaa agtagctaaa gtaaaagttt
    51541 tgattcatag ttacggcttg tctcttattc atttcttttt ctgctttctt ttttgatcct
    51601 tcctatccta ccaccttttt catcacctgt caataatatt tcaaaatttt ttaaaatttt
    51661 tcgaaaattc tttcag
//
LOCUS       DAVBCA010000006        50151 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.006, whole genome shotgun sequence.
ACCESSION   DAVBCA010000006 DAVBCA010000000
VERSION     DAVBCA010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 50151)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50151)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50151
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.006"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..746
                     /locus_tag="VQU19_000316"
     CDS             <1..746
                     /locus_tag="VQU19_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HET2479631.1"
                     /translation="YELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTD
                     KKFVFIIDEINRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVY
                     IIGTMNDIDRSVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAA
                     IENVQELNSHYHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLK
                     KAFELTNNEQKDQAVADDNESDENDDADY"
     gene            733..2085
                     /locus_tag="VQU19_000317"
     CDS             733..2085
                     /locus_tag="VQU19_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HET2479632.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKKQKILETINQEIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLHINLTSLDVALSREERLYQLLMYLFPKYLQAAIRKGLYKEYHRFSHNDSHVKGV
                     IDVRNHLKKNLPFTGNIAYTTREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKIIRGNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLVFPSKDKVIDNEMGNL
                     AGYGALLKKWSIQIPQKSSSYSAFCKMMENSDYSAFCKMMENSEENFKAIIDEEVGRK
                     "
     gene            2260..3246
                     /locus_tag="VQU19_000318"
     CDS             2260..3246
                     /locus_tag="VQU19_000318"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HET2479633.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKQMHDQGLIASISVGVKDYEY
                     DFVSQLKTDAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            3310..3381
                     /locus_tag="VQU19_000319"
     tRNA            3310..3381
                     /locus_tag="VQU19_000319"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3343..3345,aa:Arg,seq:ccg)
     gene            3564..4262
                     /locus_tag="VQU19_000320"
     CDS             3564..4262
                     /locus_tag="VQU19_000320"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HET2479634.1"
                     /translation="MKELQTVLKNHFAIEFADKNLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            4253..7792
                     /gene="smc"
                     /locus_tag="VQU19_000321"
     CDS             4253..7792
                     /gene="smc"
                     /locus_tag="VQU19_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HET2479635.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKSEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAALEDKRNS
                     LSKEKSDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLAIAKEKASQQKEELETAKEQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDNLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDMHYQTALEIALGASSQHIIVEDEESATKAIDFLKR
                     NRAGRATFLPLTTIKARTISSQNQDAITVSPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDAVEHARAAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAADEASLRSEEAALKTLQDQMATLTERLEVIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEEIDRLSEGDWQADKEKCQDRLAAIASDKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVADIERLGKELDNLDFEQEEIQRLLQEKVDN
                     LEKVDTELLSQQAEEAKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRYLQSQLTDQYQISYTEALEKAHELENLNLAEQEVQDLEK
                     AIRSLGPVNIEAIDQYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKDRFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            7789..8583
                     /locus_tag="VQU19_000322"
     CDS             7789..8583
                     /locus_tag="VQU19_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET2479636.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFAGVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGETWVNDNVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKDQSVIAYMEGL"
     gene            8583..9401
                     /locus_tag="VQU19_000323"
     CDS             8583..9401
                     /locus_tag="VQU19_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET2479637.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKATLKAASDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGHEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            9405..10625
                     /gene="ftsY"
                     /locus_tag="VQU19_000324"
     CDS             9405..10625
                     /gene="ftsY"
                     /locus_tag="VQU19_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HET2479638.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVS
                     QEEAVLEESQDSEPAVGVSQEEIEELPEEEKLEHEGTIEENNSEVLEAERPQTEETVQ
                     EKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEELEELLIMSDVGVQVASNLTEELR
                     YEAKLENAKKPDALRRVIIEKLVELYEKDGSYDESIHFQDNLTVMLFVGVNGVGKTTS
                     IGKLAHRYKRAGKKVMLVAADTFRAGAVAQLAEWGRRVDVPVVTGPEKADPASVVFDG
                     MERAVAEGIDILMIDTAGRLQNKDNLMTELEKIGRIIKRVVPEAPHETFLALDASTGQ
                     NALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAIREELNIPVKLIGFGEKIDDIGEF
                     NSENFMKGLLEGLI"
     gene            complement(10671..12158)
                     /locus_tag="VQU19_000325"
     CDS             complement(10671..12158)
                     /locus_tag="VQU19_000325"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HET2479639.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYQSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPAIFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRSVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVGASWKLIDRIEELWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDIAYRQDGRFE"
     gene            complement(12307..13047)
                     /locus_tag="VQU19_000326"
     CDS             complement(12307..13047)
                     /locus_tag="VQU19_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET2479640.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEELGMELLEKVGLADKANANPDNLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(13047..15212)
                     /locus_tag="VQU19_000327"
     CDS             complement(13047..15212)
                     /locus_tag="VQU19_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HET2479641.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALAEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            15385..16338
                     /locus_tag="VQU19_000328"
     CDS             15385..16338
                     /locus_tag="VQU19_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2479642.1"
                     /translation="MKNKRIFKDFQASKMNLNLYTSPLLAFVFVFIGEFVAYTLYGIS
                     LLALIGLARNFGEAGQNLASYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENCLSNLLKGFSLGLALFLLTLLSLVVLGQYRLESIHLNPYYLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            16415..18403
                     /gene="uvrB"
                     /locus_tag="VQU19_000329"
     CDS             16415..18403
                     /gene="uvrB"
                     /locus_tag="VQU19_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HET2479643.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            18413..18976
                     /locus_tag="VQU19_000330"
     CDS             18413..18976
                     /locus_tag="VQU19_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2479644.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKTNDGYYQINGNS"
     gene            18942..19430
                     /locus_tag="VQU19_000331"
     CDS             18942..19430
                     /locus_tag="VQU19_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2479645.1"
                     /translation="MTVIIKSMETPEEIEGKPLVHWQTWREAYDGLLPAEFQETMTLE
                     RCRFFSQKYPENTLIAMDGMKVVGFISYGNFRDETIQAGEIIALYVLKDYYGKGIAQK
                     LIKAALIALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDEQEKILELGKPIKEKRMVFY
                     SK"
     gene            19503..19970
                     /locus_tag="VQU19_000332"
     CDS             19503..19970
                     /locus_tag="VQU19_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HET2479646.1"
                     /translation="MSRAQLTILTNICLIEDLEAQRVVMQYRAPETNRWSGYAFPGGH
                     VENGESFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVVCYKATEFSGTLRS
                     SDEGEVSWVQKDQIPNLDLAYDMLPLMEMMEASDKSEFFYPRRTEDDWEKKIF"
     gene            complement(19967..20482)
                     /locus_tag="VQU19_000333"
     CDS             complement(19967..20482)
                     /locus_tag="VQU19_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HET2479647.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFKPLSELTDGVHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(20494..21021)
                     /locus_tag="VQU19_000334"
     CDS             complement(20494..21021)
                     /locus_tag="VQU19_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET2479648.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGSLYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            complement(21299..21862)
                     /locus_tag="VQU19_000335"
     CDS             complement(21299..21862)
                     /locus_tag="VQU19_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET2479649.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            complement(21846..22397)
                     /gene="coaC"
                     /locus_tag="VQU19_000336"
     CDS             complement(21846..22397)
                     /gene="coaC"
                     /locus_tag="VQU19_000336"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HET2479650.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            complement(22409..23098)
                     /gene="coaB"
                     /locus_tag="VQU19_000337"
     CDS             complement(22409..23098)
                     /gene="coaB"
                     /locus_tag="VQU19_000337"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HET2479651.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISADQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            23328..24998
                     /locus_tag="VQU19_000338"
     CDS             23328..24998
                     /locus_tag="VQU19_000338"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HET2479652.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELEIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAVL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNALSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            25326..26501
                     /gene="mutY"
                     /locus_tag="VQU19_000339"
     CDS             25326..26501
                     /gene="mutY"
                     /locus_tag="VQU19_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HET2479653.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     LIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            26556..27260
                     /locus_tag="VQU19_000340"
     CDS             26556..27260
                     /locus_tag="VQU19_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2479654.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            27253..28602
                     /gene="vicK"
                     /locus_tag="VQU19_000341"
     CDS             27253..28602
                     /gene="vicK"
                     /locus_tag="VQU19_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HET2479655.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            28604..29413
                     /locus_tag="VQU19_000342"
     CDS             28604..29413
                     /locus_tag="VQU19_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HET2479656.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            29504..29746
                     /locus_tag="VQU19_000343"
     CDS             29504..29746
                     /locus_tag="VQU19_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HET2479657.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            29748..30002
                     /locus_tag="VQU19_000344"
     CDS             29748..30002
                     /locus_tag="VQU19_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HET2479658.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEDPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            30049..30822
                     /locus_tag="VQU19_000345"
     CDS             30049..30822
                     /locus_tag="VQU19_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ion transporter"
                     /protein_id="HET2479659.1"
                     /translation="MKKKWFFADYYDTTIILLALISVILVLLGFAEMIDLDNPPYSII
                     DLVIWGVFVIDYSWRFFTTKRKWRFILENIFDLLAILPLNAIFTVFRLGRIFRLAKLT
                     KLLKLTRLLRIIGLTGKLERKISRFLRTNGLIYILYVNIFIVLVGSSILSVVEEKSFS
                     DSLWWALVTVTTVGYGDIVPASIFGKWLAVLLMLVGIGTIGMLTSALTNFFVKDNPDE
                     QIKLDKLKDELSSQRILLEKQSKKIEELHKMIQDLIEKT"
     gene            complement(31082..32068)
                     /locus_tag="VQU19_000346"
     CDS             complement(31082..32068)
                     /locus_tag="VQU19_000346"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HET2479660.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGLYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            32262..34730
                     /gene="gyrA"
                     /locus_tag="VQU19_000347"
     CDS             32262..34730
                     /gene="gyrA"
                     /locus_tag="VQU19_000347"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003244540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HET2479661.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIALRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMIGQVLSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEE"
     gene            34730..35473
                     /gene="srtA"
                     /locus_tag="VQU19_000348"
     CDS             34730..35473
                     /gene="srtA"
                     /locus_tag="VQU19_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HET2479662.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQPYKQFY"
     gene            35717..36514
                     /locus_tag="VQU19_000349"
     CDS             35717..36514
                     /locus_tag="VQU19_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HET2479663.1"
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            36662..36784
                     /locus_tag="VQU19_000350"
     CDS             36662..36784
                     /locus_tag="VQU19_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent transferase"
                     /protein_id="HET2479664.1"
                     /translation="MTCDFKFETLQLHAGQVVAPATKSRAVPIYQTTSFIFDDT"
     gene            36806..37846
                     /locus_tag="VQU19_000351"
     CDS             36806..37846
                     /locus_tag="VQU19_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001231001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HET2479665.1"
                     /translation="MRKPGNIYTRITNPTTAALEGGVEALATASGMTAVTYTILALAH
                     AGDHVVAASTIYGGTFNLLKEPLPRYGITTTFVDVDNLEEVEAAIKDNTKLVLIETLG
                     NSLINIPDLEKLAEIAHKHQIPLVSDNTFAIPYLINVFSHGVDIAIHSATKFIGGHGT
                     TIGGIIVDSGRFDWTASGKFPQFVDEGPSCHNLSYTCDVGAAAFIIAVRVQLLRDTGA
                     ALSPFNAFLLLQRLETSSLRVERHVQNAETIVDFLVNHPKVEKVNYPKLADSPYHALA
                     EKYLPKDVGSIFTFHVKGGEEEARKVIDNLEIFSDLANAADAKSLVVHPATTTHGQLS
                     EKDLEAAGVTPN"
     gene            38017..39291
                     /locus_tag="VQU19_000352"
     CDS             38017..39291
                     /locus_tag="VQU19_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HET2479666.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMKQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHEALLAKDKEV
                     QLLENQLATLRLEHENQLQKTLSDLEKERDQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKDFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            39301..40179
                     /gene="truB"
                     /locus_tag="VQU19_000353"
     CDS             39301..40179
                     /gene="truB"
                     /locus_tag="VQU19_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HET2479667.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEIILGYSTTTEDASGEVVAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALTLEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            40447..40722
                     /locus_tag="VQU19_000354"
     CDS             40447..40722
                     /locus_tag="VQU19_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HET2479668.1"
                     /translation="MEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQSVMANLSQGL
                     SLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            40830..41468
                     /gene="udk"
                     /locus_tag="VQU19_000355"
     CDS             40830..41468
                     /gene="udk"
                     /locus_tag="VQU19_000355"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HET2479669.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            41596..42936
                     /locus_tag="VQU19_000356"
     CDS             41596..42936
                     /locus_tag="VQU19_000356"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HET2479670.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEK
                     RMATAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            42914..43126
                     /locus_tag="VQU19_000357"
     CDS             42914..43126
                     /locus_tag="VQU19_000357"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HET2479671.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            43123..43998
                     /locus_tag="VQU19_000358"
     CDS             43123..43998
                     /locus_tag="VQU19_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HET2479672.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLESLQVTIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFE
                     TESIVSVVESLRING"
     gene            43991..44806
                     /locus_tag="VQU19_000359"
     CDS             43991..44806
                     /locus_tag="VQU19_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HET2479673.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHSVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKIHQNVLESVTAMAVEA
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            44799..45230
                     /locus_tag="VQU19_000360"
     CDS             44799..45230
                     /locus_tag="VQU19_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET2479674.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            45237..46904
                     /gene="recN"
                     /locus_tag="VQU19_000361"
     CDS             45237..46904
                     /gene="recN"
                     /locus_tag="VQU19_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HET2479675.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRTIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLDLNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNKMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            46906..47634
                     /locus_tag="VQU19_000362"
     CDS             46906..47634
                     /locus_tag="VQU19_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HET2479676.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQPQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYSRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEAADLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            47713..49536
                     /gene="lepA"
                     /locus_tag="VQU19_000363"
     CDS             47713..49536
                     /gene="lepA"
                     /locus_tag="VQU19_000363"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HET2479677.1"
                     /translation="MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMELERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(49738..49818)
                     /locus_tag="VQU19_000364"
                     /pseudo
     CDS             complement(49738..49818)
                     /locus_tag="VQU19_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            49993..50151
                     /locus_tag="VQU19_000365"
                     /pseudo
     CDS             49993..50151
                     /locus_tag="VQU19_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
BASE COUNT        15257 a         8961 c        11378 g        14555 t
ORIGIN      
        1 tttacgagtt gtataaagat aaaaattata ataagcaaga atactacaaa agtggtggaa
       61 aaactgtcct agaaacattg agaaagagat ttggtttgaa agactatgtt tccccaacag
      121 aaattgatac tgataagaaa ttcgttttca tcatcgatga aatcaatcgt ggggagattt
      181 ctaagatttt tggcgaactc tttttctcta tcgaccctgg ctatcgtggt gaaaaaggaa
      241 gtgtttctac ccaatatgca aatctacacg aaactgatga aaagttctat atccccgaaa
      301 atgtttacat catcggaact atgaatgata ttgatcgttc agtggatacc tttgattttg
      361 ctatgcgtcg tcgttttcgt tttgttgaag ttactgccga gggtcaagtt ggcatgttgg
      421 ataaagagct gaatatccat gcagaagaag caaaaattcg tctaagaaac ttgaacgctg
      481 ctatcgaaaa tgttcaggaa ttaaacagtc attatcatat tggaccaagt tattttctta
      541 agttgaagga tgtagatttt gactatgaat tactctggtc cgattatatt aagcctctcc
      601 tagaagacta cttgcgaggt tcttatgatg aggttgaaac tttggaaact ttgaaaaaag
      661 catttgaact gacaaataat gagcaaaaag atcaggcagt agctgatgac aatgaaagcg
      721 atgaaaacga tgatgcggat tactgataat caacacaaga ttattaaaga aaaatttgtt
      781 gaagaatatc ctaaactaag caatcttctt ttagacagaa ccttggaaag tctatcccaa
      841 gatgaacgta ttttcatttt tccaaatgat ttgactcata ctccagattt ggataaaaaa
      901 caaaagattt tggaaacgat caatcaggaa atcaagacag gaaatgtgat tggttttctt
      961 ggatatggtc aggaaagatt aacgatttcc tcacgatttt ctgatgagag taatgaccat
     1021 tttttgcatt atctcttaaa caaggttctt catatcaatc tcactagttt agatgttgct
     1081 ttgtctcgtg aagagaggct ttatcaactt ttgatgtatc tcttccccaa gtatctacaa
     1141 gctgctattc gaaaaggtct ttataaggaa tatcatcgat tttctcataa cgacagtcat
     1201 gttaagggag tgattgatgt aagaaaccat ctcaagaaaa atcttccttt cacgggaaat
     1261 attgcctaca caacgagaga gttcacctat gataatcccc tcatgcagtt ggtccgtcac
     1321 actattgaat acattaagaa tcagaaaagc attggtcaag gggtactaga taatctctca
     1381 actagtcgtg aaaacgtatc tgaaatcgtg cgtgtaacgc cctcttataa actagctgat
     1441 cgtgctaaga ttattcgggg aaatcaatct aaacctatac gtcatgcata ctttcacgag
     1501 tacagaaact tacaagaact ttgtctgatg atcctaaacc aagaaaagca cggtttaggg
     1561 tatcaagatc aaaaaatcta tggtattctc tttgatgttg cctggctttg ggaagagtat
     1621 gtttacacct tgttgccaaa aggttttgta catcccagaa ataaggataa gacggatgga
     1681 atttcagtat tttctgttgg gaaacgaaaa gtatatccag atttttatga cagagaacga
     1741 aagattgttc tagatgcaaa atataaaaaa ctggaattga ctgaaaaagg aatcaatcgt
     1801 gaggacttat tccagctgat ttcctattct tatattttaa aagctgagaa ggctggactt
     1861 gtttttccga gcaaggacaa ggttattgat aatgagatgg gaaacctagc aggttatgga
     1921 gctttgttga agaaatggtc tatccaaatt cctcagaagt cttcatctta tagtgcattt
     1981 tgtaaaatga tggaaaattc agattatagt gcattttgta aaatgatgga aaattcagaa
     2041 gaaaatttta aagcgattat tgatgaagaa gtggggagaa aataatttcc cctctttctt
     2101 ttatttttaa cacaagtaaa acccgaacaa tatatttcaa ttcataaaat aatttgacaa
     2161 aaactgtact ttggtttata ataaattaag gaaacgtcgg aaaagacgta gtgatgcgag
     2221 agcataggta ggtcattaca aaagaaacga gacatcgata tgttaaatga atttccaatt
     2281 tttgattacg aagatattca attgattcca aataaatgtg tcattaaaag ccgtgcagaa
     2341 gcggatacaa gtgtcacttt aggaaatcac acctttaaac tacctgttgt gccagcgaat
     2401 atgcagacga ttttggatga aaatgtagca gagcaactgg ctaaaggtgg ttacttctac
     2461 attatgcacc gttttgatga ggcaggacgc attcctttta ttaaacaaat gcacgatcaa
     2521 gggctcattg cttccatctc tgtcggtgtt aaggactatg agtatgattt tgttagccag
     2581 ctcaagactg atgctcctga gtatatcact attgatattg ctcatggtca tgcggatagc
     2641 gtgatttcta tgattcaaca tatcaagaaa gaattgccag atacctttgt cattgctgga
     2701 aatgtgggaa caccagaagc tgtgcgtgaa ttggaaaatg ctggtgcgga tgctactaag
     2761 gtcggaatcg gtcccggtaa ggtttgtatc accaaggtta agactggttt tggtacaggt
     2821 ggttggcagt tggctgctct acgctggtgt gccaaggctg cgcgtaaacc gattatcgct
     2881 gatggaggaa ttcgtactca cggtgatatt gctaagtcta tccgcttcgg tgctagcatg
     2941 atcatgattg gttccctctt tgcaggacac attgaaagtc cagggaaaac gattgaagtc
     3001 gatggtgaac agttcaaaga atattatggt tcagcctcac aatatcaaaa aggtgcttac
     3061 aaaaatgtgg aaggcaaacg tatcttgctt cctgctaaag gtcatctgca agacacttta
     3121 actgagatgg aacaagacct tcaaagtgct atttcttatg caggtggacg tcaggttgct
     3181 gaccttaaac acgttgatta tgtgatcgtg aaaaactcca tctggaatgg ggatgcttcc
     3241 cactaagacg gggtctttga ccaaaaaact tgttattaga gcaaatttct gttataataa
     3301 aacaagtttc cacccttagt gtaatggata tcacgtaaga ttccggttct tgagatgggg
     3361 gttcgattcc ctcagggtgg atgtaaacat cctaaaaagc ctttaatagg gcttttttct
     3421 ttatcctgac ccaaatttgc cgctaaaact gagaatctct gtctaaagaa ttcccaaatg
     3481 ctttccagtc ccgttttaga gtgactcagg gggctttttt tgatataata aaaaggactg
     3541 ttatcagtta gaaagaggtt ggtatgaaag aattacaaac tgtactaaag aatcattttg
     3601 caatcgaatt tgcagacaaa aatttactgg aaactgcctt tactcatacg agttatgcca
     3661 atgagcaccg cctcttaaaa atttcacaca atgaacgctt ggaattttta ggagacgctg
     3721 ttctacagtt attgatttca gaatatctat ataaaaaata tcctaaaaag cctgaaggtg
     3781 acctatcaaa actccgtgct atgattgtcc gtgaggagag tttagctggt tttgcgcgtg
     3841 attgccagtt tgaccagttt atcaagttgg gtaaagggga agaaaaatca ggtggtcgca
     3901 atcgtgacac cattcttggt gatgcctttg aagcctttct tggtgccctt cttttggata
     3961 aggatgtggc caaggtcaag gaatttatct atcaagtcat gattcctaag gttgaagcag
     4021 gcgaatttga gatgattaca gactataaaa cccatctcca agagttactt caggtcaatg
     4081 gtgatgtggc tattcgttat caggtgattt ctgaaacagg gcctgctcac gataaggtct
     4141 ttgatgtaga agttcttgtt gaaggtaaga gcatcggtca aggccaaggt cgttctaaga
     4201 aattagcaga gcaggaagct gccaaaaatg ccgttgagaa ggggctggat tcatgtattt
     4261 aaaggaaatc gaaattcagg ggttcaagtc ttttgctgat aagaccaagg tcgtttttga
     4321 ccaaggtgtg acggcagttg ttggacccaa tggatctgga aagtccaata ttacagaaag
     4381 tctgcgttgg gctttggggg agtctagtgt caagagtctc cgtgggggca agatgccgga
     4441 tgtcatcttt gctggaacag aaagtcgcaa accgctcaat tatgcttctg tagttgtgac
     4501 tctggataat catgacggat ttatcaagga tgcaggtcaa gaaatcaggg tggaacgcca
     4561 tatctatcgt agtggagata gcgaatacaa gattgacggc aagaaagtcc gtctgcgtga
     4621 tattcatgac cttttcttgg atacaggttt gggacgagat tccttctcta ttatttccca
     4681 agggaaggtt gaggagattt ttaattccaa gtctgaggaa cgacgagcta tttttgaaga
     4741 agctgctgga gttttaaaat acaagactcg cagaaaagaa accgagagta aactgcagca
     4801 aactcaggat aatctggacc gcttagagga cattatctac gagttggata atcaaatcaa
     4861 gcctcttgag aagcaagctg agaatgcccg taaatttcta gacttagaag gtcaacgcaa
     4921 ggctatttac ttggatgtat tggttgctca aatcaaggaa aataaggcag aactagagtc
     4981 gacagaagaa gagttggctc aggttcaaga actcttgatg agttattacc aaaagcgtga
     5041 aaaattagaa gaagaaaatc aaactcttaa aaagcaacgc caagatttac aggctgaaat
     5101 ggccaaagac caaggcagtt tgatggactt gactagtctg attagtgatt tagaaagaaa
     5161 attagcccta tcgaaactgg agtctgagca agtggccttg aatcaacagg aggcacaagc
     5221 tcgtttggct gctttggagg ataagagaaa ttcactcagc aaagaaaagt ctgataaaga
     5281 aagctcttta gctctgttag agggaaatct agtccaaaat aatcaaaaac tcaatcgttt
     5341 agaagctgaa ttgctggctt tctcagacga tcctgatcag atgattgagc tcttacgtga
     5401 acgctttgta gctcttttac aagaagaagc ggatgtctca aaccagttga cccgtattga
     5461 gaatgagttg gaaaatagtc gtcagctttc tcaaaaacaa gcagatcaac tagaaaagct
     5521 gaaagagcaa ttagctatag ctaaagagaa ggctagtcag caaaaggaag agcttgaaac
     5581 tgccaaggag caggttcaga aattattggc tgactaccaa gctattgcca aggagcaaga
     5641 ggagcagaaa acttcctatc aagctcaaca aagccaactc tttgaccgtc tggataatct
     5701 caaaaacaag caggccagag ctcaaagttt ggaaaatatc ctgagaaatc atagtaactt
     5761 ttatgcaggt gttaagagtg ttctccaaga aaaagatcgc ctaggtggga ttattggtgc
     5821 agtcagtgag catctgacct ttgatatgca ttatcaaact gccctagaaa ttgcgcttgg
     5881 agcgagtagc caacatatca tcgtagaaga tgaagagtcg gcaaccaagg ctattgactt
     5941 ccttaaacgg aacagagccg gtcgtgcaac ctttcttcct ttgaccacta tcaaggcgcg
     6001 tacgatttct agtcagaacc aagatgctat cactgtaagc ccaggtttcc ttgggatggc
     6061 agatgagttg gtgacttttg atactagact ggaagccatt ttcaagaact tgctagctac
     6121 gacggctatc tttgatgccg tagaacatgc gcgtgcagca gctcgccaag ttcgttatca
     6181 ggttcgtatg gtgacattgg atgggacaga attacgcacg ggtggttcct atgcgggtgg
     6241 tgccaatcgc caaaataaca gtattttcat caagccagaa ctggagcaat tacaaaaaga
     6301 aattgctgca gatgaagcaa gcttgcgttc agaagaagcg gctttgaaga ccttacaaga
     6361 ccagatggct acattgacag aaagattaga agtcatcaaa tctcaaggag aacaggcacg
     6421 tattcaggag caaggcttgt ccctcgctta tcagcaaact agtcagcaag ttgaagaact
     6481 ggaaactctt tggaaactcc aagaagagga aatagatcgt ctttccgagg gagattggca
     6541 agcggataag gaaaaatgcc aagatcgtct tgctgcaatc gccagtgaca agcaaaatct
     6601 ggaagctgag attgaagaga ttaagtctaa caaaaatgcc atccaagaac gctatcaaaa
     6661 cttgcaggaa gagctagcgc aagctcgttt gcttaagaca gaactgcaag ggcaaaaacg
     6721 ttatgaagtt gctgatattg aacgcttagg caaggaattg gacaatcttg attttgaaca
     6781 agaggaaatc cagcgccttc ttcaagaaaa ggttgataat cttgagaagg ttgatacaga
     6841 attgctcagt caacaggcgg aagaagccaa aactcagaaa acaaatctcc aacaaggttt
     6901 gattcgcaag cagtttgagt tggatgatat tgaaggtcaa ctggatgata ttgctagtca
     6961 tttggatcag gctcgccaac agaatgaaga gtggattcgc aagcaaacac gtgctgaagc
     7021 caagaaagaa aaggtcagcg agcgcttgcg ctatttacaa agtcaattaa cagaccaata
     7081 tcagattagc tatactgaag ctctagaaaa ggcgcatgaa ttggaaaacc tcaatctggc
     7141 agagcaagag gtgcaggatt tagagaaagc tattcgctca ctggggcctg tcaatataga
     7201 agctattgac cagtacgaag aagttcacaa tcgtctggat ttcctaaata gccaacgaga
     7261 tgatattttg tcagcgaaaa atctgctcct tgagaccatt acagagatga atgatgaggt
     7321 caaagatcgc tttaaatcaa cctttgaggc cattcgtgaa tcctttaaag tgaccttcaa
     7381 acagatgttt ggaggaggtc aggcagactt aatcttgact gagggagact tgttgacagc
     7441 tggggttgag atttctgttc aacctccagg taagaaaatc cagtcgctta acctcatgag
     7501 tggtggtgaa aaagccttat cagctcttgc tttgcttttt tctatcattc gagttaagac
     7561 tatcccattt gtcatcttgg atgaggtaga ggccgcgctg gacgaagcca atgttaaacg
     7621 ttttggggat tacctcaatc gatttgacaa ggacagccag tttatcgtcg taacccaccg
     7681 taagggaacc atggcagcgg ctgattctat ctatggagtg accatgcaag aatcgggggt
     7741 ctcaaaaatt gtttcggtta agttaaaaga tttagaaagt attgaaggat gacaattaaa
     7801 ctagtagcaa cggatatgga cggaaccttc ctagatggga atggacgctt tgatatggat
     7861 cgtctcaagt ctctcttggc ttcctacaag gaaaaaggga tttactttgc ggtggcttcg
     7921 ggtcggggat ttctgtctct ggaaaaatta tttgctggtg ttcgtgatga cattattttc
     7981 atcgcggaaa atggcagttt ggtagagtat caaggtcagg acttgtatga agcgactatg
     8041 tctcgtgact tttatctggc aacttttgaa aagctgaaaa cgtcacctta tgtagatatc
     8101 aataaactgc tcttgacggg taagaagggt tcatatgttc tagatacggt tgatgagacc
     8161 tatttgaaag tgagtcagca ttataatgaa aatatccaaa aagtagcgag tttggaagat
     8221 atcacagatg acattttcaa atttacaacc aacttcacag aagaaacgct ggaagctgga
     8281 gaaacttggg taaacgataa tgtccctggt gtcaaggcta tgacaactgg ctttgaatct
     8341 attgatattg ttctggacta tgtcgataag ggagtggcta ttgttgaatt agctaaaaaa
     8401 cttggtatca caatggatca ggtcatggct tttggagaca atcttaatga cttacatatg
     8461 atgcaggttg tgggacatcc tgtagctcct gaaaatgcac gacctgaaat tttagaatta
     8521 gcaaagactg tgattggtca ccataaggac cagtcggtta tagcttatat ggagggctta
     8581 taatggcaga tataaaatta atcgcattgg acttggatgg taccttgctg actactgata
     8641 aaaggctgac ggatcgcacc aaggcaactt tgaaagctgc gagtgatcgt ggtatcaagg
     8701 tcgtattgac aactggtcgt cccttaaaag ccatggactt ctttctccat gagttaggga
     8761 ctgacggcca tgaagatgag tataccatta cttttaatgg tggattagtt cagaaaaata
     8821 caggagaaat ccttgataaa acagtctttt catatgatga tgtggcacgt ttgtatgagg
     8881 aaacagagaa attatcactg cctcttgatg ccatctcaga aggaacagtt tatcaaatcc
     8941 aatcggacca agaaagtctt tatgccaaat tcaatccagc tttgactttt gttccagttg
     9001 actttgaaga cctgtctagt caaatgacct acaacaaatg cgtgactgcc tttgctcaag
     9061 aacccttgga tgcagccatt cagaagattt ctccagaatt gtttgaccaa tatgaaatct
     9121 ttaaatcacg tgaaatgttg ctagaatggt caccaaagaa tgttcataaa gcaacaggtt
     9181 tggcaaaact aattagccat cttggaattg atcaaagtca agtgatggcc tgtggtgacg
     9241 aggccaatga cctctctatg attgaatggg cagggctcgg tgttgccatg caaaacgctg
     9301 ttcctgaagt aaaggcagcc gcaaatgtag tgacgccgat gaccaacgat gaggaagctg
     9361 tcgcctgggc tatcgaagaa tatgtgctaa aggagaacta agatatggga ttatttgacc
     9421 gtctattcgg aaaaaaagaa gaacctaaaa tcgaagaagt tgtaaaagaa gctctggaaa
     9481 atcttgattt gtctgaagat gttgatccta ccttcacaga agttgaagaa gtttctcaag
     9541 aagaagctgt gcttgaagaa agtcaggatt cagagccagc tgtaggggtt tctcaagaag
     9601 aaatagaaga attaccagag gaagagaagc ttgagcacga aggaactata gaagaaaata
     9661 attctgaagt tcttgaagca gaaaggcctc aaacagaaga aactgttcag gaaaaatatg
     9721 accgcagtct taagaaaact cgcacaggtt tcggtgcccg cttgaatgcc ttctttgcta
     9781 acttccgctc tgttgacgaa gaatttttcg aggaactgga agaactgttg attatgagtg
     9841 atgttggtgt ccaagtcgct tctaacttaa cggaggaact acgttacgaa gccaagcttg
     9901 aaaatgccaa gaaacctgat gcacttcgtc gtgtcatcat tgagaaattg gttgagcttt
     9961 atgaaaagga tggtagctac gatgaaagca tccacttcca agataacttg acagttatgc
    10021 tctttgttgg tgtgaatggt gttgggaaaa caacttctat cggaaaacta gcccaccgct
    10081 acaaacgagc tggtaagaag gtcatgctgg ttgcagcaga taccttccgt gcgggtgcag
    10141 tagctcagct agctgaatgg ggccgacgag tagatgttcc agtagtaact ggacctgaaa
    10201 aagctgatcc agccagcgtg gtctttgatg gtatggaacg tgccgtggct gaaggtatcg
    10261 atattctcat gattgatact gctggtcgtc tgcaaaataa ggataacctt atgactgagt
    10321 tggaaaagat tggtcgtatt atcaaacgtg ttgtgccaga agcaccacat gaaaccttct
    10381 tggcacttga tgcatcaaca ggtcaaaatg ccctagtaca ggccaaagaa ttttcgaaaa
    10441 tcacaccttt aacgggaatt gttttgacta agattgatgg aactgctcga ggaggtgtgg
    10501 ttctagccat tcgtgaagaa ctcaatattc ctgtaaaatt gattggtttt ggtgaaaaaa
    10561 tcgatgatat tggagagttt aactcagaaa acttcatgaa aggtctcttg gaaggtttaa
    10621 tctaatcaga agcaaaaatc ctgcaaggca taaacttgca ggaaattttt ttattcgaaa
    10681 cgaccatctt gacgataggc gatatctggt tgccaagtcc atttggcacc gaatttttca
    10741 agtaggtcaa agctggcttg aggtcccatg cttccagctt tatagtcatg aagtggggca
    10801 ccattttcag cccagagctc ttcaatacgg tcaatcaact tccatgatgc accaacttca
    10861 tcccagtggc taaagttagt tgagttgtta tttaggacat cataaatcaa tttctcgtat
    10921 ggttctggag aagcaccagt tgcagtcgca tctgtacggt aatcaagtga gttaggagcc
    10981 aagttaaatt cttctcctac ttgcttccca tttaggctaa gagagaagcc ttctgttggt
    11041 tgaatataga tggtcaaaat atttggagca agtggttctc caaagataga atccatttgt
    11101 ttaaagacga tgttgacatg agttcctttt tcagtcagtc gtttacctgt acggaaaaag
    11161 aaaggaacac tacggaatcg atcgctgtct acaaagaagg caccagatgt aaaggtttca
    11221 gttgttgatt ctggattcac atttggctcg ctacgataag agatgtattt catgccatca
    11281 atcttaccag agcggtattg cccacggata aagtgttctt tgagttcttc atcagttgga
    11341 tgatagaggt ttttaaagac cttaatcttt tcagcacgaa tctcgtcttt tgtgaagatt
    11401 gctggtttgt ccatggcgag gagcgaaaga agttgtagag tgtggttttg gaccatgtca
    11461 cggagggcac cggattggtc atagtagcca ccacgttctt ctacacccaa gcgctccgca
    11521 aaggtaattt gaacattgtc gataaaatcc ttgttccaaa cgttttcaaa aatcaagttt
    11581 gcaaagcgaa ctgcaaagat gctttggatc atttccttac caagataatg gtcgatacgg
    11641 aaaatttgtt cttcgtcaaa tgttgctagg agttcgtcat tcaacttgct tgcagttgcg
    11701 taatctgtac caaatggttt ttcaacgatc aagcgctcaa aacctttgcc atcgacaatg
    11761 ttttcagatt tgaggtgttt ggcaatggtt ccaaagaact gaggtgccat agacaagaag
    11821 aagagcttat tgtgttcagc ttggtatttt tcattaagct cagcttgtaa ttgacgcaaa
    11881 gcaatataat gttccgaatc attgacatca tggctttgat agtagaagtg gctagcaaat
    11941 tcttgggctt gctcggtact atctgccaaa tcaaggatgg actcgacaac tacagattca
    12001 aaatattcct tactccaagg tctacgggca gttccaataa cggcaaagtg cttggaaaga
    12061 ttgccggatt gatatagtct aaaaagggaa gggtagagct tgcgtttagc caggtctcca
    12121 ctcgcaccga aaattgtaac aataacctta gatgacatct agctacctaa tttctatttt
    12181 tattcctagt cttgctaggt atgaggaaac ctcatttcat aaacttaatt ctaacataat
    12241 tttccgaaaa atcaaaaatt ccaatacgag gtagaaaaac tgcaaggaaa tccttacagt
    12301 ttgagtttag acgtttaaga ccttatctaa gaactctttc agacgagggt gttgtgggtt
    12361 atcaaagatt tggtcaggtg ttccgtcttc aaggaactcg ccatctgcag taaagataac
    12421 gcggttggca acctgacgag caaatcccat ctcatgggtt acgataatca tggtcatgcc
    12481 ttgctcagcc aattccttca taacgttaag tacgtctcca accatctcag ggtcaagggc
    12541 agaagttggt tcatcgaaga gcatgatgtc tggattcatt gctaggccac gagcgatggc
    12601 cacacgttgt ttttgaccac ctgataggtt atctggattg gcattagctt tatctgctag
    12661 tccaaccttt tcaagcaact ccattcccaa ttcctcagct tcttccttag tcatcaactt
    12721 gtgctcaata ggagcaaagg tgatgttgtc caatacagac atatgaggga agaggttgaa
    12781 gtgttggaat accatgccga tattttcacg gacgtggtca acattggttg ttttttcagt
    12841 taaatcatag ccgttcacag tgatgtgacc gctagtgact tcttctaaaa gattgaggct
    12901 acggaggaaa gttgacttac cagaacctga aggaccgatg atacaaacaa catctccttc
    12961 atagaactta gtcgtaattc cttttaggac ttcatttttt ccatagtgct tgtgtaaatc
    13021 atttacatca atttttaatt ttgccattaa cgaatcctct tttctaagcg tttcgctagt
    13081 ctagtcaaaa gtgtgataat tacaagatag aagatagcaa ggattgcata catcttgaaa
    13141 ctttggtagt tacgagcaat gataatctta ccagtttgga agagttcaac caaaccgata
    13201 gcagatacga tagttgtatc tttaagagcg ataacgaatt ggttgacaaa gtttggcaac
    13261 atcaatttag ttgcttgtgg caagataatc ttacgcatgg tttttccata agagataccc
    13321 aagcttcggc tggcttccat ttggccaact ggaacggcct gaataccacc acgaacgatt
    13381 tcagcgatat aagcagccgc attgagtgag agggcaatgg ttccagctac aaagtcgtta
    13441 attgggcttt gttggcctgt gatagactcg atgaagtttg gaattcccca gaagatgaag
    13501 gctgcaagaa tcatcaatgg aataccacga ataacgtcaa cgaaaatctc agagatgacg
    13561 cgaagagatt tgtatgggct aacgctaaac ataccgaaga taattccgat gacaatggca
    13621 atagcaaatg agataagagc tagagcaaga gtgataccaa gaccgctaag gagttgtttg
    13681 tagttgtttt gaagcaagcc ccagagcgtt gtttcgtcaa cagtacttgt tgaagcagtt
    13741 gaagattcgc tagctaggta tttgtcaaga atcttttgga attcaccgtt tgctttaagg
    13801 tttgcaagtc cgttgttgaa catttcaatc agttctggat ttgctccttt tttaacggca
    13861 aaggctgttt caccgattgg agttccagag attggagttt tcaatttttg accttggctg
    13921 atagaatatt tgagaacagg ttcatcatcc ataacggcat caatggcacc agtgtttaaa
    13981 ctgtcataca ttgaagaacc atcagcaaag gttttgattt tgtaaccgta tttgctttga
    14041 ttttctgtta ggaaggtttg agaagcagtt ccgtttttaa caccgactgt ctttcctttt
    14101 agatcttcat aagaagcaat attgcttgat tctttgacac caagaatggt attagcagtg
    14161 tagtatgatt ctgagaagtc aaaagttgcc ttacgagcat ctgtgacaga cataccagca
    14221 atgataccat cggcttgacc agcttggaca gcactgatag cagcatcaaa accagggttg
    14281 gtgatttcaa tttcaaaacc ttggtcttta gcgattgcct taatcaattc catatcaata
    14341 ccagtgtatt ggttgcttga attttggaaa acaaaaggtg caaaagaaga atcgctggca
    14401 atgatatatt tagccttaac aggaatagct tttaatcctg cgagagtagt tgtagttggc
    14461 actgctgaag atgatgaagc agtccatttc ttgataattt tatcaagact accatctttt
    14521 ttcatttcag ccaaggcttg gttaaattca gtaaccaggt gctcgtattt acttcctttt
    14581 ttcacaccga aagcaaaact tcctacagct tcaccatcca tttcaatatg gaggtcttga
    14641 ccttggttaa tggcatattc gataacaggt ttgtcatcca tcatggcatc gatggcacca
    14701 gcactcaagc tgttgttcat taaatcacca gtgtcaaatg ttttaatagt aaagccgtat
    14761 ttatctttga ttgtttcaag gaaacgttga gcggcagttc cgtttttaac accaacggtt
    14821 ttgccagtta attggtcgta cttgctaatt ttgtgtgact ttgtagtagc aatgacaact
    14881 tttgtatcat agtaagtatc agacatggtg aagacttttt cacgttcttt agtctttgtc
    14941 atccctgcca tgatagcgtc ggcttgccca gcttgaaccg cattgactgc tgcgtcaaat
    15001 ccaggatagg acatctgaat gttccagcct ttaatctcag cgactttgtt aataatgtca
    15061 acatcaattc ctttataagt ttgatctgaa tctttaaact caaaaggtgc ataggcggta
    15121 tcagaaacaa tcttaatcgt ttctgctttg gcaataccta atgagaaaat tgggaataaa
    15181 attagcaaaa atgctagaaa ttttttcttc atttttagtc tccttttccg aatattctct
    15241 cattatatca gaaaaagtaa aaaaaggcaa atttttatat ttttcgtgtc agaaaatata
    15301 acattgattt ttccttttct ttcttgaatt gctattaaaa attgctataa taatactata
    15361 tatagaagaa aagaggacgg ggatatgaag aacaaaagaa tatttaaaga cttccaagct
    15421 tcaaaaatga atttaaacct ttacacaagc cccttgttag cctttgtttt tgtcttcata
    15481 ggagagtttg tggcttatac tttatatggt attagtttgt tagctctcat cggacttgct
    15541 agaaattttg gagaggctgg tcaaaatctt gcaagctact tgcagacctt gcatcagagc
    15601 ttgacggata aaacaagtga ctttcgttta attttaggat tactggcctt tggttttatt
    15661 cttaacactg tgttcagatg gacaagaaaa gttgagaaaa gacctattcg aaccttggga
    15721 ttttatagag agaattgcct cagcaatctt ctgaaaggat ttagtctagg cctggcactt
    15781 tttcttctga ccttgttaag tttagtggtc ttaggtcaat atcgtttgga atccattcac
    15841 ttgaatcctt attatcttgc ctttgtcgtc tttactatcc cattttggat tttacagggg
    15901 acagcagaag aagtggtggc ccgtgcttgg ctacttcctc aattggcctc aagaaccaat
    15961 ctaaaactag ctattcttat atctagcctg ttctttaccc tgcttcatat gggcaattct
    16021 ggcctcaccc ctctatctct agtaaatctc tttttattcg gagttgccat ggctctttac
    16081 cttctcaaaa ctgatacagt ttggggtgtt gcaggtattc atggtgcttg gaattttgct
    16141 cagggtaatc tctttgggat tttagttagt ggtcaaccgt caggaacgtc tctgatgacc
    16201 tttttaccac aaggcaatca agattggcta tcaggtggtt cttttggcat agaaggttcc
    16261 attatgacaa gtctggtatt actactgctg attgtctatc ttgctaataa attaaagaaa
    16321 gaaaatgaaa ggatgtgact tcggtccgtc cttttcttcg tgaaaatact ataagtatgc
    16381 taaaatagga atagcacatg gagagaggat tcttatgatc aatcacatta cagataatca
    16441 atttaaacta gtatcaaaat atcaaccatc aggagatcaa ccccaagcta tcgagcagtt
    16501 ggtggataac attgaggggg gagaaaaagc tcagattctg atgggggcga ctggaacagg
    16561 gaagacctat actatgagtc aggtcatttc taaagtcaat aaaccaactc tggttattgc
    16621 ccacaataaa actctggctg gtcagctcta tggggagttt aaggaatttt tccctgaaaa
    16681 tgcagttgag tatttcgtat cctactatga ttattaccag ccagaggcct atgtcccttc
    16741 tagcgatacc tatattgaga aggatagttc tgtcaatgac gagattgaca agcttcgcca
    16801 ctcagctacc tcagcccttt tggagcgtaa tgatgttatt gtcgtggcct cagtctcttg
    16861 tatctatggt ttgggttcgc ccaaggaata cgctgatagt gtcgttagtc tccgtcctgg
    16921 tctagagatt tctcgtgata aactcttgaa tgacttggtc gatattcagt ttgaacgcaa
    16981 tgatattgat ttccaacgcg gaagatttcg cgttcgtggg gatgtggtag agattttccc
    17041 agcttcccga gatgaacatg cctttcgagt agaatttttt ggagacgaaa ttgaccgtat
    17101 tcgtgaagtt gaggctctga caggtcaggt gttgggagaa gtggatcatt tagcgatttt
    17161 cccagcgaca cactttgtga ccaatgacga ccacatggaa gttgccattg caaagattca
    17221 ggccgagttg gaagaacaat tagctgtctt tgaaaaggaa ggtaaactgc ttgaagccca
    17281 gcgtttgaaa cagcggacag agtatgatat cgaaatgttg cgtgagatgg gctataccaa
    17341 tggggttgaa aattattctc gccacatgga tggacggagc gaaggagagc ctccttatac
    17401 gcttctcgac ttcttcccag atgatttctt gattatgatt gacgagagtc atatgaccat
    17461 agggcaaatc aagggcatgt acaatggaga ccgttcgcgt aaagaaatgc tggttaatta
    17521 tggtttccgt ttgccgtctg ctttggacaa tcgtcctctc cgtcgggagg agtttgagag
    17581 tcacgttcat cagattgttt acgtttcagc gacacctggt gactatgaaa atgaacagac
    17641 cgagacagtg attgagcaaa tcattcgtcc aacgggactc ttggatccag aggtggaagt
    17701 ccgtccgact atgggacaga ttgatgacct cttgggtgaa atcaatgccc gcgttgaaaa
    17761 aaatgagcgt acctttatca caactttgac caagaaaatg gcagaggact tgaccgacta
    17821 cttcaaggaa atgggtatca aggttaagta catgcactcg gatatcaaga ccttggaacg
    17881 gacggagatt atccgtgacc tgcgcttggg tgtctttgat gtcttggtcg gaattaacct
    17941 gctccgtgaa ggaattgacg ttcctgaagt gagcctcgta gctattctcg atgctgacaa
    18001 ggaaggtttc cttcgcaacg aacgtggact catccagact attggacgtg ctgctcgtaa
    18061 cagtgaaggc catgtcatca tgtatgcaga cacggttacc cagtctatgc aacgtgctat
    18121 cgatgaaact gcccgccgtc ggaaaattca gatggcctat aatgaagagc atggtatcgt
    18181 accacagaca atcaagaaag aaatccgtga cctgattgct gtgaccaagg cagttgctaa
    18241 ggaagaggac aaggaagtcg acatcaatag cctcaacaaa caagagcgca aagaactcgt
    18301 caagaaacta gaaaaacaaa tgcaagaagc cgtcgaagta cttgactttg aactggcggc
    18361 tcagatccgt gatatgatgt tggaagtcaa ggccttggat taggggaata gtatgattta
    18421 tttaagaaag ttaaagagag aagatttgat gtctttatgg gaaatggctt attcacaact
    18481 taatccagtt tggaaacagt atgatgctcc ctattatgat gattatcagt atttttcaaa
    18541 ttttaaagaa ttcgaactac aaaaatcaga atccatttta agcaactcaa atcgccttgg
    18601 tatttttgtt gatgataaac tagttgggac tgtttcgcgt tattgggtat gtaaacaaac
    18661 aagatggatg gaattgggaa ttggtattta tgataaaaaa ttctggaaca ctggtattgg
    18721 gaaagttgct atgttgcagt ggatagatag gacgtttcag gattacttgg agttggagca
    18781 tctgggtttg acaacttggt cagggaatct tggtatgatg aaacttgctg aaaaattaag
    18841 aatgaaaaaa gaagctcata ttccaaaagt tcgttattat caaggtaaat attttgatag
    18901 tattaaatat ggtattttga gagaagactg ggagaaaaca aatgacggtt attatcaaat
    18961 caatggaaac tcctgaagag atagaaggta agccccttgt tcactggcaa acgtggagag
    19021 aggcttatga tggccttttg cctgcagaat ttcaggagac aatgacatta gaaagatgtc
    19081 gattctttag tcaaaagtat ccagaaaata cattgattgc gatggatggt atgaaggtag
    19141 ttggttttat cagttatggc aactttcgtg atgagactat tcaagctggc gaaattattg
    19201 ctttatatgt tttaaaagac tattatggaa aaggtatcgc acaaaagtta ataaaagcag
    19261 ctttgattgc tcttaatcat ttttctgaaa ttttcttatg ggtattgaaa gataataagc
    19321 gcgcaattgc tttctatcaa aaaatgggct ttacttttga tgaacaagaa aagatacttg
    19381 aacttggaaa gcccataaag gaaaaacgga tggtattcta ttctaaataa ttttaaaaag
    19441 tagaagctaa tggtactggt atcaagtcta aaaatttaat aaattagaaa gtgagtaaat
    19501 ttatgtctcg agcacaatta acgattttaa caaatatttg tctgattgaa gatctcgaag
    19561 ctcagcgcgt ggtgatgcag tatcgcgctc ctgaaactaa tcgctggtct ggttatgcct
    19621 ttccaggagg ccatgtagaa aatggcgaat ctttcgcaga gtctgtcatt cgtgaaatct
    19681 atgaagaaac agggttgact atccaaaatc ctcaacttgt cggcattaaa aattggccac
    19741 tagatacagg tgggcgctat attgtcgttt gttataaggc aactgagttc tctggtaccc
    19801 ttcgctcttc agatgaagga gaagtttctt gggtgcaaaa agaccagatt ccaaacttgg
    19861 atctggccta tgatatgcta cctttgatgg agatgatgga agcatcggac aaatctgaat
    19921 ttttctaccc tcgccgtaca gaagacgatt gggaaaagaa aattttctaa tcctttacta
    19981 aataacctag ctgatccaag gcctcctcga tatagtggag gtcttgttgt gtttcggctt
    20041 cgactaggtg gtaatggaca ccatctgtca attcagataa aggtttaaaa tcagaatgct
    20101 cgacttgttc tagaaaatgt tgaacgtctc ggcggcaaga cagtttaagc aaggtttcaa
    20161 tttctccata aacgggatgg tcaatcaaag tattctggac atgcccacca ttatcgacaa
    20221 tagcaaggag ttcctgaccg atttcttcaa cttcatgttt cactttgaaa agtttgtgaa
    20281 cataaggatt ggtatcaatt tgcttataga tgtagccacg attggtggat aggataggag
    20341 cgccatcggc tctcaaaatt gcaatgtcct gcacaatgac ctgacgtgtg acatgaaaat
    20401 gttccgccaa actttggcca ttaagggctt taggagcttc tttcaagagt tggagcaggg
    20461 cttgtttgcg atcttttgtc atagcttttc cttttaacgg cgttttcgaa gcactttata
    20521 gacagctagt gctaatgtat agtctaccat actatggata attgtgccaa atccaactag
    20581 tacaaataga acatagaaca tgttttctac attggtaccc gaagttgcgt aaaaaaggac
    20641 acaggctaat acttcagcaa gggcatgaac aacagccaaa acaaaattga aaacccagga
    20701 agattttggt ttatctaggg tatcggggaa tttttgtagg taaagagatc ctaaagcacc
    20761 aaaagatata tgggaaaaag cccgaaaaac tataaccatg ggatagccag ccatcaaaaa
    20821 tccaaaacta gaggctagga tgacaaaaac tgccatcaag ggcgacaaga acatggctat
    20881 aaaaatagcg atgtggctcc ccaaagtata ggaagcaggt ggaatgacaa tcttgaaagg
    20941 cataacaatt ggaatcaaaa tcgcaatagc cgttaaaagg gctgtcattg tcataaattg
    21001 tgtctttttc cgtgtattca caagaatctc ctttttaact gcatatacac tagtatggta
    21061 caataaacca gacaataaag caagaattta cttgggttta tagatcattt tttagttaaa
    21121 agttatagta gatggaaact agaatagtcc acctctactt ctaaaacatt gttagcgatt
    21181 tgactgtcct gatcgatttg tcctgttctt atttcgtttt actatagtaa agatttcatt
    21241 aaaaagaaac tgtatagagc aaaatctcca ccttcaggtt tgaaagcgga gattgttttt
    21301 attttttcaa ggtttgtagt cgtggaacaa tggctagggt tagaattgca gaaatgacca
    21361 attcagcaat tgaatttgtt gagataacgg ttgccagaag aagttggata tttccattat
    21421 aaacatttcc aaataggaag aagattcctc caaggacaaa gatagtattt gtcaaggaac
    21481 caagggctcc agctaaaatc agaccagtct tgtttttcat cagtttatag actaagtaag
    21541 gagttaaacc aatcaaaata cgtgggacga tggcaatgat agctgagtag atgtttccgt
    21601 ttggtacgaa gggagagaag aggtagcttg tcggtagaat cgtaatcgtg ttaaccgtca
    21661 agctaagtaa tcccatcaaa aatccaagtg taaccccaac tcgtggacca taaataatgc
    21721 tggcaataat gacaggaata tgaacaatgg tcggtttgat tggaaatgga aaaaggttaa
    21781 agataagtga gctcagaaag tgtatcacga gcatggtagc aaaaaagata gcaatgggtg
    21841 caatattaga gcgttttttc atcgatagtt tcctttattc tttctaaaat aattgtgagg
    21901 tcagctaaag ctcctcgtcc gtggtctcca caagctagta gggattcctt aggagcaatc
    21961 agctgatagc cgtaggtttc taatgttttc agattattct gagttactgg atggtcatac
    22021 atttttgtat tcatagcagg agctattagt ttgggaatat gacttggtag ggctagagct
    22081 gtactggtta ccatgttgtc cgcaaatccg tgagctagtt ttgcaatagt gttagcagtt
    22141 gcaggtacca cgataaataa atctgctttt tttccaagtt cgatatgatt gacctgatca
    22201 ggatagggtt ccttcatgac atccaagtgg acaggattct gtgagagtac ctgtagtgtc
    22261 aaaggttgga taaactctgt agcagcctga gtcattaaga cagtgacttg atggccttgt
    22321 ttttttagag aactgactaa atctgccgac ttataagagg cgattgaacc cgttacagcc
    22381 aagagaatgt ttgccatagt tttcctttct aagaatgata ggcttgaatt ttttcaagga
    22441 ggagttctgc aatttcttct ttagtctgga ctgtttgaag ctgatttttc tcaacaaata
    22501 tagctcggtg ctgatctgct gaaatttgag tcaggtcatt cgcgatgatt aaatctgctt
    22561 gattcttgat aagacttttt cgtgcaatgt caaccagatg atcttcggta acatcaacca
    22621 gcagtttgaa accaatcaga tgaatagtgg gattccattc cttgactagg gatatgattt
    22681 tgggtgtctt tttaaggaac aaaacctgaa cctcatcagt tgaagaaatc ttggcctgat
    22741 gattctgctt gcttaaaaat tcttttagat tggagctagc ctgaacttcc tcaagccctg
    22801 tcatataaac aggagtgtag tcagaaacag ccattgagtg gatcaagacc tgataatcct
    22861 gaacacgttc ttgcatttct attagaaggt ccttggtatt ggtaatttct cgaatactta
    22921 ggttaggatg aggctctggc ttcagagctc gttttgtcgt aattaaacaa acttcatgcc
    22981 ctgcagaaag caaagtctct gtgataattt tccccaagtg acctgtagaa tggttagtga
    23041 tagagcggac gctatcgata gcttcactgg taccgcccga tgtaactaaa attttcatag
    23101 cactattgta cacaaaaata agcggtaagt aaaatgaaag tgataaattt ttggtaaaaa
    23161 cgaagattta ctatagtttc aaactataaa gccatataaa atttaagaaa ggactctaaa
    23221 agccttaaaa acagagatat ttacgaacgt ttagagagtt ttaggatgtt aaaaatcttg
    23281 ttttgtgata taatgaatta tcatataaga ggttagagga attttgaatg aaaacagata
    23341 ttgaaatcgc acagagtatt gagttgaagc caattgttga tgttgtagag aaacttggta
    23401 tttcttatga cgatttggag ttgtacggaa agtacaaggc taaactcagc tttgataaaa
    23461 ttcgtgcagt tgagagcaat ccagtcggta aattgatctt ggttactgcc atcaacccaa
    23521 cacctgcagg tgaaggaaag tcgacgctta ccattggtct tgcggatgcc ttgaacaaga
    23581 ttggcaagaa aaccatgatt gctatccgcg aaccgtctct tggtccagtc atggggatca
    23641 agggtggtgc tgctggtggt gggtatgcac aagttctgcc aatggaagac atcaacctcc
    23701 actttactgg agatatgcat gctattacaa ctgccaacaa tgccctttct gccttgattg
    23761 acaaccactt gcaccaaggg aatgagctgg aaattgatca acgtcgtatc ctctggaaac
    23821 gcgttgtgga cttgaacgac cgtgcgctcc gccatgtgac tgttggtctt ggtggtcctc
    23881 taaacggtat tccacgtgag gatggttttg atattacagt tgcttcagaa atcatggcaa
    23941 ttctttgctt ggcaacggac atcgaggact tgaaacgtcg tttggcgaat atcgttattg
    24001 gttatcgcta tgaccgtacg cctgtttctg taggtgattt gcaggttgag ggtgccttgg
    24061 ctttgatttt gaaggatgct attaagccaa acttggttca gacaatttac ggtacacctg
    24121 cctttgtaca cggtggtcca tttgccaata tcgctcatgg ctgtaactct gttttggcga
    24181 cgacaacagc ccttcacttg gctgattaca ctgttactga agctggtttt ggtgcggacc
    24241 ttggtgctga gaaattcctt gatatcaaga caccaaactt gccaacatct ccagatgcag
    24301 ttgtcattgt cgcaaccctt cgtgccctta agatgaatgg tggtgtggct aaagacgctc
    24361 tgactgaaga aaatgtagag gcagttcgtg caggttttgc taacttgaaa cgccacgttg
    24421 aaaatatccg taagttcggt attccagcag ttgtagctat taacgaattt gtatctgata
    24481 cagaagctga aattgcagtc ttaaaagaac tctgtgcctc aatcgatgta ccagttgaat
    24541 tggctagtgt ctgggctgat ggagcagaag gtggagtagc acttgccgaa acagttgtta
    24601 agacaattgc tgaaaatcca gctaactata aacgtttgta cgataatgcc ctttctgtcc
    24661 aagaaaagat tgaaaaaatt gtcactgaaa tctatcgtgg tagcaaagtg aactttgaga
    24721 agaaagctca aacacaaatt gctcaaatcg ttcaaaacgg ttgggacaaa ttgccaatct
    24781 gtatggctaa aactcaatac agtttctcag acaatccaaa tgcgcttgga gcaccagaaa
    24841 actttgaaat taccattcgt gaattggtac caaaattagg tgcaggcttc atcgttgcct
    24901 taactggtga tgttatgacc atgccaggtc ttccaaaacg tccagcagct ctcaacatgg
    24961 atgttgaaag cgatggaact gtactaggct tgttctagtg gattgaaatt gactttaagt
    25021 gagtttggaa ataatatcca agctcatttt ttctcagact gcaagcagtt catcaataag
    25081 atttatactc ttcgaaaatc tcttcaaact acgtcagctt caccttgccg taggtatatg
    25141 atactgactc tgtcagttct atccacaacc tcaaaacagt gttttgagca acctgcggct
    25201 agcttcctag tttgctcttt gattttcatt gagtataagt agatagaaaa gttatatact
    25261 atctattgaa aatattataa atcagataca aagacaggtg aaaccttctg tgttatacta
    25321 gagatatgtt agatttgaaa gaatacggta tcgtcatgtg gccggaggag aaagtcattt
    25381 ctttccgtga gaaacttctc gcttggtatg atgaaaacaa aagagatttg ccttggagga
    25441 gaagtaaaaa tccttatcac atctgggtat ctgaaatcat gcttcagcag accagggtgg
    25501 atacagttat cccttactac gaaagattcc tggactggtt tccaactgtc gaaagtctgg
    25561 caactgcgcc tgaggagagt ttactgaaag cttgggaggg cttgggctat tattctcgag
    25621 ttcgcaatat gcaggctgca gcccagcaga ttatgactga ctttggtggc caatttccaa
    25681 atacctatga aggaatttcc agcttgaaag ggattggacc ttacacagca ggagccattt
    25741 ccagtattgc ttttaacttg cctgagccag ctgtagatgg taatgtcatg cgggtcttgg
    25801 cgcgtctgtt tgaagtcaac cacgatattg ggattccaag taatcgaaaa atttttcagg
    25861 caatgatgga gatcttgatt aatccggatc gtccgggtga ttttaatcaa gccttgatgg
    25921 acttagggtc tgatattgag tctcctgtaa atcccagacc tgaagaaagc ccagtcaagg
    25981 actttagtgc ggcatatcag aatggaacca tggaccgtta tccaattaaa tctcctaaga
    26041 aaaagccggt tcctatttat cttaaagcat tagttgtgaa aaattctcaa ggacaatttt
    26101 tacttgaaaa aaatgaaagc gaaaagctct tggcaggttt ttggcatttc ccccttatag
    26161 aagttgataa cttttcgcaa gaagagcagt ttgacctctt tcatcaggtt gcggaagaaa
    26221 gtgtgaactt tggccccagt ccagaagaga gtttccagca ggactatgac ctagatgttg
    26281 attggcttga tgtttgtttt gatacagtcc agcatgtttt tagtcatcga aaatggcatg
    26341 tacagattgt agcaggtcag gtgagtgact tccatgattt ttcagatagg gaagttcgtt
    26401 ggctttcacc agaagaattc aagaattacc cacttgccaa accccaacaa aaaatctggc
    26461 aggcttatgc acaagccaac ttagacagta gccaagacta gctattgtgt cttctgacta
    26521 ttttttggta taatagtaga gaaaaaggtg aacatatgaa aaaaatacta attgtagatg
    26581 atgagaaacc aatctcggat attatcaagt ttaatatgac caaggaaggt tacgaagttg
    26641 taactgcttt taatggtcgt gaagcgctag agcaatttga agcagagcaa ccagatatta
    26701 ttattctgga tttgatgctt ccagaaattg atggtttaga agttgctaag accattcgta
    26761 agacaagcag tgtgcccatt cttatgcttt cagccaaaga tagtgaattt gataaggtta
    26821 tcggtttgga acttggggca gatgactatg taacgaaacc cttctccaat cgtgagttgc
    26881 aggcgcgtgt taaagctctt ctgcgtcgtt ctcaacctat gccagtagat ggtcaggaag
    26941 cagatagtaa acctcaacct atccaaattg gggatttaga aattgttcca gacgcctacg
    27001 tggctaaaaa atatggcgaa gaactagact taacccatcg tgaatttgag cttttgtatc
    27061 atttagcatc gcatacaggt caagtcatca cgcgcgaaca cttgcttgag actgtctggg
    27121 gttatgacta ttttggtgat gtccgtacag ttgatgtgac tgtacgacgt ctgcgtgaga
    27181 agattgaaga tacgcccagc cgaccagagt atatcttgac gcgccgtggt gtagggtatt
    27241 acatgagaaa taatgcttga tttactgaaa caaaccattt ttaccagaga ttttatcttt
    27301 atcctgattt tgttaggttt catccttgtt gtgaccctct tattactgga aaatagacgt
    27361 gataatattc agttgaagca aatcaatcaa aaggttaaag atttgattgc aggagattat
    27421 tccaaggttc ttgatatgca aggtgggtct gaaatcacca atattaccaa taatttgaat
    27481 gacttgtcgg aggttattcg tctcactcag gaaaatctag aacaagagag taagaggcta
    27541 aatagtattc tgttttatat gacagatggg gttcttgcga ccaaccgtcg gggtcagatt
    27601 atcatgatta acgatacagc caagaagcaa ctggggttgg ttaaggaaga tgttctgaat
    27661 agaagcattt tggaattgct caagatagaa gaaaactatg aattgcgtga tttgattacc
    27721 caaagtccag aattgttgct agattcccaa gatatcaatg gcgaatattt gaaccttcga
    27781 gttcgctttg ccttgatacg tcgagagtct ggctttattt caggtttggt ggctgttttg
    27841 catgatacga cggagcagga gaaggaagaa cgcgaacgaa gactctttgt ttccaatgtt
    27901 agccatgagt tacggactcc tctgactagc gtaaaatcct atcttgaagc cttggatgag
    27961 ggggctttgt gtgaaactgt agcaccagac tttatcaagg tttctcttga tgagaccaac
    28021 cgtatgatgc gcatggtgac ggatctcctc catctttcac gtattgataa tgctaccagt
    28081 cacctagatg tggaactgat taacttcact gcttttatta cctttatcct caatcgtttt
    28141 gacaagatga aaggacagga aaaggagaaa aaatatgagt tggtgagaga ttatcccatc
    28201 aattctatct ggatggaaat tgatacagat aagatgacgc aggttgtcga caatatttta
    28261 aataatgcta ttaagtattc gccagatggg ggtaaaatca ctgtcagaat gaagacaact
    28321 gaagaccaga tgattttatc catttctgac cacggtttgg ggattcctaa gcaggattta
    28381 ccacgtatct ttgaccgttt ctatcgtgtg gatcgtgcta gaagtcgtgc acaaggtggt
    28441 acaggtctag gactgtctat cgctaaagaa attatcaaac aacataaggg ctttatttgg
    28501 gccaagagtg aatacggcaa gggttcaacc tttaccattg tgctccctta tgataaggat
    28561 gcagtgaaag aagaagtatg ggaggatgaa gtagaagact agaatgagtg aaataggctt
    28621 taaatacagt attttagcgt cgggttccag tggaaattct ttttatctgg aaacctcaaa
    28681 aaagaagctt ttagtagatg caggcttgtc tggcaagaaa attaccagtc tgctagctga
    28741 aattaaccgt aagccagaag acctggatgc catcttgatt acccatgagc attcagatca
    28801 tatccatgga gtaggcgttt tggctcgcaa gtatggtatg gatctttatg ccaatgaaaa
    28861 gacctggcaa gctatggaaa atagtaaata tcttggcaag gtggattctt cgcaaaagca
    28921 tatttttgaa atgggtaaaa ccaaaacctt tggagatatc gacatcgaga gttttggtgt
    28981 aagccatgat gcagtcgcac cgcagttcta tcgctttatg aaggatgata agagttttgt
    29041 cctcttgaca gatacaggtt atgtcagtga ccgtatggcg ggcattgtcg aaaatgcgga
    29101 tggttatctt atcgaggcca accatgatgt agagattttg cgatcaggtt cttacgcttg
    29161 gcgcctcaaa caacgaatcc tatctgacct tggtcacctt tctaacgagg acggtgctga
    29221 agctatgatt cggacgctag gaaatcgtac taagaagatt taccttgggc atttatctaa
    29281 ggaaaacaat atcaaggaac tggctcatat gaccatggtc aatcagctgg ctcaagctga
    29341 tctgggagtc ggagtagact ttaaggttta tgatacctca ccagataccg caacaccatt
    29401 gacagagata tagaaagaac gctgagaagg tgttcttttt atattgactg gacacctaaa
    29461 aagtaataca atggtgttac cattaaaaaa gggagcacaa aagatgacta ctattacatt
    29521 aaaagtttct gaagctgata aaacatttat gaaagcaatg gctaagtttg aaggagtttc
    29581 cctttcggaa cttattcgca ccaaaactct tgaagcccta gaagatgaat acgatgctcg
    29641 tgtggcagat ttagcctatc aagagtattt agaagacttg gaaaaaggag ttgaacccat
    29701 tacttgggaa gaaatgatgc atgatttagg cttgaaggat gaataatttg tataaattag
    29761 ttccaacaag acgttttatc aagcaattga aaaaattgga ccgttatacg cagaagctaa
    29821 ttacaaacta tttacaaacc aatgttttgg aagatccaag acgacacgga aaggctttgg
    29881 ttggtaatcg cgttggtcaa tggcgctata gaattggtaa ttatcgagtt atcgtacaaa
    29941 ttgtagatga tgaattagtt gttgctactc tagaagttgg tcatcggaga gatatttatt
    30001 aaattaaagc tgagtaataa cagtatagaa agtaaggaga gtaaaaattt gaagaaaaaa
    30061 tggttttttg cagattatta tgacacaaca attattttac ttgctttaat ctctgttatt
    30121 ctggtattac ttggatttgc tgagatgatt gatttggaca atccgcctta tagtattatt
    30181 gatttagtaa tctggggtgt ttttgtaatt gattatagtt ggcgcttttt tacgactaaa
    30241 agaaaatggc gctttattct tgaaaatatt tttgatttat tggctattct ccctttaaat
    30301 gctattttta cagtgtttcg attagggcgt atctttcgtt tagctaaact aacaaaatta
    30361 ctgaaactga ctcgtttact tagaataatt ggacttacag gtaaattaga aagaaaaatt
    30421 agtagattct tacggacaaa tggcctgatt tatatcttgt atgttaatat ctttattgtt
    30481 ctagtaggga gttcgatttt atccgttgtt gaagaaaaat ccttctcaga tagtctttgg
    30541 tgggctcttg tgacagtaac tactgttgga tatggggata ttgttcctgc ttccattttt
    30601 gggaaatggc tagcagtttt actgatgctt gtcggtattg gaacaatagg gatgttaaca
    30661 agtgctttga cgaacttttt tgtaaaggat aatccagatg aacagataaa acttgataaa
    30721 ctcaaagatg aattatcgag ccaaagaata ttactagaga aacaatctaa aaagatagaa
    30781 gaactacata aaatgataca agatttgatt gaaaaaacat aataaaaata aagatgagac
    30841 aaagtttgag ctgaggagaa atcaagtaag ttttgacaca atagaacgca tattatcagg
    30901 tataaaaact tgatactatg cgttttatag agaaataaaa taaaatctga acaaatcaat
    30961 taggaattta aagcatttta taacaacgtt ttagagtgat ggggtgctat ttcaacttca
    31021 acctactata atacagaaaa aaacaactcc ctgatgattc aaggagttgt ctatagttaa
    31081 attagttttt agaagcttct tggaattctg gatttttcca tgcttcgtca ataatagctt
    31141 gcaattcttt agcagatgct tgcatttttt gagtttctgc atcgttcaat ggaatgttta
    31201 ctggacgaac gataccatgt gcaccaacaa cagctggttg accgataaag acattctcaa
    31261 ctccgtatag accttcttgg aatactgaaa gtggaagtac tgcgttttca tcgtcaagga
    31321 ttgctttagt gatacgagca agggctactg cgataccgta gtatgttgca ccttttttgt
    31381 tgatgattgt gtaggctgca tcacgaacac cttcgaacaa ttcaatcaat tcagcttctt
    31441 gaacattttg agtgtcttta aggaattctt caaggtttac accagcgatg ttagcgtgtg
    31501 accaaacagc gaactcagag tcaccgtgtt cacccatgat gtaggcgtgc actgaacgag
    31561 catccacatc caatttttca gcaagtgctt gacggaaacg agctgagtca agtgaagtac
    31621 ctgaaccgat aacgcgttct ttagggaaac cagagaattt ccaagttgag taagtcaaaa
    31681 cgtcaactgg gttagcagca acaaggaaga tacctttgaa accagattca acaacttgag
    31741 ttacgattga tttgttgata gcaaggtttt tacctacaag gtcaagacga gtttcacctg
    31801 gtttttgagg tgcacctgca gtaatcacaa caaggtcagc gtctgcacag tcagagtatt
    31861 gagctgcata gattttttta ggtgaagtga aggcaagggc gtgactaagg tcaagcgcat
    31921 caccaacagc tttttcatgc aattgtggaa tttcgataat tccaagctct tgtgcaattc
    31981 cttggttaac aagtgcaaaa gcgtaagatg aacctacagc accatcaccg acaaggataa
    32041 cttttttgtg ttgtttagtt gaagtcattg ttttaaacat ctccttaatt ttattagggg
    32101 attttcccta gacaacttca ttctatcact tttaaaaaac tttgtcacga atatgcctta
    32161 tagttctcga tgtaaacgtt ttagtggttt agaggctgaa atagatggga atttatggta
    32221 taatgttgtt acttactaat tgtgaaatga ggcatttatt aatgcaggat aaaaatttag
    32281 tgaatgtcaa tctgacaaag gagatgaagg caagttttat cgactacgcc atgagtgtta
    32341 tcgtagcgcg agctcttcct gatgttcgag atggcttaaa acctgttcac cgtcgcattc
    32401 tctacggaat gaatgaattg ggtgtgaccc cagacaaacc ccataaaaaa tctgctcgta
    32461 ttacagggga tgtcatgggt aaatatcacc cacacgggga ttcctctatt tatgaagcca
    32521 tggtccgtat ggctcaatgg tggagctacc gttacatgct tgtagatggt catgggaatt
    32581 ttggttccat ggatggagat agtgctgccg ctcaacgtta taccgaggca cgtatgagca
    32641 agattgctct ggaaatgctt cgtgatatca acaaaaatac agttgatttc gttgataact
    32701 atgatgccaa tgaacgggaa cccttggtct tgccagcgcg ttttccaaac cttttggtta
    32761 atggagcaac tggtatcgcg gttgggatgg caaccaatat tccacctcat aatctgggtg
    32821 aaaccattga tgcagtgaag ttggtcatgg ataatcctga agtgactacc aaggacttga
    32881 tggaagtctt gcctggacca gattttccaa ctggtgctct tgtcatgggg aaatcaggta
    32941 tccataaggc ttatgaaaca ggtaaaggtt cgattgccct acgttctcgt acagagattg
    33001 aaacgactaa gactggtcgt gagcgcatcg ttgtaacaga atttccttac atggtcaata
    33061 aaaccaaggt gcatgagcat attgttcgct tggttcagga aaaacgcatt gagggtatca
    33121 cagcagtacg tgatgagtca aaccgtgaag gtgttcgatt tgttattgaa gtcaagcgcg
    33181 acgcctcagc caatgttatt ctcaataacc tcttcaaaat gacccaaatg caaaccaatt
    33241 ttggtttcaa tatgctcgct atccaaaatg gtataccgaa aattttgtct cttcgtcaga
    33301 ttttggatgc ttatatcgag caccaaaaag aagtggttgt tcgtcgtaca cgttttgata
    33361 aggaaaaagc ggaagcgcgc gctcatatct tagaaggtct cttgattgcg ctagaccata
    33421 tcgacgaagt gattcgtatc atccgtgcta gtgaaacgga tgcggaagct caagctgagt
    33481 tgatgagcaa gtttaagctt tctgaacgtc aaagtcaagc tatccttgat atgcgtcttc
    33541 gtcgtttgac aggtttggaa cgcgataaga ttcaatctga gtatgatgac ctcttggctc
    33601 tgattgcgga tttagcagat attcttgcta agcctgaacg tgtttctcaa attatcaaag
    33661 acgaattgga tgaagttaaa cgtaaatttt ctgataagcg ccgtacagag ttgatgattg
    33721 gacaggtctt gagtctcgag gatgaggact tgattgaaga atcggatgtc ttgattaccc
    33781 tttctaacag aggctacatt aagcgtttgg atcaggacga gttcactgct caaaaacgtg
    33841 ggggtcgtgg tgtccaagga acgggagtga aagatgatga ctttgttcgt gagttagtgt
    33901 caactagcac ccatgatcat ctgctcttct tcacaaacaa gggacgtgtc tatcgtctta
    33961 aaggttatga aattcctgag tatggtcgga ctgccaaagg gctaccagta gtcaatctct
    34021 tgaaattgga tgaagacgaa agtattcaga cggttatcaa tgttgagtct gatcgcagtg
    34081 atgatgctta tctcttcttt acaacccgtc acggtattgt gaagagaacc agtgttaagg
    34141 agtttgccaa tattcgtcaa aatggtctca aagcgctgaa tttaaaggat gaagatgagt
    34201 taatcaatgt cttgttggca gaaggagata tggatattat cattggtacc aagtttggtt
    34261 atgcagttcg ctttaatcaa tcagccgttc gtggtatgag tcgtatcgcc actggtgtga
    34321 aaggtgttaa ccttcgtgaa ggagacacag ttgttggtgc cagcttgatt actgatcaag
    34381 atgaggttct tattatcaca gaaaaaggat atggtaagcg tacagtcgct actgaatacc
    34441 caacaaaagg tcgtggtggt aagggaatgc agacagctaa aattaccgaa aaaaatggct
    34501 tgctggccgg tcttatgact gttcaagggg atgaggattt gatgattatc actgatacag
    34561 gtgtcatgat tcgaaccaat cttgccaata tttcacaaac aggacgtgca actatgggag
    34621 ttaaagtaat gcgcctggat caagatgctc agatagtgac tttcacaacg gttgcggtgg
    34681 cagaaaaaga agaagttggg acagaaaacg aaacagaagg tgaagaataa tgtctcaaaa
    34741 aaataataaa aagaaaaaca agcgaaaaaa tctgctgaca aatatcctag caggatttct
    34801 gatattactg tcactggctt tgatttttaa tactcaaatt cgaaatattt tcatagtctg
    34861 gaataccaat aagtatcaag ttagccaggt atcaaaagaa aaattagaag aaaatcagga
    34921 tacagaaggc aattttgact ttgattctgt caaagctatc tcttcggaag ctgttctaac
    34981 ttctcaatgg gatgctcaaa aattaccagt tattggggga attgcaattc ctgaattgga
    35041 aatgaatttg ccgattttta aaggacttga taatgttaat ctcttctacg gagctggtac
    35101 aatgaaacgc gagcaagtaa tgggagaagg aaattatagt ctagctagtc accatatctt
    35161 tggtgttgat aatgctaata aaatgttatt ttctccttta gataatgcta aaaatggcat
    35221 gaagatttat ctaaccgata aaaataaagt ttatacttat gaaatacgtg aagtcaaacg
    35281 tgtgacaccg gatcgtgttg atgaagttga tgatagagat ggggtcaatg aaatcacatt
    35341 agtaacctgt gaagaccttg ctgctacaga acgtattatt gtcaaaggtg atttgaaaga
    35401 aacaaaagat tattcacaaa catctgatga aattctaaca gctttcaatc aaccatataa
    35461 acaattttat taatacaaat cagtgaaatc atggatttca ctgatttttt aagattttca
    35521 taaaaatata gtaaaatgaa ataagaatag gacgaatcgt tcaggacagt caaatcgatt
    35581 tctaacaatg ttttagaagt agaggtgtac tattctagtt tcaatctact ataaactttt
    35641 atgaaataca gaaaacgctt cctaaaacct aaagtttgtg atataattat caagaaaaaa
    35701 gatttaggag tttattatgg tttcttcaga atttatctca aagattgaat ttgcttgcaa
    35761 taagaaagaa agtctttata gtcaaagcaa atttaagtat gcgattcgtt cgatgttcgc
    35821 aggtgcattt ttaaccttca gtactgctgc aggtgcagtt ggggctgact tgattaataa
    35881 aattgcacca ggtagtggac gcttcctctt tccattcgtt tttgcttggg gcttggccta
    35941 cattgttttt ttgaatgccg agttggtcac ttcaaacatg atgttcttga ctgctggtag
    36001 tttcttaaaa aaaatctctt ggagaaaaac agctgagatt ttactatact gtaccttgtt
    36061 caaccttatc ggagccttga tagcagggtg gggctttgct cattcggcag cctatgcgaa
    36121 tctgacacac gatagtttca tctcaggtgt tgttgagatg aagttaggcc gctcaaatga
    36181 attggtcttg cttgaggcga ttttggcaaa tattttcgta aatattgcga ttctgtcatt
    36241 tattttggtc aaagatggtg gtgccaaact ttggcttgtg ttgtcagcta tttacatgtt
    36301 tgtattctta acaaacgagc acattgcggc gaactttgct tctttcgcga ttgtgaaatt
    36361 cagtgttgct gcggattcaa ttgccaactt cggtgttgga aatatgcttc gccactgggg
    36421 tgtgactttc atcggaaact ttatcggagg aggcctcttg atgggtcttc catatgcctt
    36481 cctcaataaa aacgaagata cttatgtaga ttaagaaaat gagcacgatt gagtcgtgct
    36541 tttttcattt tcaaaataag gtaatagcta tttcttatat caaaatatag aaaactgata
    36601 tttgtaaact ataactcaag gtgctacaat atccttaata aaatgatatg gaggtcacct
    36661 tatgacttgt gattttaaat ttgaaactct acaactacat gctggtcaag ttgtggctcc
    36721 agctactaag tctcgtgcag tgccgattta tcaaacaaca tcttttattt ttgatgacac
    36781 gtaggaaggt gctgatctgt ttgccttgag gaaaccaggg aacatttata ctcgtatcac
    36841 caatcctaca acagctgccc ttgaaggtgg tgttgaagcg ctagcaacag catcaggtat
    36901 gactgcagtg acttatacga ttttggcgct tgcccatgct ggtgaccatg tagtggctgc
    36961 ttcgactatt tacggtggaa ccttcaatct tttgaaagaa ccccttcctc gttatggtat
    37021 cacaacaacc tttgtcgatg ttgataattt ggaggaagta gaagcagcta tcaaagacaa
    37081 taccaagctt gtcttgattg aaaccttggg taactccttg attaatattc cagacctgga
    37141 aaaactggca gagattgctc ataaacatca aatcccactt gtgtcagaca atacttttgc
    37201 aataccttat ttgattaacg tcttctctca tggcgttgac attgccattc actctgcgac
    37261 taagtttatc ggtgggcatg gtacaactat tggaggaata attgtcgata gtggtcgttt
    37321 tgactggacg gcttcaggga aattccctca atttgttgac gagggtccaa gctgccacaa
    37381 tttgagttat acttgtgatg tgggtgcagc agcctttatt atagctgttc gagttcaatt
    37441 gcttcgtgat acaggtgcag ccttgtcacc attcaatgct ttcctcttgc tacaaagact
    37501 tgaaacctct tcacttcgtg tggaacgcca tgtacaaaat gctgagacaa ttgttgattt
    37561 tcttgtcaac catcctaagg tagaaaaggt aaattatcca aaacttgcag atagtcctta
    37621 tcatgccttg gctgagaaat acttgccaaa agatgtcggt tcaatcttta ccttccatgt
    37681 caaaggtggc gaggaagaag cacgcaaggt cattgataat ttagaaatct tttctgacct
    37741 tgcaaacgcg gcagatgcta aatcgcttgt tgtccatcca gcaacaacca ctcacggtca
    37801 attgtcagaa aaagacctag aagcagcagg tgtcacacca aactaaattc gtttgtcaat
    37861 cggtcttgaa aatgtagaag atttgattga agacttgcgc ttggccttgg aaaaaattta
    37921 aagtaaaaga agataaacag tgggcttcga ctcactgttt ttgattttcc ctcaggcatg
    37981 atataatggt taaagaagtc tagaaagagg aacgatatga acgaaatcaa atgtcccaac
    38041 tgtggggaag tctttacagt aaatgagagt cagtatgccg aactcttgtc ccaagtgaga
    38101 acggcagagt ttgataagga actacacgat aggatgaagc aggaactggc cttggctgag
    38161 caaaaggcca tgaatgagca acagactaaa ctggctcaga aggatcaaga aattgcgcaa
    38221 ttacagagtc agatccaaaa ctttgataca gaaaaagaat tggccaagaa agaggttgaa
    38281 cagacaagcc atgaggctct cttggctaag gacaaggaag tacagctctt agaaaatcag
    38341 ttggctacct tgcgtttgga gcatgaaaat caactgcaaa agaccctttc tgacctagaa
    38401 aaagaacggg atcaggttaa aaaccaacta cttttgcagg aaaaggaaaa tgaattatct
    38461 ttggcttctg ttaagcaaaa ctacgaagcc cagctcaagg cagctagtga acaagtcgag
    38521 ttttataagg attttaaggc tcaacaatct acaaaagcga ttggggaaag cctagaacag
    38581 tatgcagaga gtgagtttaa caaggttcgt agtttcgcct ttccaaatgc ttactttgag
    38641 aaggataaca aggtctcttc gcgtgggtct aaaggggact ttatcttccg tgagtgtgat
    38701 gaaaatggag ttgaaatcat ttctatcatg tttgagatga aaaacgaagc agacggaaca
    38761 gagaagaagc acaagaatgc agatttttac aaggaattgg acaaggaccg tcgggagaag
    38821 aactgtgagt atgccgtttt ggtgaccatg cttgaggccg ataatgacta ctttaacaca
    38881 gggattgttg acgtcagcca cgagtatgaa aaaatgtatg ttgttcgtcc tcaattcttt
    38941 atccagttga ttggtctctt acgtaatgcg gcgctaaatt ccctaaaata caagcaggag
    39001 ttggccttgg ttcgcgagca aaatattgac attacgcatt ttgaggaaga cttggatgcc
    39061 tttaagctag cttttgctaa gaactataat tcagcttcga ctaactttgg aaaagctatt
    39121 gatgaaatcg acaaggccat caaacgcatg gaagaggtta agaaattcct gactacatct
    39181 gaaaaccaac tccgtctagc taacaacaaa ttggaagatg tctctgttaa aaaattgacc
    39241 cggaaaaatc caacaatgaa agcgaagttc gaagcactga agggggagta gaaagcaaaa
    39301 atgaacggta ttatcaactt aaaaaaagaa gcaggaatga cctcgcatga tgcggttttt
    39361 aaactgcgta agattttggg aaccaagaaa attggtcatg gtggaacctt ggatccggat
    39421 gtggtgggtg ttttgccgat tgcggttggc aaggcgacac gcatggtcga gtttatgcag
    39481 gacgagggta agatctatga gggggaaatc attctgggct attccacgac gactgaggat
    39541 gctagtgggg aagtggtcgc agaaacccct gttttgtctc ccttggatga aaagcttgtt
    39601 gatgaagcga ttgctagctt gactgggcct attactcaga ttccccctat gtattcggca
    39661 gttaaggtta atggtcgcaa gctctatgag tatgcgcgtg ctggtcagga agtggagcgt
    39721 ccagaacgtc aggtgaccat ttatcaattt gagcgaacaa gtccgatttc ttatgatggc
    39781 caacttgccc gattcacttt tcgtgtaaaa tgcagtaaag ggacttacat ccgtactttg
    39841 tcagttgatt tgggtgaaaa gcttggttat gcggctcata tgtcccattt gactcgtact
    39901 agtgctgctg gcttacaatt agaagacgct cttaccttgg aggaaattgc tgaaaaagta
    39961 gaggctgggc aattagattt tctccatcct ttagagattg ggacaggtga ccttgtcaaa
    40021 gttttcctaa ctccagaaga ggctacagaa gttcgctttg gtcgttttat tgagctagac
    40081 caaacggaca aagaactggc tgcctttgaa gatgataaat tgttagccat tctagaaaaa
    40141 cggggcaatc tctataagcc aaggaaggtt tttagctaga tcgtttagga ataaaaatcg
    40201 ggtgatagat aacaattgct tgataaaccc ccatactaat agtagaatgg ttttgggaat
    40261 tataatattc caattgttgc gagttgtaga tactcaaata atctatatag aaatttagag
    40321 gtgtgaaatg aagcaactta aaattctttc agataaatat ttagagtcca tgacaggttc
    40381 tggtgggaac ttaggtctag gatttggtgt gataattcca tgatgtgaaa tgagtttcga
    40441 gaaagggtgg agcaacttct tcaacaaaaa gaaataaatg aaaatagtga gttgagtcac
    40501 ctgtttcgtc ttgctataca aaatttagac agaaatgaaa aataccaatc ggtcatggcc
    40561 aatttgagtc aagggttgtc actttacctc atgacgcatc attaccaggc acctaagtct
    40621 gtcattgatt ttggtttatg gattgccaaa gctcctagcc aggaaagagg gagactggct
    40681 ttcttgcaga tgcttgctca aaccctacag ggctttcgtt aaaactgtcg aacatcagag
    40741 ggaagactct ggtgtttttt gctgatgaga ctataaattt tgtaaaaaat gtgatagaat
    40801 agacgacgga taaaataacg gaggatagca tgcaaaatag accaatcatt attggagtga
    40861 caggtggttc tggtggtggt aaaaccagtg tttcaagagc cattttatcg cattttcctg
    40921 atgaaaagat ttccatgatt gagcatgatt catactacaa ggatcagtct catttgacct
    40981 ttgaagagcg tgtcaaaacc aactatgacc atccttttgc ctttgataca gacttgatga
    41041 tcgagcagat taaggaattg ttggcagggc gtccggtgga catcccgacc tacgactata
    41101 cagagcatac acggagtagc aagacctatc gtcaggagcc tcaagatgtc tttatcgttg
    41161 agggcatttt ggtcttggag gacaagcgtc tgcgcgattt gatggatatc aagatttttg
    41221 tggatacgga tgacgatgtg cgtattattc gtcgtatcaa gcgtgatatg gaggaacgtg
    41281 gccgtagcct tgatagcgtt attaaccagt acttaggtgt ggtcaaacca atgtaccacc
    41341 agtttatcga gtcaactaag cgttatgctg atatcgtcat tcctgaaggg gttagcaata
    41401 ccgtggctat cgacctgttg acgaccaaga ttgcaaagat tttggaagaa gctcgaaaca
    41461 gcaaataatc acatgtggag gccttgcctc ctttttctat ttttccctca taatggtaca
    41521 taaatggaga tttttaggca tatttttggt ataataatac ccataaaaga gcaagtaaat
    41581 gaatagtagg tggagatgga aaagtattta tcggtaacaa ctttgaccaa atatctgaaa
    41641 atgaaattcg ataaagaccc atacttggaa cgggtctatt taactggtca agtttccaac
    41701 tttcgtaaac gacctactca ccaatatttc tccctaaagg atgaccatgc agttattcaa
    41761 gcgaccatct ggtctgggat ttatcagaaa ttagggtttg acctggaaga aggaatgaag
    41821 atcaatgtga ttgggcgtgt acaggtctat gaaccaagtg gtagctactc catcatcatt
    41881 gaaaaagctg agcctgatgg ggttggggcg cttgcgattc agtttgaaca acttaagaaa
    41941 aaattgacag aagaaggcct gtttcaagaa cgcttcaagc aagctctacc ccaattttct
    42001 aagagaattg gggtagtaac cagccgtagt ggagccgtta ttcgagatat tatcacgacc
    42061 gtcagcaggc gattcccagg tgttgacatc cttctttatc ctaccaaggt tcaaggtgaa
    42121 ggggctgcgg aggaaattgc tagaaatatt gcgcgtgcta atcaacggga cgatttggat
    42181 ttgctcatta ttggtcgtgg aggtggttct attgaggatc tctgggcctt taacgaagaa
    42241 attgtggtac gagctatttt tgaatctcgt ttgccagtta tctctagtgt ggggcatgag
    42301 acggatgtga ccttggcaga ttttgtggca gatcgacgcg ctgcaacgcc aacagcggcg
    42361 gctgaactgg caacacctgt gaccaagttg gatgtattag ctcatttgca aaatcaggaa
    42421 aaacggatgg caacggcagt ccgaaatgtt ctatctaaga aacaagaggc tttgaaaaaa
    42481 tgcagtcagt ctgttatctt tagacaacct gagcgcttgt atgacggtta tttgcaacgc
    42541 ttggaccaac tgcaactgcg tttgaaacaa agtttgcgaa ctcggatttc tgataacaaa
    42601 caattagttc aagcaagaac tcatcaatta gtacaattat cacctgttac caaaatccaa
    42661 cgctatcaag accgtttagg acagttggac aagctcttag gtagccaaat ggcgttagtt
    42721 tatgacgcca aggttgctga ggccaagcga ctttcggaag ctttgctcat gttggatact
    42781 agccgaatcg tggcgcgtgg ttatgctatt gtcaaaaaag aagagtccgt tgtagattcg
    42841 gttgagagtt tgaagaaaaa agaccaagta acgcttttga tgcgagatgg tcaagtagaa
    42901 ttagaggtta aagatgtcaa aacaaaagaa atttgaggaa aatctagcag aactggaaac
    42961 cattgtccaa agtttggaaa atggtgaaat tgctctggaa gatgcgatta ctgcctttca
    43021 aaagggcatg gtcttgtcaa aagagctcca agctacgctg gacaaggctg aaaagacctt
    43081 ggtcaaggtc atgcaagaag acggaacaga aagtgatttt gaatgaaaaa gcaagaaaaa
    43141 ttagctcttg tcgagtcggc tttggaagat ttttatggag accagcagtt tgcctctagt
    43201 ttacgggagt ctgttctcta ttctattcat gctggtggca agcgtattcg gccttttctc
    43261 ttgttagaag ttctggaatc cttgcaggtt accatcaaac ctgctcacgc gcaggtagct
    43321 actgccttgg agatgattca tacagggagc ttgattcacg atgaccttcc tgctatggat
    43381 gatgacgatt atcgaagagg gcggttaacc aatcacaaga aattcggtga agctatggcc
    43441 attttggctg gagatgcctt attcttagac ccatatgcct tgattgcgca ggcagatttg
    43501 ccaagtcaga tcaaggtgga cttgattgcc aacttatccc ttgcttcagg tagtctgggt
    43561 atggtggcag ggcaagtttt ggatatggag ggcgaacacc agcacttgtc tctggaagaa
    43621 cttcagacta ttcatgccaa taagactggg aagttactag cctatccctt ccaagcggca
    43681 gctattatag ctgaattgtc acctgaaatg caggtgaagc tgaaaactgt gggtgaattg
    43741 attggacttg cttttcaagt cagagatgat gtactggatg tgacagctag ttttgaggaa
    43801 atcggcaaga cacctcaaaa ggatctgcag gcagaaaaat caacctatcc tgccttgttg
    43861 ggcttggaag agtccattgc cttttgtaac caaaccctgg atcaagctaa tgaaaaatta
    43921 gaagaaattg cccagcagct tccctttgaa acagaatcga ttgtaagtgt agtagaaagt
    43981 ttgagaatca atggctaagg aaagagtgga tgtactagct tataaacagg ggttgtttga
    44041 aacgagagag caggccaagc gaggtgtgat ggctggtcta gtcgtagcag tccttaatgg
    44101 agaacggttt gacaagccag gagagaaaat tccagatgac accgaattaa aactcaaggg
    44161 ggagaaactc aagtatgtca gccgtggtgg tttgaaactg gaaaaggcct tgcaggtctt
    44221 tgatttgtcg gtggatggcg cgactacgat tgatatcggg gcctctactg gaggttttac
    44281 cgatgtcatg ctacagaata gtgccaagtt ggtctttgca gtcgatgttg gtaccaatca
    44341 gttggcttgg aaattacgcc aagacccacg agttgtcagc atggagcagt tcaattttcg
    44401 ctatgctgaa aagactgatt tcgagcagga gccgagcttt gccagtattg atgtgagttt
    44461 catttccctt agtctgattt tgccagcctt gcacagtgtc ttggctgatc aaggtcaggt
    44521 ggtagcactt gtcaaacctc agtttgaggc aggacgtgag cagattggga aaaatggaat
    44581 tattcgagat gctaagattc atcagaatgt ccttgaatct gtaacagcta tggcagtaga
    44641 ggcaggtttt tcagtccttg gcttggactt ttctcccatc caaggtggac atggaaatat
    44701 tgaattttta gcgtatttga aaaaagaaaa gtcagcaagc aatcagattc ttgctgagat
    44761 taaagaagca gtagagaggg cgcatagtca atttaaaaat gaataaaaaa gaaagacttg
    44821 aaaaaattag aagattggtg acagattatc aaatcggcac gcaagaagaa attgtagaac
    44881 atttgaaaga agcaggtatc actgccactc aggcgacggt atcccgagat atcaaagagt
    44941 taggtattgt caaaattcct ttgagagaca acacctatgt ctacgaattg ccaaaatcaa
    45001 tcgtaaaaag tctgcaactg gctgaagaca atatcgaatc ggctgaattg atggataaga
    45061 tgatcaatct ccaagttatt ccaggaaata cggcttttgt aaaagctcag ttaatcgaga
    45121 cttttgcaga caagattttt agctgtttga ctgatgatag ctcgatttta gtcattgcca
    45181 gaagtggaag tctagcagag gaaatctttg aacaagtaaa aaattggtag gtctatatgt
    45241 tacttgaaat ttcgataaaa aactttgcca ttattgaggc tatttccctc aattttgaaa
    45301 aggggatgac tgtcctgact ggtgaaacgg gtgcagggaa gtcgattatc attgatgcca
    45361 tgaatatgat gttgggagct cgtgcgacga cagatgttat tcgtcatggt gcaccaaagg
    45421 cagagattga ggggcttttc tcagttgaga atagtcgtct tttacaggaa atttttgatg
    45481 agcaaggttt agaattaggt gatgaaatta tcatccgtcg ggaaatcttg caaaatggtc
    45541 gtagtatcag ccgtgtaaat ggtcagatgg ttaatctgtc tgttttgcga actattgggc
    45601 aacatcttgt agatattcat ggtcagcatg accatgagga gttaatgcgt ccccaactgc
    45661 atatccagat gttggatgaa tttggtgatg ccgctttttg ggacttgaaa gaaacctatc
    45721 aaacgagttt tgatgcctat cggaaaatgc gcaagcaggt tctggaagtc aagaaaaacc
    45781 aacaggaaca caaggcacgt atcgaaatgt tggaatttca aatggcagag attgaggcag
    45841 caaacttgca ggctggagaa gacttggatc tcaatcaaga gcgagataaa ctcctcaacc
    45901 acaaaaatat tgcggataca ctgaccaatg cctacagtat gttggacaat gaagattttt
    45961 caagtctggc caatgttcgt tcagccatga atgacatgga aagtgtcgaa gagtatgacc
    46021 ctgaataccg tgaaatttca agctctctgt ctgagaccta ctatgtttta gaagacatta
    46081 gcaaacgttt ggaagctatc attgaggacc ttgattttga tggcaatcgc ctcatgcagg
    46141 ttgagaatcg tttggacctc cttcatacta ttactcgtaa gtatggtggg actgttgatg
    46201 atgttttgct ttattttgcc aagattacgg aagaatacaa tctcttgaca ggcaataatc
    46261 tttcgtctga ggacatggaa gcagagctta agaagttgga agtcaatctt gtcaatttgg
    46321 caggtcaact tgcttctgct cgtcataatt tggctcagca actcgaagct gagattaaac
    46381 aagaactgca agatctttat atggaaaaag cccagtttca ggttcgtttt agtaagggaa
    46441 aattcagtcg tgagggaaat aaaatggttg agttttatat ttcaaccaac cctggagaag
    46501 actttaaacc cttggttaag gttgcttctg gaggggaatt atctcgtctc atgttagcca
    46561 ttaagtctgc cttttcacgt aaagaaggca agactagcat tgtctttgat gaggtggata
    46621 cgggagtttc aggtcgtgtt gctcaagcta ttgctcagaa aattcataaa attggtcagc
    46681 atggtcaggt tttggctatc tcccatttgc cacaagtaat tgcgattgca gattatcaat
    46741 tctttattga gaagattagt aatgaccatt caacggtttc gactgttcgt ctcttgacgg
    46801 tcgaagagcg agtggaggaa gttgccaaga tgttggcagg tgatgatgtg acagaagcag
    46861 ccctgacgca agcaagagaa ttgttgagaa acagggagaa ataagatgac agattattat
    46921 gtaattggag atgttcacgg aaaagctggg atgctggaag accttctcaa aacctgggat
    46981 ggtcagcccc agttgctctt tctaggtgat ttgattgaca gaggtgagga tagtcaccgt
    47041 gttcttgaaa tggtcaagga cttggtggac aatcaagggg ctatctgttt gtccggaaac
    47101 cacgagtata tgtttttgac ttggctagat gacccagaag aaagttatga ccattatagt
    47161 cgcaatggtg gagatacaac cattaactct atcctaggtc gtcccttgga tgcaccagtt
    47221 gatggagtag aagatgccaa gcgggttgcc gctgaagcgg cagacttggt cgaattcatt
    47281 cgtcaaatgc catttgtagt agagacagac aagtatatct ttgttcacgc aggtattgat
    47341 ttgaccttgg acgactggca tgaaacaaca gattataaaa aagtatggct tagaaaacca
    47401 ttccacggag ctgaaaatca tactggaaaa accattgtct tcggtcatac accggtctat
    47461 ggtttattac agcaagaacg cggtacatct gagctttgga ctacagaaga tggcaagatt
    47521 ggaatggatg gaggagctgt ttatggtggt gtccttcacg ggattgtctt tacagaccaa
    47581 ggaatgacag aacaccactt tatcgaaaat gacggctttg tcgctgaaga ttagtactcc
    47641 tagcagggta tggtcttgtc aaaatatcaa aaacaattta taataaatag ataccctgaa
    47701 aggaagagaa tcatgaactt agaagaattg aaaaaacgac aggagaagat ccgtaacttc
    47761 tctattatcg cccatattga ccacggaaaa tcaactctag cagaccgcat tttggaaaaa
    47821 acagagacgg tttcaagtcg tgaaatgcag gcccagcttt tggatagcat ggagctagag
    47881 cgggaacgtg gaattactat taagttgaat gccatcgagt tgaattacac tgcaaaagat
    47941 ggggaaactt atattttcca cttgattgac acaccagggc acgttgactt tacctatgaa
    48001 gtttcacgtt cgctagctgc ctgtgagggt gctattttgg tggtcgatgc ggctcaagga
    48061 attgaggctc aaactcttgc caacgtttat ctggctttgg ataatgattt ggaaatcatg
    48121 cctatcatta ataaaattga cctgccggct gcagatccgg agcgcgtgcg tacagagatt
    48181 gaagatgtga ttggtttgga tgccagtgaa gcagttttgg cttctgccaa ggctggtatt
    48241 gggattgaag aaatcctcga gcaaattgta gaaaaagtac cagcaccaac gggtgatgtg
    48301 acggcgccac ttaaggcctt gattttcgac tctgtttacg atgcttaccg tggggttatc
    48361 ctccaagtgc gtgtcatgga cggagtggtc aaacctggtg ataagattca gctcatgagc
    48421 aatagtaaga cctttgatgt ggccgaagtc ggtattttta caccaaaagc ggttggtcgt
    48481 gatttccttg cgactggtga tgttggttac attgcggcgt ctatcaagac ggttcaggat
    48541 actcgtgtgg gtgataccgt taccttggca accaatcctg cggcagaacc attacatggt
    48601 tataagcaga tgaatcctat ggtctttgcg ggtctctacc caatcgaatc aaacaagtac
    48661 aatgacctgc gtgaagcgct tgaaaaattg caactgaatg atgctagtct tcagtttgaa
    48721 ccagaaacat ctcaggcact tggatttggt ttccgttgtg gatttcttgg acttctccat
    48781 atggatgtta tccaggaacg tttagagcgt gagttcaata ttgacctcat catgacagct
    48841 ccgtctgtta tttacaaagt taatttgacc gacggtgagt ctatggatgt gtctaaccca
    48901 tctgagtttc cagacccaac taagattgcg accattgaag agccttatgt caaggcgcaa
    48961 atcatggtac cacaggagtt cgtcggagca gtaatggagc tagctcagcg taagcgtggg
    49021 gactttgtga ctatggacta tattgatgat aaccgtgtca atgttatcta tcaaattcct
    49081 cttgctgaaa ttgtctttga cttctttgat aaacttaagt cttcgacacg tggttatgca
    49141 agctttgact acgaattgtc agaatatcgc ccatctaagc tggtgaaaat ggatattctt
    49201 ctcaatggag ataaggtgga tgccctcagc tttatcgttc acaaggactt tgcctacgaa
    49261 cgtgggaaac tcatcgttga taaactcaag aaaatcatcc ctcgccaaca atttgaagtt
    49321 ccaatccaag cggctattgg acacaagatt gtcgctcgta ctgatatcaa ggcccttcgt
    49381 aagaacgtac ttgctaaatg ttatggtggt gacgtttctc gtaagcgtaa actccttgaa
    49441 aaacaaaaag ctggtaagaa acgcatgaaa tccatcggat cagttgaagt tccgcaagaa
    49501 gccttcctca gcgtcttgag tatggatgaa gaataagtta tcagaaatgc ctttccttgt
    49561 tcacaggaaa tttataagaa tcaatagtaa agcaggctta gatggtctgc ttttttagtt
    49621 tttatactct tcgaaaatct cttcaaacca cgtcagcgtc gccttaccgt atgtatggtt
    49681 actgacttcg tcagtttcat ctacaacctc aaaaccatgt tttgagctga cttcgtcagt
    49741 ttcatctaca acctcaaaac tgtgttttga acaacctgcg gctagcttcc tagtttgctc
    49801 tttgattttc attgagtatt agaacagaaa aaatgcttgg agtatttgtt tgtgtgttta
    49861 cttttatata acaaactata aacacaacaa aaatataaaa aaagagacaa aaaagaacag
    49921 aaagtaatta acaacgattt catatagtgt tatacttata gcataaagtt aatggaaaga
    49981 agggaaaacc ttatggtatt agattatttc tttgacaaaa accttgtgtt ttgcttagaa
    50041 gcggataatc aagaataact ctttgatcag gtagcaagct tgttggagga acgagaaatt
    50101 gtaactccaa cttatcgtga agccttgatc acgcgtgaaa agtcatttcc a
//
LOCUS       DAVBCA010000007        48474 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.007, whole genome shotgun sequence.
ACCESSION   DAVBCA010000007 DAVBCA010000000
VERSION     DAVBCA010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48474)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48474)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48474
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.007"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(308..1474)
                     /gene="recA"
                     /locus_tag="VQU19_000366"
     CDS             complement(308..1474)
                     /gene="recA"
                     /locus_tag="VQU19_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HET2479678.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVPLDLGDELEIEIEE"
     gene            complement(1529..2785)
                     /locus_tag="VQU19_000367"
     CDS             complement(1529..2785)
                     /locus_tag="VQU19_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HET2479679.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNLLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQVDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGISSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            complement(2869..3885)
                     /locus_tag="VQU19_000368"
     CDS             complement(2869..3885)
                     /locus_tag="VQU19_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HET2479680.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNVERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEKALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSVGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            complement(3893..4411)
                     /locus_tag="VQU19_000369"
     CDS             complement(3893..4411)
                     /locus_tag="VQU19_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2479681.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            complement(4401..4844)
                     /gene="tsaE"
                     /locus_tag="VQU19_000370"
     CDS             complement(4401..4844)
                     /gene="tsaE"
                     /locus_tag="VQU19_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HET2479682.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            complement(4930..5550)
                     /locus_tag="VQU19_000371"
     CDS             complement(4930..5550)
                     /locus_tag="VQU19_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2479683.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            complement(5933..6796)
                     /locus_tag="VQU19_000372"
                     /pseudo
     CDS             complement(5933..6796)
                     /locus_tag="VQU19_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            7470..7766
                     /locus_tag="VQU19_000373"
     CDS             7470..7766
                     /locus_tag="VQU19_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000911560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HET2479684.1"
                     /translation="MLKFRKVVASSLAVLAFSLALPVLAVSHRGGEWTYGGHHDPNNW
                     GAFSNYYHGSQYHWAYVGSNGRNNQKTVYAGARSAAYAFVNTNFGEQVTFDAGW"
     gene            7869..9884
                     /locus_tag="VQU19_000374"
     CDS             7869..9884
                     /locus_tag="VQU19_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HET2479685.1"
                     /translation="MKKLFILISNLLASLFFVWVFTIWTDTYVSYYYPNVVVHDSSPE
                     TTFQHVATRLEKLAEETDSFIAIQHQDPNSEGTTVFSYTTFGDGKLPDGLQEKKLEDA
                     QSSSVETNYFVFDGHLDIHLLREELSQLGLTNMNLTIPSKLSTLMAIFSNGFQLISLL
                     IFILTFIALTLISQISQLRSSGIRLISGEKRWSIFLRPVGEDLKGIAVGFSLAGVLAI
                     LMQKILSLPTQSLMTIGAGLLSYNLILLSISLFFAQLFAVGIKKIHLMQIIKGQVPVR
                     GIISLILIGQLLAIIIVTLGIGSSLKYSQAWQQHRIGQEAWSQERQLITLSISREGTS
                     PGFDEQAQRKLRTWYQLMDLAVSEQKAFLSRHQLIDRTLQNGMASSKNLITSTEWHDY
                     NPNGNVLIVTPQYLERQNIPVDTTIEQKMNHLDVGEFVLLLPEHLRSEEEHYKSVFED
                     DLTSRMSSQDERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQ
                     SILFWIDAVQNYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVM
                     LAGAGLGIATSILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLG
                     FVASVFLQVEIGVAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            9886..10518
                     /locus_tag="VQU19_000375"
     CDS             9886..10518
                     /locus_tag="VQU19_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2479686.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLTYLDLDKRIFELSGGESQRVALAKVILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDRLK"
     gene            10659..10937
                     /locus_tag="VQU19_000376"
     CDS             10659..10937
                     /locus_tag="VQU19_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComA"
                     /protein_id="HET2479687.1"
                     /translation="MKKFDNYIVEKPCDSNSDKLQKILIIENLVDDILQFPLRINNSV
                     GEIFLLQPFQKKTIFIPCYFEEDIVKVKDDDKVEWNLLEFQKFRAFLA"
     gene            complement(11446..11859)
                     /gene="ndk"
                     /locus_tag="VQU19_000377"
     CDS             complement(11446..11859)
                     /gene="ndk"
                     /locus_tag="VQU19_000377"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HET2479688.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEVIQNVVHGSDSEESAKREIALWF"
     gene            complement(11970..15647)
                     /gene="rpoC"
                     /locus_tag="VQU19_000378"
     CDS             complement(11970..15647)
                     /gene="rpoC"
                     /locus_tag="VQU19_000378"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HET2479689.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGEVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPYAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(15680..19291)
                     /gene="rpoB"
                     /locus_tag="VQU19_000379"
     CDS             complement(15680..19291)
                     /gene="rpoB"
                     /locus_tag="VQU19_000379"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HET2479690.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVVAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSSLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            19707..19777
                     /locus_tag="VQU19_000380"
     tRNA            19707..19777
                     /locus_tag="VQU19_000380"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19739..19741,aa:Cys,seq:gca)
     gene            complement(19975..21306)
                     /locus_tag="VQU19_000381"
     CDS             complement(19975..21306)
                     /locus_tag="VQU19_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HET2479691.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPVIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFNVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(21597..22421)
                     /gene="endA"
                     /locus_tag="VQU19_000382"
     CDS             complement(21597..22421)
                     /gene="endA"
                     /locus_tag="VQU19_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HET2479692.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSTANSPKTKLSQKKQ
                     APEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(22460..22648)
                     /locus_tag="VQU19_000383"
     CDS             complement(22460..22648)
                     /locus_tag="VQU19_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HET2479693.1"
                     /translation="MNKKSSYVVKRLLLVIIVLILGTLALGIGLMVGYGILGKGQDSW
                     AILSPAKWQELIHKFTGN"
     gene            complement(22641..23924)
                     /gene="murA"
                     /locus_tag="VQU19_000384"
     CDS             complement(22641..23924)
                     /gene="murA"
                     /locus_tag="VQU19_000384"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HET2479694.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(23948..24178)
                     /locus_tag="VQU19_000385"
     CDS             complement(23948..24178)
                     /locus_tag="VQU19_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HET2479695.1"
                     /translation="MVQLLFTLSSHMLFIYVSFYLLKDLVRWEKVLKVTAENTRKVRV
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(24236..25273)
                     /locus_tag="VQU19_000386"
     CDS             complement(24236..25273)
                     /locus_tag="VQU19_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HET2479696.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(25257..25745)
                     /gene="coaD"
                     /locus_tag="VQU19_000387"
     CDS             complement(25257..25745)
                     /gene="coaD"
                     /locus_tag="VQU19_000387"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HET2479697.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLCVGIFFNPHKQ
                     GFLPLENRKRGLEKALGHLENVEVVASHDELVVDVAKRLGATCLVRGLRNASDLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEK
                     KD"
     gene            complement(25735..26274)
                     /gene="rsmD"
                     /locus_tag="VQU19_000388"
     CDS             complement(25735..26274)
                     /gene="rsmD"
                     /locus_tag="VQU19_000388"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HET2479698.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEVGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAERELFSEDVMVVCETDKTVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(26339..27331)
                     /locus_tag="VQU19_000389"
     CDS             complement(26339..27331)
                     /locus_tag="VQU19_000389"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HET2479699.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(27443..28126)
                     /locus_tag="VQU19_000390"
     CDS             complement(27443..28126)
                     /locus_tag="VQU19_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HET2479700.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYLLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(28182..28922)
                     /locus_tag="VQU19_000391"
     CDS             complement(28182..28922)
                     /locus_tag="VQU19_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HET2479701.1"
                     /translation="MTIITSKANSVVKNAKKLHQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRNQLAAFPQTVWISEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            28956..29234
                     /locus_tag="VQU19_000392"
     CDS             28956..29234
                     /locus_tag="VQU19_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HET2479702.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            29312..30238
                     /gene="yidC"
                     /locus_tag="VQU19_000393"
     CDS             29312..30238
                     /gene="yidC"
                     /locus_tag="VQU19_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HET2479703.1"
                     /translation="MKSIKRFAFSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(30313..31107)
                     /gene="pflA"
                     /locus_tag="VQU19_000394"
     CDS             complement(30313..31107)
                     /gene="pflA"
                     /locus_tag="VQU19_000394"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HET2479704.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTSQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(31233..32483)
                     /locus_tag="VQU19_000395"
     CDS             complement(31233..32483)
                     /locus_tag="VQU19_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HET2479705.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     ISLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(32550..33377)
                     /gene="purR"
                     /locus_tag="VQU19_000396"
     CDS             complement(32550..33377)
                     /gene="purR"
                     /locus_tag="VQU19_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HET2479706.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLHEFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(33644..34585)
                     /locus_tag="VQU19_000397"
     CDS             complement(33644..34585)
                     /locus_tag="VQU19_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HET2479707.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMTNKIFAMDNRSFYKPDLD"
     gene            complement(34575..35831)
                     /locus_tag="VQU19_000398"
     CDS             complement(34575..35831)
                     /locus_tag="VQU19_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HET2479708.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVVVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFARDIRNKYI
                     APPRTTNFGILFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(35833..36495)
                     /locus_tag="VQU19_000399"
     CDS             complement(35833..36495)
                     /locus_tag="VQU19_000399"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HET2479709.1"
                     /translation="MSEYKLSENNWTRVAVFAGGDRGHYRTDFDGFVGVDRGSLWILE
                     EDLPLALAVGDFDSVTEEERQVIQKRAQYFVQARPEKDDTDLELALLTIFKQNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLASYMHQIEIEDGQNLITYCPEGISQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(36458..37114)
                     /locus_tag="VQU19_000400"
     CDS             complement(36458..37114)
                     /locus_tag="VQU19_000400"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HET2479710.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDGHFVP
                     QISFGAGVVEALRPHSKMVFDCHLMVSNPEHHLEDFVRAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTPVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALRDEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGDVNERVQTLRKQLD
                     "
     gene            complement(37125..38003)
                     /gene="rsgA"
                     /locus_tag="VQU19_000401"
     CDS             complement(37125..38003)
                     /gene="rsgA"
                     /locus_tag="VQU19_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HET2479711.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDGGELDFYQQTYGDIGYDFVTSKEELLPLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     TAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGTIAPFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(38596..39369)
                     /locus_tag="VQU19_000402"
     CDS             complement(38596..39369)
                     /locus_tag="VQU19_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HET2479712.1"
                     /translation="MRKKLVNSLMCAVVLSGFPIATYANEKNIGPNITVSNGQTRLSI
                     PEKNGVEVIQSEENRVVYEVKEAAKIETSDGDMVAPIVVDSRITSINNQVVQGKTVYT
                     ADLEKATFVEEGYNKLAKPTNILDHIFGIQKVHAYTQNITTHQSQFDSTYSVELYTVV
                     HWVSYDGGVQKNITKISGGVDFHERDIEIESSSVEVRQGGWYSSQQKWFHPGARSSWE
                     YSTGFSKVGPGENRVVTNYTVNLIRYGDRWSAYLQNNPW"
     gene            complement(40059..40931)
                     /gene="rsmA"
                     /locus_tag="VQU19_000403"
     CDS             complement(40059..40931)
                     /gene="rsmA"
                     /locus_tag="VQU19_000403"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HET2479713.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAEVMAFEIDHRLVPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPDLPIKVVANLPYYITTPILMHLIESGIPFSEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPVPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLE
                     EFASLADALKGQGL"
     gene            complement(41182..41400)
                     /locus_tag="VQU19_000404"
     CDS             complement(41182..41400)
                     /locus_tag="VQU19_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2479714.1"
                     /translation="MENMTNPLLLVQIRVHGYLLDFASSEGQRQKHYRLKNLPQTVEL
                     TVDDVEEDVDLTLPENRSYQEADFFDTQ"
     gene            complement(41468..42109)
                     /locus_tag="VQU19_000405"
     CDS             complement(41468..42109)
                     /locus_tag="VQU19_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2479715.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(42111..44141)
                     /locus_tag="VQU19_000406"
     CDS             complement(42111..44141)
                     /locus_tag="VQU19_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HET2479716.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEVLSHLAVEHNSLIARRIVEPNEAGETLFTYATYGEGELPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLAATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQFICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     SGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSTYYQRLFTDYL
                     QNFSSESVEVTSQKYYLPQVSLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(44410..45309)
                     /locus_tag="VQU19_000407"
     CDS             complement(44410..45309)
                     /locus_tag="VQU19_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2479717.1"
                     /translation="MLIGQKIKEIRIEKGVSRPYFCGDEQELTVRQLSRIESGASQPS
                     LPKLAYIARRLGVPVYSLMPDFSALPPAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMSQIIEKEVYSTNDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTKLENFFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALREERDFSLAESFYQSSKTFAK
                     LIGDGFLVKKLTEEWQEDVKKYL"
     gene            complement(45381..45941)
                     /gene="rnmV"
                     /locus_tag="VQU19_000408"
     CDS             complement(45381..45941)
                     /gene="rnmV"
                     /locus_tag="VQU19_000408"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HET2479718.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINAQDIERI
                     QRLHQRQGVIVFTDPDFNGERIRRMIMTAIPTVRHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(45941..46714)
                     /locus_tag="VQU19_000409"
     CDS             complement(45941..46714)
                     /locus_tag="VQU19_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HET2479719.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVTQMNIVGFDKPTIE
                     RALELVDEYDQLYATIGWHPTEAGTYTEEVEAYLLDKLKHPKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKVTDLQEAAKELPLDKILVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            complement(47019..47912)
                     /locus_tag="VQU19_000410"
     CDS             complement(47019..47912)
                     /locus_tag="VQU19_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HET2479720.1"
                     /translation="MVAQDPKAQDSTKPTAEKSTVKAPAQRVDVKDITHLTDEEKVKV
                     AILQANGSALDGATINVAGDGTATITFPDGSVVTILGKDTVQQSAKGESVTQEATPEY
                     KLENTPGGDKGGNTGSSDANANAGGGSQAGGSAHTGSQNSAQSQASKQLATEKESAKN
                     AIEKAAKDKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGV
                     QAIVMVTVPKRPVAPNAAPKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAALAS
                     LGLVVATSGFALLGRKTRRRK"
     gene            complement(48196..48330)
                     /gene="rpmH"
                     /locus_tag="VQU19_000411"
     CDS             complement(48196..48330)
                     /gene="rpmH"
                     /locus_tag="VQU19_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HET2479721.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
BASE COUNT        13990 a        10915 c         9042 g        14527 t
ORIGIN      
        1 taaagctatt atatcagctt tccagaggag cgacaagaaa cagcaaactt atatatagcg
       61 gaatgaaata aggaaagtca aatcgatttt taacaatgtt ttagaagtag atatgtacta
      121 ttctagtttc gatctattat agttggttga gtttggaata gtacgctgta gctgctaaaa
      181 catttctaga aattaatttg actttcctaa tagagttgtt catatcttat ttcaagctac
      241 tatatataat ctaaaaactt gaatcaaaaa tcgaaaaagt agcggatttc tccactgctt
      301 taacagctta ttcttcaatt tcgatttcaa gttcatcgcc taagtcaagc ggaacttctt
      361 cattcactgc ttcttctttc tttggctcat cttttttgtt ttcagtatct tgttctgaaa
      421 cttcttctcc atcaatcaag ccaaatttag aacggacttg cttatcaatt tcatcaaaga
      481 tttctgggtg ctctgccaag tatttcttag cattctcaga accttgccca attttttcat
      541 ctttgtaaga ataccaagcc cctgcttttt tgataatatc caaatcgctt gcaatcttca
      601 aaagctcacc agtcttagaa attccttctc cgtacataat ttcaactacg gcttccttaa
      661 acggtggagc taccttattt tttacaacct taatcttagt ttctttaccg acattggttt
      721 ctttttggtc accagttccc ttaatttgtg tattaccacg aacatccaag cggactgaag
      781 catagaattt caaagcacgt ccgcccggtg ttgtttctgg atttccaaac atcactccaa
      841 ctttttcacg caattggttg ataaaaatgg caattgtttt ggttttattg atagaggcgc
      901 caagtttacg catggcctgg ctcatcatac gagcctgcaa accaacatgg ctatctccga
      961 tatctccatc aatttccgca cgaggaacaa gggcagcaac tgagtcgact acgacaagat
     1021 caactgcacc tgagtcaatc aattttcccg caatctcaag accttgctct cctgagtctg
     1081 gttgagacaa gagcaattcg tcaatattga caccaagggc cgcagcataa gctggatcaa
     1141 gggcatgttc cgcatcgata aaagcagcaa tcccaccttc tttttgcgct tgtgcaactg
     1201 catgaagggc aaccgttgtc ttaccagatg actctgggcc atagatttcg atgatacgtc
     1261 ccttaggata accacctgag ccaagggcaa tgtcaagagc taaagaacct gagctcatca
     1321 cttgcacctt ttgctccgca cgttcaccca aacgcatgat tgatccttta ccaaagtctt
     1381 tctcaatcaa tttaagagcg tcattcaagg ccttttcacg ttctgcccca aatttttttg
     1441 aaatttcttc taattttttt ggttttttcg ccattctatt ctcctacatt ctaatgatcc
     1501 tcagacctat ctactattat atcaaaaatt agtcacttaa taaagccttg cgaactaggt
     1561 taaaggcatg cataaccgca atgtgacgta catctgctcg gcttctgcct ccaatattaa
     1621 ccttgataac ctcagttcct tgatcttgcg ccaagcctat gaagactgtc ccaactgggt
     1681 gtccttctag gctatctggt cctgccactc cagtcaaact aattccaaaa tcagactggg
     1741 tcttgcttcg tgcctgctca gccatcttct gagctgtaaa ttcagacacc acaccatgtt
     1801 cttccaaatt cttggcagga atatccaaca tccttgattt ttcctccaag ctataggtca
     1861 caaaaccacc cttaaatata cttgaaattc cagaaaaatt cgccacggta gcttggaaaa
     1921 gacctgccgt caaactctct gcagccgcga tggttttccc ttgccttttc agttcttcta
     1981 ccacaatgct ggctaaacta gtttcttccc cataaccata gcaaaagtct cgtaaagaaa
     2041 ttccttcgaa agtctggcag tccaagattt gattttccaa gatatccagc gcttgattcg
     2101 cctcttcttg actgctagcc tttgttgaca gacgtagagt gacttctcct gtcttggcat
     2161 aaggggccaa ggtaggatcg acctgattat caattaaatc agccaaaatc gtaaccagct
     2221 ggctctcgcc aatcccaaag aaacgaagaa ctcgggaata cagcttgctc cctgtcatca
     2281 acttgggtag aagtaggttt aagaccatgg gtttcaattc acttggcgga cctggaagga
     2341 cgacataggt cactccgtct acttctaatt ttcctccaac agccagtcct gtttcgtttg
     2401 gcagtggaat cgctccttct acaatttgag cttgtctttc gttattcggt gttcgggcat
     2461 agtctggtcg cagggcaaaa aagatatcca acttctcctg agcctgagga tcaaagacta
     2521 atgctttccc taaaaattta gctagggttt gtttggttag gtcgtcctca gttggcccca
     2581 aaccgcctgt caaaatcacc agactgctac gttgactggc aatctcaagc aaagacaaga
     2641 gacgaacttc attgtctcct acagccgtct gaaaatatac atctacccca atctcagcta
     2701 gtttttccga caaaaactgg gcattggtgt tgacaatctg tcctgtcaaa atctctgttc
     2761 caacagcaat gatttctgct ttcatgtttc ctcctaccta tctattcgta tttttttgaa
     2821 aaaatcgcag gaattttcct acgattgatt ttttatttgt atcaaaagtt aattatcttc
     2881 atcaccaaca ggtgctctgc caaataaatc ttcaaataaa accgcattgg tttcaagctg
     2941 agtaacttct tcttgtccca aagaacgtcg gagtatattt tgcatttcca acatatgtgc
     3001 tcttgaaaca atctggtaag aaacaccttg aagtatctct ccttcaccct gcaactgctg
     3061 agtttcaatg gttttaaatg aatctttata gcctagcaag ttagggatac tttttgcaga
     3121 caaatcaata ttggtctgca tattgtcact caaagctttt agaatctctt gataatgacc
     3181 aacgctattt aaactgagag ctttttccat gactttttga ataacttcac gttgacgttt
     3241 ttgacgacca taatccccct caggatcttg gtaacgcatt cgtgcataga ctagggcttt
     3301 ttctccccca atatgttgct ccccaacacc gatagaaata gtattaaatt cttcttggtc
     3361 actgatagaa attgggaaac ctaggatatt attgactgta atacctccta ctgcatccac
     3421 tagtttttgc aaccctctca tattgaccat cacatagcga tcaatatgga tattcatcat
     3481 tttttgaatg gtttctatag caagctctgc tccaccatct gcatatgctg agttcagttt
     3541 cgcttcatga gcctgaccat tccctgattc aatgcgcgtc agaatatccc gctctaaact
     3601 catcattgtt gtttttttcg ttttaggatt cactgtcatc aagatcatgc tatcacttct
     3661 accgacccaa gtttcagttc gttcaacatt tccggtgtcc actcccatta acagaatggt
     3721 tagaggttca gtcgcttcaa taaccttggt ttcttcgccg atttttttat aggttttagc
     3781 taaggtttct gtcccttgtt gataaatagt ataagcaaaa acacctactc ctactacagt
     3841 tacagaaagt aaagctagca ccattccaat aattttttta accatatttc tactaaccta
     3901 tcagtttacc catcaagtaa acatcgataa atttcccttc ttctatatat gccccacgct
     3961 cttggctacc ttcaatgaca aagccatgct tttgataaag atggactgct gcttgattac
     4021 gagtttggac agtcagttgg agacgacgca gaatgccact tgcttgtgcc cactctatcg
     4081 cttcttctag caacaaactt cccaagccat tattccaata tctttttcca atcacaatga
     4141 agagatctcc aatatgacgg actctcttac gctgatcagc tgtaatattt acaataccag
     4201 caattttgcc atttaagaat gcaagtaagg ttatctgatt gtccgaacta gcttgcttgt
     4261 tgaggaatat ttccatctcc tcactagtca agagaatacc atctccgtct aggctggtaa
     4321 agtctgtctc caaactcaca cgatttaaaa aggccactaa ttcagctgca tctttgggct
     4381 ctgcttccct aatgagcaat tcatactcca tattgaagct cctctaacaa tttctcagca
     4441 cgcaaaccct ttgcctgaaa atttaaacgg cgtccatctg cttcttttag aatttccaat
     4501 tctaaataag catctggcaa ggcatctcct aagagatttc cccactcaat aacagtcacg
     4561 ccgccaccaa agataaactc atccaagtcg atagaatcag catctccttc aatacgataa
     4621 acatctaggt gataaagtgg aagtcgacct tcatactctc tcacgatagt ataggtggga
     4681 cttttaatca tttgagaaat ctgtaatcct tttgcaagtc ctttagtaaa ggtcgtttta
     4741 cctgcaccca gttctccagt taagattaaa acatcattct ttgctaatag atggcccaaa
     4801 cgctccccta aggcttgcaa ctcttcttca ttttttgtgt acatactctt attataccaa
     4861 aaacttttct tttgtgtcta ttttcctact aaacttatca tcataacatc cataaaaaac
     4921 aggctttctc taaaagaaaa tgagcgtaac aatgaccaat acaagatctc ggaaaatatg
     4981 accataaaag gaaacttcct tcttaaccga atttgggaca agataggctg caaaaaacaa
     5041 gcccagtcca atataaatca gaagtgagac aatggtcatt ggatttctta agaaaagaag
     5101 tgttgctaaa atagtcacca acactgtctt ttttctgtct agcatagcaa gaaaatcgcg
     5161 cacgtatttt ttcaagggta aaaaaatcag caaatctagc ccaaatagga aaaagaagga
     5221 tggcaataaa aagtcaacta attcttgctg cagcgtattt ttgatgaaca agttatctga
     5281 caaaacaaga acagctccta acaaattaat taagagtaac atactgtaaa aaagcttcac
     5341 cgacttctta ctggctagga cactatggac ttcttgctta cgggtataaa gataatttac
     5401 tccagcacag attcctgaaa cgaaaaccat gctcccgatg aaaaaagctg tactttgttt
     5461 aaaggacaag atgcattcct tccataggaa acagctactc aaactgattt gaattaaagc
     5521 taacaaaaat aagattctca ttgatttcat cttctctctc ccttcctacc aatcattata
     5581 ctaggagaaa agagagaact gtttctaatc ttctcaaatg tctctttaag acgctaaaca
     5641 aacactagag actaatactc aatgaaaatc aaagagcaaa ctaggtagct agccacaggt
     5701 tgctcaaaac actgttttga gattgcagat agagctgacg tgatttgaag agattttcga
     5761 agaatataaa tttgaaatca tgaaaatccg tcaaacgggt ggttgttttg tctcgcacct
     5821 cacggagcga gacggactca gagtcacata attataaggc tgatagtatt aatctaacta
     5881 tcagccttac aggttattta acgtttcaga aaaactataa tgtcaagatt aactaaacag
     5941 tatctaattc cttcaaataa ttttctatct tcatcagcat taaaggattg ttataaatct
     6001 tgcatagctc tcttgcttct atataataat ttttgacttg ttctctgtct agaaatttgg
     6061 ctccagcatt tcctacaaga ataagtagag gagccaattg gtagcttgtc tgtctttgtt
     6121 tacagagttc gatagtctca agagcttctt ggatggcttc attatatttt tcctttgata
     6181 ctaggtagtg agcgtaattg taacgaactc tgatgtagcc aaataaaaac tcttgatgct
     6241 caaaattttt tgtctgatat aactccatca aatgagagta gtttacctca tattcttgtt
     6301 cacgacccac taaggaatag aaattagata gagtattcaa cgcctttaaa taaatcaaag
     6361 tatttgagga gacttttaat aatatatttt ccaatgaaga aattgcttca cacttactgt
     6421 catattgaca gaagtcaata atagctttaa tccattcaag gtaagttcgg tcttctagtg
     6481 ttagaaaagt acttcgttca atctctattc tataaatata ttccaaattt tcataatttc
     6541 tatcatctaa taggcgagca gataattgct tgaaattaga gaggttagat ttaatttcaa
     6601 tttgttcatt aaaaaaataa tctaatggca cttcgagtcg ttgtgagagt ttgaacaaaa
     6661 ggtctgcgga gggaatgaaa taccctctct caattttact aatctggctc tattcacaaa
     6721 ttccttctgc aagagtttgt tgggagagtc tcaactcttt tcttttcaat ctgaatttct
     6781 ctgcgagtgt attcattaaa gataataaac cttcctattt gcttaatttc attataaaat
     6841 ttttagttca aaatagcaag ttaaaggaat aaataattct ttgcggtaat aaacaaaaaa
     6901 aagtcaaaaa ttacataaaa atgcttggct aaataaaata tatttgttaa aataaggata
     6961 atgaaaaaga aaagggtttc acgaatgaag aaaaatcgtg gaattcaaaa attagctata
     7021 ttagtattac taggtgtttt tatgtttagt aacacaattc cttaccaaca gtttattcag
     7081 aagaatagac aattggagat tcgagtccaa tcgcaaaaga agtccaatgg tcttgatgtt
     7141 gggaaggctg attgatttta tattacttta aaattcaact atttagagaa aggtattctg
     7201 atgagagctt gtaacaatac cagatagata taagaatgga gatgtttgat aaaatgcttt
     7261 catagctaac caactgttga aaattatgag ttacaaaatc taaagtattt aagattggtt
     7321 tataaaatta ggtctctgcc tgtagaaagg aacgtgcagt tagaaaggag gaaaaaatag
     7381 gatactataa ttcagactga gatttctaat taaaatatat agttgcattt cgctcatttt
     7441 cataatattt cattcagagg agtaataata tgttaaaatt tagaaaagta gttgcatcat
     7501 cccttgccgt tttggcattt agtttggctc ttcctgtttt ggcagtttct caccgtggtg
     7561 gcgagtggac ctatggaggc catcatgatc caaataattg gggagcattt tcgaattatt
     7621 atcatggttc acagtatcac tgggcctatg ttggaagtaa tggacgtaac aatcaaaaaa
     7681 cagtttatgc aggagcacgt agtgcggcct atgcgtttgt taatacaaat tttggggagc
     7741 aagttacatt tgatgcggga tggtaaagaa taattgaaga agattctttt atcaatagtt
     7801 cagtaagctt gttagtttat agagggcagg ggtatttctg ccctctgttt tagaataagg
     7861 aatgcactat gaaaaaatta tttatactca tatccaacct gcttgctagt ttgttctttg
     7921 tttgggtatt taccatttgg actgatacat atgtctccta ttattacccc aacgttgttg
     7981 tacatgattc ttcccctgaa acaacttttc agcatgttgc tacacgcttg gaaaaactag
     8041 cagaagaaac agatagcttt attgcgattc aacaccaaga tcctaactca gaaggtacta
     8101 cagttttttc ttatacgacc tttggggacg gaaagttgcc tgatgggctt caggaaaaaa
     8161 aactagaaga tgctcaaagt agtagtgttg aaacaaacta ttttgtattc gatggacacc
     8221 tagatattca cttgctaagg gaggagctaa gtcaacttgg cttgactaac atgaacctga
     8281 caattccatc taaactatct acgttaatgg ctatctttag taacggattt cagttaatca
     8341 gtctattgat tttcatctta acctttatag cactgacttt aattagtcaa attagccaat
     8401 tacggtcgtc gggcattcgc ctcatttcag gagagaaacg gtggtccatt ttccttagac
     8461 cagttggtga ggatttgaaa gggatagctg ttggtttcag tttagctggc gtgctcgcca
     8521 ttcttatgca aaaaattctg tcgcttccaa cgcaatccct aatgaccata ggagcaggct
     8581 tgctcagtta taatctcatc ttgttgtcga tctccctgtt tttcgctcaa ctcttcgcag
     8641 ttgggataaa aaagatacac ctgatgcaga ttataaaagg gcaagtgcct gtcagaggaa
     8701 tcattagttt gattttaatc ggtcaactat tagcgattat tattgtaacg ctgggaatag
     8761 ggagtagctt aaagtattcc caagcctggc aacagcatcg gattggacaa gaggcttgga
     8821 gtcaggaaag gcaactgatt accctatcaa tcagccgtga aggaacgagt cctggttttg
     8881 atgaacaagc tcaaaggaaa ctcagaactt ggtatcaatt gatggatctg gctgtttcag
     8941 aacaaaaggc tttcttatct agacaccagt taattgaccg tactttgcaa aatggcatgg
     9001 cttcctccaa aaacttgata acctctacag aatggcacga ttacaacccg aatggcaatg
     9061 tccttatcgt cacaccgcaa tacttggagc gtcaaaacat tcctgtagat acaactattg
     9121 agcaaaagat gaatcacctt gatgtagggg agtttgtctt attgctgcct gaacacctcc
     9181 gttcagagga agaacattat aaatctgttt ttgaagacga cttaaccagt cgcatgtcta
     9241 gtcaagatga acgacagcaa atgactgcta cggtaggtta tttagaatca ggtcaggatc
     9301 gttttgtgta taatacgacc cctatttctt accagcagtt tttgaaagat ccaatcatca
     9361 ttgttataac accccaatca actggtccac agtccatttt gttttggata gacgcagtac
     9421 agaactacgt tctctttaat caattgtctg atgcccagga gcttatccag agacaaggca
     9481 ttgaaaattg ggtctcagaa atgcaaacag gttaccacaa ctacatcaca ttattggata
     9541 atattcagag ggaacgttgg gtaatgctag caggagctgg gcttgggatt gcaacttcaa
     9601 tcttgttgtt taacactatg aataggctct actttgaaga atttagacgt gccattttta
     9661 tcaaacgcat tgcaggtctc aggttcttag aaatccatcg cacttatctc tttgctcaac
     9721 tgggtgtgtt tttactggga tttgttgcga gtgtatttct tcaggtagag ataggagttg
     9781 ctttcttagt cttgttactc tttactggtc tatctctttt acagttacat gtccaaatgc
     9841 agaaagaaaa caagatgtcc atgcttgttt tgaagggagg ttaatatgat tgaacttaaa
     9901 caggtgagta aatcttttgg agaacgagag ttattttcga atctttcaat gacatttgag
     9961 gctggaaaag tctatgcctt aattggttca agtggtagcg gaaaaacaac cttgatgaac
    10021 atgattggga aattagaacc ttatgatggg acgatttttt accgaggtaa agacttggcc
    10081 aattataaat cgagtgattt tttccgtcac gaattgggct acctcttcca gaactttggc
    10141 ttaattgaaa accaaagtat tgaagaaaac cttaagctag gtctcattgg tcaaaagttg
    10201 agtcggtcgg aacagcggtt gaggcagaag caggctttag aacaggtcgg cctgacttat
    10261 cttgacctag ataagcgcat ctttgagtta tcgggcggag aatcgcaacg ggttgccttg
    10321 gcaaaagtta tcttaaagaa tccacccttt attctggcag atgagccaac agcttcaata
    10381 gacccagcaa cttctcagtt gattatggag attctgctat ctcttcgaga tgataatagg
    10441 ctaatcatta tcgcaacaca taatccagca atttgggaga tggctgatga agtgttcacg
    10501 atggatcgtc tgaaataaaa atccttgttt ttaattgcac gatgagttac tgaaatatta
    10561 tcatgaatca ataattggag ttaatttaga attgtacttt attaatattg aggtaacttt
    10621 ttcttgataa aggaagaaat agtggagagg aagttagaat gaaaaaattc gacaattata
    10681 ttgttgagaa gccttgcgat tctaattcag ataaactgca aaaaatctta ataattgaaa
    10741 atttggtaga tgatattttg caatttcctc tcagaatcaa taatagtgta ggagagattt
    10801 tcctcctaca accgtttcaa aagaaaacta tctttattcc atgttatttt gaggaagata
    10861 ttgtgaaagt caaagatgat gataaagttg agtggaattt gttagaattt caaaaattta
    10921 gagcattttt ggcttagtaa tctgtgttga aggctcaaaa cctatggtaa aaaagtcgct
    10981 ttgaaaacgt attgcctcca aagatttagt taaataatga tttaacacaa aaagaaatta
    11041 ttgaagttct ggaaagatgt tgtttcagta ttgagaaaag gtgggaaaaa cttgcgattt
    11101 tcacagagaa aggaagaaaa agtatagaaa tatagtcaat tgaaacaaga acaggacaaa
    11161 agaacctttt gtgccatatt tttctccttt cgctttacaa ttggcttgaa cacctttatt
    11221 gtatcgcgtt tggagttttt ttggtataac cttcgacgcg cacccgcata gcgggtgttt
    11281 ttttgtctcg cacctaacgg agcgagacga actaatagtc acttaatcaa aaaacgcacc
    11341 atatcaaaaa ctaaaaagtt tgatatcatg cgtcatgtct taaactaatt gactatactt
    11401 tctattcaaa tgagctttta accaattgat tgagccaatc cactcttaaa accaaagagc
    11461 aatttctcgc ttagctgact cttctgaatc tgaaccatgt acaacatttt ggataacctc
    11521 attttctcca gcagcttttg caaaatcacc tcgaatagtg cctggtaaag cttcttctgg
    11581 acgagttgca cccatcatgg tccgccaagt ttcgattact ttgggaccag aaatgacacc
    11641 cacaagaact ggacctgaag tcatgaattc acgaatcggt gggtaaaaac tctgaccaac
    11701 caagtcctga tagtgctggt caatcaactc ttctgaaact tgtgaacgaa actccaattt
    11761 ttcgattgta aatccacgtt gttcgatgcg ctttaacact tcacccacta gccctctttt
    11821 tacaccatct ggtttgatga taaagaatgt ttgttccata cccgtctcct ttgtcagctt
    11881 ctttctttta ttttaccaca tttcgtggaa aaatggagaa agttttcaga atagagaatg
    11941 agagaacccg agggttctct cattctctat tattctactg tttcttccac agtttcaacg
    12001 gcagtatcca caactacttc tgttgtttct tcatttcctt cttcctctac tggaggatta
    12061 aggtattctt cttcgttgac agcatatggt tcaaggttac ggtaacgggc cataccagta
    12121 ccagctggga tgatcttacc gatgataaca ttttctttaa gtccaaggag atggtctttc
    12181 ttaccacgga tagctgcgtc agtaaggaca cgagttgttt cctggaagga agccgctgac
    12241 aagaaactgt ttgtttcaag tgaggctttg gtaattccca taaggactgg gcgacctgtc
    12301 gctggaactc cacctgcgat aaggacatct ttgttggcat ctgtaaagtc attgatatcc
    12361 atgagggtac ccatgagaag atctgtatca cctggatcca tgacacggac tttacggatc
    12421 atttgacgaa ccattacctc gatgtgtttg tcaccgattt ctaccccttg gctacggtaa
    12481 actttttgta cttcaccgag aaggtacgtt tcaactgaca agacatcacg aactgcaagg
    12541 agacgttttg gttggataga accttctgtc agagcagcac cacgcgctac ttggccccca
    12601 acttcgacac gcatacgagc tgtaaatgga acgacatatt caccttcgcc agtttcaccc
    12661 ttaacaaaga ctttcttggt acgagttgat gcatcttctt cgatagcagt aacttctcct
    12721 ttaacctctg tgataaccgc ttccccttta ggattgcggg cttcaaagat ttcttggaca
    12781 cgaggaagac cctgagtgat atcggtattt gaggcaaccc cacctgtgtg gaaggtacgc
    12841 attgtaagct gtgtaccagg ttccccgata gattgggcag caatggtacc aactgcttca
    12901 ccaacttcaa ccgcatcacc agtcgccaag ttgataccgt aacagtgacg gcagacaccg
    12961 tgacgagtgt tacatgtaaa tacagaacgg atagtcactt cttccacacc agcattgaca
    13021 atttcacgcg ccttgtcttc tgtaatcaat tcatttggac caataatcac tgcaccagtt
    13081 tctggatgtt taacagtttt cttagtgtaa cgaccgttga gacgctcttc gagagactcg
    13141 atcatctctt ttccttctgc gatagaacgg atcaagagac cacggtcagt tccacagtcg
    13201 tcctcacgga tgataacgtc ttgggcaacg tcgaccaaac gacgagtcaa gtaacctgag
    13261 tcggctgtct taagggccgt atcggtcata cctttacgag caccgtgagt tgagaagaac
    13321 atttccaata ccgacaaacc ttcgcggaag tttgaaagga ttggcaattc catgatacgt
    13381 ccattcggag cagccatcag accacgcata ccggcaagct gtgagaagtt tgagatgtta
    13441 ccacgggctc cagagtccat catcataacg attgggttct taggatcttg gttagcaatc
    13501 aagcgtttct caagtttttc acgggcagca cgccattcag ctgtaacagc attgtaacgc
    13561 tcgtcgtctg tgatcatacc acgacggaat tgtttggtga tttgctcgac acgtttgtgt
    13621 gattcttcaa tgatttcagc cttgtcatca acgactggga tatcggcaat acccactgtc
    13681 aatcctgcaa gagttgagtg gtggtaaccg agattcttca tgcggtcaag tagggcagaa
    13741 gtttctgtcg tacggaaacg tttgaagatt tcagcgatga tatttccgag gtttttcttc
    13801 ttgaacggag ggttgagctc aagattgctg atagcttcct tgatatctcc accaagtggc
    13861 aagaagtatt tagctggaac accttctgtc aagttggcat tgtttggttc ttgcaagtat
    13921 ggtagcccct ctggcatgat atcgttgaag agaattttac caactgttgt aagcaagacc
    13981 ttatgtcttt gctcttctgt ccaaggcttg ttgaggctgt ctgttgcgat accaacacgt
    14041 gagtggaggt gaacataacc attgcggtaa gccataaccg cttcgtcacg gtctttgaag
    14101 accattcctt caccttcgcg accagcttct tccatggtca agtagtagtt acccaaaacc
    14161 atgtcctgag atggagtaac taccggtttc ccatctttcg gattcaagat gtgctcagca
    14221 gctagcatga ggatacgagc ttctgcttgt gcttcttctg aaagtggtac gtggatggcc
    14281 atttggtccc cgtcaaagtc agcattgtag gcttcacaga caagtgggtg caagcgaaga
    14341 gccttaccat caatcaagac tggctcgaag gcttggatac ccaaacggtg aagggtcggt
    14401 gcgcggttca aaagcactgg gtgttcttta atcacttctt caaggatatc ccagatacgc
    14461 tcatctccgc gttccaccaa gcgtttagct gctttgacgt tttgcacgat atcacgggca
    14521 acgatttcac gcatgacaaa tggtttaaag agttcaatcg ccatttcacg tggcacacca
    14581 cattggtaca tcttaagagt tggaccaacg gcgataacgg aacgtcctga gaagtcaaca
    14641 cgtttaccga gcaagttttg acggaagcgt ccttgtttac ctttaagcat gtggctcaat
    14701 gatttcaatg gacggctacc tggtcctgtg attggacgac cacgacgacc attgtcaatc
    14761 aaagcgtcaa ctgcttcttg aagcatacgc ttctcatttt gaacgatgat acctggtgca
    14821 tttaactcaa gcaaacgagc caaacggttg ttacggttga taacacggcg gtaaaggtca
    14881 ttcaagtcag atgaggcaaa acggccacca tccaactgca acattggacg aagatctggt
    14941 gggataaccg gaagaatgtt aagaatcatc cattcaggtt tgtttccaga cttgtaaaag
    15001 gcatccaaaa catccaaacg acggatggct ttgacacgtt tttgtccagt agctgttttc
    15061 aattcttctt tgagttcagc aatttctttt tcaagatcta cttgcttcaa aaggtcttgg
    15121 atggcttccg cacccatctt ggcaacaaat gaaccataac catattcacg caagcgctct
    15181 cggtattcgc gctctgtcat gatagacttg tgctcaagtg gtgtatcctt aggatcaatc
    15241 accacataag ccgcaaagta gataacttcc tcgagggcac gagggctcat atcaagggtc
    15301 aagcccatac ggcttggaat ccccttgaag taccagatgt gagatacagg agctttcaat
    15361 tcgatatgtc ccatacgctc acgacgaact ttcgtacgcg ttacttcaac cccacagcgg
    15421 tcacaaacaa ttcctctgta acgaatgcgt ttgtacttac cacaagcaca ttcccagtct
    15481 tttgtaggac caaagatcac ttcatcaaag agtccttcac gttctggttt caaggtacga
    15541 taattgattg tttcaggttt tttgacttct ccataagacc atgaacggac tttacttgga
    15601 gaagctaggg tgatttgcat acttttaaaa cgatttacat caaccactat ttcttccctt
    15661 tctattctaa gtgaactgct tattcttgtt cagcagcttc ttctgttgct tccgcttttg
    15721 ttgctttctc agcttcttca gcttcaaagg ctgctttagc ctcttgagct gctttttcgc
    15781 gggctttttc aaggtcatct acgtggatga catcttcgtc cattccttca tccaagtcgc
    15841 gaagttccac ttcttggtca tcttcgtcta ggacacgcat gtcaagacca agagattgca
    15901 attctttgac aagaactcgg aaggattctg gaacacctgg ttttggaatt ggtttgcctt
    15961 ttgtaatagc ttcataggct ttcaaacgtc cgttgatatc gtccgacttg taagtcaaga
    16021 tttcttgaag gacatttgac gcaccgtagg cttcaagagc ccaaacctcc atctcaccga
    16081 aacgttgtcc accaaactga gctttacctc cgagtggttg ttgggtaaca gttgagtaag
    16141 gtccgactga acgcgcatgc aatttatcgt caaccatgtg gtggagtttg atcatgtaca
    16201 tgactccaac agaaacacgg ttatcaaatg gttcacctgt acgtccatcg taaaggattg
    16261 tcttggcatc gctatccata cctgcttctt taacagttga ccaaagatct tcagaacttg
    16321 ctccatcaaa gactggtgtc gcaatgtgaa taccaagagt acgagctgcc ataccaaggt
    16381 gaagctccat aacctgaccg atattcatac gtgatggcac cccaagtggg ttcaacatga
    16441 tgtcgactgg agttccgtct ggaaggtaag gcatgtcttc tacaggaacg atacgagaga
    16501 caaccccttt gtttccgtga cgtccggcca ttttatctcc gaccttaatc ttacgttttt
    16561 gagcgatgta aacacgaacc aacatgttaa cacctgattg caactcatct ccatttacac
    16621 gtgtaaagat cttaacatca cgaacgacac catcggcacc gtgtggtaca cgaagagaag
    16681 tatcacgcac ttcacgagac ttgtctccaa agatagcgtg caagagacgt tcttcagctg
    16741 aaagatcttt ctcaccctta ggtgttactt tacctacaag aatatcacct tctttaacct
    16801 cagcaccaat acggataatc cccatttcgt caaggtcttt gagggcatct tcaccaacgt
    16861 ttggaatttc gcgagtgatt tcttcaggcc caagctttgt atcgcgcgtt tctgattcgt
    16921 attcttcaag gtgaacagat gtgtagacat cgtccttcac caagcgttcg ctcatgataa
    16981 cggcatcctc gaagttgtaa ccttcccaag tcatgtaggc aacgattggg ttttgtccaa
    17041 gcgccatttc tccattttcc atagaaggtc cgtcagcgat gaaatcgcct ttttcaacga
    17101 catcaccaac ttttacgaga gtgcgttggt tgtaagcagt acctgagttt gaacgacgga
    17161 atttttggat gtggtaaaca tccaatgaac catcttcacg acgaacttct accttgtcag
    17221 catctgcgta agtaacttta ccatcatact gagcaatcac agccgcacca gaatcgtggg
    17281 ctgcttggta ttccatacca gtaccaacgt aaggtgcctg aggattaatc aatggcacag
    17341 cctgacgttg catattggct cccatgaggg cacggttgga gtcatcgttt tccaagaaag
    17401 gaatacatgc tgtcgcaacg gcaactacct gttttggtga aacgtccatg tagtcaacaa
    17461 tattagctgg atactcttgg ttgacccctt ggtgacgtcc catgacaatc ttctcagcaa
    17521 aggttccatc ttcattcaga ctagagttag cctgagctac agtatattca tcttcttcat
    17581 cagctgtcaa ccaaacaatt tcgttcgtga caacacctgt ttcacggtca accttacggt
    17641 atggtgtttg aacaaaacca tatttgttca agtgtccgta agatgacaag ttattgatca
    17701 aaccgatgtt aggtccttca ggtgtctcga ttggacacat acgaccatag tgagtgtagt
    17761 gcacgtcacg tacttcatat ccagcacggt cacgagtcaa accaccaggt cctaaggctg
    17821 acaaacggcg tttgtgagac aactcagaaa gcgggttgtg ttggtccatg aactgtgaca
    17881 actgtgatga accaaagaat tctttaactg cagctgttac aggacggata ttgataattt
    17941 gttgtggtgt caagacttca ttgtcctgaa cagacatacg ttcacggaca ttacgttcca
    18001 tacgagaaag tcccaaacgt acttggttgg caagcaattc accaaccgca cggatacgac
    18061 gatttccaag gtggtcgata tcatctacac ggccaagtcc ttcagccaag ttgaggaagt
    18121 agctcatctc agcaaggata tctgcaggag tcaccgtacg aaccttgtca tctgggttag
    18181 cattaccaat gatcgttacg acgcgatctg gatcagttgg agcaacaacc ttgaattttt
    18241 gaagaacaac aggctcagtc acaacggctg catcgtttgg gatgtagaca atcttgttca
    18301 agtcgccatc caaatggctt tcaatgcttt caatcacgct acgagtcata atcgtaccag
    18361 cttctaccaa gatttctcca gtttcagggt ctaccaatgg ctctgcaatg gtttggttga
    18421 gcaaacgtgt tttaacattg agttttttat tgattttgta acgaccaact gctgccaagt
    18481 catagcgacg tgggtcaaag aagcgagcca caagcaagct acgtgagctt tcagctgtct
    18541 taggctcacc tggacgaagg cgttcgtaaa tttctttcaa ggcttcgtct gtacgagagt
    18601 ccattggatt cttgtggata tctttttcaa cagtgttgcg aaccaattcg ctgtcaccaa
    18661 agatatcaaa gatttcatca tcacctgaga aaccaagagc acgaaccaag gttgtaaatg
    18721 gaatcttacg agtacggtcg atacgagtgt aggtgatatc ttttgagtcg ctttcaagtt
    18781 ccaaccaagc tccacggtta gggataacag ttgaaccata gcccacctta ccatttttgt
    18841 ctactttgtc gttaaagtaa acacctggtg agcggaccaa ctgagaaacg ataatacgtt
    18901 caccaccatt gatgatgaaa gtacccattt ctgtcatgat tgggaaatca ccaaagaaaa
    18961 cttcttgggt cttgatttcg cctgtttctt tattgatcaa gcggaaggtt acaaaaattg
    19021 gtgctgagta gctagcatcg tggatacgag cttcttctag cgtgtatttt ggttccttga
    19081 tttcatatcc aacaaattcc aactccattg tgtctgtgaa gtttgaaatt ggcaatacat
    19141 cttcaaacac ttccttaaga ccgtggtcta ggaaagcttt gaatgagtca gtttgaattt
    19201 caatcaaatt tggtaagtca agaacttctt tgattcttga aaaactacga cgggtacgat
    19261 gtttcccgta ttgaacgtca tgtcctgcca agatgattct cctttgtaaa taagttccaa
    19321 gccttgtcaa tcaggctttt ctaatcgcca tatggttgta aaccccttat caccgtgtcc
    19381 tcttgacgaa ttttcagaat ctttaagcct ctgttacaaa tgctcaaaat cttgaaaaaa
    19441 agcacaaaaa gagcagctaa atctgacttt ttcagaagat ttaactgctg tgagccttgt
    19501 ctggacaata tttcagacaa aacctacgac aaatgattac ccatattata ccctatttag
    19561 ctagattttt caaggggatt cagtaggttt ttggtaattt ttttcccata gaaaacttgg
    19621 catcacattc gaatcacgct atggtacaaa aaactgaaaa aactattgac tgaaaatcat
    19681 tttcaaggta taataataaa cgttaaggcg gtatagccaa gtggtaaggc acggctctgc
    19741 aaaagcttga tcgtcggttc aaatccgtct accgccttct ataacttgat ttatcaggtt
    19801 tcaaatgaac agaaagccca atttgaaggg ctttttttat tttccctcga ataaatacgt
    19861 ataactttaa aaacttttgg agcgagtttg tggcagagtt ctttccatgg cataattccc
    19921 ttttgaaatc aattgaaaaa agcttcgtca cgcctggtga caaaagcctc tagtttattc
    19981 tgtttcttct tctatttcga cttctgtgat ttggactttt accttggtaa cacgtccatt
    20041 cttcacttta tcattggtta agataaactg tttgttttgg ctgaccaatt catagctgag
    20101 tttctcagtc gttggaatgg ttcccactcc tgtcaaataa taaccagcga tagtatcaac
    20161 gtcatcactt tccagttcaa cattaaagta attattgaaa tcattgaggg tcatagttcc
    20221 ttgaacaatg taggtatcct cgccaatctg atgaacatct attgctgctt tgtccgtttc
    20281 atcatcaatt tcaccaacaa tttcctctaa gaggtcttcc aaagtcacca aaccagccat
    20341 accaccgtat tcatccagca agattgccat ttgtctttgg gtatttcgca gttcttttag
    20401 caagtcatcc acaaaaatag tttcaggtac aaaaagtgga tcttgtaaaa ttctcttcca
    20461 aacaatattg tcaaaaccgt ccacaaagcc tgccttaagg agactcttgg tgtgaatgat
    20521 tccaattaca ttgtccttat ccccatcata aaccgggata cgagaataat tttgttttaa
    20581 aatactttgg ataatggctt gactatcatc ctgaatatcc accataaagg catccgttcg
    20641 aggaaccata acctctcgtg ccatcagttc atcgagcgaa aagacacctt gtaacatctc
    20701 aatctcatca gcatccaatg tttcttcact atttgtcagc atataggcaa tttcatcacg
    20761 ggtcatcttt tcatccgcat catcgaatga cataggagtc aaatggctca agaaattggt
    20821 cgaagcagct aaaagccaaa caaaaggact gactagtttt ccgatcccaa tgataaccgg
    20881 cgctgtacga attgccaagg catcctttag attaagagcg attctcttag gatataattc
    20941 cccaaaaacg atggaaatat aggtcaaaaa tgccaaggat agaaaagttg ccacggcttg
    21001 tgctgtttcg ccattcccaa gccaagaggc aatcacacgt cctagagtat cagttaaact
    21061 cgcccctgat aagattgtaa tcagggtgat tcctacctga atggttgata aaaagtggtt
    21121 aggattttct agtaccttca gcaggcggat gtagcgtctg tctccttctt ccgccttttg
    21181 ttcaactcgg gcacgattaa gagaaaccat ggccatttct gtggctgaga aaaaggcatt
    21241 taataccgtc aagataaaca ataaaacaaa ttgtagcaac aaattctgac tacttgggtc
    21301 ttccatagtt cttctcctaa aatagtatct tatcctttat tatatcacaa aatttaatcc
    21361 aatacatatt atttttttct tagcgtaact tccatctctc tcccaaaact ggaagttagt
    21421 ctaagacgga tttccactga tttcacgcgt ttttctcata ctaaaagcta ggttgtggga
    21481 aactggaagt tagttttaga agttactatt ttttcttagt acctgttcta gccctgctta
    21541 aactagtaaa aagaactcct acatccataa gtgacatagg agtttaggct tatcttttac
    21601 tgagttacag ttacttctcc agttcggtaa tccagttgaa gtcccttttg aacattggga
    21661 actagaacat tgaattccaa ttctccatcc gaagacttgg cttcaatctg tgaagctgag
    21721 ggaactaaat cctcgtttga agcgtagtaa agggttacac ggtaacggac acgcttgttt
    21781 tggtccaagg ctttacgcac cttgctttca tagtagtttt gaccagtcga atactcggct
    21841 tgtgcctgat ttgcccaggc tgtctgaaca gcaatgtttt taggattgct tgttgaggca
    21901 tcaaaaccat ccaaaccacc gattaaggca tagcctaaca aatgacctct atcgactgca
    21961 tgggtataag agccctttag attcttgacc tgatgccaac ctggaggagt ccaagaagtt
    22021 gaaccattcc cagtttcttt acgattcttg tactgacgag tggccttaga caagagggca
    22081 ttagctacgg ttggaacagt ttccttaccc actgtctttg ttttattgtc agcgtagggc
    22141 ttacttgaaa ccttggcatc tagatttgtt ttattaccat tgacgataaa agcacctgag
    22201 ccattccact ccagactccc ctttatttga ctcttgactg cgtctgttaa gacactctct
    22261 gccaatgctt gactaggagc ttcaggcgct tgttttttct gactaagctt ggttttagga
    22321 ctattagctg tcgactgcat ctgcttgata taatagctcc ctgtagacaa aagcaataac
    22381 actagcagtc cgattagtgt ctgtcttgtt tttttgttca tatttctcct tatctttaga
    22441 aaaaggctgg ttctccagcc taatttcctg taaatttatg aatcaattcc tgccattttg
    22501 ctggagacag gatagcccat gaatcttgac ccttgcccaa gattccataa cctaccatta
    22561 aaccgattcc tagagccaga gtacctaaaa tcagtactat gatgactaaa agtaaacgct
    22621 tgactacgta gcttgatttc ttattcatct tcatcacttg cctcaatccg ctgaatctta
    22681 gcacctagct gcgccaactt ctcatggaaa ccgtagtaac ctctatccaa gtgaaccaat
    22741 ttaccgacca cagtttctcc ctgtgctacc aaacctgtca aaatcaaagc tgcactggca
    22801 cgaaggtcag ttgaaagaac ttctgctccc tgcaaaggct gtccaccaac aatacgagct
    22861 gtatcacgga taatctcaga atgcaagccc atgcggcgca tctcttctag gtgttggaaa
    22921 cgattttcaa aaactgtctc caccatggtt gattcgcctt ttgcaactgt catcaaggct
    22981 gtaaattgag cctgcatatc tgttggaaat cctgggtggg gcaaggtttt cacatgaaca
    23041 gcttttagat tttccagttg agaacgaaca cgaattcctt cgtcttcttc aattacttca
    23101 acacccattt caagtaactt ggcaatcaag ggacggttgt gctcccagac agcgtctcga
    23161 atcaagacat caccaccagt catggcagca gctaccataa aggttcctgc ttcgatacgg
    23221 tcctggacta cattgtgagt cgtaccatga agtttctcaa caccagtaat ggttatagtc
    23281 tctgtaccag cacctttgac cttggctccc atttcattaa ggagaatggc taagtcaaca
    23341 atctcaggct cacgcgcagc attctcaatc actgtcaccc catcagccag agtcgctgcc
    23401 atcatcaagt tctgcgttgc accaacactt ggaaagtcca tatagatatg agcaccatgc
    23461 aagcgttctg cctttgcttc gatgtaacca gctgtctgac taatcttaac ccccatagct
    23521 tccagacctt tcaaatgaag atcaatagga cggctaccaa tcgtacaacc acctggcatg
    23581 gataccttgg catgacccac acgggcaagg attggcccta atacaacgat ggaggcgcgc
    23641 atcttactga catacttgta aggggcttcc tcagtgatgt cgccagtagc atccaccttg
    23701 acaagatgag cttcctcatc aaagtcaacc ttggcattca aaccaccaac tacctgattc
    23761 ataataaaga catccgacaa aatcggaaca ttctgcaaga cggtctttcc ttcacttgct
    23821 agaatagtcg ctgccaacaa gggtaagact gcattttttg ctccctcgat cgtcacgctt
    23881 cctaccagac gattatcgcc accttgaacc acaattttat ccatactcgt ttcctttact
    23941 cttgatttta taataatcct ctaagcgctt cttgccacaa atgatacagg ctaataaaga
    24001 aagaactcag gatgtagcct atgacaatgc taaaaaaggc tactaataca cgaacttttc
    24061 ttgtattctc agctgtcact tttaaaacct tttcccatct aacaagatcc tttaaaaggt
    24121 aaaaactcac ataaataaag agcatatgac tacttagagt gaataataat tgaaccattt
    24181 gactattata ccatcttctc tgtttgtgcg ctagtttgga aacttcactc aaaaattagg
    24241 gattgttttt caagtaatca atcgcatctt gtagggtttt aacgggcacg attttcatat
    24301 ccgtcttgat tgttttagcc gcttctaggg ctgtttggta gttgtttttc gcgtccggat
    24361 gcgccttttg ttcttcttcg ctaacagggt tatcaggagc aaagaaaata gcagcacctg
    24421 ccctagccga agctacaacc ttcttatcaa tacctccaat gtctcccaca ttaccatcgc
    24481 ggtcaatggt acctgtaccg gcaacaatac gaccattacg aagatctggg tgagctattt
    24541 gagtatagat agctagacta aacatgagac cagcacttgg gccgccaata ccagctgttg
    24601 aaaagctaat tgggacattg ctgattacct ctgtacgatc aatcaagccg attccaatcc
    24661 cattttttcc attttccaag gtgataatct tcccttctgc agacttggtt tgcccatcct
    24721 cttcataggt gaccttgacg gaatccccta atttttgaga actgacgtaa tcaatcaagt
    24781 ctttggaact atcaaaggtc tgatcattga ctgctgtgac tgtatcagag atattgagaa
    24841 tccctttaaa ggttgaatta tccgtcacat tcaaaacata aactccaaag tacttgagtt
    24901 cgatatcctt accagctgtt tttagtcctt gatacttggc catattttgc gatgtttgca
    24961 tgtagaattg attgattcgc ataaattcaa catcggaaga accacctgta gtctcctgag
    25021 cactacgaat atctgtaaaa ggtgtcaacc aagcataaat catatgagct aaagtagcat
    25081 gttgaacacc aaccgtaacg aattgatagg caccagcttc cttatcttct gtgtcattta
    25141 ctttaaggac ttggcgaata tcttccgaac cacctggaac ctctatataa taaggcaagg
    25201 gcactacaaa tgccaagaaa gtcacaatca aggccgcaat gacgtataag ggccatctaa
    25261 tctttttttt catttcttat ttcctccaaa atactctcgg gaacatagca ggcaatatcc
    25321 tgaccaaact tcaaaagctc tctaacgcct gatgaactga tatagagatg ttcaggtcga
    25381 ctatgtaaat aaatagtctc tatatcagaa gacagctgat gattgtagta atcaaaactg
    25441 gcttcatatt gcaaatccga cgcattcctc aaaccacgca ctagacaagt agcacccaat
    25501 ctttttgcaa catcgaccac caattcatca tgagaagcca cgacttcaac attttccaaa
    25561 tgtcccaaag ccttttctag cccccgttta cgattttcaa gagggagaaa tccttgtttg
    25621 tggggattaa aaaaaatacc cacacaaagc ttatcaaaaa gtctgctcgc ccgttcaatg
    25681 atatccagat gcccatttgt catcggatca aatgagcctg tgaataagcc aatcttatct
    25741 gacatagact gtcaccttac taattccata aatcttttcc ttccagatac ccagacaggc
    25801 aatttcttct ggaagttcaa cggtcttatc cgtctcgcac acaaccataa catcttcaga
    25861 aaaaagctct ctctcagcca ttttttcaat atctgctacg atttgttcct tggcataggg
    25921 agggtctaag aaaacgaggt caaattcccc agatacctgt tccaatgccc tttctgcatc
    25981 cattttgagg agttgaaatt ttccaacttc cttggtcatc tggatatttt cagccacgat
    26041 ggtctgagcc ttacggtctc gctccaccaa aacagcactg gacatgccac gcgatactgc
    26101 ttcgatagat aaaccaccac tacctgcata aaggtccaag actcgtccca cttcaaagta
    26161 gggaccaatc atgttaaaaa tggctcccct aaccttatcc gaagtaggtc ttgttgtctt
    26221 gccttctagt gtcttgaggg gacgtccccc atagattcct gatacgattt tcatactgtt
    26281 tattatacca aattatagac aaaaagagaa agaaaaccga accttgcggt tcgattctct
    26341 acaaaatatt ttcgtaagta tcgcggactt cttgaggcca aacacttgtt tgcacttctc
    26401 cgatgtgtct cttgcgaagt aggaacatgg ccatacgaga ttgtccaatt cctccaccga
    26461 ttgtcaatgg gaataggcca ttcaacaaag acttgtgcca ttccaattct aagcggtctt
    26521 catcacctgt aatttccacc tgacgtctaa gagtttcttc atctacacga attcccatag
    26581 aagacaactc aaaggctcca cctaaagact cattccagac aagaatatca ccatttagac
    26641 ccttgtagcc attctcagac tcgcttgtcc agtcatcata gtctggtgca cgtccatcgt
    26701 gcggtttacc atctggcaac tcgccaccga taccaatcaa aaagacggct ccaaattctt
    26761 tacaaatcgc attttcacgt tctttaggtg tcaagtctgg gtagcgttct accaattctt
    26821 ctgtatggat aaaggtgatt tgttttggca agatagactc gatgtcatag cgggcttcaa
    26881 cagctagctc agtcaggcga atagccttat aaatcttctc aactgtttct tttagataaa
    26941 cgatgttacg cttaccattt gggataacct tctcccagtc ccactggtca acataaacag
    27001 agtgggttgc atccaaggaa tcctcatctg gacgaagggc tttcatgtgg acaaagagac
    27061 cctctccttc accaaagcca aaacgagcca aggtgtggcg tttccattta gcaagtgagt
    27121 gcaccacttc ataagtagca tcagggattt ggagaacctt gaccgatact ggattttcca
    27181 caccagacag gttgtcctgc attccgtcac cgaccttact caagatagga ccttgaactt
    27241 cgacaacttc tagcttatct ttcaaatact gggtaaaagt gtttttgaca aaggaaattt
    27301 cttcttgttg atggataaaa cttttcttca tagacaactc ctcaaaaatt taataaacgt
    27361 attatacacc tatttccaag aaaagaaaag agaaaatttt aaaaaaatca gtgtcactca
    27421 aaacactgat ttcatagacc ttttagtcat tgcgaccaaa gatacgtaga atacttagga
    27481 aaagattgat aaaatcaaga tagatgctga gagccattga caccacccag cctgtcgcta
    27541 cacgaccttg tgattgttca taggcgaggc gaatcttttg gttatcccaa gcaatcaacc
    27601 ctgaaaaaac caaaaccatg gctacgctaa tcatataatc aaagaagcca ctagccaaga
    27661 aaatattgac taccatagca atcagtaaac caatgagagc tgccatcatt gctcgaccaa
    27721 tcccactcaa gtctttcttg gtaaaaatac caactgccgc catgacaaag aagagaaggg
    27781 cgctcgatac aaaggcagat aaaactgtac ccggagtata gaaagccacc acaaaactaa
    27841 gggtaaagcc gtttaaaacg gagtaaagta aaaatactgg aagagcagct ggactatttc
    27901 ttgaagccat gctactggca acgaaaacca aagccaactc cgcaaaagta gcaatggtca
    27961 accagagacg cccctgcatc aacaagtaaa ccaactgaga ctgaaagacc gtcaacataa
    28021 ggcctgatac caaagcagat agtccgattc ccagaccaac aaaggcataa accttagcgt
    28081 aaaattgatt gagacctgca cggtcatgta taatagtgtg attcatcctt ttctcctttt
    28141 ctgtgaacat ctttccttga ttataacaaa aaaagttaaa attagcttaa atggaagatt
    28201 aaaataccgg ctgcaactgc aacattcaaa ctctcggcct gccccttcat gctaatatgg
    28261 accaactggt ctgcactttc agccataagg ggactaattc cttgaccctc atttcccata
    28321 actagtacaa aattttctat agaaggcagt tctctgtaat caacagaatc tttagatagg
    28381 gttgttgcta gcactgggat agctaccttt ttagtttcgt caagaagcgc ttgactagtc
    28441 atccggtaaa tgggcagatg gaaatgacta ccttgcatgg aacgtagggt tttgagactg
    28501 tagatgtctg ccgacttatc tgaaacaatc actcctgtaa aacctgctgc atccgcagtt
    28561 cgaatgatag ttcctacatt accaggatct tgcacatctt ccaaaaacaa gaacttgccc
    28621 tgactcaaat cagcttgtcc tacttcttct ttttgaacca cggcaacaat tccctgtgga
    28681 gtctgagaat ccgccaaatc tagcaaaata tcctctgaaa tccagacagt ttgcggaaaa
    28741 gcagctaact gatttcgata attttctagg gcaaagattt tctcaatcgt cactccagct
    28801 tggacagctt cttcaaacaa gtgccagcct tcaatcaaat aggcagactt gcggtatttt
    28861 ttttggtgta atttcttggc attttttacc acagaattgg cttttgaggt tataatagtc
    28921 atagaaatat tataacacaa tcaaaggggt ttggtatgca aaaggttaga atgattgccc
    28981 aaggtagggt gcagggagtc ggctttcgtt ggggtgttta tagcctggcc cttgaaatcg
    29041 gtggcatcac aggtcgggta tggaataacg acgatggcac agtggaaatc ttagcccaag
    29101 cagactcatc tgctatcatg gcaaaattta tccaagaaat ccgaaaagga ccgacacctt
    29161 tttcaaaagt aagctactta gatgtcaaac taagcaactt tcctccctac tctgacttta
    29221 aaatcgcaaa ttaggtctcc agaactattg tatattttgt aaaaaaacag tagaatagaa
    29281 aggtataatt tttaaagaag gaataaaaac agtgaaatct attaaacgtt ttgcattctc
    29341 ggctatggga gtggctatgt tgcttgtctt gactggctgt gtcaatgtcg ataaaaccac
    29401 aggtcagcca acaggattta tttggaatac gatcggagcg cctatggctg aagccatcaa
    29461 gtacttcgct actgataaag gtctaggctt tggtgtcgct atcattatcg taaccattat
    29521 cgtacgcttg attatcttac cacttggtat ctaccaatca tggaaggcaa cgcttcactc
    29581 tgaaaagatg aacgctctca agcatgtcct tgagccacac caaacacgtc tcaaagaagc
    29641 aactactcaa gaagaaaaac tcgaagccca acaagccctc tttgccgctc aaaaagagca
    29701 cggcatcagc atgtttggtg gtgtaggatg tttccctatc ctccttcaaa tgcctttctt
    29761 ctctgctatc tactttgctg cccaacatac tgaaggggtt gctcaagcaa gctacctagg
    29821 cattcctcta ggttctccaa gtatgatttt ggttgcctgt gctggtgtcc tttactatct
    29881 tcaatcgctc ctttcacttc acggagtaga agatgaaatg caaagagaac aaatcaagaa
    29941 aatgatttac atgagcccac tcatgatcgt cgtcttctcc ctcttctcac cagctagtgt
    30001 cacactttac tgggttgtcg gtggtttcat gatgattctc caacagttta tcgtcaacta
    30061 tatcgttcgt ccaaaacttc gcaaaaaagt ccgtgaagaa ctagccaaga acccaccaaa
    30121 agcaagtgct ttctctaaac caagtggacg aaaagacgtt acccctgaac aaccaactgc
    30181 tatcacaagc aagaaaaaac acaaaaatcg caacgctgga aaacaacgtt cgagataaga
    30241 agaaaaaggc ttagctgatt tgctaagtct ttttgcaaat caaaagcccg atgtttccat
    30301 caggcttctt ttctatccat gtacacgttt catataatct tgataacttt cggtatccat
    30361 gagtttttta gcgttcttga cgcgatctgc tgttggtggt ttgactcctt cgagggaata
    30421 tggaattcca agttcacgcc acttgaactc acccatggtg tgataaggta gaatttcaaa
    30481 cttatcaaca tttttgaggg tcttgacgaa cttaccaagt tcaatcaagt catcatctct
    30541 gtctgtcaat cctggaacta gcacgtggcg aatccagaca ggttttccaa tatctgatag
    30601 atactgggca caagccaaga tatttttatt agtttggcta gtgacaatct tgtgctgttc
    30661 ttcgttgatt tccttgatat ccaaaagaac caagtcagtg acagccatga gtttgtcaaa
    30721 cttctcaagg taacgtggtt tattacggaa aggaagagca caggtatcca aggtacagtg
    30781 gattccttgt tccttagcct tggtgaagag agcaatcagg aaatcaatct gcaagagagc
    30841 ttctcctcca ctgactgtaa tcccaccctt atttccccag aaaccacggt agcgcaaggc
    30901 ctctgtcaag acatcatcta ccgtccgttc acgtgactta ttggactcca tagcccaagt
    30961 gtctgggttg tggcaatact ggcaacgcat gtgacagccc tgcaaaaaga caataaagcg
    31021 aataccaggc ccatctactg acccaaagct ttctgtcgaa tgcaccattc ctgtcacttg
    31081 tccataatca attgtttctt cagacatatc gttaccttcc ttgaaaacgt tttatagttt
    31141 tattatatca cgacttgaag gaaaaacaag atttttgcct attttttaga aagcaatctg
    31201 tttttcaatt tcattttcaa tctattatca gattattctt caaaatcgaa gccatataag
    31261 gttgcaaaat agtcctcagg gcgctctgca cggcggattt gacgggcttt accttcttcg
    31321 gtatagagga tttccgcaga acgtaatttg gcattatact ggtagcccat tgaaaatccg
    31381 tgggcacctg tatcatgaat taccagcaaa tcaccgattt ctgtatgagg cagttcgcga
    31441 ttgactgcaa atttatcatt gttttcacag agtgaaccaa ccacatctac cgcttcagct
    31501 ggtccatctg gatgggtcac gttgctaata tgatggtaag ctccgtacat agctggacgc
    31561 atgaggttga ctgctgaggc atccacacct agataggtac ggtaggtttc cttcttatga
    31621 gtcactcttg tgactagagc accgtgaggt gccagcataa aacgacccaa ttcggtgaaa
    31681 atcttgacct gaccaagacc tgctgacgta agaacttctt catacacctt acgaactccc
    31741 tcaccaatca aggcgatatc gttcggctcc tggtctggac gataattaac accaataccg
    31801 ccagaaagat tgataaagtc tagcgaaatg cccaactttt ccttgatttc aacagccagt
    31861 tcaaagagct gacgagccaa ctctggataa tagagatggg tcacggtatt ggacgctagg
    31921 aaggagtgaa tcccaaaagt cttggctcct ttttccttca agatagcaaa ggcttcaaag
    31981 agctggtcct tggtcatgcc aaacttagcc tccccaggat tgtccataat gtctgtcccc
    32041 agttcaaaaa cgcctccagg attataacga caagagatga tttctggaat gcctgctact
    32101 ctctccagat gttcaatatc ttcaaaggca tccaagttaa tggtcgcacc caattcacgt
    32161 gcataggcgt attccttgtc tggcgtgttg ttggaagaga acataatctc agaacccaga
    32221 aagtccagtt tatggctcat caaaagctct acataactag agcagtccac accacaacct
    32281 tcttcttgga gaattttcaa aatagctgga gttggagtag ccttaactgc aaaatattcc
    32341 ttaaagccct tgttccacga aaaagcttgg ttgacggctc ttgccttctc acgaatcccc
    32401 ttctcatcat acaagtgaaa gggagtcggg aactcggcaa caatcgcttc taactcttct
    32461 ctattgataa atggtgtttt cataagcttc cttctattct gtttgcaaag aaaggctggg
    32521 acaatcgttc caacctttag ttctatctct tatttatctt cgtcaaagat attgccaacc
    32581 tcaacatcga tggcttggtt cttgacatca atattggtta ccttcaagag tgacttgtag
    32641 tcaaactgct tttcacgttc ttcttgggca ttgtccgcaa agaccgctac acctgccagt
    32701 tctgagtcga actcgtgcaa gagactaatc ataccattga ccgttccgcc acctttcaag
    32761 aagtcatcca caatcaagac acggctgcct gccttaagac tacgttttga aaggaacatt
    32821 ttctcgatac ggtcaccact tgaacctgaa acatagttga cgctaacagt tgaaccttcg
    32881 gtaattttca ggtcacggcg cacaatgaca aaagagacat tgaggacatt ggcaactgca
    32941 tttgcaagtg gcacaccctt agttgctacg gtcataaccg cgtcaatttt ttggtccata
    33001 aagcttttgg caataatacg accaatattt ttcaagatgg ctggtgtgct aagcaaatca
    33061 gacagataga tataaccacc tggcaagata cggtcacttt ctgacaactt ggtacgcaag
    33121 tcttcaacca tttccttagc atcctgactc gaaatagacg gtgtgaagat gacacctccg
    33181 ccagccccag tcactgtctg gatatgaccg atttcaattt cctcaaaggc gcgtttgata
    33241 atgacgatat cttctgagat ggatgattta gcagactcat acttttcagc aaaagtattg
    33301 agactagtta gtttataagg attattaatc aaatagttgg aaatgacaac catccgatca
    33361 cttcttctta atttcatttc tatttcctat tccattttta ttcaaaaaat caaaaagcaa
    33421 actagaaagc tggtcgctgg tggttcaaaa cactgttttg agattgtcaa tagaactgac
    33481 aaaccctgta atatacctgc atatatacat acgacaaggc gatactaccc tagtttgaag
    33541 agattttcga agagtattca tttttgtctt ttacttatta taccatattc acataaaaaa
    33601 acgaacattc ttatcctaaa aaatgctcat ttttcttaaa ttatcaatct aaatctggtt
    33661 tatagaagga acgattatcc atagcgaaga ttttattggt catctctcct ttatccacca
    33721 aagccagagc tgttgacatc atcatcatgc ttgcatccag attgtcaatc atatggataa
    33781 tctctgcctc cataatacgt ggacggactg gacttccata ttcaagcaag ccgtggtgac
    33841 tgaggatgac atgacgaagc aaaacgactt cttccttggt atcatcgatg ccgagttcca
    33901 taactgtctt ggtaatttcg ctatcaatga gagcgatatg tccaagaaga ttacctcgca
    33961 ctgtgtactc tgtctggtct ggccccgtca actcgataac cttagctaag tcatgcagca
    34021 taatccccgc atagagcagg ctcttattga gctgaggata aacttcgcta atagcgtctg
    34081 ccaaacgtac catggtcgcc gtatgataag ccaaccccgt ttcaaaggca tggtggttgg
    34141 tcttggcagc tggataggag tagaattcct tatcatactt ggtgtagaga tttcggacaa
    34201 tccgttgcca gacaggattt tcaattttga aaatcatttg cgacatgtag tcacgaattt
    34261 ccttgacatc aactggtgac ttgaccttga aatcggctgg gtcattgggt tcaccagctt
    34321 gaggcaggcg gagagtaatt tgattgactt gaggggtatt gttataaact tctcggcgtc
    34381 ctttcatgtg gacaacctta cctgcggtaa aggcctcaat gttatgaggt tgggcatccc
    34441 agagcttccc atcaatctcg ccactatcat cttggaaggt aaaggctagg tagtttttcc
    34501 cagctcgagt ttgcctcagg tcagctgatt tgattaggta aaagccttca aatagctcat
    34561 cttttttcat gtgactaatc ttcatattct tcctcatttt cttgaaaatg gagtagatca
    34621 agcgcaggct caccttctga caactcaatg tgacggagcg tccgctcgat agctatggta
    34681 cgacggttta ataattcatc aatattgcca gaggcatgtt ggagatgttt ttgtgccttg
    34741 accagaatac caccaaactt gccaaactcg gtcttgacac tggcaagagt cttgctgata
    34801 tggtcggcac tcttttggat attaagggtc ttgaaaccaa ctgatagaga gttaagaagg
    34861 gctgataggg tacttggtcc tgcaacaata atctgttctt cccgtctcaa atcatcaaag
    34921 aagaccggat tgcgcacaat ctctgaataa agaccttctg tcggaacaaa caagattcca
    34981 aagttggttg tccgaggtgg tgctatgtac ttgttcctaa tatccctagc aaagcgcttg
    35041 acgcttgcta ggagtgactt acgacagcgt tcaatctcat ccttgtcacc tgtctcatag
    35101 gcttcttcca agcggtaata atctgccagt ggaaacttag agtcaattgg cagatagacg
    35161 tattcttggt cgccttgtcc gggtaacttg atggcatact ccactcgttc actagagttt
    35221 tcaaccgttg cgtattctcg ttcgtactgg gcaggtgtca tgatgtcttc aataatttgc
    35281 cccagttgca attctcccag aatccctcgc gtcttggttc cagagagaac cttgttaaga
    35341 gctccgacat cacgggcaac tgtctgcatt tctccaaggc cacgattgac agactccagt
    35401 tgtttagaaa ctgtctcaaa ggaagcctgt aagcgtgtct gcaaggtctt ttctagtttt
    35461 tcctcgaccg tctggcgcat ttgttccaaa cgttgctcat ttgattcctg caaggcttgg
    35521 agacgttggt ctgtcttgtc tctagtttgg aggagattat ctgtcatttc ttgacggact
    35581 tgggtcagac cttggtgcaa ttcaatccgc acttcttgca aacggtcgct gacaaccact
    35641 tccaaatctt tttggtctaa ctggctggct tgtctggctt ggtcaaagcg gtaatccaac
    35701 tggtctgaca aatgatctgc ctgatcctcc aagctcttac ttaagtgttt ctcctgccta
    35761 tcctgccttt gccaaatcag aaagagacca gctagattgg caattaataa tagaataagt
    35821 aaactttcca tcctacctcc tgtccttgct atgcagtacg accacataac catctgggca
    35881 agttaccgac acttccctat ctatatattc gttagaagcg tacacttttt taaagaaaaa
    35941 attttcctct gtcaactcat acttggctcc aagaatagtc agctggctat cccgaactgg
    36001 cataaaggct agatagtcgt agtctgaacg aggttctagc tgactgattc cttctggaca
    36061 ataagtaatc aagttttgcc catcctcaat ttctatttga tgcatatagg atgccaactt
    36121 aggattgcta ggcagaaaga cattggccaa catatggtca atacggccac ccaaggcacc
    36181 gaaaatagta acctgagcct gaggattttg cttaaagatg gtcaagagag ccaattccaa
    36241 atcagtatca tctttttctg gccgggcttg gacaaaatac tgggcacgtt tttgaatcac
    36301 ctgtcgctct tcttccgtca cagaatcaaa atctccgact gctagagcaa gaggcaaatc
    36361 ttcttccaag atccagagcg agcctcgatc cacaccaaca aaaccatcaa agtccgtccg
    36421 ataatgaccg cggtctccgc ctgcaaaaac ggcaacccta gtccagttgt tttctgagag
    36481 tttgtactcg ctcattgaca tctcccttaa agacatagga acctgctaca aaaacggtcg
    36541 caccagcttc tttggcttga gcaatagttt ggtcatcaat cccaccatcc acttcaatct
    36601 caaagttcaa acctttttca tcacgaaggg caaccagctc acgaacctta tccatggttt
    36661 ctggcagaaa ggcttgacca ccaaatccag ggttaactgt catgactagg acttggtcaa
    36721 ctagatgaag cacatgctta atcgcttcaa ctggtgtacc aggattgata acaactgatg
    36781 gcttgacacc gagtgaacga atcttttgga gggcaccatg aatatgaggc gttgcttcca
    36841 catggatact aataatatcc gcacctgcac gcacaaagtc ctctaaatga tgctcagggt
    36901 ttgacaccat caagtggcag tcgaaaacca tcttactatg aggacgaaga gcttcgacca
    36961 cacccgcacc aaaactgatt tgcggcacaa aatgaccatc cataatatcg atatgggcat
    37021 actctgcccc agttgcttct aggcgtttaa tttcacgttc aaagttggca taatctgctg
    37081 ccagaattga cggagcaatc ttgtattgag acataggttt ctccttattt tggaattttt
    37141 ttgctgactt ttttataggt ttctctgcga ttttcaattt cgctgaggaa ttgcaggtag
    37201 ttgtcaaaac ggaagggcgc aatggtacct tcttcaactg ctggcttgac agcacaggac
    37261 ggctcatggg tatgggtaca agtacggaat ttgcagtctc gactgacagt ggcaatctct
    37321 ggaaaggcct gattgaggtc ttcagccgtt gatacttcat aatccagtga tgaaaagcct
    37381 ggtgtgtctg cgattttacc cccattgagg ttgtaaaaac taacagctcg agtggtatga
    37441 cgcccgcgac ccagactgtc tgaaatttct cccgtttcaa gattaagatc tggtgcgatt
    37501 ttattgagaa gagttgattt cccaacaccc gtctgcccca taaagaccgt aaccttgcct
    37561 gttaacaaag gcaggagttc ctctttactg gtcacaaagt catatccgat gtcaccatag
    37621 gtctgctggt aaaaatccag ttctcccccg tcttccaaca aatccatttt agaaatatag
    37681 acgatgggat gaataccctt atgctccaaa agaaccaaga aacgatccag caaattgctg
    37741 ttaaaatcag gttccttgac agacatgatt actacagctt ggtcgatatt gacaataggc
    37801 ggacggacca gactgttttt ccgttcgtga atcttgagaa tatagccttc tgaattttcc
    37861 tcggcagaga aatctaccca gtccccaacg taaggggtat gccctttttt acggaaattc
    37921 ccacgcgcgc gtgtttgata gacttggcca tcactctcta catagtagaa cccagccaag
    37981 gctttaatga tttgtccctg caaaataact cctttaaaat tgttagttcc attataacaa
    38041 aaaaaagcta ttttagctta gcttctcttt acaatttcga taagtctatt ctaaaagaaa
    38101 aagatacact cacgctttag ataccaagtt ttatacaaaa ataacgaatc tacctcctta
    38161 tataaaaaca ggcgaacaga gagcctaaaa ctccctgttc gctttacttt ttctgtgtgt
    38221 aatagaaaaa acctaataaa gcaagacaaa aaatatgaat ataaactcca tacatcatgt
    38281 ggggaaagac agactctata aaatagcctg gtagatagat gattggaaat tgatagaaat
    38341 cataggtcgt tagagatagt aaacaaagaa catacataaa tactgctaca attagaaccc
    38401 atccttgctt tcgccataga aaaatcatca ataagaacag acaaagtaga tagattgacc
    38461 aatttcgcaa cataaattga aaaccataaa tcatactttc agtcgtttct ccatcaatca
    38521 catcaactac tttatagaaa ggtaaacaat agctcactaa aaaaagaagg ggactaatta
    38581 tttttttcat attctctacc atggattatt ttgcaagtaa gctgaccatc tatctccata
    38641 tcgaatcaaa ttaacagtat aattagttac tacccgattt tcacctggtc caaccttaga
    38701 aaaacctgtg ctatactccc aactacttct tgcacctgga tgaaaccatt tttgctggga
    38761 tgaataccaa ccaccttgtc taacttccac acttgaagat tctatttcga tatccctttc
    38821 atggaagtca actcctccac ttattttagt aatatttttt tgtacacctc catcataact
    38881 cacccagtga acaacagtat acaattccac actataagta ctatcaaact gactttgatg
    38941 agtagtaatg ttttgagtat aagcgtgcac tttctgtata ccaaaaatat ggtctaatat
    39001 attcgttggt ttagcaagct tattgtaacc ctcttcaaca aaagtagcct tctctaaatc
    39061 agcggtataa acagtttttc cttgtactac ttgattgttt atagaagtaa tacggctatc
    39121 cacaacaatg ggggccacca tatctccatc gctagtttct attttagctg cctctttcac
    39181 ctcatataca actcgatttt cttcagactg aatcacttct accccatttt tttcaggtat
    39241 agataatcta gtttgcccat tagaaaccgt tatatttgga ccaatattct tctcatttgc
    39301 ataagtcgca ataggaaatc ctgatagaac cactgcacac ataaggctat tgactaattt
    39361 ttttctcatg aatatatcct tcccattttc aagaggagta aaaatagcta atataagatg
    39421 aacgtttcct tatatttcag aataggatat ctatctgaaa gcaattcaca ctcctataga
    39481 taactgttcc aaatcttggc tacatatatt tcaatagttt gctacaaaaa actcctttct
    39541 aagtctattg aacatgccct tattcaccta ctaatatatc acaaaaataa ataaatacaa
    39601 gactgttttt tctactagtt ttatgataga atagtattgt tagggtaaat ttcatatata
    39661 aatgtcgagt gaaaaatcga tggagcagaa atcggtagac aaagactcga tttcgttggt
    39721 ccagccccac aaggctaatc aggtatttca cgagtttaaa aatctaatga agtgcccaat
    39781 caactactga ttcattgatt taatacgaac tatagtggat tgaacctaga aatagtacac
    39841 taaggattct aaaacgtttc tagaaattaa tttgactttc ctaatctctt tgttcatatc
    39901 ttatttcaat ctactatata taccaaaatg ctaggacaaa agtctttaaa atcagagaaa
    39961 cgcatattat caggtgttgg aaaaccttga taatatgcgt tttatcatag aaagatctac
    40021 ttcatttttt actaaaatta agtttttgtc cctgcatctt agagtccttg ccctttaagt
    40081 gcatctgcta ggctggcaaa ctcttccaag ctgagagctt ccccacgcac acttggtgac
    40141 aagcctgctt ggtccaaagc cttggtcagc ttgtccttga cctcttcagt cttgccaaag
    40201 taacctgtca agttattcca caaggtcttg cggcgatggg taaaactagc cttggaaacc
    40261 ttaaagaaaa agttctcgtc ttccactgct acagctggca ctggacggcg caccattttc
    40321 aagatggctg agtctacatt tggtgctggc acaaagactg tacgcggcac gataaaggca
    40381 accttggctg tcatgtaata ctgcacagcg atagacaagc taccgtaagc cttggtattt
    40441 ggttgagccg agatacggtc cgccacttct ttttgcatca tgaccacaaa ctcactaaaa
    40501 ggaatgccac tctcgattaa gtgcatgaga ataggcgttg tgatgtagta aggcaaatta
    40561 gccactacct tgattggcag gtcaggattt ttgaaattct ggatatgttg cgccaaatcg
    40621 accttgagaa tgtcctcgtt gactacagtc acattgtcaa aatcacgcaa ggtatctgcc
    40681 aaaatcggta ccaaacgatg gtcgatctca aaggccataa cttctgctgc acgctcagcc
    40741 aaaaactcgg tcaaggcacc aatacctggc ccgatttcaa tgacattgac ctggtcatca
    40801 atctcagccg tatccacgat tttttgtagg atattggtat ccgtcaagaa attttgccca
    40861 aaggactttt taaaggtaaa accgtgacgc tccagcactg ccttggtcac gctataatct
    40921 gcaattctca tctattctct tttctattat ctgttactac tattgtaaca cattcccctt
    40981 gtattttggg ggtgaaaatc ataccaaaaa actatctttc ctcatgaaga aagatagtct
    41041 tggaaatctt taaaagtggc cttagcgctt ctctcgaaac atacgttcat actcttcgaa
    41101 aatctcttca aaccacgtca gcttcacctt gccgtactca agtacagcct gcggctagct
    41161 tcctagtttg ctctttgatt ttcattgagt atcaaaaaaa tcagcttctt gataacttcg
    41221 attttcgggt agggtcaaat ccacatcctc ctccacatca tccactgtca gttcaaccgt
    41281 ttgaggtaaa tttttcaaac gataatgctt ttgcctttgc ccttcactac tagcaaaatc
    41341 aagcaaatag ccatgcactc ggatttgaac caaaaggaga ggattggtca tattttccat
    41401 gatgaggata tcttataaac cacctctggc actaggataa tcagataccc tgcgaatacg
    41461 gattttttca cacatgagca agtttcctca tatcaatgat ttcatcagcc ttattccaga
    41521 ctaggggatt atgggtcgca atgatgataa ttcgattttc atctttcaaa tccaccaaga
    41581 gattcataac ctcctctgaa ttttcaggat caagagctgc tgttggttca tctgccaaaa
    41641 tcaagggtgg atttttcaaa atagttttcg caagggcaac tcgttgggcc tctcccccag
    41701 ataaagtata aattttttgt tctaaatcca aataccctag attaactttt tctaaagccc
    41761 ccacttgcct ttccaaacgt tctacttttg agattttctg accaacaaaa cccaaatcca
    41821 aattttcttt gattgattgg ttttctaaga ggccaaaatt ttgaaagaga tagcccatct
    41881 gatctcgaaa atactcacga gtgggaatgg tttttaaatc tttcccctga tagagaaccc
    41941 ttcctccatc tatcttttct agctttccca agatattcag cagcgtcgtc tttccgcttc
    42001 cactctttcc gattaaggca taaaccttgc ccttctccag cttgagattc aaaccagaga
    42061 aaatcgcgcg gtcattaaat ttcttttcca atccttgaat atcaatcatc ttattttcct
    42121 ttcaatactg ccatgctacc agcttcttct tttttgtcct gccttactaa aatcaagagg
    42181 gcgttaagcg taaacaaagc tacaactaga gcgctaatca aaccatctct tgtcaaaata
    42241 ctagatagga ctaggccaag caagagaact cctccttgcg ccagtaaata cttgccatga
    42301 agctcataga ttgtcatacc agcaagacgt ttaatcataa gctcccgtct gaactgctca
    42361 aaatagagaa gattcatgga atcaaataac aagatagccg tagacagggt caaaatcgtc
    42421 ccaataagga gagagtaaaa ctctacccgt ttgtcattta gtaccttggc aaaaaatagc
    42481 tggcttttta ccaagtaaga aaccttgtga tacagacctt gctcttttag agctgtgatg
    42541 ctgtctccat atcgatctag tttcaaggca ctattagccg tagttcccca caacatccct
    42601 gcaacaggtc ttgttccagt cgcttgcggc gttagaacta caataatcgg atcttttagg
    42661 tactggcgtg ttgtcttgta cccatcatta tagaggaaac gttcctgtcc tgtttctgta
    42721 aaagctagac ttacctgtgg gaggtagtat ttctgactcg tcacttctac actttcagat
    42781 gaaaagtttt gcaggtaatc tgtaaacaat ctttggtagt aggtagactg ctctcgcaag
    42841 ctctcaggca agattagccc aaactctccc tcagacaagt tttgcatctt gtccataaac
    42901 tctgaagaaa cggtaatctt ttcttctatc agatagcgtg gtgagacata gataacattc
    42961 cctgacggtg tgtagtcact gagacgattg ccatctaggt ccacttctgc tccgtctgag
    43021 aaattgtcaa cattgctcat aatataaaaa gagtctgtat tggctaaccg ttcttcagta
    43081 aatgtctgcc actcacgatt atccttacgc gttccttctt catcggcaaa tgcactagac
    43141 caaccaaagg atagacggta acggtctgag gactggctcc atttattgct agctctctcc
    43201 atttcctgca tttcacggta gtggggtagg agagctgtcg cactcgatcc gaccaccaat
    43261 acagctaaga gttgccccac catcatcaat gtcatcatac gtttgagagg gagtttccct
    43321 ttcaatagat ccaccagact attttcctgt aaaccaagta gatagacgac acttagtaag
    43381 gtagaaatcc ctgccagggt caatccataa agtagaagag caatgatgac cagttgcacc
    43441 gttgccataa acaaggcacc ttgataccag agaatcccca atcccaaaag actggatacc
    43501 agcactgagc agataaactg tctcacatct tctaacactg gtctgagagc aactccaaac
    43561 aagctctcac cagctattaa gcgaatccct gcctgacgaa gggatttgat ccgataaatc
    43621 agggtcagac tcataaaggt cagcagaaaa atagctaaac tcagtagcac cataggggtg
    43681 gccgccaata gtaagactat cgaaaatgga tcttctccat tcgaaacaaa gccttgatag
    43741 ccaagttctt tcaaggtggt ctgtaagctc actccatcca aacttcctga cacaatcaag
    43801 taagacccta ataaatcact cgtttctgca ctctccttgg aggaaatggt cagaccttct
    43861 ggaagctctc cctcaccata agtggcatag gtaaagagtg tttctccagc ttcatttggc
    43921 tcaacgattc gacgggcgat gagactatta tgctctaccg ccaagtgact caaaacctct
    43981 gtcacctctt cgcgactagc tactggttga tttatcatca ttcctgtcac atcaacagaa
    44041 ggatagttac caaataaaat ctcttctcga tggtcaacgg aagttatcac catataaagc
    44101 gataccaata ccattgaaat caaaataaat aaacgtttca tcatttcctc caaaaagtta
    44161 cttggtcact tagtgagaag gtgaccacag tcactgcgat gttaagaagc ttattaagtt
    44221 ctttctacta gcaacatctt caaatacatt atatccgttt tttcaagaac tatcaaggac
    44281 atcaatgtcc ttaaaatcta actatttcat attattttta gcttatatct aaaaaaacag
    44341 ttctaaagac gaactttaga actgttttga tacgaggaca aggacatttt tgtcactgat
    44401 tcactatgtt tataaatatt ttttgacatc ctcttgccat tcctctgtca atttctttac
    44461 tagaaatcca tctccaatta gcttcgcaaa tgttttagaa gactgataaa atgattcagc
    44521 taaactaaaa tctctttctt ctcttaatgc ttgcttccac aaaaacataa atacaagagg
    44581 tttcttttga taatcttgag ttttatccat aatttcttgt aaacacgata gataatcatt
    44641 aaaacaatca gttactccta ccttttcaag acaacacatt cctgaaataa gagtatctct
    44701 aattataaag aagttttcta atttagttac ctttttctgt tccaaaagaa agagcattag
    44761 cttttcgatt tgatttataa atttggcaag atcttttcta atgagcattt gataaaaaaa
    44821 caaacgaatc aacaacatat catttgttga ataaacttct ttttctatga tctgagacat
    44881 atgttcctca agtattaact ctgcatattc aggccttcta gttctagaag tatccaaaca
    44941 cgcctgcaat acttcacatg ctaattgttc ttctttagga agattatcaa agtatgtttt
    45001 ataaatctct tccaaacacg cttccttctt atcgtactcc tcttctttac catagattgg
    45061 ttcacgtaaa atctggtatt tcaattctaa ataagcagga ggaagagctg aaaaatccgg
    45121 cataaggcta taaactggaa ctcctagccg gcgagcaata taggctaact tgggcaaact
    45181 cggttgcgaa gctccacttt caattcgcga cagttgacga actgtcagtt cttgctcatc
    45241 tccacaaaaa tatggacgac taactccttt ttctatccga atctctttaa ttttttgacc
    45301 aattaacatc agacgcctcc tcttctacct gcttcgaaaa atactgtgaa acttaaaaaa
    45361 ttgtaacggc tacatctttc ctactcataa gatttcatag cttcttccac ttctgccaaa
    45421 gtaaccccaa acaactctag gcgtttgagg agttgcttgc cgttagaata gccgattcgg
    45481 agagtctctc cgagatattc tctacgctta cggctgtctg cccctgctag aaaaccaagg
    45541 cgaatcaagt cgctacgact aatgtcaaac tgactctcat gttcaaattg ttctgtcacc
    45601 tgagctagag ccgttttcag gtcttcatag ctggcatgct caattcccag agaacgcccc
    45661 ttggtcttgg actttggaac agcttcatct cgcttgagaa aggcatgccg aactgttgga
    45721 atggccgtca taatcatgcg ccgaatccgc tccccattaa aatctgggtc tgtaaagaca
    45781 atgactccct gacgttggtg caggcgctga atccgctcta tatcctgagc attgatggca
    45841 gaacctcgag tctcataggt ctccacatcg aaataacgtt tgagattgac cgtatcatca
    45901 cgcccttcaa ccacgataac ttgagaaatt ttctctttca ttacttgctg tccaatccaa
    45961 aaatgcgttc tgcatttgca gtcgttgcta ccgccagctc ttctgtcgtc ataccacgca
    46021 agtcagcgat aaagtcgacc acatagcgag tataggctgt tttattttca cgaccacgct
    46081 tgggtacagg tgctaagtaa ggcgcatctg tttccaccaa aatcttgtcc aaaggtaact
    46141 ctttagctgc ttcttggagg tcagttacct tcttaaaagt caccactcct gagaaggaaa
    46201 tggtcatacc aagatccaca aacttctctg cccactcaag cgtccctgaa aatgaatgca
    46261 tgataccacc acgaggacca acgccctcac tcttgataat ctcataggta tcttccagcg
    46321 catcacgggt atggacaaca aaaggcaaat ccaagtcctt agatagctga atctgacggc
    46381 gaaaaacctg ctcctgcacc tctttgggcg ctgtcatcca atggtaatct aagccaattt
    46441 cacctaaagc cacaaccttg ggatgtttta acttatccaa caagtaagcc tcaacttcct
    46501 ctgtataagt accagcttct gtaggatgcc aaccaatagt cgcatagagc tgatcatact
    46561 catctaccaa ctccaaggca cgctcaatcg tcggtttatc aaaaccaaca atattcatct
    46621 gtgtcacacc catctcagca gccaaggcaa tttcttctgc ctcacgacct gcaaattctt
    46681 ctacattcaa gtgtgtatgt gtatcaaaaa tcatctcttc taacctcgtt ttctatcttc
    46741 tattatacca aaaaagagga ggggcaccta atttttcggt ttcccctcct ctcttcaata
    46801 gagagctatt ctgctatctt ttctatccga tattgcccat ctcctattcc acagttagag
    46861 acagaagaga ttggctacat tgatagaata ttcctattca gctaaagtat gtgattatct
    46921 tgggttctca cttttctcac ccatcactag gattgatgac ttctcaaaat cccccttata
    46981 atctaacttt aagtagagaa tagaattttc tagctgttct attttctacg tctagtcttt
    47041 cttcctagca aagcaaaacc acttgttgcc accactagac caagactagc aagtgctgca
    47101 cttgatgctg aacctgtgtt aggtaattgt ttgccagcag gtgactggta ggtaacatct
    47161 tgcattgttc ctgcagttgc ttgcggtgca cttgttgtct taggagcagc attaggagcc
    47221 actggtctct taggaactgt aaccatgaca atggcttgca ctccaatcgt ttctgcttcc
    47281 ttcacatctt ccatagtttt cgcattttca atctctttga gagctgcttg tttttctgct
    47341 tccactcttg ctaaaagttc tgctttttct ttatcagaaa gcggtgcgcc tttgatttca
    47401 tcctgcttgt ccttggctgc tttttcaatg gcatttttag ctgattcttt ttcagtagct
    47461 aattgcttag aagcttgtga ttgagctgag ttttgtgaac ctgtgtgagc tgatccaccc
    47521 gcctggctac caccgcctgc attcgcatta gcatctgagc ttccagtatt gcctccctta
    47581 tctccacctg gtgtattttc tagcttatac tctggtgtag cttcttgagt tacagattca
    47641 cctttcgcag attgttgaac tgtatctttt cctagaatcg tcactactga accatctggg
    47701 aatgtgattg ttgctgtacc atctccagct acattgattg tcgctccgtc taatgctgaa
    47761 ccatttgctt gtaaaatagc aaccttaact ttttcttcat ctgttaaatg agttatatct
    47821 tttacatcta ctctttgagc aggtgcttta acagttgatt tttcagcagt cggtttagtg
    47881 ctatcttgtg cttttggatc ttgtgctacc aattgatttc ctggaattgt aatagctgaa
    47941 ccatctttaa agacgattgt cgctgcgcca tctccagcta cttcaacttt atagtaaaat
    48001 gaaataataa caggacaaat cgatcaggac agtcaaatcg atttctaaca atgttttaga
    48061 aatagaggtg tactattcta gtttcaatct actataacat cgcttccgaa tccatttgca
    48121 tctactgaac ttttttacaa aaataaaaat cagtagactc gagttcctac tgatttttga
    48181 tagaattcgt ttggattatg cagccaaaac tttgcgtcct ttacgacgac gagctgccaa
    48241 tacgcgacga ccatttttag ttgacatacg gttacggaat ccgtgtttgc gcgcacgacg
    48301 aagtttactt ggttgataag tacgtttcac gatgaatacc tcctcataga ttttgtattc
    48361 gtttagccgg ctataaagtg atcagttact aaacatactt tactattcta tctgattctt
    48421 tcacttttgt caatagctct aggcaaatgt ttccagcttt ttcgaatgca agcc
//
LOCUS       DAVBCA010000008        45847 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.008, whole genome shotgun sequence.
ACCESSION   DAVBCA010000008 DAVBCA010000000
VERSION     DAVBCA010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 45847)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45847)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45847
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.008"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(1..186)
                     /locus_tag="VQU19_000412"
                     /pseudo
     CDS             complement(1..186)
                     /locus_tag="VQU19_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(248..697)
                     /locus_tag="VQU19_000413"
     CDS             complement(248..697)
                     /locus_tag="VQU19_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HET2479722.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            complement(699..1457)
                     /locus_tag="VQU19_000414"
     CDS             complement(699..1457)
                     /locus_tag="VQU19_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HET2479723.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            complement(1572..3551)
                     /gene="pknB"
                     /locus_tag="VQU19_000415"
     CDS             complement(1572..3551)
                     /gene="pknB"
                     /locus_tag="VQU19_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HET2479724.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSVE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            complement(3548..4288)
                     /locus_tag="VQU19_000416"
     CDS             complement(3548..4288)
                     /locus_tag="VQU19_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HET2479725.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVFMNEEDAE"
     gene            complement(4303..5616)
                     /gene="rsmB"
                     /locus_tag="VQU19_000417"
     CDS             complement(4303..5616)
                     /gene="rsmB"
                     /locus_tag="VQU19_000417"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HET2479726.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANNSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVEDRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            complement(5609..6544)
                     /locus_tag="VQU19_000418"
     CDS             complement(5609..6544)
                     /locus_tag="VQU19_000418"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HET2479727.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEELMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            complement(6557..8953)
                     /locus_tag="VQU19_000419"
     CDS             complement(6557..8953)
                     /locus_tag="VQU19_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HET2479728.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLKSQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGTVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSRSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            complement(9019..9333)
                     /locus_tag="VQU19_000420"
     CDS             complement(9019..9333)
                     /locus_tag="VQU19_000420"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HET2479729.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            complement(9358..9984)
                     /gene="gmk"
                     /locus_tag="VQU19_000421"
     CDS             complement(9358..9984)
                     /gene="gmk"
                     /locus_tag="VQU19_000421"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HET2479730.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            complement(10114..11727)
                     /locus_tag="VQU19_000422"
     CDS             complement(10114..11727)
                     /locus_tag="VQU19_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HET2479731.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            complement(11918..12172)
                     /locus_tag="VQU19_000423"
                     /pseudo
     CDS             complement(11918..12172)
                     /locus_tag="VQU19_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152757.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
     gene            complement(12176..12430)
                     /locus_tag="VQU19_000424"
     CDS             complement(12176..12430)
                     /locus_tag="VQU19_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HET2479732.1"
                     /translation="MEAVLYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVLSKS
                     EWDSIQETLRIAQNKELSDKVLRGMAQVRAGSTQVHVIEE"
     gene            complement(12668..13765)
                     /locus_tag="VQU19_000425"
     CDS             complement(12668..13765)
                     /locus_tag="VQU19_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HET2479733.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILDRLGIDSLVFGTEEVLD
                     YQKIADLYTEKGAEMEKFVKNLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLTYILVQARENVLPEAIHVLGFTEKVRQHLKSLKGQVNLVSRIGKEPWDA
                     MTQKADQIYQLGKPSIAEQNFGRVPIRIETN"
     gene            complement(13775..14515)
                     /locus_tag="VQU19_000426"
     CDS             complement(13775..14515)
                     /locus_tag="VQU19_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET2479734.1"
                     /translation="MATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKERKKLLELA
                     CGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGKYD
                     FVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHENA
                     EDFAMLWDTYEDEVPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQAG
                     FKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            complement(14835..15188)
                     /gene="rsfS"
                     /locus_tag="VQU19_000427"
     CDS             complement(14835..15188)
                     /gene="rsfS"
                     /locus_tag="VQU19_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HET2479735.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            complement(15201..15701)
                     /locus_tag="VQU19_000428"
     CDS             complement(15201..15701)
                     /locus_tag="VQU19_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HET2479736.1"
                     /translation="MKTAFIIIDVQNILVETGFQTKSLLGKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEERFADVL
                     DYKHIF"
     gene            complement(15702..16295)
                     /gene="yqeK"
                     /locus_tag="VQU19_000429"
     CDS             complement(15702..16295)
                     /gene="yqeK"
                     /locus_tag="VQU19_000429"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HET2479737.1"
                     /translation="MSYQDYINCSREALLEKMAEFLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSNQEFLALIDRYQLDPDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEVHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIANLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKEN"
     gene            complement(16295..16924)
                     /locus_tag="VQU19_000430"
     CDS             complement(16295..16924)
                     /locus_tag="VQU19_000430"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HET2479738.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEKNPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKV
                     GTSYPVIWVDVPLMDISSSMVRDFLAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            complement(16976..17287)
                     /gene="yhbY"
                     /locus_tag="VQU19_000431"
     CDS             complement(16976..17287)
                     /gene="yhbY"
                     /locus_tag="VQU19_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HET2479739.1"
                     /translation="MSLASKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            complement(17501..18607)
                     /gene="yqeH"
                     /locus_tag="VQU19_000432"
     CDS             complement(17501..18607)
                     /gene="yqeH"
                     /locus_tag="VQU19_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HET2479740.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGTAKVAVWAPEGVAVATRKAII"
     gene            complement(18610..19200)
                     /locus_tag="VQU19_000433"
     CDS             complement(18610..19200)
                     /locus_tag="VQU19_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HET2479741.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            complement(19152..20060)
                     /locus_tag="VQU19_000434"
     CDS             complement(19152..20060)
                     /locus_tag="VQU19_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HET2479742.1"
                     /translation="MVLEKQLGHGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLESHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            complement(20117..20677)
                     /locus_tag="VQU19_000435"
     CDS             complement(20117..20677)
                     /locus_tag="VQU19_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HET2479743.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            20816..22025
                     /gene="sstT"
                     /locus_tag="VQU19_000436"
                     /pseudo
     CDS             20816..22025
                     /gene="sstT"
                     /locus_tag="VQU19_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            22093..23046
                     /locus_tag="VQU19_000437"
     CDS             22093..23046
                     /locus_tag="VQU19_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HET2479744.1"
                     /translation="MSISQRTTKLILATCLACLFAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            complement(23282..23362)
                     /locus_tag="VQU19_000438"
                     /pseudo
     CDS             complement(23282..23362)
                     /locus_tag="VQU19_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(23417..23641)
                     /locus_tag="VQU19_000439"
     CDS             complement(23417..23641)
                     /locus_tag="VQU19_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory secretory protein Asp5"
                     /protein_id="HET2479745.1"
                     /translation="MIEMLIVLAIILSLALIVLVTIQPRQNQLFSMDATSNIGKPSYW
                     QSNTLVKVLTLLVSLALFVLLLTFMVITYK"
     gene            complement(23646..23825)
                     /gene="asp4"
                     /locus_tag="VQU19_000440"
     CDS             complement(23646..23825)
                     /gene="asp4"
                     /locus_tag="VQU19_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory secretory system protein Asp4"
                     /protein_id="HET2479746.1"
                     /translation="MSEEDLFYKDVEGRMEELKQKPIKKEKETRGEKISKTFSLLLGL
                     MILIGLLFTLLGILR"
     gene            complement(23827..25164)
                     /gene="gtfB"
                     /locus_tag="VQU19_000441"
     CDS             complement(23827..25164)
                     /gene="gtfB"
                     /locus_tag="VQU19_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system glycosylation chaperone
                     GtfB"
                     /protein_id="HET2479747.1"
                     /translation="MIELYDSYSQESRDLHESLVATGLSQLGVVIDADGFLPDGLLSP
                     FTYYLGYEDGKPLYFNQVPVSDFWEILGDNQSACIEDVTQERAVIHYVDGMQARLVKQ
                     VDWKDLEGRVRQVDHYNRFGACFAKTTYSADSEPIMTVYQDVNGQQVLLENHVTGDIL
                     LTLPGQSMRYFANKVEFITFFLQDLEIDTSQLIFNTLATPFLVSFHHPDKSGSDVLVW
                     QEPLYDAIPGNMQLILESDNVRTKKIIIPNKATYERALELTDEKYHDQFVHLGYHYQF
                     KRDNFLRRDALILTNSDQIEQVEAIVEALPDVTFRIAAVTEMSSKLLDMLRYPNVVLY
                     QNASPQKIQELYQLSDIYLDINHSNELLQAVRQAFEHNLLILGFNQTVHNRLYIAPEH
                     LFESSEVAALVETIKLALSDVDQMRQALGKQGQHANYVDLVRYQEIMQTVLGG"
     gene            complement(25157..26668)
                     /gene="gtfA"
                     /locus_tag="VQU19_000442"
     CDS             complement(25157..26668)
                     /gene="gtfA"
                     /locus_tag="VQU19_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system glycosyltransferase GtfA"
                     /protein_id="HET2479748.1"
                     /translation="MTIYNINLGIGWASSGVEYAQAYRAGVFRKLNLSSKFIFTDMIL
                     ADNIQHLTANIGFDDNQVIWLYNHFTDIKIAPTSVTVDDVLAYFGGEESHREKNGKVL
                     RVFFFDQDKFVTCYLVDENKDLVQHAEYVFKGNLIRKDYFSYTRYCSEYFAPKDNVAV
                     LYQRTFYNEDGTPVYDILMNQGKEEVYHFKDKIFYGKQAFVRAFMKSLNLNKSDLVIL
                     DRETGIGQVVFEEAQTAHLAVVVHAEHYSENATNEDYILWNNYYDYQFTNADKVDFFI
                     VSTDRQNEVLQEQFAKYTQHQPKIVTIPVGSIDSLTDSSQGRKPFSLITASRLAKEKH
                     IDWLVKAVIEAHKELPELTFDIYGSGGEDSLLREIIANHQAEDYIQLKGHAELSQIYS
                     QYEVYLTASTSEGFGLTLMEAIGSGLPLIGFDVPYGNQTFIEDGQNGYLIPSSSDHVE
                     DQIKQAYAAKICQLYQENRLEAMRAYSYQIAEGFLTKEILEKWKKTVEEVLHD"
     gene            complement(26680..29052)
                     /gene="secA2"
                     /locus_tag="VQU19_000443"
     CDS             complement(26680..29052)
                     /gene="secA2"
                     /locus_tag="VQU19_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system translocase SecA2"
                     /protein_id="HET2479749.1"
                     /translation="MFRRLGQDFQLRKVKKILKQINALKGKMSSLSDQELVAKTVEFR
                     QRLSEGESLDDILVEAFAVVREADKRILGMFPYDVQVMGAIVMHYGNVAEMNTGEGKT
                     LTATMPVYLNAFSGEGVMVVTPNEYLSKRDAEEMGQVYRFLGLTIGVPFTEDPKKEMK
                     AEEKKLIYASDIIYTTNSSLGFDYLNDNLASNEEGKFLRPFNYVIIDEIDDILLDSAQ
                     TPLIIAGSPRVQSNYYAIIDTLVTTLVEGEDYIFKEEKEEVWLTTKGAKSAENFLGID
                     NLYKEEHASFARHLVYAIRAHKLFTKDKDYIIRGNEMVLVDKGTGRLMEMTKLQGGLH
                     QAIEAKEHVKLSPETRAMASITYQSLFKMFNKISGMTGTGKVAEKEFIETYNMSVVRI
                     PTNRPRQRIDYPDNLYITLPEKVYASLEYIKQYHAKGNPLLVFVGSVEMSQLYSSLLF
                     REGIAHNVLNANNAAREAQIISESGQMGAVTVATSMAGRGTDIKLGKGVAELGGLIVI
                     GTERMESQRIDLQIRGRSGRQGDPGMSKFFVSLEDDVIKKFGPSWVHKKYKDYQVQDM
                     TQPEVLKGRKYRKLVEKAQHASDSAGRSARRQTLEYAESMNIQRDIVYKERNRLIDGS
                     RDLEDVVVDIIERYTEEVAADHYASRELLFHFIVTNISFHVKEVPDYIDVTDKTAVRS
                     FMKQVIDKELSEKKELLNQHDLYEQFLRLSLLKAIDDNWVEQVDYLQQLSMAIGGQSA
                     SQKNPIVEYYQEAYAGFEAMKEQIRADMVRNLLMGLVEVTPKGEIVTHFP"
     gene            complement(29045..29485)
                     /gene="asp3"
                     /locus_tag="VQU19_000444"
     CDS             complement(29045..29485)
                     /gene="asp3"
                     /locus_tag="VQU19_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp3"
                     /protein_id="HET2479750.1"
                     /translation="MIITQRQSIYWGEVGGTYMYGTTVSYYLDKSVRLYNPLLPSGEI
                     LKTWFSSVNYQAARTQPQLPLLKRKQEYQLSLVFDCQPENGVYTKITFFDRYGDILEK
                     KVEKAKDFIFTYPEDSYTYQVSLLSAGFESLTFYHFSIKEIRSV"
     gene            complement(29482..31017)
                     /gene="asp2"
                     /locus_tag="VQU19_000445"
     CDS             complement(29482..31017)
                     /gene="asp2"
                     /locus_tag="VQU19_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp2"
                     /protein_id="HET2479751.1"
                     /translation="MSKELNILQIGLANWENHYDIPENMSWYYFYPNSSKTLREIIEK
                     EDINRFHAVLIEDGQYSRDLFSYVKYFEPYTLFYNQNLQINDREVVDFLKKRCAQAID
                     FLSPQQLINDLSKSLFGGGYGDKLFPPTIQVNPNFTGAISYQGLDYVSLEGEFGQDFA
                     QLAYWAYNIMVQKTLPIELWLEYEKEGNCDFRLVIRKMWSGSVDDFFEEVIVSEKDLE
                     QALFMDSRDGDYFLSISVEARGRGTIKLGNLHQRWSRKQFGKFVLGGNILHDSKRDEI
                     NYFFHPGDFKPPLTVYFAGYRPAEGFEGYFMMKTLGCPFILFSDPRLEGGAFYLGTDE
                     LEGKVKDTITHYLDYLGFDHKDLILSGLSMGTFPALYYGASFEPHAIIVGKPLANLGT
                     IASRGRLDAPGVSNLAFDCLIHHTGGTSSQDMTELDQRFWKIFKQANFSKTTFGLSYM
                     KDEEMDPQAYEQLVSYLCNTGAKILSKGTAGRHNDDTDTNISWFLHFYRMVLETGFGR
                     EKR"
     gene            complement(31001..32581)
                     /gene="asp1"
                     /locus_tag="VQU19_000446"
     CDS             complement(31001..32581)
                     /gene="asp1"
                     /locus_tag="VQU19_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp1"
                     /protein_id="HET2479752.1"
                     /translation="MYYFIPAWYGSERTWHADITPWYFSHFRLEFDDTFHQIRLFQEQ
                     DIDSRLLVLAYQPHLRYFLYRHGVLETDTYSVFDVMQDFHNLHTQVLSIRDIEWDDDC
                     EFIYSPFTIIVQKNGKKFAKVEHGVEGFISDIQYFEPNGQIHMHHIMDDRGFISSIIF
                     FEDGQAAYQEYLNPKGVWQFRERLKEGGQVEVNPILGYRFKMLTYQNMGDLVAEFFEN
                     YLQTYVKDQDIFMLPSHSHHDQLVLDRLPSTNPKLLSLFIGRNPQDTFRDLDVTFEKS
                     DLILVDREDSLRLLQELYPERMHQCYHLSSFDTRLRLGRSQTKKESIIYFQLDFEQGI
                     DNQALLQVLSFVAENKDTEVIFGAFAASQEQMNEVEGIVESFIQENIQSENLGKAIDY
                     GDAENPLEENQHQDLRLQFVNLNDELDLIKTLEFVRLIVDLNRHPHLYTQIAGISAGI
                     PQINLVETVYVEHLKNGYLLTDVTEFSKAAHYYTDRLKEWNESLIYSIDKIKEHTGQQ
                     FLGKLEKWIEEVKNVKGT"
     gene            complement(32591..33808)
                     /gene="secY2"
                     /locus_tag="VQU19_000447"
     CDS             complement(32591..33808)
                     /gene="secY2"
                     /locus_tag="VQU19_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein translocase subunit
                     SecY2"
                     /protein_id="HET2479753.1"
                     /translation="MTKIYSSIAVKKGLFTLFLLFIYVLGSRITLPFVDLNTKDFLGG
                     STAYLAFSAALTGGNLRSLSIFSVGLSPWMSAMILWQMFSFSKRLGLTSTSIEIQDRR
                     KMYLTLMIAVIQSLAVSLRLPVQSSYSAILVVLMNTILLIAGTFFLVWLSDLNASMGI
                     GGSIVILLSSMVLNIPQDVLETFQTVHIPTGIIVLLALLTLVFSYLLALMYRARYLVP
                     VNKIGLHNRFKRYFYLEIMLNPAGGMPYMYVMSFLSVPAYLFILLGFIFPNHSGLAAL
                     SKEFMIGKPLWVYVYISVLFLFSIIFAFVTMNGEEIADRMKKSGEYIYGIYPGADTSR
                     FINRLVLRFSVIGGLFNVVMAGGPMLFVLFDEKLLRLAMIPGLFMMFGGMIFTIRDEV
                     KALRLNETYKPLI"
     gene            complement(33865..34542)
                     /locus_tag="VQU19_000448"
     CDS             complement(33865..34542)
                     /locus_tag="VQU19_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HET2479754.1"
                     /translation="MGISVAKGEYITIVDSDDIVKENMIETLYQQVQEKDADVVIGNY
                     YNYDESDGNFYFYVTGQDFCVEELAIQEIMNRQAGDWKFNSSAFILPTFKLIKKELFN
                     EVHFSNGRRFDDEATMHRFYLLASKIVFINDNLYLYRRRSGSIMRTEFDLSWARDIVE
                     VFSKKISDCVLAGLDVSVLRIRFVNLLKDYKQTLEYHQLTDTEEYKDICFRLKLFFDA
                     EQRNGKS"
     gene            complement(34527..34769)
                     /locus_tag="VQU19_000449"
     CDS             complement(34527..34769)
                     /locus_tag="VQU19_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET2479755.1"
                     /translation="MSELISVVVPIYNTGKYLVECVEHILKQTYQNIEIILVDDGSTD
                     NSGEICDAFMMQDNRVRVLHQENKGGQHKLKIWGLV"
     gene            complement(34769..35965)
                     /locus_tag="VQU19_000450"
     CDS             complement(34769..35965)
                     /locus_tag="VQU19_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HET2479756.1"
                     /translation="MRKSIVLAADNAYLIPLETTIKSVLYHNRDVDFYILNSDIAPEW
                     FKLLGRKMEVVNSTIRSVHIDKELFESYKTGPHINYASYFRFFATEVVESDRVLYLDS
                     DIIVTGELATLFEIDLKGYSIGAVDDVYAYEGRKSGFNAGMLLMDVAKWKEHSIVNSL
                     LELAAEQNQVVHLGDQSILNIYFEDNWLALDKTYNYMVGVDIYHLAQECERLDDNPPT
                     IVHYASHDKPWNTYSISRLRELWWVYRDLDWSEIAFQRSDLNYFERSNQSKKQVMLVT
                     WSADIKHLEYLVQRLPDWHFHLAAPCDCSEELTSLSQYTNVTVYQNVLHSRIDWLLDD
                     SIVYLDINTGGEVFNVVTRAQESGKKIFAFDITRKSMDDGLYDGIFSVERPDDLVDRM
                     KNIEIE"
     gene            complement(35974..37194)
                     /locus_tag="VQU19_000451"
     CDS             complement(35974..37194)
                     /locus_tag="VQU19_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 8"
                     /protein_id="HET2479757.1"
                     /translation="MRNTKRAVAFAGDYAYIRQIETAMKSLCRHNSHLKIYLLNQDIP
                     QEWFSQIRIYLQEMGGDLIDCKLIGSQFQMNWSNKLPHINHMTFARYFIPDFVTEDKV
                     LYLDSDLIVTGDLTDLFELDLGENYLAAARSCFGAGVGFNAGVLLINNKKWGSETIRQ
                     KLIDLTEKEHENVEEGDQSILNMLFKDQYSSLEDQYNFQIGYDYGAAAFKHQFIFDIP
                     LEPLPLILHYISQDKPWNQFSVGRLREVWWEYSLMDWSVILNEWFSKSVKYPSKSQIF
                     KLQCVNLTNSWCVEKIDYLAEQLPEVHFHIVAYTNMANELLALTRFPNVTVYPNSLPM
                     LLEQIVIASDLYLDLNHDRKLEDAYEFVLKYKKPMIAFDNTCSENLSEISYEGIYPSS
                     IPKKMVAAIRSYMR"
     gene            complement(37225..39669)
                     /locus_tag="VQU19_000452"
     CDS             complement(37225..39669)
                     /locus_tag="VQU19_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_1767 family glycosyltransferase"
                     /protein_id="HET2479758.1"
                     /translation="MIKTIVLAGDRNYIRQLETTIKSILYHNRDVKIYILNQDIMPDW
                     FRKPRKIARMLGSEIIDVKLPEQTVFQDWEKQDHISSITYTRYFIADYIQEDKVLYLD
                     SDLIVNTSLEKLFSICLEEKSLAAVKDTDGITFNAGVLLINNKKWRQEKLKERLIEQS
                     IVTMKEVEEGRFEHFNGDQTIFNQVLQDDWLELDKEFNLQVGHDVTAFYNKWENYFNE
                     LVPPSIIHFVSYRKPWTTLIANRYRDLWWEFHDLEWTKILQHHIGEFELTSSLDKEFS
                     CLTLTNSQDLEGIEELVTALPDVVFHIAAWTDMGDKLIKLAVYDNVRLHPQIVPPVLD
                     KLKKSTNLYLDINHGSADENFLKSLQEQEKTLLAFQSTQHGELGQIVFENGKVSFMID
                     TIKDFKKNGHLTCFRQLPSLTCLTFTASQDIEQLDYLAGQLPNVVFQVAAWTAMGPKL
                     YDLSNRYPNIQLYPAISRDKLDELKEKMDAYLDINLLTSTSDIVAEMAHLSKPILAFY
                     KSQNGNNGQRLYSSEHPERMLADLQKLITKDMLEKPLDIIQVKGIDETLDYIIEHNSS
                     LVRFGDGEINMLAGHSIPYQDYDEELVSIMRDIIGQESREDLVVCLPDAFTDRFRFTS
                     WAIPFWKDHMDHYMDFYRELCSDSWYGSTFVSRPYIDFEDKSQAKAQFEKLKSIWENR
                     DLLIVEGATSRSGVGNDLFDEANSIKRIICPSHSAFSRVHEIEQEIEKYAGGRLILCM
                     LGPTAKVLSYNLCQMGYQVLDVGHIDSEYEWMKMGAKTKVKFSHKHTAEYNFDQDIEF
                     IDDETYNSQIVARILN"
     gene            complement(39679..40689)
                     /locus_tag="VQU19_000453"
     CDS             complement(39679..40689)
                     /locus_tag="VQU19_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HET2479759.1"
                     /translation="MKLHLTNLYGMAGDSTVILAQNAVQKIASQLGFREVGIYFYNIA
                     SDSPSEMNKRLDGIMASISIGDILVFQSPTWNGFEFDRLLFDKLKDMQVKIICFIHDV
                     VPLMFDSNYYLMKDYMYMYNLSDVLIVPSERMKTRLMEEGLTTKKILVQGMWDHPHDL
                     SLYTPAFKKELFFAGSLERFPDLQNWSQDTPLRVFSNKGEASSSARNLSIEGWKKDEE
                     LLLELSKGGFGLVWGTYQNDGESNQYYTLNISHKVSTYLTAGIPVIVPSSLSTAKFIV
                     DQGLGFVANSLEEVHAIVDKMNLQEYQEMTNRIKTFSYLLKEGYFTKKLLVDAIYHLG
                     VE"
     gene            complement(40718..41593)
                     /locus_tag="VQU19_000454"
     CDS             complement(40718..41593)
                     /locus_tag="VQU19_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000426741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET2479760.1"
                     /translation="MENELISIVVPIYNVENYLRQCLDSIQKQTYPNFECIMVNDGSP
                     DHSSKICEEFVEKDSRFKYFEKANGGLSSARNLGIECSGGAYITFVDSDDWLEHDALD
                     RLYGALKKENADISIGRYNSYDETRYVYMTYVTDPDDSLEVIEGKAIMDREGVEEVRN
                     GNWTVAVLKLFKRELLQDLPFPIGKIAEDTYWTWKVLLRASRIVYLNRCVYWYRVGLS
                     DTLSNTWSEKRMYDEIGAREEKIAILASSDYDLTNHILIYKNRLQRVIAKLEEQNMQF
                     TEIYRRMMEKLSLLP"
     gene            complement(41633..42511)
                     /locus_tag="VQU19_000455"
     CDS             complement(41633..42511)
                     /locus_tag="VQU19_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exopolysaccharide biosynthesis protein"
                     /protein_id="HET2479761.1"
                     /translation="MKKNHLVGDALILTVSDQIEELDYLLESLPNICFYIAAPVQFSE
                     KIRSLETNYNVRLRTITNEEQLNFLVDTCDFLLDINHFQEVDAIVSKFVQAGKSVFAF
                     DNTVHGNQGQEVFLSSTPDKLVSRVRDYLNEVRVGTNHQEKIIQDGTWNVFKIDDKAH
                     FIVGANVICRNFENFHVSSGKLILHDGVFINNSCSFNCMERIEIGAGTMMGEGVRFYD
                     HDHIYTAEKIEKWQWTTAPIRVGRDCWIGSNVTILKGVTIGDNTIIGAGCLIRNDIPS
                     NSVVYNNGNLVVKRRD"
     gene            complement(42508..44593)
                     /locus_tag="VQU19_000456"
                     /pseudo
     CDS             complement(42508..44593)
                     /locus_tag="VQU19_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000341103.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
     gene            complement(44654..>45847)
                     /locus_tag="VQU19_000457"
     CDS             complement(44654..>45847)
                     /locus_tag="VQU19_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET2479762.1"
                     /translation="STSASESASTSASASASTSASASASTSASASASTSASESASTSA
                     STSASASASTSASASASTSASTSTSTSASTSASTSASTSASTSASTSASESASTSAST
                     SASTSASASASISASESASTSASASASTSASASASTSASESASTSASASASTSTSASE
                     SASTSASASASTSASASASTSASASASTSASESASTSTSASESASTSASASASTSASA
                     SASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASA
                     STSASASASTSASASASTSASASASTSASASASTSASESASTSASESASTSASASAST
                     SVSNSANHSNSQVGNASGSTGKSQKELPNTGTESSIGSVLLGVLAAVTGIGLVAKRRK
                     RDEEE"
BASE COUNT        13356 a        10302 c         8230 g        13959 t
ORIGIN      
        1 cgattgattt ttacttccgt cgcatcaatc attaccgtgt cttcagaact gagaggagtt
       61 cttgaaatcg taacaccacc tttgaacaag agttacttca acccattggc tccgacggag
      121 taagttgctt tcgtggatac caaaatcagc cgcaatttct tcataagtgc ggtattctcg
      181 cacatataga aagcgttgtt aatttattta tctcattttt cagaaaattc ttttatttct
      241 gtaaagtcta cgatactcga tgtgttttta tataatgata cagtctgaga atcactgttc
      301 cgctagccat tccaatagag attaccaaag ccaacatgac aaccaaggtc gcacttgcca
      361 gtgctttatt atagtcccct gtcacaaaaa aggcagttgt tcggtaggag agataacctg
      421 gaaccagcgg tgccaaaatg gccaagataa agaccacagc aggtgtctta taaagaatac
      481 ttaaaatctg gctgacacaa gaaccaataa tggctgcaat gaaggtagct acaatgacat
      541 tggtcggttc cttgagcaag agatagatta gccagacagt catgcccaaa atccctccag
      601 gtaagagcat agaccgttgc acattgagta cgattaaaaa agtgataatg gcaagaaaac
      661 ttgctactgc ttgtaataaa aaggttgtta gtgtcatatt agttcatcaa taccaaggcg
      721 acagaagttc ctgcccctaa agcgagggta atgagcaggg attcaaacat cttactcata
      781 ccagagttta tgtggttggt cataatatca cggaccgcat tggtcaaggc aatacctggt
      841 acaaacggca tgaccgcacc agctataatc aaatctgccg ttgaaggaaa acctgtgtag
      901 cgagcccaaa actgggcaat tatcccaaag acaaaggctc cagcaaaggc tgtcacaaag
      961 ggaattcgga taaatttttc cacatagagg gaaaaggcaa aaccaaataa ggtcgccact
     1021 cctgccccaa gtgcgtcgta gatatttccg ctaaacataa ctgaaaagaa aggagcacta
     1081 aaggtcgcag ccagagttac ctgcaactta gtatagggaa ggggttgagc ttgcaaggcc
     1141 gtcaattgct taaaggctgt ttctaagtca atctgccccc caactagctg acgagaaatc
     1201 tggttcacat cgcagacttt ttcgatgtta taagaagagg aggtcacgcg cttcatgcgc
     1261 gaaatattgg tattttcaat agagaaaaag atagcggcag gcatggcaag gacattgcaa
     1321 tccacaatcc cctgcgaatg cgcgattcga atcatggtat cttctacacg atggatttct
     1381 gagccacttt taaggagaat agtccccgct agcataatca catcaatgac ggcatttaat
     1441 tcttttgatt cttccatgct ttcctccttt tatcaactcc ctctattcta tcacaaatcc
     1501 ggactcaaaa aaaatctttg ccatgaaatc atgacaaaga ttgattactc attttgatta
     1561 tccatctgct tttaaggagt agctgaagtt gttttaggtt tgtagattga aatcttgact
     1621 ctagtcttat tgaggtctac cttttcacct gctctaggac tttgttcaac aaccatgcct
     1681 tctacactac ctgcaggcgc tgtcgtcact tctacaactt ctatattagc ttccttaatc
     1741 ccaacaattt gaatcaaatt gttcttagta aactccaagc tggaaccaat gtaactcggc
     1801 atggcaacac ttgtaacttt tttagctact gtcaagacaa tttgagtagg tttactcaca
     1861 tcataagtcg ttccggcacc tggactttgt ttcataatcg ttcctggttc gctttcgctg
     1921 gactcttctt cctctatctt aatcaaattc tcaggaacct tcttctgctt gagttctgag
     1981 attacttctg tagagttccg tccaatatag ttccctaatt gaatcgtcgt agctttttta
     2041 gctactgtca aaacaatttg agttgccttg ctcaagtcat aggtcgtacc ttctggtaga
     2101 ctttgcttca ggaccgttcc agcctcactc tcattcgact cttcttcctc aattttaatc
     2161 aaattatctg gaactttttt ctcttttaat tccgcgataa catcagaaga tttccggccg
     2221 acataattac taatttggaa ggattgtttg cctgatgaga caaccagatt gattttcgtt
     2281 ccttcttttc gaccagttcc agcgccagga tctgtacgga taatccgccc ttcttccacc
     2341 ttttcactag cctctgtctt ctcctcacca atctcaaaat tggctttttt gagcgttgcc
     2401 ttggcctctg caactgtctg acctgccaca tctggaatgg caatggttgc aggagttctg
     2461 gatagtatcc aaataagaga agctgccacc aatacaaggc tggccaacaa aatcaggtaa
     2521 cgcatcttaa atctatgttt tttcggtgct tgtggttggt aagtttcctc tgtcacagcc
     2581 tggcttgggt ttttgattga tttgtgttct gtctgcgctt gaaccttagg aatagatgtc
     2641 aaggtactct gagaaacctt cggcaaggtc ttggtatctg ccttgctcgt ttcatcaaag
     2701 attaacttac tttcatttct acgattgtag gacaagctac tagacaagtc cacatacatc
     2761 tctgaaaccg agcggtagcg attggtcaac tttttagcag ttgccttgat aataacattt
     2821 tctaaagcct gaggtacaga tggattttct gcaataacgg acggcagggg tttctggaaa
     2881 tgctggaggg caatggtcac cgcgctatcc ccgtcataag ggatatggcc tgtcaacatc
     2941 tcatagaaaa taatccccat ggcatagata tcactctgca cagtcgcctt cgaaccacgc
     3001 gcctgctctg gtgacaagta atgaactgag cccaacatcg agttagtctg ggtcagactt
     3061 gtctctgcaa aggctacagc aatcccaaag tctgtgacct tggcagtccc atctggtgtc
     3121 aaaaggatat tttgaggttt caagtccctg tgaacaattc ctcgagtatg ggccaagcgc
     3181 atagccaaga gaatttgtcc catgatacgg actgcttctt cattagaaag aggataatgt
     3241 tccttgatat agcgtttgag gtccagtcca gccacatact ccatagctag gtactgttga
     3301 ccgtcttcct cgccaatatc tgttatccga acgatatgag gatggtctag atctgccata
     3361 gctctcgctt cacgctgaaa acgagctaca gctatcgggt ccgtctggta gttggtcctc
     3421 agaaccttca ctgccacttc ttccccatct aagattaagt ctttggctag gtagacatcc
     3481 gccatgcctc ctcgaccaat ctgtttgaca atccgatagc gtccggcaaa aatcttgccg
     3541 atttggatca ttctgcatcc tcctcgttca taaaaacaag ggcaaccgta atgttgtcta
     3601 aacctcctgc attgttagca aaacgaacaa gtgtctccgt tttatctgct aaaggaatat
     3661 cactggttac aatatcacga atctcactgc ctgaaatcat gttggtcaag ccgtcactat
     3721 tgagcaagag atagtcacct gactcaagga taactgtccc aaaatcaggc tgaatttcat
     3781 ctttttgccc aatagactgg gtgataatat ttttttgcgg atgagcttct gcctcttctg
     3841 gtgtcaattg accagccttg agcaattcat taaccaagga atgatcgctc gtcaactgat
     3901 ggtattcttc tccacgaatc aagccgatac gcgaatcacc aatatgagca tagatagcct
     3961 gattatcaat aatagcaagg acttccaaag tagttcccat gcctctgtaa gcttcatcct
     4021 gaccaagctg gtgaatcttt tgattttcaa tttctaggta atgggcgaac cattcacgca
     4081 cttcattgac tgtatcgatc tgggtatcaa cccaagctac acccaggtct gtgaccgcca
     4141 tttcactagc gatattccct gcacgatgac ctcccatccc atcagctaaa ataatcatgg
     4201 tacgtccagc tctattgaca tagtggttga catagtcttg gttatttgtt cgtttctgac
     4261 caacatctgt taataatgaa atttccatgt gtcagttcct tcctaatccg atatcttgcg
     4321 aaattgactg atgaagaatc catcacttcc atacaattca ggtgtaatga ggatacagcc
     4381 gtctttcatg atatccttac attcatgttc tagttttacc tgctcgaact cgggatgact
     4441 ctctaaaaag gccttaacga cttgaaaatt ctcctctgag acgatagtgc aggtgctata
     4501 agttattata ccacctttgc ctagtatttg acaaacacta cctaatattt ctaactgaat
     4561 ttcctgcaag gacgcgaaat ctgccgtttc tttattgtat ttgatatctg gttttcggcg
     4621 caaaagaccg attcctgaac aaggagcatc caccaaaatc ttatcaaagg aatcctggtc
     4681 aaaaaactca tgcacctttc tggcatccaa tttttgagtt tgaacccgat cttcaactcc
     4741 cagacgttgg gcattttctt gaattaaatc caacttgtgg tcgtacaagt ccagagcagt
     4801 aacctgacct gtcgtaagat aagaggctat atgggctgtt ttcccacctg gagccgcaca
     4861 ggcatcaagc actcgctcat caccttgtaa atcaagcgtc ggagcaacca actgactgga
     4921 ctcgtcttgg atggtaatgg ctccatccgc aaacaaatta tgccctgcaa aatgcccctg
     4981 ctccttaacc agaccagtgg ttgctaaaag ggaattattc gcctccaaca aggcttggat
     5041 ttcctctttt cgacttaggt ctgttacacg aatactggct ttgtttcgca ctaacaggct
     5101 ttcaaagatg gcttttgctc tctcctctcc gtattcttcc ttgagtttgg caactagcca
     5161 aactgggaga gaataggcaa tggagtcacg cttgtttttt cgcttgatgc tagcaatatc
     5221 tggccagcct tcacgcaaga tacggcgaag gacagcgttg accaattttt cactgccttt
     5281 tttacggagt ttggccaatt ccactgcttc attgaccaca gcatgatctg gaatcttgtc
     5341 caaatagcgg agttggtagg cactcatgag aagaaggaca tagagccagc tgtctaactg
     5401 gtctctgtct tcgataaagt gggataggta ccattccaga gtcagtttac gggctaccgt
     5461 tccatagact agctcggtca ctaagccctt gtctgctgca gagagctgac tccccttgag
     5521 gtgtttattt aaggcaatat ttgaatatgc ttgattcaca aaaacatcct ctagcactgc
     5581 tagagctaaa cttctagccg tttctacttt agtcaccaaa tcgttctcct acagtcaatg
     5641 tacgtccaac tccattgagg aaggaagcaa tgtccatctt aggcttacca gctggctgca
     5701 cttgtttgag ggatagagcc ccttcagccg ttgcgacaat caattctttc ttgccgatag
     5761 agagaatctc acctggattt ccctgacctt ctactggtag ggcttcataa atcttaaagc
     5821 ggtcgccctt aaggaaagta tgggcaacag gccaggggtt cattccacga atttggttaa
     5881 agagttgacg attggttttg ttccagtcca gtttttcttc ctctggcttt atatttggag
     5941 agaaggtaac ctgactcgta tcctgcggtt caggtttgat atcaccagca atataggcag
     6001 gcagagtgtc caaaagcaaa tcacgaccaa ctagcgccaa tttttcaaac aaggtgccaa
     6061 cattgtcctc atctgtgatc ggaatgctgc gacgagaaat catatctcct gcatccattt
     6121 ccttaaccat ttccatgatg gtcacaccag cttcctcatc cccttgaatc aaggcataat
     6181 ggataggcgc accaccacgg tgtctaggaa ggagggaggc atgaacgttg acagcaaagt
     6241 ccatgctatc aaggagtttg cttgggagaa actgcccaaa agcagcagtc acaattccat
     6301 ctgctcctag cttcataagt tcttccatct ctggacttcc agataatttt tcaggttggt
     6361 agatagatag tcctgcttcc ttggcagcct gcttgactgg ggtttcttgg ataacttttt
     6421 tacgaccaac agcacggtct ggctgggtca caacggctag aatttcgtaa cggtcatctg
     6481 tcaaaagtcc ttttaagact gttgctgaaa agtcgggggt ccccataaag attagttttg
     6541 tcatatcttc tccttcttat aaaaattgct gcggctcatg gtcaatgctg agacggagct
     6601 cactattttc ccgttcttga gtcaaggcca agacctggtt gagggtcggc cccagctcat
     6661 cttctaaacg gtatttaatt aaaatctggt aatgatagag gttgtgggta cgggcaatcg
     6721 gttttggcgt tggccccaga atgggactgg tctctgacaa gcctgaccgc aaaatgttca
     6781 tgacttcata ggcacgtttg aaaacctctt cttctttctt gtgagaaagg gtaataccaa
     6841 tcgtgaaata gtaaggtgga tagccgagtt gtcgtctgat tcccatttca taggcataaa
     6901 agccttcgta atcttgatcc ttggcaaatc gaatagcata gtgctgcgaa ttgtaggact
     6961 gtatcaagac ttgacctgct ttttcagccc gacctgctcg acctgccacc tgagtcaaga
     7021 gctggaaggt tctctcagaa gaacggaaat caggcagatt caaggccgta tccgcattta
     7081 gaactccgac tagggtaaca ttgggaaaat ccaaaccctt tgcaatcatc tgagtaccaa
     7141 gtaaaatatc cgcttcccct cgcccaaact ggtcaagcaa ggcttggtga ctgcctttct
     7201 ttcgagtcgt atccacatcc atcctcaaaa tgcgagcttg gggaaagagt tctgctagct
     7261 catcataagc cttctgagtt cccgtcccat agtaacgaat actgcggctc ttacagttag
     7321 gacagacctg aggaatatcc ttcgagaaac cacaataatg gcagttcata gtcttggtat
     7381 ccatatgcaa ggtcagagaa atatcgcagt tgggacaagt atccaccgtc ccacactccc
     7441 gacacatgac aaagctagaa taaccacggc gattgagcat gagaaccacc tgctcttttt
     7501 taaccagacg gtcttggata gcctctagca aaggaggcgt aaagtttgac gtctcatttt
     7561 gtccgatata gtctcgaaag tcaatcactt gaacctcagg gattgtagcc aaaggattgg
     7621 cacgttgggt tagacgtaag tgttgataga cgcctttgcc agcacgtgcc cggctctcta
     7681 agctcggcgt tgcagatcca agtaccagag ttgcttgatt atactgagcc cgtaaaatag
     7741 ctacctctct ggcatggtaa cggggattgc tgtcctgctt ataagccgct tcatgctctt
     7801 catcaataat catgacaccc agatttttca gaggagcaaa gatagcagat ctggcaccaa
     7861 caacaacttg ggcatcgcca cgctccacct tgcgccattc atcatacttt tcgccattgg
     7921 ataatcctga gtgaagaatg gctaccttgt ccccaaaacg tgctataaaa cgctcggtca
     7981 tctgaggagt caaggaaatc tcaggtacca gcaaaatagc tgtcttaccc ttatccaggg
     8041 caccttggat aatctgcaag taaacctcgg tcttcccact tcctgtaatc ccttgaagta
     8101 gaaagggagg ttgagaactg ccaatagaac tcacaaccgc atcacgcgcc tgtctttgtt
     8161 ctggatttaa ctccaaaggt ctacttgctt caattccttc aaaataagca gccgagcgtt
     8221 gaacttcctt ttggactatg gtaacagtac cttgatccac aaagaagttg acttgctctc
     8281 gcgagtagga ctctaacaag ctagccaagg aagcgctctc tggatgagac agcagataat
     8341 ctctcagttc caactttttc ttggcacgtg tagaaatctc aacaccttct aattgggcat
     8401 ggtcaacctc ataccaagac tgggtcttga ccttcttttg atcgactgcc tgatattcca
     8461 gaccaagcag gccttttcta gtcaaacgca tcatttcagc ttgcttggca aggtctagtg
     8521 aagaaaaggc tagcgaatct tctgaaccaa acaggcgtac tcgttcttcc tgactcaagc
     8581 cttccagagg atagagaatc ttgtcatagc tagaattcag aaaccctgga agcatggcct
     8641 tgaggataga gattttgtag gagaagacag atttgcgtaa ctcctcagcc agccagagtt
     8701 gttctggcgt gagaacagga gaaaaatcca gcacctctgc aatatctttt aaatcttgct
     8761 ccatctcttc tccatctgat tgggacttca aaccaagaac aatcccttga atcaggcgat
     8821 tacccttacc aaaaggcaca tgaacccgca tcccaacttc cagcattccc tcaaattcct
     8881 ccggaatcct gtaactatag ggctggtccg tctgcatcaa gggcacatct acgataatct
     8941 tagctagggc catcttctca cctcctcctt gtcagtacat tcttgcaata gaaaaaataa
     9001 gattgagtcc ccccaacctt aaattttttc accatcttct ttttctttag caatttgctc
     9061 tttgattttc ttttcttctt cttctttgcg gcgtttttct tcttcgatac ggcgacgcac
     9121 tgcttcacgt tttccttctg gatctgggtg aattgtaacg tttcctgatt cgatttcttc
     9181 taaagcgcga agagttgatt tttcagactt gaaaccttga gttgctgggg cacctgcttc
     9241 caattcgtgg gcacgttttg cttccaagat tacgagtgaa tattttgaag gaaccttgtc
     9301 gagcaaggta tcaatagagg gttttaacat catttgcttg tacctatttt ctaaatttta
     9361 tcgggtagtt ggagattttg gtaacatctc ctgatagtga ccaatgacac gatccacaca
     9421 gaagtgttct gcttcaatca cacatttgac acgttcagca gctaggggca cctgatcgtt
     9481 gacaatcgca taatcatact cacgcatgag ggcaatttct tccttggcct tttcgattcg
     9541 ttgggcaatc acttctgcac tatctgttcc acgacctacc aagcgatctt gcaattcatc
     9601 caaatctggt ggtgtcagga agataaagac agcatctgga acctttttct tgacctgaag
     9661 agcaccctga acttcaattt caaggaaaac atcgattccc ttgtccaagg tttcattgac
     9721 ataggtcaga ggagttccat agtagttgcc gacatattct gcgtattcca acatctgtcc
     9781 ttgacgaatc agctcttcaa attcttcacg agtacggaag aaatagtcaa caccgtccac
     9841 ttctccagga cgttgtgcgc gtgtcgtcat cgatacagaa tattgaaatt ggttttcaga
     9901 actctcaaaa atctctcttc taaccgttcc ttttccaacc cctgaaggac cagaaaaaac
     9961 gattagtaag cctcggtctg ccattgtgtc tccttttagt caatctgtga aataacattt
    10021 ctctagaata atggcaaaaa gccagattat cctttacagt ctttctatct agtgtaacaa
    10081 aaaagcagta atttttcaac tgctctttct tatttattta gcataatcta ctgcacgaag
    10141 ctcgcgaatc acggttacct tgatatttcc tggataatcg agattgtttt caattttctt
    10201 acgaactttg tgagccaaga ttgtgacttt gtcgtccttg atttttcctg gattgaccat
    10261 gatacgaatt tcacgtcctg cttgaagggc aaagctagtt tgcactcctt caaagccgtt
    10321 agcaatttct tccaaatcat ggagacgctt gatgtagctt tcaagagact cactacgagc
    10381 acctggacgg gctgcgctca aggcatctgc tgcagcgacg ataactgcta tcacgctctc
    10441 agcttcaaca tctccgtggt gactagcaat cgtattcacc acaactgggg gttccttgta
    10501 cttacgggcc aattccatac cgatttcaac gtggctacct tcaacctcat ggtcaatggc
    10561 tttcccgata tcgtgaagga atccagcacg acgggcaaga gccgcatttt caccaagttc
    10621 gctcgccatg ataccagcca acttagcaac ctcaatcgaa tggcgcaaaa cattttgtcc
    10681 atatgaagta cggaactgca aacgtcccat aatcttcatc aagtctggat gaaggtttgg
    10741 cgcaccaatt tcataggcag cagcctcacc gtattcacga atcttattgt caatctcttg
    10801 acggtttttc tcaaccaact cttcgatacg agctggatgt atacgaccat ctttgagcaa
    10861 catttccata gtcatacggg caatctcacg acgaatcgga tcaaatcctg acaaggtcac
    10921 cacttctggt gtatcgtcga taatcacatc gacccctgtc aaactttcaa aggtacgaat
    10981 gttacgacct tcacgaccaa taatgcgtcc cttcatagta tcgtctggca gatgaactgt
    11041 tgagtttgtt gactccgcta catattcacc agcgatacgt tgcatagctt gaaccaagat
    11101 gtccttggcc attttgtcag aacgttcctt gacctcttgc tcagcttcgc gaatgcgact
    11161 ggcaatctcc ctggtcaagt tttcctctgt ctgagccaag ataatatctc gtgcttctgc
    11221 ctgagacaga gcaccaatac gctctagttc tgcttctttt tgtctttcga cttcctctaa
    11281 ttgctcttca cgcgcatcaa ggtttttcgc tctatcagaa atactttgtt ctttttgttc
    11341 aagtgtttgt tctttactcg tcaaattgtc gtccttacgg tcaaggctag tagctctctc
    11401 tgtcaaacga ctttcgattt gtttgagttc ttgacgttct gatttgaatt cagcgtccac
    11461 ttcttcacgg tattttctgg cttcttcttt ggcctccaat agtgcttctt ttttaagaga
    11521 cttgctttca cgtttggctt cattaacaag taaatccgct tcacgctcag cttgtccacg
    11581 taaattagtt gcttcttgtt cagcatttaa aagcatcaac tctgcagctt cctgagatga
    11641 tttcatctta gctgagatgc tgacatatcc aatgactaaa ccaatgatga cggcaaaaac
    11701 agcaatcgca agcgacatga tttccatgtt tttacctcat tttattgtta ttccgaatga
    11761 catacattct tttacattct accataaaaa agtgattttc acaaacctaa aatagaatat
    11821 gttttgggga atttggaaca catttaccaa aataaacttg ttgtttagaa atagtagttt
    11881 agtagagact tgagaaaaag cctactttgc agtagactta gtaatgatct ttaaaggaca
    11941 agaaagccac gctatctcca tccatcatat aaatcaagcg attttctgca tcaatacgcc
    12001 gtgaccaggc tccttggtaa tcatatttga gtggctctgg ttttcctatt cctgtaaatg
    12061 gatcgcgttg aatatccttg attaatttat tgattctttt tagtgttttt ttatcttggt
    12121 tttgtcagta gcaataatct gcccaggcat cttctgtaaa cttgagtagc attcatcact
    12181 cctcaatcac atggacctga gtgcttccag cacggacttg agccattcct cgcaaaacct
    12241 tgtctgataa ctccttattt tgggcgattc tcagggtttc ctgaatactg tcccattcgc
    12301 tctttgaaag aactacaatg tcctcatctg gatttttatt gaccaccgtc aaaggctcaa
    12361 attcatcatt taccttcttc atgtagtcct ttaaatgatt tcggaatgtt gagtaaagga
    12421 ctgcttccat aaccatacct cgttttagct cttttccact attatacacg aaaagaaaga
    12481 aattgtcagg aacttgtaca agattttctt ttctatctat ttatactcaa tgaaaatcaa
    12541 agagcaaact aggaaactag ccgcaggctg tacttgagta cggcaaggcg acgttgacgc
    12601 gatttgaatt tgattttcga agagtattat tcgtaaaaaa tctcaaaaag cctacctttc
    12661 ggtagactta gtttgtttct attctaatcg gcactcttcc aaaattttgc tctgctatac
    12721 ttggcttccc tagttggtaa atctggtctg ctttttgggt catagcatcc caaggttctt
    12781 tgccaattcg gctgactaga ttgacctgtc ctttcagaga cttgagatgt tgcctgactt
    12841 tttcagtaaa tccaaggaca tgaatggctt ctggcaagac attttctcta gcctgtacca
    12901 aaatataggt caataggcgt ctgacacgcg ccttggtgta acgtttggta gtcactaact
    12961 cgaccaattc ttccacagac tgggctgttt taatagcttc tttaatgcgc acagccattt
    13021 cttgattgac ctgatagatg gtggttaggt cgggatttga caagatttga tagcggagca
    13081 agggaaaata gtcttcccag atcaccttac tggcctgctc aaatagggca acagaaggca
    13141 taaaacgttc taagaaatct tggtccttct gatgttgacg gagggctgtc gccgaggcaa
    13201 agtccacatc tttattcaca gaatggtaac ctgccccctg acgctgaatc ggatgcagct
    13261 tgatatttcg tcctgcaacc gccttggcat aggccagagc aagaacatga ttgggggtat
    13321 tacctgaaaa atcaagacca gcaaattcct tccacatagc ttgggttttc tggggatagg
    13381 aaagggaatc aggcagattt ttcacaaatt tctccatctc agcacctttc tctgtgtata
    13441 agtcagcgat tttctggtaa tccagaactt cctctgtccc aaaaactaga ctatcaatgc
    13501 ccaagcgatc caagatatcc acagctcctt gaccaaagaa atcagctgcc tgaacactga
    13561 ctaaaaaggg caattccact accaagtctg cgccattttc cagcgccatc tgggcccttg
    13621 tccacttatc cacaatagca ggctctccac gctgcatgaa attccctgac atggcaacaa
    13681 ttttcagtcc ctctgcctga tccagcaggt atttatggcc attatgaaaa ggattgaact
    13741 ccgcgataat acctgttatg gtcatgctaa tctcctactt ctgcgccaca aaaaaccaac
    13801 gggtgctagt ttctgttggc tccttatcct caaagtctgc atagagtttg aaggacttaa
    13861 atccagcctg ttccagcaag atatcatagg tcaagatctc ataggtcctc tcctcatgta
    13921 cttcatcgtg gcgactaaag gaaccgtcag cctccttgat aaagaaagtc agctcatgca
    13981 cgatggagtg aggaacttcg tcctcatatg tatcccaaag catggcaaaa tcttccgcat
    14041 tttcatggta ggaatagcca gggaatactt catctgtctg gtaggtcgag tgcacgtcaa
    14101 agatgaaaac tccctcttca ttcagcgcat tgtacacgtc cttaaagacg tcccctactt
    14161 ccacctcatc ctgcatatag cagatagagt ccgaataaca cgtgacaaaa tcgtatttcc
    14221 ctgccttgga caaattcagc atattacctt ctataaaagc aatcttttgc ttggctgaag
    14281 ttgctctctt ctccgcaatc ttcaacatat ccgcactcaa gtcaagtcca gtcacatcaa
    14341 aaccagcctg agaaaagcgc actgattgaa ttcctgtccc acaagccaat tccaagagtt
    14401 tctttctctc cttggtctta ggcaaatgac gcagagaaaa attcgtccat ttgtcgtata
    14461 aactatcgtc catgaccgca tcatagaccg ccgcaaaggt ttcataagtc gccataaaac
    14521 atgataccaa gtccgcccgt aattcgatag aaaattagga gccttacgat ggagccgagc
    14581 tccaaggaag gctatctatt ttccgagaat tacaggacgg gttcaaatcc tttctaagat
    14641 acaaagagcc ttaaaagcaa agagtacata ggaaactttc ttccctatcg tcagatacaa
    14701 agaaagttac tttttatctc agcttttagc tcgtgttcag tttcgaaatg aaacaaacac
    14761 gaggcccttt acctttctat caatttttct aaaataagca aagaaaccca gttgactaca
    14821 actgagttca tcttctaagc aagagcttct gaaatatcta ctgaattcgc ctcatgccat
    14881 agcttctcta gattataatg ggcacgcatt tcttctgaaa agatatgcac gacaacagca
    14941 ccaaggtcca gtaagaccca gcctccagct gcatcgcctt cgacatggct acctttaaag
    15001 cctgcttgag ctactttttc acggatatta gctgcgatag cgtccaactg acggctattc
    15061 attgagctag tgatgacaaa gtagtccgtc acactagtca aatcttgtac atcaagtgcg
    15121 aggatatcct ccgcacgttt ctcatcagcc gctttcacga ctagttctag taattctttt
    15181 tcgttcattt aatcctcttt ttagaaaata tgtttgtaat ctagaacatc tgcaaagcgc
    15241 tcctcccaaa tgtcctcata aaattcatta atcgtttctg ctggaatgtc atccccatca
    15301 aaggttgtga cagcaccttc tggaacaata agctgatagc catattcaaa ggcaaccttg
    15361 acagaggtat ccacacaata ttctgtctgc ataccacata aaactaattt ttcaatcccc
    15421 tgcttatcca agtattcttt taagccagtt tctttgaaaa tactgttata cttcttctga
    15481 aagacctttt cagcaggttt tcgatttaaa agcgcagata actgccaatc ttctgatgtt
    15541 tgagcttcag agttctcaat atgttgaaca tagataattt caatattctt gcttctagcc
    15601 tggttttgta aataagaaat ttttcccaat agactttttg tctggaaccc agtttctact
    15661 aaaatattct gaacatcaat gattataaaa gccgtcttca tttagttctc tttcaaatag
    15721 tgcacaaagg cgttataggt ttcaagggtt tggggataga tggggaatcc ctgatgagct
    15781 agatactcca cggtacgagc tgtttcgtag gccaccgcct tattgagcga tagatttgca
    15841 atctcacgcg ccacatctac tccaggaaag gctcgattgt gctcgatata gtctgcgacg
    15901 tagatgacct tatctaggtc tgtcatttga ccagcaccga ctgtatggac ttcaatggct
    15961 cgcaggattt ctgaatcatg caaatccaaa tcttcctgaa ttttgtaaat tccgaccata
    16021 ccatgccaga cattattgcc ccagtttttg aggtcagggt ctagctggta acggtcaatc
    16081 aaggctagaa attcctgatt tgacaacttt ttagcatagt catgaagaag acctgctaga
    16141 cttgctttct caacatctac accaaagcgc tgagctaatt ccatagcggc acgctccaca
    16201 cctagacaat gggttagacg tttctcaggt agaaactctg ccattttttc caacaaggcc
    16261 tcacgggagc agttgatata gtcttgatag gacatcagta gagcccctcc ttctcgatgt
    16321 agtctagcac tggctgaggt aggagaaagt tgggtttccg accttgggca aggaagtccc
    16381 gcaccatgct ggacgagata tccatgagcg gtacgtccac ccagataact ggataggaag
    16441 tccctacctt gtagcgtgga cgctgaaccc ccacaaactg aaccatgtca accagttcat
    16501 caattcggta ccacttaggc agatagtcaa ccatgtcggc accgatgata aagtaataat
    16561 ccgtatctgg attcttctct gtcaaaatct tcatggtgtc gtaggtgtag gaaataccct
    16621 tgcgctccaa ctcaatggtt tcaatgacta ggccgtcaat tccctcaatt gccaactcaa
    16681 gcatcttgag acgatggtgt tcagggatgg tttccttttt atcaacgtga ggaggttggt
    16741 attcaggcat gagaagaact tgatccagtc ccaactgttg ccgtacttga tccgcaacaa
    16801 tgagatgggc attgtgaaca gggttaaaat tcccccctaa aatcccaact tgtttgcgtt
    16861 ttttctcctt gatttctggc tccaactcta ccttggtaaa gggagtcaat agttcgattg
    16921 tcataggcta gtccccttta tttctctata aaaacagtta tttggagttt cggtcttaga
    16981 tttctttgac tttcttagaa atcttgcgat tttctttctt gctagattgc ttaaacaaaa
    17041 tcaagatgcg tcctattttt tggactgtat ccacaccgat ttcttcttcc aaaatttcag
    17101 ctacttcgtg gatgttttca tctgtgtttt gtaagagagt aaccttgatt aattcacgcg
    17161 catcaagagc ttgacggacg ctggttttga tttggtcgtt gagtccattt ttcccgattt
    17221 ggatgatagg tttgagggtg tgtgcctggc tgttgaggaa ggcacgttgt tttgatgcta
    17281 atgacataat tttcttcctt gttttttgat agttatttta ggtggtgagg gacggtcgga
    17341 actaattttc caaagatttc atctttgaaa aatggatttc ctgacctcac aattgagcct
    17401 tggtctcaat tgtgcccctt gccaatctac agattggcaa tcacaccacg gcaataacta
    17461 tcgctatatg agctcacttt gttcgctcag cgattttgtt ttaaataatt gcttttcgtg
    17521 tggcgacggc gacgccttct ggtgcccaga cggcgacttt tgctgtgcct gttacacgaa
    17581 tccagcctag gcctgaaatg actaggtctg tcttatcttt aatggtaaag acatgctgga
    17641 ctagccttgg gaaatcttct ttttccttgc tatttggtgg tgtcagaaga gttcccaggt
    17701 gcttatcgta gaaagcacta gctccttcaa gcttgctacg atggagtttg agttcattat
    17761 caaagaaagc agtaaatcct tgcttttctc ctgctataaa gtcaaagcgt cccaaaccac
    17821 ctaaaaatag ggtttgctca ggattaagct gataggtctt aggcttgatt tcctttttag
    17881 gactgacata cttgaggttt ttggccgtca agtagtgagc catctggtgg cggtggataa
    17941 ttcccggcgt atcgtaaata taagatccgt cgtcaagcgg aatctctatt ttgtccaagg
    18001 ttgtccctgg gaagcgtgaa gtagtgatga cattctgatc acccgtgatt tcttggataa
    18061 tagcattgat tagagttgat tttccaacgt tggtcacacc gaccacatag acatcgcggc
    18121 ccttacggta gtgttcaatc ttatcaatga cttccttaat ggcatgttta ttttgtgctg
    18181 aagttaggac cacatcgact ggacgaagac cttcttcatg ggcacgtttc atgagccact
    18241 ggctaatctt accagactta actgacttag gaaggatatc ttttttattt cctaccaaga
    18301 ggacatcatt gcccgagacg aaacgtggta aacctgggat gacagatcca ttaaaatcaa
    18361 agatatcaat gacattgacc actaaggcat cactgtctcc cacctcgtgc aagagcttga
    18421 ggaaatcatc gttcgtcaac tggacatctg tgatttcatt gtagtggcgg agacggaaac
    18481 agcgttggca atagacttcg ccagtctcca aacctttttc aagtgccgac tggggggtaa
    18541 aaccaagacc agctttatct gtcgtctgaa tggttgctcc acaaccaata cagagaattt
    18601 cttccatagt taaattcctt ttttatatgt aatcggtccg tacttttcag tgatttttct
    18661 cataacacga cgctcacgag ttcggttaat ctgcgttttg attgagtcat gttggaccaa
    18721 gggtttgact aaaattgacc gaatccctgc acggtgggct gctcgtatat ctgtcatgag
    18781 ctggtcgcca accatgacca cttccttttt gtcatagtgg aattccttca tggcacggtc
    18841 aataccaaat gtgaagggct tcaaggccca gtaaacgtaa tcaatcccaa atttctcaac
    18901 tgctcgttga acgcgttttt tggtgttatt tgacactacg ataatgccaa tacccgcgtc
    18961 ccgaaggtca tgtagccatt gcttcatctc tggcgttcca tcagggttgt tccaagcaat
    19021 gagggtatta tccaaatcga ccaaaacagc cttgattccc tgcgcctgca ggcttgggac
    19081 tgtcagatca tagactgctt ccacagcaaa atctggtata taattttcaa tcgccattct
    19141 ggctcctttt cttaactttt tttcgcaatt ttccttagta acaaggataa aacaatccac
    19201 aaacctgcac tagccaaact gatatagagc caagcatggg gctcatctgt taaaggtaag
    19261 ggaacattca ttccgaaaaa gcctgtcacg actgccaaaa cagctagcaa gactgaaatg
    19321 atagtcaagg ttgtcaaatt gtcattcaga ttattgttta gaatattgtt gtaagaggct
    19381 gaaagctgct gtaaaatctg agagattagg tctgtcatgg ataccagctg atgagcctca
    19441 atcatggcat catcaaactg ttctctctca atctcatcaa aactacgata caaggcatga
    19501 ccttgaatat gctctaacaa aatccgattt tgtttggcag ctgccgtcag ataaaccata
    19561 ccagtctcca aatcagacag ggcaaagagg tttttcttgg tagttcgctg gcgcaagagg
    19621 tcattgacct catccctact cttgtccatc tgctcaatga caggatagta ggcattgctg
    19681 atgatttcca gactggcaaa gagaaactta taaatcgaaa gcgtgtcatg gctctccaga
    19741 taacgagtca tctgttcaat gacataggcg ttcttggtat tactaatggt aatcaggcga
    19801 cgatgctcga cgataaaggt catgggaaaa gtctcatagt aggccttgtc cttttttacg
    19861 tctaggacat tatagataaa ggtaaccgtc ccactttcac ggtggtagtc catgtgggcg
    19921 cgctcgtttc tatccagtgc gtattcaatg gtttccttgt ccaaaccgta aatttcagaa
    19981 aggtcttcta gtttattcaa ctttcctagg tctaggtcta tccaggtaca accatggccc
    20041 aactgctttt ctaaaaccat cttttctcct tattaaactc cctctattgt accacaaatt
    20101 acttaaaata acaggtctag tctgtgcgtg agaaattgct aacaactgtg atatttcggt
    20161 tagggacaaa gtgaagggct tgctcctcgc tacgaagctg tgtcgtacga attcccacac
    20221 tgacaacctt acccgataca gtaatcggtc catttgtcag aacgacctca tctcccacat
    20281 ccagttgacg ttcaaagagg atgaaaaagc cattgatgac atcagacaga aagccttggg
    20341 ctcccatacc aatcgctacc ccagcaatac cagctccagc cagcaaacta gaaactggca
    20401 aacctaaaat cgacaaaatg cagtagagta aaaagaaata tagcgtataa ttaaacacat
    20461 tttctagtaa acgtgagatg gttttttggc gtccgacatc atgacgagac atttttagag
    20521 aaggtttgac aattctctgc accatggtat gaagcatttt tttagcaata taaaatacaa
    20581 tcaaaagcag taaaagagaa atgaccttgg ttagaatatt ctcgataatg gttgtcacat
    20641 ctagcttttc aatataagcc tgaataaatt tttgcatata aaactccttt atttcattat
    20701 accatatttt catcagtctc attctccata aatattcaaa aaatagacag aaaattcttg
    20761 attttgtcta tcatttatac tataatcata atcactacac aaaaaggaga ttattatgaa
    20821 aagaatcatt catgcttgga ataaggcaag ccttgtcaag cgtatcttga ttggtatgct
    20881 ttgtggggaa tcctaggact gacccttcct aatctctcag ggattgggct actcggggat
    20941 ttattcgttg gaggtctaaa agctgttgct cctatcctag tctttgctct cgttgccaat
    21001 gccctttccc aacatcaaaa gggacaagat agcaatatga aaactgttgt tttcttgtat
    21061 atcctatgat agggactttc gccgctgctc ttgtagctgt actagcaagt ttcatcgtcc
    21121 ctattgaaat taccctaaat agtgccaata ctgaaattgc accaccagat gggattgggc
    21181 aggtcctcag caacctcttg ctcaaactgg ttgacagccc agtcaacgcc ctgcttactg
    21241 ctaactatat tggaatctta tcttgggcag tcatttttgg aatcgctatg agagaagcca
    21301 gtaaaaatag taaagaattg ctaaaaacta tcgctgacgt gacttctaaa attgtcgaat
    21361 ggatcatcaa tctgactcca tttggaatcc ttggtcttgt ttttaaaacc atttctgaca
    21421 agggagtcgg aaggcttgcc aactacggta ttttattggt tctattagta acgactatgc
    21481 tttttgttgc ccctgtggtc aaccctttga ttgccttctt ctttatgaga cgcaatcctt
    21541 accctctagt ttggaactgc ctccgtgtca gcggtgtgac agcctttttc actcgtagtt
    21601 ctgcggctaa cattcctgtc aatatgaaac tctgccatga ccttggactc aacccagata
    21661 cctattctgt ttctatccca ctcggttcta ctatcaatat ggctggagta gcgattacca
    21721 ttaacctttt gacccttgtt acagttaaca ctcttggaat tcctgttgac tttgccacag
    21781 cctttgtcct cagtgtggta gcagctatct cagcctgtgg tgcttcaggt attgccggag
    21841 gttccctcct tcttatccca gttgcttgta gccttttcgg tatttctaac gatattgcca
    21901 tacaaattgt tggggttggt tttgtgattg gtgtcatcca agactcatgt gaaacagccc
    21961 ttaactcttc tacagatgtc ctctttaccg ccgttgccga atacgcagca acccgtaaaa
    22021 aataactcat caaggcaagc ctgctcatgt cttgtctttt acgcttttat tctaacttat
    22081 taggaaattc ttatgtctat tagccaacgt acgaccaagc tcatcttagc tacctgtctt
    22141 gcctgcctgt ttgcttattt tctcaatctt tcgtcagcag tttcggctgg aattatcgct
    22201 ctcttgagcc tatctgatac gcgtagaagt actttaaaac tggctcgcaa tcgtcttttt
    22261 tctatgcttc tagctctggc tatcggtgtt ctagcttttc acttgagcgg atttcatatc
    22321 tggagtctcg gcctctatct ggccttctac gttcctttag cctacaagat gggctgggaa
    22381 attggcatca caccaagcac ggttttggtt agccatctct tggttcaaga gtcaacctct
    22441 ccagacctcc tagtcaacga attccttctc tttgctatcg gtacaggatt tgccttgctt
    22501 gttaatctct atatgccttc acgagaagag gaaatccagc actaccacac gctggtggaa
    22561 gaaaagttaa aagatatcct ccagcgcttc aaatactatt tatccagagg agacggacgc
    22621 aaccgagcac agctggtagc agaattagac acgcttttga aagaagccct cagactggtc
    22681 tatttggatc actctgacca cctctttcac cagaccgact accatatcca ctactttgag
    22741 atgagacaac gacaaagtcg tatcctgaga aacatggccc aacagattaa cacttgtcac
    22801 cttgccgcca gtgaaagcct gatcttagcg caactctttt caaaaattgc aggtcaactg
    22861 agccagacca atcctgcttc tgatttgcta gatgaaattg aacgttatct ggaagtcttc
    22921 cggaaccgca gtctgcccaa gacaagagaa gaatttgaaa cccgcgccac ccttcttcaa
    22981 ctcctacgtg aagccaaaac cttcatccaa gtaaaagttg atttttacca aaaatataga
    23041 cagtaatact cttcaaacca cgtcagcgtc gccttgctgt atatatgtta ctgacttcgt
    23101 cagttctatc cacaacctca aaacgatgtt ttgagctgac ttcgtcagtt ctatccacaa
    23161 cctcaaaacg gtgttttgag ctgacttcgt cagttctatc cacaacctca aaacggtgtt
    23221 ttgagctgac ttcgtcagtt ctatctacaa cttcaaaacg gtgttttgag ctgacttcgt
    23281 cagttccatc cacaacctta aaacagtgtt ttgagcagcc tgcggctagc ttcctagttt
    23341 gctctttgat tttcattgag tataaaaaag aaaacttcag accaatccac aaaaggtgaa
    23401 tatctgaagt tttcttttat ttataagtaa tcaccataaa ggttaatagt agaacaaata
    23461 aagccaaact caccaataaa gtgagcacct tgaccaaggt gttgctctgc cagtagcttg
    23521 gtttaccaat attactagtg gcatccatgg aaaatagttg attttgacgg ggttgtatag
    23581 ttaccaatac aatcaaagca agagatagga taatagctaa aacaattagc atttcaatca
    23641 ttgatctacc tcaaaattcc caacaaagta aagagcaaac caatcagaat cattaagccc
    23701 agtaaaagtg aaaaagtttt actaatcttc tcccctcggg tttctttttc cttcttgatg
    23761 ggtttttgtt tcaactcttc catgcgacct tcaacgtctt tgtaaaataa atcttcctct
    23821 gacatgttag cctcctaaaa cagtttgcat tatttcttga tatcgcacca agtcaacata
    23881 atttgcatgt tggccttgtt tgccaagtgc ctgacgcatt tgatcaacat ctgaaagggc
    23941 caatttaatg gtctcaacca aggcagcaac ttcactactt tcaaatagat gttctggagc
    24001 gatataaagt ctattgtgaa ccgtttggtt aaatccaaga atcaagagat tgtgctcaaa
    24061 ggcctgacgc actgcctgca acaactcatt gctgtgattg atatccaagt aaatatccga
    24121 cagttgatac agctcctgaa tcttctgtgg actagcattc tggtaaagga ccacattagg
    24181 atagcgaagc atgtctaaga gcttagaaga catctctgtc actgctgcga tacggaaggt
    24241 aacatcaggc aaggcttcta cgattgcttc tacttgctca atctgatctg aattggtcaa
    24301 gattaaggca tctcgtctta ggaaattatc acgtttgaac tggtaatgat aacccaagtg
    24361 cacaaactga tcatggtatt tctcgtcagt taactctaaa gcgcgctcat aagtcgcctt
    24421 atttggaatg atgatcttct tagtacgcac attatcactt tccaaaatca actgcatatt
    24481 acctggaatg gcatcataga gaggttcctg ccataccaag acatccgagc cagatttatc
    24541 tggatgatgg aaggaaacca agaaaggagt cgctagagta ttaaagataa gctgactggt
    24601 atctatttcc aaatcttgca aaaagaaggt gataaattca actttatttg caaagtaacg
    24661 catggactga ccaggcaaag tcaataagat atcacccgtc acatggtttt ccagtaaaac
    24721 ttgttggcca ttgacatctt ggtaaactgt cataatcggc tcgctatctg cgctataagt
    24781 ggttttagca aagcaagcac caaagcgatt gtagtggtca acctgacgta ctcgaccttc
    24841 taggtctttc cagtctacct gtttaaccaa gcgagcctgc attccatcaa cataatgaat
    24901 gacagccctc tcctgcgtca catcttcaat acaagcagac tgattatctc ctaaaatttc
    24961 ccaaaaatct gaaacgggaa cttggttaaa atagagaggt tttccatcct cgtaacctag
    25021 ataataggta aaaggagaaa gcagaccatc aggcagaaaa ccatctgcat cgatgaccac
    25081 tccaagttga gaaagaccag tagcgactag actttcatgt aaatctctac tttcttgact
    25141 gtaactatca taaagttcaa tcatggagca cctcctctac tgttttcttc cacttttcta
    25201 aaatttcttt ggtcaagaag ccttctgcaa tttgataaga ataggcacgc atagcttcca
    25261 aacgattttc ttgatacaat tgacaaatct tagcggcata agcttgcttg atttggtctt
    25321 ctacatggtc agatgaactt ggaatcaaat aaccattttg cccatcctct ataaaggtct
    25381 gattaccata aggcacatca aaaccaatta gaggtagacc tgaaccaata gcttccatca
    25441 aggtcagacc aaatccttcg ctggtagaag ccgttaagta gacctcatac tggctataaa
    25501 tctgcgaaag ttccgcatgc cccttgagtt ggatatagtc ctctgcctga tgatttgcaa
    25561 taatttctct aagcagagaa tcttctccac cactaccata gatatcaaag gttagttccg
    25621 gtaactcctt atgagcttca atcacagctt tcacaagcca atcaatgtgc ttttctttgg
    25681 caagacgtga agccgtaatc aatgaaaatg gtttgcgccc ttgacttgaa tctgtcaagg
    25741 aatcaatact gcctacagga atggtaacaa tctttggctg atgctgagta tatttggcaa
    25801 attgctcttg tagaacttca ttttgtctat cagtagacac gataaagaag tcaaccttat
    25861 ctgcattggt aaactgatag tcataatagt tattccaaag gatatagtcc tcatttgtag
    25921 cattttcact ataatgctcc gcatgaacaa ctaccgctag atgtgctgtc tgtgcttcct
    25981 caaacacaac ctgtccaata cctgtctccc tatccagaat aaccaaatca gacttgttca
    26041 aattcaaaga tttcataaag gcacgcacaa aagcttgctt tccatagaaa atcttatcct
    26101 tgaaatgata aacttcttcc ttcccttgat tcatcaaaat atcatagact ggagtcccgt
    26161 cttcattgta aaaagttcgt tggtataaga ctgcaacatt gtccttggga gcaaaatact
    26221 cgctacaata acgcgtataa gaaaagtaat ccttccgaat caggtttccc ttaaaaacat
    26281 actcggcatg ttgaaccaag tccttgttct catcaaccaa ataacaggtt acaaacttat
    26341 cttggtcaaa aaagaataca cgtaaaacct tgccattttt ttctctgtga ctttcttcac
    26401 caccaaagta agccaagaca tcatccactg tcacgctagt aggtgcaatt ttgatatctg
    26461 tgaaatgatt ataaagccag ataacctgat tatcatcaaa accaatattg gctgttaagt
    26521 gctgaatatt atcggctaaa atcatatctg taaagataaa cttagaggac agatttaatt
    26581 tccgaaaaac accagcacga taggcttgag cgtattcaac accgctacta gcccaaccaa
    26641 ttcctaaatt tatattgtaa attgtcatat tttctcctct tatggaaaat gagtcacgat
    26701 ttcacctttt ggagtgacct caaccagccc catcaggaga ttacgcacca tatccgcacg
    26761 gatttgttct ttcatagctt caaagcccgc gtaggcttct tgatagtact ctacgattgg
    26821 atttttctga ctagcagatt gaccaccgat agccatggat agctgttgta gatagtctac
    26881 ctgctctacc cagttgtcat caatggcttt aagcagtgaa agtcgtaaaa actgttcata
    26941 taagtcatgt tgattaagta attctttctt ttcagaaagt tctttatcaa tcacctgctt
    27001 cataaagcta cgaactgcag ttttgtcagt tacatctata taatctggaa cctctttaac
    27061 atgaaaacta atattggtca caataaagtg aaacaataat tcacgactag catagtgatc
    27121 agccgctacc tcttctgtat atctctcaat gatatccaca acaacatcct ctaagtcacg
    27181 agaaccatct attagacgat ttctctcttt atagactata tcccgttgta tattcatact
    27241 ttcagcatac tccagagtct gacgacgtgc tgaacgtcca gcactatcac tggcatgctg
    27301 agccttttcg actagtttcc ggtatttacg acctttcaat acttccggtt gagtcatatc
    27361 ttgaacctga tagtctttgt actttttatg cacccaagat ggaccaaatt tcttgataac
    27421 atcatcctct aaggatacaa aaaatttact cataccagga tctccctgac gaccagaacg
    27481 gccacgaatt tgtaggtcga tccgctgact ttccatccgc tcagtcccaa taacaatcaa
    27541 gcccccaagc tctgcgactc ctttaccaag cttgatatcc gtaccacgtc ctgccataga
    27601 ggtagccact gtcacagccc ccatctgacc tgactcggag ataatctgag cctcacgcgc
    27661 cgcattatta gcatttagga cattatgggc aatcccttca cgaaacaaga gagacgaata
    27721 gagttgagac atttcaactg agcctacaaa aacgagtaaa ggatttccct tagcatggta
    27781 ttgcttgatg tactccaagg atgcatacac tttttcaggt aaagtgatat atagattatc
    27841 tggatagtca atccgttgtc tcggacgatt ggttggaatg cgtactacag acatattgta
    27901 agtttcaata aactcttttt ccgcgacctt acctgtccct gtcataccag atatcttatt
    27961 aaacatctta aaaagactct gataggtgat cgaggccata gcccgcgtct caggagataa
    28021 tttgacatgt tccttggctt caatagcctg atggagacct ccttgaagtt tagtcatttc
    28081 cattagacgc cctgttccct tatcaaccag taccatctca tttccacgaa tgatatagtc
    28141 cttatcttta gtaaagagct tatgagctcg aatcgcataa accaaatgac gagcaaaaga
    28201 cgcatgctct tccttgtata aattatcaat ccctaggaaa ttctcagcag acttggcccc
    28261 cttagtagtg agccaaacct cctctttctc ctctttaaag atataatcct ctccttcgac
    28321 caaggttgtt acaagtgtat caatgatcgc atagtaatta gactgaacac gaggagaacc
    28381 cgcaataatc agaggagttt gtgcactatc aagcaagata tcatcaattt catcaataat
    28441 aacatagtta aacggtcgta aaaacttacc ttcttcattc gaggctaggt tatcatttag
    28501 ataatcaaaa cctaaactac tattggttgt gtagatgata tccgaagcat agataagctt
    28561 cttttcttca gctttcattt ccttctttgg atcttccgta aatggtacac caatggtcaa
    28621 tcctagaaaa cgataaactt ggcccatttc ctcggcatca cgctttgata aatactcatt
    28681 aggagtcaca accatcactc cttctcctga aaaagcgttc aaatagacag gcatggtagc
    28741 tgtcaaggtc ttaccttccc ccgtattcat ctcagcaaca tttccatagt gcatgacaat
    28801 agctcccatg acttgaacat cataggggaa catccctaaa atccgcttat ctgcttcacg
    28861 caccacagca aaagcttcaa ccaaaatatc gtctagactt tctccctcgg aaagacgctg
    28921 acgaaactct actgttttag ctactaattc ttgatccgaa agagaggaca tcttgccttt
    28981 cagggcatta atctgcttta aaatcttttt cactttccta agctggaaat cttgacctaa
    29041 acgtctaaac acttctgatc tccttgatag aaaaatgata aaaagttaag gactcaaatc
    29101 cagcacttaa aagagaaact tgataagtat aactatcttc tggataagta aatatgaaat
    29161 ctttcgcttt ttctaccttt ttttctaaaa tatcaccata gcggtcaaaa aaagttatct
    29221 tggtataaac tccattttca ggctgacaat caaaaaccag tgatagttga tactcctgct
    29281 ttctttttaa taagggaagc tgaggttggg ttcgtgcagc ctggtaattg acactagaaa
    29341 accaagtctt tagaatctca ccagatggca atagaggatt atacagacga acacttttgt
    29401 caaggtaata agatacagtt gttccataca tataagtccc accaacttct ccccaataaa
    29461 tagactgtct ctgtgtaata atcatctttt ctcccttcca aaaccagtct ctaagaccat
    29521 tctataaaag tgcaaaaacc aagaaatatt ggtatctgta tcatcattgt gtcgtccagc
    29581 agttccttta gataaaatct tcgcacctgt attacacaga taagacacta attgttcata
    29641 ggcttgtgga tccatttctt catctttcat ataggataaa ccaaaggttg tctttgaaaa
    29701 atttgcttgt ttaaaaattt tccaaaaacg ctgatccaac tccgtcatat cttgagaact
    29761 tgtcccacct gtatgatgaa ttaaacaatc aaaagctaag ttagagacac ccggtgcgtc
    29821 caaacgtcca cgactagcta tagttcctaa attagccaag ggcttaccaa ctatgatggc
    29881 atggggttca aaagaagcac cataatagag agccggaaac gttcccatag aaagacctga
    29941 taaaatcaaa tccttatgat caaagcctaa ataatcaaga tagtgagtga tcgtatcctt
    30001 tacttttccc tctagctcat ccgttccgag ataaaaagct cccccctcta aacgtggatc
    30061 agaaaataaa atgaagggac atccaagagt tttcatcata aagtaaccct cgaatccttc
    30121 tgcaggtcga taacctgcaa aatagacagt caaaggcggt ttaaaatcac ctggatggaa
    30181 gaaatagttt atttcatcac gcttggaatc atgtaggata tttccaccaa gtacaaactt
    30241 accaaattgt tttcgactcc atcgttggtg aagattacct agtttgatag ttccacgacc
    30301 tcttgcttca acagatatcg agagaaagta gtctccgtct cgactatcca taaaaagtgc
    30361 ttgctccaag tctttttcag atactattac ttcttcaaag aaatcatcaa cagacccact
    30421 ccacatttta cggattacta aacgaaagtc acaattgcct tccttctcat attcaagcca
    30481 caactcaata gggagtgttt tttgcaccat aatattataa gcccaatagg caagctgggc
    30541 aaaatcttgc ccaaactcac cttccaaact gacataatcc aatccttgat aagaaatagc
    30601 tcctgtaaaa tttggattga cttgtatcgt cggaggaaag agtttatcac catacccacc
    30661 gccaaaaaga gatttactta aatcattgat tagttgttgg ggacttaaaa aatcaattgc
    30721 ttgtgcacat cgttttttta gaaaatccac aacctctcta tcatttattt gtagattctg
    30781 gttatagaac aaagtataag gttcaaaata ttttacatag gaaaataagt ctctggaata
    30841 ctgaccatct tctattaaaa ctgcatgaaa acggttaata tcctcttttt cgattatttc
    30901 acgaagggtt tttgatgagt ttgggtaaaa ataataccaa ctcatatttt caggtatgtc
    30961 atagtgattt tcccaattgg caagtcctat ctgtaaaata ttaagttcct ttgacatttt
    31021 taacctcctc tatccatttc tctaattttc caagaaattg ttgtcctgtg tgctccttaa
    31081 tcttatcaat tgaatatatc aaggactcat tccactcctt caacctatct gtgtaataat
    31141 gtgcagcctt agaaaattct gtcacatctg tcagcaaata accatttttt aaatgttcca
    31201 catagacggt ttcaactagg ttgatttgag gaattcctgc actaatccca gcaatctgtg
    31261 tgtagagatg aggatgtcta tttaaatcca caatcaaacg gacaaattct agtgttttta
    31321 tcaaatctaa ctcatcattc aagttaacaa actgtaagcg taagtcctgg tgttgatttt
    31381 cttccagggg attttctgca tcaccataat caatcgcctt tcccagattt tcggattgaa
    31441 tgttttcttg gatgaaagac tcaacaatcc cttcaacctc attcatttgc tcctgactag
    31501 cagcaaaggc tccaaaaatc acctcagtat ccttattttc agcgacaaag gacaagactt
    31561 gaagcagagc ttgattatca atcccctgct caaaatccag ttgaaaataa atgatggatt
    31621 ctttcttagt ttggcttcgt cccaatcgta atcgggtgtc aaaagatgat aaatgataac
    31681 attgatgcat tcgttcagga tacaactcct gcaacaatcg taaactatcc tctctatcca
    31741 ccaaaatcaa atccgatttt tcaaaagtta catctaaatc cctaaaggta tcttgaggat
    31801 tacgtccaat gaacagactc aacagtttag gattagtact aggtaaacga tctagtacca
    31861 actggtcatg atgagaatga gaaggaagca taaaaatatc ctgatccttc acatacgttt
    31921 gcagataatt ctcaaaaaat tctgccacca gatctcccat attttgatag gtaagcattt
    31981 taaagcgata acccaaaatt ggattgactt ctacctgtcc tccttctttt aaacgctctc
    32041 taaattgcca aactccctta ggattcaaat attcttgata ggctgcttgc ccatcttcaa
    32101 aaaaaataat actcgatata aaccctcgat catccatgat atggtgcata tgtatttgac
    32161 catttggttc aaaatactgt atatcactga tgaagccttc aactccatgt tcaaccttag
    32221 caaatttctt cccatttttt tgaacgataa tcgtaaaggg actataaata aattcacagt
    32281 catcatccca ctcaatatct ctaatgctta aaacttgggt atggagatta tgaaaatctt
    32341 gcataacatc aaaaacggaa taagtatccg tttctaacac accatgtcta tataaaaaat
    32401 aacgtagatg aggctggtaa gctaatacta atagacgaga atctatatct tgctcttgaa
    32461 agagccggat ctggtgaaag gtatcatcaa actctagacg aaaatgagaa aaataccatg
    32521 gagtgatatc tgcatgccat gttctttctg acccatacca agctggaata aaataataca
    32581 taaaagtctc ctaaatcaaa ggtttatagg tctcatttag ccttaaagcc ttgacctcgt
    32641 ctctaatcgt aaaaatcatg cctccaaaca tcataaacaa acctggaatc attgccaatc
    32701 gtaataactt ttcatcaaac aaaacaaaaa gcatgggacc acctgccata accacattaa
    32761 agagaccacc tatgactgag aaacgaagga ccaatcgatt aataaatcga ctagtatccg
    32821 cacctggata aataccataa atgtattctc cagatttttt catacggtct gcaatctctt
    32881 ctccattcat cgtaacaaaa gcaaaaatga tactaaataa aaataagacc gaaatataaa
    32941 catagaccca caaaggcttt ccaatcataa attcctttga taaagccgct aaccctgaat
    33001 gattagggaa aataaatccc aacaagatga acaaataagc tggtacacta agaaaactca
    33061 tcacatacat ataaggcatc ccacctgcag gattcaacat gatttcgaga taaaaatagc
    33121 gtttaaatcg attgtgtaag ccaattttat taacaggaac caaatagcga gctcgataca
    33181 taagggcaag taaataagaa aagacaaggg ttaataaagc aagtaacaca ataatccctg
    33241 ttggaatgtg tactgtctga aatgtttcca aaacatcctg aggaatattt aaaaccatac
    33301 tggataggag aatgactata gaacctccaa tccccatact cgcatttaaa tctgacaacc
    33361 aaacaagaaa aaatgttcct gctatcagca atattgtatt cattagaaca accaatattg
    33421 cagaatagga ggattgtact ggcagtctca agctaactgc caatgattga atgacagcta
    33481 tcatcaaggt caggtacatt ttacggcgat cttgtatttc tatagacgta gatgttaaac
    33541 ccaaccgttt agaaaaagaa aacatctgcc ataaaatcat agctgacatc caaggggaca
    33601 atccaacaga aaaaattgac aaacttctta gatttccacc tgttagggcg gctgagaagg
    33661 ctagataggc tgttgaacct cctaaaaaat ctttagtatt taggtcaaca aaagggagag
    33721 taatacgact tcccaataca tagataaaca gtagaaataa ggtaaatagt ccttttttta
    33781 ctgctattga cgaataaatc ttagtcataa aacactcccc tcaccttcat tgtttgtgat
    33841 atggtaaata acaattcttt tatttcaact tttaccattt ctttgttctg catcaaaaaa
    33901 caactttaat ctgaaacaaa tatctttata ttcctcagta tctgttaatt gatggtattc
    33961 taaagtttgc ttataatctt ttaaaagatt gacaaatcga atacgcagaa cggagacatc
    34021 caaaccagcc aagacacaat ccgatatttt cttagaaaac acttcaacaa tatctcttgc
    34081 ccaggaaaga tcaaattccg ttctcatgat gcttcctgaa cgtcttctat acagatagag
    34141 attatcgttt ataaagacga ttttagaggc taaaagataa aagcgatgca tagttgcttc
    34201 atcatcaaag cggcgaccat ttgaaaagtg aacttcattg aataattctt ttttaatcaa
    34261 cttaaatgtc ggcaatataa aggccgagct attgaatttc caatctcctg cttgacggtt
    34321 cataatttct tgtatagcta attcttcgac gcaaaaatct tgccctgtta cataaaaata
    34381 aaaattcccg tcactttcgt cataattata gtaattccct ataacaacat ctgcatcctt
    34441 ttcttggact tgctgataaa gagtttcaat catattttct tttacgatat catctgaatc
    34501 aacaatcgtg atgtactctc ccttagctac actaatcccc atatttttag cttgtgctgc
    34561 ccccccttat tttcttgatg caatactcgc acacgattat cttgcatcat aaaagcatca
    34621 caaatttccc cagaattatc cgtagaaccg tcatcaacta aaataatttc tatattttga
    34681 taggtttgct tcagaatatg ctcgacacac tccactaaat attttcccgt attgtatatc
    34741 ggtaccacaa cactaattaa ttcactcatt actctatctc tatattcttc attctatcca
    34801 ctaaatcatc tggtctctcc acagaaaaaa taccgtcata gagtccatca tccatacttt
    34861 tacgtgtgat atcaaaagcg aagattttct tgccactttc ttgtgccctt gtaactacat
    34921 taaaaacctc tccacctgta ttaatatcta aataaactat agaatcgtcc aatagccaat
    34981 caattctact atgtaataca ttttgatata ctgttacatt cgtatactgt gatagagagg
    35041 tcagctcctc agaacaatca cacggtgcag ccaaatgaaa atgccaatca ggtaaccgtt
    35101 gtactaaata ctctaaatgt tttatatctg cactccatgt cacaagcatc acttgttttt
    35161 tagactgatt gcttctttca aaataattta aatcggaacg ttgaaaagca atctctgacc
    35221 aatccaaatc tctataaacc caccataatt cacgtagtct agatatacta tatgtattcc
    35281 aaggtttatc atgactagca tagtgaacaa ttgtaggtgg attgtcatct agacgttcac
    35341 attcttgagc aaggtgataa atatcaacac ccaccatata attatatgtt ttatctaagg
    35401 ctagccaatt atcctcaaaa taaatattta aaatactctg atccccaaga tgaacaactt
    35461 gattttgctc ggccgctaat tccaataaac tattgacaat agagtgttct ttccattttg
    35521 caacatccat tagtaacata ccagcattaa atccagattt tcgtccttca taggcataga
    35581 catcatcaac agcaccaatt gaatatcctt tgagatctat ctcaaacaaa gtagctagtt
    35641 ccccagttac aatgatatcg gaatccagat acaataccct atcagattca accacttctg
    35701 tcgcaaaaaa tctaaagtaa gaagcataat ttatatgagg tcctgtttta tagctttcaa
    35761 aaagttcttt atcaatgtgt acactgcgaa ttgtagaatt cacaacttcc atttttctcc
    35821 ccaataattt aaaccattca ggagctatat cactgttgag aatataaaaa tcaacatctc
    35881 tattgtgata caatacagac tttatagtcg tctctaaagg aataagatag gcattatctg
    35941 ccgctaatac tattgatttt ctcatactgt tctctacctc atgtaagatc tgattgctgc
    36001 aaccattttt ttcggaatgg agcttggata gataccttca tatgaaatct cagaaagatt
    36061 ttcagagcaa gtattgtcga aagctatcat tggttttttg tacttaagca caaactcata
    36121 tgcatcttct aattttcgat catgattcaa atccaaatac aaatctgaag ctattactat
    36181 ttgttccaat aacattggta aggaatttgg atatacggta acattaggaa aacgcgttaa
    36241 agctagtagt tcatttgcca tatttgtata agcaacaata tgaaaatgaa cttctggcaa
    36301 ttgctccgcc aaataatcga ttttctcgac acaccaagaa ttcgttaaat taacacattg
    36361 taacttaaat atttgtgatt tactaggata cttcacactc tttgaaaacc attcatttaa
    36421 aataacagac caatccatca aagagtattc ccaccaaact tctcttagac gtccaacaga
    36481 aaattgattc caaggcttat cctgagaaat atagtgtaaa attagtggca gtggttcgag
    36541 cggaatatca aaaatgaatt gatgtttaaa ggctgccgcc ccataatcat atcctatttg
    36601 aaaattatat tgatcttcaa gggaactata ttgatcttta aacaacatat tcaaaattga
    36661 ctggtctcct tcttccacat tctcatgttc tttttctgtt aagtcaatca atttttgtcg
    36721 aatagtttca gatccccatt ttttgttgtt aatcaagaga acaccagcat tgaagccgac
    36781 tcctgctcca aagcaagaac gagctgctgc caaataattt tcacctaagt ctaattcaaa
    36841 caaatcggtc aaatcaccag tcacaatcaa atcactatct agatagagaa ctttatcttc
    36901 tgttacaaaa tctggaataa aatagcgtgc aaatgtcata tgattgatat gaggtaattt
    36961 attagaccaa ttcatttgaa actgtgagcc aattaacttg cagtcaatca agtcgccccc
    37021 catctcttgt aaatatattc ttatttgact aaaccattcc tgaggaatgt cctgatttag
    37081 cagataaatt ttcaaatgac tattgtgtct acagagtgac ttcatcgccg tttcgatttg
    37141 tcgaatataa gcgtaatcac ctgcaaatgc tacagcgcgt ttggtatttc tcattttaaa
    37201 tccttatcat ttattttaaa tagtctagtt taatattcgt gcaacaatct gactgttata
    37261 ggtttcatca tcaataaatt caatatcttg atcaaaatta tactctgcag tatgtttatg
    37321 agaaaattta accttagttt tagctcccat tttcatccat tcatactctg agtcaatatg
    37381 gcctacatcc aaaacttgat agcccatctg gcatagatta taactcagaa cttttgctgt
    37441 aggacccagc atacataaaa tcaagcgacc accagcatac ttttcaattt cttgttcaat
    37501 ttcatgaact ctagaaaagg cactatgaga aggacagata attcgcttaa tagaatttgc
    37561 ctcatcgaat aaatcatttc cgacacctga acgagaagtc gcaccttcga ctatcagtaa
    37621 gtcacggttt tcccaaatgc ttttcaattt ttcaaattga gctttagctt gactcttgtc
    37681 ttcaaaatcg atataagggc gagatacaaa ggttgagcca taccatgaat cactgcataa
    37741 ctctctgtaa aaatccatat aatgatccat gtgatctttc caaaatggaa tcgcccacga
    37801 tgtaaaccta aaacgatctg taaaagcatc aggaaggcac actactaaat cttctcgact
    37861 ttcttggccg ataatgtccc tcatgattga aaccaactct tcatcataat cctggtaggg
    37921 aattgaatgc cctgcaagca tattgatttc cccatctcca aaacgaacta aagaagagtt
    37981 gtgttcaata atataatcca aggtttcatc tatccctttc acctggatta tatcaagcgg
    38041 tttttctagc atatccttag ttatcaattt ttgcaaatca gccaacattc gttcaggatg
    38101 ttcacttgaa tacaaccttt ggccattatt cccattttga gatttataaa aggctagtat
    38161 aggtttagat agatgagcca tttctgcaac gatatcggat gttgaagtca gtaggttgat
    38221 atctaaataa gcatccatct tctccttcaa ctcgtctagc ttatctctag aaattgccgg
    38281 atagagctga atattaggat aacgattaga caaatcatat aattttggcc ccatagctgt
    38341 ccaagcagca acttgaaaaa caacatttgg caactgtcca gccaagtaat ccaattgttc
    38401 gatatcctga gaagccgtaa acgttaaaca agttaaactt ggaagttgtc gaaaacaggt
    38461 aagatgtccg tttttcttaa aatctttaat cgtatcaatc ataaaggaaa ctttcccatt
    38521 ttcgaaaacg atttgtccta actctccgtg ctgagtcgat tgaaaagcta gtagcgtttt
    38581 ttcttgttct tgcaaagatt ttaaaaagtt ctcatctgca ctaccatgat tgatatccaa
    38641 atatagattt gttgactttt tcagcttatc taatacagga ggaacaattt gtggatgcaa
    38701 tctcacatta tcatacacag ctaattttat cagcttatca cccatatccg tccaagcagc
    38761 aatatgaaat accacatctg gtaaagctgt gactaactct tctattcctt ctaaatcttg
    38821 ggaatttgtc aaagttaaac aagaaaattc cttatctaaa gacgatgtca gttcaaactc
    38881 ccctatatga tgttgtaaaa ttttagtcca ttccaaatca tgaaattccc accataaatc
    38941 acgataacga ttggctatca aggtggtcca gggttttctg taagacacaa aatgaataat
    39001 actaggaggt actaactcat taaaataatt ttcccattta ttataaaaag cagttacatc
    39061 atgacccact tgaaggttaa attctttatc cagctctaac caatcatctt gtaagacctg
    39121 attaaaaatc gtttgatcac cattaaaatg ctcgaaacgg ccttcttcaa cttccttcat
    39181 tgtaacaatg ctctgttcaa ttagtcgttc ttttaatttc tcttgacgcc attttttatt
    39241 gttgattaat aaaacacctg cattaaatgt aattccatct gtatctttaa ctgctgcgag
    39301 tgatttttct tctaaacaaa tactaaataa tttctctaaa gaagtattta caatcaaatc
    39361 actgtctaaa tataaaacct tatcttcttg gatataatct gcaataaaat atctagtata
    39421 ggtaatgcta ctaatgtgat cttgcttttc ccaatcttga aacacagttt gttcaggtag
    39481 cttcacatcg ataatctcac tacctaacat gcgagctatt tttcgtggtt tgcgaaacca
    39541 atctggcata atatcttgat ttaaaatata aatcttaaca tctcgattgt ggtataaaat
    39601 agattttatg gttgtttcta actgcctgat gtaattacga tcaccagcta atacaattgt
    39661 tttaatcatc ttgttctctt attcaactcc caaatggtaa attgcatcta ccaataattt
    39721 tttagtaaaa taaccttctt ttagcaaata actaaaggtt tttatccgat tcgtcatttc
    39781 ttgatattct tgtagattca ttttatcaac tatcgcatga acttcttcta gactattcgc
    39841 cacaaagcct aagccttgat ctactataaa tttagcagtt gacaagctac ttggtacaat
    39901 gactgggatg cccgctgtca gataggtact caccttatga gatatattta aggtataata
    39961 ttggttgctt tctccatcgt tttgataagt tccccagaca aggccaaatc caccctttga
    40021 taattctagc aacaattcct catctttttt ccatccttcg atgctgagat ttctagcact
    40081 agaactagct tcccctttat ttgaaaatac tctcaaaggc gtatcttgag accaattttg
    40141 taagtctgga aaacgctcta aacttccagc aaaaaaaagt tcttttttaa aagcaggggt
    40201 gtataaggat aaatcatgag gatgatccca catcccttga acaagaatct tcttagtcgt
    40261 caatccttct tccatcaggc gtgttttcat tctctctgac ggcactatca aaacatctga
    40321 tagattatac atgtacatat agtctttcat gagataatag ttactatcaa acatgagggg
    40381 aacaacatca tggataaagc aaataatttt cacctgcata tccttcaact tatcaaacaa
    40441 gagacgatca aattcaaagc cattccaggt tggagactga aagactaaaa tatccccaat
    40501 agaaatactg gccataatac catccagacg cttattcatt tcagaaggac tatctgaagc
    40561 aatgttgtaa aaataaatac caacctctct aaatcccagt tgactagcta tcttttgaac
    40621 agcattttga gctaagataa ccgtactatc accagccatg ccgtataaat ttgttaaatg
    40681 tagtttcata ttacgctatc tcatttttta ttactatcta cggaagtaaa gacaattttt
    40741 ccatcattct tctataaatc tctgtgaact gcatattttg ttcttctaat tttgctatca
    40801 ctctttgtaa tctattttta taaatcaaaa tatgattggt caagtcatag tctgaacttg
    40861 ctaaaatagc tatcttttct tccctagccc cgatttcatc atacatacgc ttttcactcc
    40921 atgtattcga taaagtatca gataaaccaa cacggtacca gtaaacacaa cgattcaaat
    40981 agactatcct cgaagctctt agaagtacct tccatgtcca gtaagtatcc tctgcaattt
    41041 ttcctatagg aaatggtaaa tcttgtagta actctctctt gaataacttc aagacagcta
    41101 cagtccagtt cccatttctg acttcttcga caccttccct atccatgatt gctttacctt
    41161 ctatcacttc cagagaatca tctggatccg taacataagt catatacaca tagcgtgttt
    41221 catcataaga attataacgc ccgatactaa tatctgcgtt ttcctttttc aaagcaccat
    41281 ataatcggtc taaagcatca tgttccaacc aatcatcaga gtctacaaaa gtaatgtacg
    41341 ccccccccga acattcaata cctaggttac gagctgatga aagaccgccg tttgctttct
    41401 caaaatattt gaaacgagaa tctttctcta caaattcttc acatattttg gatgaatgat
    41461 ctggagagcc atcattaacc atgatacatt caaaattcgg ataagtttgt ttttgaatac
    41521 tatccaaaca ctgtcgcaaa taattctcaa cgttgtagat tgggactaca atactaatta
    41581 gttcattttc catatactaa ctttcctaga cttgatttat tctatttccc tcttaatctc
    41641 ttctctttac aacaagattt ccattattat aaactacact gtttgatgga atatcattgc
    41701 gtatgagaca acctgctcca ataatggtat tatccccaat cgtcactcct tttaaaatcg
    41761 tgacattact tcctatccag cagtctctgc caactctaat cggcgctgta gtccactgcc
    41821 acttttcaat cttttcagca gtataaatat ggtcgtgatc ataaaaacga acaccctctc
    41881 ccatcatggt accagctccg atttcaattc tttccataca gttaaaacta caagagttgt
    41941 tgataaaaac accatcatgc agtattaact taccagaaga gacatgaaaa ttttcaaaat
    42001 ttctgcagat gacatttgct cctacaatga agtgagcctt atcatcgatt ttaaagacat
    42061 tccaagtccc atcttggatg attttttctt gatgattggt gcctactctg acttcattca
    42121 gatagtctct cactctagaa accaatttgt ctggtgtact tgatagaaaa acttcctgcc
    42181 cctgatttcc atggactgta ttgtcaaaag caaagacaga ttttccagcc tgtacaaact
    42241 tggagacaat agcatctact tcttgaaagt gattgatatc tagtaaaaag tcacaggtat
    42301 cgactagaaa gtttagctgt tcttcatttg taatcgttcg gagacggaca ttatagttcg
    42361 tttctaagct acggattttc tcggaaaatt gaacaggtgc tgcaatataa aaacagatat
    42421 ttggcaagga ttcaaggaga taatccaact cttcaatctg atcactaaca gtcaaaatca
    42481 gagcatctcc tactaaatga tttttcttca tttgcttatt tctctcaatt tctcaatcat
    42541 tgcttgaact tggtcaacag catatacctc ctgacctgct tcataggttt tggtattttc
    42601 aaaggacaaa atagtttttc caagtcttgc aaattgattg ataatttcct ctgttttttc
    42661 accatgatta atatctaaaa gtacttgact ggtttctacc aattcattat cgacatctac
    42721 caaatagtga attccgttaa atatagtcac gtttggataa attgtcatct gagccaatcg
    42781 atcactaact attactctag ctgctatctt aaactgaata tcaggcaagg attgaaccaa
    42841 tgtctcaatt tgttcaatat ggtctgaggc agtatagatt agacaagtga aaggttcctt
    42901 tattggatag atgtgagatc tttgtaatgg atgtaaatga tggttttgtc ccaattctgt
    42961 ccattcaagc ccatgatagt accaccaaac ttcacgatag gtttgggccg ccaaatcttt
    43021 ccacggtttc cgatgagaaa gatagtgaat aatagcagga taatcctgac cctcaggcaa
    43081 ttgataatca gcaaactgtt tatgaatgac aatatgatta taatcaaagt ccaattccaa
    43141 ccatttatgt tcaaaaagca tattcaagat gctctgatct gcctgatcca ccttatcatg
    43201 ccattcattg gttacatcaa ttaatttttg ggtcatattc tcttttttcc aaaaagcatt
    43261 gtttaccaag agaacaccgg cattaaagat ttcttgacca aaataagctc tgcccccaaa
    43321 atctctaaca gcagccaaag gataatcttg taagtctgta gcaaacaaat catcaagatt
    43381 tttcgttaca agtaaatcac agtccaagta gagggcctta tcttcttgca cgaaatcagc
    43441 tatgaaatag cgtaaaaaaa ctgtgtaact aatatccgtt ttataacatg aaatttgctc
    43501 agaagttacc cgacaattaa taatttctga gtcaaacttc tctaagcgct tatttaattg
    43561 cttaatccat tcatttggaa aatcgctatg aatcagataa aaacgaatcg aacgattatg
    43621 ataacaaata gacttgattg tcgttaaaac ttggtctaca tagccatagt ttgctgctag
    43681 gacaatggct ttcttttcac ttgattcttg taccgttaac tgatttaaaa gtcttttttt
    43741 catttcaaac tctttatata ttgctgtgtc agataaacca ctagcttgac cgttggcgag
    43801 actgacttcc aacatctgac gataaactgc caagtgtttc tctagaggat atcccatatt
    43861 agctagtagc gtaatacgtt cagacatagc atcaactaag gcgtgcatcc acttttctgt
    43921 ccaaactctt gatagactac cttttctaat ccgataagca taaagacctt tatttaaata
    43981 aattaccttt tccgataata aatatacctt ttgattgagg taaccatctt ctcctaattt
    44041 acccatgtca aagcgcaact gctcaaacaa tcttgcctta tagagtttac cacaagcaga
    44101 tatcaaagca aaactcttca tttcttgagt ttcataacaa gttctcaaag atggaaacat
    44161 tgtcatatac cttatcataa taggagtctc ctgatatatg aaagtagaac attccttcac
    44221 tttcgttgaa agaatagtaa ttcccaactg caatatcagc ttgatattct gttatttttt
    44281 tatatagggt ttctacataa tctaactcaa tccaatcatc tgaatccaca aaggtcacat
    44341 aatttccgga catattattc agaccggtgt ttcgtgcggc agaaatacca gcattttctt
    44401 gttctatata gagaattcgg tgatccattt ctgaaaattc tttacaaatt tcacctgaag
    44461 catccgtaga accatcatta acgacaacaa tctcaatatt tttatatgtt tgagaaataa
    44521 tactatctag acatttcctc agatagtttt ctacattgta tactggtaca atgaccgtaa
    44581 ttttatcatc cactagcaat tttctccttg atttatgtgc gcgagttagt ttagcctaac
    44641 tttacaggtt gtcttactct tcttcatcac gtttacggcg tttcgcaacc aatccaatac
    44701 ctgtaacagc tgctagaact ccaagtaaca cagatccaat tgacgactca gtacctgtat
    44761 taggcaattc tttttgggat ttacctgtcg atccagaagc atttccaact tgtgagttcg
    44821 aatggtttgc tgaatttgaa actgatgtac ttgctgaggc tgacgcactc gttgatgctg
    44881 actcagacgc actggttgat gccgattcag acgctgaggt gcttgctgat gctgaggcac
    44941 tggttgacgc tgaagctgag gcgctagtac ttgctgaagc cgaggcactg gttgatgctg
    45001 aggctgaggc gctagtactt gctgaagctg aggcacttgt cgatgctgag gccgaagcac
    45061 tggtacttgc tgaagccgaa gcactcgttg atgctgaggc tgaagcactg gttgacgctg
    45121 aagctgaggc actcgttgag gctgaagccg aagcactcgt tgatgcggaa gctgacgcac
    45181 tggtacttgc tgaagctgag gcgcttgtgc ttgctgaggc cgaggcactt gttgaggccg
    45241 attcagaagc tgaggtactc gttgatgcgg attcagatgc tgaggtgctt gctgaggccg
    45301 aggcgctggt tgatgcagaa gctgaggcac tggttgacgc tgaagctgag gcactggttg
    45361 aggccgattc agaagctgag gtactggtgc ttgctgaagc tgaggcactc gttgatgccg
    45421 attcagacgc tgaggtgctt gctgaagctg atgcacttgt tgatgctgag gctgaggcgc
    45481 tggttgatgc cgattcagac gctgagatac ttgctgaggc tgaggcgctt gtacttgctg
    45541 aagtcgacgc actggttgag gccgattcag atgctgacgt acttgcactt gttgacgccg
    45601 atgtgcttgc acttgtcgat gctgacgtgc ttgccgatgt acttgtgctt gttgatgctg
    45661 acgtgcttgc tgaagccgaa gcactggtgc ttgctgaagc cgatgcactt gtacttgctg
    45721 aggttgatgc cgattcagac gcactcgttg atgcggaagc tgacgcactg gttgacgctg
    45781 aggctgacgc actggtactt gctgaagctg aggcgctcgt tgatgccgat tcagacgctg
    45841 aggtgct
//
LOCUS       DAVBCA010000009        45402 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.009, whole genome shotgun sequence.
ACCESSION   DAVBCA010000009 DAVBCA010000000
VERSION     DAVBCA010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 45402)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45402)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45402
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.009"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            434..886
                     /locus_tag="VQU19_000458"
     CDS             434..886
                     /locus_tag="VQU19_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET2479763.1"
                     /translation="MIITKISHLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVQLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            905..2242
                     /locus_tag="VQU19_000459"
     CDS             905..2242
                     /locus_tag="VQU19_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HET2479764.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            2321..3205
                     /locus_tag="VQU19_000460"
     CDS             2321..3205
                     /locus_tag="VQU19_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2479765.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            3205..4038
                     /locus_tag="VQU19_000461"
     CDS             3205..4038
                     /locus_tag="VQU19_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET2479766.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAIFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            4056..6149
                     /gene="nanB"
                     /locus_tag="VQU19_000462"
     CDS             4056..6149
                     /gene="nanB"
                     /locus_tag="VQU19_000462"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HET2479767.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISPLLLDKLSGESQTVVMKFKADEPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKRSIDEISLFNKAISDQ
                     EVSNIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLRERHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNREESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSEVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            6161..7264
                     /locus_tag="VQU19_000463"
     CDS             6161..7264
                     /locus_tag="VQU19_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HET2479768.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            7438..8136
                     /locus_tag="VQU19_000464"
     CDS             7438..8136
                     /locus_tag="VQU19_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET2479769.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            8155..9672
                     /locus_tag="VQU19_000465"
     CDS             8155..9672
                     /locus_tag="VQU19_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HET2479770.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADLAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFLGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPFGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            9797..11125
                     /locus_tag="VQU19_000466"
     CDS             9797..11125
                     /locus_tag="VQU19_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2479771.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            11377..12243
                     /locus_tag="VQU19_000467"
     CDS             11377..12243
                     /locus_tag="VQU19_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2479772.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            12259..13098
                     /locus_tag="VQU19_000468"
     CDS             12259..13098
                     /locus_tag="VQU19_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET2479773.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            13371..13823
                     /locus_tag="VQU19_000469"
     CDS             13371..13823
                     /locus_tag="VQU19_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET2479774.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNQFEHHKNYADLHLLIEGHEYSSYGSRIKDEAVAFDEATDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPTGYAGMEEKVRKYLFKILID"
     gene            13920..14264
                     /locus_tag="VQU19_000470"
     CDS             13920..14264
                     /locus_tag="VQU19_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2479775.1"
                     /translation="MVSSKHAARASFLDGQEITVDEMSWIINGIVNALIGRYIKLGTY
                     AAKYGIGIARSILSRAAATAAARVGLLTKISGWILRVAVNVADVYGNFANNIAAAWDA
                     YDKIPNNGRINF"
     gene            14548..15192
                     /locus_tag="VQU19_000471"
     CDS             14548..15192
                     /locus_tag="VQU19_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HET2479776.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLSWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            15361..16278
                     /locus_tag="VQU19_000472"
     CDS             15361..16278
                     /locus_tag="VQU19_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HET2479777.1"
                     /translation="MSDLKKYEGVIPAFYACYDEQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGAKAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTATHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKESFL"
     gene            16296..17180
                     /locus_tag="VQU19_000473"
     CDS             16296..17180
                     /locus_tag="VQU19_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET2479778.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(17196..18047)
                     /locus_tag="VQU19_000474"
     CDS             complement(17196..18047)
                     /locus_tag="VQU19_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HET2479779.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANRVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            18247..20304
                     /gene="pbp2b"
                     /locus_tag="VQU19_000475"
     CDS             18247..20304
                     /gene="pbp2b"
                     /locus_tag="VQU19_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HET2479780.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTKRQLADYYLADPEIYKKTVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEINKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            20315..20911
                     /gene="recR"
                     /locus_tag="VQU19_000476"
     CDS             20315..20911
                     /gene="recR"
                     /locus_tag="VQU19_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HET2479781.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            21087..22130
                     /locus_tag="VQU19_000477"
     CDS             21087..22130
                     /locus_tag="VQU19_000477"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HET2479782.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            22214..23587
                     /locus_tag="VQU19_000478"
     CDS             22214..23587
                     /locus_tag="VQU19_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HET2479783.1"
                     /translation="MKLTIHEVAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGVRDGHDFIERAFENGAAATLSEKEVANHPYILVDDVLTAFQQLAAYYLEKTAVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPTDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQVLDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIRLAFQHLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGVQSVQLHNQMILSLSPDVLDTVIFYGEDIAE
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAHDQILLKGSNSMNLAKLVE
                     SLENEDK"
     gene            23574..24185
                     /locus_tag="VQU19_000479"
     CDS             23574..24185
                     /locus_tag="VQU19_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET2479784.1"
                     /translation="MKTSDFVKYLQRMIAITDTGLTFTKDPFDRERYEDLRDLLSEML
                     NQASDLDSEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYAKFVFECKLLDGQFQEN
                     QEIADLQFFAIDPLPNLSEKRITKEQIEILWQVYQGQREQYLD"
     gene            24276..24980
                     /locus_tag="VQU19_000480"
     CDS             24276..24980
                     /locus_tag="VQU19_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HET2479785.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            25199..26572
                     /gene="ftsA"
                     /locus_tag="VQU19_000481"
     CDS             25199..26572
                     /gene="ftsA"
                     /locus_tag="VQU19_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HET2479786.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENIIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVESVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            26589..27848
                     /gene="ftsZ"
                     /locus_tag="VQU19_000482"
     CDS             26589..27848
                     /gene="ftsZ"
                     /locus_tag="VQU19_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HET2479787.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            27853..28524
                     /locus_tag="VQU19_000483"
     CDS             27853..28524
                     /locus_tag="VQU19_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HET2479788.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKATQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            28534..29073
                     /locus_tag="VQU19_000484"
     CDS             28534..29073
                     /locus_tag="VQU19_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HET2479789.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            29073..29336
                     /locus_tag="VQU19_000485"
     CDS             29073..29336
                     /locus_tag="VQU19_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HET2479790.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            29333..30017
                     /locus_tag="VQU19_000486"
                     /pseudo
     CDS             29333..30017
                     /locus_tag="VQU19_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
     gene            30026..30814
                     /gene="divIVA"
                     /locus_tag="VQU19_000487"
     CDS             30026..30814
                     /gene="divIVA"
                     /locus_tag="VQU19_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HET2479791.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVETPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            31162..33954
                     /locus_tag="VQU19_000488"
     CDS             31162..33954
                     /locus_tag="VQU19_000488"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HET2479792.1"
                     /translation="MKLKDTLNLGKTEFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     QGKPHFTLHDGPPYANGNIHVGHAMNKISKDIIVRSKSMSGFYAPFIPGWDTHGLPIE
                     QVLSKQGVKRKEMDLVEYLKLCREYALSQVDKQREDFKRLGVSGDWENPYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGEARKFVVAAELLTSLSEK
                     FGWADVQVLETYRGQELNHIVTEHPWDTAVEELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANNLEVAVTVDERGIMMKNAGPEFEGQFYEKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDEIEKVKFHSEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMVAETIEHVAQLFEEHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVVVNRPELTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFALDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDTVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYANFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFEAEDFVQLSELPEVQTFANQEEILD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SELTIAEEPAPEAALSFEDVVFTVERAAGEVCDRCRRIDPTTAERSYHAVICDHCASI
                     VEENFADAVAEGFEEK"
     gene            34364..34726
                     /locus_tag="VQU19_000489"
     CDS             34364..34726
                     /locus_tag="VQU19_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2479793.1"
                     /translation="MKSSGIVGLVGGILLLICPFVLLGTAVNTAATTLNGGATAGAFS
                     GVALLLNALKIANLVLGIIAIVYYKGDKHVGAAPSVLMIVSGEVSLIPFLGWVGGILA
                     IIGGSLFLATLKKFKSEE"
     gene            35261..35953
                     /locus_tag="VQU19_000490"
     CDS             35261..35953
                     /locus_tag="VQU19_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HET2479794.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIEFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            36006..38417
                     /locus_tag="VQU19_000491"
     CDS             36006..38417
                     /locus_tag="VQU19_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HET2479795.1"
                     /translation="MIRNKKQDYVLAYKQPASTTYMGWEEEALPIGNGSLGAKVFGLI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALATTSYVYKGTRFE
                     RKAFASFPDDLLIQCFTKEGLETLDFTIELSLTCDLASDGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEADVDASTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLETVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYSGNLFSY
                     KGQEYIEAARAILNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKTSTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            38667..39368
                     /locus_tag="VQU19_000492"
     CDS             38667..39368
                     /locus_tag="VQU19_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2479796.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIQMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            39370..42070
                     /locus_tag="VQU19_000493"
                     /pseudo
     CDS             39370..42070
                     /locus_tag="VQU19_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
     gene            complement(42166..42657)
                     /gene="tpx"
                     /locus_tag="VQU19_000494"
     CDS             complement(42166..42657)
                     /gene="tpx"
                     /locus_tag="VQU19_000494"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HET2479797.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(42780..43709)
                     /gene="psaA"
                     /locus_tag="VQU19_000495"
     CDS             complement(42780..43709)
                     /gene="psaA"
                     /locus_tag="VQU19_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HET2479798.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(43741..44589)
                     /locus_tag="VQU19_000496"
     CDS             complement(43741..44589)
                     /locus_tag="VQU19_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HET2479799.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(44586..45308)
                     /locus_tag="VQU19_000497"
     CDS             complement(44586..45308)
                     /locus_tag="VQU19_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HET2479800.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
BASE COUNT        13818 a         8141 c         9963 g        13480 t
ORIGIN      
        1 ttagaaaaac gaagtgagca gcttataaat tcaagtcccc aaatagattc atactagtat
       61 cttttgcaaa aaataaaggg cgacttcctt catgaatatc aatttcatct ataaggaagg
      121 tagctaattg aactaactta tttattctgt ttgtcgctag aaaaatcaga cctccttgtg
      181 aagattgagg agatactgaa tgaaaatcaa agaagaaact agcaagctag tagcagattg
      241 cccaaaacac cgccttgagg ttgtagataa gactgaccta tataatccaa ggtgaagcga
      301 ctgtggtttg aagagatttt caaagagtat aggctagaga gtagtgtttt tatgtccttc
      361 tagtagaaaa tgctagacag aagaatgggg aacttggata ggaaaaatag attgagaaag
      421 gaggttagaa gagatgatta ttacaaaaat tagccattta ggaacttatg tgggagtaaa
      481 tccacatttt gcaacattaa tagattttct agaaaaaaca ggactagaaa atttaacaga
      541 aggttcgatt gctatcgatg gtaatcgatt gtttgggaat tgctttactt atctagcaga
      601 tggtcaagca ggggctttct ttgaaacaca ccaaaaatat ttggatattc atttagtttt
      661 ggaaaacgaa gaagccatgg ctgttacatc gccggaaaat gtaagcgtta cccaagaata
      721 tgatgaagag aaagatattg aattatacac agggaaagtg gaacagttgg ttcagttgag
      781 agctggcgaa tgcctcatca cttttccaga agatttacat caacccaagg ttcgtataaa
      841 tgatgaacct gtgaaaaaag ttgtctttaa agttgcgatt tcttaatgta gaaagagaag
      901 aacgatgaaa aaaatgagaa agtttttatg tctagctgga attgcgctag cggctgttgc
      961 cttggtagct tgttcaggaa aaaaagaagc tacaactagt actgaaccac caacagaatt
     1021 atctggtgag attacaatgt ggcactcctt tactcaagga ccccgtttag aaagtattca
     1081 aaaatcagca gatgctttca tgcaaaagca tccaaaaacg aaaatcaaga ttgaaacatt
     1141 ttcttggaat gacttctata ctaaatggac tacaggttta gcaaatggaa atgtgccaga
     1201 tatcagtaca gctcttccta accaagtaat ggaaatggtc aactcagatg ctttggttcc
     1261 gctaaatgat tctatcaagc gtattggaca agataaattt aacgaaactg ccttaaatga
     1321 agcaaaaatc ggagatgatt actactctgt tcctctttat tcacatgcac aagtcatgtg
     1381 ggttagaaca gatttgttaa aagaacataa tattgaggtt cctaaaactt gggatcaact
     1441 ctatgaagct tctaaaaaat tgaaagaagc tggagtttat ggcttgtctg ttccgtttgg
     1501 aacaaatgac ttaatggcaa cacgtttctt gaacttctac gtacgtagtg gtggaggaag
     1561 cctcttaaca aaagatctta aagcagactt gacaagccaa cttgctcaag atggtattaa
     1621 atactgggtt aaattgtata aagaaatctc acctcaagat tctttgaact ttaatgtcct
     1681 tcaacaagct accttgttct atcaaggaaa aacagcattt gactttaact ctggcttcca
     1741 tatcggagga attaatgcca acagtcctca attgattgat tcgattgatg cttatcctat
     1801 tccaaaaatc aaagagtctg ataaagacca aggaattgaa acctcaaaca ttccaatggt
     1861 tgtttggaaa aattcaaaac atccagaagt tgctaaagca ttcttagaag cactttataa
     1921 tgaagaagac tacgttaaat tccttgattc aactccagta ggtatgttgc caactattaa
     1981 ggggattagc gattctgcag cctataaaga aaatgaaact cgtaagaagt ttaaacatgc
     2041 tgaagaagta attactgaag ctgttaaaaa aggtactgct attggttatg aaaatggacc
     2101 aagtgtacaa gctggtatgt tgactaacca acacattatt gaacaaatgt tccaagatat
     2161 cattacaaat ggaacagatc ctatgaaagc agcaaaagaa gcagaaaaac aattaaacga
     2221 tttatttgag gctgttcagt agatgtaaaa gactagaaaa taggtgggct agtgagctga
     2281 aaagctctag cccaatcttg taaaagaagg gagaaggaga atggttaaag aacgtaattt
     2341 aactcgctgg atatttgttt tgccagctat gattatcgta ggattactct ttgtttatcc
     2401 gtttttctcg agtatttttt atagctttac caataagcat ttgattatgc ctaattataa
     2461 atttgttggt ttggctaact ataaagctgt gctatcagat cccaacttct ttaatgcgtt
     2521 ctttaattca attaagtgga ccgttttctc attagttggt caagttttag tagggtttgt
     2581 attggcttta gctcttcaca gagtacgcca cttcaagaaa ttatatagga ccttattgat
     2641 tgttccttgg gcatttccta ccatcgttat tgccttttct tggcagtgga ttctaaacgg
     2701 ggtttatggc tacttaccta atctaatcgt aaaattaggt ttaatggaac atacacctgc
     2761 atttttgaca gatagtacat gggcattcct atgtttggtg tttatcaaca tttggtttgg
     2821 agcaccaatg attatggtta atgtgctttc agctttgcaa acagtaccag aagaacaatt
     2881 tgaggctgct aagatagatg gtgcttcaag ttggcaggtg ttcaagttta tcgtctttcc
     2941 acatattaaa gtggttgtag gacttctagt tgttttgaga actgtatgga tctttaataa
     3001 ctttgacatt atctacctca ttactggtgg tggaccagcc aatgctacaa cgacgcttcc
     3061 aatttttgct tacaacctgg gctggggaac taaattgttg ggtcgtgctt cagcagttac
     3121 agtattgctc tttatcttct tggtggcgat ttgctttatc tactttgcta tcatcagtaa
     3181 gtgggaaaag gagggtagaa aataatgaag aagaaatcca gtatttattt agatattctc
     3241 tcacatgtac ttttagttgg tgcgaccatc gttgcaattt tcccattggt atggattatc
     3301 atatcttctg tcaaagggaa aggggaatta actcagtatc caacacgatt ttggcctgaa
     3361 cagtttacat tagattattt cactcatgtt atcaacgatt tgcacttcat tgataacatt
     3421 cgaaacagtt taatcattgc cttggctaca accctcattg cgattattat ttctgctatg
     3481 gcagcctatg gtattgttcg attctttcct aaattgggag caatcatgtc gagactactc
     3541 gtcattacct acattttccc accaattttg ttagcaattc cctattcaat tgccattgct
     3601 aaagttgggt taacaaatag tttatttggc ttgatgatgg tttatctatc ttttagtgtt
     3661 ccatatgcag tttggctctt agttggattt ttccaaacag ttccaattgg aattgaagaa
     3721 gcggctagaa ttgatggtgc aaataaattt gttacgtttt ataaagttgt gctaccgatt
     3781 gtagcaccag gtattgtagc aacagctatt tatacattta tcaatgcttg gaatgaattc
     3841 ctgtatgcct tgattttgat taacaataca ggaaagatga cagtagcagt agcccttcgt
     3901 tcacttaatg gttcagaaat actagactgg ggagatatga tggcagcgtc tgttattgta
     3961 gttcttccat caattatttt cttctctatc atccaaaata agattgcaag tggattatca
     4021 gaaggatctg tgaagtagac gaaagaagga aaaaaatgaa taaaagaggt ctttattcaa
     4081 aactaggaat ttctgttgta ggcattagtc ttttaatggg agtccccact ttgattcatg
     4141 cgaatgaatt aaactatggt caactgtcca tatctcctat ttttcaagga ggctcatatc
     4201 aactgaacaa taagagtata gatatcagcc ctttgttatt agataaattg tctggagaga
     4261 gtcagacagt agtaatgaaa tttaaagcag atgaaccaaa ctctcttcaa gctttgtttg
     4321 gcctatctaa tagtaaagca ggctttaaaa ataattactt ttcaattttc atgagagatt
     4381 ctggtgagat aggtgtagaa ataagagacg cccaaaaggg aataaattat ttattttcca
     4441 gaccagcttc attatgggga aaacataaag gacaggcagt tgaaaataca ctagtatttg
     4501 tatctgattc taaagataaa acatacacaa tgtatgttaa tggaatagaa gtgttctctg
     4561 aaacagttga tacatttttg ccaatttcaa atataaatgg tatagataag gcaacactag
     4621 gagctgttaa tcgtgaaggc aaggaacatt acctcgcaaa aagaagtatt gatgaaatca
     4681 gtctatttaa caaagcaatt agtgatcagg aagtttcaaa tattcccttg tcaaatccat
     4741 ttcagttaat tttccaatca ggagattcta ctcaagctaa ctattttaga ataccgacac
     4801 tatatacatt aagtagtgga agagttctat caagtattga tgcacgttat ggtgggactc
     4861 atgattctaa aagtaagatt aatattgcca cttcttatag tgatgataat gggaaaacgt
     4921 ggagtgagcc aatttttgct atgaagttta atgactatga ggagcagtta gtttactggc
     4981 cacgagataa taaattaaag aatagtcaaa ttagtggaag tgcttcattc atagattcat
     5041 ccattgttga agataaaaaa tctgggaaaa cgatattact agctgatgtt atgcctgcgg
     5101 gtattggaaa taataatgca aataaagccg actcaggttt taaagaaata aatggtcatt
     5161 attatttaaa actaaagaag aatggagata acgatttccg ttatacagtt agagaaaatg
     5221 gtgtcgttta tgatgaaaca actaataaac ctacaaatta tactataaat gataagtatg
     5281 aagttttgga gggaggaaag tctttaacag tcgaacaata ttcggttgat tttgatagtg
     5341 gctctttaag agaaaggcat aatggaaaac aggttcctat gaatgttttc tacaaagatt
     5401 cgttatttaa agtgactcct actaattata tagcaatgac aactagtcag aatagagaag
     5461 agagttggga acaatttaag ttgttgcctc cgttcttagg agaaaaacat aatggaactt
     5521 acttgtgtcc tggacaaggt ttagcattaa aatcaagtaa cagattgatt tttgcaacat
     5581 atactagtgg agaactaacc tatctcattt ctgatgatag tggtcaaaca tggaagaaat
     5641 cctcagcttc aattccgttt aaaaatgcaa cagcagaagc acaaatggtt gaactgagag
     5701 atggtgtgat tagaacattc tttagaacca ctacaggtaa gatagcttat atgactagta
     5761 gagattctgg agaaacatgg tcggaagttt cgtatattga tggaatccaa caaacttcat
     5821 atggcacaca agtatctgca attaaatact ctcaattaat tgatggaaaa gaagcagtca
     5881 ttttgagtac accaaattct agaagtggcc gtaagggagg tcaattagtt gtcggtttag
     5941 tcaataaaga agatgatagt attgattgga aataccacta tgatattgat ttgccttcgt
     6001 atggttatgc ctattctgcg attacagaat tgccaaatca tcacataggt gtactgtttg
     6061 aaaaatatga ttcgtggtcg agaaatgaat tgcatttaag caatgtagtt cagtatatag
     6121 atttggaaat taatgattta acaaaataaa ggagaaaaac atggttaaat acggtgttgt
     6181 tggagcaggg tattttggag ctgaattggc tcgctacatg caaaagaatg atggagcaga
     6241 gattactctt ctctatgatc cagataatgc agaggcgatt gcagaagaat tgggagcaaa
     6301 agtagcaagt tccttagatg agttggtttc tagcgatgaa gtagattgtg ttatcgtcgc
     6361 aactccaaat aatcttcata aggaaccggt tattaaggct gcacagcatg gtaaaaatgt
     6421 tttctgtgaa aaaccaattg cgctttctta tcaagattgt cgcgagatgg tagatgcgtg
     6481 taaagaaaac aatgtaacct ttatggcagg acatattatg aatttcttta atggtgttca
     6541 tcatgcaaaa gaactcatta atcaaggagt tatcggagac gttctatatt gtcatacagc
     6601 tcgtaatggt tgggaagaac aacaaccgtc agtgtcatgg aaaaaaattc gtgaaaaatc
     6661 aggtggtcac ttgtatcacc acatccatga attggattgc gttcaattcc ttatgggggg
     6721 catgcctgaa actgtaacca tgacaggtgg aaatgtggcc catgaaggtg aacatttcgg
     6781 tgatgaagat gatatgattt ttgtcaatat ggaattttct aataagcgtt ttgccttgtt
     6841 agaatggggt tcagcttatc gttggggtga acattatgtc ttaatccaag gaagcaaagg
     6901 tgccatccgc ttagacttat tcaactgtaa aggaactctt aagctagatg ggcaagaaag
     6961 ctatttcttg attcacgaat cgcaagaaga agatgatgat cggactcgta tctatcatag
     7021 tacagagatg gatggagcaa ttgcttatgg taaaccaggt aaacgtactc cattatggct
     7081 atcatctgtc attgataaag aaatgcgcta tctgcatgag attatggaag gagctccagt
     7141 atcagaagaa tttgcaaaac ttttgacagg tgaagctgcc ctagaagcaa ttgctactgc
     7201 agatgcttgt acccagtcta tgtttgaaga tcgcaaagta aaattgtcag aaattgtaaa
     7261 ataaattttg gtattctcct atttataggt cgacttgctc ctctgaaagt acttttagag
     7321 gagctgtttg actttgctag tttttgaaac tgaaatctat tatactacaa actattgaaa
     7381 gcgttttaat tttaaggtat aataatctca tagaaataaa gaaaaggagg aaagaggatg
     7441 ccacagatta gcaaagaagc cttgattgag caaatcaaag atggaatcat cgtttcttgt
     7501 caggctcttc ctcatgaacc gctttataca gaagcgggag gggtgattcc cttgctggtc
     7561 aaagcggctg agcaaggtgg agcagtcggt atccgagcaa acagtgttcg cgatatcaag
     7621 gaaattaagg aagtcactaa acttccaatc attgggatta tcaaacgtga ttatccacct
     7681 caggaaccct tcatcacggc tactatgaaa gaagttgatg aattggcaga actggacatc
     7741 gaggtgattg ctctggattg taccaagcgt gaacgctacg atggtttgga aattcaagag
     7801 ttcattcgtc aggttaagga gaaatatcct aatcagcttt tgatggctga tactagtatc
     7861 ttcgaagaag ggctagcagc tgtagaagca ggaattgact ttgtcggaac aaccttatca
     7921 ggctacacat cctacagtcc aaaagtagac ggtccagatt ttgaattgat taagaaactc
     7981 tgtgatgccg gtgtagatgt cattgcagaa ggaaaaattc atacaccaga acaagccaaa
     8041 caaatccttg aatatggagt gcgaggcatc gttgttggtg gcgccattac tagaccaaaa
     8101 gagattacag aacgcttcgt tgctagtctt aaataagatg tgagggggag ttttatgttt
     8161 aaagttttac aaaaagttgg aaaagctttt atgttaccta tagctatact tcctgcagca
     8221 ggtctacttt tggggattgg tggtgcactt tcaaacccaa ccacgatagc aacttatcca
     8281 atactagaca atagtatttt tcaatcaata ttccaagtaa tgagctctgc aggagaggtt
     8341 gtattcagta atttgtcact acttctctgt gtgggattat gtattggctt agcgaaacga
     8401 gataaaggaa ccgctgcgtt agcaggagta actggttact tagttatgac tgcaacgatc
     8461 aaagctttag taaaactttt tatggcagaa ggatctgcaa ttgatactgg agttattgga
     8521 gcattagttg tcggaatagt tgccgtatat ttgcacaacc gatataacaa tattcaatta
     8581 ccttccgctt taggattctt tggaggttca cgcttcgttc ctattgttac atcgttctct
     8641 tctatcttga ttggctttgt cttctttgtt atttggccac ctttccaaca acttcttgtt
     8701 tctacaggtg gatatatttc tcaggcgggt ccaattggaa cttttctata tggattttta
     8761 atgagacttt ctggagcagt aggcttacat catataattt accctatgtt ttggtatact
     8821 gaacttggtg gtgttgaaac tgttgcagga caaacagtgg ttggagctca aaaaatattt
     8881 tttgctcaat tagccgattt ggcccattct ggattattta cagaaggaac aaggtttttt
     8941 gcaggtcgtt tctcaacaat gatgttcggt ttaccggctg cctgtttagc gatgtaccat
     9001 agtgttccta aaaatcgtcg taaaaaatac gcgggtttgt ttttgggagt tgctttaaca
     9061 tcttttatta ccggtattac agaaccaatt gaatttatgt ttctattcgt tagtccggtt
     9121 ctatatgttg ttcacgcatt ccttgatggt gttagcttct ttattgcaga cgtcttaaat
     9181 atttcaatag gaaacacatt ttcaggaggt gtaatcgatt tcactttatt tggaattttg
     9241 caggggaacg ctaagacgaa ttgggttctt cagattccat ttggacttat ttggagtgtt
     9301 ttgtattata ttatttttag atggttcatt actcaattca acgttctaac gccagggcga
     9361 ggagaagaag tagattctaa agaaatttct gaatccgcag attcaacttc aaatactgca
     9421 gattatttaa aacaggatag cctacaaatt atcagagcct tgggtggatc aaataatata
     9481 gaagatgtag atgcttgtgt gacacgttta cgtgtagctg taaaagaagt taatcaagtt
     9541 gataaagcac ttttaaaaca aattggtgca gttgatgtct tagaagtgaa gggtggcatt
     9601 caagcaatat atggagcaaa agcaatctta tataaaaata gtattaatga aattttaggt
     9661 gtagatgatt aagtacttac tgacttaata aaaaacagag gagagtgatg gatgagtagg
     9721 atgaaatgaa atcgcataca agaaataaag aactcattat ccaagttgga tacgcttatt
     9781 acataggaga atacaaatga aatttagaaa attagcttgt acagtacttg cgggtgctgc
     9841 ggttcttggt cttgctgctt gtggcaattc tggcggaagt aaagatgctg ccaaatcagg
     9901 tggtgacggt gccaaaacag aaatcacttg gtgggcattc ccagtattta cccaagaaaa
     9961 aactggtgac ggtgttggaa cttatgaaaa atcaatcatc gaagcgtttg aaaaagcaaa
    10021 cccagatata aaagtgaaat tggaaaccat cgacttcaag tcaggtcctg aaaaaatcac
    10081 aacagccatc gaagcaggaa cagctccaga cgtactcttt gatgcaccag gacgtatcat
    10141 ccaatacggt aaaaacggta aattggctga gttgaacgac ctcttcacag atgaatttgt
    10201 taaagatgtc aacaatgaaa acatcgtaca agcaagtaaa gctggagaca aggcttatat
    10261 gtatccgatt agttctgccc cattctacat ggcaatgaac aagaaaatgt tagaagatgc
    10321 tggagtagca aaccttgtaa aagaaggttg gacaactgat gattttgaaa aagtattgaa
    10381 agcacttaaa gacaagggtt acacaccagg ttcattgttc agttctggtc aagggggaga
    10441 ccaaggaaca cgtgccttta tctctaacct ttatagcggt tctgtaacag atgaaaaagt
    10501 tagcaaatat acaactgatg atcctaaatt cgtcaaaggt cttgaaaaag caactagctg
    10561 gattaaagac aatttgatca ataatggttc acaatttgac ggtggggcag atatccaaaa
    10621 ctttgccaac ggtcaaacat cttacacaat cctttgggca ccagctcaaa atggtatcca
    10681 agctaaactt ttagaagcaa gtaaggtaga agtggtagaa gtaccattcc catcagacga
    10741 aggtaagcca gctcttgaat accttgtaaa cggatttgca gtattcaaca ataaagacga
    10801 caagaaagtc gctgcatcta agaaattcat ccagtttatc gcagatgaca aagagtgggg
    10861 acctaaagac gtagttcgta caggtgcttt cccagtccgt acttcatttg gaaaacttta
    10921 tgaagacaaa cgcatggaaa caatcagcgg ctggactcaa tactactcac catactacaa
    10981 cactattgat ggttttgctg aaatgagaac actttggttc ccaatgttgc aatctgtatc
    11041 aaatggtgac gaaaaaccag cggatgcttt gaaagccttc actgaaaaag caaacgaaac
    11101 aatcaaaaaa gctatgaaac aatagtcctt agttattcta taaaaagtag ttttttaaag
    11161 aacctaagag tgtatacccc cttttccctc tacacagata gtgtaagaaa agggggcttt
    11221 tgtttaaaat gtaagaaact gtcacgaaat taaaatgaag ttcttacata agcgaatcat
    11281 aaaaaatttc attttgattt taaaacagtt caagaaagtc aaaaaattat tctatttgaa
    11341 agagaggtgc cgactgtgaa agtcaataaa atccgtatgc gggaaacagt gatttcctac
    11401 gctttcctag caccagtatt attcttcttt gtcatctttg tgttggctcc gatggtgatg
    11461 ggcttcatta caagtttctt taactactca atgactaaat ttgagtttgt aggcttggat
    11521 aactatatcc gtatgtttaa agatcctgtc tttacaaaat ctctgattaa cacagttatt
    11581 ttggttattg gatctgtacc agttgttgtt ctattctcac tctttgtagc atctcagacc
    11641 tatcatcaaa atgtcattgc cagatccttc taccgtttcg tcttcttcct tcctgttgta
    11701 acgggtagtg ttgccgtgac agttgtttgg aaatggattt atgacccact atcagggatt
    11761 ctaaactttg tccttaagtc cagccacatc atcagccaaa acatttcttg gttgggagat
    11821 aaaaactggg cattgatggc gattatgatt attctcttga ccacttcagt tggtcagccc
    11881 atcatccttt atatcgctgc catggggaat attgacaatt cactggttga agcggcgcgt
    11941 gttgatggtg caactgagtt tcaagttttt tggaagatta aatggccaag ccttcttcca
    12001 acaactcttt atattgcaat catcacaaca attaactcat tccagtgttt cgccttgatt
    12061 cagcttttga catctggtgg tccaaactac tcaacaagta ccttgatgta ctacctttac
    12121 gaaaaagcct tccaattgac agaatacggc tatgccaaca caattggtgt cttcttggca
    12181 gtcatgattg ctatcgtaag ctttgttcaa tttaaagtac ttggaaacga cgtagaatac
    12241 taaagaaagg agacagctat gcaatctaca gaaaaaaaac cattaacagc ctttactgtt
    12301 atttcaacaa tcattttgct cttgttgact gtgctgttca tctttccatt ctactggatt
    12361 ttgacagggg cattcaaatc acaacctgat acaattgtta ttcctcctca gtggttccct
    12421 aaaatgccaa ccatggaaaa cttccaacaa ctcatggtgc agaaccctgc cttgcaatgg
    12481 atgtggaact cagtatttat ctcattggta accatgttct tagtttgtgc aacctcatct
    12541 ctagcaggtt atgtattggc taaaaaacgt ttctatggtc aacgcattct atttgctatc
    12601 tttatcgctg ctatggcgct tccaaaacaa gttgtccttg taccattggt acgtatcgtc
    12661 aacttcatgg gaatccacga tactctctgg gcagttatct tgcctttgat tggatggcca
    12721 ttcggtgtct tcctcatgaa acaatttagt gaaaatattc ctacagagtt gcttgaatca
    12781 gctaaaatcg acggttgtgg tgagattcgt accttctgga gtgtagcctt cccgattgtg
    12841 aaaccagggt ttgcagccct tgcaatcttt accttcatca atacttggaa tgactacttc
    12901 atgcagttgg taatgttgac ttcacgtaac aatttgacca tctcacttgg ggttgcgacc
    12961 atgcaggctg aaatggcaac caactatggt ttgattatgg caggagctgc ccttgctgct
    13021 gttccaatcg tcacagtctt ccttgtcttc caaaaatcct tcacacaggg tattactatg
    13081 ggagcggtca aaggataata ctctgcgaaa atcgaatgca aactacgtca gcttcacctt
    13141 gccatactta agtattgcct gcggttagct tcctagtttg ttcttcaatt ttcattgagt
    13201 ataggaaaat caatctatca agatacagaa gtatatttta tagatttaga gaatatagaa
    13261 gttataagtg tctacaaaat ggagggtatg cagttacttt atgaagtttt gtcagacact
    13321 tatcaactta agaatgattt tagttaatta tcagaaacga aggaaagagt atgatttttg
    13381 acgatttgaa aaacatcacc ttttacaaag ggattcatcc caatttagac aaagctatcg
    13441 actacctcta ccaacatcgt aaagattcat tcgaattagg aaagtatgag attgatggag
    13501 ataaggtctt tctagttgtt caggaaaatg tcctcaatca agttgagaat aatcaatttg
    13561 aacaccataa gaactatgca gatttgcatt tgctgataga agggcatgaa tattcgagct
    13621 acggttcacg tatcaaagac gaggcagtag cattcgacga agcgactgac attggctttg
    13681 ttcattgtca tgaacactac ccactcttgt tgggttatca taattttgcg attttcttcc
    13741 caggtgagcc acatcagcca actggctatg caggtatgga agaaaaggtt cgaaaatatc
    13801 tctttaaaat tttgattgat taaaaatagg atgaattgtt tttttgtaaa gctttgacaa
    13861 tactctacca tgaaattgat ctttatgagg tagagaaatg agaataaaat atttaaaaat
    13921 tggtatcttc taagcatgct gcaagagcta gtttcttaga tggacaggaa attacagttg
    13981 atgagatgtc ctggataatt aatggcattg tgaatgcatt gattggtaga tacataaaat
    14041 taggtactta tgcagctaag tatggtattg gtatagcacg ctcgatctta agtagggcag
    14101 ctgcaactgc agcagcaaga gtaggattac tgaccaagat ttctggatgg attttacgag
    14161 tagctgtgaa tgtagctgat gtatatggta atttcgccaa caatattgct gcagcttggg
    14221 atgcatatga taaaattcct aacaatggtc gtataaactt ttaaaatacg agaatgaaag
    14281 cactttgtat ttttttattg aatatgttag cttggacagt gcttgcaatg ataattcgtg
    14341 gagggctaga tggatttgat aggcatactt ggagtactat tttaattgct tcgctgttcg
    14401 gggtatatga ttataagccc atagataaaa atagaaaaaa gtccaaaaga aaaaagaaaa
    14461 aatagatttg ttcatggtag ggacttatga aagctttact gacaaaaaag aaaacagttt
    14521 acaaagaaaa atgatggagg agcaaacatg gcacaaaaag gagtaagcct tatcaaggca
    14581 gcatttgata cagataactt tctcatgcgt tttagtgaga aggtcttgga catcgtgaca
    14641 gccaatcttc tttttgtcgt ctcttgttta cccatcgtga cgattggagt ggctaaaatc
    14701 agcctctacg agaccatgtt cgaagttaag aagagcagac gggtgcctgt ttttaaaatc
    14761 tatctaagat ctttcaagca aaatctgaaa ctaggtcttc agctgggttt aatggagtta
    14821 ggaattgtgt ttcttaccct ttcagatctc tatcttttct ggggtcaaac agctctgccc
    14881 ttccaattgc tgaaagccat ttgtttaggt attctgattt ttcttactat cgtgatgctg
    14941 gctagttacc ctatcgcggc acgttatgac ctatcttgga aagaaattct tcaaaaagga
    15001 ttgatgttgg ctagttttaa ctttccttgg ttcttcctca tgttagccat tcttgtcctc
    15061 attgtgatgg ttctttatct gtccgccttc agtctactct taggtggctc agtcttccta
    15121 ctttttgggt ttggactatt ggtctttatc cagactggat tgatggagaa aattttcgca
    15181 aaataccaat aggagcttta tttctgaaac tactttcaaa ggctccaaac gctattctat
    15241 aagcgagaaa ctaaaatcta agtgtctata agatattgaa agccttttcg gtaaagtgta
    15301 tactaaagaa gtaaagaaaa atctgcttta gcagaaaata aaaataatag gagaaaatct
    15361 atgtcagatt tgaaaaaata cgaaggtgtc attccagcct tctacgcatg ttatgatgag
    15421 caaggagaag taagtccaga gcgtacgcgt gccttggttc aatacttcat tgataaaggt
    15481 gttcaaggtc tttatgtcaa tggttcttct ggtgaatgta tctaccaaag cgttgaagat
    15541 cgcaagttga ttttggaaga agtcatggcg gtagctaaag gtaaattgac cattattgcc
    15601 catgttgcct gcaacaatac taaagacagt atggaacttg ctcgccatgc tgaaagcttg
    15661 ggagtagatg ctattgcaac gattccacca atttatttcc gcttgccaga atactcagtt
    15721 gccaaatact ggaacgatat cagttctgca gctccaaaca cagactacgt gatttacaac
    15781 attcctcaat tggcaggggt tgctttgact ccaagccttt acacagaaat gttgaaaaat
    15841 cctcgtgtta tcggtgtgaa gaactcttct atgccagttc aagatatcca aacctttgtc
    15901 agccttggtg gggaagacca tatcgtcttt aacggtccag atgaacagtt cctaggtggt
    15961 cgcctcatgg gtgccaaagc tggtatcggt ggtacttatg gtgctatgcc agaactcttc
    16021 ttgaaactca accaattgat tgcggataaa gatttagaaa cagcgcgtga gttacagtat
    16081 gctatcaacg ctatcattgg taaattgact gctacacatg gaaatatgta cggtgtcatc
    16141 aaagaagttt tgaagatcaa tgaaggcttg aatattggtt ctgttcgttc accattgaca
    16201 ccagtgactg aagaagatcg tccagttgta gaagcggctg ctgccttgat tcgtgaaacc
    16261 aaggagagct tcctctaatc taaaaggagg tatttatgac atactacgtt gcaattgata
    16321 tcggtggaac caacatcaag tatggtttgg ttgatcaaga ggggcaactt cttgaatcgc
    16381 atgaaatgcc aactgaggcg cataagggtg gacctcatat cttacaaaag accaaagata
    16441 tcgtagctag ttatttagaa aaaggcccag tagcaggtgt tgccatatct tctgctggga
    16501 tggtggatcc ggataagggt gagattttct atgctgggcc gcaaatccct aactacgcag
    16561 gcacccagtt caaaaaggaa atcgaagaaa gctttactat tccttgtgag attgaaaatg
    16621 atgtcaactg tgcaggtctt gctgaggcag tatctggttc aggcaaggga gcaagtgtga
    16681 cactttgctt gaccattgga accggtatcg gtggttgctt gattatggat aggaaagtct
    16741 tccatggttt tagcaattca gcctgtgaag tcgggtatat gcatatgcag gatggagctt
    16801 ttcaagactt ggcttctaca acagctttag tgaaatatgt agctgaagcc catggagaag
    16861 atgttgatca gtggaatggc cgtagaattt tcaaagaagc cactgaagga aacaaaatct
    16921 gcatggaagg tattgaccgt atggttgact atctaggaaa aggtctggca aatatttgct
    16981 acgttgccaa tccagaagtg gttattcttg gtggtggtat catggggcaa gaggctatcc
    17041 tcaaacctaa gatccgcaca gccttgaaag aggctttggt accaagttta gcagaaaaaa
    17101 cacgattaga atttgcccat caccaaaata cagcagggat gttgggtgca tattatcatt
    17161 ttaagacaaa acaatcctag tttggctcag ccaaactagg attttcttac acgtttttgt
    17221 ctacgatagc cgttgagttt tttattttcc cagtagctat taaagatttt ttccttgctt
    17281 tcgcgattga tttccaaaaa gtaggcataa atcaaatcga taaagaagag cataggaagt
    17341 tgagcggata ttcgttggat ataggagggt tggctgtggg tggctacaag aacagtctct
    17401 gtataggtct ggctatcttt attgggaaca cttgtaaaga gtacagtctt tgcccccatc
    17461 tccttggcat ctaatagact atctaaaata gaaggagttg agcctgaaag tgagaagccc
    17521 agtactagac aattttcatc catgatgctg gttgtccagg caaagccgtc ttggtctgtc
    17581 aaagcttcgc agaccacacc tagtcgcata aaacgtaatt tcatttcacg ggcgacgagg
    17641 ccagaactcc ctgttccaaa gaagtagata cgctcagcat cttcgattag ctgggcaatt
    17701 cgctctagtt ggatttcgtc aatcaagtct tgtgtttgtt ccctcatatt gctataactt
    17761 ctgaggactc gtttggtcag tggactgtgc ttggagactc ggttggcttg attttctgcc
    17821 tgatgttggt attggaaaat aaattctcgg tagccagtaa agccacactt tttagcaaag
    17881 cgggtcaaag cagcttgaga aatatgtaat ttttgggtga cttgttgaga agataaatca
    17941 tctgtaatcg tttcagcttg caaaaaatag cgagcgattt cttgctctag gtctgtcatt
    18001 tcttcaaaat gtgaatcaat gatagttgcg atatctggtt tgtccatagg gaaagctcct
    18061 ttacatgagt catactggaa gactagatca gggaatagtc acacttcatt ataacacata
    18121 atataaggat agataaataa aaacgcatct ctgttttaaa aacgaaaaaa tcgaaaaagc
    18181 ttctctcttt tccataattt tctactcaaa ttgtggtaca attaagagta agattttaag
    18241 ttagaaatga gactgatttg tatgagaaaa tttaacagcc attcgattcc gattcggctt
    18301 aatttattgt tttcaatcgt cattttactc tttatgacca ttattggtcg tttgttgtat
    18361 atgcaggttt tgaacaagga tttttacgaa aaaaagctag cctcagctag tcagaccaag
    18421 attacaagca gttcagcccg tggggaaatt tatgatgcta gtggaaaacc tttggtagaa
    18481 aatacgttaa agcaggttgt ttcctttacg cgtagcaata aaatgacggc tacagactta
    18541 aaagaaacag ctaaaaagtt actgacttat gtgagcatca gttctccaaa tttgacaaaa
    18601 cgccagctgg cggattacta tttggctgat cctgaaatct ataaaaaaac agtggaagct
    18661 ctcccaagcg agaaacgctt ggattcagat ggcaatcgtc tatccgaatc agaactgtat
    18721 aacaatgcgg tcgatagtgt ccaaacaagt caactaaact atacagagga tgaaaagaaa
    18781 gaaatctatc tttttagtca gttaaatgct gttggaaact ttgcgacagg aaccattgct
    18841 acagatcctc taaatgattc tcaggtggct gttattgcct ctatttcaaa ggagatgcct
    18901 ggcattagta tttctacttc ttgggataga aaggttttgg aaacttccct ttcttctata
    18961 gttgggagtg tatccagtga aaaagctggt ctcccagcgg aagaagcaga agcctatctt
    19021 aaaaaaggct attctctaaa tgaccgtgta ggaacctcct atttggaaaa gcaatatgaa
    19081 gagaccttac aaggaaaacg atcggtaaaa gaaatccatc tggataaata tggcaatatg
    19141 gaaagcgtgg atacaattga ggaaggtagt aagggaaaca atatcaaact gaccattgat
    19201 ttggccttcc aagatagcgt ggatgctttg ctgaaaagtt atttcaattc tgagctagaa
    19261 aatggtggag ccaagtattc tgaaggtgtc tatgcagtcg cccttaaccc aaaaacaggt
    19321 gcggttttgt ctatgtcagg gattaaacat gacttgaaaa cgggagagtt gacgcctgat
    19381 tccttgggaa cggtaaccaa tgtctttgtt ccaggttcgg ttgtcaaggc ggcgaccatc
    19441 agctcaggtt gggaaaatgg agtcttgtca ggaaaccaga ccttgacaga ccagtccatt
    19501 gtcttccaag gttcagctcc catcaattct tggtatactc aggcttacgg ttcattccct
    19561 atcacagcgg tccaagctct ggagtattca tcaaatacct atatggtcca aacagcctta
    19621 ggtcttatgg ggcaaaccta tcaacccaat atgtttgtcg gcaccagcaa tctagagtct
    19681 gctatggaga aactgcgttc aacctttggc gaatatggct tgggtactgc gacaggaatt
    19741 gacctaccag atgaatctac tggatttgtt cccaaagagt atagctttgc taattacatt
    19801 actaatgcct ttgggcagtt tgataactat acgccgatgc agttggctca gtatgtagca
    19861 actattgcaa ataatggtgt tcgtgtggct cctcgtattg ttgaaggcat ttatggtaat
    19921 aatgataagg gaggactggg tgacttgatt cagcaactgc aaccgacaga gataaataag
    19981 gtcaatatat ccgactccga tatgagcatc ttgcaccaag gtttttatca ggttgcccat
    20041 ggtactagtg gattgacaac tggacgtgcc ttttcaaatg gtgccttggt atccattagc
    20101 ggaaaaacag gtacagccga aagctatgtg gcagatggtc agcaagcaac caataccaat
    20161 gcggtggcct atgccccatc tgataatccc caaatcgctg tcgcagtggt ctttcctcat
    20221 aataccaatc taacaaatgg tgtaggacct tccattgcgc gtgacattat caatctgtat
    20281 caaaaatacc atccaatgaa ctagaaagga aattatgctt tatccaacac ctattgccaa
    20341 gttgattgac agttattcta agttaccagg tatcgggatt aagacggcta cgcgtctggc
    20401 cttttatacg attgggatgt ctgctgatga tgtcaatgaa tttgcaaaaa atctcctttc
    20461 tgctaagaga gaattgacat attgttctat ttgtggacgt ttgacagacg acgatccttg
    20521 ttctatctgt actgatccga ctcgtgacca gacaacaatt ttagttcttg aggatagtag
    20581 agatgtggca gccatggaaa atatccaaga ataccatgga ctctatcatg tcctgcatgg
    20641 cctcatttct cctatgaatg gtatcagtcc ggacgatatc aatctcaaga gccttatgac
    20701 tcgtcttatg gatagtgagg tttcagaagt gattgtggcg actaatgcta cagcggatgg
    20761 tgaagcgact tccatgtatc tttcacgttt gctcaagcca gctggtatca aggttacgcg
    20821 tctagcacga ggtctcgctg tgggagcgga cattgagtat gcggacgaag tgacactctt
    20881 acgagcgatt gaaaatcgga cagagttgta agtgtaggca aatttacgaa ctcccttcat
    20941 ttataaaaaa tcaaagaggc tgaaaatcgt tcctatcggc ctctttttgt atagtgtgat
    21001 gagtaggatc gggttcaagt tttaaaaaac caagcaaata tgatatacta aagagcgagt
    21061 attctagtag aattaggaca aataatatga aacaaacgat tattctttta tatggtggac
    21121 ggagtgcgga acgcgaagtc tctgtccttt cagctgagag tgtcatgcgt gcggtcaatt
    21181 acgaccgttt cacagtcaag actttcttta tcagtcagtc aggtgacttt atcaaaacac
    21241 aggaatttag tcatgctccg gggcaagaag accgtctcat gaccaatgaa accattgatt
    21301 gggataagaa agttgcacca agtgctatct acgaagaagg tgcagtggtc tttccagtcc
    21361 ttcacgggcc aatgggagaa gatggctctg ttcaaggatt cttggaagtt ttgaaaatgc
    21421 cttacgttgg ttgcaacatt ttgtcatcaa gtcttgccat ggataaaatc acgactaagc
    21481 gtgttctgga atctgctggt attgcccaag ttccttatgt ggctatcgtt gaaggcgatg
    21541 atgtgactgc taaaatcgct gaagtggaag aaaaattggc ttatccagtc ttcactaagc
    21601 cgtcaaacat ggggtctagt gtcggtattt ctaagtctga aaaccaagaa gaactccgtc
    21661 aagccttaaa acttgccttc cgatatgaca gccgtgtctt ggttgagcaa ggagtgaatg
    21721 cccgtgaaat tgaggttggc ctcttgggta actacgatgt caagagcacg ctacctggag
    21781 aagttgtcaa ggacgttgcc ttttatgact acgatgccaa gtatattgat aacaagatta
    21841 ctatggatat tcctgccaaa atcagtgatg atgtggtagc tgtcatgcgt caaaatgcag
    21901 aaacagcctt ccgtgccatt ggtggccttg gtctatctcg ttgcgatttc ttctatacag
    21961 ataagggaga gatttttctc aacgagctca ataccatgcc aggtttcacc cagtggtcta
    22021 tgtacccact actttgggac aatatgggga tcagctaccc agaactaatc gagcgtttgg
    22081 ttgaccttgc caaggaaagt tttgacaagc gcgaagcgca tttgatataa aatgaaagag
    22141 agggtagaag ccagaaccat cactgcaagg tgactagagt tctcggactt cagccctttt
    22201 taaaggagta gaaatgaaat taacaatcca tgaagttgcc caagttgttg gagccaaaaa
    22261 tgatatcagt atctttgagg acacccagtt agaaaaagct gagtttgata gtcgtttgat
    22321 tggaactgga gatttatttg tgcccctaaa aggtgtgcgt gacggtcatg actttatcga
    22381 aagagctttt gaaaatggtg cggcagcaac cctgtctgag aaagaggttg caaatcatcc
    22441 ctacattcta gtagatgatg ttttgactgc ctttcaacaa ctagctgcct actatcttga
    22501 aaaaacagct gttgatgtct ttgcggttac gggttcaaat ggcaagacaa cgactaagga
    22561 tatgttggcg catttactgt caacaagata caagacctac aaaacacaag gcaattacaa
    22621 taatgagatt ggccttcctt acacagttct ccacatgcct gaaggaacag aaaagttggt
    22681 cttggagatg gggcaggacc acttgggaga tattcatctc ttgtctgaat tggctcgtcc
    22741 aaaaacagcc atcgtgacct tggttggaga agctcatttg gcctttttca aagatcgttc
    22801 tgagattgct aaaggaaaaa tgcaaattgc agacggaatg gcttcaggtt ccttgctttt
    22861 agcgccggct gaccctatcg tagaggacta tttgccaact gataaaaagg tggttcgttt
    22921 tggtcaagga gcagagctgg aaattactga cttggttgag cgcaaagata gtctgacctt
    22981 caaggccaat ttcttagagc aagtccttga tttgccagta actggcaagt acaatgcgac
    23041 aaatgctatg attgcatcct atgttgcctt gcaagaagga gtttcagagg agcaaattcg
    23101 tttggccttc caacatcttg aattgacgcg taaccgtacc gagtggaaga aagcagccaa
    23161 tggagcagac atcttgtcag atgtttacaa tgccaatcca actgctatga agctgatttt
    23221 agagaccttc tctgccattc cagccaatga aggtggcaag aaaattgcag tgttggcgga
    23281 tatgaaggaa cttggtgtcc agtctgttca acttcataat cagatgattt tgagcctttc
    23341 gccagatgtg cttgatactg ttattttcta cggagaagat attgctgaat tagcccaact
    23401 tgctagtcaa atgttcccaa tcggacacgt ttattacttc aagaaaacag aagaccaaga
    23461 ccaatttgaa gacctagtta agcaggtcaa agaaagcctt ggggctcatg accaaatcct
    23521 gctcaaaggc tctaactcta tgaatctagc caagttggta gaaagtttag aaaatgaaga
    23581 caagtgattt tgtcaagtat ttgcaaagaa tgattgccat tacagatact ggattaacct
    23641 ttacaaaaga tccgtttgac cgtgagcgct acgaagactt gcgagacctt ctatctgaaa
    23701 tgttgaatca agcatcagac cttgattccg aagaagtggc agaagtcttg aagccaactt
    23761 ctgcttatgc gactccctta atggacgtcc gtgcttggat tgttgaggac gaaaagattt
    23821 gtctggttag gggacaagga gaggatagtt gggctttgcc aggtggcttt ggtgaagtcg
    23881 gctattctcc aactgaaaat attctcaagg aaattgaaga agaaaccggt tttaaagcca
    23941 aagttgaaag actgctagct gtttttgata ccaatcgttt ccaactacag agcaaacaat
    24001 atgcaaagtt tgtttttgaa tgtaagcttc tcgatggaca attccaagaa aatcaagaaa
    24061 tcgctgacct tcaatttttt gcaattgacc cactgccgaa tttatctgaa aaacgcatta
    24121 ccaaggagca aatcgagatt ctttggcagg tttatcaagg tcagagggag caatatcttg
    24181 actaagaaga tgattatcgt atttctaaat tcatttttct taagtagcat ggtataataa
    24241 aatgcaggaa aattttgaat catgaggaag actagatgaa tttatgggat attttcttta
    24301 cgactcaggc aaccgagccg cccaaatttg accttttttg gtatgttagc ctatttacgc
    24361 tcttagcctt aaccttttat acagcccatc gctatcgtga aaagaaggtt taccaacgat
    24421 ttttccaaat cttgcagact gttcagttaa tccttcttta tggttggtac tgggtcaatc
    24481 atatgccact gtcagaaagc ctaccctttt accattgccg tatggctatg tttgtggtac
    24541 tcttgcttcc tggtcagtcc aaatataaac aatactttgc attattggga acatttggga
    24601 cattagcagc ctttgtttat ccagtgccag atgcttaccc ttttccacat atcaccattc
    24661 tatcctttat ctttggtcat ttagcactct tggggaactc tctagtttat ctattgagac
    24721 agtataatgc gcgattgctg gatgtgaagg gaatttttct catgaccttt gccctaaatg
    24781 ccttgatttt tgtggtcaat ttggtgacag gtggcgatta cggatttttg acaaaaccgc
    24841 cattggttgg ggatcacggt ctagtagcta attatttact tgtttcaatt gtgctggtag
    24901 ctactatcag tttgactaag aaaatcttag aattcttttt agctcaagaa gcagaaaaaa
    24961 tgattgcaaa ggaagcttaa cacagagctt tcttttttgc tcttagagag tttttacaag
    25021 cagcttataa aataagaatt tctgaataga caaactcaaa aaatggctgg gaaatttagg
    25081 aaaaaagcaa gcacgattaa attttttgtg ttataatatt ttgtgaatag ctatgcctat
    25141 gtttagctat ggaataatac gaagtgcgaa acttggaaga tagagaggaa gcgatgtaat
    25201 ggctagagaa ggctttttta caggtctaga tattggaaca agctctgtca aggtgcttgt
    25261 ggccgagcag agaaatggtg aattaaatgt aattggcgtg agtaatgcca aaagtaaagg
    25321 tgtaaaggat ggaattattg ttgatattga tgcagcagca actgctatca agtcagccat
    25381 ttcccaagcg gaagaaaagg caggcatttc gattaaatca gtaaatgtcg gcttgcctgg
    25441 taatcttttg caggtagaac caactcaggg gatgattcca gtaacatctg atactaagga
    25501 aattacggat caagatgttg aaaatgttgt caaatcagct ttgacaaaga gtatgacacc
    25561 tgaccgtgaa gtcattacct ttattcctga agaatttatt gtggatggtt tccaagggat
    25621 tcgtgaccca cgtggcatga tgggggttcg ccttgaaatg cgtggtttgc tttatacagg
    25681 acctcgtact atcttgcaca atttgcgtaa gacggttgag cgtgcaggtg ttcaggttga
    25741 aaatattatc atttcaccac tagcaatggt tcagtctgtt ttgaatgaag gggaacgtga
    25801 atttggtgct acagtgattg atatgggggc aggtcaaacg actgtcgcta caatccgtaa
    25861 tcaagaactc cagttcacac atattctcca agaaggtgga gattatgtaa ctaaagatat
    25921 ctccaaggtt ttgaaaacct ctcgcaaatt agcggaaggc ttgaaactga attacgggga
    25981 agcctatccg cctcttgcaa gcaaagaaac cttccaagta gaggttattg gagaagtgga
    26041 agcagtcgaa gtgacggaag cctacttgtc agaaattatt tctgcacgaa tcaagcacat
    26101 ccttgaacaa atcaagcaag aattagatag aaggcgtcta ttggacctcc ctggtggtat
    26161 tgtcttaatc ggtgggaatg ccattttacc aggtatggtt gagcttgctc aggaagtctt
    26221 tggcgtccgt gtcaagcttt atgttccaaa tcaagttggt atccgtaatc cagcctttgc
    26281 gcatgtgatt agtttatcag aatttgcggg tcaattaaca gaagttaatc ttttggctca
    26341 gggagcgata aaaggtgaga atgacttaag tcatcagcca attagttttg gtgggatgct
    26401 gcaaaaaaca gctcagtttg tacaatcaac gcctgttcaa ccagctcctg ctccagaagt
    26461 agagtcggtg gcgcctacag aaccaatggc ggatttccaa caagcttcac aaaataaacc
    26521 gaaattagca gatcgtttcc gtggcttgat cggaagcatg tttgacgaat aaagaggaaa
    26581 aataaattat gacattttca tttgatacag ctgctgctca aggggcagtg attaaagtaa
    26641 ttggtgtcgg tggaggtggt ggcaatgcca tcaaccgtat ggtcgacgaa ggtgttacag
    26701 gcgtagaatt tatcgcagca aacacagatg tacaagcatt gagtagtaca aaagctgaga
    26761 ctgttattca gttgggacct aaattgactc gtggtttggg tgcaggaggt caacctgagg
    26821 ttggtcgtaa agccgctgaa gaaagcgaag aaacactgac ggaagctatt agtggtgccg
    26881 atatggtctt catcactgct ggtatgggag gaggctctgg aactggagct gctcctgtta
    26941 ttgctcgtat cgccaaagat ttaggtgcgc ttacagttgg tgttgtaaca cgtccctttg
    27001 gttttgaagg aagtaagcgt ggacaatttg ctgtagaagg aatcaatcaa cttcgtgagc
    27061 atgtagacac tctattgatt atctcaaaca acaatttgct tgaaattgtt gataagaaaa
    27121 caccgctttt ggaggctctt agcgaagcgg ataacgttct tcgtcaaggt gttcaaggga
    27181 ttaccgattt gattaccaat ccaggattga ttaaccttga ctttgccgat gtgaaaacgg
    27241 taatggcaaa caaagggaat gctcttatgg gtattggtat cggtagtgga gaagaacgtg
    27301 tggtagaagc ggcacgtaag gcaatctatt caccacttct tgaaacaact attgacggtg
    27361 ctgaggatgt tatcgtcaac gttactggtg gtcttgactt aaccttgatt gaggcagaag
    27421 aggcttcaca aattgtgaac caggcagcag gtcaaggagt gaacatctgg ctcggtactt
    27481 caattgatga aagtatgcgt gatgaaattc gtgtaacagt tgttgcaacg ggtgttcgtc
    27541 aagaccgcgt agaaaaggtt gtggctccac aagctagatc tgctactaac taccgtgaga
    27601 cagtgaaacc agctcattca catggctttg atcgtcattt tgatatggca gaaacagttg
    27661 aattgccaaa acaaaatcca cgtcgtttgg aaccaactca ggcatctgct tttggtgatt
    27721 gggatcttcg ccgtgaatcg attgttcgta caacagattc agtcgtttct ccagtcgagc
    27781 gctttgaagc cccaatttca caagatgaag atgaattgga tacacctcca tttttcaaaa
    27841 atcgttaagt aaatgaatgt aaaagaaaat acagaacttg tttttcgaga agttgcagag
    27901 gctagtctga gtgctcatcg agagagtggt tcggtctctg tcattgcagt taccaagtat
    27961 gtagatgtac cgacagcgga agccttgctt ccgctaggtg ttcatcatat cggtgaaaat
    28021 cgtgtagata agtttctgga aaaatatgaa gctttaaaag atcgagatgt gacttggcat
    28081 ttgattggta ccttgcaaag acgtaaggtg aaagatgtca ttcaatacgt tgattatttc
    28141 catgcattgg actcagtaaa gctagcaggg gaaattcaaa aaagaagtga ccgagtcatc
    28201 aagtgtttcc ttcaagtaaa tatttctaaa gaagaaagca aacacggttt ttcgagagag
    28261 gaactgctgg aaatcttgcc agagttagcc agactagata agattgaata tgttggttta
    28321 atgacgatgg caccttttga ggctagcagt gagcagttga aagagatttt caaggcgacc
    28381 caagatttac aaagagaaat tcaagagaaa caaattccaa atatgcctat gaccgagtta
    28441 agtatgggaa tgagtcgtga ttataaagaa gcgattcaat tcggttccac ttttgttcgt
    28501 ataggtacat cattttttaa gtaggagaga accatgtctt taaaagatag attcgataga
    28561 tttatagatt attttacgga ggatgaggat tcaagtctcc cttatgaaaa aagagatgag
    28621 cctgtgttta ctccagtaaa ttcttcacag gaaccggctc tcccaatgaa tcaaccttca
    28681 cagtcggctg gtacaaaaga gaacaatatc accagacttc atgcaagaca acaggaattg
    28741 gcaaatcaga gtcagcgtgc aacggataag gtcattatag atgttcgtta tcctagaaaa
    28801 tatgaggatg caacagaaat tgttgattta ttggcaggaa acgaaagtat cttgattgat
    28861 tttcagtata tgacagaggt gcaggctcgt cgttgtttgg actatttgga tggagcttgt
    28921 catgttttag ctggaaattt gaaaaaggta gcttctacca tgtatttgtt gacaccagtg
    28981 aatgttattg taaatgttga agatatccgt ttaccagatg aagatcaaca gggtgagttc
    29041 ggttttgata tgaagcgaaa tagagtacga taatgatttt tttaattcgt atgatttata
    29101 atgcagtgga tatttactcc ctgattttgg tagccttcgc tgtcatgtct tggtttccag
    29161 gtgcctacga atccagttta ggtcgttgga ttgtagcgtt ggtgaaacca gtgcttgctc
    29221 ccttgcaacg cctgccttta cagatagcgg gtcttgattt atctgtttgg gtcgcgattg
    29281 ttttggttcg atttttagga gaaaacctag tgcgttttct ggcgatgata ggatgaataa
    29341 agggatttat cagcatttct ccatagaaga tcgtccattt cttgacaagg gaatggaatg
    29401 gataaagaag gtagaagata gctatgctcc ttttttaact ccttttatca atcctcatca
    29461 ggagaagcta ttaaagattt tggccaaaac ctatggtctt gcttgtagca gtagtgggga
    29521 attcgtctcg agtgagtatg ttcgagtttt attataccca gattatttcc aaccagagtt
    29581 ttcagatttt gaaatatctc tccaggaaat tgtgtattcc aataaatttg aacatttaac
    29641 gcatgctaag attttaggga cagtcatcaa tcaattaggg attgaacgga aactttttgg
    29701 agatatccta gtagatgaag aacgggcgca gattatgatt aatcagcagt ttcttcttct
    29761 ctttcaagat ggactaaaga aaattggtcg tatacctgtt tcgctggagg aacgtccttt
    29821 caccgagaaa atagataagc tagaacagta tcgagaactg gatttatctg tgtctagttt
    29881 tcgattagat gttctttgtt caagttggag acttgattag tgtgagaaaa tttggtcgct
    29941 tgagattact tcaagataag ggacaaacga aaaaagagaa gaaaaaaata accgtccagt
    30001 tattattaag taagtgagga atagaatgcc aattacatca ttagaaataa aggacaagac
    30061 ttttggaact cgattcagag gttttgatcc agaagaagtc gatgaatttt tagatattgt
    30121 ggttcgtgat tacgaagatc ttgtgcgtgc gaatcatgat aaaaatttgc gtattaagag
    30181 tttagaagag cgtttgtctt actttgatga aataaaagat tcattgagcc agtctgtatt
    30241 gattgctcag gatacagctg agagagtgaa acaggcggcg catgaacgtt caaacaatat
    30301 cattcatcaa gcagagcaag atgcgcaacg cttgttggaa gaagctaaat ataaggcaaa
    30361 cgagattctt cgtcaagcaa ctgataatgc taagaaagtc gctgttgaaa cagaagaatt
    30421 gaagaacaag agccgtgtct tccaccaacg tctcaaatct acaattgaga gtcagttggc
    30481 tattgttgaa tcttcagatt gggaagatat tctccgtcca acagctactt atcttcaaac
    30541 cagtgatgaa gcctttaaag aagtggttag cgaagtactt ggagaaccga ttccagctcc
    30601 aattgaagaa gaaccaattg atatgacacg tcagttctct caagcagaaa tggaagaatt
    30661 acaagctcgt attgaggtag ccgataaaga attgtctgaa tttgaagctc agattaaaca
    30721 ggaagtggaa actccaactc ctgtagtgag tcctcaagtt gaagaagagc ctctgctcat
    30781 ccagttggcc caatgtatga agaaccagaa gtagctccag tgcatccgac aggtccaaca
    30841 ccagctacag aaactgttga ttcagcaccg ggatttgaag caccgcaaga atctgttaca
    30901 attttataag aaatattctg agaacaatat cttatcctta tattcccagc gagcaggaga
    30961 tggtgtgagt cctgcattcc ctatcgataa gattatcctc tcaaactatc aagtctgaat
    31021 ctagtaagat ttgacgttcc ccacgttacg ggataagagg gagaaagact aaaacttttt
    31081 ccgaataaag gtggtaccac gattttcgtc ctttttggaa gtcgtggttt ttaatttgtt
    31141 attatttata aaggagatac catgaaactc aaagacaccc ttaatcttgg gaaaactgaa
    31201 ttcccaatgc gtgcaggcct tcctaccaaa gagccagttt ggcaaaagga atgggaagat
    31261 gcaaaacttt atcaacgtcg tcaagaattg aaccaaggaa aacctcattt caccttgcat
    31321 gatggccctc catacgctaa cggaaatatc cacgttggac atgctatgaa caagatttca
    31381 aaagatatca ttgttcgttc taagtctatg tcaggatttt acgcaccatt tattcctggt
    31441 tgggatactc atggtctgcc aatcgagcaa gtcttgtcaa aacaaggtgt caaacgtaaa
    31501 gaaatggact tggttgagta cttgaaactt tgccgtgagt acgctctttc tcaagtagat
    31561 aaacaacgtg aagattttaa acgtttgggt gtttctggtg actgggaaaa tccatatgtg
    31621 accttgactc ctgactatga agcagctcaa attcgtgtat ttggtgagat ggctaataag
    31681 ggttatatct accgtggtgc taagccagtt tactggtcat ggtcatctga gtcagccctt
    31741 gctgaagcag agattgaata ccatgacttg gtttcaactt ccctttacta tgccaacaag
    31801 gtaaaagatg gcaaaggagt tctagataca gatacttata tcgttgtctg gacaacgact
    31861 ccatttacta tcacagcctc tcgtggtttg acggttggtg cagatattga ttacgttttg
    31921 gttcaacctg ctggtgaagc tcgtaagttt gtcgttgctg ctgaattatt gactagcttg
    31981 tctgagaaat ttggctgggc tgatgttcaa gttttggaaa cttaccgtgg ccaagaactc
    32041 aaccacatcg taacagaaca cccatgggat acagctgtag aagagttggt aattcttggt
    32101 gaccacgtta cgactgactc tggtacaggt attgtccata cagcccctgg ttttggtgag
    32161 gacgattaca atgttggtat tgctaataat cttgaagtcg cagtgactgt tgatgaacgt
    32221 ggtatcatga tgaagaatgc tggtcctgaa tttgaaggtc aattctatga aaaggtagtt
    32281 ccaactgtta ttgaaaaact tggtaacctc cttcttgccc aagaagaaat ctctcactca
    32341 tatccatttg actggcgtac taagaaacca atcatctggc gtgcagttcc acaatggttt
    32401 gcctcagttt ctaaattccg tcaagaaatc ttggacgaaa ttgaaaaagt gaaattccac
    32461 tcagaatggg gtaaagtccg tctttacaat atgatccgtg accgtggtga ctgggttatc
    32521 tctcgtcaac gtgcttgggg tgttccactt cctatcttct acgctgaaga tggtacagct
    32581 atcatggtag ctgaaactat tgaacacgta gctcaacttt ttgaagaaca tggttcaagc
    32641 atttggtggg aacgtgatgc caaagacctc ttgccagaag gatttactca tccaggttca
    32701 ccaaacggcg agttcaaaaa agaaactgat atcatggacg tttggtttga ctcaggttca
    32761 tcatggaatg gagtggtggt aaaccgtcct gaattgactt acccagccga cctttaccta
    32821 gaaggttctg accaataccg tggttggttt aactcatcac ttatcacatc tgttgccaac
    32881 catggcgtag caccttacaa acaaatcttg tcacaaggtt ttgcccttga tggtaaaggt
    32941 gagaagatgt ctaaatctct tggaaatacc attgctccaa gcgatgttga aaaacaattc
    33001 ggtgctgaaa tcttgcgtct ctgggtaaca agtgttgact caagcaatga cgtgcgtatc
    33061 tctatggata tcttgagcca agtttctgaa acttaccgta agattcgtaa cactcttcgt
    33121 ttcttgattg ccaatacatc tgactttaac ccagctcaag atacagtcgc ttacgatgag
    33181 cttcgttcag ttgataagta catgacgatt cgctttaacc agcttgtcaa gaccattcgt
    33241 gatgcttacg caaactttga attcttgaca atctacaagg ccttggtgaa ctttatcaac
    33301 gttgacttgt cagccttcta ccttgatttt gccaaagatg ttgtttacat tgaaggtgcc
    33361 aaatcactgg aacgccgtca aatgcagact gtcttctatg acattcttgt caaaatcacc
    33421 aaactcttga ctccaatcct tcctcacact gcggaagaaa tctggtcata tcttgagttt
    33481 gaagccgaag acttcgtcca attgtcagaa ttaccagaag ttcaaacttt tgctaaccaa
    33541 gaagaaatct tggatacatg ggcagccttc atggacttcc gtggacaagc acaaaaagcc
    33601 ttggaagaag ctcgtaatgc aaaagttatc ggtaaatcac ttgaagcaca cttgacagtt
    33661 tatccaaatg aagttgtgaa aactctactc gaagcagtaa acagcaatgt agctcaactt
    33721 ttgatcgtgt ctgagttgac catcgcagaa gaaccagctc cggaagctgc ccttagcttc
    33781 gaagatgtag tcttcacagt tgaacgcgct gcaggtgaag tatgtgaccg ttgccgtcgt
    33841 attgacccaa caacagcaga acgtagctac cacgcagtca tctgtgacca ctgtgcaagt
    33901 atcgtagaag aaaactttgc agatgcagtc gcagaaggat ttgaagagaa ataagattga
    33961 aaagtctagg taaaactcaa tttgagaaga aaagacaact aattttatag tctattaaac
    34021 gcattgtatc acgtttttga acacctgata tgatgcgttt tttatttatt ttaaaaattt
    34081 gcgaggtatg actttttata ctcaacaaga atcaaagaga aacttagcaa gctaacagta
    34141 gtaatataaa ataggaattt gatattaggg ataagattgg taaatagtgt aatattttta
    34201 caacaataaa tttatatagt tatttctggt ttctgaaaag tattatatta tattttattt
    34261 catattatac aaatttttat tttataatat cagaaaatac tttttttaaa aagcaaatat
    34321 gatacaattt tatttgaaaa aaaataaaaa aggagatttt attatgaaat caagtggtat
    34381 cgtcggtctt gtgggaggaa ttttacttct tatttgtcct tttgtcttgt tgggaacagc
    34441 ggtaaataca gctgctacaa ctcttaatgg aggagctact gcaggggctt tttcaggtgt
    34501 tgccttactc ttgaatgcct tgaagattgc aaatcttgtt cttggtatca ttgctattgt
    34561 ttactataaa ggagataagc atgtaggtgc agctccgtct gtactaatga ttgtttctgg
    34621 tgaagttagt ctcattccat tcttaggatg ggttgggggg attcttgcta ttatcggagg
    34681 atctctattc cttgcaacat tgaagaaatt caaatcagaa gaataaaagg tattttagca
    34741 tgaaaagaac aaaaaagttt atcggtatag gagtagctct attatctctt tctcttctag
    34801 ttgcatgtgg aacataaagt tcaaagaata cttcaacaag taatgatgag aagacagtag
    34861 caacatccaa tagttcaaaa gaaacaatca ctttcgatac accggttgta acagacgatg
    34921 cgattgaatc aatacgcact tatgcagatt atatagatct ttataaaaat atttttgatg
    34981 attattttac taaagctgag gaaggtttca aaggcacaac tatggaaaat aatgactcgt
    35041 ttactaaact aaaagagtca actcaaaaat tattcgatgc gcagaaaaaa aggttaaata
    35101 atgaagatag aatagaaaca accaaaaaca atgtgattgc caaacattgt caaacagtcc
    35161 tttccttttt ggttttgact agcttttttg tgaaaaattg tgtaaaatag aatagataaa
    35221 cgaggggaaa cctcggaaaa tttaaaggag aatccatcta atggtaaaat tggtttttgc
    35281 tcgccacggt gagtctgaat ggaacaaagc taaccttttc actggttggg ctgatgttga
    35341 tttgtctgaa aaaggtacac aacaagcgat tgacgctggt aaattgatca aagaagctgg
    35401 tatcgaattt gaccaagctt acacttcagt attgaaacgt gctatcaaaa caactaactt
    35461 ggctcttgaa gcttctgacc aattgtgggt tccagttgaa aaatcatggc gcttgaacga
    35521 acgtcactac ggtggtttga ctggtaaaaa caaagctgaa gctgctgaac aatttggtga
    35581 tgagcaagtt cacatctggc gtcgttcata cgatgtattg cctccaaata tggaccgtga
    35641 tgatgagcac tcagctcaca cagaccgtcg ttatgcttca cttgacgact cagtcattcc
    35701 agatgctgaa aacttgaaag tgactttgga acgtgctctt ccattctggg aagataaaat
    35761 cgctccagct cttaaagatg gtaaaaacgt attcgtagga gctcacggta actcaatccg
    35821 tgcccttgta aaacacatca aaggtttgtc agatgatgag atcatggacg tggaaatccc
    35881 taacttccca ccattggtat tcgaattcga cgaaaaattg aacgttgttt ctgaatacta
    35941 ccttggaaaa taaaaaattg taagcctagg attgatttct aggcttttta tgttagtatg
    36001 gaagtatgat aaggaataaa aaacaagatt atgtactggc ctacaagcaa ccagcttcaa
    36061 ccacttacat gggttgggaa gaagaagctt taccgatagg caatggttct ttaggagcaa
    36121 aagtatttgg ccttataggg gctgaacgga ttcaatttaa tgaaaaaagt ctctggtctg
    36181 gaggtccact tcctgatagt tcagattatc agggtggaaa tcttcaggat cagtatgttt
    36241 ttttagctga gattcggcag gctttggaga agagagatta caatctggct aaggaactgg
    36301 ctgagcagca cctaattggg ccaaaaacga gtcaatatgg gacctatctg tcttttgggg
    36361 atattcacat tgagttcagc cagcaaggta cgactttgtc tcaggtgacg gactatcaga
    36421 gacagctgaa tattagtaag gcacttgcga cgacttctta tgtctataag ggaacgcgat
    36481 ttgaacgtaa agcttttgcg agttttccag atgatctctt gattcaatgt tttactaagg
    36541 aagggttgga aactctagat tttactatag aactatcctt gacctgtgat ttggcttctg
    36601 atggaaagta tgagcaggaa aaatctgatt acaaggagtg taagttggat attactgatt
    36661 ctcatatctt gatgaaggga agagttaagg ataatgatct gcggtttgct agttatctag
    36721 cttgggaaac ggatggagat attagagttt ggtcagatag ggttcagata tcaggagcca
    36781 gttatgccaa tctcttcttg gccgctaaga cggattttgc ccaaaatcct gctagcaatt
    36841 atcgcaagaa actagattta gagcaacagg tgatagactt ggtggacaca gctaaagaaa
    36901 agggctatac ccaattgaaa tcaaggcata tcgaggacta ccaagcctta ttccagcgtg
    36961 ttcaattgga tttggaagct gatgttgacg catccactac agatgatttg ttaaaaaatt
    37021 ataagccaca agaagggcag gctttggagg agctgttctt ccagtatgga cggtatttat
    37081 tgattagttc gtccagagac tgcccagatg ctctaccagc taacctacag ggagtctgga
    37141 atgcggtcga caatcctcct tggaattcgg actatcactt aaatgtcaat ctgcagatga
    37201 attattggcc agcctatgtt accaatctcc tagagacggt ctttccagtc atcaactatg
    37261 tagatgattt gcgtgtctat ggtcgtctag cggctgtaaa gtatgcagga atcgtctctc
    37321 aaaaaggtga ggaaaatggt tggttggttc atactcaagc gactcccttt ggttggacgg
    37381 cacctggttg ggattactat tggggttggt caccagctgc caatgcgtgg atgatgcaaa
    37441 ccgtttatga agcctattca ttttataggg accaagacta tctcagggag aaaatttatc
    37501 ccatgttgag ggaaacggtt cgtttttgga atgccttttt acataaggat cagcaggcgc
    37561 agcgttgggt ctcttctccg tcttattccc cagaacatgg gccgatttcg attggcaata
    37621 cctatgacca atctctgatt tggcagttat ttcatgattt tattcaggct gctcaggaat
    37681 tgggactgga tgaggacttg ttgactgagg ttaaggagaa gtctgattta ctaaatcctt
    37741 tgcaaatcac tcaatctggt cgaatcaggg agtggtatga ggaggaagag cagtattttc
    37801 aaaatgagaa agtggaggcc cagcatcggc acgcttccca tctagtggga ctctattctg
    37861 gcaatctctt tagctacaag ggacaagagt atattgaagc ggcgcgtgct atcctcaatg
    37921 atcgtggaga tggcggcaca ggctggtcca aggctaataa gatcaatctc tgggcgcgtt
    37981 tgggagatgg caatcgagcc cataaattat tggcagagca gttaaagaca tccaccttgc
    38041 caaatctttg gtgtagccat cctccttttc agatagatgg taattttggt gctactagtg
    38101 gcatggcaga aatgttactc cagtctcatg cagcttatct ggtacctcta gctgccctac
    38161 ctgatgcttg gtcaacaggt tctgtttcag gcttaatggc acgtggacat tttgaagtga
    38221 gcatgagctg ggaagataaa aaactcttac agttgaccat tttatcaagg agtggaggag
    38281 atttgcgagt ttcttatcca gatattgaga agagtgtgat taaaatgaat caagaaaaaa
    38341 taaaagcgaa atgcatgggg aaagattgta tttcggtggc aacagcagaa ggtgatcttg
    38401 ttcaatttta tttttaagaa gatgttataa ggcagtaatt tgaaacttcc ttttaataag
    38461 gatttgagaa tataggcagt ttccaactag ttgaaaaagc gttataatga taataggaag
    38521 taatactcaa tgaaaatcaa agagcacaaa ctaggaagct agccgcaggt tgctcaaaac
    38581 agtgttttga ggttgtagat ggaagctgac gtggtttgaa gagagatttt cgaggagtat
    38641 aatttgtttg atagagggtg ggtctgatgg cttatattga gatgaaacac tgttacaagc
    38701 gttatcaggt tggggacacg gagattgtgg ccaatcgtga tgtgaatttt gagattgaaa
    38761 agggggagct ggttattatc cttggtgctt caggtgcagg caagtcaaca gttcttaacc
    38821 ttcttggggg aatggatacc aatgatgaag gggaaatctg gattgatggt gttaatattg
    38881 cggattatag ttcccaccag cgtaccaatt accgtagaaa tgatgtgggg tttgtttttc
    38941 agttttataa tctagtttct aatctgacag ctaaggaaaa tgtggaactg gcttctgaaa
    39001 ttgtgacaga tgccttgaat cctgatcagg tcttgacaga tgtaggtctg gctcatcgtc
    39061 tcaataactt tccagcccag ctttctggag gggagcaaca gcgagtctcc attgcacgcg
    39121 cggtagccaa aaatcctaaa attctccttt gtgatgaacc gactggagcc ttggattatc
    39181 agacgggcaa gcaggttttg aaaattctcc aagacatgtc tcgtcaaaag ggagcgacgg
    39241 tgatcatcgt gactcataat ggagctttgg cgcccattgc tgatcgcgtg attcaaatgc
    39301 acgatgccag tgtcaaggat gtggtgctca accagcatcc tcaggatatt gacagtttgg
    39361 agtactagca tgatcaagcg aaaaacttat tggaaggact taattcagtc cttcacaggc
    39421 tccaaggggc gttttttatc catcttgatc ctgatgatgt tgggatctct agccttagta
    39481 ggcctcaaag taaccagtcc caacatggag gcgacagcta atgcttattt aacaactgct
    39541 caaaccttgg atttggcagt catgtctaac tatggcttgg atcaagcaga ccaagaagaa
    39601 ctaaaacaga cggagggcgc agaggtcgag tttggctatt tgacagatgt gactatggat
    39661 aatgggcagg atgccattcg gctgtactcc aaaccagagc gaatttcaac ctttcagcta
    39721 agaaagggac gacttcctca gtcagacaag gaaatcgctt tggccactca tttgcaaggc
    39781 caatacagcg tgggacagga gattagtttt aaagaaaaag aagagggtca ttcctcttta
    39841 aaagaccata cttataccat tactggtttt gtggattcgg ctgaaatcct ctcccagcga
    39901 gatatgggct acgcaggaag tggaagtggg actctgacag cctatggggt gattttacct
    39961 agtcagtttg atcagaaagt ctacaatata gctcgtttga aatatcaaga tttagcaggt
    40021 ttaaatgcct tttcatcagc ttatgaagaa aaatccaagc aacatcagga agaccttgaa
    40081 caaactttat cagataatgg caaggtacgt ctgcaacttt tgaaaaaaga aggacaagag
    40141 tctctagaca aggggcaaga gacccttgac aaggctcaga ctaatttgca ggaaggcaag
    40201 cgtcgtttag cagctgctca agctcgtata caggctcaag aaagtcaact agccttgttt
    40261 cctcaagttc agagagagca ggctagtgct caacttaccc aagccaagca ggaattgggc
    40321 aaggaagagg ataaactaaa gcaagctgaa caaaatctag cccaagaaaa ggaaaaatta
    40381 gaaaaacatc agcaagtctt ggacgatttg gcggagccaa ggtatcaggt ctataatcgt
    40441 cagaccatgc caggtggtca gggctatctt atgtatagca atgcttcatc cagtattcga
    40501 gcagtgggca atatctttcc tgtggtactt tatgccgtag catccatggt gacctttacg
    40561 accatgactc gctttgtaga cgaagagcga actcatgcag ggatttttaa ggccttgggt
    40621 taccgtagta aggatattat caccaagttt ctcctttatg gactagtagc tgggactgtc
    40681 ggaacggctc taggtagtat acttggtcat tatttgctag ccagtgtaat ttcaagtgtc
    40741 attacaaaag gcatggtggt gggagaaacc cagattcagt tctattggac ctatagctta
    40801 ctagctcttg tcttgagctg gttggcgagt gtgttaccag cctatctggt ggcttggagg
    40861 gaacttcatg ccgaagcagc ccagcttcta cttcctaaac ctcctgtcaa aggagctaaa
    40921 atcttattgg agcgtatcgg ttttatctgg cgtcgtctca gttttactca taaggtaaca
    40981 gcccgcaaca tctttcgtta taagcagaga atgttgatga caatctttgg tgtggcaggt
    41041 tctgtagctc tgctctttgc aggtttggga atccaatctt ctgtagcagg agttccgtct
    41101 aaacagtttc aacaaatcca acagtatcag atgcttgtct ctgaaaatcc tagtgcgacc
    41161 aatcaggaca aggtagagct agcagaagtg ttgaaagggc aggagatact agcctaccag
    41221 aaaatctatt ctaaaacgct agacaaggat ttcaaaggca aggctggtct tcaaaacatt
    41281 actcttatga tgatagagaa ggaagatttg actcccttta tccatcttca acatcatcag
    41341 caggagctga cattaaaaga tggcatcgtt attacagcta aactcgccca gctggcaggt
    41401 gtcaaggttg ggcagacttt agaaattgaa ggtaaggaac taaaggtcgc tgctattact
    41461 gagaactacg ttggtcactt tatttatatg agtcaggcta gctatgagca actttacgga
    41521 cagctacccc aagccaacac ttatctggtc tcattaaggg ataccagtgc aactagtatc
    41581 gaaagtcagg cgggcttgct tatgaatcaa tctgcggtgt ccagcgttgt ccaaaatgct
    41641 tcagccattc gactctatcg ctagctcact caatcagacc atgaccatct tggtcatcgt
    41701 atcagttcta ttagctattg tcatccttta caatctgacc aatatcaacg tagctgagag
    41761 aatccgtgaa ctctccacta tcaaggttct cggttttcat aataatgaag tcaccctcta
    41821 catttaccgt gagacgattg tgctgtccct tgtgggaatc gtacttggtc tggtagctgg
    41881 tttctattta caccaatttt tgattcaaat gatttcgcct gcgactattc tcttttatcc
    41941 gcaggtaggc tgggaagtct atgtaatccc agtggcaaca gtaagcatca ttttgacctt
    42001 gcttggtttc ttcgtcaatt attatctgag aaaggttgat atgttagaag ccctgaaatc
    42061 tgtagagtaa ggtagttatt tttagctgat tgaacttcta tttactaata ttcaaaaatc
    42121 ctctgtcaca aagagcaggg agctctttgt gacagaggat tttttctata gggctttagc
    42181 agctgcaatt gcggcttcga agtttggctc agaattgata ttatccacgt attcaacgta
    42241 gcgaatcgta ttgtcagtat cgaggacaaa gactgcgcgt gctaataggt gccattcgtt
    42301 gatcaagagg gcataatcgc gcccgaaaga atggtcaaag tagtctgaaa gcataatggc
    42361 attgtcaagg ccttcagcac cgcaccaacg tttttgagca aaaggtaggt ccattgaaac
    42421 agtcaatacg accgtgttgt ccagtccagc caattcttca ttaaaacgac gtgtttgagt
    42481 tgagcagatg cctgtatcga tagaaggaac gacactcaag acttttttct tgccatcaaa
    42541 atcagccaga gattttttag aaagatctgt tgtagtaaga gaaaaatcaa gcgccttgtc
    42601 gccgacttgt agttgtttac ctgtaaagct cacaggattt ccgagaaaag ttaccatagg
    42661 atactccaat cttttttctt ccattgtatc tgaaacagtc agaattttcc aatgatttga
    42721 ccggaaatgt gggcatagaa aaaacgccag ctcacatgag aatgacgttt ttcagaggct
    42781 tattttgcca atccttcagc aatcttgtca aggttgtatt tcatcatgct gtagtagctg
    42841 tcgccttctt taccttgttc tgcgatagag tcagtaaaga tttgtgcgta gattgggatg
    42901 tttgtgtctt gagaaacagt tttcattgga cggtcatcca cacttgattc tacaaagagt
    42961 gatggaactt ttgtttggcg aagtttttca accaaggtct tgatttgttc aggagttcct
    43021 tcttcttcag tattgatttc ccagatgtaa gcacttggga caccataggc tttagagaag
    43081 tatttgaatg ctccttcgct ggttacaatg agtttctttt cagcagggat cttattaaat
    43141 ttatccttac tttctttatc aagtttgtct aacttatcag tatattcttt gagatttttt
    43201 tcatagaatt ctttattgtt agggtctttg gcgctcaatt gtttggcgat atttttagca
    43261 aaaataatac cgttttcaag gttaagccaa gcgtgtgggt cttcttttcc tttttcattt
    43321 tgaccttcaa ggtagataac atcaacgccg tcgctgactg cgaagtagtc tttgttttca
    43381 gttttcttgg cattttctac caattttgta aaccaagcat tgccacctgt ttcaaggttg
    43441 ataccgttat agaaaatcaa atcagcctca gaagttttct taacgtcttc aggaagtggt
    43501 tcgtattcgt gtgggtcttg cccaatcgga acgatactat gaaggtcaat tttgtcacca
    43561 gcaatatttt tagtaatatc agcgatgatt gagtttgtag caacaacttt tagtttttga
    43621 ccagaagttg tatctttttt tccgctagca catgctacaa gaatgattgc agaaagaaag
    43681 agaacgagta atgtacctaa ttttttcatt agatcctcca aattattagg gctttgcccc
    43741 ttattttaac aaatgtttat ttttcagttt caaatatcgt tgtttgggag cgataaagaa
    43801 gctaatgaga aagaaactag cagctgtaag cacgatacta gaacctgccg caacattaaa
    43861 actatagcca ataaagagtc ccaaaactga agcagtagct ccgaaggttg aggaaaggaa
    43921 aatcatgctt ttcagactat tagcatacag ataagcagtt gcagctgggg taatcagcat
    43981 ggctacaatc aggatagttc cgacactttg catggctgtc acagacacga gagtcaggag
    44041 taccatgaga aggtagtgat agaaattgac aggcattccc atggctttag ccaagagttc
    44101 atcaaaggaa gttatcaaga gttgcttgaa gaaaatccag attaacaaga ggatggctgc
    44161 ccccacaccc atagtaataa acatatccgt atcttggacg gccaggatat taccaaaaag
    44221 gatatggaaa aggtcagttg aacttttagc gacaccaatc aagatgatac cgagggctaa
    44281 gaaagaagaa aaggtaatgc cgatggcggt atcgcttttg ataatcgagt ttcctttgat
    44341 gtaggtaatg atgatggcag ctagcaatcc aaagacaatg gctccgataa agaagtcaag
    44401 gcccaagatg aaggagaggg ctacacctgg taagacagca tgtgaaatgg catctcccat
    44461 gagtgacatc ccgcgtagaa taatgaaaca tcccacagct ccagctacaa tcccgacgac
    44521 aatagctgtt atcaaggcat tttgtaggaa atggaatttt tgcaatccat cgataaattc
    44581 tgcaatcata ggtcacctcc attgaaaaag agttgattac cgtaagcttc ttttagattg
    44641 gtttcggtaa aagtttcttt tgttggacca aaggcaatca cttctcgatt gacaagtaag
    44701 acttgatcga agtagtgggg aatcttgctg aggtcgtggt gaacgatgag aaccgtcttc
    44761 ccagcttttt tcaaatctct cagcgtattc atgatgattt cctcactgac agagtcaatc
    44821 ccagcaaagg gttcatccaa gaggatatag tcggcttcct gcaccaaaca tctggcaatc
    44881 aaaacccgct ggaattgacc tccagacagt tgactaattt gacgttcagc gtagtcagct
    44941 aggccgacga tttcaagggc ctcttgcact ttcttccaat gtttagcctt taaacttcga
    45001 aagagaggaa tagagggaaa tagtcctaac gagacgcatt ccttgacctt gatgggaaag
    45061 ttgtagtcga tattgatttt ttgttcgaca taggcaattc ggtgtaagga ttttttaact
    45121 tccttgtcat cgagaaatgc ctgaccttga tgtgggataa ttcccagcat accttttaat
    45181 agtgttgatt tcccagcgcc gtttggacca atgatgccgg taattgttgg tccatggagc
    45241 actagtgaaa tatccttaag tgccaacgtt tctttgtagg agacactgag gttttcgata
    45301 cgtatcataa acttgtattc ctcctgtctc ttaatataca ttaaaaaaaa aattaagtca
    45361 agttaatttt tgaaaaaatt aaaataataa ctgaaaaata ga
//
LOCUS       DAVBCA010000010        43681 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.010, whole genome shotgun sequence.
ACCESSION   DAVBCA010000010 DAVBCA010000000
VERSION     DAVBCA010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 43681)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43681)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43681
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.010"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            1..235
                     /locus_tag="VQU19_000498"
                     /pseudo
     CDS             1..235
                     /locus_tag="VQU19_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
     gene            232..450
                     /locus_tag="VQU19_000499"
     CDS             232..450
                     /locus_tag="VQU19_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2479801.1"
                     /translation="MSISPRFEALEQAIASKDLEKVREAFKKMNSTWTINESVVRDNS
                     TAHYGRVETAISFLPSSMETEPTDESGT"
     gene            complement(507..791)
                     /locus_tag="VQU19_000500"
     CDS             complement(507..791)
                     /locus_tag="VQU19_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HET2479802.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(845..1780)
                     /locus_tag="VQU19_000501"
     CDS             complement(845..1780)
                     /locus_tag="VQU19_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HET2479803.1"
                     /translation="MEICQQILEKIKEYNTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQKILKQYNVTDAETAAIVGAPGRIDSVSLWGIFVEQADGHYRVRLRSKIHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            1884..2327
                     /locus_tag="VQU19_000502"
     CDS             1884..2327
                     /locus_tag="VQU19_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HET2479804.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELAAKVG"
     gene            2443..2709
                     /locus_tag="VQU19_000503"
     CDS             2443..2709
                     /locus_tag="VQU19_000503"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HET2479805.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREEVIFEKVRSRVEDKRYQETIVATFSYILKRSRDYQDQNIK"
     gene            2706..3080
                     /gene="crcB"
                     /locus_tag="VQU19_000504"
     CDS             2706..3080
                     /gene="crcB"
                     /locus_tag="VQU19_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HET2479806.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIFLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYFSLV
                     LYLLLSIGGGLLLAYYLGRKKW"
     gene            3074..3403
                     /gene="crcB"
                     /locus_tag="VQU19_000505"
     CDS             3074..3403
                     /gene="crcB"
                     /locus_tag="VQU19_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HET2479807.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            3522..3869
                     /gene="rplS"
                     /locus_tag="VQU19_000506"
     CDS             3522..3869
                     /gene="rplS"
                     /locus_tag="VQU19_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HET2479808.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            3912..3983
                     /locus_tag="VQU19_000507"
     tRNA            3912..3983
                     /locus_tag="VQU19_000507"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3945..3947,aa:Arg,seq:cct)
     gene            complement(4150..5148)
                     /locus_tag="VQU19_000508"
     CDS             complement(4150..5148)
                     /locus_tag="VQU19_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001008999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAP domain-containing protein"
                     /protein_id="HET2479809.1"
                     /translation="MNFFSKLFNLKQNNHNRDTNSDCNNFYLNELECGLTPGQLILID
                     WTQKTGRNYNFPRYFKYSLQIDPESTHNQLYKLGYFTKNKTLSYLTVVELKTILSKHN
                     LATSGKKAELITRIINNVNIDNLDIPFEFKLTKEAQNLIIEHSDYIKAYYDKDISMED
                     YCKEKNNISFKATFGDIKWSLLNKQAHRNTVSGDFGCLSNTRKAQGRHLEQEGNIKHA
                     LIYYIESLIITISGLENNFSATDYPVYYPDSIPDYSLKHIQTLMESLSDDDYDFAFDE
                     ALFRFSILNANHFLSKEDIDYLRVNLPRSTAEEINNYLKKYECYSPLNNLELDDFE"
     gene            complement(5191..5997)
                     /gene="yidA"
                     /locus_tag="VQU19_000509"
     CDS             complement(5191..5997)
                     /gene="yidA"
                     /locus_tag="VQU19_000509"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HET2479810.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGKYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYERYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRPMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTWVL"
     gene            complement(6010..7314)
                     /locus_tag="VQU19_000510"
     CDS             complement(6010..7314)
                     /locus_tag="VQU19_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HET2479811.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTVTAALLHDLGHGAYS
                     HTFENLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPVENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKNFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSQRFVNRKVFKSITFSQEDQDQLTSMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESQNPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            7386..7763
                     /locus_tag="VQU19_000511"
     CDS             7386..7763
                     /locus_tag="VQU19_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HET2479812.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELMMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTSHYQVDRQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            7854..8186
                     /locus_tag="VQU19_000512"
     CDS             7854..8186
                     /locus_tag="VQU19_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HET2479813.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDDFLQEQIEI
                     LTSIDNRE"
     gene            8198..9769
                     /gene="ffh"
                     /locus_tag="VQU19_000513"
     CDS             8198..9769
                     /gene="ffh"
                     /locus_tag="VQU19_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HET2479814.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(9964..11247)
                     /locus_tag="VQU19_000514"
     CDS             complement(9964..11247)
                     /locus_tag="VQU19_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HET2479815.1"
                     /translation="MKQESTVDLLLDVDQRPSAGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLKANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLLGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(11550..12263)
                     /gene="rsmG"
                     /locus_tag="VQU19_000515"
     CDS             complement(11550..12263)
                     /gene="rsmG"
                     /locus_tag="VQU19_000515"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HET2479816.1"
                     /translation="MKPKTFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            12357..12917
                     /locus_tag="VQU19_000516"
     CDS             12357..12917
                     /locus_tag="VQU19_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HET2479817.1"
                     /translation="MTWIILGVIALIVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTSEEEKSVPKVDFSGLGD"
     gene            12919..13818
                     /gene="htpX"
                     /locus_tag="VQU19_000517"
     CDS             12919..13818
                     /gene="htpX"
                     /locus_tag="VQU19_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HET2479818.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSSMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKQM"
     gene            complement(13862..15421)
                     /locus_tag="VQU19_000518"
     CDS             complement(13862..15421)
                     /locus_tag="VQU19_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET2479819.1"
                     /translation="MHYRHSRKGNSMIKINHLTITQNKDLRDLVSDLSMTIQDGEKVA
                     IIGEEGNGKSTLLKTLMGEDLSDFTIKGDIQSDYQSLAYIPQKVPEDLKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKTAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLAQELQLTVRGQEKIGIIGPNGVGKSTLLAKLQQLLNDKREISLGFMPQDYHK
                     KLQLDLSSIAYISKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSIIYRMTE
                     HGLKLVNLEDL"
     gene            complement(15660..15977)
                     /locus_tag="VQU19_000519"
     CDS             complement(15660..15977)
                     /locus_tag="VQU19_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HET2479820.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQGTADDIRLQELLNTTMQELKKT
                     EKLNNSILIDLEKFYQPTSPLIGLGSLKLNDQARTAWRNYDKIHYEHVKHVLSLYGPV
                     FGF"
     gene            16156..16698
                     /locus_tag="VQU19_000520"
     CDS             16156..16698
                     /locus_tag="VQU19_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HET2479821.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNQLDQEVLDDD
                     LVLPIENGELDLAESVSDNILLNIPIKVLTAEEEAGQGFISGNDWQIMTEEEYQAQQA
                     VKKEENSPFAGLQGLFDGDE"
     gene            16698..17327
                     /gene="nth"
                     /locus_tag="VQU19_000521"
     CDS             16698..17327
                     /gene="nth"
                     /locus_tag="VQU19_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HET2479822.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            17538..18059
                     /gene="pyrR"
                     /locus_tag="VQU19_000522"
     CDS             17538..18059
                     /gene="pyrR"
                     /locus_tag="VQU19_000522"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HET2479823.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            18078..19001
                     /locus_tag="VQU19_000523"
     CDS             18078..19001
                     /locus_tag="VQU19_000523"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HET2479824.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGAELFFAGPEEWRSQEFADYGKFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            19051..20130
                     /gene="carA"
                     /locus_tag="VQU19_000524"
     CDS             19051..20130
                     /gene="carA"
                     /locus_tag="VQU19_000524"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HET2479825.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            20442..23618
                     /gene="carB"
                     /locus_tag="VQU19_000525"
     CDS             20442..23618
                     /gene="carB"
                     /locus_tag="VQU19_000525"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HET2479826.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKERPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDQVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKNVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
     gene            complement(23893..24702)
                     /locus_tag="VQU19_000526"
     CDS             complement(23893..24702)
                     /locus_tag="VQU19_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET2479827.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDQFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNIPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
     gene            complement(24704..25507)
                     /locus_tag="VQU19_000527"
     CDS             complement(24704..25507)
                     /locus_tag="VQU19_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET2479828.1"
                     /translation="MKQLTVEDAKQIELEILNYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPMDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRLVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSATFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            complement(25517..27004)
                     /gene="tacF"
                     /locus_tag="VQU19_000528"
     CDS             complement(25517..27004)
                     /gene="tacF"
                     /locus_tag="VQU19_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HET2479829.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFTDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGDILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVAPEYYLLTTML
                     SEASLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            27340..28047
                     /locus_tag="VQU19_000529"
     CDS             27340..28047
                     /locus_tag="VQU19_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HET2479830.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKKIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDSIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            28052..29074
                     /locus_tag="VQU19_000530"
     CDS             28052..29074
                     /locus_tag="VQU19_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HET2479831.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPEAEIVVIGRHWEKLELFSFAKECYITDNI
                     PEELAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFKNAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            29091..29960
                     /gene="licA"
                     /locus_tag="VQU19_000531"
     CDS             29091..29960
                     /gene="licA"
                     /locus_tag="VQU19_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HET2479832.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     VKGLASYGGSDEK"
     gene            29950..30828
                     /locus_tag="VQU19_000532"
     CDS             29950..30828
                     /locus_tag="VQU19_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HET2479833.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            30840..31529
                     /locus_tag="VQU19_000533"
     CDS             30840..31529
                     /locus_tag="VQU19_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HET2479834.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQNIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     HKLEEILKNEN"
     gene            31627..32475
                     /gene="dprA"
                     /locus_tag="VQU19_000534"
     CDS             31627..32475
                     /gene="dprA"
                     /locus_tag="VQU19_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HET2479835.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            33359..34402
                     /locus_tag="VQU19_000535"
     CDS             33359..34402
                     /locus_tag="VQU19_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HET2479836.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGHNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFYTESEEQ"
     gene            34569..36656
                     /gene="topA"
                     /locus_tag="VQU19_000536"
     CDS             34569..36656
                     /gene="topA"
                     /locus_tag="VQU19_000536"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HET2479837.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQNGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            36877..37236
                     /locus_tag="VQU19_000537"
     CDS             36877..37236
                     /locus_tag="VQU19_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HET2479838.1"
                     /translation="MRIIYLIIGFLSLTLAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQAYVADFRETKSIARERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            37329..37961
                     /locus_tag="VQU19_000538"
     CDS             37329..37961
                     /locus_tag="VQU19_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HET2479839.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGALTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLENRQTFIDQVGVTQLHGTKVVF"
     gene            38005..38661
                     /locus_tag="VQU19_000539"
     CDS             38005..38661
                     /locus_tag="VQU19_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HET2479840.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVYMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            38680..39774
                     /locus_tag="VQU19_000540"
     CDS             38680..39774
                     /locus_tag="VQU19_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HET2479841.1"
                     /translation="MNFQLAKYSLLKRFLENIGFTTLEEYGAIFKYLIENVKTDRQII
                     YSPHCHDDLGMAVANSLAAVKNGAGRVEGTINGIRERAENAALEEIAVALNIRQDYYQ
                     VETSIVLNETINTSEMVSRFSGIPVPKNKAVVGGNTFSHESGIHQDGVLKNPLTYEII
                     TPELVGVKILLGKLSGRHAFVEKLRELALDFTEEDIKPLFAKFKALVDKKQEITDADI
                     RALVAGTMVENPEGFHFDDLQLQTHADNDIEALVSLANMDGEKVEFNATGQGSVEAIF
                     NAIDKFFNQSVRLVSYTIDAVTDGIDTQDRVLVTVENRDTETIFNAAGLDFDVLKASA
                     IVYINANTFVQKENAGEMGRSVSYHDMPSV"
     gene            39786..40823
                     /gene="leuB"
                     /locus_tag="VQU19_000541"
                     /pseudo
     CDS             39786..40823
                     /gene="leuB"
                     /locus_tag="VQU19_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
     gene            40820..41089
                     /locus_tag="VQU19_000542"
     CDS             40820..41089
                     /locus_tag="VQU19_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HET2479842.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKSKARRRVWRIPEKILLIL
                     AFTFGGFGAWLAGIIFHHKTRKWYFKIVWFLGMVTTLVALYFIWR"
     gene            41093..41452
                     /gene="leuD"
                     /locus_tag="VQU19_000543"
     CDS             41093..41452
                     /gene="leuD"
                     /locus_tag="VQU19_000543"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HET2479843.1"
                     /translation="MAGSSREYAAWALADYGFKVVIAGSFGDIHYNNELNNGMLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            41614..42182
                     /locus_tag="VQU19_000544"
                     /pseudo
     CDS             41614..42182
                     /locus_tag="VQU19_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019771122.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
     gene            42276..42341
                     /locus_tag="VQU19_000545"
                     /pseudo
     CDS             42276..42341
                     /locus_tag="VQU19_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849983.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
     gene            42504..>43681
                     /locus_tag="VQU19_000546"
     CDS             42504..>43681
                     /locus_tag="VQU19_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HET2479844.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTK
                     LLCIYTEGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELMSKTYPELEPSKL
                     GTMLFEYSKLFMENKEDNSTMDSSNNFRHQLTQSLLKSPNLILRGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     TQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLP
                     "
BASE COUNT        13255 a         7811 c         9435 g        13180 t
ORIGIN      
        1 ccttaaagat tccgactaat attggctttg catttattcc tccatacaca ccagagatga
       61 acccattgaa caagtgtgga aagagattcg taaacgtgga tttaagaata aagcctttta
      121 aactttggaa gatgtcatga atcaactcca agatgttata caaggactgg agaaggaggt
      181 gataaagtcc atcgttaatc ggagatggac tagaatgctt tttgaaagca gatgagtata
      241 agtcctcgtt ttgaagcctt ggaacaggcc attgcctcca aagatttgga aaaagtccga
      301 gaagctttta agaaaatgaa ttccacttgg accatcaatg aaagtgtggt tcgtgacaat
      361 agtacagctc attatggacg tgttgaaaca gctatttcct tcctgcctag tagcatggaa
      421 accgaaccta cagatgagtc tggaacatga aaacagcagt tgatttcaag aaacaaaaaa
      481 gaacagtcga aactgttctt ttatcattat ttgagaccgt attttttgtt gaaacgatcc
      541 acgcgtccat ctgcttgagt gaacttttga cgtccagtgt agaatgggtg tgagtctgat
      601 gaaatttcca cacggatcaa tgggtaagtt tcgccttcga actcaactgt ttcgttagag
      661 cgttttgttg aaccgctaag gaattggtaa ccagtagttg tgtccatgaa gacaactggg
      721 cgatattctg gatggatatc ttttttcatt ttgcaatatt tcctttctgc catggtctct
      781 ttgcgagcca tagattgtta ccatactagt ctatcagatt ctgaaaagtt tggcaagtat
      841 tttatcagtt tttaagcaag ttttttaact tttggtagat gatttcattt tcttctaggc
      901 tataggaatt agcaccactt gctagagggt ggcctccacc atcatgctcc ttggcgattt
      961 cattgatagg atggatttta ctgcgtaagc gaacgcggta gtggccatca gcctgttcca
     1021 caaaaattcc ccagagacta acactatcaa tacgcccagg tgcacctaca atggccgcag
     1081 tttcagcatc ggttacattg tattgtttca agattttctg actcaggata acgcgagcag
     1141 caccattttc atccacttcc agatggtcgt agatgtagcc ttgcagttta gcaattttgt
     1201 agctcatagt gtccattttg cgagtgagag ccgcaaagtc aaagttatgt tctctcaaat
     1261 aagcagccag gcgaagagtc cgtgcagtgg tagaagggta gaggaagcga cctgtatcac
     1321 cgacaattcc tgcaaagagc aactcagcat cgcgatctgc caaggctagt tgggttgttt
     1381 gggcaaatag ggtaatcatc tcgctagcgc tacttgaact agtatcgacc caagacaggt
     1441 caccgtatac atcatcattt ggatggtggt caatcttaat gagaaaatca ccttgactat
     1501 agcgcttatc atcgatacga gcagtattag ctgtatcaca gacgatgaca agtgcgcctt
     1561 ggtaggctct atcttcaaca agatccatct cagccatcca agtaagagtt ggttcatcaa
     1621 aaccgacggc tttgatggtt ttttctggga aatgatgttc cagcaaggct ttcaatccca
     1681 cctgacttcc caaggcatca gggtctggtt tcatatgacg atgaatgata atggtgttgt
     1741 attctttaat tttttctaaa atttgttggc aaatctccat aaataacctc aattctttct
     1801 catttcattg tagcacaaga atttttattt ttaaaatgaa aaagatgtga tataatggag
     1861 aaagataaat tgaggaggac gatatggcat tagcaaaaat tgtatttgcc agtatgaccg
     1921 gtaataccga agaaattgca gatattgtag cagacaaatt acgtgacttg ggcttggatg
     1981 ttgatgttga tgaatgtaca actgttgacg cttcagactt cttggaagca gacatcgcta
     2041 tcgttgcgac ctatacttat ggtgatggtg aattgccaga tgagatgatg gacttctacg
     2101 aagacctagc agatctcaac ttgaatggca aaatctacgg agtggtcggc tcaggagata
     2161 ccttctacga tgaattctgt aaggctgttg atgactttga ccgtgtcttt gtgtcaacag
     2221 gagcagaaaa aggttcagag tgtgttaaag ttgatctttc tgccgaggaa gaagatattg
     2281 aacgcttgga acaattcgca gaagaattgg ctgctaaagt aggataagca taaaagtgcg
     2341 ctgatgtaat caatcagtgc atttttctta tcgagagttg ggattttact agcctaattg
     2401 atggcttttt gatacaataa ttcaaataaa ggaggagact gtatggattt agatattatt
     2461 cgtcaagaaa tcgatcaaat cgacgaccaa attgtcaaac tgttagaaga acgaatgcat
     2521 ttagttgagg gggtggttgc ttataagaaa gcttcaggta aaccgatttt agatactaag
     2581 agagaagaag ttatttttga aaaggttagg agtcgtgtag aggacaagcg ctatcaggag
     2641 actattgtcg cgactttttc gtacatactc aaacgttcgc gtgattatca ggatcaaaat
     2701 atcaaatgaa aaaagaacaa ttttatccgc taggaatttt tctagctgct atgttgggcg
     2761 gacttgtccg atatctagtt tccacctggt taccagccag tccagacttt ccttggggca
     2821 ctctctttgt caactatctg ggaattttct gcttgatttt tcttgtcaag ggctatctgg
     2881 tctataaggg gactagtaag ggcttgattt tagcactggg gacgggtttt tgcggaggtt
     2941 taacaacttt ttccagccta atgcttgata ctgtgaagct gcttgataca gggcgttatt
     3001 ttagtttagt cctgtatttg cttttgagta tcggtggagg cctgctttta gcttactatt
     3061 tggggaggaa gaaatggtaa tcgtctatct tgcaatcgcc tgtggcttgg gagcactcgt
     3121 acggtatttc ttttctcgct ataatcaagc ttctaaattg ccactcggaa cgctcatagc
     3181 taatctttta ggttgttttt taattggagt attctacaat catgtagagt ctaaggaagt
     3241 atatgctatt ctagcaacag gattttgtgg cggtttaaca actttttcga ccttgaatga
     3301 cgaacttcaa agactgctaa gtgataagaa ggtcttttat tcttacctga ctttgactta
     3361 cataggtggt ttggttgcga tttttttagg aattttgcta taaatttctt tacttttttt
     3421 tagaaatttg gtaaactata tcttgtgtgt aatggacgca caaaaataca gtttatccgc
     3481 tgaggaagat tcctcaagat tgacaaagat aggagaataa aatgaatcca ttaatccaaa
     3541 gcttgactga aggtcaactt cgtacagata tcccatcatt ccgtcctggt gacactgttc
     3601 gtgtacatgc gaaagttgtc gaaggtaacc gtgaacgtat ccagattttt gaaggtgttg
     3661 ttattgcacg taaaggtgct ggcatctctg aaaactacac agttcgtaaa atctctaacg
     3721 gtgtaggtgt tgagcgtatc ttcccaatcc acactccacg tgttgaaaaa atcgaagttg
     3781 tacgttacgg taaagtacgt cgtgcgaaat tgtactactt gcgtgctctt caaggtaagg
     3841 cagctcgtat caaagaaatc cgtcgttaat tcgactaaaa aactctgctt tttcagcaga
     3901 gtttttatct agctccctta gttcaatgga tataacaact ccctcctaag gagtagttgc
     3961 aggttcgatt cctgcagggg gcatgtaatt agatatcaaa gaagtttgtc aaagagtctt
     4021 tgatattaaa agaacgcata atatagggga ttgtctccat aatattatgc gttttattat
     4081 tgaaaaattt gggcaatcat cagataaaat tgagactata tcgagtatat aaatgtttgt
     4141 atagtcaatt tattcaaaat cgtcaagttc taaattattt aaaggactat aacattcata
     4201 tttctttaag taattgttta tttcttcagc agtggaacga ggtaaattaa ctcttaaata
     4261 gtcaatatct tccttagata aaaaatgatt tgcattcaaa attgagaagc gaaataatgc
     4321 ttcatcaaaa gcaaaatcat aatcgtcatc agataatgat tccattaatg tttgaatatg
     4381 ttttagtgag tagtcaggta tcgaatcggg ataatatact ggataatcag tggctgaaaa
     4441 attgttttct aatcctgaaa tagtaattat caaagattct atgtaatata ttaaagcatg
     4501 tttaatatta ccttcttgtt ccaaatgtct tccctgagcc tttcgtgtgt tagataagca
     4561 tccaaaatct cctgatacag tattcctatg agcttgttta tttaagagac tccattttat
     4621 atcaccaaaa gttgctttaa aagagatatt gtttttttct ttacaataat cttccatact
     4681 tatgtcttta tcatagtatg ctttgatata gtcactatgt tcgataataa gattttgtgc
     4741 ttcttttgtt agtttaaatt cgaacggaat atctaaattg tcaatgttaa cattattaat
     4801 tattcttgta attaattctg ctttttttcc agaagtagct aaattatgtt tagataatat
     4861 agtttttaat tctactactg taagatatga taaagtctta tttttagtga agtatcctaa
     4921 tttgtataat tgattgtgtg tagattcagg gtcaatttga agagagtatt taaaatatct
     4981 tgggaaatta taatttctcc ctgttttttg agtccaatct atgagtatga gttgcccagg
     5041 agtaaggcca cattctaatt cgtttaggta aaaattgtta caatcagaat ttgtgtctct
     5101 attatgatta ttttgtttta aattaaatag tttgctaaaa aaattcattg gattttattg
     5161 ctaatcaatt cttattgaaa aatgatactt ttacagtacc catgttcgga tggcatgggc
     5221 aacgccggat tcgtcatttg ttttggtgat gtatttggcg atttttttga tttctggatt
     5281 tccattttcc atgacaacgg ggtttccaac gacttccagc atgggacggt cattttcttc
     5341 atcaccgatt gccatggttt catctttggt caatccgagt ttttcagcca agtgagtaat
     5401 ggctgaaccc ttgtctacat tctttttaag gagttcgagg tagaaaggag cagatttgtt
     5461 gatggagtag cgctcgtaaa attctgctgg aattttttca atcgcagcat cgagaatttc
     5521 tggttcatcg ataaacatac atttaacaat ttctttgcca gccatttctt caggggtacg
     5581 gtagaagata ggcatgctga cgagggttga ttcgtgtaca gtgtattttc cgatattgcg
     5641 atttgcagta tagataccgt ccttggtaat ggcatgcatg tggacaccga gcttgcgact
     5701 gaggaattcc atatccagat aatcctcata ggtcaaggat tcgctgataa tctcatggcc
     5761 agtagcagtt tcttggacaa gggcaccatt gaaggtcacc acatagtcac cttggtctct
     5821 caactgcaag tcgtccagaa gtttggcaac acctgcgatg gggcggccag ttgcaatcac
     5881 gactttgaca ccagcttctt tggcatcttg gatggcagaa aagacttcag gagtgatttc
     5941 cttttggctg ttgactaggg ttccgtcaat atcgacggca attagtttaa tactcataaa
     6001 attcctcttc tagtttttat ttggggtaaa atgatcgttc tcaatcaagt gtaaaaattg
     6061 ctgggtaatg cttgcgaaga tgctgttttg gtctaacatt tctttaggga aatagaaacg
     6121 attatctccg tggcgactgc cagcaaggga ttggacgata ggagacaggc tagagagttc
     6181 ggccagttct ccattttttt gtaaaatctc aatctgtgtc cgtggatttt gagattcggg
     6241 acgatagata tcataaggga ggtcaaagtt cttatgaatg gcagtatagt agtcgggatc
     6301 aaagccgatg tcctcaacca attttctcat gctagtaagt tgatcttggt cctcttgtga
     6361 aaaggtaatg gatttaaaga ccttgcggtt gacaaagcgt tgagataaat ctgcaagaat
     6421 tttgtcagga ctagtcatcc aaagctggaa gtaggtattc atcacgccat catccagagc
     6481 cagatagtca gtcaaggtca catttttttc gaagaaaggc aggagatgtg gggaagttcg
     6541 tgcaaagaaa ttcttgtcct cagggtagag ttccttggcg cgcttgagaa gattctgtag
     6601 gagaacttcc atggcgcgtg ttgctgggtg gaaataaacc tgcatgtaca tctggtagcg
     6661 actgaggacg tagtcttcga tggcgtgcat gccattgcgc tgaaaggcga taccattttc
     6721 gacaggacga atgactcgga ggatgcgagt caggtcaaat tccccatagg atgctcctgt
     6781 aaaataggag tcgcgcaaga gatagtccat gcgatctgcg tcaatctgac tagaaatgag
     6841 ctgcacgacc tgcttattag gataggtatg gtcaatgaca ctggccacct tttctgggaa
     6901 atcaggtgcc acttgtagca ggacttggtg aatctctgtc tcaggatttt gaataatctc
     6961 ctgagtaatg gcttcatggt ctgtatcaaa gagattttca aaagtatggg agtaggcacc
     7021 atgcccaagg tcgtgtagga gagcagcggt cacggtcaag agagactcgg caggattcca
     7081 ttcctcagga tatttttctt cgaaaatctc tgtgatgcgt cgtgcaattt catagactcc
     7141 tagacagtga gagaagcgac tgtgttctcc accgtggaag gtataactgg aagttcccag
     7201 ttgtttgatc cggcgcaaac gctgaaattc ttttgtatta atcaagtcat agatgatttg
     7261 attattgaca tggatgtagt tgtgaactgg gtcacggaat actttttcgt tcatatgacc
     7321 attatagcaa aatcctgctc tttttggtaa aatagtagga caagagacaa gaaagagggc
     7381 ctgatgtgaa gattcggatg cgaaatacaa ttcagtttga tgagcagttg gaagtgattg
     7441 accagcttta tgatgtggaa gtgcatgaaa aaggagatta tagctacctg cttttctata
     7501 atgaggaaaa ggaaaaagta gtgattaaat ttcatggtca agaacttatg atgagccgat
     7561 tttctaatcc caagaccatt atgcgctttc taaaggatag cgatagttta gcctatattc
     7621 ctacacctat gggcatgcag gagtttatca tccaaacgag ccattatcaa gttgataggc
     7681 aaaagattga actagattat caactacaaa atcaagaggg acatcctttt gccagctatc
     7741 aattggaaat tacttggggc taggctcatg tctttttcaa atttagctat ctatcttctt
     7801 ggatcggctt cctagtgtgg tagattaggc taatttttgg tataataaaa gttatggaaa
     7861 tcgaaaaaac caatcgtatg aatgcgctct ttgaatttta tgcggcgctt ttgacagata
     7921 agcaaatgaa ttatatcgag ctctactacg ctgatgatta cagccttgct gaaattgccg
     7981 aggagtttgg tgtcagtcgt caggctgtct atgacaatat caagcgaaca gaaaagattc
     8041 tggaagatta tgagatgaaa ttgcacatgt actcggacta tattgtccgc agtcagattt
     8101 ttgatcagat tttggagcgc tatcccaagg atgactttct gcaggagcag atagaaattt
     8161 taacaagcat tgataataga gaataagagg aagaaaaatg gcatttgaaa gtttaacaga
     8221 acgtttgcag aacgtcttta aaaatctacg taaaaaagga aaaatctctg aatctgatgt
     8281 ccaagaggca accaaagaaa ttcgcttggc cttgctcgag gccgacgttg ccttgcctgt
     8341 tgtaaaggac tttatcaaga aagttcgtga gcgtgcagtc gggcatgagg tcattgatac
     8401 acttaatcct gcgcaacaga ttattaaaat cgttgatgag gaactgacag ccgttttagg
     8461 ttctgatacg gcagaaatta tcaagtcacc taagattcca accatcatca tgatggttgg
     8521 tttacaaggg gctggtaaaa caacctttgc tggtaaattg gccaacaaac tcaagaaaga
     8581 agaaaatgct cgtcctttga tgattgcggc ggatatttat cgtccagctg ccattgacca
     8641 gcttaagacc ttgggacaac agattgatgt gcctgtcttt gcacttggaa cagaagtacc
     8701 agctgttgag attgtacgtc aaggtttgga gcaagcccaa actaatcata acgactatgt
     8761 cttgattgat actgcgggtc gtttgcagat tgatgagctc ctcatgaatg agcttcgtga
     8821 tgtgaaagca ttggctcaac caaatgaaat cttgcttgtc gttgatgcta tgattggtca
     8881 ggaagcagcc aatgttgcgc gtgagtttaa tgctcagttg gaagtgactg gggtcatcct
     8941 taccaagatt gatggcgata ctcgtggtgg tgctgctctg tctgttcgtc acattactgg
     9001 aaaaccaatc aagttcactg gtacaggtga aaagattacg gacattgaaa ccttccaccc
     9061 agaccgcatg tctagccgta tccttggtat gggggatatg ctcactttga ttgagaaagc
     9121 ttctcaggaa tacgatgaac aaaaagccct tgaaatggct gagaagatgc gcgaaaacac
     9181 ctttgatttt aatgatttca tcgatcaatt agatcaggtg caaaatatgg ggccgatgga
     9241 agacttgctc aagatgattc caggtatggc caacaatcca gcccttcaaa acatgaaggt
     9301 ggatgaacgc cagattgctc gtaaacgtgc cattgtgtct tcgatgacac ctgaagagcg
     9361 tgaaaaccca gatttgttaa atccaagccg tcgccgtcgt attgctgctg gttctggaaa
     9421 tacattcgtc gaagtcaata aattcatcaa ggactttaac caggctaaac agctcatgca
     9481 gggtgttatg tctggggata tgaataaaat gatgaagcaa atggggatta atccaaataa
     9541 ccttcctaaa aatatgccaa atatgggagg aatggatatg tctgcccttg aaggaatgat
     9601 gggacaaggc ggtatgcctg acttatcagc tctcggagga gcaggaatgc cagatatgag
     9661 ccagatgttt ggtggcggtt tgaaaggtaa aattggtgaa tttgccatga aacagtccat
     9721 gaaacgtatg gctaacaaaa tgaagaaagc gaagaagaaa cgcaagtaag acaagagatt
     9781 gatgcaaatc tcatttgatg agaaaataaa gtaaaaattt ctatgataaa acgtacagta
     9841 tcaaggtttt agaatatctg atattatacg ttttttgatt ttaataattt tgttaagaca
     9901 cttttattat ggtatacgaa aaatccactc agctgtctga gtggattagg tgtatttaga
     9961 ctcttagtct ttattttcgt atggcaagat caagttcaag atgattcctg tcatggctga
    10021 aagggcagta cctgaaagtg taactggacc aagtttaagg atagctcctc caagtccaag
    10081 aaccaacata gcacttgcga tgatgaggtt tcgcatttga gcgaaatcaa cacgttcttt
    10141 aatcaagact ttcaaaccat tgctggcgat aaccccatag agaaggattg acataccacc
    10201 aagtacagcg tttggaatag ttgaaatcaa ggcagtgaat ttaccaagga agctgagggc
    10261 aatcgcgatg aaggcagcgt tacggataac tgagacagaa gcgatacgag tcataccgat
    10321 aacccctgta ttttctccgt aagttgtatt ggctggtcca ccaaggaagg cagaaacaga
    10381 agttgcgata ccgtcaccaa gaagagtacg gtgaagacct ggttctttta agaattgacg
    10441 accacagatt tgacccaaaa cagtatggtc tccgatatgt tcagaaattg ttacgatagc
    10501 gattggcaag atagcgatgg cttctggacc aaagtaaaga ttgtactctt taaaggcacc
    10561 acctgtgcta aatggcaagt agaaaccagg aatttcgaac cagttggctt taagaactgg
    10621 tgtaaagtca accaagccaa gagttagtgc gaaaaggtaa ccaccgataa tggcaaagag
    10681 gaatggaatg attcgtagga agccttttcc ttttgtattg ataaaggcag caattaggaa
    10741 agtaacaacg gctaccagag catttttcca atttccgtct gctacaagac ctgcattggt
    10801 aacagctgaa cctgcaagtc caagaccgat aacgatgatc ataggaccga taatgattgg
    10861 tggcaagagt ttatcaatcc attttgttcc tacaaatcgg atgctggtag caacaaggac
    10921 atagaccaaa ccagtcaaga taacccctgt ttgggcagca gatacatccc cccccatttc
    10981 tttcatagcc agtgacatag ctgtgataaa ggcaaatgaa gaacctagat aaactggaac
    11041 tttaaaacca gtagcaatca tgtagatgag tgttccaaca cctgaagcaa aaagggcaac
    11101 agatacaggc attcccaaaa tcaatggtac caagatggtc gcaccaaaca tggcgaaaac
    11161 gtgttggaaa ctaaggagaa ttccttttcc agccgaagga cgttggtcaa cgtctagtaa
    11221 caaatcaaca gttgattctt gtttcatata aacctcactt ttgggcatca aaaaagagcc
    11281 cattatttta cagcaatagg ccctcagagt aagacttctt taaaatttag attttaaaga
    11341 gttttaaata tttctgcgtc ttcgtcacct cacgggatga cattaaaaac ctttgcttag
    11401 gatagtatag cagaaaaaaa tgattttgta aatcattttt tcccgagcct agaaataaaa
    11461 gagcgaggct gattttgtaa atcatttttt cccgagccta gaaataaaag agcgaggctg
    11521 attttgtaaa catttgttta ctaaaaaatt taaagtgggc gtttatttgg cataccagcc
    11581 ttacgcggat atttatttgg tgtttctttt ttcttttcta ccactgtgat atagcgcgga
    11641 tctctattcg gtagggcgta gctgagattg tcttcgacct tactaaaaag gagattgagg
    11701 gcattcttag cttctaataa ttcctcaggc gcattgctgg ccttgagtgc caatagtttt
    11761 ccaccaacct taaggtaggg aatggtcaat tcagatagga cctgcatacg ggcaaccgca
    11821 cgagctgtta caaaatcata ttgagcacgg aagttcttgt cttgggcaaa atcttcggca
    11881 cgtccgtggt agaaatgaac tccgttcaaa tccagttctt gagccaagag ttgtaggaag
    11941 ttgatgcgct tattgagtga atcaataatg gtcacatcta actccggata gagaattttc
    12001 attggtagac taggaaatcc tgccccagcc ccgatatcaa gaagtttgat agtttcattg
    12061 ggaatcaaac cttgaagaat gggtgcaatc gaatcgtaaa aatgtttgag ataaacttct
    12121 tccttgtccg taatcgccgt caaattaatc ttctcattcc actcgaccaa gagctcaaaa
    12181 taacgttcaa attgttcttt ttgctggtcc gaaagtggaa gattctgctc ggcaagcaag
    12241 ttgtaaaatg tttttggttt catagttatt tccttcttta gtatcatctt attttaccac
    12301 aatcatagaa aatttgatat actggtacta atctaaaagc agaaaggact tatattatga
    12361 cttggattat tcttggagtt atcgctctta ttgttatttt tgtgattgtt agctataacg
    12421 gtttggttaa aaatcgtatg caaaccaagg aggcttggag tcagattgat gttcagttga
    12481 aacgtcgaaa tgacctcttg ccaaacttga ttgagactgt aaaaggttat gccaaatatg
    12541 aaggttctac ccttgaaaag gtggcagaac tacgtaacca agtggcggca gcgacttcac
    12601 cagcagaagc tatgaaagcc agtgatgccc tcactcgtca ggtttcaggt atttttgcag
    12661 ttgcagaaag ctatccagat ttgaaagcta gtgctaactt tgttaaattg caagaggagt
    12721 tgacaaacac agaaaataaa atttcttact ctcgtcaact ctataacagt gttgtcagca
    12781 actacaatgt aaaattagaa actttcccga gcaatattat cgctggaatg tttggattta
    12841 aagcggcaga tttccttcaa acatctgaag aggaaaagtc ggttcctaaa gttgatttta
    12901 gcggtttagg tgactaagat gttgtttgat caaattgcaa gcaataaacg aaaaacctgg
    12961 attttgttgc tggtattttt cctactctta gctcttgttg gttatgcggt tggttatctc
    13021 tttataagat ctggacttgg tggtttggtt atcgcactga ttatcggctt tatctacgct
    13081 ttgtctatga tttttcaatc gacagagatt gtcatgtcca tgaatggagc gcgtgaggtg
    13141 gatgagcaaa cggcaccaga cctctaccat gtagtggaag atatggctct ggtcgctcag
    13201 attcctatgc cccgtgtttt catcattgat gatccagcct taaatgcctt tgcgacaggt
    13261 tctaatcctc aaaatgcggc tgttgctgcg acttcaggtc tactagctat catgaatcgt
    13321 gaagaactag aagctgttat gggacatgaa gtcagtcata ttcgtaatta tgatatccgt
    13381 atttcgacta ttgcagttgc ccttgctagt gctatcacca tgctttctag tatggcaggt
    13441 cgtatgatgt ggtggggtgg agcaggtcgc agacgaagtg atgatgaccg agatggaaat
    13501 ggtcttgaaa tcattatgct agtggtttcc ctactagcta ttgtactggc acctctcgct
    13561 gcaaccttgg ttcagctcgc tatttctcgt cagagggaat ttctggcaga tgcatctagt
    13621 gtcgagctga ctcgcaatcc ccagggaatg attaatgccc tagataagtt ggacaatagc
    13681 aaacctatga gtcgccacgt cgatgatgct agcagtgccc tttatatcaa tgatcctaag
    13741 aaaggtgggg ggttccaaaa actcttttat acccacccac ctatctcaga acggattgaa
    13801 cgtttaaaac agatgtaaaa gaatccagag gtcgtctctg gatttttgct atgttgcaaa
    13861 tttataaatc ttctaaatta actagcttca aaccgtgttc tgtcatgcga tagatgatcg
    13921 agcagacttc ttttaagaaa cgacggtcat gcgaaacagt gatgagaccg cctggatagg
    13981 ttgcaaagag ttttctgatt tggggttgag aagtgggaga aaagtttcgt gtgggttcat
    14041 ccagcaggag aaagtttggt ttgcgcagaa ctagatccaa aagcaggagt tttccctgtt
    14101 gtccgccaga taaggagcga atttgatgct gcatttctgg ataactgaaa ttgagactgg
    14161 ctaggtgaga ttggattttc tgaagttcct ctttttcccc agttttgctg atataagcta
    14221 ttgaggataa atccaattgc agttttttgt ggtaatcttg tggcataaaa ccaagtgaaa
    14281 tctctctttt atcattcaga agttgctgta atttggctaa cagagttgat ttcccaacac
    14341 catttgggcc gatgataccg attttttctt ggccacggac agttagttgc agttcctgag
    14401 ccaaaacacg gtcgtcaatg gacaaatttt ctttttccag ttggactaag actttagaag
    14461 ctggtaatgg ttggatgtct gaaaagaaaa gttggatttg ttcctcttca agtggctttt
    14521 gagtcatgga ctgagctgtc ttttcgtagc gtttttcttg tgagaggaca gttttcatct
    14581 ttttagccaa taggcgaccg gcagtactat ctttggtagc tcgaagcgca gtttctacat
    14641 tttgcttaac tctccgatgt ttttccatgg ttttatcgta ggctctttgg ttgttagcag
    14701 cttgctgact ttgtttggca aaattagcct ttctctgctc actatagcta tcatagtcta
    14761 aatgctctac tagcgtttcc gcttctttac ggtgtttgac cagtcgcaag tgaacaatag
    14821 tgtctgccgt ttcagaaaga aagtcttcat catgggaaat gaaaataacg gtttgcctgg
    14881 tcttttgaat ctggcctttt agccaatcaa ctgtctcaag gtctaggtca tttgaaggtt
    14941 catctaaaaa tagaatctca aagggtttgg ctaactcatg gataagctga attttcaaag
    15001 cttcgccccc tgatagattg ccaatctctt ggtcacttgc gaaacgattg ctatcaaaat
    15061 gcaattcctc cgccaaacga tagaggatac tgtagtctaa atcaatagaa tctaaaaaga
    15121 agtagtcgtg taaagttttc ttttttaggt cctcagggac tttttgagga atgtaggcca
    15181 gtgactgata atcagactgg atgtctccct tgatagtgaa atcagacaaa tcttccccca
    15241 ttaaagtttt aagtaaggtt gatttaccat ttccttcttc gccaataata gctacctttt
    15301 ccccgtcttg tatggtcatg cttaggtcag agacaaggtc tcgtaaatct ttgttttgtg
    15361 tgatggtcag gtgattgatt tttatcatac tattgccctt tctagaatgt cgatagtgca
    15421 taacaaaaag ctctacttta cctagtagag cccaaagtct atgtcaaaaa aactctatta
    15481 acatgccaga aaaagagcat aaaagagcac acaaaaagag acaaaaacaa gatctactaa
    15541 ataaaggttc tttatttgat agacttagtt gttcatgtct cccttacctc cgagtattag
    15601 tatctttata ctatactttt aaggaaattt tgtcaacaga aaactggaaa ttctatgctc
    15661 taaaatccaa aaacaggtcc atagagactt agtacgtgtt tgacatgctc gtaatggatt
    15721 ttatcatagt ttcgccaagc agtgcgtgct tgatcgttta gttttaggct acccagtcca
    15781 atcagaggac tggtgggttg gtaaaatttc tcaagatcaa ttaagatact gttgttcaac
    15841 ttttccgttt ttttgagctc ttgcatagta gtgtttagca gctcttgtag tcgaatatca
    15901 tctgccgtac cctgtttaca gttttggtag cttttattta acttggatag gagttgaatg
    15961 agtttcttgt cttccatgtc ttccatatga gcatcctcct tgatctgatg tactctttcc
    16021 ctatagtata gcactaaaaa ataaaactgt catagtaaat atgttaaaat tttgaatttt
    16081 aattacaaag tttggtgtgc tgatttgtag ccttttcatg gtataatcaa gagagtaaat
    16141 ctttatggag gaagtatgaa attaaatatt caagaaattc gtaagcagtc tgaaggtttg
    16201 aactttgaac aaacgttaga tttagttgat gacctgcgtg cacgtaatca agaaatttta
    16261 gatgtaaaag atatccttgc agttgggaaa gtacaatatg aagaccgtat gtatttctta
    16321 gattatcaac tatcttatac cattgttctt gcttcgagtc gcagtatgga gccagttgag
    16381 ttagttgaat cttatccagt cacggaagtt ttcatggaag gcgcaactaa ccagctagat
    16441 caagaagttt tagatgatga cttggtcttg cccattgaaa atggggagct tgaccttgct
    16501 gagagtgtat cagacaatat cctgctaaac attcctatca aggtcttgac ggctgaagaa
    16561 gaagctggtc aaggatttat ctcaggaaat gactggcaaa tcatgacaga ggaagaatac
    16621 caagctcaac aagcagtaaa gaaagaagaa aacagtcctt ttgctggctt acaaggacta
    16681 tttgacggag atgaataatg gtcttgtcaa aaaaacgagc acgaaaggtg ctagaagaaa
    16741 tcattgccct cttcccagat gccaagccta gtcttgattt taccaatcat tttgaactcc
    16801 tggttgcggt catgttatca gcccagacga cagatgcagc ggtaaataag gccacaccag
    16861 gtctctttgt tgcctttcca acaccccaag ctatgtctgt agcgacagag agtgagattg
    16921 cttcacatat ttctcgcttg ggattgtatc ggaataaagc taaattcctt aaaaaatgtg
    16981 cccaacagtt actagacgat tttgatggtc aagtccctca gacacgtgaa gaattggaga
    17041 gtttggcagg tgttggtcgc aagacagcca atgttgtcat gagtgtagga tttgggattc
    17101 cagcctttgc agtggatact catgtggagc gtatttgcaa acaccacgat attgtcaaaa
    17161 aatcagcgac gccacttgag gtggaaaagc gggtcatgga tatcttgccg cctgagcagt
    17221 ggttagctgc ccatcaggcc atgatttatt ttggaagagc catttgccat ccaaaaaatc
    17281 cagagtgtga ccagtaccca caattatatg attttagcaa tttgtaagat gctacattga
    17341 aactttttgc ttgattttaa gcatgctttg tgctatagta aatgataact aaatattcct
    17401 ttaaacctgt cccgtgaggc aggcaaggag cgcgataaag tagaagggtg aagtctatac
    17461 tgtttgcagt agggctcgct tggctataaa tttcaagtct ccttgtttaa ggagactttt
    17521 ctttttggag gtttgtcatg aaaacaaaag aagttgtaga cgaattgacc gtcaaacgag
    17581 cgattacgcg tattacttat gagattatcg aacgcaacaa agatttgaat aagatcgtct
    17641 tggctggtat taaaactcgt ggtgtcttta ttgcccaccg aatccaagaa cgtttgaagc
    17701 agttagaaaa tctttcagtt cctgttgtgg aattggatac taaacctttc cgtgatgatg
    17761 ttaaaagtgg agaagatact tctttggttt ctgtcgatgt gacagaccgc gaagttatct
    17821 tggtggatga tgtgctctat acaggtcgta ccatccgtgc tgctattgat aatattgtcg
    17881 gtcatggtcg tcctgcgcgt gtgagtttag cagttctagt cgatcgtgga catagagaat
    17941 tgccaatccg tccagattac gttggaaaaa atatcccaac cagtcgttct gaagaaatca
    18001 tcgtagagat gacagaactt gatgaccaag acagagttct gattactgaa gaagcttaga
    18061 aagttaaagg agtagccatg tcagaaaatc aacaagcatt gaaccatgtg gtgtccatgg
    18121 aagacctcac tgtcgatcaa gtaatgaaat tgatcaagcg aggaattgag tttaaaaatg
    18181 gagcccagct tccctatgaa gaccatccga ttgtttccaa tctcttcttt gaggattcta
    18241 cacggacaca taagtccttt gaagtcgcag agattaaact tggattggaa cgacttgact
    18301 ttgatgtgaa gactagttcg gttaataagg gtgagacact ttatgacacc attttgactc
    18361 tgtctgcttt aggagtggat gtctgtgtga ttcgccatcc agaggtcgac tactatagag
    18421 aattgattgc tagtccaacg attacgactt ccatcatcaa tggtggagat ggttcgggcc
    18481 aacaccctag ccagagcttg cttgatttga tgaccattta tgaggaattt ggccactttg
    18541 agggtcttaa agttgctatt gcaggtgact tggaccactc acgcgttgcc aaatccaata
    18601 tgcagatttt gaaacgcttg ggagctgaac tctttttcgc tggacctgag gaatggagaa
    18661 gtcaagagtt tgcagactat ggaaagtttg taaccattga tgaaatcatt gatcaggttg
    18721 atgtcatgat gtttctccgt gtgcaacacg aacgccatga tagtggagct gtattttcaa
    18781 aagaagacta tcatgcccaa catggcttga ctcaagaacg ttacgatcgt ttgaaagaaa
    18841 cagcaatcct catgcaccca gctccaatca atcgtgatgt agaaatagca gaccacttgg
    18901 ttgaagcacc aaaatcacgg attgtccaac aaatgaccaa tggtgtcttt gttcgaatgg
    18961 caatcttaga atccgtacta gcgagtagaa acgccaacta aaacacaaga cgttaaaaga
    19021 cgccagtgag cgtccacgag aggtgaaaat atgacaaaaa gaattctagt attagaagat
    19081 ggcacagttt ttgaaggcaa ggccttcgga gcagatattg atgtaacagg cgaaatcgtc
    19141 tttaatacag ggatgaccgg ctaccaagaa tccattacag accagtctta taatggacaa
    19201 atcttgacct ttacttatcc tttggtagga aattatggta ttaatcgtga tgattatgaa
    19261 tccattattc caacttgtaa gggagtcgtt gtttttgaag aagcgcgtag agctagcaac
    19321 tggcgcaacc aaatgacctt ggatgaattt ttgaaagcca agaaaattcc agggatttca
    19381 ggaattgata cgcgtgctct taccaagatt atccgtaagc atggtactat gcgtgcaacc
    19441 ttgacccatg ttggggacag tatggaccat gtgacggacc agctccaagc aacagtttta
    19501 ccgacagaca atatcaaaca ggtttctact aaaacgtctt atccagctcc aggagttggt
    19561 ttgagcgtgg tgctagtgga ctttggtctc aagcactcaa tcctacgtga actttctaaa
    19621 cgcaactgta acgtgacagt tgttccttat tcgacaacgg ctgaagaaat tctccatctc
    19681 aatcctgatg gagttatgtt gtcaaatggt ccaggtaacc cagaagacgt tccacaagca
    19741 ctcgacatga ttcgcggtgt acaaggaaaa attccaatct ttggtatttg tatgggacac
    19801 caactctttg caatggcaaa cggggctaag acctataaga tgaagtttgg ccaccgtgga
    19861 ttcaaccatg cggtacgtga aatcgcaaca ggacgagtag acttcaccag ccagaaccat
    19921 ggttatgcag tcagccgcga ggatttgcca gagcacttga ttattaccca cgaagaaatc
    19981 aatgacaagt cagtggaagg tgtgcgccac agataccaac ctgctttctc tgttcaatac
    20041 cacccagatg cagctcctgg gccacacgac gctagctacc tatttgacga gtttatcgag
    20101 atgatggaag tttttaaaca atcaaactaa gaatgagtaa aagctcgtcg gagaatttat
    20161 gtaactgaac atggacggaa agctcagaat ttagagaaac caacttggat tgtcaatcct
    20221 tccttgattt cctaaaattc aatcgctttc tagtcgtcct ttgtatctta tttaatgtcg
    20281 ccctgagagg cgacgaatag aaaggagaag atacattgtt cgcggaagtg aacacgccct
    20341 aagaactgtg tgaaaaagat aaacatcgtc ttgacgctga aggcgtctgc gccgagtttc
    20401 ctattttcac tgtgttcttt acgggctttg tatcataaac tatgcctaaa cgtactgata
    20461 ttcaaaaaat tatggtgatt ggttctggtc cgattattat tggtcaggct gctgagtttg
    20521 actacgctgg gactcaggct tgcttgtcgt tgaaagagga aggttatgag gttgttttgg
    20581 ttaactcaaa tcctgcaacc atcatgacgg acaaggaaat tgctgacaag gtttacattg
    20641 aaccgattac acttgagttt gtgacacgta ttcttcgtaa ggaacgtcca gatgccttgc
    20701 taccaacact cggtggtcag acaggtctca acatggccat ggaattgtct aaaaatggta
    20761 tcttagatga gcttggcgtt gaacttctgg gtaccaaatt atctgccatt gaccaagcgg
    20821 aggaccgtga cctctttaaa caattgatgg aagagcttga acaacccatt ccagaatctg
    20881 aaattgttaa cacagtagaa gaagcagttg cctttgcagc gacaattggc tacccagtca
    20941 tcgttcgtcc agcctttacc ctcggtggta ctggtggtgg tatgtgtgcc aacgagaaag
    21001 aattgcgtga aatcactgaa aatggtttga aattgtcacc tgttacccaa tgtttgattg
    21061 agcgttcgat tgccggtttc aaggaaattg aatacgaagt gatgcgtgac tcagctgaca
    21121 atgccttggt tgtttgtaac atggaaaact ttgacccagt tgggattcac acgggggatt
    21181 ccattgtatt tgcccctgcg caaaccatgt cagactatga aaaccaaatg cttcgtgatg
    21241 cgagcttgag cattattcgt gccctcaaga ttgaaggtgg atgtaatgtt cagctagctc
    21301 ttgatcctaa cagcttcaag tattatgtta tcgaagtaaa ccctcgtgta tcacgttcgt
    21361 cagcccttgc ttctaaagcg acaggatatc cgattgctaa gttggctgcc aagattgcag
    21421 taggtttgac cttggatgag gttataaacc cagttacagg ttcaacctat gccatgtttg
    21481 aaccagccct tgactacgta gttgctaaga ttccacgttt cccatttgac aagtttgaaa
    21541 agggtgaacg ccgtctcggt acacaaatga aggcgactgg agaagtcatg gcaatcggtc
    21601 gtaacatcga ggaatctctt ctcaaggcct gccgctccct tgaaattggg gtgcaccaca
    21661 atgaaatacc tgaacttgca gcagtttctg atgatgcctt gattgaaaag gttgtcaaag
    21721 cccaagatga ccgtctcttc tacgtatcag aagcaattcg tcgtggctac acacctgaag
    21781 aaattgcaga gcttacaaaa attgatatct tctatcttga taaactcttg catatctttg
    21841 aaattgagca agaattgggt gctcatccac aagatctaga agttttgaaa acagccaaac
    21901 ttaatggttt ttcagaccgt aagattgctg aactctgggg aacgactgat gatcaagttc
    21961 gccaacttcg cttggaaaac aagattgttc cagtttataa gatggtagac acttgtgcgg
    22021 cagagttcga ctccgaaacg ccatatttct attcaaccta tggttgggaa aatgaatcta
    22081 tcagatctga taaagaatct gtacttgtcc taggttcagg tccaatccgt attggtcaag
    22141 gggttgagtt tgactacgca accgttcact ctgttaaggc tatccaggca gctggttatg
    22201 aagctatcat catgaactca aacccagaga ccgtttcaac agacttctct gtatcagata
    22261 agctttactt tgagccattg acattcgaag atgttatgaa cgtcattgac ttggaacaac
    22321 caaagggagt tatcgttcag ttcggtggtc aaacagccat caaccttgcg gagccattgg
    22381 caaaagcagg tgtgaccatc cttggtacac aggttgctga cctagatcgt gccgaagacc
    22441 gtgacctctt cgagcaagct ctcaaagaat tggatattcc acagccacca ggacaaacag
    22501 ctaccaatga agaagaagca gctcttgcag ctcgcaagat tggcttccca gttcttgtcc
    22561 gcccatctta tgtacttggt ggacgtgcca tggaaatcgt tgaaaacgaa gaagaccttc
    22621 gttcttacat gcgaactgct gttaaggcta gtccagacca cccagttctt gtcgactctt
    22681 atatcgttgg gcaagagtgc gaagttgatg ccatttcaga tggtaaaaat gtactcattc
    22741 ctggtatcat ggagcatatc gaacgtgctg gtgtccactc aggtgactca atggctgttt
    22801 acccaccaca aaccttgtcg caaaaggttc aggagaccat cgcagactac accaaacgct
    22861 tagcaatcgg tcttcactgc cttggaatga tgaacatcca gtttgttatc aaggatgaaa
    22921 aagtctacgt tattgaggtc aatccacgtg ccagccgtac tgttccattc ctatctaagg
    22981 taaccaatat tcctatggct caagtagcga ccaaactcat tcttggtcaa agtttatcag
    23041 aacttggcta ccaaaatgga ctttaccctg aaagcacccg tgttcatatc aaggcacctg
    23101 tcttctcctt taccaaacta gctaaggtag acagcttgct cggtcctgaa atgaagtcaa
    23161 caggtgaagt tatgggttct gatgctactt tggaaaaagc tctctataaa gcctttgaag
    23221 cttcttatct acacttgcca acttttggta atgtcgtctt taccatcgct gatgatgcca
    23281 aagaagaagc cttgaacttg gctcgtcgtt tccaaaacat tggttatgga atccttgcga
    23341 cagaagggac agcagccttc tttgctagcc atggcttgca agcccaacct gttggtaaga
    23401 ttggtgatga cgataaggat atcccaagtt ttgtacgcaa aggaagaatt caagctatca
    23461 ttaacacagt aggaacaaaa cgaactgctg acgaagatgg tgagcaaatt cgtcgttcag
    23521 ccattgaaca cggggtgccc ctcttcacag cgctagatac agctaatgcc atgcttaagg
    23581 tacttgaaag tcgtagcttt gttacagaag cgatttaaat agaaaaataa gatatagcag
    23641 actgaattta gaacagtaca caggaatact aaaatatttc tagaaattaa tttgaatttt
    23701 ctaattgatt tgttcgcatc ttatttcaat ctactataga aaaaagtctt taaaattata
    23761 aaacgcatca tatcaaggtt tttcaaaaac cttgatatga tgcgttttat tgtgggaata
    23821 tgtatttcat tttctactaa aattatgttt ttgaataacc tctatcttag tagtttgtat
    23881 aatccccctc aatcagtttt tgcgataagc tttaatgcta tgactatacc actcttgcat
    23941 ttcttttgat ggtggtgtca tataatcgcc atacatctgg gttaaaaatt ggtcatattt
    24001 tttgggaaca ggcaacatac ggccctcaaa ctcagttaaa atcagttctt taaaggtatc
    24061 aactgggaag atttctttca tcccttcctt accgatccca actcctcctt catattgagg
    24121 aatgttggtt acagcatttt tgactagttg atcaattttc ttgtaaaagt agcgaggatt
    24181 gacaaatcgg agagcgtacc agctacataa tctaagaaaa tcttttagtt tgctatcacc
    24241 gtgaactgct cgtgattttt tgatgtaagc tagttgacga agggccacat acttatagct
    24301 cttgtcgaca atgctcaagt ctgtaaattg atcaattggg aagacatcga tgaaaaggct
    24361 ggtatcatga cgcttgtact taacatggtc ttctataaca gtagaagtat ccaaaatcga
    24421 tgcgaaatta tggaagtacc aagaagatgt atcgtaggaa agaaccttgt agcgagggtg
    24481 attttcttct tcaataatct tcagtaaacg ctcataatcc tcacgataaa gggaaatatc
    24541 aatatcatca tcccaaggaa tcataccttt gtggcggatg gctccaagca tggttccata
    24601 actgagaaaa taaggaatat catgtttctt acaagtctca tcaatatagt ccagcagggc
    24661 tagttgaatt tctttaattt cttttttttc taaatattgc atcctaatcc tccaatttat
    24721 aagcgtgaaa ttcatgactg tagaagcgtt tttcttctgg tggtagggtc atataatctc
    24781 cataaaattg tgtcaaaata gtatcaaatt tttcaggtgc aggaaggctt aaattctcaa
    24841 agggtaaatc gattgtttta tcaaaggtag cacttgggaa gacttccttt tccttaaatt
    24901 ttgaaggaat aaaagccata tactgcccat tttcacgact atatttttga atttctttct
    24961 cgattttatt tgcaaaataa cgaggagaaa ccagtcgaag gagcaaccaa aaggctgttc
    25021 gtatccaatc ttttaaaagg ctatccttat agacaatatt tttatgttta ctgaaagaca
    25081 gcagtttgaa gctttctagt ttataacaag tatcaatgac cttaggatca tcaaagcgat
    25141 ccatagggaa aatatcgata aagataccag actcataggt ttttgtattt cgagtatcaa
    25201 taattttagt cgtactgtcg gttatcttga taaagttgtt aaagtagttc ttatcagttt
    25261 ctaaggatag gagcttatac ttgctttttt ccttttgaaa aatgttaata aatcgttggt
    25321 agtcttctct aggcatggat aaatcaatat cgtcgtccca agggataaag ccctcatgtc
    25381 gaaccgcccc aatcagagta ccgtagttaa taatatagtt gatattgtgc tttttacaga
    25441 gagtatcaat ataattcaaa atttctaatt caatttgttt ggcatcttca acggttagtt
    25501 gtttcatttt aaactcctaa gattttttaa atttattttt taaggctagg acatggttta
    25561 aaaattcata gaaaatgcta tcttttgtga agacaagtag actaatataa gagatagctg
    25621 atagcaagac aatcaaacca gtattaatca aaaatggcaa attaatgacc atatccacag
    25681 gatacacgaa attaatcagg aaataaattg ctacaaagga aagtgaaaag agagagtatc
    25741 gaacagtata gctaaagata tgtcccaagt ggatgagttg ttttctatgg atgaaaatga
    25801 tatagaaaac aagtagagaa gcctctgata acatagttgt cagtaagtag tattcgggag
    25861 ccacgatatg gttgaaaaag aggagactat tcaagcccaa attgagtagc ccagcaaaga
    25921 ctgtatagac tgtgatacgt ttttcatagc cattggtaaa gagaatttgg gaaccaagaa
    25981 tggtatctaa ggccaggata atcgtacgaa aagcgaagag agaggtcaag atgtcgcctc
    26041 cgatatattt ttcactaccg taaagtagga tggcatttgg tcctaaaacc atgagtccaa
    26101 aactcagtgg aatgataaag aagttaaaga ttcgactacc tctattaacc agagaaacat
    26161 aggcttcttt gtctcctttc cccagatagt aactgagacg aggcacactc actccaattg
    26221 cacctgttac aaccccagct ataacggtca caattcgctg agctatggta tagtaactaa
    26281 cgttgacatc aatccctgtt ttaacgagga agaggcgatc taaaaaagtg aagagcatat
    26341 tggcattggc aaagactaac atggctgtca gagggagaaa gagtggttta aaatcactta
    26401 ggtgaatctt aacaagtttg atgtctcttt taatccaaaa ataactaatc aggtagttaa
    26461 tcagcgtcga taaactcatc acaagtgtat agacaacaat atcgtgttca tttttaacaa
    26521 ataagaaaat agagaccagc atcaggatac ggatgaaggc agttttgtaa aagagaaaac
    26581 tgtaattttc cagagcttca ttgacccatt cgattgaaaa aatctgggca atgagttgaa
    26641 tccccataac aaggtagacc tttttgacga ttggattatc agtaaagaag agaggatagg
    26701 ctaggatata gacagcagtg gtcaaaatcg tacaagcgat gcacaaataa aaaagactag
    26761 aaaaggttct gttaagatct tttttgttat ccttgacatt actgatagcc cttaaaccgt
    26821 agttatagac accataagtt gcaaagggca agaaaaatga caaaatagtg tcgactgagt
    26881 tgaagtaacc atagtcagtt cggtccaaga cacgcgcgac ataggttcca gttaggatgg
    26941 gaaaaataat attcaagaca cgaattccca tgtaagatag agcatttaat tttatacttt
    27001 tcattcaatt tacctcgttt ttcattatat cataaagtta gctaataaga aatgaagggc
    27061 agtaagtcaa gtaatcactt tgaagtttca aatcttaagt tttaagtttt ctttaaggaa
    27121 agtatattat tctgaaggac tctaaaattt cgcagccatt tattagtaat tgctacagaa
    27181 ttcctagtca ttactagaaa tggactagtt tctttgaata atagaactgc ataattctcc
    27241 tattctagaa ggggaggacc agtatttctt ttatgatagg actagattgt ggtataatag
    27301 agagaataag tttttttagt aagacaaagg agaaaataga tgatttatgc aggaattctt
    27361 gccggtggaa ctggcacacg catggggatc agtaacttgc caaaacaatt tttagagcta
    27421 ggtgatcgac ctattttgat tcatacaatt gaaaaatttg tcttggagcc aagtattgaa
    27481 aaaattgtag ttggtgttca tggagactgg gtttctcatg cagaagatct tgtagataaa
    27541 tatcttcctc tttataagga acgtatcatc attacaaagg gtggtgctga ccgcaataca
    27601 agtattaaga aaatcattga agccattgat gcttatcgtc cgcttactcc agaggatatc
    27661 gttgttaccc acgattctgt tcgtccattt attacacttc gcatgattca ggacagtatc
    27721 caacttgccc aaaatcatga cgcagtggac acagtggtag aagcggttga tactatcgtt
    27781 gaaagtacca atggtcaatt tattacagat attccaaatc gtgctcacct ttatcaagga
    27841 caaacacctc aaacattccg ttgcaaggac ttcatggacc tttatggatc tctttctgat
    27901 gaagagaagg aaatcttgac agatgcatgt aaaatctttg tgatcaaagg aaaagatgtg
    27961 gccttggcca aaggtgaata ctcaaatctg aagattacaa ccgtaacaga tttgaagatt
    28021 gcaaaaagta tgattgagaa agactagtaa aatgattaat caaatttatc aactaactaa
    28081 gcctaagttt atcaatgtca aatatcagga agaggctatt gaccaagaga atcatatcct
    28141 tatccgtccc aactacatgg ctgtctgtca tgcggatcag cgttactatc agggaaaacg
    28201 tgatcccaag attttgaata aaaagcttcc aatggcaatg attcacgagt catgtggaac
    28261 cgtcatttct gacccgaccg gaacctacga ggttggtcaa aaagttgtca tgattcccaa
    28321 tcagtctcct atgcagagtg atgaagaatt ctatgaaaac tacatgacag ggacccattt
    28381 cttgtctagt ggatttgatg gctttatgag agagtttgtt tctctcccta aagatcgtgt
    28441 ggtggcttat gatgctattg aagatacggt tgcagccatt acagagtttg tcagtgtggg
    28501 catgcacgct atgaatcgtc tattgactct tgctcatagc aagcgggagc ggatcgccgt
    28561 tattggagat ggaagtttag cttttgtggt tgccaatatt atcaactata ctttgccaga
    28621 agcagagatt gtggttattg gtcgtcattg ggaaaagttg gaactcttct catttgccaa
    28681 agaatgctat attacggata atattcctga agagttggcc tttgaccatg cttttgaatg
    28741 ttgtggtggt gatggtactg gaccagctat taatgacttg attcgctaca ttcgtcctca
    28801 gggaacgatt ctcatgatgg gagttagcga atataaagtc aatctcaata ctcgcgatgc
    28861 cttagaaaag ggcttgattt tggttgggtc atctcgttct ggtcgcattg attttaaaaa
    28921 tgctatccaa atgatggaag tcaagaaatt tgccaatcgt cttaaaaata tcctttatct
    28981 agaagaacct gtaagagaaa ttaaagatat tcatcgtgtc tttgcaaccg atttaaacac
    29041 agcctttaaa acagtgttta agtgggaagt ataagtactg gaggttaatt gtggagaaaa
    29101 tcattaaaga aaaaatttct tccttactta gtcaagaaga ggaagtcctc agtgttgaac
    29161 aactgggtgg aatgaccaat caaaactatt tggccaaaac aacaaataag caatacattg
    29221 ttaaattctt tggtaaaggg acagaaaagc ttatcaatcg acaagatgaa aagtacaatc
    29281 ttgaactact aaaggattta ggcttagatg taaaaaatta tctttttgat attgaagctg
    29341 gtatcaaagt aaatgagtat atcgaatctg cgattacgct tgattcaacg tcaatcaaga
    29401 ccaagttcga caaaattgct ccaatattac aaactattca tacgtctgct aaggaattaa
    29461 gaggagaatt tgctcctttt gaagaaatca aaaaatacga atccttgatt gaagaacaaa
    29521 ttccttatgc caactatgaa tctgttagaa atgcagtctt ctccttagag aaaagactgg
    29581 ctgacttagg tgttgacaga aaatcttgtc atatcgattt ggtgcctgaa aactttatcg
    29641 aatcacctca aggacgactt tatttgattg actgggaata ttcatcaatg aatgatccaa
    29701 tgtgggattt ggctgccctc tttttagagt ctgaattcac ttcccaagag gaagaaactt
    29761 tcttatctca ctatgagagt gaccaaacac cggtttctca tgaaaagatt gctatttata
    29821 aaattttaca agatactatt tggagtctat ggactgtcta taaggaagag caaggtgaag
    29881 attttggtga ctatggtgtg aatcgttacc aaagagctgt taaaggtttg gcttcttatg
    29941 gaggttcaga tgaaaagtaa aaacggagtt ccttttggcc ttctctcagg tattttctgg
    30001 ggcttgggtc taacggttag tgcttatatc ttttcgattt ttacagattt gtcacccttt
    30061 gtggtggctg cagctcatga ttttttgagc atctttatct tactagcttt tctcttggta
    30121 aaagaaggga aagttcgcct ctcaattttc ttaaatattc gcaatgtcag tgttatcatc
    30181 ggagccttgc tagcaggccc tatcggtatg caggccaatc tttatgcagt taagtatatc
    30241 ggaagttctt tagcttcatc tgtatcggct atttaccctg cgatttcagt tctattggct
    30301 ttcttctttt tgaagcacaa gatttcgaaa aatactgtat ttgggattgt cttgattatt
    30361 ggagggatta ttgcccagac ctataaagtt gaacaggtta attctttcta cattgggatt
    30421 ctttgtgctt tggtttgtgc tattgcatgg ggaagtgaga gtgttcttag ctcttttgcc
    30481 atggaaagtg aattgagtga aatcgaagcc ctcttaatcc gtcaagtaac ttcgttcttg
    30541 tcctatcttg tgattgtgct cttctctcat cagtcattta ctgcagtagc caatggacaa
    30601 ttgctaggtc tcatgattgt ttttgcagcc tttgatatga tttcctactt ggcttattat
    30661 atcgctatca atcgcttgca accagccaag gctacaggct tgaacgtgag ctatgtagta
    30721 tggacggtct tgtttgcagt tgttttcttg ggtgcaccgc tagatatgct gaccattatg
    30781 acgtcacttg tcgtcattgc tggagtttat attattatta aagaataaag gagattcgtg
    30841 tgaaagccat catcttagca gcgggattgg gaactcgctt gcgtcctatg actgaaaata
    30901 cccctaaagc cttggttcag gttaatcaaa aacctttgat tgagtaccaa attgagtttc
    30961 tcaaagaaaa aggaatcaat gacatcatca tcattgttgg ttatcttaaa gaacaattcg
    31021 attacttgaa agagaaatac ggtgttcgtc tcgttttcaa tgataaatac gctgactaca
    31081 ataactttta ctctctctat cttgtaaaag aagaattagc caatagttat gttatcgatg
    31141 ccgataacta tctctttaaa aatatgttcc gcaatgattt gacacgttct acttatttta
    31201 gtgtctatcg tgaagattgt accaacgaat ggttcttggt ctatggagat gactacaagg
    31261 ttcaaaacat tattgttgat agcaaggcag gtcgcatcct tagtggtgta tccttctggg
    31321 atgctccaac agcagaaaaa attgttagct ttatcgataa ggcttatgca agcggcgaat
    31381 ttgttgatct ctattgggac aatatggtta aggataacat caaagagcta gatgtctatg
    31441 ttgaagaatt agaaggcaat agcatttatg agattgatag tgtccaagac tatcataaat
    31501 tagaagaaat tcttaaaaac gaaaattaaa agcttccaac atctgacaaa atagtcggat
    31561 gtttttttga ttttttacga acttttacga atagatagat gagtagaaaa agaaatggag
    31621 ttatttatga aaatcacaaa ctatgaaatc tataagttaa aaaaatcagg tttgaccaat
    31681 caacagattt tgaaagttct agaatacggt gaaaatgttg atcaggagct tttgttgggt
    31741 gatattgcag atatatcagg ttgccgtaat ccagccgttt ttatggaacg ttattttcag
    31801 atagacgatg cgcatttgtc gaaagagttt caaaaatttc catctttctc tattttagat
    31861 gactgttatc cttgggattt gagtgaaata tatgatgcgc ctgtactttt attttacaag
    31921 ggaaatcttg acctcctgaa attcccgaag gtagcggtcg tgggcagtcg tgcttgtagc
    31981 aaacagggag ctaaatcagt tgaaaaagtc attcaaggct tggaaaatga actggttatt
    32041 gtcagtggtc tggccaaggg cattgacaca gcagctcata tggcagctct tcagaatggc
    32101 ggaaaaacca ttgcagtgat tggaacagga ctggatgtgt tttatcctaa agccaataaa
    32161 cgcttgcaag actacatcgg caatgaccat ctggttctaa gtgaatatgg acctggcgaa
    32221 caacctctga aatttcattt tcctgcccgt aatcgcatca ttgctggact ttgtcgtggt
    32281 gtgattgtag cagaggctaa gatgcgttca ggtagtctca ttacgtgtga gcgagcaatg
    32341 gaagaaggac gcgatgtctt tgctattcct ggtagcattt tagatggact atcagacggt
    32401 tgccatcatt tgattcaaga aggagcaaaa ttggtcacca gtgggcaaga tgttcttgcg
    32461 gaatttgaat tttaaaaatg acctaagcta gaattctaag aaaaaatcaa ttttaagaga
    32521 aaatgaaccc aacatttcca taataaaacg catattagca agtttttaac acttgataat
    32581 atgcgttttt tctaagtgga ttagtagagt agaggatttt tctcatataa tactcttcga
    32641 aaatctcttc aaactacgtc agcttccatc tgcaacctca aaacagtatt ttgagctgac
    32701 ttcgtcagtc ttatctacaa cctcaaagca gtgctttgag caacctgtgg ctagcttcct
    32761 agtttgcgct ttgattttca ttgagtataa gggaaagtat agtgaattga aataagatgt
    32821 gaacaactct atcaggaaag tcaaattaat ttatagaaat attttagcag ccaaggtgca
    32881 ctgttataga ttcaatacac tataatttag tgtaattgag aaaggagaaa tgattgtgat
    32941 tgatgttggc taggttatgt tcaatgattc ctaccgtctc aaatcttgtc agtaaggaaa
    33001 aataaattct tcaaaagtag agattacaag gcttgtttaa gaaagaattc aaagaccttg
    33061 acaaataaaa ataaaatggt tattataaaa aatggtctga aatagatgat gatacttttc
    33121 gaaaatcttt ttacgtcagc tcagctttgc cttgctgtgt tttgagcaag ctacggttag
    33181 cttccgagtt tgattttcat ttactagaaa tgaaactgat gagagatatc agtagacatt
    33241 tgagtcagga tattatggaa aatgataaaa agagctcgtg agattggcat atcagactac
    33301 taaagtattg agtttgttag gattttagcg actagttagc tgggaaagga agatatttgt
    33361 gacaaataat aaactgtatt cgttgataga atttagaaat aaaatatatg aagaattaga
    33421 actttccaga agtgatttag cgattttact atgtgccatg cttatcgcct ctatcggatt
    33481 aaatatggat tcgactcccg tgattattgg agccatgtta atctctcctt tgatgacacc
    33541 tattctggga gtggggctct ctctagctat atttgatttt aaattgttaa gaaaatcttt
    33601 taaaatatta gctattcaaa ttcttgccag tttaatagct tcaacacttt atttttatct
    33661 ttctcccatt tcgtatgcta gttcggaaat tgttgctaga acctctccga ctatttggga
    33721 tgttctcatt gcttttgtag gagggatagc aggtattatt ggtgctagga aaaaagagac
    33781 caataatatt gttcctggtg ttgctattgc aaccgccttg atgcctcctc tttgtacagt
    33841 aggttatgct attgcttctg ctaatctaaa atttatcata ggctcctctt acctattcct
    33901 catcaattgt agctttattg tcattgcgac ttatataggt gttaggttga tgatggttaa
    33961 gaaacattat tttaaagata atgaagaaga ctctaaaatg cgtaggattt tgcttctagt
    34021 tgctgttttg ctgatgattc cgagtttcat ctctgcaacg actttagtga gagaaacgtt
    34081 gaaaaaagag tcccttaaga aatttatatc agagcagttt caggggcata atattttgaa
    34141 aaaaacctat tctaaaaaga ctcataccct aaagctaacc atttcaggaa attatttgac
    34201 agaagaagaa ctcgatatga tttcaagtaa gagaggtgac tatggtttaa gtgatgtttc
    34261 tgttcaagtt tcacaattgt ctgattcaga acaacttagt aaggaagaac tggtggagta
    34321 tttcttccag tatatcaagg ataaggaagc aaaagaaaag gaaaaagcta ataagtttta
    34381 tacagagtct gaggagcaat aatttcttga gaatagctgg tttctctcgt gagtcttcta
    34441 tgtatatcaa aggaagactg aggttttaag tataaaactt ttcttctatt atagtagcta
    34501 agtcttgaca gggttcaaaa aatggtttac actttataaa gtttattact ttgaaaaggt
    34561 gtgatactgt ggctacggca acaaaaaaga aaaaatcaac agttaaaaaa aatctagtca
    34621 tcgtggagtc gcctgctaag gccaagacga ttgaaaaata tctaggcaga aactacaagg
    34681 ttttagccag tgtcgggcat atccgtgatt tgaagaaatc cagtatgtcc gtcgatattg
    34741 aaaataatta tgaaccgcaa tatatcaata tccgaggaaa aggccctctt atcaatgact
    34801 tgaaaaaaga agctaaaaaa gctaataaag tttttctcgc gagtgacccg gaccgtgaag
    34861 gagaagcgat ttcttggcat ttggcccata ttctcaactt ggatgaaaat gatgccaacc
    34921 gtgtggtctt caatgaaatc accaaggatg cagtcaaaaa tgcttttaaa gaacctcgta
    34981 agatcgatat ggacttggtc gatgcccaac aagctcgtcg gatcttggat cgcttggtag
    35041 ggtattcgat ttcgcctatt ttgtggaaga aggtcaagaa gggcttgtca gcaggtcgcg
    35101 ttcagtccat tgcccttaaa ctcatcattg accgtgaaaa tgaaatcaat gccttccagc
    35161 cagaagaata ctggacagtt gatgctgtct ttaaaaaggg aaccaaacaa tttcatgctt
    35221 ccttctatgg agtagatggt aaaaagatga aactgaccag caatgacgaa gtcaaggaag
    35281 tcttgtctcg tctgactagt aaagactttt cagtagatca ggtggataag aaagagcgca
    35341 agcgcaatgc tcctttaccc tataccactt catctatgca gatggatgct gccaataaaa
    35401 tcaatttccg tactcgaaaa accatgatgg ttgcccaaca gctctatgaa ggaattaata
    35461 ttggttctgg tgttcaaggt ttgattacct atatgcgtac cgattcgact cgtatcagtc
    35521 ctgtagcgca aaatgaggcg gcaagcttca ttacggatcg ttttggtagc aagtattcta
    35581 agcacggtag caaggtcaaa aacgcatcag gtgctcagga tgcccatgag gctattcgtc
    35641 cgtcaagtgt ctttaataca ccagaaagca tcgctaagta tctggacaag gatcagctca
    35701 agctatatac ccttatctgg aatcgttttg tggctagcca gatgacagcg gccgtttttg
    35761 ataccatggc tgttaaattg tctcaaaatg gagttcaatt tgctgccaat ggtagtcagg
    35821 ttaagtttga tggttatctt gccatttata atgattctga caagaataag atgttaccgg
    35881 acatggttgt tggagatgtg gtcaaacagg tcaatagcaa accagagcaa catttcaccc
    35941 aaccgcctgc ccgttattct gaagcaacac tgattaaaac cttagaggaa aatggggttg
    36001 gacgtccatc aacctatgcg ccaaccattg aaaccattca gaaacgttat tatgttcgcc
    36061 tggcagccaa acgttttgaa ccgacagagt tgggagaaat tgtcaataag ctcatcgttg
    36121 aatatttccc agatatcgta aacgtgacct tcacagctga aatggaaggt aaactggatg
    36181 atgtcgaagt tggaaaagag cagtggcgac gggtcattga tgctttttac aaaccattct
    36241 ctaaagaagt tgccaaggct gaagaagaaa tggaaaaaat ccagattaag gatgaaccag
    36301 ctggatttga ctgtgaagtg tgtggcagtc caatggtcat taaacttggt cgttttggta
    36361 aattctacgc ttgtagcaat ttcccagatt gccgtcatac ccaagcaatc gtgaaagaga
    36421 ttggtgttga gtgtccaagc tgtcatcagg gacaaattat tgagcgaaaa accaagcgta
    36481 atcgcctatt ctatggttgc aatcgctatc cagaatgtga atttacctct tgggacaagc
    36541 ctgttggtcg tgactgtcca aaatgtggca acttcctcat ggagaaaaaa gtccgtggtg
    36601 gtggcaagca ggttgtttgt agcaaaggcg actacgagga agaaaagatt aaataagagg
    36661 aggggcccga aagtaaattt caggctcctt ttggttagaa cttgacaaaa tacatcattt
    36721 tatgcgaaac tagaagaaga ttattttata ctcaatgaga atcaaagagc aaattagaaa
    36781 gctagtcgca ggttgctcaa agcactactt tgaggttgaa gatggaagct gacctggttt
    36841 gaagagattt tcgaagagta ttaactagga gaagttatgc gtattatcta tctaattatt
    36901 ggttttttat cgctgacctt ggctattgtt ggggttgttt tacccttgtt gcctacaaca
    36961 cctttccttt tgttgtctat tgcttgtttc tccagaagtt ccaagcgatt cgaagattgg
    37021 ctttatcata ccaagctcta tcaagcatat gtagctgatt ttcgtgagac caagtctatt
    37081 gcgcgtgaac gaaagaaaaa aatcatcgtc tctatctacg tcttgatggg aatttctatt
    37141 tattttgcac ctcttttacc agtcaaaatc ggtctgggtg ctttgaccat ctttattact
    37201 tattatctct tcaaggtcat tccagacaaa gaatagttaa aacagtagtt atttgccttg
    37261 ataaaattga aagcatattc ataacaatat gatataataa aattgaagta atattcaagg
    37321 agaatcaaat gatttacgaa ttttgtgctg aaaatgtgac tttacttgaa aaagcgatgc
    37381 aggctggagc tcgtcggatt gaactctgtg ataatctagc agttggtggg acaacaccca
    37441 gctatggagt gactaaggca gcggttgaac tggcagctaa ctacgataca accatcatga
    37501 ccatgattcg gccacgtggt ggtgactttg tctataatga cctagaaatt gctatcatgc
    37561 tagaagacat tcgtttgact gctcaggctg gaagtcaagg ggttgtattt ggagctttaa
    37621 ctgctgataa aaagttggat aagcctaatc tggaaaagtt aattgctgca tcaaaaggaa
    37681 tggaaattgt ctttcacatg gcctttgatg aactaagtga tgaagatcaa ccggaagcta
    37741 ttgactggct cagtcaagcc ggtgtcactc gtatcctaac tcgtgctggt gtgtctggcg
    37801 actccttaga aaaacgtttt gttcactatc acagaatttt ggagtacgct aaaggtaaaa
    37861 ttgaaattct accaggtggg gggattgacc ttgaaaaccg tcaaaccttt atcgaccagg
    37921 tgggggtaac acaattgcat ggtactaagg ttgtttttta aaaaatagaa aggaactgct
    37981 agctttgggt agcagttttc acttatgttt gaaattttta aatcctatca atttaatcaa
    38041 gaaaaggctc atgattatgg ttttatagaa aatagcgaag tctggacata tagttgccag
    38101 attttgcaag gtgactttgt catgactgtg tccatcactg ctgataatgt gaactttcaa
    38161 gtctttgacc aagagactgg tgacctctat cctcacgttt atatggaaag catgagggga
    38221 agttttgtcg gaaatgtccg tgaggcttgt ctggagattc tttaccagat tcggaaggct
    38281 tgttttgatg tgcaagattt tatctgtcat cagactaagc gtatcatgac tcaagttcag
    38341 gaaaagtatg gaaaccagtt ggagtatctg tgggaaaaat cgcctgatac agctgtattg
    38401 cgccatgaag gcaatcaaaa gtggtatgcc gtcttgatga aaatctcttg gaataagctg
    38461 gaaaagggca gagaaggaca agtggaagca gtcaacctca agcatgacca agtagctaat
    38521 ttgctttcac aaaaggggat ttatccagcc ttccatatga gcaagcgcta ctggattagt
    38581 gtgtcccttg atgatacttt atcagatgaa gaagtactgg aattgataga aaaaagttgg
    38641 aacttaacct ctaaaaaatg aaatatttta ataattttca tgaactttca attagctaaa
    38701 tattctttac tgaagagatt tttagaaaat ataggattta ccacactaga ggaatatggt
    38761 gccatcttca aatacctgat tgagaatgtc aagacggatc gtcagatcat ctattcgcct
    38821 cactgtcatg atgacctcgg aatggcagtg gcaaatagcc ttgctgctgt caagaatggt
    38881 gcaggacgtg ttgaagggac tatcaatggt attagggagc gagctgaaaa tgctgctttg
    38941 gaagaaattg cagtggctct caatattcgc caagattact accaagtaga aaccagtatt
    39001 gtcctaaatg agaccatcaa tacgtcagaa atggtttctc gcttctctgg tattccagtt
    39061 cctaaaaaca aagccgtcgt tggtggcaat accttctccc acgaatctgg tattcaccaa
    39121 gatggagtcc ttaaaaatcc tctcacttat gagatcatca cacctgaatt ggttggtgtt
    39181 aagattctgc ttggaaaatt atctggtcgc catgcttttg ttgagaaact gagagaattg
    39241 gccctagatt ttacagaaga ggatatcaaa ccactctttg ctaagttcaa ggcactggtc
    39301 gataagaagc aagaaatcac agatgcagat attcgagctt tggtagctgg aaccatggtt
    39361 gaaaatccag aaggcttcca ctttgatgat ttacaacttc aaactcatgc agataatgac
    39421 attgaagcgc tcgttagcct agccaatatg gatggtgaga aagtcgaatt taatgcgaca
    39481 gggcaaggtt ccgttgaagc aatctttaat gctatcgata agttctttaa ccaatctgtt
    39541 cgtttggtgt cctacactat cgatgcggta acagatggaa tcgataccca ggatcgggtt
    39601 ttggtcactg ttgaaaacag agatacagaa accatcttta atgcagcagg gcttgatttt
    39661 gatgtgttga aggcttctgc tattgtctat ataaacgcta atacctttgt tcaaaaagag
    39721 aatgcaggtg agatgggacg cagtgtttct taccacgata tgcctagtgt gtaaaggaga
    39781 aggctatggc aaagaaaata gtagctctag caggagacgg aattggccca gaaatcatgg
    39841 aggttggttt agaagttctg gaggctctag ctgaaaaaac aggttttgac tatgagattg
    39901 acagacgacc gttcggaggt gcagatattg atgcagcatg acctccctta cctgatgaaa
    39961 cccttaaggc aagtagggaa gcagatgcta tcctactagt agctatcggt agtcctcagt
    40021 atgatggagc agtggttcgc cctgaacaag gcctgatggc tctccgtaag gaactcaatc
    40081 tttacgctaa tattcgtcct gtaaaaatct ttgacagtct caagcatttg tcactactca
    40141 aactggaacg aattgctggt gtagactttg tcgtggtgcg tgaattgaca ggcgggattt
    40201 actttggaga tcatattctt gaagagcgca atgcgcgtga tatcaacgac tatagctatg
    40261 aggaagtgga gcggattatt cgcaaagcct ttgaaattgc aagaaatcgc agaaaaatcg
    40321 ttactagtat cgataagcaa aatgttctag cgacctcaaa actctggcgg aaagtagctg
    40381 aggaagtcgc acaggatttc ccagatgtaa ccttggaaca tcagctggta gactcagctg
    40441 ctatgcttat gattaccaat cctgctaagt ttgatgttat tgtaacggag aatctttttg
    40501 gagatatttt atctgatgaa tcaagcgtct tatctggtac acttggggtt atgccatcag
    40561 ccagtcattc tgaaaatgga ccaagtctct atgaacctat tcacagttca gcacctgata
    40621 ttgcaggtca aggaattgcc aatcctattt ccatgatttt atcagtttcc atgatgttga
    40681 gagatagttt cggacgttat gaggatgcag agcgtatcaa acgtgctgtt gagacaagtc
    40741 tggcggcagg aattttaacg agagatatag gaggtcaggc ttcaacaaag gaaatgacgg
    40801 aagctattat tgcaaggtta tgaagttaga cgaaaaaatt actctagtcc ttttgatttg
    40861 gaatgtcatc attttcttga tttatggtat tgacaaatct aaggcaagga gaagagtttg
    40921 gcgcatccct gagaaaatct tacttatttt agcctttact tttggtggtt ttggtgcctg
    40981 gctagcagga atcatctttc accacaagac tcgaaaatgg tactttaaaa tagtttggtt
    41041 tcttgggatg gtgaccacac tagtagcctt atattttatt tggaggtaat ggatggcagg
    41101 gtcttcgagg gaatacgctg cttgggctct agcggactat ggttttaagg tcgtgattgc
    41161 aggatctttc ggtgacattc attacaataa tgaactcaat aatggcatgt tgccaatcgt
    41221 tcagcctaga gaggttagag agaaactagc ccagctaaaa ccaaccgacc aggtaactgt
    41281 ggacttggaa caacaaaaaa tcatctcacc agttgaagaa ttcaccttcg agatagatag
    41341 cgagtggaaa cataaactcc taaatagttt ggatgatatc ggtattacct tgcagtatga
    41401 agagttgatt gctgcttatg aaaaacaacg accagcctac tggcaggatt agaaaaaata
    41461 gaaaaggaga tatagtaaac tgaaataaga tgtaaacaaa tgaattggag cttaacatcc
    41521 atttccagca attttttaga aactacagtg gactattctg gattcaacac attataaaat
    41581 tatgacaaaa cacattcaca agaaggctac gacattttaa aaggtgaggg cggatgtatc
    41641 gtttgcccta ctaaagttgg ttacattatc atgaccagtg acaaggcagg acttgagcgt
    41701 aagttcgcag ccaaagaacg taagcgtaac aaaccaggtg ttgttctctg cggtagcatg
    41761 gatgaacttt gcgctttagc gcaactcaac ccagaaattg aagcattcta ctaaaaacat
    41821 tgggatgaag atattcttct tggttgtatc cttccttgga aaccagaagc ctttgaaaaa
    41881 ctcaaagcat acggggatgg ccgtgaagaa cttatgactg atgtacgtgg tactagctgt
    41941 tttgttatca agtttggaaa agcaggtgaa caattggctg ccaagctttg ggaagaaggt
    42001 aaaatggtct acgcctcatc tgcttcaatg acaaaacgat tgaaactcgc tatgagcaag
    42061 gtgtaatggt gtctatggtc gataaggacg gcaaactcat cccagaacaa ggaggagcac
    42121 gttcaacttc accagctcca gttgtgatcc gtaaagggct tgacattgat atagtaaaat
    42181 gaagtaagag caggacaaat taatcaggac agtcaaatcg atttctaaca atgttttaga
    42241 agtagaggtg tactattcta gtttcaatcc actataaaat catgatgcac ctgtcagata
    42301 cttttaactc atgggactac cgtcaggttg agtattatta ggatagagaa gaagtctagt
    42361 gttaaggaca ttacagctca taatactagg cttttttata gaaattcttt tctttttcta
    42421 taggatatgg tattctatgt agaaaatata tgttaataag taatgccaat atttaaacat
    42481 cattagtaaa aggagttaga ttgatgaata aaagaaaagt tagtttagaa gatttttata
    42541 aatggtatag tctaaataaa gaagagttat taaataaggc aactgttggt gaaaagttta
    42601 atgataaatt aaaagaagag tttctccagg aatggccttt ggataggatt ttaacaatgt
    42661 caatcgatga atatgtaata ggaaagggac agcaaaataa gtctttatgc tacgctcttg
    42721 agaagggaaa atacaaaaat ctatttcttg gaatttctgg tggctcagct tcaaaatttg
    42781 gtatttattg gaataaaaaa acaaacaaat ataaagatca agctaataat gagatttcag
    42841 agttggatca gcgattttca aaattaaaat cagatttgta tgaaattatc aaagaaggta
    42901 ttcgttttaa ctttgaaaat cctatttttg atatgaaaag atcaacaaat gaatttattg
    42961 gtcgttctgc tatggtgaca aaattacttt gtatctatac tgagggagat cctttctttg
    43021 gtgtaaatat taatagtcag aaagaatttt ggaaccactt tgtttctcag acaaatcaag
    43081 gtggacctta tctgcaaaat cataaaataa ttgaactgat gtccaaaact tatcctgagt
    43141 tggagccatc gaaattagga actatgcttt ttgagtattc taagcttttt atggaaaata
    43201 aggaagacaa tagtacaatg gattcatcaa acaattttcg tcatcaatta actcaatctc
    43261 tattaaagtc tccaaacctt atccttcgtg gtgctcctgg cacaggaaag acttatcttg
    43321 ctaaagaaat tgccaaagaa ttaacggatg gcaacgaaga tcaaatcgga tttgtacaat
    43381 ttcacccatc atatgattat acggattttg tagaaggttt aagaccagta tcaaatgggg
    43441 atggagctat tgagtttagg ctacaggacg gtatttttaa agatttttgt cagaaagcaa
    43501 aagaaaccca attgattgga ggacaagata attttgatga ggcttgggat tcttacttag
    43561 aatatataaa tgttgctgaa gaaaaagaat atataacaaa aacatcttac ttatctgtta
    43621 atagtagaca aaatttgtca gtaaattatg atagtggtgt tccaggatgg tcactaccta
    43681 g
//
LOCUS       DAVBCA010000011        41426 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.011, whole genome shotgun sequence.
ACCESSION   DAVBCA010000011 DAVBCA010000000
VERSION     DAVBCA010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 41426)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41426)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41426
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.011"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(98..739)
                     /gene="plsY"
                     /locus_tag="VQU19_000547"
     CDS             complement(98..739)
                     /gene="plsY"
                     /locus_tag="VQU19_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HET2479845.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            875..2818
                     /gene="parE"
                     /locus_tag="VQU19_000548"
     CDS             875..2818
                     /gene="parE"
                     /locus_tag="VQU19_000548"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HET2479846.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVINTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            3238..5709
                     /gene="parC"
                     /locus_tag="VQU19_000549"
     CDS             3238..5709
                     /gene="parC"
                     /locus_tag="VQU19_000549"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HET2479847.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKNTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAVTRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            5841..6863
                     /locus_tag="VQU19_000550"
     CDS             5841..6863
                     /locus_tag="VQU19_000550"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HET2479848.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGTGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            6919..7623
                     /locus_tag="VQU19_000551"
     CDS             6919..7623
                     /locus_tag="VQU19_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2479849.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     SRTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSDM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGFPVVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKYIK"
     gene            7688..8377
                     /locus_tag="VQU19_000552"
     CDS             7688..8377
                     /locus_tag="VQU19_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HET2479850.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            8374..9297
                     /locus_tag="VQU19_000553"
     CDS             8374..9297
                     /locus_tag="VQU19_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HET2479851.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            9312..9956
                     /gene="pcp"
                     /locus_tag="VQU19_000554"
     CDS             9312..9956
                     /gene="pcp"
                     /locus_tag="VQU19_000554"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HET2479852.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            10124..10354
                     /locus_tag="VQU19_000555"
     CDS             10124..10354
                     /locus_tag="VQU19_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HET2479853.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            10404..10484
                     /locus_tag="VQU19_000556"
     tRNA            10404..10484
                     /locus_tag="VQU19_000556"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10438..10440,aa:Tyr,seq:gta)
     gene            10494..10565
                     /locus_tag="VQU19_000557"
     tRNA            10494..10565
                     /locus_tag="VQU19_000557"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10526..10528,aa:Gln,seq:ttg)
     gene            10727..11929
                     /gene="rpsA"
                     /locus_tag="VQU19_000558"
     CDS             10727..11929
                     /gene="rpsA"
                     /locus_tag="VQU19_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HET2479854.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            12015..12512
                     /locus_tag="VQU19_000559"
     CDS             12015..12512
                     /locus_tag="VQU19_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HET2479855.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTTWDFTM
                     FEEKS"
     gene            12512..14167
                     /gene="dnaX"
                     /locus_tag="VQU19_000560"
     CDS             12512..14167
                     /gene="dnaX"
                     /locus_tag="VQU19_000560"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HET2479856.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVSLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNVGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            14195..14389
                     /locus_tag="VQU19_000561"
     CDS             14195..14389
                     /locus_tag="VQU19_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HET2479857.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            14539..15309
                     /gene="sufC"
                     /locus_tag="VQU19_000562"
     CDS             14539..15309
                     /gene="sufC"
                     /locus_tag="VQU19_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HET2479858.1"
                     /translation="MSVLEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITRLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            15337..16599
                     /gene="sufD"
                     /locus_tag="VQU19_000563"
     CDS             15337..16599
                     /gene="sufD"
                     /locus_tag="VQU19_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HET2479859.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKINYLERLESRGEGSAKATANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSYADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            16610..17836
                     /locus_tag="VQU19_000564"
     CDS             16610..17836
                     /locus_tag="VQU19_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET2479860.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILTEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQSASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPASARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            17823..18263
                     /locus_tag="VQU19_000565"
     CDS             17823..18263
                     /locus_tag="VQU19_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HET2479861.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQDQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            18313..19725
                     /gene="sufB"
                     /locus_tag="VQU19_000566"
     CDS             18313..19725
                     /gene="sufB"
                     /locus_tag="VQU19_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HET2479862.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(19956..21197)
                     /locus_tag="VQU19_000567"
     CDS             complement(19956..21197)
                     /locus_tag="VQU19_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HET2479863.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITAYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFIDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            21300..22409
                     /locus_tag="VQU19_000568"
     CDS             21300..22409
                     /locus_tag="VQU19_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HET2479864.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            22943..23290
                     /gene="ssrA"
                     /locus_tag="VQU19_000569"
     tmRNA           22943..23290
                     /gene="ssrA"
                     /locus_tag="VQU19_000569"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(23473..23560)
                     /locus_tag="VQU19_000570"
     tRNA            complement(23473..23560)
                     /locus_tag="VQU19_000570"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(23524..23526),aa:Ser,seq:gga)
     gene            23722..24462
                     /locus_tag="VQU19_000571"
     CDS             23722..24462
                     /locus_tag="VQU19_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET2479865.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNITVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            24459..25370
                     /gene="pfkB"
                     /locus_tag="VQU19_000572"
     CDS             24459..25370
                     /gene="pfkB"
                     /locus_tag="VQU19_000572"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HET2479866.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVESVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDVVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            25367..27319
                     /locus_tag="VQU19_000573"
     CDS             25367..27319
                     /locus_tag="VQU19_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET2479867.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTDHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGALYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            27483..29708
                     /locus_tag="VQU19_000574"
     CDS             27483..29708
                     /locus_tag="VQU19_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HET2479868.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKTQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEIAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(29753..30181)
                     /locus_tag="VQU19_000575"
     CDS             complement(29753..30181)
                     /locus_tag="VQU19_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2479869.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTVATIASILGLITASITIMN
                     ALDNNKNIKKEPTTSQTTTIVKEIQKESPKENTSPTKETNTSQEKTQQEETPKSSVKE
                     EKKEDQKTATQDSSTPASSKPATENEKQSNAPTSENKSNQ"
     gene            30319..31461
                     /locus_tag="VQU19_000576"
     CDS             30319..31461
                     /locus_tag="VQU19_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET2479870.1"
                     /translation="MIYFDNSATTKPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWLIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKSQGFEVDFAPVDKKGLVDVEALAGLIRHDTILVSIMAVNNEIGSIQPIEAI
                     SEFLADKPTISFHVDAVQALAKIPTEKYLTERVDCATFSSHKFHGVRGVGFVYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     NYPDIFVFSDEENFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAKSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            31470..32684
                     /gene="thiI"
                     /locus_tag="VQU19_000577"
     CDS             31470..32684
                     /gene="thiI"
                     /locus_tag="VQU19_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HET2479871.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYTQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSSVQEIMRDIYKE
                     GMTFKISSKRSDHNFELDSRELNQTLGGAVFEAIPNVQVQMKSPDINLQVEIREEAAY
                     LSYETIRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            32819..33643
                     /locus_tag="VQU19_000578"
     CDS             32819..33643
                     /locus_tag="VQU19_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET2479872.1"
                     /translation="MNQSYFYLKMKEHKLKVPYTGKERRVRILLPKDYEKDTDRSYPV
                     VYFHDGQNVFNSKESFIGHSWKIIPAIKRNPDISRMIVVAIDNDGMGRMNEYAAWKFQ
                     ESPIPGQQFGGKGVEYAEFVMEVVKPFIDETYRTKADCQHTAMIGSSLGGNITQFIGL
                     EYQDQIGCLGVFSSANWLHQEAFNRYFECQKLSPDQRIFIYVGTEEADDTDKTLMDGN
                     IKQAYIDSSLCYYHDLIAGGVHLDNLVLKVQSGAIHSEIPWSENLPDCLRFFAEKW"
     gene            33665..34404
                     /locus_tag="VQU19_000579"
                     /pseudo
     CDS             33665..34404
                     /locus_tag="VQU19_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546805.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
     gene            34417..35583
                     /locus_tag="VQU19_000580"
     CDS             34417..35583
                     /locus_tag="VQU19_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HET2479873.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIGRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMEQMIADFGQRQE"
     gene            36091..37584
                     /locus_tag="VQU19_000581"
     CDS             36091..37584
                     /locus_tag="VQU19_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HET2479874.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            37597..38643
                     /locus_tag="VQU19_000582"
     CDS             37597..38643
                     /locus_tag="VQU19_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET2479875.1"
                     /translation="MKKVKLGEVLSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQYLREHSTGATIPHLNKNILLDLQLELLGIEEQENIICILNTIKRLITKRK
                     LQLDELNLLVKSRFNEMFGDVILNEKEWKVSKWNEILTIRNGKNQKQVEDADGKFPIY
                     GSGGIMGYAKDWIVKKNSVIIGRKGNINKPILVRENFWNVDTAFGLEPVLEKINSEYL
                     FYFCQLYNFEKLNKAVTIPSLTKSDLLNISIPLPPLALQNEFADFVALVDKSQFACEI
                     AIKVWRNSLKFSII"
     gene            38673..41369
                     /locus_tag="VQU19_000583"
                     /pseudo
     CDS             38673..41369
                     /locus_tag="VQU19_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
BASE COUNT        12552 a         7447 c         9187 g        12240 t
ORIGIN      
        1 taaaactaaa aggacttagc cctgtgcaat acagaactaa atccttcgga taaattaatt
       61 gtctaacttt tggggtgcag ttcacagaac tggcatttta ttttttagga tcttgatggg
      121 ttaggttcaa tccccaaggg accaaatttt cagttttatt tttgatacga gctatattgt
      181 ccttatgacg aatgataatc aaactagcaa gtgctaagat aatagcgatg aagagagagt
      241 catagttact caggataaaa ccaaaaagtg gaaagagcag aaccccgata acagccgcga
      301 tcgatgctgt gacactagac agtgaaatca tactgccaag atagagagct ccaaagaaga
      361 taatcgcaag gtagagacag aagataggcg caaatccgaa aattactcca gcactggttg
      421 cgacagcctt accaccttta aatcctgcaa agatagggaa ggtatggccg ataacagcca
      481 aaagtccaaa gatgagagga gaaacgcctt gtagatgaaa aataatcgga agcagcgttg
      541 ctagggttcc tttgaaaaag tcaatcacaa aggttgccat accagctttc ttacctaaaa
      601 tgcggaaggt attggtcgtt ccagtgttac cagaaccatg ctcgcgtaga ttgatttgaa
      661 agaatacttg tccaatccag agaccagatg gaatcgaacc cagcagatag gctaggatta
      721 ataaaactat tgtaatcata ctcctattat atcatgaatt gggaaagaaa agcagagaat
      781 ctctgctaaa attgtcacat cggagaaaga aaaattttgc aaaatccttg gaaaacctgt
      841 agaatagtaa agatgaacga ataggaggtt ccttgtgtca aaaaaggaaa tcaatattaa
      901 caattataat gatgatgcta ttcaggtgct agaagggttg gatgcggtcc gaaaacgtcc
      961 agggatgtat attggatcga ccgatggcgc tggtcttcat cacctagttt gggaaatcgt
     1021 tgataatgca gtcgatgaag ccttgtctgg gtttggtgat cgtatcgatg taaccatcaa
     1081 taaagacggt agtctaacgg ttcaagacca tggacgtggg atgccgacag gtatgcacgc
     1141 tatgggaatt ccaactgttg aggttatctt taccattctt catgccggag ggaaattcgg
     1201 tcaaggtggc tataagacat caggtggact tcacggagtg ggttcttccg ttgttaacgc
     1261 cctttctagc tggttagaag ttgaaattac ccgtgatggc gcagtttaca agcaacgttt
     1321 cgaaaatggt ggaaaacctg tcacgacttt gaagaaaatc ggtacagcac ccaagtctaa
     1381 aacaggcacc aaagttactt ttatgcctga cgcgactata ttttctacga cagatttcaa
     1441 gtacaatacc atttcagagc gccttaatga atcagccttt ctcttgaaaa atgtgacctt
     1501 gtctttaacg gacaagcgaa cagatgaagc gattgagttc cactatgaga atggagtaca
     1561 agattttgtt tcttatctca acgaagataa ggaaatcttg acgccagttc tttactttga
     1621 aggggaagac aatggttttc aagtggaagt agccctccag tacaatgacg gattctcaga
     1681 taacattcta tcctttgtca ataacgttcg caccaaggac ggtggaacgc acgagacagg
     1741 actcaagtct gccattacca aggtcatgaa tgactatgca cgtaaaacag gtcttctcaa
     1801 ggaaaaagat aaaaaccttg aaggttcaga ctatcgtgag ggactagcgg ccgttctttc
     1861 tatcttagtt cctgaagaac acttgcagtt tgaaggacag accaaggata aactaggaag
     1921 ccccctagct cgcccagttg tggatggaat agtggctgat aagttgacct ttttccttat
     1981 ggaaaatggg gaattagctt ctaacctcat ccgcaaggct atcaaggccc gtgatgctcg
     2041 tgaagcagca cgtaaggcgc gtgatgagag ccgaaatggg aagaaaaaca agaaagataa
     2101 gggcttgttg tctgggaaat tgaccccagc ccaatctaag aatcctgcta agaatgaact
     2161 ctatctagtt gagggggact ctgccggtgg ttctgccaaa caaggtcgtg accgcaagtt
     2221 ccaggctatt ctacctcttc gtggtaaggt tatcaataca gccaaggcca agatggcgga
     2281 tatcctcaaa aatgaagaga tcaataccat gatttatacc attggtgcgg gtgttggagc
     2341 agacttctct attgaagatg ccaactatga taagatcatt atcatgaccg atgcggatac
     2401 cgacggtgcc catatccaga ccttgctctt gacatttttc taccgttaca tgcgtccgct
     2461 agtcgaggca ggtcatgtct atattgccct cccacctctt tacaagatgt ccaaaggtaa
     2521 aggaaagaaa gaagaagtgg cctacgcttg gacggacgga gaactagaag aactccgtaa
     2581 acagttcggt aaaggcgcta ccctccaacg atacaaagga cttggtgaga tgaatgcgga
     2641 ccagctctgg gaaacaacca tgaacccaga aacacgtacc ctcatccgtg tcacaattga
     2701 agatttagcg cgcgccgaac gccgcgtcaa tgttctcatg ggagataagg tagaaccacg
     2761 ccgtaaatgg attgaagata atgtcaagtt tacgctagaa gaagcgacag tgttttaatg
     2821 aaagaaaata atatgttagt aaactggaaa ttagagtcgg atgtgaatga ctatgtgaaa
     2881 aagcagtttg aaaatcttgg tttgaaaaaa ttgcaggatt attaatgaag aatctgctat
     2941 gagtgcttat ctcaaagagg cgcttaaggg agcggctaag acacaaacta agactaattt
     3001 tggaaaacca gattttcata ttgaaaaata caaacaggat agtttggtta cttatcgtaa
     3061 ctgaacacgg gaggaattcc cgtaaaatat cttttactgc ataaaaacct actctacatt
     3121 ctttgaaagg agttgaacac gccctagata ctgtgtgaaa aagataaatt ctcttgtgag
     3181 tttgcttact tcaagaattt tctattttca cttggtattt tatgggcttt gtatcttatg
     3241 tctaacattc aaaacatgtc cctggaggac atcatgggag agcgctttgg tcgctactcc
     3301 aagtacatta ttcaagaccg ggctttgcca gatattcgtg atgggttgaa gccggttcag
     3361 cgccgtattc tttattctat gaataaggat agcaatactt ttgacaagag ctaccgtaag
     3421 tcggccaagt cagtcgggaa catcatgggg aatttccacc cacacgggga ttcttctatc
     3481 tatgatgcca tggttcgtat gtcacagaac tggaaaaatc gtgagattct agttgaaatg
     3541 cacggtaata acggttctat ggacggagat cctcctgcgg ctatgcgtta tactgaggca
     3601 cgtttgtctg aaattgcagg ttaccttctt caggatatcg agaaaaatac agttcctttt
     3661 gcatggaact ttgacgatac ggagaaagaa ccaacggtct tgccagcagc ctttccaaac
     3721 ctcttggtca atggttcgac tgggatttcg gctggttatg ccacagacat tcctccccat
     3781 aatttagctg aggtcataga tgctgcagtt tacatgattg accacccaac tgcaaagatt
     3841 gataaactca tggaattctt gcctggacca gacttcccta caggggctat tattcagggt
     3901 cgtgatgaaa tcaagaaagc ttatgagact gggaaagggc gcgtggttgt tcgttccaag
     3961 actgaaattg aaaagctaaa aggtggtaag gaacaaatcg ttattactga gattccttat
     4021 gaaatcaata aggccaatct agtcaagaaa atcgatgatg ttcgtgttaa taacaaggta
     4081 gctgggattg ctgaggttcg tgatgagtct gaccgtgatg gtcttcgtat cgctatcgaa
     4141 cttaagaaag acgctaatac tgagcttgtt ctcaactact tatttaagta caccgaccta
     4201 caaatcaact acaactttaa tatggtggcg attgacaatt tcacacctcg tcaggttggg
     4261 attgttccaa tcctgtctag ctacatcgct caccgtcgag aagtgatttt ggcgcgttca
     4321 cgctttgaca aagaaaaggc tgagaaacgt ctccatatcg tcgaaggttt gattcgtgtg
     4381 atttcgattt tggatgaagt cattgctctt atccgtgctt ctgagaataa ggcggacgcc
     4441 aaggaaaacc tcaaagttag ctatgatttt acggaagaac aggctgaggc tatcgtaact
     4501 ttgcaactgt accgtttgac caataccgat gtggttgtct tgcaggaaga agaagcagag
     4561 cttcgtgaga agattgctat gctggcggct attatcggtg atgaaaggac tatgtacaat
     4621 ctcatgaaga aagaacttcg tgaggtcaag aagaaatttg caactcctcg tttgagttct
     4681 ttagaagaca ctgcgaaagc aattgagatt gatacagcta gtcttatcgc tgaggaagat
     4741 acctacgtca gcgtgaccaa ggcaggttac atcaagcgta ccagtccacg ttcctttgcg
     4801 gcttccacct tggaagaaat tggcaagcgt gatgatgacc gtttgatttt tgttcaatct
     4861 gccaagacaa cccagcacct cttgatgttc acaagtcttg gaaatgtcat ctacagacca
     4921 atccatgagt tggcagatat tcgttggaag gacatcggag agcatctgag ccaaaccatc
     4981 acaaactttg aaacgaatga agaaatcctt tatgtggaag tactggatca gtttgacgat
     5041 gcgacaacct actttgcagt gactcgcctt ggtcaaatca aacgggtaga gcgaaaagaa
     5101 ttcactccat ggcggaccta tagatctaag tctgtcaagt atgctaagct caaagacgat
     5161 acagatcaga ttgtagcagt ggctccgatt aaactagatg atgttgtctt ggttagtcaa
     5221 aatggttatg ccctgcgttt caatatcgaa gaggttccgg ttgtcggtgc taaggcagca
     5281 ggtgtcaagg ctatgaattt gaaagaagat gatgtcctcc aatctggctt tatctgtaat
     5341 acttcgtcct tctacctctt gacccagcgt ggaagcttga aacgtgtttc tattgaggaa
     5401 attctagcaa ccagccgtgc caaacgagga ttacaagtct tgcgtgagtt gaaaaacaaa
     5461 ccgcatcgtg tcttcttggc aggagcagtt gcagagcaag gatttgttgg cgatttcttc
     5521 agtacggaag tggatgtgaa cgaccaaact ctgcttgtcc aatccaataa aggaacaatc
     5581 tatgaaagcc gattgcaaga cttgaacttg tcagaacgca ctagcaatgg aagcttcatt
     5641 tctgacacga tttcagatga agaagttttt gacgcttatc ttcaggaagt agttactgaa
     5701 gataaataag tgaaatgaag aatcagttct aagagctggt ttttattgga gaaattttct
     5761 gaaaattaca aaatatactt gctattttag aaaaatagtg tagaatataa gaaataggtt
     5821 tttagaataa ggagtggaat atgacagtaa cgattgattg ggaaaacctc ggtttttcct
     5881 atatgaaatt accttatcgc tatcttgctc atttcaaaaa tggacaatgg gatcaaggag
     5941 agcttacaga ggatgcaact ttgcatattt cagagtcttc tccaagtctt cactatggac
     6001 aacaagcatt tgaaggtttg aaagcttatc gtactaagga tggcagtgtt caactgttcc
     6061 gtcctgatga aaatgctaaa cgtctgcaac gtacatgtga ccgtctcttg atgccacaag
     6121 ttccgacaga catgtttgta gaagcttgta aagcagttgt ccgtgcgaat gaagaatacg
     6181 taccaccata cggaacaggt ggaaccttat atcttcgccc tcttttgatt ggtgtcggag
     6241 atattatcgg ggtaaaaccg gcagaagagt acattttcac catctttgct atgccagttg
     6301 gaaattactt taaaggtggt ttggtcccaa ccaacttctt gattcaggat gagtacgacc
     6361 gtgcagcacc aaatggtaca ggtgcggcta aggttggtgg aaactatgct gcaagtctct
     6421 taccaggaaa aatggccaag tcacgtcatt tctcagatgt tatctatctg gacccatcaa
     6481 ctcatacaaa gattgaagaa gtcggatcag ctaacttctt tggaattaca gctgataatg
     6541 aatttgtaac accattgagt ccatctatct tgccatctat taccaagtat tccttgcttt
     6601 atttggcaga acatcgcttg ggattaactc ctattgaggg tgatgttcca attgataatc
     6661 ttgaccgttt tgtagaggca ggtgcctgtg gtacagcagc ggttatttct ccaattggag
     6721 gtattcaaca tggtgatgat ttccatgtat tctatagtga aacagaagta ggtcctgtga
     6781 cgcgtaaatt atataatgaa ttgacgggta ttcagtttgg cgatattgaa gcgccagaag
     6841 gttggattgt aaaagtagat taaaataaac caaaggagat tttttatgaa atagaaaaag
     6901 tggctcttaa cagcaggagt ggtcctgagc acgtcagcta ttttagtggc ttgtggaaaa
     6961 actgataaag aagcagatgc accgacaaca ttttcttatg tctatgcagt agatccagca
     7021 tcattgggct acagtatagc gactcgaaca tcgaggacag acgttattgg aaatgttatt
     7081 gatggtttga tggaaaatga taaatacggc aatgttgctc cttctcaaaa agactatgat
     7141 ttgaacagta caggatgggc tccaagctat caagatccag cgtcttactt gaatattatg
     7201 gatccaaaat ctggttctga catgaaacac cttggcatta cgaaaggaaa agataaggat
     7261 gttgtagcta aacctggttt ggataaatat aagaaattgt tagaagatgc tgtttctgag
     7321 accactgacc tagagaagag atatgaaaaa tatgccaaag ctcaagcttg gtcgacagat
     7381 agttcattat tgatgccaac agcttcatct ggtggttttc cagttgtaag taacgtagta
     7441 ccattctcaa aaccatactc acaagttggt attaaggggg aaccatatat ctttaaagga
     7501 atgaaattgc aaaaagatat tgttacaaca aaagaatata acgaggtttt taaaaaatgg
     7561 caaaaagaaa aattggaatc caatagcaaa taccaaaaag aactagaaaa atacattaaa
     7621 taaggaatgg tattgatctt gataaaattt ttaaaatact gtcattttga atataaagga
     7681 gtttgatatg gagtggatta gattaatagg aatagcaatc attgttgtgg gttttatttt
     7741 aaaatttgat acaattgcaa cagtagtctt agctggtttg gttacagctt tagtttcagg
     7801 tgtttctctc gttgaatttt tggagatttt gggaaaagaa tttagcaatc agcgagtgct
     7861 cacgattttt atggttacct tgcctcttgt ggggctgtca gaaacctttg gactcaagca
     7921 acgatcaatc gatttgattc gaaagattaa aggtctgaca gttggaaact tctatacagt
     7981 ttatttcttt attcgagagt tagctggttt cttttcaatt cgtctaggag gacaccctca
     8041 gtttgtcaga cctttggttc aacctatggg agaagcagct gcagagtctc aattaggtag
     8101 aaagttaaca gaggttgaag atgagacaat aaaagcgcgt gcggctgcga atgaaaattt
     8161 tggaaatttc tttgctcaaa atacgtttgt aggtgctggg ggagtcctct tgataggggg
     8221 aacattagat cagttaggct atgaaagcaa ttatgcaggg attgcttcta catctattat
     8281 tgttgctgtt ataacactta ttgtagtggg gatttacaat tatttatttg ataaaaaatt
     8341 gatatcaaaa aagactaggg gaggagaaca aaaatgacag agttggcaaa gcaactatta
     8401 gagttgacct atattgtgat tggttgtcaa tttctccata cagcctattg tagttataaa
     8461 gataaaacaa acccagttcg acttgggaca tctgcatttt ggactctatt gtctattacg
     8521 tttataggtg gttcctatat gccaaatatg agtattggta ttattgtaat cctattatcg
     8581 ctgttaacat tgtttaagca agtccgtatc ggaaccttgc catccttaga tgaaatgaaa
     8641 gccaatattg aatctaacag gttgaaaaat aaaattttta ttccagttat gctgatggca
     8701 atacttgcgt tggtcttagc gcaaatgatt ccagaattta gcaagatttc gattagcctt
     8761 gccgccttgt ttgctacaat ttctgttctt gtgattacca atagtcaccc taagagtctg
     8821 ttatcagaaa ataatcgaat gactcagcaa gtttcaacaa gtgggattgt tcctcaatta
     8881 ttaggggctt tgggggctat ttttactgta gcaggtgttg gtgatgttat ctctcatctg
     8941 attagcggta ttgttccttc agatagtcgc tttataggag ttttggctta tgttcttgga
     9001 atggttctat tcacaatgat tatgggaaat gcttttgcag cattcaccgt tattacagca
     9061 ggtgttggag ttccctttgt atttgctctg ggagctaatc caattgtggc tggtgctctt
     9121 gccatgacag caggttattg tgggacctta ttgaccccaa tggctgctaa ttttaacgct
     9181 ctaccagcag cattgatgga tatgaaagat cagaatggcg ttataaaggc tcaagcaggt
     9241 gttgctctag taatgattgt tattcacata ttcttaatgt actttctcgc attttagtaa
     9301 aggaaaataa aatgaaaata ttggttacag gttttaatcc ttttggaggt gaaaagatta
     9361 atccagcttt ggaggctgta aaattattac catctgagat taatggggct gaagttcgct
     9421 gggtagaaat tccaacggtt ttttataagt cgtcagaagt tttagaggca gaaatattac
     9481 gatatcaacc agatgctgta ctttgtattg gacaagcagg cggcaggacc ggcttaacac
     9541 ctgaacgagt ggctattaat caagatgatg ctcgcatacc tgataacgaa ggcaatcaac
     9601 caattgatac accgattcgt attgatggag catcggccta ttttagtagt ttacctatca
     9661 aagcgatggt acaagctatc aaaaaacagg gacttccggc agttgtatcc aatagtgcag
     9721 gaacctttgt ttgcaatcat ttgatgtacc aagctcttta tttagtggat aaaaaattcc
     9781 ctaatatgag agcaggtttc atgcatattc catatatgat ggaacaagta gtaaataagc
     9841 cgaatactgc aggaatgagt ctatgtgata ttgtaagagg catagaggta gctattgaag
     9901 ctattgtaga ctacaaagat aaggatttgc agttagtagg cggtgagact cactgataac
     9961 ctaaaaagga tagtcaatta tgcttgttta ctaactatta actatgctaa atcaattgag
    10021 gttgtttaca taaaactcta tatcagagaa gcctgatata gagttttttc ttgctagttt
    10081 taggattttc ttgtaaaata gaaaaagtga agagaggtat gaaatgagca agaaagataa
    10141 aaaaatcgaa attcaagtag cggatgccaa agttaatgtt ggtaaagaca gttttgaagg
    10201 ttatacattg actatcggta aaaaagttat cggagaaatt gccgaattag acggacaatt
    10261 tgccattata aagaatggga atgtcgatag tttttataaa aaattggaaa aagctgtgga
    10321 aattttgatt gaaaattata atttagcaaa ataagtcttg tttttttgaa attttcatga
    10381 tataatagtc catgttgatt gtaggagaga tagcgaagag gctaaacgcg gcggactgta
    10441 aatccgctcc ttcgggttcg ggggttcgaa tccctctctc tccatttcat taatggggta
    10501 tagccaagcg gtaaggcaag ggactttgac tccctcatgc gttggttcga atccagctac
    10561 cccagttctt aggtaataat caagataaaa agcaaaatat cttagggtat tttattttta
    10621 taattgaaag acgtgaatga tatgaacatg tccttgcggg tgcttaggaa aaaaattata
    10681 agtatgtcaa gtttaagaaa aacttgattg ttggaggatt ttttagatga acgaatttga
    10741 agatttgcta aatagcgtta gtcaagttga gactggtgat gttgttagtg ctgaagtatt
    10801 gacagttgat gcgactcaag ctaacgttgc aatctctgga actggtgttg aaggtgtctt
    10861 gactcttcgc gaattgacaa acgatcgtga tgcagatatc aatgactttg ttaaagtagg
    10921 agaagtattg gatgttcttg tacttcgtca agtagttggt aaagatactg atacagttac
    10981 ataccttgta tctaaaaaac gccttgaagc tcgcaaagca tgggacaaac ttgttggtcg
    11041 cgaagaagaa gttgttactg ttaaaggaac gcgtgccgtt aaaggtggac tttcagtaga
    11101 atttgaaggt gttcgtggat ttatcccagc ttcaatgttg gatactcgtt tcgtacgtaa
    11161 cgctgagcgt tttgtaggtc aagaatttga tactaaaatc aaagaagtta acgctaaaga
    11221 aaaccgcttc atcctttcac gtcgtgaagt tgttgaagca gctactgcag cagctcgcgc
    11281 tgaagtattc ggtaaattgg ctgttggtga tgttgtaact ggtaaagttg ctcgtatcac
    11341 aagcttcggc gctttcatcg accttggtgg tgttgacgga ttggttcact tgactgaatt
    11401 gtcacatgaa cgtaacgtat caccaaaatc agttgtaact gttggtgaag aaattgaagt
    11461 gaaaatcctt gatcttaacg aagaagaagg acgtgtatca ctttcactta aagcaacagt
    11521 accaggacca tgggatggcg ttgagcaaaa attggctaaa ggtgatgtag tagaaggaac
    11581 agttaaacgt ttgactgact tcggtgcatt tgttgaagta ttgccaggta tcgatggact
    11641 tgttcacgta tcacaaattt cacacaaacg gattgaaaat ccaaaagaag ctcttaaagt
    11701 tggtcaagaa gttcaagtta aagttcttga agttaacgca gatgcagaac gcgtgtcact
    11761 ttctattaaa gctcttgaag aacgtccagc ccaagaagaa ggacaaaaag aagaaaaacg
    11821 tgctgctcgt ccacgtcgtc caagacgtca agaaaagcgt gatttcgaac ttccagaaac
    11881 acaaacagga ttttcaatgg ctgatttgtt tggtgatatc gaactttaat caaattgaaa
    11941 attcacaaaa tcctttgttt actaaacaag ggatttttct tttgtctctg ctcctttttt
    12001 gatataatag ttctatgtta aaatcagaaa aacaatcacg ttatcaaatg ttaaatgaag
    12061 aattgtcctt cctattggaa ggcgaaacca atgttttggc taatctttcc aacgccagtg
    12121 ctcttataaa atcacgtttt cctaataccg tatttgcagg cttttatttg ttcgatggaa
    12181 aggaattggt tttaggtccc ttccaaggag gtgtttcctg catccgtatt gcactaggca
    12241 agggtgtttg tggtgaggca gctcactttc aggaaactgt tattgttgga gatgtgacga
    12301 cctatctcaa ctatatttct tgtgatagtc tagctaaaag tgaaattgtg gtgccgatga
    12361 tgaagaatgg tcagttactt ggagttctgg atctggattc ttcagagatt gaggattacg
    12421 atgctatgga tcgagattat ttggaacaat ttgtcgctat tttgcttgaa aagacaacat
    12481 gggactttac gatgtttgag gaaaaatctt aatgtatcaa gcactttatc gaaaatatag
    12541 aagtcaaaac ttctcccagt tagttggtca agaagttgtg gctaagactc ttaaacaagc
    12601 ggtggagcaa gagaaaataa gtcacgctta tcttttttct ggtcctcgtg gaacgggaaa
    12661 aaccagtgtt gctaaaatct ttgccaaggc tatgaactgt cccaatcaag tgggtggcga
    12721 accttgcaat aactgctata tttgtcaagc agtgacggac ggtagtttag aagatgtcat
    12781 tgaaatggat gcagcttcta ataatggggt agatgaaatt cgcgaaattc gtgataaatc
    12841 tacctatgcg cctagccttg ctcgttataa ggtttatatc atagatgagg ttcacatgct
    12901 gtctacaggg gcttttaatg ccctcctaaa gacgctggaa gaaccaacac agaatgtagt
    12961 ctttattttg gccactactg aattacacaa gattcctgct actattctat cccgtgtgca
    13021 acgttttgag tttaaatcaa ttaagacaca ggatattaag gaacatattc actatatctt
    13081 agaaaaagaa aatatcagtt ctgaaccaga ggctgtggaa atcattgcca gacgggcgga
    13141 aggtggaatg cgggacgcct tgtctatttt ggatcaagcc ctgagtttga cacagggaaa
    13201 tgagctgacg actgctatct ctgaagaaat tactggcact attagcctat cagccttgga
    13261 tgattatgtg gcggccttgt ctcaacagga tgttcccaaa gctttgtctt gcttgaatct
    13321 tctttttgac aatggtaaga gcatgactcg ttttgtgacc gatcttttgc actatttaag
    13381 agacttgtta attgttcaaa cagggggaga aaatactcat catagttcag tctttgtaga
    13441 aaatttggca cttcctcaaa aaaatctgtt tgaaatgatt cgcttagcaa cagtgagttt
    13501 agcagatatt aagtctagtt tgcagcccaa gatttatgct gaaatgatga ccgtccgttt
    13561 ggcggaaatc aagcccgaac cagctctatc aggagcggtt gaaaatgaaa ttgctacgct
    13621 gagacaggaa gttgcccgtc tcaaacaaga gctttctaat gtaggtgcgg ttcctaaaca
    13681 agttgcacca gctcctagtc gaccagctac gggcaaaaca gtctatcgtg tcgatcgcaa
    13741 taaagtgcaa tctatcttac aagaggccgt cgaaaatcct gatttagcac gtcaaaatct
    13801 aattcgtttg cagaatgcct ggggagaggt aattgaaagt ctaggtgggc cggacaaggc
    13861 tctgctagtt ggttctcaac cggttgctgc caatgaacac catgctattc ttgcttttga
    13921 gtctaacttc aatgctggtc aaactatgaa acgagacaat ctcaatacca tgtttggcaa
    13981 tatcctcagt caggcggcag gtttttcacc tgagatttta gctatttcca tggaggaatg
    14041 gaaagaagtt cgcgcagcct tttcagccaa agccaaatct tctcaaactg aaaaagaagt
    14101 agaagaaagc ctgattccag aaggatttga atttttggct gataaagtga aggtagagga
    14161 agactaaaga aagatttcgt gatacaataa gtttatgaat aaacaacaat ttattattat
    14221 ggcgctgttt acagctgctg agacctattt tttcaatgaa gcctggatga ctggccgcta
    14281 tattatggca gccttttggg caattttact ctttagaaat ttccgagtca gttatgtgat
    14341 gggcaaaatc gttgatgtca tcgatcagca ttttaatagg aaagactagc cctcagcttc
    14401 cagacaaaat caaagccttt taggcttttt tttgttatac tagaaaagta tatttataga
    14461 atttttgctc tatttctggg gaaatcagac gtttttctag taagtactgt aaaagttttg
    14521 aaaaagaaag gaactatcat gtcagtatta gagatcaaag atcttcacgt tgagattgaa
    14581 ggaaaagaaa ttttaaaagg ggttaacctg accctgaaaa caggagaaat tgccgctatc
    14641 atgggaccaa atggtacagg taaatcgact ctttctgccg ctatcatggg aaatccaaac
    14701 tatgaagtaa ctaaaggtga agttttgttt gatggcgtaa acatccttga gttggaagtg
    14761 gatgagcgtg cgcgtatggg acttttcctt gctatgcaat acccatcaga aatccctgga
    14821 attaccaatg ctgagtttct tcgtgccgct atgaatgcgg gtaaagaaga tgatgagaag
    14881 atttcagttc gtgagtttat tactaggcta gatgaaaaaa tggaattgct caacatgaaa
    14941 gaagaaatgg cagagcgtta cctcaacgaa ggcttctctg gtggtgagaa aaaacgcaat
    15001 gaaattcttc aacttttgat gttggagcca acatttgctc ttttggacga gattgactca
    15061 ggtcttgata ttgacgctct taaagttgtg tctaaaggtg tcaatgccat gcgtggtgaa
    15121 ggttttggtg ctatgatcat cactcactac caacgtcttt tgaactatat cacacctgat
    15181 gtggtacacg tgatgatgga aggtcgtgtt gtcctttctg gtggtccaga attggctgcg
    15241 cgtttggaac gtgaaggata cgcaaaatta gctgaagaac ttggctacga ctacaaggaa
    15301 gaattgtaat ttcctcgtat cttttaggag aagtaaatga ctagagaaaa tattaaactt
    15361 ttttcagaaa tgcacgctga accaagctgg ttggctgatc tccgtcaaaa agcttttgac
    15421 aagattgaga ctttggaatt accagttatt gagcgtgtca aattccaccg ttggaatctg
    15481 ggtgatggaa cgattacaga aaatgagcca tcagcaaatg ttccagattt cacagcttta
    15541 gatcatcact tgaagttggt gcaagtagga actcaaactg ttttcgaaca aactccagtt
    15601 gagttagctg aacagggtgt tgtcttcaca gactttcact cagctttaga agaaattcca
    15661 gagctgatcg aagaattctt catgtcatct gttaagtatg atgatgacaa gttggcggct
    15721 taccacacag cttactttaa cagtggtgct gtactctata ttccagataa cgtagaaatc
    15781 acagagccaa ttgaaggaat tttctaccaa gatagcgata gcaatgtgcc gtttaacaag
    15841 catattatga ttatcgctgg taaaaattct aagattaatt atctggagcg tttagagtca
    15901 cgcggtgaag gaagtgccaa agcaactgct aatatcacag tagaagtgat tgcacgttca
    15961 ggtgcgcaag tcaagtttgc tgctatcgac cgtctaggtg aaaacgtcac tgcctacatt
    16021 agccgtcgtg gtaaattagg caacgatgca agtattgact gggctatcgg tgtcatgaac
    16081 gaaggaaatg tcgttgctga ttttgatagt gacttgattg gtaatggtag ctatgctgac
    16141 ctcaaggttg tagctctttc aagtggtcgt caggtacaag ggattgatac tcgtgtaact
    16201 aactatggct gcaactctat cggaaatatc ctacaacatg gggttatcct tgaaaaagca
    16261 actttgactt tcaatggtat cggccacatc atcaagggtg ctaagggagc agatgcccaa
    16321 caagagagcc gtgttctcat gctttcagac caagcgcgtt cagatgctaa cccaattctt
    16381 ttgattgatg aaaatgatgt cactgcagga cacgcagcgt ctatcggaca agttgatcca
    16441 gaagacatgt attacctcat gagtcgtgga ttggataagg caactgcaga gcgtttggtt
    16501 gttcgtggtt tccttggatc tgttatcgtg gagattccag tcaaggaagt tcgtgatgaa
    16561 atgattgcaa ctatcgaaga gaaattgtca aaacgctaag gggaagccta tgttagatgt
    16621 agaagcgatt cgcaaggatt ttccaatttt agatcagatt gtcaatgatg aacctctggt
    16681 ctatctggac aatgctgcga cgacacaaaa accactagta gttctgaaag ctattaacag
    16741 ttactatgag caggacaatg ccaatgttca ccgtggtgtc cataccttag cggaacgagc
    16801 gacagcttct tatgaagctg ctcgtgaaac cattcgtaag tttattaatg caggctctac
    16861 aaaggaagtt ctctttacca gaggaacgac aaccagcctt aactgggtgg cacgctttgc
    16921 tgaggaaatt ctcactgagg gagaccaggt cttgatttca gtaatggaac accattctaa
    16981 tatcattcca tggcaggaag cttgtcgaaa gactggagca gagcttgtct atgtctatct
    17041 taaagacggt gccttggata tggaggattt gcgagctaaa ttgactgata aggttaaatt
    17101 tgtttcccta gctcatgcct ccaatgttct tggtgtggtc aatccgatca aggaaatcac
    17161 tcaattagcc caccaagttg gggcaatcat ggtagtggat ggtgctcaat ctacacctca
    17221 tatgaagatt gatgtccagg acttggatct ggactttttc gccttttcgg gtcacaagat
    17281 ggctggtccg actggtatcg gtgtccttta cggcaaagaa aagtatcttg agcaaatgtc
    17341 tccagtagaa tttggcggcg agatgattga ttttgtctac gagcaatccg ctagttggaa
    17401 ggaattgcct tggaaatttg aggctggaac gccaaatatg gcaggagcta ttggacttgc
    17461 gactgcagtt gattatctgg aaaagattgg tatggatgcc gttgaagctc atgaacagga
    17521 attgattgcg tacgtctatc caaaactgca ggcaattgag ggattgacca tttacggttc
    17581 tcaggatttg gctcaacgtt cgggtgttat tgcctttaac ctaggtgatc tccatcctca
    17641 cgatcttgcg acggctctgg attatgaagg agtggctgtt cgtgctggtc accattgtgc
    17701 gcaacccttg cttcagtatt tggaagtccc agcatcagct cgtgcaagtt tttatatcta
    17761 taataccaag gcagattgcg acaaactagt cgatgcccta caaaagacaa aggagttttt
    17821 caatggcact ttctaaacta gatagccttt atatggcagt ggtagcagac cattcgaaaa
    17881 atccacatca ccaagggaag ttagaagacg ctgagcaaat cagtctcaac aatccgactt
    17941 gtggggatgt catcaacctc tctgtcaagt ttgatgcaga ggaccgtttg gaagatattg
    18001 cttttctaaa ttcaggatgc acgatttcaa ctgcttctgc tagtatgatg acagatgccg
    18061 ttttaggaaa aaccaaacaa gaaattttag aactggcgac tattttttct gaaatggttc
    18121 aagggcaaaa agatgagcgt caagaccaac ttggagacgc ggcattcttg tcaggtgttg
    18181 ccaaattccc tcaaagaatc aagtgtgcaa ccctagcttg gaatgccctt aagaaaacaa
    18241 ttgaaaatca agaaaaacag taagacaagt ttcttttgtc ttatgaatta ttagaaatga
    18301 agaaaggata ttatggctga agaaagagta gaaccaaaac caattgacct tggtgaatat
    18361 aaatttggtt tccatgacga tgtagagcct gtcttatcga caggaaaagg actcaacgaa
    18421 ggtgttattc gtgaattatc tgctgctaag ggtgagcctg agtggatgtt ggagttccgt
    18481 ttgaagtctt atgaaacctt caaaaaaatg cccatgcaaa cttggggagc agacttgtca
    18541 gagattgact ttgatgactt aatctactac caaaaaccat ctgacaaacc agcccgttct
    18601 tgggatgatg tacctgaaaa gattaaagaa acctttgaac gtatcgggat tccagaagct
    18661 gaacgtgctt atttagcagg ggcttctgcc cagtacgagt cagaagtggt ttaccacaac
    18721 atgaaggaag agttccaaaa attaggtatt atctttacag atacagattc cgcactcaag
    18781 gaatacccag acttatttaa acaatacttt gcgaagttgg taccgccgac agataacaag
    18841 ttggcagccc tcaactcagc agtatggtcg ggtggaactt ttatctacgt gccaaaaggt
    18901 gtcaaggtag atattccact tcaaacttat ttccgtatca ataacgaaaa tataggtcag
    18961 ttcgaacgta ccttgattat cgttgatgag ggagcaagcg tccactacgt agaaggatgt
    19021 acagcaccaa catattcaag caatagcttg cacgctgcca ttgtagaaat ttttgctttg
    19081 gacggagctt atatgcgtta tacaactatc caaaactggt ctgataacgt ctataacttg
    19141 gtaacaaagc gtgctaaggc tcaaaaggat gccactgttg agtggattga tggaaacttg
    19201 ggtgccaaaa cgactatgaa atatccatct gtttatcttg atggagaagg agcgcgtggt
    19261 accatgctct ctatcgcctt tgctaatgca gggcaacacc aagacacggg tgctaagatg
    19321 attcacaatg ctccacatac cagctcgtct attgtgtcta aatccatcgc taaaggtgga
    19381 ggaaaggttg actaccgtgg acaagtcacc tttaacaaga actctaagaa atctgtttcc
    19441 cacattgaat gtgataccat tatcatggat gacttgtcag catcagatac tattccattt
    19501 aatgaaattc acaactcgca agtggctttg gaacacgaag ccaaagtatc taagatttca
    19561 gaagagcaat tgtattatct catgagccgt ggattgtcag aatctgaggc aactgaaatg
    19621 attgtcatgg gatttgtaga accctttaca aaagaacttc caatggaata cgcagttgag
    19681 ctgaaccgct tgattagcta tgaaatggag ggatcagttg gataaaattt gattttatac
    19741 tcttcgaaaa tctcttcaaa ccacgtcagc atcgccttac cgtatgtatg gttactgact
    19801 tcgtcagttt catctacaac ctcaaaacag tgttttgagc aacctgcggc tagcttccta
    19861 gtttattctt tgattttgag tattagattt actcaaaatc aaggattttg aagatgaact
    19921 tgtatcaaaa aatcgcggtt taaaatcgcg attttttata atttctcgtt aacaaagcgg
    19981 acaaactgat tccaccaaac ttttaagaag aaggcttttt caattttctt gtctgctacc
    20041 atttcgaaac tagggcgctc tgtggtgatg taaccttgac caatcaagtc cttgtcttca
    20101 taagtcaaat ggccaaccac tgttccagct tcaagtggtg ctgggattgc tttggaatca
    20161 ggtgtgaatt gaacagattg ggaagattga ttcccaacac gttcgattag atagatatcc
    20221 tctggagcca ctgcagttac tgtatcttct tttccatctt gtacaggggc tttgctatct
    20281 tgataggcat cgccttgttg aacgattttg cgaagtgtaa atgtagaaga aatataatcc
    20341 attagggaag atgtagctgt aaatcgagcg taaggattat tgtcttgatg atctgcattt
    20401 aaaacaactg tgatgactct catgcctttt tcgacagtag taccaacaaa agactctcca
    20461 gccttatctg ttgttcctgt ttttagccca tcaaaaccac cacggtaagc aggcatacct
    20521 tctaacatgt agttggttga agtgattgtc atcccagcaa aagtagaaga aggttttttg
    20581 gtgatttcta agacttgtgg gtattttttg atgaggttgc gagcaacgat agcgacatca
    20641 taagcactaa gcttattttc ctcatctttt ttagaacctg ggtaaatgtt atcccctaga
    20701 gtttcattgt taagacctgt cgtattgaca acagtggcat cctgaattcc ccattccaag
    20761 agttttgccc gcatcatatc gatgaaatct ttttctgagc cagcaatttt ctcagctagg
    20821 gcaatagcgg cgctgttggc actagatacc agagttgctt caagcaactc ttcgacagta
    20881 taattacggg cctccatagg aatattactg gcttcagaat ttgtcgtcaa ttgataagga
    20941 taatcagaaa tatctacagg agtggagagg gtaatacttc cgttttccaa agcttcatag
    21001 accagataag cagtaatcaa ttttgttatg gaagcaattt cgacaggttg cgttgcatcc
    21061 ttctcataga gaattttacc agtatttgcc tcaacagcaa tcgcatgttt agcggcaatg
    21121 gtaaaatctt gagcaacagc agtagaagca ccccctaaaa gagagacagt taacaaagtt
    21181 aaaaatattt ttttcatagt agtcttattc tatcataaag aaaaaaaata ttcttgcttt
    21241 aataattcat ctgttaagct ttttgaaaat atggtaaaat aaagtgaggg aggtaactca
    21301 tgtttcgtag aaataaatta tttttttgga ccacagaaat tttactctta accatcatct
    21361 tttacctatg gagacagatg gggtctttga ttaacccttt tgttagcgtg cttaatacaa
    21421 ttatgattcc atttttatta gggggctttc tttattattt gacaaaccct attgttactt
    21481 tcttaaataa agtctgtaaa ctcaatcgtt tgcttggtat tttaattacc ttgtgtactt
    21541 tggtctgggg aatggtcata ggtgttgtct atctcttacc tattttgatt aatcagttat
    21601 ctagtttgat tatatctagt caaactattt atagtcgagt acaagactta atcatagact
    21661 tatctaatta tcctgcgctc cagaatttgg atgtagaagc tacaattcag cagttaaact
    21721 tatcctatgt tgatattctt caaaatatcc taaatagcgt atcaaatagt gtggggagcg
    21781 tcttgtcagc tcttatcagt actgttttga ttttgattat gactccagtt tttttggttt
    21841 atttcttatt agatggacat aaattcttgc ccatgcttga aagaacgatt ctaaagaggg
    21901 atcgcttgca tattgcaggc ttattaaaga atttaaatgc gacgattgct cgctatatta
    21961 gtggagtttc gattgacgca atcattatag gttgtttggc ttatattggc tatagtatta
    22021 ttggtttaaa atatgcttta gtttttgcca ttttttctgg tgtagccaat ttaattcctt
    22081 atgtggggcc aagtattggt ttgattccta tgatcatcgc aaatatattc actgatcccc
    22141 atagactgct gattgcagtg atttatatgc ttgttgttca gcaggtagat ggcaatatct
    22201 tatatcctcg aatcgtagga agtgttatga aggttcatcc aatcacgatt ttagttttac
    22261 ttttgttgtc aagcaatatc tatggtgtag ttggaatgat tgtcgcagtg ccaacctatt
    22321 ctatcttgaa agaaatttct aagttcttat cccgtttgta tgaaaatcat aaaataatga
    22381 aagaacgaga aagagaatta gctaagtaaa agtcaggaga accctgattt ttctttactg
    22441 gaagtggcct ttagattaga agactgaaaa taagttaaag tcttaaacta attttcacag
    22501 ctaagaatag tagaagttaa tctgataaaa atcgaaaaaa ccagtggaat tctgtgtcag
    22561 ggtaagttcc actggttttc atagtctatt aaagttcgaa tgaaacctat ttatagtaga
    22621 ttgaaactag aatagtacac ctctaattct aaaacattgt tagaaatcga tttgactgtc
    22681 ctgatctatt cgttctattc ttatttcatt ttactatatt ttggtgcaat aagtgaaaag
    22741 tagtccgaat aatataagga ttgattttat agtttttaaa ctcaaatgaa ttgaaataaa
    22801 gagagtacga aaattctcat ctgaaagtat tttagaataa ttctcttcgt gaatttcttc
    22861 aaaacagata gcttcatctt aggtatgtga tttctttttg catttttgag ttagataagg
    22921 tataatggtt ttattgtctt ttggggtcgt tacggattcg acaggcatta tgaggcatat
    22981 tttgcgactc gtgtggcgac gtaaacgctc agttaaatat aactgcaaaa aataacactt
    23041 cttacgctct agctgcctaa aaaccagcag gcgtgacccg atttggattg ctcgtgttca
    23101 atgacaggtc ttattattag cgagatacga ttaagccttg tctagcggtt tgataagaga
    23161 ttgatagact cgcagtttct agacttgagt tatgtgtcga ggggctgtta aaataataca
    23221 taacctatgg ttgtagacaa atatgttggc aggtgtttgg acgtgggttc gactcccacc
    23281 ggctccatta ttcctttgca ttcttttgca ttccttggta aaacgttgtt aaatcaacgt
    23341 tttttatttt tatctttggt attcctttgc attcttttgc taaaaaggga gtcacaaaca
    23401 gaccctattt taaaaaaagg atagaaaaaa ggatacaaca tttgtcgcat cctaaaaata
    23461 atcttttttc cacggaagac atgggattcg aacccacgca cgctattaca cgcctaccgc
    23521 gtttccaaca cggcctctta agcctcttga gtaatcttcc aatacttact caaatagtct
    23581 accataaagg ctcttatctt gcaataaaaa ttctagaaat aagaaaaatg atagattttg
    23641 aaagaaaatg ataaaaaatg cttgacttca aaagaaagta tgatagaatg aatagtgtaa
    23701 acgataacag gaggtgattc ggtgttaaaa acagagcgga agcaactgat tttagaggag
    23761 ttaaatcaac atcatgtagt ttctctagaa aaattagtta gtttgctaga aacgtcagaa
    23821 tcaacggttc gaagagactt ggatgagttg gaagcggaaa acaagcttcg tcgtgtgcat
    23881 ggtggagcag aactccccca ctccttacag gaagaagaaa ccattcaaga aaaatctgtc
    23941 aaaaaccttc aagaaaagaa gttgctggct cagaaagcag cctctctcat taaagaaaaa
    24001 gatgtcatct ttatcgatgc tggaacaaca actgcttttt tgattcatga attggtcaat
    24061 aagaatatta cagttgtgac caactccatt caccatgccg ctcagttggt tgaaaagcag
    24121 attccaactg tcatggttgg aggaaacgtc aagacggcga cagatgctag tatcggtggc
    24181 gttgctctta accagattaa ccaattgcac tttgaccgtg cctttatcgg aatgaatggt
    24241 gttgacgatg gctattatac gactcctgat atggaggagg gagctgtgaa aagagctatt
    24301 ttggagaatg ccaagcagac ctacgtcttg gtggattcgt caaaaattgg acaaacttgc
    24361 tttgccaagg tagcaccact caaacgcgct atcgttatca ctagtcaagg gcatgagctc
    24421 ttgcaggtta ttaaggagaa aacggaggta atagaagtat gatttataca gtcacactca
    24481 atccatccat tgactatatc gttcgtttgg accaagtcaa agttggtagt gtaaatcgta
    24541 tggacagtga tgataagttt gctggtggga aaggaatcaa tgtcagccgt gtcttgaaac
    24601 gtttgaatat accaaataca gcgacgggat ttatcggtgg ctttactggt aaatttatca
    24661 cagatacttt agcagaggaa gaaatcgaga cacgttttgt ccaggtggca gaagatactc
    24721 gtatcaatgt taaaatcaaa gcagaccaag aaacagaaat caacggaacg ggtccaactg
    24781 ttgaatcggt tcagctagaa gaattgaaag ctattttatc tagtctgaca gcagaagata
    24841 cagttgtctt tgcaggttca agtgctaaaa atctaggcaa tgttatctat aaggatttga
    24901 tttccttgac gcgccagact ggtgcgcaag tggtctgtga ctttgaagga cagaccttaa
    24961 ttgatagttt ggactaccag cctcttcttg taaaaccaaa caatcatgaa cttggagcga
    25021 tttttggggt taaactcgaa agtttagatg aaattgagaa atacgctcgt gagttactgg
    25081 ctaagggtgc tcaaaatgtt attatctcta tggctggtga tggtgccctt cttgtcacat
    25141 ctgagggagc ttacttcgct aaaccaatca aaggaacagt caaaaattca gttggagctg
    25201 gtgattctat ggttgctgga ttcacaggtg aatttgtcaa atcaaaagac gtagtagaag
    25261 ccttcaaatg gggagtggct tgcggaacgg caactacctt ctcagatgac ttggcaacgg
    25321 cggaatttat taaagaaaca tatggaaaag ttgaggtaga aaaacgatga aaattcaaga
    25381 cctattgaga aaagatgtca tgttgctaga tttgcaggca actgaaaaaa cagctgtcat
    25441 cgacgagatg attaaaaatt tgacagacca cggttatgta acagattttg aaacatttaa
    25501 agaaggaatt ttggcgcgtg aagctttgac ttctactggt ttgggtgatg gaatcgcaat
    25561 gcctcacagc aaaaacgctg ctgtcaaaga agcgacagtt ctatttgcta agtcaaataa
    25621 gggtgttgac tacgagagct tggatggaca agcaactgac ctcttcttca tgattgcagc
    25681 tccagaaggt gccaatgata ctcacttggc agccttggca gaattgtctc aatacttgat
    25741 gaaagacggt tttgcagaca aacttcgtca agcaacatct gcagaccaag ttatcgaact
    25801 ttttgaccaa gcttcagaaa aaactgagga acttgttcaa gcacctgcta atgactctgg
    25861 tgactttatc gtagctgtta cagcttgtac aacaggtatt gcccacactt acatggccca
    25921 agaagccctt caaaaagtag ctgctgaaat gggggttggt atcaaggtcg aaaccaacgg
    25981 tgctagcggt gttggaaatc aactaactgc agaagatatc cgtaaggcta aagctattat
    26041 cattgcagca gacaaggccg ttgaaatgga tcgatttgat ggaaaaccat tgatcaatcg
    26101 tccagttgct gacggtatcc gtaagacaga agagctaatt aacttggctc tttcaggaga
    26161 tactgaagtc taccgtgccg ctaatggtgc caaagctgca acagcctcta acgaaaaaca
    26221 aagccttggt ggtgccttgt acaaacactt gatgagtggt gtatctcaaa tgttaccatt
    26281 cgttatcggt ggtggtatca tgattgccct tgccttcttg attgacggtg ctttgggtgt
    26341 tccaaatgaa aaccttggca atcttggttc ttaccatgag ttagcttcta tgttcatgaa
    26401 aattggtgga gctgcctttg gtttgatgct tccagtcttt gcgggttatg ttgcctactc
    26461 tattgctgaa aaaccgggtt tggtagcagg tttcgtggct ggtgctattg ccaaagaagg
    26521 ttttgccttt ggtaaaattc cttatgccgc aggtggtgaa gcaacttcaa ctcttgcagg
    26581 tgtctcatct ggtttcctag gtgcccttgt tggtggattt atcgcaggtg ccttggttct
    26641 tgccatcaag aaatacgtta aagttcctcg ttcactcgaa ggtgctaaat caatccttct
    26701 attgccactt cttggaacaa tcttgacagg atttgttatg ctagctgtga atatcccaat
    26761 ggctgcaatc aacactgcta tgaatgactt cctaggcggt cttggaggag gttcagctgt
    26821 ccttcttggt atcgtccttg gtggaatgat ggctgttgac atgggtggac cagttaataa
    26881 agcagcttat gtctttggta caggtacgct tgcagcaact gtttcttcag gtggttctgt
    26941 agccatggca gcagttatgg ctggaggaat ggtgccacca cttgcaatct ttgtcgcaac
    27001 tcttcttttc aaagataaat ttactaagga agaacgtaac tctggtttga caaacatcat
    27061 catgggcttg tcatttatca ctgagggagc gattccattt ggtgccgctg acccagctcg
    27121 tgcgattcca agcttcatcc ttggttcagc agtagcaggt ggactcgttg gtcttactgg
    27181 tatcaaactc atggcgccac acggaggaat cttcgttatc gcccttactt caaatgctct
    27241 cctttacctc gtttctgtct tggtaggagc aatcgtaagt ggtgtggttt atggttacct
    27301 acgcaaacca caagcataaa aaatagaaaa atgaaaagat tggaccgttt ggtgcagtct
    27361 ttttctcttc ccgaaatgcc tgtgaaatat ggtataatag aagaatggca aacaagaata
    27421 caagtacaac aagacggaga ccgtctaaag cagaactgga aagaaaagaa gcgattcaac
    27481 gaatgttgat ttcgttagga attgcgattt tattgatttt cgcagccttc aaattagggg
    27541 ctgcaggtat aaccctttat aatttaattc gcttgctagt gggtagccta gcttatctgg
    27601 cgatattcgg cctattaatc tatctcttct ttttcaagtg gatacgaaaa caggaaggac
    27661 tcttatctgg ctttttcacc atatttgctg gcttactctt gatttttgag gcctacttgg
    27721 tttggaaata tggtttggac aagtccgttc taaaagggac catggctcag gttgtgacag
    27781 atctgactgg ttttcgaacg actagctttg ctggaggggg cttgatcggg gtcgctcttt
    27841 atattccaac agcctttctc ttttcaaata tcggaactta ctttattggt tctatcttga
    27901 ttttagtggg ttctctccta gtcagccctt ggtctgttta cgatattgct gaatttttca
    27961 gtagaggctt tgccaaatgg tgggaagggc acgagcgtcg aaaagaggaa cgctttgtca
    28021 aacaagaaga aaaagctcgc caaaaggctg agaaagaggc tagattagaa caagaagaga
    28081 ctgaaaaagc cttactcgat ttgcctcctg ttgatatgga aacgggtgaa attctgacag
    28141 aggaagctgt tcaaaatctt ccacctattc cagaagaaaa gtgggtggaa ccagaaatca
    28201 tcctgcctca agctgaactt aaattccctg aacaggaaga tgactcagat gacgaagatg
    28261 ttcaggtcga tttttcagcc aaagaagccc ttgaatacaa acttccaagc ttacaactct
    28321 ttgcaccaga taaaccaaaa gatcagtcta aagagaagaa aattgtcaga gaaaatatca
    28381 aaatcttaga agcaaccttt gctagctttg gtattaaggt aacagttgaa cgggccgaaa
    28441 ttgggccatc agtgaccaag tatgaagtca agccggctgt tggtgtaagg gtcaaccgca
    28501 tttccaatct atcagatgac ctcgctctag ccttggctgc caaagatgtc cggattgaag
    28561 caccaatccc tgggaaatcc ctaatcggaa ttgaagtgcc caactccgat attgccactg
    28621 tatctttccg agaactatgg gaacaatcgc aaacgaaagc agaaaatttc ttggaaattc
    28681 ctttagggaa ggctgttaat ggaaccgcaa gagcttttga cctttctaaa atgccccact
    28741 tgctagttgc aggttcaacg ggttcaggga agtcagtagc agttaacggc attattgcta
    28801 gcattctcat gaaggcgaga ccagatcaag ttaaatttat gatggtcgat cccaagatgg
    28861 ttgagttatc tgtttacaat gatattcccc acctcttgat tccagtcgtg accaatccac
    28921 gcaaagccag caaggctctg caaaaggttg tggatgaaat ggaaaaccgt tatgaactct
    28981 ttgccaaggt gggagttcgg aatattgcag gttttaatgc caaggtagaa gagttcaatt
    29041 cccagtctga gtacaagcaa attccgctac cattcattgt cgtgattgtg gatgagttgg
    29101 ctgacctcat gatggtggcc agcaaggaag tggaagatgc tatcatccgt cttgggcaga
    29161 aggcgcgtgc tgcaggtatc cacatgattc ttgcaactca gcgtccatct gttgatgtca
    29221 tctctggttt gattaaggcc aatgttccat ctcgtgtagc atttgcggtt tcatcaggaa
    29281 cagactcccg tacgattttg gatgaaaatg gagcagaaaa acttcttggt cgaggagaca
    29341 tgctctttaa accgattgat gaaaatcatc cagttcgtct ccaaggctcc tttatctcgg
    29401 atgacgatgt tgagcgcatt gtgaacttca tcaagactca ggcagatgca gactacgatg
    29461 agagttttga tccaggtgag gtttctgaaa atgaaggaga attttcggat ggagatgctg
    29521 gtggtgatcc gctttttgaa gaagctaagt ctttggttat cgaaacacag aaagccagtg
    29581 cgtctatgat tcagcgtcgt ttatcagttg gatttaaccg tgcgacccgt ctcatggaag
    29641 aactggagat agcaggtgtc atcggtccag ctgaaggtac caaacctcga aaagtgttac
    29701 aacaataaaa aaatagcttc tttccaagtt tggagggaag ctattttagt ggctattgat
    29761 tgcttttatt ttctgaagtt ggcgcattgg actgtttttc gttttcagta gcaggtttac
    29821 ttgaagcagg agtagaagag tcctgagttg ctgttttctg atcttctttt ttctcttcct
    29881 tgacgctaga ttttggtgtt tcctcttgct gtgttttttc ttgactagtg ttagtctctt
    29941 tagttggact ggtgttttcc ttaggggatt ccttttggat ttctttgaca atggttgtcg
    30001 tctggcttgt cgtaggttct tttttaatat ttttgttatt atccaaggcg ttcataatcg
    30061 tgatacttgc ggtaatcaag ccaaggatac tagcgattgt agcaacggtt ttttgaaaga
    30121 ctgtaaagcc ttttttgatg tgttctgttt ttggttttga agttctacga tagttagaca
    30181 tacattctct cctttgatta tgatttatta tactctgttt ctttaaaaaa atcttaaaaa
    30241 aagagaaatt tccctttctt gtcgcaagct ccgtttcatg atacaataga ggaagtgatt
    30301 ttagaaagcg tgagaaacat gatttacttt gataattcag cgacgaccaa gccttatcct
    30361 gaagcccttg aaacctatat gcaggtcgct tcaaaaattt taggaaaccc atctagtctc
    30421 catcgtttgg gagaccaagc aacacgaatc ttagatgctt ctcgccaaca gattgcagat
    30481 ttaatcggta agaaaagcga tgaaatcttc tttacctcgg gtggaacaga aggggataac
    30541 tggcttatca agggtgtggc ctttgaaaaa gctcagtttg gcaagcacat cattgtttca
    30601 gccattgaac atccagcagt caaagagtca gccctctggt tgaaaagtca aggatttgaa
    30661 gtggattttg ctccagttga taagaaaggc ttggtcgatg ttgaggcgtt agcaggtttg
    30721 atacggcatg atacaatcct cgtttccatc atggctgtga acaatgaaat cggctctatc
    30781 caacctattg aggctatttc agaattcttg gcagacaagc cgactatttc cttccacgtt
    30841 gatgcggttc aggcgcttgc caaaattccg actgaaaagt atctgacaga acgggtggat
    30901 tgcgcgactt tctctagtca caagttccac ggggttcgag gtgttggctt tgtctatatc
    30961 aaatctggca agaagattac acctcttctt acaggtggtg gccaggagcg agattatcgt
    31021 tcgacaactg aaaatgtggc agggattgca gcgacagcca aggccctccg tttgtctatg
    31081 gaaaagctag atatctttag gagcaagact gggcagatga aggcagtgat tcgccaagct
    31141 cttctgaact atccggatat ttttgtcttt tcagatgagg aaaactttgc acctcatatt
    31201 ctgacttttg gaatcaaagg tgttcgaggt gaagtcatcg ttcacgcctt tgaagactat
    31261 gatattttca tctcaacaac ctcagcttgt tcatctaagg caggaaaacc agccggtacc
    31321 ttgattgcca tgggagtgga caaagataag gccaagtcag ctgtgcgtct tagcctagac
    31381 ttggaaaatg atatgagtca ggtcgagcag tttttgacca agttaaaatt gatttacaat
    31441 caaactagaa aagtaagata ggagcattca tgcagtattc agaaattatg attcgctacg
    31501 gagagttgtc aaccaagggt aaaaaccgta tgcgtttcat caataaactt cgtaataata
    31561 tttcggacgt tttgtctatc tatacccaag ttaaggtaac agcagatcgc gaccgtgccc
    31621 acgcttacct caatggagct gattacacag cagttgcaga atctctcaaa caagtttttg
    31681 gaattcaaaa cttttctcct gtttataagg ttgaaaaatc tgtagaagtt ttgaagtctt
    31741 ctgtccaaga gattatgcgg gacatctaca aggaaggtat gacctttaag atttctagca
    31801 agcgtagcga ccacaacttt gaacttgata gtcgtgaact caaccaaaca cttggagggg
    31861 ctgtattcga agccattcca aatgtgcaag ttcaaatgaa aagtcctgac atcaatcttc
    31921 aggtggagat tcgtgaagaa gcagcctatc tttcttatga aaccattcgt ggggctggtg
    31981 gtttgccagt tggaacttca ggtaaaggga tgctcatgtt gtcaggaggg attgactcac
    32041 ctgtagcagg ttatcttgct cttaagcgtg gggtggatat cgaggcagtt cactttgcta
    32101 gtccaccata tactagtcct ggtgccctca agaaagcgca ggacttgacc cgtaaattga
    32161 ccaagtttgg cggaaatatc cagtttatag aggtgccttt cacagagatt caagaggaaa
    32221 tcaaagccaa agcgccagaa gcttatttga tgactctaac tcgtcgcttt atgatgcgga
    32281 ttactgaccg tattcgtgag gtacgaaatg gtttggttat catcaatggg gaaagtctag
    32341 gtcaagtagc cagccaaacc cttgaaagta tgaaggctat caatgctgtt accaacactc
    32401 ccatcattcg tcctgtggtt accatggaca agttggaaat cattgacatc gcccaggaaa
    32461 tcgatacctt tgacatttca atccaaccgt ttgaagactg ttgtaccatt tttgcaccag
    32521 atcgtccaaa aacaaatcct aaaattaaga atgcggagca gtacgaagcg cgtatggatg
    32581 ttgaaggctt ggttgagcga gcagtggctg gaatcatgat tactgaaatc acacctcaag
    32641 ccgaaaaaga tgaagttgat gacttgattg acaatctgct ctaattcaga aaatccaaaa
    32701 gaatagcgaa aatcagtaaa aaaagttagt tttttctcta aaaacaggta aaaaactaac
    32761 tttttttatt tttatgatat aatgatataa aattttgaat atagagagtt ttctgacaat
    32821 gaatcaatcc tacttttatc taaaaatgaa agaacacaaa ctcaaggttc cttatacagg
    32881 taaggagcgc cgtgtacgta ttcttcttcc taaagattat gagaaagata cagaccgttc
    32941 ctatcctgtt gtatactttc atgacgggca aaatgttttt aatagcaaag agtctttcat
    33001 tggacattca tggaagatta tcccagctat caaacgaaat ccggatatca gtcgcatgat
    33061 tgtcgttgct attgacaatg atggtatggg gcggatgaat gagtatgcgg cttggaagtt
    33121 ccaagaatct cctatcccag ggcagcagtt tggtggtaag ggtgtggagt atgctgagtt
    33181 tgtcatggag gtggtcaagc cttttatcga tgagacctat cgtacaaaag cagactgcca
    33241 gcatacggct atgattggtt cctcactagg aggcaatatt acccagttta tcggtttgga
    33301 ataccaagac caaattggtt gcttgggcgt tttttcatct gcaaactggc tccaccaaga
    33361 agcctttaac cgctatttcg agtgccagaa actatcgcct gaccagcgca tcttcatcta
    33421 tgtaggaaca gaagaagcag atgatacaga caagaccttg atggatggca atatcaaaca
    33481 agcctatatc gactcgtcgc tttgctatta ccatgatttg atagcagggg gagtacatct
    33541 ggataatctt gtgctaaaag ttcagtctgg tgccatccat agtgaaatcc cttggtcaga
    33601 aaatctacca gattgtctga gattttttgc agaaaaatgg taagttaaga aaggaaaaaa
    33661 cgaaatgcat attgaacatc ttagccactg gagtggtcat cttaaccgtg aaatgtacct
    33721 taaccgttat ggacatggtg ggattccagt tgtggtcttt gcttcatcag gtggtagtca
    33781 caacgaatac tatgattttg gcatgattga tgcctgtgct tcctttatcg aggaaggcct
    33841 tgtccagttc tttaccctat ctagtttgga tagtgagagc tggttggcta cttggaaaaa
    33901 tgctcatgac caagcggaaa tgcaccgtgc ctacgaacgt tatgtgattg aggaggccat
    33961 tcttttatca agcacaagac aggttggttt gatggcatga tgacgacagg ttgctctatg
    34021 ggagcctatc atgcactcaa tttcttcctc cagcatccag atgtctttac caaagtgatt
    34081 gctctcagtg gtgtttacga cgcacgtttc tttgtcggtg attactacaa cgatgatgct
    34141 atttaccaaa actcgccagt agattatatt tggaaccaaa acgacggctg gtttattgac
    34201 cgttaccgtc aggcagagat tgtgctgtgt acggggcttg gagcctggga acaagatggt
    34261 ttgccatcct tttacaagct caaagaagcc tttgacaaga aacaaattcc agcctggttt
    34321 gctgaatggg gacatgatgt cgcccatgac tgggaatggt ggcgtaaaca aatgccttat
    34381 ttcctcggta atctctattt ataaaaggag ttacctatga attaccttgt tatttctccc
    34441 tactatccac aaaactttca acagtttacc atcgaactag ctaataaagg catcacagtc
    34501 ttgggaattg gtcaagagtc ttacgagcaa ttggatgagc ccttgcgcaa tagcttgacc
    34561 gagtattttc gtgttgataa tcttgagaac atagatgaag tcaaacgtgc agttgctttt
    34621 ctcttttata aacatggtcc aattggccgc atcgagtctc acaatgaata ctggcttgag
    34681 ctagacgcaa cactcagaga acaattcaat gtttttggtg ccaaaccaga ggatctcaaa
    34741 aagacgaaat ataagtctga aatgaagaaa cttttcaaaa aagcaggtgt tcctgtggta
    34801 cctggagctg ttatcaagac ggaagcagat gttgatcaag cagtgaaaga aatcggtctt
    34861 ccaatgattg ccaaacctga taatggagtg ggagcagccg caacctttaa acttgagaca
    34921 gaagacgata tcaatcactt caagcaagaa tgggaccatt caacccttta tttctttgaa
    34981 aaatttgtca cttccagcga aatctgtacc tttgacgggc tcgtggacaa ggatggaaag
    35041 attgtcttct caacaacctt tgactacgcc tatacaccgc ttgacctcat gatttataag
    35101 atggacaatt cttattatgt gctcaaggat atggatccta aactgcgcaa gtatggggaa
    35161 gcaattgtca aagaatttgg tatgaaagaa cggtttttcc atattgagtt cttccgtgag
    35221 ggggacgatt atattaccat cgagtacaat aaccgccctg caggtggttt taccattgat
    35281 gtttataact ttgctcattc cttggacctt tatcgtggct atgcagctat tgtcgcagga
    35341 gaggagttcc cggcgtcaga ctttgaaact cagtattgtt tggctacttc tcgccgtgca
    35401 aatgctcact atgtttattc agaagaggat ttgcttgcca aatatagcca gcagttcaag
    35461 gttaaaaaag tcatgccagc tgccttcgcg gaacttcaag gagattacct gtatatgctg
    35521 accactccga gtcgacaaga aatggagcag atgattgcag atttcggaca acgtcaagaa
    35581 taagaactat cggattaagg aaattaactc ccttaatcct tttgttttgt ctgataaaaa
    35641 ataagagcat cccaacaagg tagctatcat aaaacttgtt cgataactat ttgaagcagg
    35701 attaggtggt cagaaattaa attttaatat ttcaattgag tcatagtatt gtgtttgcgt
    35761 atccttaaat cagctaaaag gatccatgac gacacctata cgatatagtt ttcaagatac
    35821 caaacaagtc tattaatatt caatgaaaat caaagagcaa actaggaagc tagccgcagg
    35881 tttctcaaaa cactgttttg aggttgtgga tagaactgac agagtcagta tcatatacct
    35941 acggcaaggt gaagctgacg tggtttgaag agattttcga agagtataaa atattcaggt
    36001 gacgcataga tatagttaat tgaagctttg tttgaaatct gataaaataa tgatattact
    36061 aagttttaaa aactaaagaa aagggaagat atgattacag gcgaattaaa aaataaaatc
    36121 gatcagctgt gggaaattct ttggacagaa ggaaacgcaa atcctttaac aaatattgaa
    36181 cagttgactt atctcttatt tatgaaagat ttggatagtg tcgagcttgg acgtgaaagt
    36241 gatgctgaat ttctagggat tccttatgag ggagtttttc caaaagataa acctgaatac
    36301 cgttggtcaa cttttaaaaa tataggagat gctcaggaag tttatcgttt aatgactcag
    36361 gagatttttc cgtttattaa aaatctcaag ggggatacag atgatacagc cttttcacga
    36421 tatatgcgag aagctatttt tcaaataaat aaacctgcta cgcttcaaaa ggcaatttct
    36481 atcttagatg tttttccaac taggggatta gatgtagatt ttgataatga caaacaaagt
    36541 attactgata tcggagatat ctatgaatat ctgttatcaa aattgtcgac cgcaggtaaa
    36601 aatggacagt tccgtacacc tcgtcacatc atcgatatga tggttgagtt gatgcaaccg
    36661 actatcaaag atatcatctc agatcccgct atgggttctg ctggcttctt agtatctgct
    36721 agccgttact taaagcgtaa gaaagatgaa tgggaaacca atacagataa tatcaatcat
    36781 tttcataatc agatgtttca tggaaatgat acggatacga ctatgttgag acttggggcg
    36841 atgaacatga tgctacatgg agtagaaaat ccacaaatca gttaccttga ctcgctgtct
    36901 caagataatg aagaagccga taaatatact ttggttttag caaatcctcc ttttaagggc
    36961 tcacttgact acaattcaac ctctaatgac cttcttgcaa ccgtaaaaac caaaaaaaca
    37021 gaattactct ttctttctct tttcttgcga actttaaaac caggtggacg agcagcagtt
    37081 atcgtacctg atggtgtcct ttttggttcg tctaaagctc ataaaggaat tcgtcaggaa
    37141 attgtagaga atcataagct tgatgctgta atctcaatgc ctagtggtgt gttcaagcct
    37201 tatgctggag tttcaactgc cattctcatc tttacaaaaa ctggtaatgg tggtactgac
    37261 aaagtctggt tttacgatat gaaagcggat ggtttaagtt tggatgataa gcgacaaccg
    37321 attagcgaca atgatattcc agatattatc gaacgctttc atcatcttga aaaagaagca
    37381 gaacgtcaga gaacggatca atctttcttt gttccagttg ctgagataaa ggaaaatgat
    37441 tatgatttgt ctatcaataa atataaagag attgagtatg aaaaagttga gtatgaacca
    37501 acagaggtca tcttaaagaa aatcaatgat ttagaaaaag aaattcaagc tggcttggct
    37561 gaattagaaa aattactcaa gtagagaggt ggctgtatga aaaaagtgaa gttgggggaa
    37621 gtcttatctc taaaaaaagg caagaaagcc actgtacttg ctgaacaaac aactctaagc
    37681 caacgttata ttcaaataga tgatttaaga aataataata atttaaaatt cactgaaagt
    37741 ttaaatatga ctgaagcact cccagatgat attctgatag catgggatgg agctaatgca
    37801 ggaacagttg gttatggatt atcgggagct gttggtagta caattacggt cttaaaaaag
    37861 aatgagcgat acaaagaaaa aattatatca gattacttgg gagtcttttt ggaaagtaaa
    37921 tcgcagtatt tacgagaaca ttcaacaggt gcaacaattc ctcatttaaa caagaatata
    37981 ttacttgatt tacaattaga attgctaggt atcgaagaac aagagaacat tatctgtatt
    38041 cttaatacga ttaaaaggct tattactaaa agaaaattgc agttagatga actaaacttg
    38101 ctcgtcaaat cccgatttaa cgagatgttt ggggatgtta ttctaaatga aaaagaatgg
    38161 aaagttagca aatggaacga gattctaaca ataagaaatg gtaaaaatca aaaacaggtt
    38221 gaagatgctg atgggaaatt tcctatttat ggaagtgggg gaattatggg atatgctaaa
    38281 gattggatag tgaagaaaaa ttcagttatt attggacgta aaggaaatat aaataaacct
    38341 attttagtta gagaaaattt ttggaatgta gatacagcat ttggattaga gcctgtttta
    38401 gaaaaaataa actcagaata tttattctat ttttgtcaat tatacaattt tgagaagtta
    38461 aataaggctg taacaatacc tagtttaact aaatcagatt tattaaatat ttccatcccc
    38521 ctccccccac tagccctcca aaatgagttc gcagactttg tagccctggt cgacaaatca
    38581 caatttgctt gtgagatagc tataaaagtg tggagaaata gcttgaaatt tagtataata
    38641 tagctaaact atttgtttaa agtgagaaaa aaatgggaaa ttttagcttt cttttaaaaa
    38701 atgacgaata tgaatctttt tcaaaacctt gcattgaagc tgagaatatg attgctacat
    38761 caactgtggc tactgccttt atggcgcgtc gtgctttaga gcaggctgtc cattggatat
    38821 atagtcacga ttcatattta gaagctccct atcgtgctac tctatcttct ttagtatggg
    38881 atgatgattt tagggatatc gtagattctg aactccacaa gcagatagtt ctgttgattc
    38941 ggtggggaaa ccatgctgct catggtggtg aaattaagga acgagaagcg attttagctt
    39001 tgcatcattt gtatcagttt gttaatttta tcgattattg ttacagcaat gagtttgtgg
    39061 agcgttattt tgatgagaag tgcttaccac tttcagcaaa catcaaatac cgagaaactc
    39121 cacaatctat gataaagtta caagacagtt taccagaact gcctgatttt catgaacaga
    39181 tggctgctca gtccgtagaa gttcaagaga cttatactga aaaacgtgag actgcagcgc
    39241 aacggcaaga tgtgcctttc catattgatc aattatctga ggcagagaca agaaagctct
    39301 ttattgatat cgatctccgt ttagcaggat ggatatttga agaaaactgt cgtgttgaga
    39361 tagccgttga tggtctcaag cacggttcag gaattggtta ctgtgactat gtactttatg
    39421 gtaaaaatgg gaaaatttta gcgattgtgg aggctaaaaa agcctctgtc aatccagaag
    39481 taggggaagt acaggtcaaa gaatatgctg aagctttgga gaaacatatc ggctatcagc
    39541 caatttgctt tattacaaat gggttgaagc actatatact tgatggtccg aaccgccgcc
    39601 agattgcagg cttttactct caagaagaat tgcaattagt gatggataga cgtcatcttc
    39661 aaaaaccgct tgaggatatt tctagtaaaa ttagggacga tatttccggg cgtcactacc
    39721 aaaaacatgc cattgcaagc gtttgtgaag ctttctctga tcatcgtaga caggcacttt
    39781 tggttatggc aactggggcg gggaaaactc gtacagcagt ttctctagtt gatatcttat
    39841 cacgtcataa ctgggtaaaa aacgttctct tcttagccga tagaacttcc ttggttaagc
    39901 aagcatatga ttcgtttaga aaattactcc cagatctttc cgtttgtaac ttcttagaag
    39961 ataaagaagg agctcaatca agtcgaatgg tcttttcaac ttatccgacc atgattggag
    40021 cgattagtgg tcaagaagaa gtaaatcaac gcccttttac tgttgggcat tttgacctta
    40081 tcataattga cgaatctcac cgttctattt atcagaaata caagtccatt tttgattatt
    40141 ttgatgcaag gattgtaggc ttaacagcta ctccgcgtca agatttagat aaaaacacct
    40201 atggattctt taatttggag aatggggttc caacatatgc atatgatttg gaagaggctg
    40261 ttaaagacgg atatttagta gcctatcatt ctatcgaaac caaactgaaa ctacctacgg
    40321 atggtctaca ttatgatgat ttgtccgaag aagaaaagga acattttgat agcaaatttg
    40381 aagacgatag ctgtgaaaaa gatattgatg ggagtgtgtt taattccttt attttcaata
    40441 aaagtacagt agaaattgtt ttaaatgaac tcatgacaag aggaattcag acagcctcgg
    40501 gtgatgaaat tggtaaaact attatttttg ctaaaaatca tgaccatgcg gaatatatca
    40561 gaggtatttt taacaaccgc tatcctgaaa aagggagcga ctatgctcag gtgattgatt
    40621 atagtattaa gcattatcag accttgattg atgattttaa aattaaggag aagtatcctc
    40681 aaattgcgat ttctgtcgat atgttagata caggtattga tgtaccagag gttgttaatt
    40741 tagtcttctt caagaaagta cgctctaaaa ctaagttttg gcagatgatt ggtcgaggaa
    40801 cccgtctatg taaagattta tttggacctg agcaggataa ggaaaacttc ttggtatttg
    40861 attatgggga caattttgat tattttcgtg cagatccaag agatggagag ggtcgtcaca
    40921 ttgtttcgct gactcagcgt ttatttaata tcaaagtgga cttgattcga gaacttcagg
    40981 gactccaata ccaagaagat cagtttgcga gagcataccg tcagcagctt gtctcggaac
    41041 ttcaaggtcg tatagagagc ttaaatgagt tggacttcag ggttcgtatg gttttagata
    41101 cagtttatag ctataggaaa ttggaaagtt ggcagaatct aactgctgtt acaagtgaaa
    41161 ccattcaaaa aaatctctct ccgcttttat ttgatgaaga taaagaagat gagatggcga
    41221 ggagatttga tttgtggttg cttcatattc agttggggca actgacagct aaatcttcca
    41281 ctgttcatat ttcccaagtg atgaagacgg ctagagctct ttctgctatt ggcaatatcc
    41341 cgcaggtttt tgagcaggct gaaattatgg ctctttgtca actgtagtgg gttgaaaaaa
    41401 agctaagctt gagaaaggac aaattt
//
LOCUS       DAVBCA010000012        40470 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.012, whole genome shotgun sequence.
ACCESSION   DAVBCA010000012 DAVBCA010000000
VERSION     DAVBCA010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40470)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40470)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40470
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.012"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            230..460
                     /gene="blpU"
                     /locus_tag="VQU19_000584"
     CDS             230..460
                     /gene="blpU"
                     /locus_tag="VQU19_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HET2479876.1"
                     /translation="MNTKKMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAVRGLQ
                     LGIKTRTWQGAATGAAGGAILGGVAYAATCWW"
     gene            1175..3328
                     /locus_tag="VQU19_000585"
     CDS             1175..3328
                     /locus_tag="VQU19_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HET2479877.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPYKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTGINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            3341..4690
                     /locus_tag="VQU19_000586"
     CDS             3341..4690
                     /locus_tag="VQU19_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HET2479878.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAMETGASLASQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            4861..5568
                     /locus_tag="VQU19_000587"
     CDS             4861..5568
                     /locus_tag="VQU19_000587"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HET2479879.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIAGDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQELK"
     gene            5770..9495
                     /locus_tag="VQU19_000588"
     CDS             5770..9495
                     /locus_tag="VQU19_000588"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HET2479880.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQGTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDTFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEASQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKIG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEDANSTSPTLFYNDANQHVTKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            9588..11030
                     /locus_tag="VQU19_000589"
     CDS             9588..11030
                     /locus_tag="VQU19_000589"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HET2479881.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     RDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            11067..12089
                     /locus_tag="VQU19_000590"
     CDS             11067..12089
                     /locus_tag="VQU19_000590"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HET2479882.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            12086..12631
                     /gene="purN"
                     /locus_tag="VQU19_000591"
     CDS             12086..12631
                     /gene="purN"
                     /locus_tag="VQU19_000591"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HET2479883.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKADYEAALVELLEEHQIALVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            12715..13224
                     /locus_tag="VQU19_000592"
     CDS             12715..13224
                     /locus_tag="VQU19_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HET2479884.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLIFFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            13249..14796
                     /gene="purH"
                     /locus_tag="VQU19_000593"
     CDS             13249..14796
                     /gene="purH"
                     /locus_tag="VQU19_000593"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HET2479885.1"
                     /translation="MTKRVLISVSDKADIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDGVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYDDAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGENKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLDGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            14918..16180
                     /gene="purD"
                     /locus_tag="VQU19_000594"
     CDS             14918..16180
                     /gene="purD"
                     /locus_tag="VQU19_000594"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HET2479886.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVSETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFFEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGMIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNITWTDKGVTLGVVVA
                     SKGYPLNYSKGVELPVKTDGDIITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            16583..17071
                     /gene="purE"
                     /locus_tag="VQU19_000595"
     CDS             16583..17071
                     /gene="purE"
                     /locus_tag="VQU19_000595"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HET2479887.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            17058..18149
                     /gene="purK"
                     /locus_tag="VQU19_000596"
     CDS             17058..18149
                     /gene="purK"
                     /locus_tag="VQU19_000596"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HET2479888.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEAD
                     LEAAYALADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLADKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEQYVTENSSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVDELGEGIDF"
     gene            18159..18386
                     /locus_tag="VQU19_000597"
     CDS             18159..18386
                     /locus_tag="VQU19_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HET2479889.1"
                     /translation="MIQIIVNTFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIEKEEFE"
     gene            18449..19747
                     /gene="purB"
                     /locus_tag="VQU19_000598"
     CDS             18449..19747
                     /gene="purB"
                     /locus_tag="VQU19_000598"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HET2479890.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(19802..23740)
                     /gene="strH"
                     /locus_tag="VQU19_000599"
     CDS             complement(19802..23740)
                     /gene="strH"
                     /locus_tag="VQU19_000599"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HET2479891.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKAEVVTPTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEDDKPETEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKESARTVNLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGSMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQTLNEVPKDLNRY
                     TAESVAAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEAQKEEEAKR
                     EVEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLDDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGGG
                     FLKKAIENTGKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTL
                     VANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESG
                     LAPTTEVKPRLDIQKEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPA
                     EESKALPQDPAPVVIEKKLPETGTHDSAGLVVAGLMATLAAYGLTKRKED"
     gene            complement(24055..24771)
                     /locus_tag="VQU19_000600"
     CDS             complement(24055..24771)
                     /locus_tag="VQU19_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET2479892.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            25119..26906
                     /locus_tag="VQU19_000601"
     CDS             25119..26906
                     /locus_tag="VQU19_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HET2479893.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPVYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            26903..27379
                     /locus_tag="VQU19_000602"
     CDS             26903..27379
                     /locus_tag="VQU19_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HET2479894.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            27407..28312
                     /locus_tag="VQU19_000603"
     CDS             27407..28312
                     /locus_tag="VQU19_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET2479895.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            28299..29114
                     /locus_tag="VQU19_000604"
     CDS             28299..29114
                     /locus_tag="VQU19_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET2479896.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            29121..29525
                     /locus_tag="VQU19_000605"
     CDS             29121..29525
                     /locus_tag="VQU19_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET2479897.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            29824..30990
                     /locus_tag="VQU19_000606"
     CDS             29824..30990
                     /locus_tag="VQU19_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HET2479898.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVAKPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCAADGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTTLLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVVLGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            31106..32143
                     /locus_tag="VQU19_000607"
     CDS             31106..32143
                     /locus_tag="VQU19_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HET2479899.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHIYNGALLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            32351..33205
                     /locus_tag="VQU19_000608"
     CDS             32351..33205
                     /locus_tag="VQU19_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET2479900.1"
                     /translation="MTYEYKSHIYLAETALNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREYYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLEDKFSVPSASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKKELLTIAQRAQEVDAPIKWMTSSQLEITDSDGI
                     VTRIRLAR"
     gene            33355..33612
                     /locus_tag="VQU19_000609"
     CDS             33355..33612
                     /locus_tag="VQU19_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HET2479901.1"
                     /translation="MTNSKYITCLKRSEGQLCGIQKMIEGDRDCADIVTQLTAVRSSV
                     ERVIEMIITENLTECINQPLDDSEAQKERLEKAIRYLIKRK"
     gene            complement(33988..34080)
                     /locus_tag="VQU19_000610"
                     /pseudo
     CDS             complement(33988..34080)
                     /locus_tag="VQU19_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(34116..34412)
                     /locus_tag="VQU19_000611"
     CDS             complement(34116..34412)
                     /locus_tag="VQU19_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET2479902.1"
                     /translation="METSISMADFYGKYQNENLELIDVREAHEFQAGHAPGAKNLPLS
                     TLEQGYKELKPDHEYYVICQGGVRSASTCQFLISQGLTVTNVEGGMNAWPGQVE"
     gene            complement(34402..34563)
                     /locus_tag="VQU19_000612"
     CDS             complement(34402..34563)
                     /locus_tag="VQU19_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(FAD)-dependent dehydrogenase"
                     /protein_id="HET2479903.1"
                     /translation="MDKKQAYIVSCHSGLRSYIAEPILKQAGFTAQNLDGAYSLYKMV
                     NPEGVEYGN"
     gene            34633..35397
                     /locus_tag="VQU19_000613"
     CDS             34633..35397
                     /locus_tag="VQU19_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HET2479904.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLDEEI
                     DRYAREVGADCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPSRYMEMQPEAIAAIEEVLE
                     DRGIPYEEVMTWTTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            36010..37389
                     /locus_tag="VQU19_000614"
     CDS             36010..37389
                     /locus_tag="VQU19_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HET2479905.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLI
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            37403..38068
                     /locus_tag="VQU19_000615"
     CDS             37403..38068
                     /locus_tag="VQU19_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HET2479906.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            38182..38277
                     /locus_tag="VQU19_000616"
                     /pseudo
     CDS             38182..38277
                     /locus_tag="VQU19_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            38423..38872
                     /locus_tag="VQU19_000617"
     CDS             38423..38872
                     /locus_tag="VQU19_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET2479907.1"
                     /translation="MKLLSIAISSYNAAAYLHYCVESLVIGGEQVGILIINDGSQDQT
                     QEIAECLASKYPNIVRAIYQENKCHGGAVNRGLAEASGRYFKVVDSDDWVDPRAYLKI
                     LETLQELESKGQEVDAFVTNFVYEKEGQSRKKSMSYESVLPVRQIFD"
     gene            39029..39439
                     /locus_tag="VQU19_000618"
     CDS             39029..39439
                     /locus_tag="VQU19_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HET2479908.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKRIDQQLKVNRLLVDQLD
                     LSQVSHPKMREYLLNHIEITTVISSTLLNRSETAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            39555..>40470
                     /gene="pavB"
                     /locus_tag="VQU19_000619"
     CDS             39555..>40470
                     /gene="pavB"
                     /locus_tag="VQU19_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HET2479909.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVEKAV"
BASE COUNT        11200 a         7822 c         9465 g        11983 t
ORIGIN      
        1 attatcaatc atgaactagg attctagttt tgcaggaagt ctaatagtaa aaaagtgatt
       61 agaaaacatc ttttttaaaa atagagatga ttttgaaaca aaaaagctaa ttcaagacgt
      121 ttcgatgcca attcaagatt tggatgaaaa aaattaatag atactgttat actaaacttg
      181 tcaagtttgt aacaagacaa atattaaaaa taaaaaagag gtattcgtta tgaatacaaa
      241 aaagatgtca caatttgaaa ttatggatac tgagatgctt gcttgcgttg aaggtggcgg
      301 atgcaattgg ggagattttg ccaaagcagg tgttggagga ggagcagtac gaggtcttca
      361 gctaggaatt aaaacaagaa catggcaagg tgcagcaact ggtgctgcgg gaggagctat
      421 acttggaggt gtggcctatg cagcgacatg ttggtggtaa ttatggattt taaaagtttt
      481 attattggtt tagtagttgg tatatttggt ccttatatgg atgatttaat tagaaaaaaa
      541 tttttaaagt cttcggagaa gaaaacagaa aaatctgtta aaaaataatc aaaactataa
      601 atgatgaatc tgaatcaaaa ttattttgcg catgtaaaga ggagtcttat agtaacgagt
      661 caaaaaagga gtaactatga atcgtaattt agaacggtgt tatctattct gactaggaat
      721 agatcatacc agaggtagct tagaaatagc agggacatta gaaattgaag taataaatag
      781 gatgtcgtaa gtgttactat caatgattta tttgtttcaa gcttgcctag ggtgacagta
      841 aaaaatcaat ttcctttcaa tagcatattt ttagtgggca ggactcttgt tctgcctatt
      901 tttttatcca aaaagtgcag ttgggaggga gataggctca tttgggaagg aagtccagtt
      961 tttgtttagt gattggggta agatagttgt tatcagatga gtttatactc ttcgaaaatc
     1021 aaattcaaac cacgtcaacg tcgccttgcc gtatatatgt gactgacttc gtcagtccta
     1081 tctacaacct caaaacagtg ttttgagcag cctgcggcta gtttcctagt ttgctctttg
     1141 attttcattg agtattaggg aaaaggagat gaatatgaaa tttgggaaac gtcactatcg
     1201 tccgcaagtg gatcagatgg actgcggtgt agcttcatta gccatggttt ttggctacta
     1261 tggtagttat tattttttgg ctcacttgcg agaattggct aagacgacca tggatgggac
     1321 gacggctttg ggcttggtca aggtggcaga ggagattggt tttgagacgc gagccattaa
     1381 ggcggatatg acgctttttg acttgccgga tttgactttt ccttttgttg cccatgtgct
     1441 taaggaaggg aaattgctcc actactatgt ggtgactggg caggataagg atagcattca
     1501 tattgccgat ccagatcccg gggtgaagtt gactaaactg ccacgtgagc gttttgagga
     1561 agaatggaca ggagtgactc tttttatggc acctagtcca gactataagc cttataagga
     1621 acaaaaaaat ggtctgctct cttttatccc tatattagtg aagcagcgtg gcttgattgc
     1681 caatatcgtt ttggcaacac tcttggtaac cgggattaac attgtgggtt cttattatct
     1741 gcagtctatc attgatacct atgtgccaga tcagatgcgt tcgacactag ggattatttc
     1801 tattgggcta gtcatcgtct acatcctcca gcaaatcttg tcttacgctc aggagtatct
     1861 cttgcttgtt ttggggcaac gcttgtcgat tgacgtgatt ttgtcctata tcaagcatgt
     1921 ttttcacctc cctatgtcct tctttgcgac acgcaggaca ggggagatcg tgtctcgttt
     1981 tacagatgct aacagtatca tcgatgcgct ggcttcgacc atcctttcga ttttcctaga
     2041 tgtgtcaacg gttgtcatta tttcccttgt tctattttca caaaatacca atctcttttt
     2101 catgacttta ttggcgcttc ctatctacac agtgattatc tttgccttta tgaagccgtt
     2161 tgaaaagatg aatcgggata ccatggaagc caatgcggtt ctgtcttctt ctatcattga
     2221 ggacatcaac ggtattgaga ctatcaagtc cttgaccagt gaaagtcagc gttaccaaaa
     2281 aattgacaag gaatttgtgg attatctgaa gaaatccttt acctatagtc gagcagagag
     2341 tcagcaaaag gctctgaaaa aggttgccca tctcttgctt aatgtcggca ttctctggat
     2401 gggggctgtt ctggtcatgg atggcaagat gagtttgggg cagttgatta cctataatac
     2461 cttgctggtt tactttacca atcctttgga aaatatcatc aatctgcaaa ccaagcttca
     2521 gacagcgcag gttgccaata accgtctaaa tgaagtgtat ctagtagctt ctgagtttga
     2581 ggagaagaaa acagttgagg atttgagctt gatgaaggga gatatgacct tcaagcaggt
     2641 tcattacaag tatggctatg gtcgagacgt cttgtcggat atcaatttaa ccgttcccca
     2701 agggtctaag gtggcttttg tggggatttc agggtcaggt aagacgactt tggccaagat
     2761 gatggttaat ttttacgacc caagtcaagg ggagattagt ctgggtggtg tcaatctcaa
     2821 tcagattgat aaaaaagccc tgcgccagta catcaactat ctgcctcaac agccctatgt
     2881 ctttaacgga acgattttgg agaatcttct tttgggagcc aaggagggga cgacacagga
     2941 agatatctta cgggcggtcg aattggcaga gattcgagag gatatcgagc gcatgccact
     3001 gaattatcag acagaattga cttcggatgg ggcagggatt tcaggtggtc aacgtcagag
     3061 aatcgctttg gcgcgtgctc tcttgacaga tgcgccggtc ttgattttgg atgaggcgac
     3121 tagcagtttg gatattttga cagagaagcg gattgtcgat aatctcatgg ctttggacaa
     3181 gaccttgatt ttcattgctc accgcttgac tattgctgag cggacagaga aggtggttgt
     3241 cttggatcag ggcaagattg tcgaagaagg aaagcatgct gatttgcttg cacagggagg
     3301 cttttacgcc catttggtca atagctagaa agaggagagg atgaaaccag aatttttaga
     3361 aagtgcggag ttttataatc gtcgttacca taatttttcc agtagtgtga ttgtacccat
     3421 ggcccttctg ctcgtgtttt tacttggctt tgcaactgtt gcagagaagg agatgagttt
     3481 gtccactaga gctactgtcg aacccagtcg tatccttgca aatatccagt caactagcaa
     3541 caatcgtatt cttgtcaatc atttggaaga aaataagctg gttaagaagg gggatctctt
     3601 ggttcaatac caagaagggg cagagggtgt ccaagcggag tcctatgcca gtcagttgga
     3661 catgctaaag gatcaaaaaa agcaattgga gtatctgcaa aagagcctgc aagaagggga
     3721 gaaccacttt ccagaggagg ataagtttgg ctaccaagcc acctttcgcg actacatcag
     3781 tcaagcaggc agtcttaggg ctagtacatc gcaacaaaat gagaccatcg cgtcccagaa
     3841 tgcagcagct agccaaaccc aagccgaaat cggcaacctc atcagtcaaa cagaggctaa
     3901 aattcgcgat taccagacag ctaagtcagc tatggaaaca ggtgcttcct tggccagtca
     3961 gaatctagcc tactctcttt accagtccta caagtctcag ggcgaggaaa atccccaaac
     4021 taaggttcag gcagttgcac aggttgaagc acagatttct cagttagaat ctagtcttgc
     4081 tacttaccgt gtccagtatg caggttcagg tacccagcaa gcctatgcgt cagggttaag
     4141 cagtcaattg gaatccctta aatcccaaca tttggcaaag gttggtcagg aattgaccct
     4201 tctagcccag aaaatcttgg aggcagagtc aggtaagaag gtacagggaa atcttttaga
     4261 caaggggaaa attacggcga gtgaggatgg ggtgcttcat cttaatcctg agaccagtga
     4321 ttctagcatg gttgcagaag gtgccctact agcccaactt tatccatctt tggaaagaga
     4381 agggaaagcc aaactcacag cctatctaag ttcaaaagat gtagcaagaa tcaaggtcgg
     4441 tgattctgtt cgctatacta cgactcatga tgccgggaat caacttttcc tagattctac
     4501 tattacaagt attgatgcga cagctactaa gactgagaaa gggaatttct ttaaaatcga
     4561 ggcggagact aatctaactt cggagcaggc tgaaaaactt aggtacgggg tggaaggccg
     4621 cttgcagatg attacgggca agaaaagtta tctacgttat tatttggatc aatttttgaa
     4681 caaagagtaa tgttcgtgtt tttagagtta aataattttt aaactgtgag aaagattctt
     4741 cttgcagttt tttctttaca atttttaaaa aaacatctgc tatttattcg gttaaattct
     4801 tgtgtttttt ggttttttgt ggtaaaatgt gctcaagtaa tacgaaaggc gaactttaaa
     4861 atgtcaaaac aattgatcta ttcgggaaaa gctaaagata tctatacaac tgaggatgaa
     4921 aatcttatta tttcaactta caaggaccag gcgactgctt tcaacggtgt caagaaggag
     4981 cagattgcag gtaagggagt cttgaataat cagatctcat cttttatttt tgagaaatta
     5041 aatgcggctg gtgtggcgac tcactttgtg gagaaacttt cagacacgga acaactcaat
     5101 aaaaaggtta agattattcc tttggaagtc gtgctccgca actatactgc tggttccttt
     5161 tcaaaacgtt ttggtgtgga tgagggaatc gccttggaga ctccgattgt cgaattttac
     5221 tacaaaaatg atgatttgga tgatccattt atcaatgatg agcatgtgaa attcctacag
     5281 attgcgggtg accagcagat tgcctacttg aaggaagaaa cgcgtcgtat caatgaacta
     5341 ttgaaagtct ggtttgctga gattgggctt aaattgattg actttaagct agagttcggt
     5401 tttgacaagg atggcaagat tatcttggca gacgaatttt caccagataa ctgccgcttg
     5461 tgggacgctg atggcaacca catggataag gatgttttcc gtagaggatt gggagaacta
     5521 accgacgttt atgagattgt ttgggaaaag ttgcaggaat tgaaataatc tgtttgcaac
     5581 ggaaaacctt cgtctctcaa ctaaaaggac tcaggctgaa aaggtccccc agaccttttc
     5641 actctgtaga gaactaggtg aactaacaga tgtttacgaa attgtctggg aaaagttgca
     5701 gggtttaaaa taacaacctc aaggctgttt gggaatattg caagagctga aataaaggaa
     5761 taagaattga tggataaacg tatttttgtt gaaaaaaagg ctgattttca ggtcaagtca
     5821 gagagtttgg ttagagagct ccagcacaac ttgggactgt caagcttgaa aagtattcgt
     5881 attgtgcaag tatatgatgt atttgacttg gctgaggact tgtttgcacc tgcagagaag
     5941 cacattttct ctgagcaggg aaccgaccat gttttagatg aagtatctgt gcaggcggat
     6001 cttgctaact atgctttctt tgccattgaa agtctgccag ggcagtttga ccagcgtgca
     6061 gcttcgtcac aggaagcctt gcttttgttg ggaagttcga gtgacgtgac agtcaacaca
     6121 gcccaacttt acttggtgaa taaagatatt gatgcgactg agttggaagc tgtcaaaaac
     6181 tacctgctca atccagttga ttctcgtttc aaggatatca cgacagggat tgccaagcag
     6241 gagttttcag agtcagacaa gaccattcca aaattgactt tctttgaaag ctatacagca
     6301 gaagactttg ctcgctacaa ggccgagcaa gggatggcca tggaagtgga tgatttgctc
     6361 tttatccaag actactttaa gtcaatcggg cgcgtgccaa ctgagactga actcaaggtt
     6421 ttggacactt actggtctga ccactgccgt catacgactt ttgagacaga gttgaaacac
     6481 atcgactttt cagcttctaa atttcaaaag caattgcagt caacctatga caagtatatt
     6541 gccatgcgcg aggagttagg tcggtctgaa aaaccacaaa ccttgatgga tatggcgact
     6601 attttcggtc gttatgagcg tgctaacgga cgattggatg atatggaagt ctctgacgaa
     6661 atcaatgcct gctcagttga aattgaagtg gatgttgatg gtgtcaagga accttggctc
     6721 ctcatgttta aaaatgaaac ccacaaccat ccaacagaaa ttgagccatt tggtggagcg
     6781 gctacctgta tcggtggagc tattcgtgat ccgttgtcag gccgttccta tgtttaccaa
     6841 gccatgcgta tttcaggtgc tggtgatatt acagcaccga tttcggaaac tcgtgctggg
     6901 aaattgccac aacaagtcat ttctaaaaca gcagctcatg gttattcttc atatggtaac
     6961 cagattgggc ttgccacaac ctacgttcgt gaatacttcc acccaggctt tgtagctaaa
     7021 cgtatggaac ttggtgccgt tgttggtgcg gctcccaagg gcaatgttgt ccgtgaaaaa
     7081 cctgaagcag gtgatgtgat catccttctc ggaggcaaaa caggtcgtga tggtgtcggt
     7141 ggtgcgacgg gctcttctaa ggttcaaaca gttgagtctg tagagactgc tggtgctgag
     7201 gttcaaaaag gaaatgccat cgaagaacgc aagattcagc gcctcttccg taatggcaat
     7261 gtcactcgtc tgatcaagaa gtccaatgac tttggggcag gcggcgtctg tgtggctatc
     7321 ggtgaattgg cagacggtct tgaaatcgac ctcaacaagg tgcctcttaa ataccagggc
     7381 ttgaatggta cagaaattgc catctctgaa tcacaagaac ggatggcggt cgtggttcgt
     7441 cctgaagatg tggatacctt cgttgccgaa tgtaacaaag aaaatattga tgctgttgtg
     7501 gtggcgacag taactgaaaa accaaatctt gtcatgcact ggaatggtga gacaatcgtt
     7561 gacttggagc gtcgtttcct tgacaccaat ggtgtgcgcg tggttgtcga tgccaaagtt
     7621 gtggacaagg atgtcaaact cccagaagag cgtcaaacat ctgctgaaac actggaatca
     7681 gataccctta cggttctatc tgacctcaac catgcaagtc aaaaaggatt acagactatc
     7741 tttgactgct ctgttggacg ctcaacggtt aatcacccac ttggtggtcg ttaccaactc
     7801 acaccaactg aggcatctgt gcagaaattg ccagttcaac acggtgtgac tcatactgcg
     7861 tcggtcattg ctcaaggttt caacccatat gtagctgaat ggtctccata ccacggtgct
     7921 gcttatgcgg ttatcgaagc aactgctcgt ttggtggctg ctggtgccaa ctggtctaag
     7981 gctcgtttct cttaccaaga atatttcgag cggatggaca agcaagcaga gcgtttcggt
     8041 cagccagtag ctgctcttct aggttctatt gaagcacaaa ttcagcttgg cttgccatct
     8101 atcggtggta aggactccat gtctggtacc tttgaagaat tgaccgttcc gccaaccttg
     8161 gttgcctttg gggtgacgac ggcagatagc cgtaaggtgc tctctccaga atttaaagct
     8221 gttggggaaa atatctacta catcccaggt caagccctct ctgcagagat tgattttgac
     8281 ttgattaaga aaaattttgc tcagtttgaa gcaagccaag ctgaccataa agtgacgtct
     8341 gcatcagctg tcaaatacgg tggtgtagtt gaaagtttgg ctcttgctac ctttggaaac
     8401 tatattggtg cagaggtgac cttgcctgaa cttaaaacag ctttgacagc tcaattaggc
     8461 ggctttgtct tcacatctcc tgaagaaatt gctggagtag agaagattgg acaaacgaaa
     8521 gcagacttta cactgactgt caacggtgtg aagctagatg gacacaagct tgacagtgca
     8581 tttcaaggga cattggaaga agtttaccca acagaattta cccaagcgaa agaactagaa
     8641 gaagtaccag ctgtggcatc agatgttgtg attaaagcca aagaaaaggt tgaaaaacct
     8701 gtggtttaca tcccagtctt tccaggaacc aactcagaat atgattcagc taaggccttc
     8761 gaaaaagaag gtgcagaggt caatttggtg ccattcgtga ccttgaatga agaagctatt
     8821 gtcaagtcag ttgaaactat ggttgacaat atcgacaaga ctaatattct cttctttgcc
     8881 ggtggattct cggctgcgga tgaaccagat ggttcagcta agtttatcgt caatatcctg
     8941 cttaatgaaa aagtgcgtgt ggctattgat agctttatcg cccgtggtgg cttgattatc
     9001 ggtatttgta atggattcca agccttagtc aaatcgggtc tcctaccata cggaaacttt
     9061 gaagatgcta acagtactag tccaaccctc ttctacaatg atgccaacca acacgtgacc
     9121 aagatggtgg aaactcgcat tgccaatacc aactcaccat ggttggctgg tgtgcaagtg
     9181 ggcgatatcc acgctattcc tgtttcgcac ggtgaaggga agtttgtcgt gacggctgag
     9241 gaatttgcag agctccgtga caatggacaa attttcagcc aatacgttga ctttaacggt
     9301 aaaccaagta tggattctaa gtacaatccg aatggttctg tccatgccat cgaaggaatt
     9361 accagcaaga atggtcaaat catcggtaag atgggccact cagaacgtta tgaggatggt
     9421 cttttccaaa atatcccagg caataaagac caacacctgt tcgcatcagc ggttaaacat
     9481 ttcactggaa aataagactt acagattttc taatagatag tatcagtaat gtaaaagtca
     9541 tgtaaatcta gctcttgatg attacaaatg aaaattaggt ataaaaaatg acatacgaag
     9601 taaaatctct taatgaagaa tgtggtgttt tcggtatttg gggacatcca gatgctgcta
     9661 agttgaccta ttttggactc cacagtcttc aacaccgtgg tcaggagggg gcaggaatcc
     9721 tctccaatga tcaaggacaa ctgaagcgcc atcgtgacat ggggctttta tcagaagttt
     9781 tcagaaatcc agccaatttg gataaattga caggagctgg tgcgattggg catgtgcgtt
     9841 atgcgactgc tggcgaagct tctgttgata acatccagcc cttcctcttc cgttttcacg
     9901 atatgcagtt tggcttggct cataatggaa atctgaccaa tgcagcctct ctcaagaaag
     9961 aactggaaca aagaggagca attttcagcg cgacttcgga ctctgaaatc ttggctcacc
    10021 tcattcgtcg tagtcataat cctagcctga tgggcaaaat caaggaagcg ctcagccttg
    10081 tcaaaggtgg ttttgcctat atcttgctgt ttgaggacaa gttgattgcg gctcttgacc
    10141 ctaatggctt tcgtccgctt tctatcggga aaatggccaa cggagcggtg gttgtttcct
    10201 ctgaaacctg tgcttttgag gtcattggtg ccgagtggat tcgtgatttg aagccaggtg
    10261 agattgtgat cattgatgac gagggcattc agtatgacag ctatacagat gatactcagt
    10321 tggcgatttg ttctatggag tatatctact ttgctcgccc tgattctaat atccacggtg
    10381 tcaatgtcca tacggcacgt aagagaatgg gagcgcaatt ggcgcgagaa tttaagcatg
    10441 aggcagatat tgtagttggt gtgcccaatt cttccctaag cgcggctatg ggatttgcgg
    10501 aagaatcagg cttaccaaat gaaatgggtc tgatcaaaaa ccaatacacc cagcgaactt
    10561 ttatccaacc gactcaagaa ttgcgggagc aaggagtgcg gatgaaactg tctgctgttt
    10621 cgggtgttgt caaaggcaaa cgtgtggtca tggtggatga ttccattgta cgtggaacaa
    10681 cctctcgtcg tatcgttcag ctcttgaaag aagcgggtgc gactgaggtt cacgttgcca
    10741 ttggaagtcc tgcactagcg tatccatgtt tctacgggat tgatatccag acccgtcagg
    10801 agctgattgc agccaatcat acggtcgaag aaactcgcca aatcattggt gcggacagtc
    10861 tgacttatct ttcaattgat ggcttgattg agtcgattgg tatcgaaaca gatgcgccga
    10921 acggtggtct ctgtgtcgct tactttgacg gtgactaccc aacgcctctc tatgactacg
    10981 aagaagacta tcgtagaagt ttggaagaaa agaccagttt ttacaagtag gcgacagatt
    11041 ctccattaaa gaaaaggaaa aaacaaatga caaataaaaa tgcatatgcc cagtcgggtg
    11101 tggatgttga agcgggttat gaagttgttg aacggattaa aaagcacgtg gcccgtacgg
    11161 agcgtgcagg tgtcatggga gctcttggtg gctttggtgg tatgtttgac ctttccaaga
    11221 ctggggttaa agaacccgtc ttgatttcag ggactgacgg tgtcggaacc aagctcatgt
    11281 tggctatcaa gtacgacaag cacgatacca tcgggcagga ctgtgtggcc atgtgtgtca
    11341 acgacatcat tgctgcaggt gcggaacccc tctattttct cgactacgta gcgacaggga
    11401 agaatgaacc agctaagcta gaacaagtgg ttgctggtgt ggcagaaggt tgtgtgcagg
    11461 ctggtgctgc cctcatcggt ggggaaacgg ctgaaatgcc gggcatgtac ggcgaagacg
    11521 actatgactt ggctggtttt gcggtcggtg tggctgaaaa atctcaaatc attgacggtt
    11581 caaaggtggt agagggagat gttcttctcg gacttgcttc aagtgggatt cactcaaatg
    11641 gttactcttt ggttcgtcgt gtctttgcgg attacacagg tgaggaagtc ctaccagaat
    11701 tggaaggcaa gaaacttaag gaagttctac ttgagccgac tcgtatctat gtcaaggctg
    11761 tcttgccgct catcaaagaa gagttggtca acggcattgc ccacatcaca ggtggtggct
    11821 ttatcgaaaa tgtccctcgt atgtttgcag atgacctagc tgctgaaatt gatgaaagca
    11881 aagttccagt gcttccaatt ttcaaagccc ttgaaaaata tggtcagatt aaacacgaag
    11941 aaatgtttga aatcttcaat atgggtgtgg gacttatgtt ggcggtcagc cctgaaaatg
    12001 tagagcgtgt aaaagaattg ttggatgaag cagtctatga aattggtcgc atcgtcaaga
    12061 aagaaaacga aagtgtcatt atcaaatgaa aaaaatagcg gtttttgcct ctggtaatgg
    12121 ctcaaatttt caggtgattg ccgaagaatt tccagtggag tttgtctttt cagaccatcg
    12181 tgatgcctat gtgcttgagc gtgcaaagca gctcggcgtt ctgtcctatg cttttgaact
    12241 caaggagttt gagagcaagg cagactacga agcagccctt gtcgaactct tggaagaaca
    12301 ccagattgcc ttggtttgcc tagcaggcta catgaaaatc gttggaccaa ccttattgtc
    12361 ggcttatgaa ggtcggattg tcaacattca tccagcctac ttgccagaat ttccaggagc
    12421 tcatgggatt gaggatgctt ggaatgctgg cgtgggtcag tctggtgtga ccattcactg
    12481 ggtggattcg ggtgtggata caggccaggt catcaaacag gttcgtgtgc cacgactagc
    12541 tgatgatacc attgacagat ttgaagctcg catccatgaa gcagagtaca ggttgtatcc
    12601 ggaagtagtg aaggctctat ttacagattg actttttgat gattcatatg atatctttga
    12661 ttttaaattg gagtcagtgt ttgttgaaga cggcttcaaa cggaggtatt tgtaatgtta
    12721 gaatctaaaa aaacaactcg atatgtattt tatgtctatc tgatgttatt aacttgggga
    12781 atcttattta agtttgaaac aaatcctgaa tttatagcat ttttcttagc tccaaggtat
    12841 atcaattgga ttccattttc agaaccacta atagtcgatg gaaaaattgt ttttgctgaa
    12901 atgttattta atctgatttt ctttattcca ttaggtgttt gtttcccttt gataaaaact
    12961 aatttatcta gtttaagaat agtcgggaca ggtttcttga ttagtttatt gtttgagtgc
    13021 ttacagtata ttttagcaat aggtataaca gatataacgg atttgacttt aaatacgcta
    13081 ggtgtctgtg taggcttact gatttatcaa atttttataa gagtgttcaa atcacagact
    13141 agaaaatgga tcaatatctt aggtatgctt agccttggtt ttgcttatct tgttttactg
    13201 ttactgcatt taattggtgt ttaactaatg attaaaaagg agaatataat gactaaacgc
    13261 gtcttaatca gcgtctcaga caaagcggac attgttgaat ttgcccaaga actcaaaaaa
    13321 cttggttggg agattatctc gacaggtgga actaaggttg cccttgataa tgctggggtg
    13381 gataccattg ctatcgatgg tgtgactggt ttcccagaaa tgatggacgg tcgtgtgaag
    13441 accctccacc caaatatcca cggagggctt ctcgctcgtc gtgacttgga tagccacttg
    13501 gaagcggcta aggacaacaa gattgagctc attgaccttg tggtggtcaa cctttaccca
    13561 tttaaggaaa ctatccttaa accagatgtg acttatgatg atgcagttga aaatatcgat
    13621 attggtgggc catctatgct tcgttcagca gcgaaaaatc atgccagtgt tacagttgtg
    13681 gtagatcctg ctgactacgc tgtggttttg gacgaattgg cagcaaacgg cgaaacctct
    13741 tatgaaactc gccaacgttt agcagccaaa gtatttcgtc acacagcggc ttatgacgcc
    13801 ttgattgcag aatacttcac agctcaagtg ggtgaaaaca agcctgaaaa actcactttg
    13861 acttatgacc tcaagcaacc aatgcgttac ggtgagaatc ctcaacaaga cgcggacttt
    13921 taccagaaag ctttgcctac agactactcc attgcttcag ccaaacagct caacgggaaa
    13981 gaattgtcat ttaataatat ccgtgatgca gatgctgcta tccgtatcat ccgtgacttc
    14041 aaagatagtc caaccgttgt ggctctcaaa cacatgaatc catgtggaat tggtcaagct
    14101 gatgacatcg agactgcttg ggactacgct tatgagtctg acccagtgtc tatctttggt
    14161 gggattgtcg tcctcaaccg tgaggtggat gctgcgacag ctgagaagat gcacggcgtt
    14221 ttcctcgaaa tcatcattgc accaagctat acggatgaag cgctagccat tttgatcaat
    14281 aaaaagaaaa acttgcgtat ccttgccttg ccatttaatg ctcaagaggc tagcgaagtg
    14341 gaagcagaat acacaggtgt agtcggtgga cttctcgtgc aaaatcaaga cgtggtcaag
    14401 gaaagcccag ctgactggca agtggtgact aaacgtcagc caactgagac agaagcgact
    14461 gctcttgagt tcgcttggaa ggctatcaag tacgtcaaat caaatggtat tatcgtgacc
    14521 aacgaccaca tgacacttgg tgttggtcca ggtcaaacca accgtgtggc ttctgttcgc
    14581 cttgccattg accaagccaa agatcgtctg gacggggcgg tccttgcttc agatgccttc
    14641 ttcccatttg cggataacgt ggaagaaatc gccaaagcag gaattaaggc catcatccag
    14701 cctggtggct ctgtccgtga ccaagaatcc atcgaagcag cggataaata cggcttgact
    14761 atggtcttta caggtgtgag acattttaga cattaagaag ataaaaggga agaaaacagt
    14821 ttctttcctt ttttggctta aaatgctaac tgaaacaaga ttaaaacgaa cttttttgat
    14881 ataatgttgg taaataattc gcaaaagagg ttgaggaatg aaactgcttg ttgtcggttc
    14941 tggtggtcgt gagcatgcga ttgctaaaaa gttacttgaa tcaaaagacg tggaaaaagt
    15001 ctttgtagct cctgggaatg atgggatgac tctggatggt ttggaattgg taaatatctc
    15061 tatttccgaa cattctaaat tgattgactt cgcaaagacc aatgatgttg cttggacctt
    15121 tatcggtcca gatgatgccc ttgctgctgg tatcgtggat gattttaacc aagctgggct
    15181 taaggccttt ggtccgacta gggctgcagc ggagctggag tggtccaagg attttgccaa
    15241 ggaaatcatg gtcaaatatg gtgtttcgac agcagcctat ggcacatttt cagatttcga
    15301 ggaagcaaag gcctatatcg aaaagcatgg tgcgcctatc gtagtcaagg cggatggctt
    15361 ggcgcttggg aagggtgtcg tcgtttctga gacggttgag caagcggtcg aagccgctca
    15421 tgagatgctt ttggacaata aatttggtga ctcaggtgcg cgcgtggtta ttgaggaatt
    15481 ctttgaagga gaggaatttt cactctttgc ctttgtcaat ggtgataagt tctacatcat
    15541 gccaacggct caggaccaca aacgtgccta tgatggcgac aaagggccta acacgggtgg
    15601 tatgggtgcc tatgcgccag ttccacactt accacagagt gtagttgata cagcggttga
    15661 caccattgtc aagccagttc tagaagggat gattaaagaa ggtcgccctt atctgggagt
    15721 tctttacgca gggcttatcc tgacagctga tggaccgaaa gtcattgagt tcaacgctcg
    15781 gttcggagat ccagaaactc agattatctt gcctcgctta acctctgact ttgctcaaaa
    15841 tatcacagat atcctggata gcaaggagcc aaatatcacg tggacggaca agggtgtgac
    15901 tctgggtgtg gttgtcgcat ccaagggcta cccgctaaat tattcaaagg gtgttgagtt
    15961 gccagtcaaa accgatggcg acatcattac ctactatgca ggggctaagt ttgcggaaaa
    16021 tagcagagca ctgctctcaa acggcggacg agtttatatg ctcgttacca cagcagatac
    16081 cgtcaaagaa gcccaagcca gcatctacca agaactatcc caacaaaaaa tagaaggact
    16141 cttctaccga acagatatcg gaagcaaggc aattaagtaa agatataaga ataacgcgcc
    16201 gtagtcgcca aacacgataa tggtcgtcgt ggtgaaaaga ccagaacagt gaatgttctg
    16261 gtcaggggga aacttggaga ccgtaggctc aaagtttagg aatgaaaccg aaggtttgct
    16321 tccgcctcca tcacctaaga ccattatcaa aaagaaaaat aaaaattcac aaaatacgtt
    16381 aatgatcgta tggtttgcga gcgttagcga gctaatatag aacaatcacc gccgttgtga
    16441 aagaacgatt ggatgataat ccaatcgttc agggaaattg gaagaccttg ggtttccaat
    16501 ttaggcatga gacacctttg gtggctgctg ccgtccctca caagctaagg tgattgttga
    16561 aaaagaggaa aaaggagaag aaatgaaacc agtaatttcc atcatcatgg gctcaaaatc
    16621 cgactgggca accatgcaaa aaacagcaga agtcctagac cgcttcggtg tagcctacga
    16681 aaagaaagtt gtttccgcac accgcacacc agacctcatg ttcaaacatg cagaagaagc
    16741 ccgtagtcgt ggcatcaaga tcatcatcgc aggtgctggt ggcgcagcgc atttgccagg
    16801 catggtagct gccaaaacaa cccttccagt cattggtgtg ccagtcaagt ctcgtgctct
    16861 tagtggagtg gattcactct attctatcgt tcagatgccg ggtggggtgc ctgttgcgac
    16921 catggctatc ggtgaagctg gagcgactaa cgcagctctc tttgccctcc gtctcctctc
    16981 tgtagaagat aagtccattg cggatgcact tgccaacttt gctgaagaac aaggaaaaat
    17041 cgcagaggag tcgtcaaatg agctcatcta aaacaatcgg aattatcggt ggcggtcaac
    17101 tgggtcagat gatggccatt tctgctatct acatgggcca caaggttatc gcgctggatc
    17161 ctgcggcgga ttgcccggcc tctcgcgtgg cggaaatcat tgtggcacct tataacgatg
    17221 tggacgccct ccgtcagttg gcagaccgtt gcgatgtcct cacttatgag tttgaaaatg
    17281 tcgacgctga cggtttggat gccgttatca aggatggaca actccctcaa ggaacagatc
    17341 tgctccgcat ttcgcaaaat cgtatttttg aaaaggactt tttgtcaaac aaggctcaag
    17401 tcactgtggc accctacaag gtcgtgactt ctagcctaga cttggcagat atcgacttgt
    17461 cgaaaaacta tgtcctcaag actgcgactg gtggctacga tggtcatgga caaaaggtta
    17521 ttcgttcaga agcagacttg gaagcagcct atgcgctagc agactcagca gactgcgtct
    17581 tggaagaatt tgtcaacttt gaccttgaga tttctgtcat cgtgtcagga aatggcaagg
    17641 aggtgacgtt tttcccagtt caggaaaata tccaccgcaa caatatcctg tctaagacca
    17701 tcgtaccagc ccgcatttct gaaagtctag cagacaaggc taaagctatg gcagtgcgaa
    17761 tcgcagaaca actcaacttg tctggaactc tctgtgtgga aatgtttgcg actgatgatg
    17821 acgttattgt caatgaaatc gccccacgac cacataactc tgggcactat tctattgaag
    17881 cctgtgattt ctctcagttt gacacccata ttctgggtgt tctcggagca ccattaccag
    17941 tcatcaaact ccatgcgcca gccgttatgc ttaatgtcct cggtcagcat gtcgaggctg
    18001 ctgagcaata tgtgacagaa aattcaagcg cccacctcca catgtatggt aaaatagaag
    18061 cgaagcacaa ccgcaagatg ggacatgtga ccttgtttag tgatgtaccg gatagtgtgg
    18121 atgagcttgg ggaagggatt gatttttagg acaagtctat gatacaaatt atcgttaata
    18181 catttattga aaaggataag actggagcag ttgttgaagt gttgtatgcc agtgctgacc
    18241 aagataaggt acaagctaaa tatgaagaac tagctgcaca ataccccgaa aattatttag
    18301 ctatctatga tgtaccgctg gatacggatt tgaatacact agatcattac ccgtctgtgt
    18361 ttattgaaaa agaggagttt gagtagaaat cttggtttac ctagatagct tattcccaac
    18421 agcttaagaa gaaaggaaaa attaacacat gatcaaccgt tactctcgcc ctgagatggc
    18481 gaatatttgg agtgaagaaa ataaataccg tgcttggctt gaggtggaaa tcctctctga
    18541 cgaggcatgg gctgagttgg gggaaatccc taaggaagat gtggctttga ttcgcaagaa
    18601 ggcggacttt gacatcgacc gtattttgga aattgagcag gagacgcgcc acgatgtggt
    18661 ggctttcacg cgtgcggttt ctgagactct tggtgaagag cgcaagtggg ttcactatgg
    18721 gttaacttct accgacgtgg tggatactgc ttatggttac ctctacaagc aggccaacga
    18781 catcatccgt cgtgaccttg aaaacttcac taatatcatc gctgacaagg ccaaggagca
    18841 caagttcacc atcatgatgg ggcgtactca tggtgtgcac gctgagccga caacctttgg
    18901 tcttaaattg gcaacttggt acagcgaaat gaaacgcaat atcgagcgtt tcgagcatgc
    18961 agctgctggt gtagaagctg gtaagatttc tggtgcggtt gggaactttg ccaatatccc
    19021 accatttgta gaggagtatg tctgcgataa acttggcatc cgtgcccaag aaatctctac
    19081 acaagtcctt cctcgtgacc ttcacgctga gtactttgcg gttcttgcca gcattgcgac
    19141 ttcaatcgaa cgtatggcga ctgagattcg tggtctacaa aaatctgagc aacgcgaagt
    19201 agaagagttc tttgctaaag ggcaaaaagg gtcttcagca atgcctcaca aacgcaaccc
    19261 aatcggttct gaaaatatga ctggtctggc gcgtgtcatt cgtggtcaca tgattacggc
    19321 ttatgaaaac gtcgctctct ggcacgaacg cgatatttct cactcatcag ctgagcgtat
    19381 catcacacca gatacgacca ttttgattga ctacatgctc aaccgttttg gaaatatcgt
    19441 caagaacttg acagtcttcc cagaaaatat gatccgaaac atgaactcga cttttggtct
    19501 tatctttagc caacgggcta tgttgacatt gattgaaaaa ggcatgaccc gtgagcaagc
    19561 ctatgacttg gtgcaaccaa aaacagccta ctcttgggac aaccaagtag actttaaacc
    19621 acttcttgag gcagattcag aagtaacatc acgtctcact caagaagaaa tcgatgaaat
    19681 cttcaaccca gtttattaca ccaaacgagt ggatgatatc tttgaacgtc ttggactagg
    19741 tgattaatta aaaaataaac agcgagcttc aatctcgctg tttatttttt atcgaaaaga
    19801 cttagtcttc ttttctttta gtgagtccat aggctgctag tgtggccatg agtcctgcga
    19861 ctactagtcc tgcagaatcg tgagttcctg tttcaggaag ttttttctct attaccacag
    19921 gagctggatc ttgaggaaga gctttgcttt cctcagcagg agcagttgat ggagctggtt
    19981 ggcttgggat ttctagtttt ggtttttctt cagcaatagc ggcttgtccg ttttcatcgc
    20041 ctacatgtgt taccatagtt ccgacttcga ctatttgagt aacggcttcc tgtgctacga
    20101 cactatttac aagtgttttc acttccttac catcggcaga agtgctcaca gagtagaagt
    20161 tgctacgatg tccattgacg cccttagtaa tgacttgtgt ttttcctttg agtaagagtg
    20221 gattttcacg agtcactgtg gtaaatggaa tttcttcttt ttggatatcc agtctaggtt
    20281 ttacctcagt agttggtgca agaccacttt catcaccctt gtgagttaca ggagcgccaa
    20341 cttcaaccac ttggtttata acttctttgg ttacctggct atcaaggact gtttctgttg
    20401 tttttccatt ttcagtgagt acagagatgt aatgagttcg ctcacctttg actcctgctg
    20461 tgataatatt ttcctgacca gctgggaggt taggattttc tttcttgata acttcaaatg
    20521 gaatttcttc agttcttgtg atgagttctg gtctggtttc aacattggca gccacttcat
    20581 tttcatccag gcttcctgaa tgagttgcag ctggtttgag gccttgaaga gcggctttta
    20641 ggttggctac aagtgtgtca agctcagctt gtttattacg gttgaggttg taatttagag
    20701 ctgttttagc tgcgtcaagg gcctcaagac tttctttact atatccttct aagtttgtag
    20761 gaattttagc taattcttcg cggagagcat tataattagc acggaagtag tctttgttgt
    20821 ggtctgcaaa ggcagtcatg agttcaaaga tttcctcttc cttgtattca gcgcttggtc
    20881 tatctgccca gattgaaagc atacttccga ctgttggaag atctacttca ggatatttgg
    20941 tagaagctag ttgattgaat ggtgtttttc cagtattctc aatagctttc ttgaggaaac
    21001 caccaccatc ttctggtttt tgaccaagaa tgtagtacca gtcaccgttg gtattcaaga
    21061 atttatagcc tttgcttgct aggtattgag gtgatgcgag gttatatccc caccagcctt
    21121 tagaccagta agaaatcaag acatctttgt caaactgaac atcgtccttg tcttcatagt
    21181 agaagccatc gttgaaggcc attggttgaa gccctctttc tttggccata gctgcgaggg
    21241 tgttggcata ttcggcaaat ttgccataga gttgatacca cttgaggtag taccagcctt
    21301 gggcactagt cgcatcgttg gcgtattcgt cagtaccaaa gttgaaaatc tttgttttac
    21361 ctgcaaagaa gtccatgtat ttaccgatga gggcttttac aaagttcatc gcttcttcgt
    21421 ttttcaagtc catagttgtt tttgaaactt tatcaaagtg ggcttgagga tttttaatac
    21481 ctaatttttc catggcaacc agcatagcat ccatgtgacc tggactgtta atagctggga
    21541 tgagaccgat gtccttagat ttagcgtatt caattagctc tgttacttct gcctgtgtta
    21601 gtgcagtacc gtttggatcg tcgtagtaag ctttagttcc ttcgataata gcttttttaa
    21661 cgtcatcact agcataggtt tttccgttgg cagtaatggt catatcatcg agtagaaagc
    21721 gaagtccgtc atttcctaga aggagatgga catcagaata tccgagctca ctggccttgt
    21781 ctacgatgcg tttgagctgg ttcagagtaa agtatttgcg tccagcatcg attgagatta
    21841 ccttgttttt ggcaagtttt tcaacctcac gtttagcttc ttcttctttt tgagcttcag
    21901 gcgtgagggt caagttgttg acagtttctt gaagtttagc aatggcttga tcaatcgtat
    21961 cttgttgggc acggctaagg ttgctatcga gagagcgaat agctttttca gcttctttta
    22021 cggccgcgac gctttctgca gtataacggt tcaggtcttt tggtacctcg ttaagtgttt
    22081 gctctgcaga ttcataatca gctgcgaagt attcagcgtt ggcatttgca aaatgacgca
    22141 tgagtttgaa gaggcgtgat ggtgaataac gtgcagatgg agtgtcagcc caagcagcta
    22201 ccatactacc gatgattggg atatcagctc cttctgtttt tggtacagaa gtgattggtg
    22261 tgtttttaat accattgagc ccctgatcga gattgtacca gccttggcca tcagcgtttc
    22321 gtccaagaac gtagtaccaa gcatcattgg tattaaggat ttggtgacct ttttcagcta
    22381 gtagtttaga agaagcgaca tcgtagcctc cccaaccacc agtccacata gaaacgatga
    22441 tgtctttgtc aaaactacca aagcttgtgt cgctattgta gtagataccg tcgttaaagg
    22501 ccattggttt gagaccgtgc gattttacaa tacgagcgag gtcattggcg taggcaataa
    22561 atttttcata gccttttaca gggtagcctt cgtttggata gtatttatca gcttgaagca
    22621 cactccaacc tttagcatct gtcgcatcat tggcatattc atcaagtccg atgttgaaga
    22681 tttcagtctt tttcgcgaaa taagcagcat acttgtcgat aagggctttt gtaaaagcga
    22741 cagcttgttc gttgtcaaga ttgacagtac gggctgattc cttcccaaaa tagctaaagt
    22801 tagggttttg gattcccaat tctttcatgg cattgagaat cgcatccatg tgaccaggac
    22861 tatttactgt cggaatgaga ccgatacctt tatctttggc atagttaatc agatctgtca
    22921 tttgactttc tgttaagtga ttgccgtttg gatcgttgta ataatcattt gtaccttttt
    22981 caatggcgcg tttgacatcg tcactggcat aggtcttgcc gttagctgtg atgctcatat
    23041 cgtccaacat gaaacggagt ccatcatttc cgactaatag gtgtaaatca gtgtagccat
    23101 aatgtttcgc tttatcgatg atttccttga gctgttctgg tgagaaatat ttacgtccag
    23161 catcaataga aacaattttc tttttcgcta gtttttcatt tacagttgca gcacgttcct
    23221 ttcctgcctc tgtttccggt ttgtcatcct ctgctttcgc ttcatctttt ttagctggtt
    23281 tatccttgtc agtcttgtct gtatttgact ctttagaatc aacctctttc gcttcttcct
    23341 ttttagggct agcttcttct gcctttttat tagcagtttc tttttcagca gaagttggag
    23401 ttaccacttc tgctttatca ctaggagttg aactaacttc ctcttgtggt ttttcttctg
    23461 tttttggaag actagctacc ttatcagtag ctggagtttc tgtttctaca gtttttggag
    23521 cttctggttg aagctctgct ttaggtgttt cctcagtccg attttcggat gattgagggg
    23581 aatcagaaac cgtatggatg gtcggttggt tttctgtagt agtaggagta actccatcgg
    23641 ctgcaacagt ctgtgcttgg aaggcaaatc caattagaac agaagctgct cctacagcgt
    23701 atttacgaat agaaaaacgc tgttgttttt catgtttcat tgcaaaacct cctgattgca
    23761 ttgttatatt gatagcgatt atataaatca acgcctttat tttatttctt atattaacga
    23821 gagtcaagag gagatgacaa aaaactataa taagtataaa aaaatataaa atttaaactt
    23881 aagatttcag attggtcgga aaaaatacgt atatatatct agtataattt ttggttctat
    23941 ttctataaaa tattccacaa attatagaat tttccaaaaa taggtaagcg ctaccttttt
    24001 ggtgtggtat aataagcata gaaaaagccc aagcgattag ctcaggcttt cttcttagtg
    24061 atcacggtca catgagataa atttaatctt gtagtaatca gatcgtttgt aagtttcact
    24121 gtattctaaa acttggccag ttgattcgag tttggtgatt ttagtttgta ggacagtagg
    24181 gaattgttca tcgactccga ggactgaagc cgcatgttct ggagttggaa agactatttc
    24241 gttgatttct tcaaagtgtt catcattcat gtgaatgtgg tagtctaact tgaaacgatt
    24301 atagatagaa ctatagtatt caaggtttgg ataatttgcg ttgatatatt gttctgggat
    24361 gtaggatgta tggtagatat aaacgacacc gtttgattcg cggatacgtt caatcttgta
    24421 gtagaattga tcgccgcgta gacccaattt ttccaagtaa acaagcttgt ttccgcgttc
    24481 aattgaaaga acagttacct tatcatcttt agcattgaag agttcaatat ctgaaaactc
    24541 tacaagcttg tgtttgcgtg cacgtgaaac gaaggttcct tttccttgtt ggcggacaat
    24601 atagccatct ttggcaaggt cgtttaaggc gcgaacaact gtgatagagc tgacatcgta
    24661 cattgaaatg agttctgctt cagtgtaaaa tttatctcca ctgctaaact gcccagagat
    24721 gattttattt tttaattcgt cttttatgta ttgatatttg ggaattgcca tatttttacc
    24781 tctattttcc ttctccatag gaaattttac cataaaagcg aaaaaaatag tagtcttttg
    24841 aataaaaaat tagaataata gtttgaaaaa ttaagcgata tagggattgc tcatatttta
    24901 tcaatgtatt ctatacaaaa ttattttagg tcccatattc cgaatttaaa gagcgtttga
    24961 aatgggtcta aaaatgtttg aaactaattg aatgtgtgta taatagtaaa aatgcagtaa
    25021 atatcccgac aatttctatt gacaattcaa acagattggt ttataattaa tataacaaca
    25081 aatgaaagcg caaactttcg cggtcggaag gtagttttat gacacgattt gagatacgag
    25141 atgatttcta tctcgatgga aaatcattta agattttatc tggtgccatt cattatttta
    25201 gggttcctcc agaggattgg tatcattcgc tctataactt gaaggctctt ggttttaata
    25261 cggtagagac ttatgttgct tggaatttac acgagcctcg tgaaggtgag tttcattttg
    25321 aaggtgatct ggatttagag aaatttctcc aaatagcgca ggatttgggt ctctacgcaa
    25381 ttgtgcgtcc gtctccattt atctgtgcgg aatgggaatt cggtggctta ccagcttggc
    25441 tcttgaccaa gaacatgcga attcgctcat ccgacccagt atatatcgag gcagttggtc
    25501 gctactatga tcagttattg ccaagactgg tgcctcgttt gttggacaat ggtggcaata
    25561 ttctcatgat gcaggttgaa aatgagtatg gttcttacgg agaagataag gcttacctga
    25621 gagcgattcg acagctaatg gaagagtgtg gcgtaacctg tcccctcttt acatcagatg
    25681 gtccatggcg agctactctg aaagctggaa ccttaattga agaggacctc tttgtaacag
    25741 gaaactttgg ttctaaggca ccttacaact tttcgcagat gcaggaattc tttgatgaac
    25801 atggtaagaa atggccactc atgtgtatgg agttctggga tggttggttc aatcgctgga
    25861 aagaaccgat tatcacacgg gatcctaagg aattggcaga tgcagttcga gaggttttgg
    25921 aacaaggctc tatcaatctt tacatgttcc acggtggtac aaactttggt ttcatgaatg
    25981 gttgctcagc tcgaggaact ttggacctgc cacaagttac gtcttatgat tacgatgccc
    26041 ttctggatga agaaggaaat ccaactgcta aatatcttgc agtcaagaag atgatggcaa
    26101 cacatttttc agagtatccg cagttggaac cactctacaa agagagtatg gagttggatg
    26161 ctattccact agttgaaaaa gtttctttgt ttgaaacctt agatagcttg tcaagtcctg
    26221 tagaaagtct ctatcctcaa aagatggagg agctgggaca aagttatggc tacctacttt
    26281 atcgaacaga aacaaactgg gatgcagaag aagaaagact tcgtatcatt gatggtcgag
    26341 atagggccca gctgtatgtc gatggtcagt gggttaaaac tcaatatcag acagagattg
    26401 gggaagatat tttttatcaa ggtaaaaaga aagggctatc taggttagat atcttgatag
    26461 aaaatatggg gcgtgtcaac tatgggcata agttcttagc ggatacgcaa cgtaagggaa
    26521 ttcggacagg ggtctgtaag gatctgcatt tcttactaaa ctggaaacac tatccactcc
    26581 cactagacaa tcctgagaaa attgattttt caaaaggatg gactcaagga caaccagcct
    26641 tttacgctta tgactttaca gtcgaagagc caaaagatac ttacctagac ttgtctgagt
    26701 ttggtaaggg ggttgccttt gtcaatgggc agaatctagg acgtttttgg aacgttggcc
    26761 caactctctc actttatatc cctcatagct atctcaagga aggtgccaac cgcatcatta
    26821 tctttgaaac agaaggtcaa tataaagaag agattcattt aactcgtaaa cctacactaa
    26881 aacatataaa gggggaaaac ttatgacaat tgtaggatgc cgtattgatg gacgtttgat
    26941 ccacggacaa gtagccaatc tttgggctgg aaaactaaat gtttcacgca ttatggttgt
    27001 agacgacgaa gttgtcaaca acgatattga aaagagtggt ttgaaacttg cgacaccacc
    27061 aggtgtgaaa ttgagtattt tgccagttga gaaagctgca gccaatattc ttgctggtaa
    27121 atacgatagc caacgtctct ttatcgtggc tcgtaaacca gaccgcttcc ttggtttggt
    27181 agaagcaggt gtaccacttg aaacccttaa tgttgggaat atgtctcaaa caccagaaac
    27241 acgttctatt acacgttcta tcaacgtagt agacaaggat gtggaagact tccacaaact
    27301 ggcagaaaaa ggtgttaaac ttactgctca gatggttcca aatgatccaa tttcagactt
    27361 tttgagctta ttaaaatagg aaaaaaattt ttaggaggtc attgttatga tacaatggtg
    27421 gcaaatttta cttctcactt tgtactcagc ttatcaaatc tgtgatgagt tgacgatcgt
    27481 ttcatctgca ggttctcctg tatttgctgg tttcattact ggtttaatca tgggagatgt
    27541 gactactggt ttacttatcg gtggtaactt gcaactgttc gttcttgggg ttggtacctt
    27601 cggtggtgct tctcgtatcg acgcaacttc tggtgcggtt cttgcgacag ccttctctgt
    27661 ttcacaagga attgatgcac cgcttgccat tactacaatc gctgtaccag tagcagctct
    27721 cttgacttac ttcgacgttc ttggtcgtat gactactacc ttcttcgctc accgtgtgga
    27781 tgctgcaatc gaacgctttg actataaagg tattgaacgc aactacttgc ttggtgcgat
    27841 tccgtgggct ctatctcgtg cccttccagt cttctttgcc cttgcttttg gtggtgcctt
    27901 tgtacaatca gtagtagact tcgttgaagc ctacaaatgg gttgcagatg gcttgacact
    27961 cgcaggacgt atgcttccag gtcttggatt tgcaatcttg cttcgttacc ttccagttaa
    28021 acgtaacctt cactaccttg ctatgggatt tggtttgaca gctatgttga ctgttcttta
    28081 ctcatatgta acaggtcttg gtggcgctgt tgctggtatc gtaggtactc ttcctgctga
    28141 agttgctgaa aaaattggtt tcgtgaacaa cttcaaaggt ttgtctatga ttggtatttc
    28201 tatcgtaggt attttccttg cagtgcttca cttcaaaaat agccaaaaag tagctgtagc
    28261 agcaccttct acaccatcag aaagtgggga aatcgaagat gacgaattct aattacaaac
    28321 ttacaaaaga agattttaat caaatcaaca aacgtagctt gtttactttc caattaggtt
    28381 ggaactacga acgtatgcaa gcttctggtt acctttacat gatcttgcct cagttgcgta
    28441 aaatgtatgg tgatggaact cctgaattga aagaaatgat gaaagttcat actcaattct
    28501 tcaatacttc accattcttc cataccatta tcgctggttt tgaccttgcc atggaagaaa
    28561 aagatggtgt aggttcaaaa gacgctgtta acggtatcaa gacaggtttg atgggaccat
    28621 tcgctcctct tggggataca atctttggtt cacttgtacc tgctatcatg gggtcagtcg
    28681 cagcaactat ggctatcgct ggccaacctt gggggatctt cctttggatt gcagttgcag
    28741 tagcgtatga catcttccgt tggaaacagt tggaatttgc ttacaaagaa ggggttaacc
    28801 ttatcaacaa catgcaaagt accttgacag ctttgattga cgctgcatct gtacttggtg
    28861 tcttcatgat gggtgctctt gtagcaacag tgattaactt tgaaatttct tacaagttgc
    28921 caatcggtga aaagatgatt gatttccaag acatcttgaa ccaaatcttc ccacgtttgc
    28981 ttccagcaat ctttactgcc tttatcttct ggttgcttgg taaaaaaggt atgaactcta
    29041 ctaaagctat cggtattatt atcgtacttg ctttggctct ttctgccctt ggtcactttg
    29101 cacttggaat gtaattcctt atgactaaat cattaatttt ggtgagccat ggtcgcttct
    29161 gtgaggagct tagaggtagc acagaaatga ttatgggccc acaagacaac atttacacag
    29221 tagctcttct tccagaagat ggcccagaag aatttactgc taaatttgaa gctgttattg
    29281 aaggattgga tgatttccta gtctttgcgg atcttctcgg tgggacacct tgtaatgtgg
    29341 tgagtcgctt gatcatggaa ggtcgtgata ttgaccttta cgcagggatg aatcttccaa
    29401 tggtgattga atttatcaat gcgagcctta caggcgcaga tgcggactac aagagccgtg
    29461 ctgcagaaag cattgtgaaa gttaatgacc tgttagcggg cttcgatgat gacgaagatg
    29521 aataatactc ttcgaaaatc tcttcaaact acgtcaacgt cgccttgccg taggtatatg
    29581 ttactgactt cgtcagtctt atccggcaac ctcaaaacgg tgttttgagc tgacttcgtc
    29641 agtcttatcc ggcaacctca aagcagtgct ttgagcagcc tgcggctagt ttcctacaga
    29701 ttttagttgg aactcgattc aattcatgtg acaacgtgaa aatcgttaga gcattttata
    29761 tagaatatac atgggaatgg agcttactcc cattcccata tttaatagaa aaagaggaac
    29821 tcaatgctac attatacaaa agaagacttg ctcgaattgg gtgcagaaat cactacgcgt
    29881 gaaatctacc aacagcctga tgtatggaga gaagcttttg aattttatca agcaaaacgt
    29941 gaagaaattg cagcctttct acaagaaatc gctgataaac atgactatat taaggttatc
    30001 ttgacaggtg ctgggacttc tgcttatgtg ggagatacct tgctacctta ctttaaggaa
    30061 gtctatgacg aacgcaaatg gaatttcaat gctattgcga caacagatat cgttgccaaa
    30121 ccagcaacct atttgaaaaa agatgtggca actgtccttg tgtcttttgc tcgtagtggg
    30181 aactcgcctg aaagtgtggc gactgttgat ttggccaaat ccttggtgga tgagctttat
    30241 caagtgacga ttacttgtgc agcagatggt aaattggctc ttcaagctca cggtgatgac
    30301 cgtaatctct tgctcttgca accagctgtc tctaatgatg ctggatttgc catgacttct
    30361 agctttacgt ctatgatgtt gacaactctc ttggtctttg atcctacaga atttgctgtt
    30421 aagtctgaac gttttgaagt tgtatctagt cttgcccgta aagttttaga caaggcagaa
    30481 gatgtcaaag agctcgttga tttagacttt aaccgtgtca tctatctagg cgctggtcct
    30541 ttctttggac ttgctcatga agctcagctc aagattttgg aattaactgc tggtcaagtt
    30601 gcgaccatgt atgaaagccc agttggcttc cgtcacggtc caaaatctct tatcaacgac
    30661 aatacagttg ttttggtctt tggtacaacg acggactaca ctcgtaagta cgacttggac
    30721 ttggttcgtg aagttgctgg tgaccagatt gctcgtcgtg ttgtgctttt gagtgatcaa
    30781 gcttttggtc ttgaaaatgt caaagaagtg gtccttggtt gtggcggtgt cttgaatgat
    30841 atttaccgtg tcttccctta catcgtttat gcccaactct ttgccctatt gacttcactc
    30901 aaggtagaaa ataaaccaga tacaccgtct cctacaggta cagtaaaccg tgtagtacaa
    30961 ggtgtcataa ttcacgaata tcaaaagtaa gacagtgttt atgaattctt gacaagagga
    31021 tttgtaaatt atcagataaa ccatagattg tcagtacgct ttctatggtt tgtttgcttg
    31081 agagaaatag taaaaggaga acagaatgaa agcatacaca gagcgtgtat ttggaaatgt
    31141 tgagggtgag gatgtcttgg cctatcgatt tgagacagac ggtggctacc aacttgaggt
    31201 tatgacttat ggtgcgacta tcttgcgcta tgtcgcacct gacaaggctg gaaattttgc
    31261 caatgttatc ttgggatttg atgactttga tagttatgta ggcaatagtc ccaagcatgg
    31321 agcaagtgta ggtcctgtag cgggtcgtat tgcaggtgcg acctttgagc tcaatggtaa
    31381 gacctatgac cttgaggtta ataatgctag caactgtaat cacagtggtt caactggttg
    31441 ggattccagc ttgtttgaag ttgaagaagt aagcgatcat ggcttgactc tctacacaga
    31501 gcgtacagat gggacaggag ggttccctgg aaatctcaag atttggatca gttatcactt
    31561 ggaagaaact ggtgcctatg aaatcagcta caaggtaacg accgatcagg atacgctggt
    31621 caatccaacc aaccacagct atttcaactt gtctggtgat ttcacgcaga cgattgaccg
    31681 tcatgtcttc caactaaaca cagagggcat ttactcaatc gctcctgacg gtgttcctgc
    31741 caaaactcca gaagccaacc gtgatgtggt caaacacatc tacaatggtg ccttgttgaa
    31801 ggatatcttt gcagaagaag atgagcaaat ccagctggca tcaggtttgg atcatccatt
    31861 tgcccttcct gcaggccatg acaatgctgg attcctttat gaccaaaatt caggtcgctt
    31921 cctgcttttc aagacagaag ctccttgctt tgtggtctac acagcaaact ttgtggatga
    31981 aagtgtcatc ataggaggtc agccaatgct acagcacaat gggattgctc ttgaagcgca
    32041 agctttacca gatgccattc acagtgacct taaaggccaa gtcattctta aagctggtca
    32101 aaccttcacc agtaagacac gttatgaact tgttgtgaaa taaaaaaagc tggtcaaaaa
    32161 gtctttaaaa ttaaaataac gcatattgtc aggtgatgaa aagtttgata atatgcgttt
    32221 tattatgaaa tgatttactt tatattatcc tgaaatggtg ttatttttga gttatctggc
    32281 ttgactttct tgatggaaat tatataatag ttgtaacaat gataattaca actagaaaag
    32341 aggaccattt atgacctatg aatacaagag tcacatttat ttggcagaga cagctttaaa
    32401 tgtaaaggat ttggccagtc aaacagcctt ttatcagcaa gttattggtt tagaaatctt
    32461 atctcaaact gagacagagt ccattctagg ccttggtgga aaagtcttgg tacagctgat
    32521 tcaagcacaa gagagcggag aagtgaggga atattatggt ctttaccatt tggccattct
    32581 cttgcccaca cgcaaggctt tagctgatgt cttgaaacac ctgacagatt tacaaattcc
    32641 tcttgtcggc ggtgcagacc atggttacag tgaagctatt tacttggaag atttggaggg
    32701 aaatggcatt gaactctatc gagataagcc agtttccaca tgggatattc gagaagatgg
    32761 acgcattatc ggagtgacag aggctcttgc ggcgcaggac atttatgagt tgggggaaag
    32821 agtagagccc tttatcctgg cagaaggtac gagaatgggg catattcatc tttccgtcaa
    32881 ggatagtcga aagtccagcc agttttatca aaaggtgtta gggctagagg ataaattcag
    32941 tgtgcctagc gctagttgga ttgcggctgg agattaccat catcatttag cagttaacga
    33001 atggggagga aaaggtctgg cttcgcgtaa gcaaggctta ccaggtttag cctactatgt
    33061 catcgaagtc gcacacaaaa aagaactatt aacgattgcc caacgagcac aagaagttga
    33121 cgcaccaatc aaatggatga catcgagcca attggaaatc acagactcag atggcatcgt
    33181 gacccgtatt cgtttagcaa ggtaaaatta ggaattttta ataagttata agtattgcta
    33241 gtttgctttt tgaacggtct ttggtaacag aactgcgtga gctggatggg cgagaatttt
    33301 gacaaagaag ctgattagag atataatgaa gaaaaatcga gcaaggaaaa agaaatgaca
    33361 aattcaaagt atattacttg tttgaaacgt tcagagggcc agttgtgtgg gattcaaaag
    33421 atgattgaag gagatcgtga ctgtgctgat attgtgacgc aactgacagc agtgagatct
    33481 agtgtagagc gcgtgattga gatgataatt accgaaaatc ttactgaatg tatcaatcag
    33541 ccactagatg attctgaagc tcaaaaggaa cgcttagaaa aggctatccg atacttgatt
    33601 aaacggaaat aaatgaatgt tttgagacga tatgtgcaaa ggtctattaa ctattagaat
    33661 agtttaatgg gagtcaaaag aagttgtaaa aaatctttaa aattaaaaaa acgcatagta
    33721 tcaggtattg aaatgtactg accccaaaaa gttagatttt ttctgtctaa cttttggggt
    33781 gcagttcata agaaccttgg taatatgcgt tttattatgg ggagatttat acttttcgaa
    33841 aatctcttca aaccaggtca gcttcacctt gccgtagata tggttactga cttcgtcagt
    33901 tctatccaca acctcaaaac agtgttttga gctgacttcg tcagttccat ccacaacctt
    33961 aaaacagtgt tttgagctga cttcgtcagt tccatccaca accttaaaac agtgttttga
    34021 gcagcctgcg gctaacttcc tagtttgcac tttaattttc attgagtatt acttcatctt
    34081 ctcatgaaat tgagtttttg cccagttcct cttgattatt ctacttgacc aggccaagca
    34141 ttcataccac cttctacgtt ggtaacggtg aggccttggg agatgagaaa ttggcaggta
    34201 gatgcagagc ggactcctcc ttgacaaata acatagtatt catggtcagg tttgagttct
    34261 ttgtagcctt gctctaaggt acttaatgga agatttttgg cacctggtgc atgtcctgct
    34321 tggaattcat gtgcttcacg gacatcgata agttctagat tttcattttg gtattttcca
    34381 taaaagtcag ccatgctgat actagtttcc atattctact ccttctgggt taaccatttt
    34441 gtatagtgaa taagcgccgt caaggttttg ggcggtaaat cctgcttgct tgaggatagg
    34501 ctctgcgata tagctgcgca aaccactgtg gcagctgacg atgtaggctt gttttttgtc
    34561 cagttcatca gcttcctcct tgacactttg tcagtttttg atacaatagt acaaaattag
    34621 aggaggtggg ctatgattca gaaacatgcg attcctattt tagagtttga tgacaatcct
    34681 caggcggtta tcatgcccaa tcacgagggg ctggacttgc agttgccaaa gaagtgtgtt
    34741 tatgcatttt tagatgagga gattgaccgc tatgcaaggg aagtaggggc ggattgtgtc
    34801 ggcgaattcg tttctgctac caagacctat ccagtctatg tcatcaacta caagggtgag
    34861 gaggtctgtc tggctcaggc tcctgttggc tccgctccag cagcccagtt tatggattgg
    34921 ttgattggct atggtgtgga gcagattatc tctactggga cctgtggtgt tctagctgat
    34981 atagaggaaa atgcctttct agtccctgtt cgcgctctgc gagatgaagg agccagttac
    35041 cactatgtgg caccttctcg ttatatggaa atgcagccag aggctattgc tgctattgag
    35101 gaagttttgg aagacagagg gattccttat gaagaagtca tgacctggac gacagacggt
    35161 ttttaccgag aaacggctga aaaggtggct tatcgtaagg aagaaggctg tgctgttgtg
    35221 gagatggagt gttctgctct tgcggcagta gctcaattgc gtggggttct ctggggtgaa
    35281 ttgttgttca cagcagattc tctagcggac ttggaccagt acgacagtcg tgactggggc
    35341 tcggaagctt ttaataaggc gctagaactg agtttagcaa gtgttcacca cctttagttg
    35401 tactggcaaa ggatttgttt tatcataaaa tgtctagctc atacttttca aaaatatgtt
    35461 taaacgaggt caccttcctc ttgtcctaag catgttgagg ttgggaaaaa tctttaaaat
    35521 cagaaaaacg tatcatatca ggtgatgaaa accttgatac tatgcgtttt atgttggtaa
    35581 gatttagagt gagatgaaat gatactcttc gaaaatcttt tcaaaccagg tcagcttcac
    35641 cttgccgtag gtatatgtta ctgacttcgt cagtcttatc cggcaacctc aaaacggtgt
    35701 tttgagctga cttcgtcagt tctatttgca acctcaaaac agtgttttga gcaatctgtg
    35761 actagctttc taatcgatgc cttggttctc attgcctata atcaaaaaga gaaattttct
    35821 cctgaaaagc atatagagta gctggcgtta aaagctcctg tcttgctttt ttgacctata
    35881 gtcacatcta tcaagtattg ttcttgccta agctatcaat aaaaaggtgg cattttttag
    35941 gcttggtgtt agtagatttt gccttatcct atctaagtca tttcgaactt tttatggtac
    36001 aatggaaaca tgttattcaa attatctaag gaaaaaatag agctaggctt atctcgttta
    36061 tcgccagccc gtcgtatttt tttgagtttt gccttggtca ttttactagg ctctcttctt
    36121 ttgagcttgc cctttgtcca agttgaaagc tcacgagcga cttattttga tcatcttttc
    36181 actgctgtct ctgcagtctg tgtgacaggt ctctcaaccc ttccagtagc tcacacctat
    36241 aatatatggg gccaaataat ctgtttgctc ttgattcaga tcggtggtct agggctcatg
    36301 acctttattg gggttttcta tatccagagc aagcaaaagc ttagtcttcg tagccgtgca
    36361 actattcagg atagttttag ttatggagaa actcgatctt tgagaaagtt tgtctattct
    36421 atttttctca cgaccttttt ggttgagagc ttgggagcta ttttgcttag ttttcgcctt
    36481 attcctcaac ttggctgggg acgtggtctt tttagttcca tttttctagc gatctcagcc
    36541 ttctgtaatg ccggttttga taatttaggg agcaccagtt tatttgcttt tcagaccgat
    36601 ttactggtca atctggtgat tgcaggcttg attattacag gcggccttgg ttttatggtc
    36661 tggtttgatt tggctggtca tgtaggaaga aagaaaaaag gacgtctgca ctttcatacg
    36721 aagcttgtac tattgttgac tataggtttg ttgttatttg gaacggcaac tactctcttt
    36781 cttgagtgga acaatgctgg aacgattggc aatctccctg ttgccgataa ggttttagtt
    36841 agcttttttc aaacagtgac gatgcgaaca gctggctttt ctacgataga ttatactcag
    36901 gctcatcctg tgactctttt gatttatatc ttacagatgt ttctaggtgg ggcacctgga
    36961 ggaacagctg ggggactcaa gattacgaca ttttttgtcc tcttggtctt tgcacgaagt
    37021 gagcttctag gcttgcctca tgccaatgtt gcgagacgaa cgattgcgcc gcgaacggtt
    37081 caaaaatcct ttagtgtctt tattatcttt ttgatgagct tcttgatagg attgattctg
    37141 ctagggataa cagccaaagg caatcctccc tttatccacc tcatatttga aaccatttca
    37201 gctcttagta cagttggtgt aacggcaaat ctgactcctg accttgggaa attggctctc
    37261 agtgttatca tgccacttat gtttatggga cgaattggtc ccttgacctt gtttgttagc
    37321 ttggcagatt accatccaga aaagaaagat atgattcact atatgaaagc agatattagt
    37381 attggttaag aaaggaaaga gcatgtcaga tcgtacgatt ggaattttgg gcttgggaat
    37441 ttttgggagc agtgtcctag ctgccctagc caagcaggat atgaatatta tcgctattga
    37501 tgaccacgca gagcgcatca atcagtttga gccagttttg gcgcgtggag tgattggtga
    37561 catcacagat gaagaattat tgagatcagc agggattgat acctgcgata ccgttgtagt
    37621 cgcgacaggt gaaaatctgg agtcgagtgt gcttgcggtt atgcactgta agagtttggg
    37681 ggtaccgact gttattgcta aggtcaaaag tcagaccgct aagaaagtgc tagaaaagat
    37741 tggagctgac tcggttatct cgccagagta tgaaatgggg cagtctctag cacagaccat
    37801 tcttttccat aatagtgttg atgtctttca gttggataaa aatgtgtcta tcgtggagat
    37861 gaaaattcct cagtcttggg caggtcaaag tctgagtaaa ttagacctcc gtggcaaata
    37921 caatctgaat attttgggtt tccgagagca ggaaaattcc ccattggatg ttgaatttgg
    37981 accagatgac ctcttgaaag cagataccta tattttggca gtcatcaaca accagtattt
    38041 ggatacccta gtagcattga attcgtaaag agggatgacc cctctttttt gatgcccaag
    38101 atggcaaata gagacagaag ccccttgtct tctagtaaaa gttcttcaaa ggctggactt
    38161 tatggtaaaa tagaaggaag tgacaagaga gagtaatact caatgaaaat caaagatcaa
    38221 actaggaaac tagctgcggg ctgctcaaaa cactgttttg aggttgtgga tagaactgac
    38281 gaagtcagct caaaacactg ttttgaggtt gcagatagaa ctgacgaagt cagtaacatc
    38341 tatacggcaa ggcgacgttg acgcggtttg aagagatttt cgaagagtat aagaaaaaat
    38401 cagtccccta aaggagcaga ttatgaagtt attgtctatc gccatttcta gctataatgc
    38461 agcagcctat cttcattact gtgtggagtc gctagtgatt ggtggtgagc aagttgggat
    38521 tttgattatc aatgacgggt ctcaggatca gactcaggaa atcgctgagt gtttagctag
    38581 caagtatcct aatatcgtta gagccatcta tcaggaaaat aaatgccatg gcggtgcggt
    38641 caatcgtggc ttggcagagg cttctgggcg ctattttaaa gtagttgaca gtgatgactg
    38701 ggtggatcct cgtgcctact tgaaaattct tgaaaccttg caggaacttg agagcaaggg
    38761 tcaagaggtg gatgcctttg tgaccaattt tgtctatgaa aaggaaggtc agtctcgtaa
    38821 gaagagtatg agttacgagt cagtcttgcc tgttcggcag atttttgact aggaccaggt
    38881 cggaaatttc tccaaaggcc agtatatcat gatacactcg ctgatttatc ggacagattt
    38941 gttgcgtgct agccagttct aactgcctga acatactttt tatgtcgatg atctctttgt
    39001 ctttacgccc cttcagcagg tcaagaccat gtactatctg cctgtcgatt tctatcgtta
    39061 tttgattggg cgtgaggacc agtctgtcaa tgagcaagtg atgattaagc gcattgacca
    39121 gcaactcaag gtcaatcgac tcttggtaga ccagcttgat ttgtcccaag tgagtcatcc
    39181 taaaatgcga gaatatctgc tgaatcatat tgaaatcacg acggtgattt ccagtaccct
    39241 gctcaaccga tctgaaacag cggagcatct ggcaaaaaaa cgccaattgt ggacctatat
    39301 tcagcagaaa aatccagaag tctttcaggc tattcgtaag accatgttga gccgtttgac
    39361 caaacattct gtcttgccag atcgcaaact gtccaatgtc gtctatcaaa tcaccaaatc
    39421 tgtttatgga tttaattaat ataagtgttt tataagaggg atttaagaaa aattttaact
    39481 ttttcttagt cctttttaat ttcaggagat tatactagag tcatcaaata aagaaagact
    39541 ctaaggagaa tcctatgaaa ttcaatccaa atcaaagata tactcgttgg tctattcgcc
    39601 gtctcagtgt cggtgttgcc tcagttgttg tggctagtgg cttctttgtc ctagttggtc
    39661 agccaagttc tgtacgtgcc gatgtggtca atccgacccc aggtcaagtc ttacctgaag
    39721 agacatcggg aacgaaagag ggtgacttat cagaaaaacc aggagacacc gttctcactc
    39781 aagcgaaacc tgagggcgtt actggaaata cgaattcact tccgacacct acagaaagaa
    39841 ctgaagtgag cgaggaaaca aactcttcta gtctggatac actttttgaa aaagatgaag
    39901 aagctcaaaa aaatccagag ctaacagatg tcttaaaaga aactgtagat acagctgatg
    39961 tggatgggac acaagcaagt ccagcagaaa ctactcctga acaagtaaaa ggtggagtga
    40021 aagaaaatac aaaagacagc atcgatgttc ctgctgctta tcttgaaaaa gctgaaggga
    40081 aaggtccttt cactgccggt gtaaaccaag taattcctta tgaactattc gctggtgatg
    40141 gtatgttaac tcgtctatta ctaaaagctt cggataatgc tccttggtct gacaatggta
    40201 ctgctaaaaa tcctgcttta cctcctcttg aaggattaac aaaagggaaa tacttctatg
    40261 aagtagactt aaatggcaat actgttggta aacaaggtca agctttaatt gatcaacttc
    40321 gcgctaatgg tactcaaact tataaagcta ctgttaaagt ttacggaaat aaagacggta
    40381 aagctgactt gactaatcta gttgctacta aaaatgtaga catcaacatc aatggattag
    40441 ttgctaaaga aactgtcgaa aaagctgtta
//
LOCUS       DAVBCA010000013        39608 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.013, whole genome shotgun sequence.
ACCESSION   DAVBCA010000013 DAVBCA010000000
VERSION     DAVBCA010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 39608)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39608)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39608
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.013"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            470..1591
                     /gene="mnmA"
                     /locus_tag="VQU19_000620"
     CDS             470..1591
                     /gene="mnmA"
                     /locus_tag="VQU19_000620"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HET2479910.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRRLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            1732..2187
                     /locus_tag="VQU19_000621"
     CDS             1732..2187
                     /locus_tag="VQU19_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET2479911.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALIVQNHKLLVTKDKGKYYTIGGA
                     IQVNESTEDAVVREVKEELDVKAQAGQLAFVVENRFEVDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLQNIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            2197..4110
                     /gene="mnmG"
                     /locus_tag="VQU19_000622"
     CDS             2197..4110
                     /gene="mnmG"
                     /locus_tag="VQU19_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HET2479912.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEVPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            4299..4388
                     /locus_tag="VQU19_000623"
                     /pseudo
     CDS             4299..4388
                     /locus_tag="VQU19_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(4534..6213)
                     /locus_tag="VQU19_000624"
     CDS             complement(4534..6213)
                     /locus_tag="VQU19_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HET2479913.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLRLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(6215..6448)
                     /locus_tag="VQU19_000625"
     CDS             complement(6215..6448)
                     /locus_tag="VQU19_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HET2479914.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            6830..7051
                     /locus_tag="VQU19_000626"
     CDS             6830..7051
                     /locus_tag="VQU19_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000184674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2479915.1"
                     /translation="MTNQVLEENYLCDSLLAFSPPRDLCRLVCILLWIKCLDALLMLG
                     FFVWGCRDSRFTTRKFHPIYQDEVVFAFF"
     gene            complement(7264..7416)
                     /gene="cibB"
                     /locus_tag="VQU19_000627"
     CDS             complement(7264..7416)
                     /gene="cibB"
                     /locus_tag="VQU19_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HET2479916.1"
                     /translation="MMKDLNNCREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(7418..7603)
                     /gene="cibA"
                     /locus_tag="VQU19_000628"
     CDS             complement(7418..7603)
                     /gene="cibA"
                     /locus_tag="VQU19_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HET2479917.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            7781..8464
                     /gene="tsaB"
                     /locus_tag="VQU19_000629"
     CDS             7781..8464
                     /gene="tsaB"
                     /locus_tag="VQU19_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HET2479918.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMESLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLTHTLNIELVGMSSLLALVPY
                     QQEGLFVPLMDARRNNVYAGFYENAKPVMPEAHLSFEEVLEKVKGASQVTFVGEVGPF
                     VEQIQEHLPRTNYKETLPNAANLALLAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            8461..8898
                     /gene="rimI"
                     /locus_tag="VQU19_000630"
     CDS             8461..8898
                     /gene="rimI"
                     /locus_tag="VQU19_000630"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HET2479919.1"
                     /translation="MIEIKRIQQQPDLAQAIYAVMAAVYLVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLAVQENLFEAEVLQIAVKGAYQGQGIASALFAQLPTDKEIFLEV
                     RKSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            8888..9898
                     /gene="tsaD"
                     /locus_tag="VQU19_000631"
     CDS             8888..9898
                     /gene="tsaD"
                     /locus_tag="VQU19_000631"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HET2479920.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLYHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(9944..11244)
                     /locus_tag="VQU19_000632"
                     /pseudo
     CDS             complement(9944..11244)
                     /locus_tag="VQU19_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(11520..11871)
                     /locus_tag="VQU19_000633"
                     /pseudo
     CDS             complement(11520..11871)
                     /locus_tag="VQU19_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(11978..12270)
                     /locus_tag="VQU19_000634"
                     /pseudo
     CDS             complement(11978..12270)
                     /locus_tag="VQU19_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            12513..13719
                     /locus_tag="VQU19_000635"
                     /pseudo
     CDS             12513..13719
                     /locus_tag="VQU19_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
     gene            13712..14360
                     /locus_tag="VQU19_000636"
                     /pseudo
     CDS             13712..14360
                     /locus_tag="VQU19_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
     gene            14370..15986
                     /locus_tag="VQU19_000637"
     CDS             14370..15986
                     /locus_tag="VQU19_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2479921.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTNQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNIC
                     YKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLSGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
     gene            16006..16850
                     /locus_tag="VQU19_000638"
                     /pseudo
     CDS             16006..16850
                     /locus_tag="VQU19_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813546.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            16918..18419
                     /locus_tag="VQU19_000639"
                     /pseudo
     CDS             16918..18419
                     /locus_tag="VQU19_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819023.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase"
     gene            18431..19180
                     /locus_tag="VQU19_000640"
     CDS             18431..19180
                     /locus_tag="VQU19_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HET2479922.1"
                     /translation="MSDNTKYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSKLKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFPYVSDSSMVSYMGKTKELKMYQEELDEKHYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIRFWIKK"
     gene            19193..20365
                     /locus_tag="VQU19_000641"
     CDS             19193..20365
                     /locus_tag="VQU19_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HET2479923.1"
                     /translation="MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKGTLP
                     SKNEELMKFFCENNLNITFFDTFSEIKNNIDYYIIALPTDYDEKIGSFNTYEIEQTVS
                     KILRVKPNGKIILKSTVPIGFSNKLKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVV
                     GDETVEGRKIAELFLSISTHSTANIKNVMLVSPTEAEAIKLFSNTFLALRVAFFNELD
                     SFAERRSLNAEVVIKGVCLDPRIGNFYNNPSFGFGGYCLPKDTRQLKKEFIEINAPVI
                     EAIDISNTNRKQFIVKQILERKPKIVGIYKLGMKYNSDNYKESAILSIINELLIVGIK
                     ILVYEPNLNVSIDNVIFEKNFELFIKQSDLIVANRWDRGLEAYKDKVYTRGIWIRD"
     gene            20760..21623
                     /locus_tag="VQU19_000642"
     CDS             20760..21623
                     /locus_tag="VQU19_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HET2479924.1"
                     /translation="MIEKMELGEFYKELRLARKLKQSDVACAGLTASQLSKFELGQSM
                     LSADKLILAIQGINMNFDEFGHKLNNYQESPHMRIGRRVVDCFSHQDIAALEQLLEEV
                     DQEQMAQTYRRLNAIVIKNALHSLDKSYPLTEEDSEFLTTYLYAIESWTWFELYLFCN
                     TMPFLSNQDLIFLSTSLLEKSKEFKELVHNRWYMKSGYLNIISELMERKLFSYIPIFE
                     AELERMLRPYDVFEKVLWQFLKKMQIFLQTKGSNQKEIEHFIQSLQVLENPQLTALFE
                     LRLQQYKELID"
     gene            21909..22142
                     /locus_tag="VQU19_000643"
     CDS             21909..22142
                     /locus_tag="VQU19_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2479925.1"
                     /translation="MLNLQFAETMELTEAELQDVRGGNLVNSMGGGGRSGISGWGVPG
                     IYPGWGNQGMSPNRGAFDWTIDLADGLFGRRRR"
     gene            22164..22841
                     /locus_tag="VQU19_000644"
     CDS             22164..22841
                     /locus_tag="VQU19_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2479926.1"
                     /translation="MKKMKEVKFHLATGLLILTYYLIFNVTSDLDFMVALSDNMYYVF
                     QVLLVLILGTIATIAFVKSEHWKECGRFQFRWSYLGVFLLSFFLLFVWANLTTYIFPR
                     TQNGSTVVEVATSLTGISYFVTRILYTSIIAPVSEEVVCRGLLMTSLSKVKRYYLDVL
                     VSAAIFGAMHVLQYGWITTDFIKYFGMGLIFCMMFRYTRSIYWAIALHASWNSFLLIV
                     TLLVFGY"
     gene            22853..23518
                     /locus_tag="VQU19_000645"
     CDS             22853..23518
                     /locus_tag="VQU19_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2479927.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVAGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVAWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEDMIYRGLVMTALEKGKKWGLDVL
                     GSAILFGVSHISNHGWVLTDFFVYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            23590..24816
                     /locus_tag="VQU19_000646"
     CDS             23590..24816
                     /locus_tag="VQU19_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET2479928.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQVLQIFLGVLADFQHHRVLKYTVISFTKFLLYSIVSLSLSGQSFSLL
                     LVTFICLLNLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTISYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPISTLFLRNQPFLNLQTGQSLALLATLEL
                     SALILGSLMSGYLQHTISIKIALYASLLLQLLLLVGFATAHFGLILIFSFLDAFFAGI
                     LSPRLQELVFKQIPEESMGAVQSSIGAITVVLPSLFTIALGTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
     gene            complement(25167..25244)
                     /locus_tag="VQU19_000647"
                     /pseudo
     CDS             complement(25167..25244)
                     /locus_tag="VQU19_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            25315..25971
                     /locus_tag="VQU19_000648"
     CDS             25315..25971
                     /locus_tag="VQU19_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HET2479929.1"
                     /translation="MPTALGYVSIGLACGTIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFGLDFALVGMFIGI
                     FASQFQIMQRRIPVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGVVLDGQ
                     "
     gene            25961..26284
                     /locus_tag="VQU19_000649"
     CDS             25961..26284
                     /locus_tag="VQU19_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HET2479930.1"
                     /translation="MVSKYLLLAVIFSDLVTWILRMIPFILVKYKGLPAIVERFLKFL
                     PVSIIFALILSSVVTGKVGSLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAV
                     LRLVF"
     gene            26388..27218
                     /locus_tag="VQU19_000650"
     CDS             26388..27218
                     /locus_tag="VQU19_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2479931.1"
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGQAASKKEIIVAT
                     NSSPKPFNYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYQMAV
                     NNISYTKERAEKYLYAAPTVKDPNVLVVKKDDSSIKSLDDVGGKSTEVVQGTTSAKQL
                     EDYNKQHSDNPTILNYTKANLQQIMGHLSDGQFDYKISDKITVETVIKNQGLDNLKVI
                     DLPSDQQPYVYPLLAKGQDELKTFVDKRIQELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            27259..27336
                     /locus_tag="VQU19_000651"
                     /pseudo
     CDS             27259..27336
                     /locus_tag="VQU19_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC protein"
     gene            27440..28270
                     /locus_tag="VQU19_000652"
     CDS             27440..28270
                     /locus_tag="VQU19_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2479932.1"
                     /translation="MKKIVKYSSLAALALVAAGVLAACSGGAKKEGQAASKKEIIVAT
                     NGSPKPFIYEENGELTGYEIEVVRAIFKDSDKYNVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            28424..29278
                     /locus_tag="VQU19_000653"
     CDS             28424..29278
                     /locus_tag="VQU19_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HET2479933.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            29378..30751
                     /locus_tag="VQU19_000654"
     CDS             29378..30751
                     /locus_tag="VQU19_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HET2479934.1"
                     /translation="MVFPSEQEQIEKFEKDHVVQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            30744..31805
                     /locus_tag="VQU19_000655"
     CDS             30744..31805
                     /locus_tag="VQU19_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HET2479935.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSGLSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSNPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGGQ"
     gene            31807..32499
                     /locus_tag="VQU19_000656"
     CDS             31807..32499
                     /locus_tag="VQU19_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2479936.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(32529..33098)
                     /locus_tag="VQU19_000657"
     CDS             complement(32529..33098)
                     /locus_tag="VQU19_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HET2479937.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIALFFLGTKHGAGSFLPGIICGLLADGVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            33233..33847
                     /locus_tag="VQU19_000658"
     CDS             33233..33847
                     /locus_tag="VQU19_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HET2479938.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKVLLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            33849..35495
                     /locus_tag="VQU19_000659"
     CDS             33849..35495
                     /locus_tag="VQU19_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET2479939.1"
                     /translation="MKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHIGETVDR
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQKYFEHRASYSDQRQ
                     SIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            35507..36793
                     /locus_tag="VQU19_000660"
     CDS             35507..36793
                     /locus_tag="VQU19_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2479940.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQDWQIFISDQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVPYIKETLSSFFGQYRMNENVVSVLEVIGCD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            36854..37387
                     /locus_tag="VQU19_000661"
     CDS             36854..37387
                     /locus_tag="VQU19_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2479941.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRTAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKASAEEEETEELA"
     gene            37465..37935
                     /gene="nrdI"
                     /locus_tag="VQU19_000662"
     CDS             37465..37935
                     /gene="nrdI"
                     /locus_tag="VQU19_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HET2479942.1"
                     /translation="MKIISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(38228..39490)
                     /locus_tag="VQU19_000663"
     CDS             complement(38228..39490)
                     /locus_tag="VQU19_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HET2479943.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFSGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
BASE COUNT        12026 a         6862 c         8542 g        12178 t
ORIGIN      
        1 ttaggtgccc ttgcagtcaa cacaactgta gatggctata aagtcaatgc caatggtgaa
       61 tgggtttaag ccgattaaat taaatcatgt taagaacatt tgacatttta attttgaaac
      121 aaagataagg ttcgattgaa tagatttatg ttcgtattct ttaggtacct atcttatgat
      181 ttcaggaaat gtcattaaaa aaacgactcc ttttctctaa cttgaaaaat agattagaga
      241 aaatgggttg ttttatttat tatagttatt tgaatgaaga taagaagaag gtatactcac
      301 atcattcaca taatctgtat gttgactata agtttaaaaa aacaattttt aagctcttcc
      361 ttgtcttctc caaccaagcg tgttataatg aatactgctc aagcgacctt caatcgtgaa
      421 gcacacacga ccttcaatcg tgaataaacg aatagatggg agacttacca tgagtgataa
      481 ctctaaaaca cgtgttgtcg tggggatgag tggtggtgtt gattcgtcgg tgacggctct
      541 tttgctcaag gagcagggct acgatgtgat cggtatcttc atgaagaact gggatgacac
      601 agatgaaaac ggcgtctgta cggcgaccga agattacaag gatgtggttg cggtggcaga
      661 ccagattggc attccctact actctgtcaa ttttgaaaaa gagtactggg accgcgtttt
      721 tgagtatttc ctagcggaat accgtgcagg gcgcacgcca aatccggacg ttatgtgcaa
      781 caaggaaatc aagttcaagg cctttttgga ctatgccatg accttggggg cagactatgt
      841 agcgactggg cattatgctc gagtggcgcg tgatgaggac ggcactgttc acatgcttcg
      901 tggcgtggac aatggcaagg accagaccta tttcctcagc caactttcgc aagaacaact
      961 ccaaaaaacc atgttccctc tgggacattt ggaaaagcct gaagtacgca gactagcaga
     1021 agaagcaggc ctttcgactg ctaagaagaa agactcgaca gggatttgct ttatcggaga
     1081 aaagaacttt aaaaactttc tcagcaacta cctgccagct cagcctggtc gcatgatgac
     1141 tgtggatggt cgcgatatgg gcgagcatgc aggtcttatg tactatacaa tcggtcagcg
     1201 tggcggactc ggtatcggtg ggcaacacgg cggtgacaat gccccttggt tcgttgtcgg
     1261 aaaagatcta agcaagaata ttctctatgt aggacaagga ttctaccatg attcgctcat
     1321 gtcaactagc ctagaagcca gtcaagtcca ctttactcgt gaaatgccag aagagtttac
     1381 gctagaatgt acggctaaat tccgttaccg tcagcctgac tctaaggtga ccgtccatgt
     1441 caaaggagac aaggcagaag ttatctttgc ggaaccacaa cgcgcgatta caccaggaca
     1501 ggcagttgtc ttttacgatg gcgaagagtg tctaggtggc ggtttgattg acaatgctta
     1561 ccgcgatgga caagtttgtc agtacattta gattgacaaa ttttctcaat ttgctacaat
     1621 aataacagca atagaaatga tggtcaaagc tcatggatgt tgcaggcttt tttgtcctgc
     1681 acttctttgt agttttgact gtttttgtgt cgtttaaggg aaaggacaag aatgactcaa
     1741 caagactttc ggacaaaagt agacaatacg gtttttggtg ttcgggctac agccttgatt
     1801 gtccaaaatc acaagcttct agttaccaaa gacaagggca agtattacac tattggaggt
     1861 gcgattcaag tcaatgaaag cacggaagac gcggtagtcc gtgaagtgaa ggaagaactg
     1921 gatgtcaaag ctcaagctgg gcagctagct tttgtggttg aaaatcgttt tgaagtggac
     1981 ggcgtttcct atcacaatat cgagtttcat tatctggtgg atttgcttga agatgccccg
     2041 ttgaccatgc aggaagatga gaaaaggcag ccctgtgagt ggattgactt ggataagctc
     2101 cagaatatcc agctagttcc agccttttta aaaacagccc taccagattg ggaaggccaa
     2161 ctaagacaca ttcatcttga ggaataggag agaaacatga cttatcattt tactgaagaa
     2221 tacgatatta ttgtaattgg tgcgggacac gctggggttg aggcttcctt ggccgctagc
     2281 cgtatgggct gtaaggtcct gcttgcgacc atcaatattg aaatgctggc tttcatgcct
     2341 tgtaatccct ctatcggtgg ttctgctaag gggattgtcg tacgtgaagt cgatgccctc
     2401 ggtggcgaga tggccaagac cattgacaag acttacatcc agatgaagat gctcaacaca
     2461 gggaagggac cagccgttcg tgcccttcgt gcgcaggctg ataaggaact ttactctaag
     2521 gaaatgcgca agacagttga aaatcaagaa aatctgaccc ttcgtcaaac catgattgat
     2581 gagattttgg tggaagatgg caaggttgtc ggtgtgcgta cagccaccca tcaagaatat
     2641 gctgctaagg ctgttattgt gacgacaggg actgctctcc gtggggaaat tatcatcgga
     2701 gacctcaagt actcatcagg tcctaaccac agcttggctt ctattaacct agctgacaat
     2761 ctcaaggaac tgggtctcga aatcggtcgt ttcaagacag gaacccctcc acgtgtcaag
     2821 gcttcttcta tcaattacga tgtgacggaa attcagccag gagacgaagt gcctaatcat
     2881 ttctcataca cttcacgtga tgaggattat gtcaaagatc aagtgccatg ctggttgacc
     2941 tataccaatg gtaccagtca tgagattatc caaaacaacc tccaccgtgc gcctatgttt
     3001 acaggtgtgg tcaagggagt ggggcctcgt tactgtccgt cgattgaaga caagattgtg
     3061 cgctttgcgg acaaggaacg tcaccaactc ttccttgagc cagaagggcg caatactgag
     3121 gaagtctatg ttcaaggact ttcaaccagt ctgcctgagg atgtccagcg tgacttggtt
     3181 cattccatca aaggtttgga aaatgcagag atgatgcgga caggttatgc tattgagtat
     3241 gatatggtct tgcctcatca gttgcgtgcg actttggaaa ccaagaaaat ctcaggtctc
     3301 ttcactgctg gtcagacaaa tggaacatca ggttatgaag aagctgctgg ccaagggatt
     3361 atcgcgggta tcaatgcggc tctgaaaatc caaggtaaac ctgagttgat tctaaaacga
     3421 agtgacggtt atatcggggt gatgatcgac gacttggtga ccaagggaac cattgaacct
     3481 taccgtctct tgaccagtcg tgctgaatac cgtctcattc ttcgtcatga caatgctgat
     3541 atgcgcttga ctgagatggg acgcgagatt ggccttgtgg atgatgaacg ctgggctcgt
     3601 tttgaaatca agaaaaatca atttgataat gagatgaaac gcctagacag tatcaaactc
     3661 aagccagtca aggaaaccaa tgctaaggtt gaggaaatgg gcttcaagcc gttgacagat
     3721 gcggtgacag ccaaggaatt ccttcgccgt ccagaagttt cttaccaaga tgtggtggcc
     3781 ttcatcggac cagctgcaga agacttggat gacaagatta tcgaattgat tgaaacagaa
     3841 atcaagtacg aaggctatat ttccaaagcc atggatcagg ttgctaagat gaaacgtatg
     3901 gaagaaaaac gcattccagc caatatcgac tgggatgaca tcgattctat tgcgacggaa
     3961 gctcgtcaga agttcaaact catcaatcca gaaaccatcg gccaagccag ccgtatttcg
     4021 ggagtaaacc cagcagatat ttctattttg atggtgtatc tggaaggtaa aaatcgtagt
     4081 atttctaaaa ctcttcaaaa atcaaaatga tacgtcgtcg gcttcttacg aatgagttca
     4141 aagcttggct ttgattcatc tccaacctcc catagttccc cgaactatgg gagctaactc
     4201 aagttatgca ttttcctagc cttctggtct gattttcatt gagttttaat ctcaaaagaa
     4261 agcatagaga aaaacagctc cgaagacggg gctgttttgt tgacttgtac tcaatgaaaa
     4321 tcaaagagca aactaggaag ctagccgtag gttgctcaaa gcactgcttt gaggttgtag
     4381 atagaactga cgaagtcagc tcaaaacaca gttttgaggt tgtagataga actgacgaag
     4441 tcagctcaaa acacagtttt gaggttgtgg atagaactga cgaagtcagt aacatatata
     4501 cggcaaggcg aagctgacgt ggtttgaaga gtattattct tcatctggtg tgaggatcat
     4561 cgggatgatg atcggttcac gttcggtatt ttcatagagg aaggggcgaa tagcgttgac
     4621 aatggcacca ttgacagatt gcacgctagc atccttattt ttcagtgcga tacgaatggc
     4681 attgaagagg atacgctggc tttggcgaat caagtctcca gactctctca tgtagacaaa
     4741 gcctcggctg aggatatctg ggccagacag aatcatctgc gatttgaagt caacagttgc
     4801 gactgccaga acgacaccgt cttcagatag atcgcgacga tctttgagga cagctgcgcc
     4861 aatttcaccg atacgatttc catcgacata gatatcttgg gcgttgaaat gacctgcgat
     4921 acgagctgag tcagcagtaa gggcaagcac atcgccattg ctcatgataa agatattgtc
     4981 tttctcaaca ccagtatcca ctgctagtcc agcgtggact ttttgcatgc ggtattcacc
     5041 gtggacaggc atgaagtatt ttggcttaat caagcggagc atgagttttt gctcttgctg
     5101 accaccgtgt ccagatgtat ggatattgtt cactttaccg tggataactt cgacaccagc
     5161 ttcagaaatg atgttaatca gcttgttgac gctagtagtg tttccaggga tgggactaga
     5221 agagaagata acggtatcac ctggttgtaa ttgtacttga cggtgggttc cgttggcgat
     5281 acgagagagg gctgccatag gctcaccctg actacctgta cagaggataa gaacttctcc
     5341 tgcaggataa tctttgattt catttggctc gataaaggtt cccttaggag ctttgatgta
     5401 gccaagatcg attccgttga caatggcctt ttccatagaa cgaccaaaga ccgcaatctt
     5461 gcgtccagtc ttaacagcag cttctgttgc ctgctggaga cggaagatat ttgaggcaaa
     5521 ggatgcaaag atgatacgtc cttcaatacc ttggataatc ttcataatgg actgaccaac
     5581 gactttttca gagttggtaa aggttggtac ttccgcattt gtcgagtcag acaggagaca
     5641 gagcacgcct tcttcaccaa gcgcagccat acgatgcaag tccgcaggtt ctccaactgg
     5701 agtaaagtcg aacttaaagt cacccgtaca gacgattttc ccttgaggag tatgaatgac
     5761 aatccccaaa ggctctggaa tagagtgagt cgttctaaag aaagttgcct tgagattttt
     5821 aaaggtcaac tcggtgttgt ggttgatttc gtaaagtttg gcgttgcgca agaggccgtg
     5881 ttcttcgagt ttcccacgga tcaaagccaa ggcaagcggt ccagcgtaga tagggacatt
     5941 tgcttgcttg agtaggaacg gaatcccacc aatgtggtcc tcgtgtccgt gtgtgattaa
     6001 aacagccttg acgcggtcga tattgtctac gatgtaagag tagtcaggaa tgacatagtc
     6061 gataccaagc aagtcatctt ctgggaattt aatcccagca tcgacgatga taatctcgtc
     6121 ttggtattca attccgtaag tgtttttccc gatttctcct agaccaccga tggcaaaaac
     6181 accgacttct tcaggtttaa gagtgtaggc catattagaa ctccgtaatt tcgaaggcgc
     6241 cagtttcttt ttcgtaatcg agcaatttgt cagacaagag ttcgatatat tcgatattgt
     6301 actctgggcg attttcttcg acaagttggc gagcagtgat acggccctca agttctgagc
     6361 tggcatcgat gtctaggtaa agcgcgcgtg ttgtttcacg gcgtgggcta cgttcttttg
     6421 tttcttgata aaaaactttg taaatcatat agttcctttc tatttacagg tcagcttatt
     6481 ccaaactttt agcagatatt tgcttgattt cattccattt tgtgtctaga ttgaccttga
     6541 ttcgttacaa ttatttcaat tataccacaa aatgaaaaat tagtaaaaga cggaaacgag
     6601 aaagttaggg gacgatttct tcggtaagcg tttgcaaaaa caaagaaaat gtgttatgtt
     6661 gataacggaa gtgaagttta ttacttgtca taattccata tagattttaa gtcaaggagg
     6721 ttgccctatg tataacttat ttgcttttgc tatcggagtt cgtttgctag cttttatcgt
     6781 ttttgttttg cgtttatgga ggaaatcttc tatttgccaa actggaacga tgacaaacca
     6841 agttcttgag gaaaattacc tttgtgactc tctactcgct ttttctcctc ctcgtgacct
     6901 atgtcgtttg gtttgtattt tactttggat taaatgctta gatgccctgc ttatgctggg
     6961 gttttttgtt tggggatgta gagatagtag atttacgaca cgaaaattcc accccatcta
     7021 tcaagatgag gtggtctttg catttttcta aaatgatatg acaatggaat tttcaaagct
     7081 tattattttt atgggagtca ttgttctgct caaaaataga gttgaagcat aaaaataaaa
     7141 caatacaaac agataaatcg aatggtaaag ggatggtagt aatgttcaaa tcattgagaa
     7201 tgctgagcaa actgtaagag atgaagacaa taaaatttat ccttctaaaa atgtgtttct
     7261 tatctagcat gacttaccaa actttttacg aaggtctttt ccaatggtat aacctgccat
     7321 aaataaagcg ataccaacac ctacaccaaa gccacccttg atttcttgca attccttatt
     7381 agaaatttca cgacagttgt tcaaatcttt catcatatta atctcctcct aaaaaataac
     7441 cagctgccaa accagaacct ataagtgctg ttccacctgc aatagctttc caagatactg
     7501 ctactccaaa gataaccaag ggagcgagac cgccatcaat atctgataat tcattttcag
     7561 ataaggataa aaattgattg tcaagaatgt caaaatttgt cattgaactt tcctcctttt
     7621 ttcttgttca cttttatatt cggaaaagaa aaggaaaagt gagcattttt ttaaattatt
     7681 tttagttaag tgagggcact cttgtctggg ggcaaagaaa attcccatgt gccatctttt
     7741 gtagtataat agtaagcaga caaaaagata ggaatgtgtt atgaaagtat tagcttttga
     7801 tacgtccagc aaggctcttt ctctcgctat tttagaggat aagcaggttc ttgccgagac
     7861 gacgattaat atcaagaaaa atcacagtat taccctcatg ccagccattg attttttgat
     7921 ggagagtttg gactggacgc ccaaggattt ggaccgaatc gtggtggcgg aagggccagg
     7981 tagctacaca ggcttgcgaa tcgcggtagc cactgccaag accttgactc atactctgaa
     8041 cattgagtta gttggtatgt ctagcctctt ggctctggtg ccatatcaac aagaaggctt
     8101 gttcgttcct ttgatggatg cgcgtcgcaa caatgtttat gcaggatttt atgaaaatgc
     8161 taaacctgtc atgccagaag cgcacctatc ttttgaagag gtgctagaaa aagtcaaggg
     8221 tgctagtcag gtaacctttg tcggagaagt tggccccttt gtggagcaga ttcaagaaca
     8281 cttgccaagg actaattata aagaaacctt gcctaatgca gccaatcttg ctcttttagc
     8341 ttgggacaag gaagcagact ccttgcatga ttttgtgcca aattacctca aacgagtcga
     8401 ggctgaggaa aactggctca agaaccatac cgagtctggt gagtcctaca ttaaacgcct
     8461 atgatagaaa tcaagcgaat tcaacaacag cctgacctag ctcaagccat ctacgctgtt
     8521 atggcagctg tttacctagt cagtccttgg actctggagc aaatccaagc agatctgtcc
     8581 caagaccaga cttggtatgc attggcttat gatggggcag aagtgattgg atttctagct
     8641 gtgcaggaga atctttttga agcagaagtc ctgcaaatcg ctgtcaaagg agcttatcag
     8701 ggtcagggaa ttgcgtcagc cttgtttgct caattgccga cagataagga gattttcctc
     8761 gaagtcagaa agtcaaatca acgagcgcaa gcattttaca agaaagaaaa aatggcggtc
     8821 atcgctgagc gaaaggccta ctaccatgac ccagtcgagg acgccattat catgaagaga
     8881 gaaatagatg aaggatagat atattttagc atttgagaca tcctgtgatg agaccagtgt
     8941 cgccgtcttg aaaaacgacg atgagctctt gtccaatgtc attgctagtc aaattgagag
     9001 tcacaaacgt tttggtggcg tagtgcccga agtagccagt cgtcaccatg tcgaggtcat
     9061 tacagcctgt atcgaggagg cattggcaga agcagggatt accgaagagg acgtgacagc
     9121 tgttgcggtt acctacggac caggcttggt cggagccttg ctagttggtt tgtcagctgc
     9181 caaggccttt gcttgggctc acggacttcc actgattcct gttaatcaca tggctgggca
     9241 cctcatggca gctcagagtg tggagccttt ggagtttccc ttgctagccc tcttggtcag
     9301 cggcggacac acagagttgg tttatgtttc ggaggcagga gattataaga ttgttgggga
     9361 aacccgtgat gatgcggttg gtgaggctta tgataaggtc ggccgtgtca tgggcttgac
     9421 ctatcctgca ggtcgtgaga ttgacgagct ggctcatcag gggcaggata tttatgattt
     9481 cccccgtgcc atgattaagg aagataatct ggagttctcc ttctcaggtt tgaaatctgc
     9541 ctttatcaat ctttatcaca atgccgagca aaagggagaa agcctgtcta cagaagattt
     9601 gtgtgcttcc ttccaagcag cagttatgga cattctcatg gcaaaaacca agaaggcttt
     9661 ggagaaatat cctgttaaaa ccctggttgt ggcaggtggt gtggcagcca ataaaggtct
     9721 cagagaacgc ctagcagccg aaatcacaga tgtcaaggtt atcatccccc ctctgcgact
     9781 ctgcggagac aatgcaggta tgattgccta tgccagcgtc agcgagtgga acaaagaaaa
     9841 cttcgcaggc tgggacctca atgccaaacc aagtcttgcc tttgatacca tggaataaag
     9901 agtggctctt tgtcaagtgt agtgggtagt cgaaaagctg caatctggag agtacgaaat
     9961 tcgtactctc ttttttgatg ttcaaagtca tcaaaatccg ttttttaaaa ttgttaaagt
    10021 tccggaaacc aaaggctttg cgcttgataa tcttaatcaa attattggtc gcttcaagtt
    10081 tagcgttgga ataaggcagc ttaagtgcgt tgataatctt atctctatcc cttaaaaaag
    10141 tccaaaagac cgtttgaaaa agcggatgaa ccgttggcag ttcttgctca atcaatccaa
    10201 agaaatggtc ggcattcttc tcttgaaaat gaaagagcag gagttgatag agttcgtagt
    10261 gaacctgtaa tccctcagag taagaaagca gcttatctcg tacttcccga tgggttaagt
    10321 gcattcgaaa cgtgggctga tagaatcgtt tctgacagag cttgaagcta tactggtgta
    10381 gtaaatcagt ccagtggact gatttagccc gagcctagaa acgaaaaagc gagggttcca
    10441 aaagcgcttg agcgcccgat actccaagga ttttcggtca aattggttca tgatttggat
    10501 tcgtactcgg ttcatagctc ggctcagatg ttggacaatg tggaagcggt caagaacaat
    10561 cttcgccttt ggaaagagtt gcttagcgag ccgataataa gggctgtaca tgtccatggt
    10621 gatgacctcg accagctccc gaacctctct ctgatagcgt tggaaatggt ttcgaatcac
    10681 cgcatgagtt cgcccgtcta aaattgcgag gatggatttg gactcaaaat cttgggcaat
    10741 gaagctcatt ttgctctttt tgaagctata ctcatcccaa ctcataactt ttggcaactt
    10801 ggtccaatcg gtttcaaact taaattccct cagttttcgg atgacggtgg aagttgagac
    10861 cgccaatctg tgggcaatct cagtcataga ctgcttttca aggaggagct gagcgatttt
    10921 ttgtctcacc atgttggaaa tctggcaatt tttcttgaca atggatgttt gagaaacgac
    10981 caccttaagg caattcttgc actgaaagcg gcgctttttg agatgcagta ccgtgggtaa
    11041 accctgacag tcgagaagcg gaattttaga ggctttctgg aagtcgtatt tgatcatctt
    11101 cccttgacaa tgaggacaag gaggagcggg ggaatccaac tttgcctgaa cgactagatg
    11161 ggtttggtat ttcagaacag acaagatttt gatatttttg tcttccaatc cgagcaaatc
    11221 tgtggtattc ttaagttgtt ccatatggac cctttctaat gagttggtta gacgcttttc
    11281 attataggtc atatggggct ttttttctac aagaaacgac cctataattc ctggggtggg
    11341 attacccact acagaaatta tagagccaaa gcattccaaa gtcttgtctg actctggaat
    11401 gttttctgtt cacagttgtt ttgtaactgc ctaataagta accgcgctat aacgaggtat
    11461 ctaccgagat tgtcaattct ccagtatact gttataaaaa acaaaactgg aggatttttt
    11521 tatgtcctcc catcgtccca tcgactgttc cgtagctgcc caataacgga gtatagtcgg
    11581 ctgaaacaag aataggacaa aagtgcctca agaaaagcat cgtaatttga caatattatt
    11641 ctgagatgtt tttgatgtaa gcccatattt tctcaatggg attatactcg ggtgaatagg
    11701 taggaagtgg taacagtcta tgccctgctc cttacacatg ttcattctgt gaaaccttgc
    11761 attgtccata atgataaggg atggtgtatc taaagtaggt agtaagaatt tttggaagca
    11821 agcttcgaaa aagtcactcg tcatcgtatc tttataggtc atcggagcca tagtatattg
    11881 aaacaaaaaa gggcattagt acttctataa cagtatcgca atctctggtg tgcgttgtct
    11941 cgatcttaat tcaaataatt atatcttctt ccagagagac taactgcctg ctcaaggctc
    12001 gatcatattt gagataaaaa taggtctcaa cccctgtctc ataaatataa ataggagtca
    12061 ggtagcttaa gtgattcaat tctttaagga accgatttac tttttctggg tcttgttcgc
    12121 agtaggtacg gctcttttta gactatatcc catagccttt agagcgtaat gaatagttgt
    12181 tggaggacag ttgaattcag cagctatttc agtcaaataa gcatcgggat gagtttcaat
    12241 atagatcttt aatttatctc tatcaacttt ttcaattaat agtggaagtt ttcttaaagt
    12301 tagtgtgttg aaacgttttt atacagtgct aaaatttgaa gtgtagtgca gatgtatttg
    12361 taatagtatt atagcaattc tttggagaag gtcgagacaa gagaaaatag gtatctttga
    12421 gatataagta tgatttacta taaaattatt gagttattca taaaaatttc tctatcaaat
    12481 atcataatgc gtcgtttaag gagatggtta caatgcaata tagttgtgga aaaataaata
    12541 ttaatatccc tgatggatat ggagacatta aggatatagt gttttcggct catattatag
    12601 ttaggtataa taatggacat tgtggaggta tagatccgca tataattgga ctttgtaaaa
    12661 agcagatcag aaggatgtct ccatatccta ttttgataat cgtatctaga gattcaaagg
    12721 ttattgatga ttataaaaat ttagatattg cctatgttga ttgtactcaa tgttcaaata
    12781 attttgaaac tgccttacac gttaaaaata ttttaaaatt attaaaaatc caacttatac
    12841 actgtcatgg ctactcaact aattattttt tatatatgtt aaaaaaactt gacaagaatg
    12901 gatttggaaa ggttaagaca gtgataacat gccatggatg ggttgaatat aacttaaaaa
    12961 agaaattctt gacttatttt gatttttgga catattctat gggagatgct tttatttgtg
    13021 tatctgaaac tatgaaaaaa agattggaga gtataataaa aaaataagaa gatagttgca
    13081 ataaataacg gaattaatgt atcaaatagc gatttagatg tagtaggtgt tcaagacttt
    13141 aaaaaagaat tttgtattcc aaataacaaa aaaatcattt gttatgttgg aaggttggat
    13201 ccagaaaaaa ggccggatag attccttgaa tttgcagaaa aattattttt agtcagagaa
    13261 gatgtgattt ttattatggc tggaaatggt agtatgtggg ctactttgaa agaaaaaatt
    13321 tgccatttga aatgtagaga taatttcagg ttacttggtg aaatctatcc agctactata
    13381 gtttaccaaa tatcggattt attgtatatt ccttctgata cagaaggaat acctatgtgt
    13441 gttttagagt caatgtcaca agaaactccg gttttagcta gtaatgttgg cgggttaagt
    13501 gaaattattg aacatagggt tgatggattt ttatttgaga aggaagatgt tgagggagtg
    13561 tgtgcttgtg ctaatttttt actcaatgat tctgagtatt tgaaatatat aggtgagaat
    13621 agtaaatcaa aaataagaaa acatttttct gtgcaaaaaa tgtttgtaga aaccatgaga
    13681 gtatatgatg aattattaga gaagagtagt catggatagg aatatagatc aagaattagt
    13741 aagtattata ataccaacac ataataggta tgaatctctg attagagctg tgaaaagttg
    13801 tttacatcaa agttataaaa atatcgaagt tataattatt gatgataatt atagtaatgt
    13861 aaatttaaga aataaaatta tccatcaatt tggctatacc agtcatagaa ttaagttaat
    13921 tttaagtaat gaagatttag gtgcaactaa tgccagaaac ataggtatca aaaattctag
    13981 aggtaagtat atatcatttt tagacgatga tgatgaatat atgccagatc gaattttaaa
    14041 gttgatggct tgttttaaaa agagtagaat gaagaattta gctttagttt atagttatgg
    14101 aataataatt tatccaatag gaaatatttt aatttattga gtttcaacga gagaatattg
    14161 gttacaaaga aatattattc tttaaacata aagcggttac tattaatagg agacaaatgc
    14221 aaggctttaa aagtaatcaa gaaggcaaga gaagaaaaaa tttttaacga atttcttttt
    14281 cgaaatatat gttattatat cattttggtt ttttctattg tatatatgac aactatgttc
    14341 aattaaaatt tagaaagtga gaaactattg tgtatactat tataaaatca aatataaaaa
    14401 aatttagttt attaacgata tttattgttg ctggtcaatt attgctaatt tatgcagcaa
    14461 ctattaatgc tctggtgttg aatgaattaa ttgcgatgaa tttagagcgg tttttgaaat
    14521 tgtcaatcta ccaaatgatt gtctggtgtg ggataatatt ccttgactgg gtagtgaaaa
    14581 attatcaggt tgaagtgatc caagagttta atctagagat tcgaaataga gttgccacag
    14641 acatctctaa ctctacctat caagaatttc atagtaaatc atcaggaaca tatctttcgt
    14701 ggctaaataa tgatgttcag actttaaatg atcaggcttt taaacaactt tttttagtaa
    14761 taaaaggaat ttctggtact atatttgcag ttgtgactct taatcactat cattggtcat
    14821 tgactgtagc caccttgttt tcattaatga ttatgctact tgtaccaaaa atctttgcat
    14881 cgaaaatgcg agaagttagt ctaaatttaa ctaaccaaaa tgaagctttt ttaaaatcta
    14941 gtgagactat attgaatgga tttgatgtgt tagcgtcctt gaatctttta tatgtattgc
    15001 ctaagaaaat taaagaagca ggaattttat taaagatggt tatacaaaga aagacaactg
    15061 tagaaacgtt agcaggcgct attagcttct ttctcaatat tttttttcag atatctctcg
    15121 tttttttaac aggctatctt gcaataaaag gaatagtgaa aattggtact attgaagcaa
    15181 taggagcact aacaggtgtt atttttacag cgctaggtga attaggaggt caattatcct
    15241 ctattattgg tacgaagcct atttttttaa aattgtattc aattaatcca attgagtcaa
    15301 ataaaatgaa tgatatcgaa ccaaatgagg tgaatagaga ttttccgtta tatgaagcaa
    15361 aaaatatttg ctataagtat ggagataaag aaatattaaa aaacttaaat ttttgttttc
    15421 aacgtaatga aaagtattta attttaggtg aaagtggaag cgggaaatct acattattaa
    15481 aattattgag tggctttttg agagattata gtggagaatt gcgattctgc ggggatgata
    15541 taaaaaaaac ctcctattta aatatggttt cgaatgttct atatgtagat caaaaagctt
    15601 atttgtttga aggtacgatt agagataata ttttattgga agaaaattat actgatgaag
    15661 aaatactaca gtctttagag caagttggtt tgagtgtaaa agattttcct aataacattt
    15721 tagattatta tgttggtgat gatgggagat tactgtcagg agggcagaaa caaaaaatta
    15781 ctttagctag agggctaatt agaaataaga aaatagtatt aattgacgag ggaacttctg
    15841 ctatcgatag gagaacttcg ttagcgattg aacgtaagat attagataga gaggatttga
    15901 ctgtcattat tgttacccat gctccgcatc cggaacttaa acaatatttt actaagatat
    15961 atcaatttcc aaaggatttt atttaagaat ataggggagg gaaacatgag attctattgt
    16021 gaagcttatg aggtaattac tgaagagaaa aaagtatact ttaatgatat tgagttagaa
    16081 gttaagtatt cctctgtcga agaattgttt ataatatgtg agaaattatt agataagaaa
    16141 aaagtatcat ttttttatgt atatgagaaa cccttaaggt atctgttatt tgactatata
    16201 tttctactag ttctagctaa aaaaaatatc ccaatcttag atggagtttc caataagcaa
    16261 gttgatccaa cgttgctgca tcacttttct ttggaaattg aaaagaattt tatcgatttt
    16321 tgctataaaa atatggatct catcctaaaa actcaaagta tatctttgtg tcatagagaa
    16381 gagcttatta ttgtagatgt ttcagatgac tctaaatttg gtgtttttta caagcgtttt
    16441 agaacactgg ttgataaaaa taacggaaaa tatgtttgtg tttataattt cagtcgtgtt
    16501 tcagatatac tgcaaaactg gaaaaattat tgcaatcgaa aattttcggt tacgtttact
    16561 gaaagccaat ttgaattatt taagctttta tataatcaaa aaaattttaa aacaatttcg
    16621 ttgctatttg gaaaaaaatt gttgctggag gaattatcta ttatagcgat cttactaata
    16681 tagaatactt ttgtattttt tggtgggata gtatgtttgg gaaagattct attggaaaat
    16741 acgtatatgt agaagagatt agtagatgtc attttttaga tagaaattat tctttttgtt
    16801 atggtttaca agattataaa agtaaactta ttaaatattt tttagaatag ttaatctatt
    16861 cgagagagat aaagaaatat ggaaaatact ttattgaata tcacaggaag cttcgatatg
    16921 gaaactagga atctaattag ttattcttta actgatatct ttgaaacaga taaaataaga
    16981 attgaacttc ttggagaaat ttattataaa aatataaagt tggaattgca tgaattcgct
    17041 ggattgtata agatttatgg aattagctta ataaagaata ttaccggaat gtttttaatt
    17101 ataatttttg atacgaagac aaaagaatta aaaatttttc aagatataac gacttcatac
    17161 tttaatttat actatactgt ttatggaggt gtgttctata tatagtacat ctttaaagaa
    17221 agtgatgaag ttatctcatg ttcccgttac cttaaataac aaaaaaatac aagaatttat
    17281 gagaaatgga tttattttag attcaaatac tttagtaacc gaaattaata aattagaata
    17341 tttctcttac atttctgtaa ataatactct tcgtatatgt ggtattgatt ataatgattc
    17401 aaacaatttt actaaagaac aagtattaaa gaattgggac tctatgctac gtgaatctat
    17461 attaagagtg tatagtgaag caggagaggc taatattaca ctatcatctg gttttgattc
    17521 aaattatata ttatatacat tagcgaatta tacgaattct tcaattaatg cattttgcat
    17581 aggaggagaa aaaggaatta atgagattcc tgaagtaact aaaattgcaa aattttatgg
    17641 tataaattta ttagttgata ctgtaatgag cccaagattt agaatatttt cccgatatag
    17701 tatggagatt ggaaggaagt ctctttgaat gtggtgtcat actgcagtac tatttaggca
    17761 ggttgttgtt ccaaaaaggg aacacaagta ttctttgtgg cgagtcagcg gatgaaataa
    17821 tgacttttaa gtatcattct gtgaactaca atcaattttg taatgataaa cagaagtcag
    17881 tatattttag ttattccgac tatccatttt atgttacaaa ttcaattgtt ttaaagaaaa
    17941 atagcctact tttgcatagt tttggcattc atcctagata tccatataaa atgtctgaga
    18001 ttgttgaaat gtctaaaaaa atatcagatc taaacgataa aaaagaattt cacaaaaaga
    18061 actgtgagtt gaggtttcaa gatagtgttc ttgataacat aaatagtgtc ccgggtacaa
    18121 ctcatttatt tagttgttta aatattcaaa cattagtaaa aattatttta tatatttttc
    18181 gatacaacag ttgtatgaaa atatttaatt ttagagataa agagcttatc ttttttaata
    18241 agattgtaaa tgggctgata caaaatattg aggagaattt agaggatgat attgaaagga
    18301 tattgaaata tttatatata tgtttattta acgaaatatt cattattaag aataaggtga
    18361 atttttttga tgatgtggaa tttaatcaga cacttagtga gtttttagat aaattgtaga
    18421 gggaatggtt atgagtgaca atactaagta tatcttttta tctccacatt tagatgacgc
    18481 aattttttcc tgtggtgatt atatttcaaa attaacttca gaaggagaaa ttgtacttgt
    18541 tattactata ttttctggtt accctttgag ccaacagcta cagccctctg ctaagcaatt
    18601 tcataagttg tgtaaccttg ggaaatatcc gattgaagaa aggaagaaag aagacaggtt
    18661 agcttgtgaa cgtctacaat gtgattttag acacttatcg tactatgaat gtctctatag
    18721 gaaagataga aatggcaatt ttctataccg tcatatctat agtaaattaa aaaatgagga
    18781 cacattaaag aatgatatca taaaagagct gttaatgcat ttagacgaca aatgtgtcgt
    18841 atattgtccg ctttcacttg gtgaccatgt tgatcatgtt tttgtgaata gtattggaag
    18901 ggcgcttgaa tttatgcgtt ataaagtaat atattatgag gacttcccat atgtaagtga
    18961 tagtagtatg gttagttata tgggaaaaac taaagaatta aaaatgtatc aagaggaact
    19021 tgatgaaaaa cattatattg atagaatatc atcaatattg tgctataaat ctcagatttt
    19081 gataatctgg aaatcagttg aaaaactttt aaacaatatt aaagagttgt atttaaggaa
    19141 tggggcagct tattctatta gattttggat taagaaataa ggaagtagtt ttatgaatat
    19201 agcagtaatt ggtttggggc atgttgggct ggcctacgcg ttactatttg catctaaata
    19261 taaagttgtt gcatatgata tagattctgt aaaaataaat aatttaaaaa agggcactct
    19321 tccatctaaa aatgaagagc ttatgaagtt tttttgcgag aataacttaa atattacttt
    19381 ttttgataca ttttctgaaa ttaaaaataa tattgattat tatattattg cgcttccgac
    19441 agattatgat gagaaaattg gtagttttaa tacatatgaa atcgaacaaa cggtatcgaa
    19501 gattctgagg gtaaaaccta atggaaagat tattttaaag tcaacagttc cgatcggctt
    19561 ttcaaacaaa ttaaaaaggc tgtttgatac aaaaaatatc atttttgtcc ctgaattttt
    19621 gagagaaggt tgttctatat atgataattt atatccaagt cgcatagttg ttggagatga
    19681 gacagttgaa ggaagaaaaa ttgcagagtt gttcctttcg attagtactc atagtactgc
    19741 caatattaaa aatgttatgt tagtttctcc tactgaagca gaagcaatta agcttttttc
    19801 taacacattc ttagctctcc gtgttgcttt ttttaatgaa ctagattctt ttgctgagag
    19861 gagaagttta aatgctgaag ttgtaataaa aggtgtttgt ttagatccaa gaattggaaa
    19921 tttttataat aatccttctt ttggatttgg aggatattgt cttcccaaag atactagaca
    19981 attaaaaaaa gaatttatag aaataaatgc cccagtgata gaagcgattg atatttcaaa
    20041 cacaaataga aaacagttca tagttaaaca aatattggaa cgaaagccaa agatagtagg
    20101 aatatataaa ttggggatga aatataattc agataattac aaagagtcag ctattttaag
    20161 tataattaat gaactattga ttgtcggtat aaaaatttta gtatatgaac caaatttaaa
    20221 cgttagtata gataacgtaa tttttgaaaa gaattttgaa ctatttataa aacaaagtga
    20281 tctaattgtt gcaaatagat gggatagggg ccttgaagct tataaagata aagtttacac
    20341 aagggggatc tggataagag attaactatt gatattaaaa aggcaataat ttataaaatt
    20401 tgtacaaaaa aatgttaaat tttcacattt tcatagtata ctgtttaata gaaagtaggt
    20461 tctttgtaac cgctccatta taaaatcctt tcactcttcc ggtatactat taggaaaaac
    20521 ataactggag gatattttga gctcacacct catcgttcca gtggctgttc cccaagctcg
    20581 tgtactgccc aaaaaagtta gacattctat ttagaacgag gattgagttc tgtattgtac
    20641 aaggctcggt ccttttagag tcagcttaag gctggctttt tcaatcacca aagtgtcaga
    20701 atgttttgac aaatgaacac aaataatgat ataatatgca aaagctagga ggtggtagga
    20761 tgattgaaaa aatggaactg ggggaatttt acaaggaatt gcgcttggcg agaaagctca
    20821 agcagtcaga tgtggcttgt gctggactaa cagcctctca gttgtccaag tttgaactag
    20881 gacagtctat gctgtctgca gacaagctga tcctagccat ccaagggatc aatatgaatt
    20941 ttgatgagtt tgggcacaaa ctcaacaact atcaagaatc tccacatatg cgaattggta
    21001 gaagggttgt ggattgcttt tcccatcagg atatagctgc tttagagcag ctattggagg
    21061 aagtcgatca agaacagatg gcgcagacct atcgtcgttt gaatgccatt gtgattaaaa
    21121 atgcactcca ttccttagat aaaagctacc cgctaacaga ggaggatagc gagtttttga
    21181 ctacctacct ctacgctatt gagtcttgga cctggtttga actctatctt ttttgcaata
    21241 ctatgccctt cttgagcaat caagatctga tctttttatc aacctcctta ctcgaaaaat
    21301 ccaaggaatt taaagagtta gtacacaatc gatggtatat gaaaagtggt tatcttaata
    21361 tcatctcaga acttatggag cgcaagctat tttcttatat tccaatcttt gaagctgagc
    21421 tggagcgcat gctccgtcca tacgatgttt ttgaaaaagt attgtggcag tttttaaaga
    21481 aaatgcagat ttttcttcaa accaaaggaa gcaatcaaaa agagattgaa cactttatcc
    21541 aatctctgca agtattagaa aatccacaat tgacagccct ttttgaattg cgtttgcagc
    21601 aatacaaaga gcttatcgat tagttagaaa tgggaaaaag ataataatat cagcaacgat
    21661 cgtcaataat gttaaaactt gtttcttcat attacttccc tcctcattag taataacttt
    21721 attataccag ggaaataatc aaatctacca aaatcgcaaa tctgaaattt ctataagaaa
    21781 aaatatcaaa tatgcgattt tctaaaataa gccaatttcc gtgttatact gtccttgtaa
    21841 aacatttgaa gcaaatccta ggtcgcagaa gtggtttaca aatgaagata attgaaggag
    21901 tgtaaaagat gttaaattta caatttgcag aaacaatgga attgacagaa gctgagttgc
    21961 aagatgttag aggaggcaac ctcgtaaatt ctatgggagg tggtggaaga agtggtatat
    22021 ctggttgggg cgtcccagga atttaccctg gttggggcaa tcaagggatg agtcctaatc
    22081 gtggagcttt tgattggact atagatttag cagatggatt gtttggccgc cgtagaagat
    22141 aggctcttat aggagataat aggatgaaga aaatgaaaga agtgaaattt cacctagcaa
    22201 ctggcttgtt gattttgact tattacctca tttttaatgt cacatcagac ttagatttta
    22261 tggttgcttt gtctgataat atgtactatg tgttccaagt tttattggta cttattctgg
    22321 gaactatagc tacaattgct tttgtcaaaa gtgaacattg gaaagagtgt ggtcgtttcc
    22381 agtttcgttg gtcttacctg ggtgttttcc ttctttcttt tttcttattg ttcgtgtggg
    22441 caaatctaac aacctatatc tttcctcgta cccagaatgg aagtacagtc gtagaagtag
    22501 ccaccagttt aacaggaatt agctattttg ttacgcgaat actttatact agtattatcg
    22561 cacctgtatc agaagaggtt gtttgtcgtg gtcttttgat gacaagttta tctaaagtta
    22621 agagatacta tcttgatgtt cttgtttccg ctgccatatt tggcgctatg catgttttgc
    22681 agtatggttg gataacgaca gatttcataa agtattttgg aatgggcttg atattttgta
    22741 tgatgtttcg ctacacccga tccatctatt gggctatagc tctgcatgct tcatggaata
    22801 gcttcttact cattgttact ttattggtat ttggatatta gaaaggtgat atatgaaaaa
    22861 gataatctca caccgctact ttattatagt ttttctacta gttattgctg accagaagtt
    22921 cagtgtttta gttttacgca gcgaccttgt tgctgggcta tctgactttg cctattatct
    22981 gtcggatatg atgttgaatt ttcttgtggt tttatttgct cttattgcta tgatttggtc
    23041 ggggaaatgg cagaaaatca atagtagaaa gtttaaagga tcctatcttt tctattcctt
    23101 cctagctctg cttgcttttg ttgcttggaa ttttgtcacc ttttttcttt tcccacctac
    23161 tcgaaatgaa atttcttatc aacatgctgc tcctactttt acaggagcta cggcattttt
    23221 gatgtatttt ttttatcctg tgattgcagg tcccattttt gaagacatga tttatcgtgg
    23281 attggtgatg acagctctgg aaaaaggaaa gaaatggggg ctagatgtac ttggttctgc
    23341 tattttattt ggggtctcgc acattagtaa tcacggttgg gtcttgacag actttttcgt
    23401 ctatatgggt ggcggactta tatttgcagt cttatttaga atgacaaagt ccatttattg
    23461 gcctattggg ctgcatatag tctacaacgg cattggtcag cttttgatgt tactgtaatt
    23521 ttggttgtta gtagtatcgc ggtctatttc tggggaaaga ttcccatttg aacttaagaa
    23581 ggagttgtga tgaaagtatt tcttcaaaat agagatttta ggcaattaac tatcaaccag
    23641 tggatttcaa cgcttgggga tacgattttt tatctggcct tcctgaatta tgtggcagat
    23701 gcgtcttttg cccctttggc gattttactt atcacgattt cagaaaccct tccccaagtt
    23761 ctacaaatct ttctgggagt tttggcggat tttcaacatc atcgtgtctt gaaatacaca
    23821 gtcattagtt ttacaaaatt tttgctttac tctatagtgt ccctatcgct ttcagggcag
    23881 tctttttcct tgttgctagt aacctttatt tgtctgctta acctcttgtc tgacacattg
    23941 agttattttt caggcgccat gctcactccg attttcatta gaattattgg gcaagaccat
    24001 ctggcagaag ctattggatt taaacagtca actgttagtt tagtgaaaac aatcagtaat
    24061 atcctaggag gagtcttact aggcattcta tccatccagt ttatttcctt actgaacgct
    24121 cttacctttt taatcgcatt tttaggtatc ctcttcataa aaactgacct cttgaaagta
    24181 gaaaaaacga ttagctatca agaaggactc tctgtaaaat ccttttgcca gcatttgctc
    24241 caatcatcga aattgatatg gaatatgaat aaggtgctct tggttttgtt tattatctct
    24301 actagtcaag cagtgataaa tgttacggtt cctatttcca ctctattttt aaggaaccag
    24361 ccctttttga atttacaaac tggtcaatct cttgccttgt tagccacact agaattatca
    24421 gcccttattt tgggaagtct gatgagtggc tatctgcaac ataccatttc cataaaaata
    24481 gccctgtatg cttcactcct actccaatta ctactcctag tgggctttgc gacagctcat
    24541 tttggcttga ttctgatctt tagctttttg gatgcctttt tcgcgggtat tctctctcct
    24601 agattgcaag aactcgtctt taaacaaata cctgaggagt caatgggagc agttcaatct
    24661 tctatcggtg ccattacggt tgttttacct agcttattta caatagcttt gggaaccatt
    24721 gctactagct ttggaactct ggcagttagc tttgttttat tactatttct tctagttgcc
    24781 tttgtcatgc ttctgaatat tcgtgaaagt atttagtgga gaatttctat aatatatgtt
    24841 tgagactgga ttgccagtct ttttatgatg gtcaaaatca acagactttt tctcttttct
    24901 gaatgtgtta tagtagactg aatctaaaat agtacgaaat aattgctaaa acatttatag
    24961 aaattaattt tactttccca atcgatttgt tctcatctta tttcaatctg ctatataata
    25021 gtccatgctg tggctggatt cttttcagcc tacttatact cttcgaaact ctcttcaaac
    25081 cacgtcagct tcaccttgcc gtaggtatgg ttactgactt cgtcagttct atccacaacc
    25141 tcaaaacagt gttttgagct gacttcgtca gttctatctg caacctcaaa acaatgtttt
    25201 gagcaacctg cggctagttt cctagtttgc tctttgattt tcattgagta ttattaagac
    25261 aatatgagga gaaagatgaa agaaaaagga ttttaggagg gggcgcaggc agccatgcca
    25321 acggctcttg gctatgtcag tatcggcctg gcctgtggga ctatcggtgc gccctatgtg
    25381 acacctgttg agatgggctt gatgagtctc tttgtttatg ctgggagtgc ccagtttgcc
    25441 atgttggcac tgattgtggt tcaagctcct gtggcagcta ttgctatgac ggtttttcta
    25501 atcaacttgc gtctcttttt gttgagttta cacgcatcga cttatttccg tcataccagt
    25561 ctttggtaca atatcggtat gtctagtatc ttgacagatg agacctatgg cgttttgatg
    25621 ggtgaattgg cccatacaga caaggtaaat cctatgtgga tgcacggaaa caatcttaac
    25681 agctatgtgg cttggtttgt ggggacagta gtcggaacgg ctctgggtgg cctgctacca
    25741 aatccagaaa tctttggctt ggattttgcc ctggttggga tgtttattgg tatttttgct
    25801 tcgcaatttc agattatgca aagacggatt cctgtccgca atctgctcat tatcctagca
    25861 gttgttgcgg tgtccttctt tttgctcttg acagtggtgt ctcagtcact agctgttctg
    25921 tttgcgacgc tacttggttg tagcatgggg gtggttttag atggtcagta agtatctttt
    25981 attagcagtt attttctctg acttggtgac ttggattctc cgtatgattc ccttcatctt
    26041 agtcaagtat aagggcttgc ctgcaatcgt tgagcgtttt ttgaagttct tgcccgtttc
    26101 cattatcttt gccttgattc tttcaagcgt agtgacaggt aaggttggga gccttcctca
    26161 aattaaatgg ctagacttct tagccgtctt tccaacagct tgggtagcct ttcgctaccg
    26221 caatctagtc ggaacagttc tctttggagt agtcttgatt gccgtcttgc gtttggtctt
    26281 ttaaatcagc cataaagaaa acctatcaca gatatatata tcatataatg gtgtaaatga
    26341 tttttttctg ttaagattat aaggtattct attttggagg aaatgacatg aaaaaaatcg
    26401 ttaaatactc atctcttgct gccctagggc ttgttgctgc aggtgtgcta gcagcttgct
    26461 ccggtggtgc taagaaagaa ggacaagcag ctagcaagaa agaaattatt gttgcaacta
    26521 attcttcacc aaaaccattc aactatgaag aaaatggcga attgactggt tacgagattg
    26581 aagtcgttcg cgctatcttt aaagactctg ataagtatga tgtcaagttt gagaagacag
    26641 agtggtcagg tgtctttgcg ggtcttgacg ctgaccgtta ccaaatggct gttaacaaca
    26701 tcagctacac taaagaacgt gcggagaaat acctttatgc agccccaact gttaaagacc
    26761 ctaacgttct tgtagtcaag aaagacgatt ctagcatcaa atcgcttgat gatgttggtg
    26821 gaaaatcaac agaagttgtt caaggaacaa catctgctaa acagttagaa gactacaaca
    26881 aacaacactc agataatcca actatcctta actatactaa agcaaactta caacaaatca
    26941 tgggccactt gagcgatggt cagtttgact acaagatttc tgataaaatc actgttgaaa
    27001 cagtcatcaa gaaccaaggt ttggacaact tgaaagtcat cgatcttcca agcgaccaac
    27061 aaccttacgt ttacccactt cttgctaaag gtcaagatga gttgaaaaca tttgtagaca
    27121 aacgtatcca agaactctac aaagacggaa ctcttgaaaa attgtctaaa caattcttcg
    27181 gagacactta cctaccggca gaagctgata ttaaataatt tcttgaaatc atccattctg
    27241 agtaagatgg gtgatttttc agttcgctac cgcaatctag tcggaacagt tctctttgga
    27301 gtggtcttga ttgccatctt gcgtttggtc ttttaaatta cccataaaaa aaacttatca
    27361 cagagataga tatcatataa tggcgtaaat gctctttttc tgttaagatt ataaggtatt
    27421 ctattttgga ggaaatgaca tgaaaaaaat cgttaaatac tcatctcttg cagcccttgc
    27481 tcttgttgct gcaggtgtgc ttgcggcttg ctcaggtggt gctaagaaag aaggacaagc
    27541 agctagcaag aaagaaatca tcgttgcaac caatggatca ccaaagccat ttatctatga
    27601 agaaaatggc gaattgactg gttatgagat tgaagtcgtt cgcgctatct ttaaagattc
    27661 tgacaaatat aatgtcaagt ttgaaaagac agaatggtca ggtgtctttg ctggtcttga
    27721 tgctgaccgt tacaatatgg ctgtcaacaa tcttagctac actaaagaac gtgcggagaa
    27781 atacctctat gccgcaccaa ttgcccaaaa tcctaatgtc cttgtagtga agaaagatga
    27841 ctctagtatc aagtctctcg atgatatcgg tggaaaatcg acggaagtcg ttcaagccac
    27901 tacatcagct aagcagttag aagcatacaa cgctgaacac acggacaacc caactatcct
    27961 taactatact aaggcagatt tccaacaaat catggtacgt ttgagcgatg gacaatttga
    28021 ctacaagatt tttgataaaa tcggtgttga aacagtgatc aagaaccaag gtttggacaa
    28081 cttgaaagtt atcgaacttc caagcgacca acaaccgtac gtttacccac ttcttgctca
    28141 gggtcaagat gagttgaaat catttgtaga caaacgcatt aaagaactct acaaagacgg
    28201 aacgcttgaa aaattgtcta aacaattctt cggagacact tatctaccgg cagaagctga
    28261 tattaaataa tttcttgaaa tcatccattc tgagtaagat gggtggtttc tcagttttta
    28321 gggatatagt tttaaactat atatctgact atctaataac aatttgtgaa atcaaacaaa
    28381 ttgtgagata ctagtacggt attattttta aggagaaaga atcatgaaaa tcaaaaaatg
    28441 gcttggccta gcagcccttg ctacagtcgc aggtttggct cttgcagctt gcggaaactc
    28501 agaaaagaaa gcagacaatg caacaacgat caaaatcgca actgttaacc gtagcggttc
    28561 tgaagaaaaa cgttgggaca aaatccaaga attggttaaa aaagacggaa ttaccttgga
    28621 atttacagag ttcacagact actcacaacc aaacaaagca actgctgatg gcgaagtaga
    28681 tttgaacgct ttccaacact ataacttctt gaacaactgg aacaaagaaa acggaaaaga
    28741 ccttgtagcg attgcagata cttacatctc tccaatccgc ctttactcag gtttgaatgg
    28801 aagtgccaac aagtacacta aagtagaaga catcccagca aacggagaaa tcgctgtacc
    28861 gaatgacgct acaaacgaaa gccgtgcgct ttacttgctt caatcagctg gcttgattaa
    28921 attggatgtt tctggaactg ctcttgcaac agttgccaac atcaaagaaa atccaaagaa
    28981 cttgaaaatc actgaattgg acgctagcca aacagctcgt tcattgtcat cagttgacgc
    29041 tgccgttgta aacaatacct tcgttacaga agcaaaattg gactacaaga aagcactttt
    29101 caaagaacaa gctgatgaaa actcaaaaca atggtacaac atcattgttg cgaaaaaaga
    29161 ttgggaaaca tcacctaagg ctgatgctat caagaaagta atcgcagctt accacacaga
    29221 tgacgtgaaa aaagttatcg aagaatcatc agatggtttg gatcaaccag tttggtaata
    29281 agaaacaggg aggtgggaga gaaaattcca cctcttgctt ttgtatagag tatagattgt
    29341 aaagaagact attcgttcat agaaaggtag agagaatatg gtttttccta gcgaacaaga
    29401 acagattgaa aaatttgaaa aggatcatgt agtccaacat tattttgagg ttttgcgtac
    29461 cttgatttct aagaaatcag tctttgccca gcaggttgga ctcaaggaag tcgcaaatta
    29521 tctgggtgag attttcaagc gtgttggagc tgaagtggag attgatgaga gctatacagc
    29581 gccctttgtc atggcacatt tcaagagttc gcgtccagat gccaagacct tgattttcta
    29641 taaccactat gacactgtgc cagcggatgg ggatcaggtc tggacagagg atccttttac
    29701 gctttcggtc cgcaatggct tcatgtatgg gcgtggggtt gatgacgaca agggtcatat
    29761 cacagctcgc ttgagtgctt tgagaaaata tatgcagcac catgatgatt tacctgtcaa
    29821 tatcagcttt atcatggagg gagcggagga atcggcttca acagacctag ataagtattt
    29881 ggaaaagcat gcagacaaac tccgtggggc ggatttgttg gtctgggaac aagggaccaa
    29941 aaatgccttg gaacagctgg aaatttctgg tggcaataag gggattgtga cctttgatgc
    30001 caaggtaaaa agcgctgatg tggatatcca ctcgagttat ggtggtgttg tggaatcagc
    30061 tccttggtat ctcctccaag ccttacagtc tcttcgtgct gcggatggcc gtatcttggt
    30121 tgaaggcttg tacgaagaag tacaagagcc caatgaacga gaaatggcct tgctagaaac
    30181 ttatggtcaa cgaaacccag aggaagttag tcggatttat ggattggagt tgcctctctt
    30241 acaggaggag cggatggcct ttctaaaacg tttctttttc gagccagcgc ttaatatcga
    30301 aggaatccag tctggttatc aaggtcaggg tgttaagact attttacctg cagaagccag
    30361 tgccaagcta gaggttcgtc tggttccggg cctagaaccg catgatgttc tggaaaaaat
    30421 tcggaaacaa ctagacaaaa atggctttga taaggtagaa ttatactata ccttgggaga
    30481 gatgagctat cgaagcgata tgagcgcacc agccattctc aatgtgatcg agttggccaa
    30541 gaaattctat ccacagggcg tttcagtctt gccgacgaca gcggggacag gacctatgca
    30601 tacggtcttt gatgccctag aggtaccaat ggttgcattt ggtctaggaa atgccaatag
    30661 ccgagaccac ggtggagatg aaaatgtgcg aatcgctgat tattacaccc atatcgaatt
    30721 agtagaggag ctgattagaa gctatgagta gagatattat caagttagat cagatcgatg
    30781 tgacttttca ccaaaagaag agaaccatca cagcggttaa ggatgtgacc attcacatcc
    30841 aagaagggga tatctacgga atcgttggat attctggagc agggaaatca acccttgtac
    30901 gggtgattaa cctcttgcaa aaaccatctg cagggaaaat taccattgac gacgatgtga
    30961 tttttgatgg taaggtcacc ttgacggcag agcagttgcg tcgtaaacgt caagatatcg
    31021 ggatgatttt ccagcatttt aacctgatga gccaaaagac agcagaggag aatgtagcct
    31081 ttgcccttaa acactctgga ctcagcaagg aagaaaagaa ggctaaagta gctaagttgt
    31141 tggacttggt tggtttggca gatcgtgctg aaaactaccc ttcacaacta tctggagggc
    31201 aaaaacagcg tgtggcaatt gcgcgtgcct tggccaatga tccaaaaatc ttgatttcag
    31261 acgagtcaac ttctgccctt gatccgaaga caaccaagca gattttggcc ttgttgcaag
    31321 atttgaacca aaaattaggc ttgactgttg tcttgattac gcatgaaatg cagattgtca
    31381 aagacattgc caaccgtgtt gcagttatgc aggatgggca tttgattgaa gagggtagtg
    31441 tgcttgaaat cttctcaaat cctaaacaac ctttgactca agactttatc tcaacagcta
    31501 caggtattga cgaagccatg gtcaaaatcg agaagcaaga aatcgtggaa cacttgtctg
    31561 aaaacagtct cttggtgcaa ctcaagtacg ctggagcttc aacagacgag ccacttttga
    31621 atgaattgta caagcattac caagtaatgg ctaatattct ctatgggaat atcgaaattc
    31681 tcgatggtac tcctgttgga gaattggtgg tggtcttgtc aggtgaaaaa gcagcgttgg
    31741 caggtgccca agaagccatt cgtcaagcag gtgtacaact aaaagtattg aagggaggac
    31801 agtaagatgg aatcattgat tcaaacctat ttaccaaatg tctataaaat gggttgggct
    31861 ggtcaggcag gctggggaac ggctatctac ttaactcttt atatgacagt tctttccttc
    31921 attatcggag gcttcttggg gctagtggca ggtctctttc tcgtcttgac agcgccaggt
    31981 ggtgtcttgg agaataaagt cgtattctgg attttagaca aaattacctc aatttttcgt
    32041 gcagttccct ttatcatcct cttggcaatc ttgtcaccac tttctcactt gattgttaaa
    32101 acaagtatcg ggccaaatgc agcccttgtc ccactttctt ttgcagtctt tgccttcttt
    32161 gcccgtcagg tgcaggttgt cttggctgaa ttggatggcg gtgtcattga ggcggctcaa
    32221 gcgagcggag cgactttctg ggacatcgtg ggtgtttacc tatcagaagg tcttccagat
    32281 ttgatccgtg tgacgactgt gaccttgatt tcccttgttg gggaaacagc tatggccggt
    32341 gcggttggag ctggtggtat cggtaacgta gccatcgctt atggatttaa ccgctacaat
    32401 cacgatgtga ccatcttggc aaccatcatt atcattttga ttatctttgc aatccaattc
    32461 ttgggagatt tcttgactaa gaaattgagc cataaataaa aaagagccgc gtggctcttt
    32521 ttaactgatc agattttctg tgcaaatttt ttactcaagg cttgtccaat caaggcaccc
    32581 actagggctc cgatgacaat acttgcgata aatagaagga cagttccagg gtttggagcg
    32641 accatgatgc ggtcgatata ttcttgggat tttcctcttg ccagaagagt agccatatag
    32701 gctttgggcg caatccacat aagcaagatt ggtcctgttg tactaaaggc gaaaataatg
    32761 aaagaaagga agttctttgt tttgtccttg tattttccta aatgagctac tccatctgct
    32821 aggaggccac agataattcc aggaaggaag gaaccagcac cgtgtttagt tcccaagaaa
    32881 aagagggcaa tgacaaggcc gatagtggta atggctccaa agcgcggaac ttttgcgact
    32941 aggatcatat agacgctacc gccgacaagg gcagtaaagg caggcgcata aaacatgttt
    33001 ccagtttggt caaagagatt gcccaaaagg acaccaatcc ccatgcagag gaagtaaaga
    33061 actgcaaaaa gcagtgtagt taagatagat ttcttcatga attgtctcct gataattttt
    33121 tcacaattct cattttacca tggtttggtg ggattgtaaa tggatactag aagtttttga
    33181 aaacgcttga aatatgatat aatggtttca tagttatttt taggggaata tcatgggtag
    33241 atttttagac tttgtcttta atcgtttctt tttagggatg attgcgacag ccttcttttg
    33301 gctattaact ttagcaggag ggattatcct tggtctagcg ccggctagtg ccaccttgat
    33361 gagcttatat gcagaacatg gttatagctt tcgggaatac agtttgaagg aggcttggtc
    33421 tctttacaag caaaattttg tctcaagcaa cctgattttc tatagctttt taggtgtggg
    33481 tctagttttg acctatggtt tgtatctctt ggtgcaattg cctcatcaga ctattgttca
    33541 tttgattgcg acccttttga atgtcctagt agttgccctg atctttttgg cttatacagt
    33601 atctttaaaa ttacaagttt attttgcctt gtcctatcga aatagtctca aattatcctt
    33661 gattggcatc tttatgagtc tagcagctgt ggccaaggtt ctccttggga ctgtgctact
    33721 tgtagcaatt ggttactata tgcctgccct gctatttttt gtaggaattg ggatgtggca
    33781 tttctttatc agtgatatgt tggaacctgt ctatgaaatc atccatgaaa aattggcgac
    33841 aaaatagaat gaagcagttt tggctacata cgcttctaag aacctatagt tcagtgatga
    33901 tcattatcat tgcgagtttt gcaatcttac tctcttacgc tgactgggat tcacgtgaaa
    33961 aggaagccca gagagtagcc cagcgtgtaa ctgctagaac agtgagtgaa attgaatatt
    34021 accatagaga gtcaacccag atagctcagg ctttagttga aaatcaagct cgtattgagg
    34081 gaatctataa atactttagc cttagcatgc cagactattt ttactggcaa ttagagcgga
    34141 aagcttcgcc ttatatatca gtctctctgt atgaaaatgt tgatgacctc tatgttcgaa
    34201 atgattttgt aactggggtg gccattgctt ttcaagatta caaggaagtc tatgtttcta
    34261 ctaaagacaa acgtagtgga gaaaaaatca gggctgagga tttcaaacca gcaggaaata
    34321 gttttgccat tccggtgtca gatccagtgt cagatcaaga tttaggagtg atttacatct
    34381 ccttggatcc tgctgtttta taccatgcca ttgataatac tagaggtcat actccgatgg
    34441 cagtaacagt gacctcacct tttgatacgg agatttttca tattggtgag acagttgata
    34501 gggagagtga aaattggcta gttggcttaa cttctcatgg atatcaggtt caggtggcag
    34561 ttcctaaaaa ctttgtttta caaggaacag tgactagctc tgctttgatt gtgggtttga
    34621 gccttctctt tattgtcatt ctttatctga ctttgaggca gacttttgct aattaccaaa
    34681 agcaggtagt ggatttagtg gaatccattc aagtcattgc tcaaggcgaa gaggggcgtc
    34741 ggattgacat ttccgaaaaa gatcaggaat tactcctaat cgcggagacg accaatgata
    34801 tgttggatcg attggaaaag aatatccatg atatttacca gttagagctt agtcaaaaag
    34861 atgccaatat gcgagccttg caggcgcaaa tcaatcctca ttttatgtat aatacgctgg
    34921 agttcttgcg catgtatgca gttatgcaga gtcaagatga gttggcagat atcatttatg
    34981 aattcagtag tctcttgcgt aacaatattt ccgacgaaag agagaccctc ctcaaacagg
    35041 aattagaatt ttgccgtaaa tacagctatc tctgcatggt tcgctatccc aagtccattg
    35101 cctatggttt caagatagat ccagagttag agaatatgaa gattcccaag tttaccttgc
    35161 aaccgctggt agaaaactat ttcgcgcatg gtgttgacca caggcggaca gataatgtga
    35221 ttagcatcaa ggctcttaaa caggatggtt ttgtggaaat tttggtggtc gataatggta
    35281 gaggaatgtc ggctgaaaag ttggcaaata tccgagaaaa attaagtcag aaatattttg
    35341 aacaccgagc cagctacagt gatcaaaggc agtctatcgg gattgtcaat gtacacgagc
    35401 gttttgtgct ctattttgga gaccgctatg ccattacgat agagtctgca gagcaagccg
    35461 gtgttcagta tcgtattaca attcaagatg agtagaaagg gagaaaatgt ataaagtatt
    35521 attagtagat gatgagtaca tggtgacaga aggtctgaag cgtttgattc cctttgataa
    35581 gtgggatatg gaggtcgtcg caacagccag tcatgccgat gaagctctag aatatgttca
    35641 ggaaaatcct gtcgatgtca tcatttccga tgtcaatatg ccagacaaaa cagggcttga
    35701 tatgattcgg gagatgaaag agatcttacc agatgctgcc tatatcctgc tctcaggtta
    35761 tcaggagttt gattatgtaa aaagagcaat gaaccttagt gtggtggact atttggtcaa
    35821 gcctgttgat aaggtagagc tgggaaatct gctggagaag attgcaggtc agctcggcga
    35881 gagagggaag aaaagtcaga ctcttagtca agaattagac gaggctggat ttgttagtta
    35941 tttaggggat aaggagaatt ggtggatagg tctatccaag gaaaaacaag gttccttcac
    36001 cattccctac tatgtcttgg gccaagactg gcagattttc atttctgacc aacccctaga
    36061 tggtttagtc gttacacctt ttgaagctcc ttatcaagaa cactttgaac gctggaagct
    36121 gaatgctgag aaaaccctct tttacggttc tgtaaatttg cagcagtctg agagtctctt
    36181 tgcctattac gaaccgattt atagggttat cattcaggga aatctcaatc aaatcgtaga
    36241 agagttaaat ctcttggaga aggtagttct tgaaaatacg ccgcgtgttc cgattactaa
    36301 acagcttttt attcagtttg tcatggatgt tttccattta tttgaacatc tcaaagctga
    36361 tgacctgaca gacatcgtca aaaccattca tgctattcaa tccttcgatg aattggttcc
    36421 ttatatcaag gaaactctga gcagcttttt cggtcaatac cgtatgaatg aaaatgtggt
    36481 cagtgtgctg gaagtcattg gttgtgatta ccaaaaagag ctttccctca aggatatcag
    36541 taaggctctc tttatcaatc ctgtctatct agggcagttg attaagcgtg aaaccgattc
    36601 gacttttgca gagttactaa acaaacaacg tattaaggct gcccaacaac ttttgctttc
    36661 aactagtgac agcatcgaag atatttgtta tgctgttggt tacagtaacc ttggatattt
    36721 ctataaagtt ttccgaaaat tgtgcggaaa atcgccaaaa gcctaccgaa aacaggtaga
    36781 aactatacta taagatttgt attcctttac aaaatgtgct ataatataaa tattattatt
    36841 aggaggttct atcatgaaaa agaaaccaat ttatctatgg gtcttgctaa tcttgtctgc
    36901 ccttatttca gttccgtctc tgtttggaat tgtgagtccc ttgcctagta aagaagccct
    36961 tcgtactgct cagaaacaag ttgcaggggt caatgctcag caattagaag accagcttaa
    37021 ttatacctat agagtagcag aagcatctca ttctattttt aatgttgctt tgattgtgct
    37081 atctactatt ttagtggtcg tagcgattgt cttccttgtt cgtaaaaatt tgcaatatgc
    37141 aaactatact tacgttggct atgttttgtt agctattatt ggttcgattt atggctatgt
    37201 tggtttacaa gacgctgtgc agttggttca agatgagagc atgcgtttga cagtgagtat
    37261 tggttcaaaa gctgttagca ttttctatat cgtcatcaat gttctcttcc tagcccttgt
    37321 cttctataag atgtggcgac aacagaaagc ctcggcagaa gaagaggaaa cagaagagct
    37381 tgcctaagta ttgacaaaaa agaactatca agatacaatc ttggtagttg ttttttgatt
    37441 atagataaaa tcatggaggt acatatgaag ataatttctt tagtttatat tagtttgagt
    37501 ggcaacactg aaagttttgt gacgcgcttg aaagactatc tcttgtccca gtacaaaggg
    37561 attgaggttc aaaagattca tatcaaggat ttagtcaagg aaggcaaaaa tttctatgaa
    37621 atggaccatc cctatgtcgc ttttttgccg acctatctcg aaggtgggaa tggcgtggat
    37681 aacggagatg ttgagatttt gacgacaccg gtgggagatt ttattgccta tggtaacaat
    37741 gctagtaagt gttttggtgt ggttgggtca ggaaatcgta actttaataa ccaatactgc
    37801 ctaacagcca agcaatacag tcaacgcttt ggctttcctg tattggctga ctttgaaatg
    37861 cgaggcatgc tggaagatat caaacatgtc gcagctatta tcgcagattt gtatgagttg
    37921 gaaaaggaga attaatactc aatgaaaatc aaagagcaaa ctaggaagct agtcgcaggt
    37981 tgctcaaagc acagctttga ggttgcagat agagctgacg tggtttgaag agattctcga
    38041 atagtataaa attcttataa gaggtggttg aagttgttca actgtttttt gagtataaac
    38101 agtctttaag aacgtaaaaa agcataagtt caggtcttca aaaccttgtt cttatgcttt
    38161 ttatcataga aatatttgct gaattttctc ttgaaatgaa accttatctt catctcgcgc
    38221 ttgtccctta ccctgctttt ccgattgcga gtgcgtagat aaagaagatg gcgaagccaa
    38281 agaggaaaat caatcccgca atggcaaggt gtttgagcca agaaggaaga tttttgtttt
    38341 cacgcgttac caaggcgtaa ttcaaaagag caaagaaagg tgttgtcagg aaagagccaa
    38401 tcatggcaaa gcggagcatg gttgaaacct gaccagagaa gaacttgata atgacgatac
    38461 cgatgatagc agtgatggtc atccagatgt tcaaagattt acgattgtcc tctttttgac
    38521 tgattagcag tcggagagat tcctgattaa cgcgagaata gccatcgata acagttataa
    38581 ctgttccaaa gatacagagg aaggcaataa aggtaatcaa gtaacgggac cattcgccaa
    38641 gaacagaggc atacatgccc acgaattgag agatgtattt ggctgaagca gcttcaaccg
    38701 cctgccctgt aggatactga atcagtgctc ccagtgccac aaagaagacg gctaggatag
    38761 ctgttccaat ataaccagtg ttaaagtcaa acagagcgtc ttctgtgtta aagttgacgg
    38821 tctttctctt ttcagctgac caaagtgaat tgatggctga aatttcaata ggagccggca
    38881 tccatcctag gagggagacg atgaagggca gagctgccat ttgccaaggt gtcttctcga
    38941 caaaatcaga actgtattct ggatgcttga ccgccgcaat gataactgcc agaacagtcg
    39001 caatggttaa ggcagacata atccatttga ccatgccgtc taaaagtttg tagcctccaa
    39061 agagtagcat agcccaaatg attgcaacga gaatgaggga ccactgagta atgctaagtc
    39121 caatcattgg gaaggcactg gcgatgatag ctgagcacag aatggcaaca ccagccgtgt
    39181 tgaccatagc cgaaaagaca ttgaggataa agaaaatcca gagatagagt tttccttttt
    39241 cggcataacc ttcaaccaaa gtctttccag tatcagctgt gtattcagca ccaaaacgga
    39301 aaaatggata tttaaagaca ttggctaaga tgaccaagag aagtagagac caaccgtaag
    39361 aaccgccagc ttgagttgag gatacaatgt gggaacctcc aacagcggca gttgccatta
    39421 ggattccagg tcccattgct tttagcttgc ttgcccaggt tgattgattt aaggaaatag
    39481 cttgcgacat gataaatact cctttttgaa ttttcagaat aatctgtata tgtaatctat
    39541 attctacaaa aaattttgga aaaatgcaag aatattttga aaaaagatag aaaatttaca
    39601 aagaaaat
//
LOCUS       DAVBCA010000014        37748 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.014, whole genome shotgun sequence.
ACCESSION   DAVBCA010000014 DAVBCA010000000
VERSION     DAVBCA010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37748)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37748)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37748
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.014"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..139
                     /locus_tag="VQU19_000664"
     CDS             <1..139
                     /locus_tag="VQU19_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2479944.1"
                     /translation="RSKVENIFAKVKTFKMFSTTYRNHRKRFGLRMNLIAGIINHELG
                     F"
     gene            207..455
                     /locus_tag="VQU19_000665"
     CDS             207..455
                     /locus_tag="VQU19_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2479945.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRIYSGNLILQELITVNGAYKATYIGELSSN"
     gene            586..1758
                     /locus_tag="VQU19_000666"
     CDS             586..1758
                     /locus_tag="VQU19_000666"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HET2479946.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENADSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            1758..3032
                     /locus_tag="VQU19_000667"
     CDS             1758..3032
                     /locus_tag="VQU19_000667"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HET2479947.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLEFANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLIGILSNYATDSL
                     VTASCRMAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VAFSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(3068..4033)
                     /locus_tag="VQU19_000668"
     CDS             complement(3068..4033)
                     /locus_tag="VQU19_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET2479948.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQTIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(4014..5468)
                     /locus_tag="VQU19_000669"
     CDS             complement(4014..5468)
                     /locus_tag="VQU19_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HET2479949.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFKETGIKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKSQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEHPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            5845..7728
                     /locus_tag="VQU19_000670"
     CDS             5845..7728
                     /locus_tag="VQU19_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET2479950.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYALADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     AQGNKVKAGDVLGTFDSNKIAAAGLDDTTMVIVTNTADYASVAPVATGSVSKGDAVIE
                     VKI"
     gene            7877..8764
                     /locus_tag="VQU19_000671"
     CDS             7877..8764
                     /locus_tag="VQU19_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET2479951.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEMVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGTSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(9084..9701)
                     /locus_tag="VQU19_000672"
     CDS             complement(9084..9701)
                     /locus_tag="VQU19_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HET2479952.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(10116..10304)
                     /locus_tag="VQU19_000673"
                     /pseudo
     CDS             complement(10116..10304)
                     /locus_tag="VQU19_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(10814..10894)
                     /locus_tag="VQU19_000674"
                     /pseudo
     CDS             complement(10814..10894)
                     /locus_tag="VQU19_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            11010..11903
                     /locus_tag="VQU19_000675"
     CDS             11010..11903
                     /locus_tag="VQU19_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2479953.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            11900..13099
                     /locus_tag="VQU19_000676"
     CDS             11900..13099
                     /locus_tag="VQU19_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2479954.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLEQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAGGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(13452..14219)
                     /locus_tag="VQU19_000677"
     CDS             complement(13452..14219)
                     /locus_tag="VQU19_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2479955.1"
                     /translation="MFWNLVHYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(14236..14931)
                     /locus_tag="VQU19_000678"
     CDS             complement(14236..14931)
                     /locus_tag="VQU19_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2479956.1"
                     /translation="MSLLVFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            complement(14936..15301)
                     /locus_tag="VQU19_000679"
     CDS             complement(14936..15301)
                     /locus_tag="VQU19_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET2479957.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMIH
                     FGYEKEELPGVVSDYIKGV"
     gene            15441..15914
                     /gene="nrdR"
                     /locus_tag="VQU19_000680"
     CDS             15441..15914
                     /gene="nrdR"
                     /locus_tag="VQU19_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HET2479958.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            15915..17084
                     /locus_tag="VQU19_000681"
     CDS             15915..17084
                     /locus_tag="VQU19_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HET2479959.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLEHPVYRRLLEKKIGDSAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFNPKEATIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEEAVLRIRER
                     GQKTKTQKQNQTAPAKTNIPKWSNPDYKNETSEETRLELERKKQELLARLEKGGD"
     gene            17085..17981
                     /gene="dnaI"
                     /locus_tag="VQU19_000682"
     CDS             17085..17981
                     /gene="dnaI"
                     /locus_tag="VQU19_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HET2479960.1"
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTAWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            17978..18691
                     /locus_tag="VQU19_000683"
     CDS             17978..18691
                     /locus_tag="VQU19_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HET2479961.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            18705..20015
                     /gene="der"
                     /locus_tag="VQU19_000684"
     CDS             18705..20015
                     /gene="der"
                     /locus_tag="VQU19_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HET2479962.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            20106..20441
                     /locus_tag="VQU19_000685"
     CDS             20106..20441
                     /locus_tag="VQU19_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2479963.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            20581..20916
                     /locus_tag="VQU19_000686"
     CDS             20581..20916
                     /locus_tag="VQU19_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2479964.1"
                     /translation="MEYLFKMIILLPCFYFFSWIEKANRDSKIFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLDYICFKKMLDLRRE
                     LGKSKGGRH"
     gene            21101..21892
                     /locus_tag="VQU19_000687"
     CDS             21101..21892
                     /locus_tag="VQU19_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2479965.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAIITYFFGTFSPLEWNSLFSDGSGLQR
                     LLDGEIKSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYVVPYMVLKKYEDNV"
     gene            21885..22526
                     /locus_tag="VQU19_000688"
     CDS             21885..22526
                     /locus_tag="VQU19_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2479966.1"
                     /translation="MFKNFNNIWLKRKIVLLLRIVLMMILINYLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLFVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLVLLSLLVMLIVSRLEEKFKKG"
     gene            22530..23180
                     /locus_tag="VQU19_000689"
     CDS             22530..23180
                     /locus_tag="VQU19_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2479967.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKILAGYIKLDKGKVLQDGKVYGVKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQYVKDIQS"
     gene            23191..23478
                     /locus_tag="VQU19_000690"
     CDS             23191..23478
                     /locus_tag="VQU19_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2479968.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLSFFFIPWDRAILGVRIDIFI
                     MQKILLAFGILSILMALLSKKVSLFVFGLICCLSLWINLFITFAILPIFGN"
     gene            23624..26137
                     /gene="secA"
                     /locus_tag="VQU19_000691"
     CDS             23624..26137
                     /gene="secA"
                     /locus_tag="VQU19_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HET2479969.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMATLTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDVITADRDL
                     APEIQAMIKRTIERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            26218..27249
                     /locus_tag="VQU19_000692"
     CDS             26218..27249
                     /locus_tag="VQU19_000692"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HET2479970.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            27251..28282
                     /locus_tag="VQU19_000693"
     CDS             27251..28282
                     /locus_tag="VQU19_000693"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HET2479971.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            28321..28689
                     /locus_tag="VQU19_000694"
     CDS             28321..28689
                     /locus_tag="VQU19_000694"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HET2479972.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            28679..29782
                     /locus_tag="VQU19_000695"
     CDS             28679..29782
                     /locus_tag="VQU19_000695"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HET2479973.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVRVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLALPYDLIPALTLESALVHIKTVPAGACMGYGATYQTDSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKPYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            29801..31816
                     /gene="recG"
                     /locus_tag="VQU19_000696"
     CDS             29801..31816
                     /gene="recG"
                     /locus_tag="VQU19_000696"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HET2479974.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     IKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQMLKSENRVQGSGLVLNWSQEKVTAVKVSLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            32132..33112
                     /locus_tag="VQU19_000697"
     CDS             32132..33112
                     /locus_tag="VQU19_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HET2479975.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAMEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
     gene            33917..34144
                     /locus_tag="VQU19_000698"
     CDS             33917..34144
                     /locus_tag="VQU19_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2479976.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            34432..37329
                     /gene="nanA"
                     /locus_tag="VQU19_000699"
     CDS             34432..37329
                     /gene="nanA"
                     /locus_tag="VQU19_000699"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HET2479977.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAE
                     LPNGRVRLYVNGVLSRTSLKSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGNRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKKIDGKTYQILY
                     REGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGNQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NRRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHNGKEYIILSNAGGPNRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWEFLSKDLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKG
                     SIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLV
                     TLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
BASE COUNT        11302 a         7031 c         8404 g        11011 t
ORIGIN      
        1 gagaagcaag gttgagaaca tctttgccaa agtaaaaacg tttaaaatgt tttcaacaac
       61 ctatcgaaat catcgtaaac gcttcggatt acgaatgaat ttgattgctg gcattatcaa
      121 tcatgaacta ggattctagt tttgcaggaa gtctactact ttccttattg tctgtaaatc
      181 tactgacctt gttgtttatc ccagtcatgg tttctagttc gggctcagag tttcaaagtg
      241 gatggcaaga gcatcaattg attgctgaga aggttagtaa aacacttgat aagacatttg
      301 ataaggatgt cagagaaatt ccgaccagtc agttttatca aaaatttgta gatgagatgg
      361 gaaggattta ctcaggaaat ttgatcctcc aggagctgat aactgtgaat ggagcttata
      421 aagctactta tatcggtgaa ctctctagca actaatcatt ctttaaaatg atgaccaata
      481 agaggcttga tttggtgaat caagtctttt ttctctcttt tactgccatt tgtgataaaa
      541 tagtatagaa cgatttttta catgaatgat aaaacagagg taaatatgac aatcggtatt
      601 gataagattg gttttgcgac cagtcaatat gtcttgaaat tacaagactt agcagaagcg
      661 aggggaattg accctgaaaa attaagtaaa ggactcttac tcaaggaatt gagtattgcg
      721 cccctaactg aggacatcgt gaccttggcg gccagtgcta gtgactctat tttaactgag
      781 caagaaagac aagaagttga catggtcatt gtggctaccg agtcaggaat tgaccagagt
      841 aaggctgcgg ccgtctttgt gcatggcttg ctgggcatcc agccctttgc tcgtagtttc
      901 gagattaaag aagcctgcta tggggcgaca gctgccctcc attatgccaa attgcatgtg
      961 gaaaattctc cggagtccaa ggtcttggtc attgccagtg atattgccaa atatggtatt
     1021 gaaactccgg gagaaccaac tcaaggtgct ggaagtgtag ctatgttgat tacacaaaat
     1081 ccacgcatga tggcctttaa taatgacaat gtagctcaga cccgtgacat catggatttc
     1141 tggcgaccaa attactcgac aactccttat gtaaatggtg tctattctac ccaacaatac
     1201 ttggatagtt tgaaaacgac ttggcttgaa tatcaaaaac gctaccagct tactctggat
     1261 gattttgcgg ctgtttgttt ccacttgcct tatcctaaat tagcgctaaa aggcttgaaa
     1321 aaaatcatgg ataagagcct gcctcaagag aaaaaagacc tcttacaaaa gcattttgac
     1381 cagtctattc tctacagtca aaaggtgggg aatatctaca caggttcact tttccttgga
     1441 cttttgtctc tcttggaaaa tgcagatagc ttgaaagctg gggataaaat cgccctttat
     1501 agttacggaa gtggagctgt ggctgagttc ttcagtggtg aattggttga aggatatgaa
     1561 gcttatttgg ataaagaccg cttgaacaag ctcaaccaac gaactgcctt atccgttgca
     1621 gactatgaaa aggtcttttt tgaggaagta aacttggatg aaacaaactc tgcccagttt
     1681 gctggctatg aaaatcaaga ttttgccttg gttgaaattc tcgaccacca acgccgttat
     1741 agcaaggttg aaaaataatg aagataagtt ggaatggatt ttctaaaaaa tcataccaag
     1801 agcgcctcga gctgttaaaa gctcaggcgc tccttagtcc tgagagacaa gctagtctgg
     1861 agaaggatga acagatgagt gtgactgtgg cagaccagct gagtgagaat gtagtgggaa
     1921 ctttttctct gccttattcg ctggttccgg aggtacttgt caacggtcag gaatacaccg
     1981 ttccctatgt gacagaagaa ccctctgtgg ttgcggcggc cagctatgcc agcaaaatca
     2041 tcaagcgtgc aggtggtttt actgcacaag tccatcagcg ccagatgatt gggcaggtag
     2101 ccctttatca agttgctaat cctaaactag cgcaagagaa gattgccagc aagaaagcgg
     2161 agctcttgga gtttgccaat caagcctatc cttctatcgt taaacgtgga ggtggggcgc
     2221 gtgatctgca tgtcgagcag ataaaaggcg aaccagactt tctcgttgtt tatattcatg
     2281 tcgataccca ggaagccatg ggtgccaata tgctcaacac catgctggaa gccttgaaac
     2341 cagtcttaga agaactcagt cagggacaga gtctcatagg aatcctgtcc aactacgcga
     2401 ccgattctct ggtgactgca agctgtcgca tggcctttcg ctacttgagc cgccaaaagg
     2461 atcaaggacg agagattgcg gagaaaattg cgttggctag tcagtttgcg caggctgatc
     2521 cttaccgagc tgctactcat aataaaggaa tttttaatgg tattgatgcg attttgattg
     2581 ccactggtaa tgactggcgt gccatcgaag ctggggccca tgcctttgcc agtcgagatg
     2641 gacgctatca aggtcttagt tgctggacgc tggaccttga aagagaagaa ttggtcggtg
     2701 agatgaccct gcccatgcct gtagcgacta agggtggctc tatcggcctc aacccacgtg
     2761 tagctttcag tcatgatcta ctaggaaatc cttctgccag agaattagcc cagattatcg
     2821 tgtccatcgg tcttgcccaa aattttgcag ccctcaaagc tttggtaagt acgggcatcc
     2881 agcaaggcca catgaaacta caggccaaat ccctagctct cctagctggg gctagtgaat
     2941 ctgaagttgc tcccctagta gagcgcctca tctcagataa aacctttaac ctagagacag
     3001 cccagcgcta tctcgaaaat ttaagatcat aaaaaactca gacgaatcgg tctgagtttt
     3061 cttgtgttta aatacttttt cctggtaata gtgtaactgg taagaagtaa ccagttgtgg
     3121 caacttcctt gccttcaatc ttttgcaaga gaagatcaat agtgagacaa gcaatctctt
     3181 ccaaaggttg cttgatagta gccaattgag ggtagtaatt ttcgataaag taggtcccat
     3241 catagccgat gaccttgagc tcttttggga cagaaatgcc caattcttga gcgattttaa
     3301 tgaccagaat agctgtcaaa tcatccgaag caaaaatggc atctggtttt tcccgggtca
     3361 agatattctt gatttccatt tcttttctga cgggagaaaa gtcactggaa acattgataa
     3421 taggagcttt tgggagtacg gatgcaaaac cagcgtggcg tagtccggtt ggcgaattgg
     3481 aattgtcatt ccctgtaatc atgatgatag tctgggcacc tgtcttgacc aaggtttggg
     3541 cagcaagaac cccaccagca tagttgtcag aggagacgac agggatgtct ggcgataggt
     3601 ttcggtcaaa ggaaataatc ggcgctgtca cacgattgta gtcttcgatt cctaggttgt
     3661 gactaccaga aatgatgccg tccacctgat tggcttccaa catttcgatg tattcgcgtt
     3721 ccttctcaga atcatgttca ctgttgcaga tgatggtctt gtaaccattt ttgaagagtt
     3781 ggtgttccaa tttatcaatc aattctgcat agaaaacatt ggaaatatta gggaaaatca
     3841 agccgattaa cttagctgat tttccttgca gactacgagc caggttgttg ggtttatagc
     3901 ccaattctcg catggcttca ttgacttttt ggatggtttt ctcagataga tacccttttt
     3961 tattgataac ccgagaaacg gtagtaggac tgacgcctgc aagtttggcg acatcagtta
     4021 gttttgcgac cataatctaa ttcatagtaa gttccagttg ggtttccaga tttgatcagg
     4081 ataccatttt ggtccgcatg tgggaagaca cgaccagaaa atactttttc tcctttattg
     4141 atgaaaattt caaagacaga gttatcgatg aagattgtag cagtagtagc ctgattctcg
     4201 atagggcaag aacgagttgt cccaaattct tgggcatact gttctccagc ctggctacga
     4261 tccactgtca cttgaccgtt tacaaggtca aagttgattg aaagtccctt accttcttta
     4321 tcagcaagta agacaatctc gctctggcta ttagcttcca agttgagttc aagttcgtaa
     4381 gtgttcttgg tttgggaacg gtttgagaag gcttcttcag aagcacgaag gtccttaata
     4441 gcagcgactg gatactggta gagcttgtcg tctttgatag tgagttcctt gaccaaagag
     4501 aaggttcctt ggtggtcaaa acggtcagat gggtaagaaa catctggcaa accaagccag
     4561 ctaactgcta gagcacgccc atcaggagcg ttgaaggctt gagttgcata ggcttcgaaa
     4621 ccgtaatcca tgttttgaag ttgagacaca tctaccattt tggcattttt agggtcaaag
     4681 gaagccccaa tcttatacat atttggaaag atattatcgt agtctagaac tttcttatcc
     4741 aatccttgtg gacagtagag aaggacagga tgttcctcta caaagaccag attaggacat
     4801 tccatcatgt aggcagtacg gtcgttagca aagtcaaggt cgccaactgc ttgccagttt
     4861 gtgtagtcgt tattgacagc cttgtagaga cggacgaagc cttttttctc caagtcctgt
     4921 ccaccgacga cagcatagta ttgactttta aagttaaaaa tttgtggatc gcggaagtgg
     4981 tcagtagagt ctgctggctg gtcaatcaag atcttgtcaa tctttgtaat cttaccctcc
     5041 ttgtccatca aagcaccgat ctggtatggg tgacggatcc agttttcatc gcgaacattt
     5101 cctgtataaa ataggaataa gttatcgcca aattgcatgg cagaaccaga gtaggcaccg
     5161 tggctatcta atggagtatc tggtaaaact ttgattccag tttctttaaa gtgaaccaaa
     5221 tcatcacttt ctagctgtgc ccaagatttc aaaccgtggg ctgcaccaaa aggaaaattc
     5281 tggtaaaaga ggatccactt gccatcaaag taagaaaagc catttgggtc gttgagaagt
     5341 cctgtttttg gctcaacatg gtaatgagta tgccatggag attgtgccat attttccttt
     5401 atatgttgaa tttcttcttg cgtccaatct tgataaagtc tgtaacgacg ctcagttgtc
     5461 cattccattc attcctccaa aaatcttatc acttttaata gtaactgttt tcgataaaaa
     5521 atgcaagcct tttatgttaa aaaagaggaa aaactgtcaa acgattatca taaaataaat
     5581 acaggaaatc aatcaaattt ttacgaaaat gtgaaagata atgaaataaa agacttttta
     5641 accaaggttt caaacttatt tttcaaggaa ttcctgatga aacagtcaaa aacaatcaat
     5701 ctaaaacttg cccactaagt ggatagaata ttttttctgc aaaacgcttg acatattttt
     5761 aaaacatgat aaaataatag tcgtaagggc gaataaaatc gctttcaaac aagaacaaaa
     5821 tgttatataa ggagattttt gcaaatgaac aatcaggaaa ttgcaaaaaa agtcatcgat
     5881 gccttgggcg gacgtgaaaa tgtcaatagt gttgcccact gtgcgactcg tctacgtgtc
     5941 atggtcaaag atgaagagaa aatcaataaa gaagtgattg agaacttgga aaaagttcaa
     6001 ggtgctttct ttaactcagg gcaataccaa attatctttg gtacaggtac agttaacaaa
     6061 atgtacgatg aagttgttgt acttggctta ccaacatcat ctaaggatga catgaaagca
     6121 gaagttgcta aacaagggaa ctggttccaa cgtgctatcc gtactttcgg tgatgttttc
     6181 gttccaatca tcccagttat cgtagcgaca ggtctcttca tgggtgtgcg tggtcttttc
     6241 aacgctcttg aaatgccact tccaggtgac tttgcaactt acacacaaat cttgacagat
     6301 acagccttca tcatcttgcc aggtttggtt gtgtggtcaa ccttccgtgt atttggtgga
     6361 aatcctgccg ttggtatcgt tcttggtatg atgcttgtct ctggctcact tccaaacgct
     6421 tgggcagttg ctcaaggtgg tgaagtaaca gcgatgaact tctttggttt catccctgtt
     6481 gttggtttgc aaggttccgt tcttccagcc ttcatcatcg gggttgtcgg agctaaattt
     6541 gaaaaagctg tccgcaaggt tgttccagat gtcattgacc tcttggtaac accattcgtg
     6601 acacttttgg tcatgtctat ccttggactc tttgtcattg gaccagtttt ccacgttgtt
     6661 gaaaactaca tccttattgc tacaaaagcg attcttagca tgccatttgg tcttggtggt
     6721 ttcttgattg gtggggttca ccaattgatc gtcgtgtcag gtgtgcacca catcttcaac
     6781 ttgcttgaag tgcaattact tgctgctgac catgctaacc cattcaacgc tatcatcaca
     6841 gctgctatga cagctcaagg tgctgctact gttgcggttg gtgttaaaac aaaaaatcca
     6901 aaactgaaaa cacttgcttt cccggctgct ctttctgcct tcctaggtat tacagagcct
     6961 gctatcttcg gggtgaactt gcgcttccgt aaaccattct tcctttcatt gattgctggt
     7021 gcaatcggtg gtggattggc ttctatcctt ggacttgctg gtactggtaa tggtatcacc
     7081 atcatccctg gtacaatgct ttatgttggt aacggacaac ttccacaata ccttcttatg
     7141 gtagctgtat catttgccct tggttttgct cttacttaca tgtttggtta cgaagatgaa
     7201 gtagacgcaa ctgcagctgc aaaacaagct gaagtggctg aagaaaaaga agaagttgcg
     7261 ccagcagctc ttcaaaatga aacacttgta actcctatcg tcggtgatgt tgtcgctctt
     7321 gctgatgtca atgacccagt cttctcaagt ggagctatgg gacaaggtat cgctgtgaaa
     7381 ccaagtcaag gcgtggtcta tgcactagct gatgctgaag tttcaattgc ctttccaaca
     7441 gggcacgctt ttggtttgaa aacaagaaat ggtgctgaag ttttgattca cgttggtatt
     7501 gacactgtat ctatgaacgg tgacggtttt gaagcaaaag ttgctcaagg taataaggtg
     7561 aaagctggcg atgttcttgg aacatttgac tcaaacaaaa tcgctgcagc tggacttgat
     7621 gatacaacaa tggttatcgt tacaaataca gctgactacg cttcagtagc tccagtcgca
     7681 acaggttcag tttcgaaggg ggatgctgtg atcgaagtga aaatctaatc aatcctctct
     7741 aatgtgaaaa cgaacaaatg acatgtttgt tcgtttttat tagatagtaa gatttacaga
     7801 ggaaaatcta aaaaatagag acatttagac tttcgaagta tgctataata aagaaaataa
     7861 aaacaagagg tttatcatga caaaattata tggaagcttg gaagcgggcg gtacaaagtt
     7921 tgtctgtgct gtcggtgatg aaaactttaa cgttgtagaa aaaacacaat ttccaacaac
     7981 aactccaatc gaaacaatcg ataaaaccat tgagttcttc tcaaaattcg ataaccttgc
     8041 tggtcttgca gttggttcat ttgggccgat tgatattgac aaaaactcaa aaacttatgg
     8101 ctttatcacg acgactccaa aaccaaactg ggcaaatgtg gacttgcttg gtgcccttcg
     8161 tcgcgcccta aacgtgccaa tgtacttcac aacagacgta aacagctctg cttacggtga
     8221 aatggttgct cgtaacaatg ctggtggtcg tatcgaaaac ttggtttact acacaatcgg
     8281 tacaggtatc ggtgcaggcg tcatccaacg tggtgagttt atcggtggtg tgggtcaccc
     8341 tgaaatgggt cattattatg ttgctagaca cccaatggat attgaaaaag agtttaaggg
     8401 tgtttgtcct ttccataagg gatgtctaga aggttatgca gctggtacaa gtttggaagc
     8461 tcgtacaggt gtacgtgggg aaactattga actcaacaac cctgtttggg atgttcaagc
     8521 ctactatatc gctcaagctg cggttaatgc gacagtgact ttccgcccag acgtgattgt
     8581 ctttggtgga ggggtcatgg ctcaacaaca tatgctggac cgtgtccgtg agaaatttac
     8641 atctcttctt aatggttacc taccagtacc agatgtgcgt gactatatcg tgacgccagc
     8701 agtcgcagga aatggttctg ccacacttgg gaactttgtt cttgcaaaag aagtttcaaa
     8761 ataaagcaca aaatccgctt gggaaaccaa acggattttg tggttgaaaa caatattttt
     8821 gagcctttcc ttaagtgatt acggacggta gcgactttct tcgaaattcc atacctaaac
     8881 tttgagccta gtgtctcaaa gtttccgaat acctgaaacc attagatttc aggtgtttct
     8941 atcacggcgg aaaggctagg taagtcctcg cctcactatc gaaaaatatg cataatttcc
     9001 ataccaaagt atatttagta tcaagctata gttaatctac gctttaaaaa tccacttggg
     9061 aaaccaaacg gattttttac gtgtcaaagc atttgccaga aaaagtcaat aatataggtc
     9121 agaccgtagg tataaaccac gagggtaaag ggtttggtca gaatgatgat agtcatgtag
     9181 cgcttgaaac tcatcttggt cagggcggcc agcatacaga gaaagtcagc tgggctaatg
     9241 ggccaaatca tcataaaaat aaagaagcgg tcaaaacgat tgcccttatc tagccagccg
     9301 atgtacttgt cgtaggtgcg cttgctgacg acagactgga caaaggcagc tccgtatagg
     9361 cgcactagat aaaagataat ggcacagcca atcacgatgc cgatatagtt gtagatagtc
     9421 ccgatgatgt gcccgtagat aaagacccca gccaccgagg tcaaggcccc tggaatgata
     9481 gggacgacag tctgtaaaat ctgtaaaaag ataaagagag gtggacccca gatgcctgcc
     9541 tgctggataa aggcagagag ggtttccttg gattgtaaaa tcccagcctg ataagcccaa
     9601 atacagaaaa tcaaactccc aaccccaccg acaatcgatg agatattgat aactcgctgc
     9661 agaaggggag aaacagcttt catttgttta tcctgtgaca tgtaaactcc tcatagatag
     9721 tatatttcta ctataccata ttttggagga gaaaggggga atgagtcttt tttgataagg
     9781 aatagaaagt aaatagccct tcgagactta gaataggtct gtcaactaaa ggttatatgc
     9841 attctaggtt tcgaataatc gcaattccat aaatttaaaa gtattctaag tttcgaatag
     9901 cttatctgag ataattttga ggcattcgcg ctttcgaata gtcattttcc ctaaagttta
     9961 tatgtattct gaagctagaa agactaaaat ataaaagtag taagagtctc tctctgatgg
    10021 acgtaattta tggctagtat gaatcctttg aattgttagt taattttaat attaatcagt
    10081 tctgaaataa ttactaaata tagttagatg gtgagttaat tattgctaaa tttcaagttc
    10141 aagttagtca tccagaagtc ttctctgggg gacttgtagt tcaagcattt tttaggatag
    10201 ttgttaatcc acttttcgat aaatgcgact tcctttgtag ttgttttctt agttccctga
    10261 ggtaaccatc tatgaatgag cctgttgtga ttttcattag atcctatagt gatgtgcata
    10321 atagatatag cagattgaaa ctagaatagt atacatctac ttctaaaaca ttgttagaaa
    10381 tcaatttgac tgtcctgatc aatttgtcct gtttttattt cattttacta tataatcctt
    10441 agaaaacata tcggacaagc ggttgaattc cgttccgtcc attagtagat aaaggattac
    10501 tccttcttga aatgacagat gaacttgttt cttataaaaa tgttgtctga aactattagc
    10561 ctttttccag aagttttaga ggaagaaaac tttacgagga aaaaggagtt actcaaataa
    10621 caattcagga ttaaaaatag acagttgagg agcggaaggt ataaattaag tttgctactg
    10681 tataatggat ttatcactaa tactcttcga aaatctcttc aaaccacgtc agcttcgcct
    10741 tgccgtagat atagttactg acttcgtcag ttctatccac aacctcaaaa cagtgttttg
    10801 agctgacttc gtcagtttta tctgcaacct caaagctgta ctttgagcag cctacggcta
    10861 gcttcctagt ttgctctttg cttttcattg agtataaaag tgctccaggc catattttac
    10921 acagcaatag tcttctaaaa atggacaaaa acattgtaaa ggctatcaaa aaggagtata
    10981 atgagtgcaa gaaatttcgg aggtgaaaga tgctagaagt aagaagtcta gagaaaagtt
    11041 ttggctccaa gcaagttttg tttggtattg actttcaagc gcgaccaggt cgtattttgg
    11101 gactagtcgg aaaaaatggt gctggaaaaa caacgatttt ccatagtatt ttgaaattcc
    11161 tagaatatca gggagaaatc ggtctggatg gtcaggatat tcgtcaggag acctatgctc
    11221 ggattggtta tctgcctgaa gaacgcagtc tcatgcctaa attgacagtt cttgaacaag
    11281 ttcgctactt ggcgactcta aaaggcatgg atgccaaaga agtcaaagaa aaactccctc
    11341 aatggatgaa gaggttggaa gtgaaaggaa agctgacaga taaaatcaag agtctgtcaa
    11401 aaggaaatca gcagaagatt cagctcatta ttactctgat tcatgaacca gacctgatta
    11461 tcttggatga gccttttagt ggattggacc cagttaatac agaattgctc aaacaagtca
    11521 tttttcagga aaaagagcgc ggagcaacca ttatcttttc tgaccatgtc atgaccaatg
    11581 ttgaggaact ttgtgacgat attctgatga tccgagatgg ccgtgtggtc ttgcacggac
    11641 cagttcagga tgtccgcaat caatacggga aaacgcgtct ctttgtttca agtgaacgaa
    11701 gcaaggaaga attggaaaat cttcctcatg tcaaacaggt gagcttgacc aaacaaggca
    11761 gttggaaatt gattttggag gatgagagcg ctggaaggga actcttccca atcttgactc
    11821 aaggtcaata tatcgcaaca tttgaccaac aagcgccaac tatcgatgaa atctttaaac
    11881 tagaatcagg agtggaagta tgagaaatat gtgggttgta atcaaggaaa cctatcttcg
    11941 acatgtcgag tcatggagtt tcttctttat ggtgatttcg ccgttcctct ttttaggaat
    12001 ctctgtagga attgggcatc tccaaggttc ttctatggct aaaaataata aagtggcagt
    12061 agtgacaaca gtgccatctg tagcagaagg actgaagaat gtaaatggtg ttaacttcga
    12121 ctataaagac gaagcaagtg ccaaagaagc aattaaagaa gaaaaattaa aaggttattt
    12181 gaccattgat caagaagata gtgttctaaa ggcagtttat catggcgaaa catcgcttga
    12241 aaatggaatt aaatttgagg ttacaggtac actcaatgaa ctgcaaaatc agcttaatcg
    12301 ttcaactgct tccttgtctc aagagcagga aaaacgctta gagcagacaa ttcaattcac
    12361 agaaaagatt gatgaagcca aggaaaataa aaagtttatt caaacaattg cagcaggtgc
    12421 cttaggattc tttctttata tgattctgat tacctatgcg ggtgtaacag ctcaggaagt
    12481 tgccagtgaa aaaggcacca aaattatgga agtcgttttt tctagcataa gggcaagtca
    12541 ctatttctat gcgcggatga tggctctgtt tctagtgatt ttaacgcata ttgggatcta
    12601 tgttgtaggt ggtctggctg ccgttttgct ctttaaagat ttgccattct tggctcagtc
    12661 tggtattttg gatcacttgg gagatgctat ctcactgaat accttgctct ttattttgat
    12721 cagtcttttc atgtacgtag tcttggcagc attcctagga tctatggttt ctcgtcctga
    12781 ggactcaggg aaagccttgt cgcctttgat gattttgatt atgggtggtt tttttggagt
    12841 gacagctcta ggtgcagctg gtgacaatct cctcttgaag attggttctt atattccctt
    12901 tatttcgacc ttctttatgc cgtttcgaac gattaatggc tatgcggggg gagcagaagc
    12961 atggatttca cttgctatta cagtgatttt tgcggtggta gcaacaggat ttatcggacg
    13021 catgtatgct agtctcgttc ttcaaacgga tgatttaggg atttggaaaa cctttaaacg
    13081 tgccttatct tataaataga agagccttgc gaaagcgagg tttttaaagg tgaaaagggt
    13141 ggaatcacga acctaatgat gtacacatta tgtaaacagg ttgcttgaaa actcaattgt
    13201 atagtgaact gaatctggaa taggataata ttacttctaa aacattctta taaattgatt
    13261 tgaattccaa aatcccatcg ttccgttctt atttcatttt gcgatatagt gaaaggaaat
    13321 aagtcagctc acaaaaaacg cataatatca aggattttta acacttgata ctatgcgttt
    13381 tctaatttta aagacttttt gcctggtctc ttttgttcta tgagtatgtt acatatctag
    13441 gtaaaaatta tttaaagcaa attaacctta tttctcaaga tgtagtaggt tccgagataa
    13501 aagatagcta tgaatatgag ttctttaaca atggctatac ctgctcccat atagaaatgg
    13561 tcattgagtc ctaccagtga attgacatag aaattagaac taagattgaa gaaaagttca
    13621 ataaatccaa tgacgatttg gataccaatg taggctgcaa cagcgagtgc tgtacggtat
    13681 tcattgaaaa gctgtccaat ggaaatagcc aggtagatgc agaggattcc tgaaatggta
    13741 tttagtagga aggatatacc tgtaagaaag atctgaggga gatgtgtttc tacaaatgta
    13801 atcacataag aaagaggaat ccattctgga gctgttaaag ccagaataat aacagcactt
    13861 agagccaata cagcggtgct aatcaatgac cagataaagg caccgattag tttggctgtg
    13921 atgatatggt gttcagaaac tggcaaggtc aaagtcagat agccttgtcg gtcgtagaca
    13981 ctacctttga agcgtttaat aatcaagaaa atggttgaaa tcgcaagtgt aagcatcaag
    14041 ccaccaaaga ctgtagctag aaaaagtagc atagtagcct gactttcttg gtaaggtaga
    14101 tttttaaagc cttgtgtctg tattccgatg agggcagaaa ggactagcac ggctgcgtag
    14161 agggctaaat accacttgtt aacattttta aattcgtagt gaactaaatt ccaaaacata
    14221 aataatctcc tttgcttagg ccttaaattc ctgacggaag agttggtcaa tggattcacc
    14281 tgactcgtag cgaatatcat ctacatttcc ttgacggacg acttttccgt cttttaggaa
    14341 gacaatttca tccaagattg gctcgatatc agaaatcaag tgggtagaaa tcaaaacggt
    14401 agaagttggt gagtagttgt tgataatggt attgaggata taagcacggg ctgctggatc
    14461 caccccacca atgggttcat ccaaaacata gagacgagca tcacggctca taaccaaaat
    14521 cagttgaacc ttttctttgt ttccttttga tagtttcttg agacgactat tttcatcaat
    14581 gcccaggtct gcaagtagat gatgagcgcg ttcaagattg aaatctttat agaaggtctt
    14641 gaagtaggtt agggcttctt tgaccttcat ttgctcattg agataggtcg tatcaggcaa
    14701 ataagctaca acggccttgg ttgctgggct tgggtccatg tcgttgatga ggacacgtcc
    14761 ttgatctggt tgtaagaggc cattaattag tttaatcagg gttgtttttc ctgagccgtt
    14821 tggcccaaga aggccgacaa tttttccagc tggaatgtca agagaaacat tttcaagggc
    14881 tggtgttgct ccatatgatt tggatacatt ttcaaatact agtaatgaca taggcttaaa
    14941 ctcctttaat ataatcactg actacgcctg gtagttcttc tttttcatag ccaaaatgga
    15001 tcatggagga aacgaagtgt tccaattctt cttctgataa ttgtttgcgt gactgagcga
    15061 ttagctcctt atccttagtc acaaatcgtc cagttgttcg cttgctgtag acaaatcctt
    15121 ctcgttcaag gtctgataag gctctttgga tggtattggg attgacacca gcctcgctag
    15181 ctagctccct cacggttgga agttgttgat tgggttccag tgtatgggaa acaatctgaa
    15241 gcttgatttt ctccataatc tgtaaataga tgggtttttt gttgtcaaat gtccaggaca
    15301 tcttagtctc ctttctctta tccttttgtc ttaactaaat aatacaacaa aacaaaaaac
    15361 ttgtcaagca aaaagaagaa ttgttttggg aatcgcttaa aaaatggtat aatgaaaaga
    15421 aaacgataag gagggaaagg atgcgttgtc caaaatgtgg ggctaccaag tcaagtgtta
    15481 tcgatagtcg ccaagcagaa gaagggaaca ccattcgtag aagacgtgag tgcgacgaat
    15541 gccaacaccg ttttacaacc tacgaacgag tagaagaaag aaccttagtg gttgttaaaa
    15601 aagatggtac acgggaacaa ttctccagag ataaaatctt taatgggatt atccgctcag
    15661 cccagaaacg tcctgtgtca agtgatgaaa tcaacatggt agtcaatcgt atcgaacaga
    15721 aactccgtgg tcgaaatgaa aatgaaattc aaagtgagga cattggttca ctcgtcatgg
    15781 aggagttggc tgaattggac gagattacct atgtacgttt tgctagtgtc tatcgtagtt
    15841 ttaaggatgt cagtgagtta gagagcttgc tccaacaaat cacccagtcc tctaaaaaga
    15901 aaaaggaaag ataaatgaag ccaattgacc gtttttctta tctaaagaat aatcgggtgt
    15961 cgcaagatac ctcatctctg gtacagtgct acctcccgat tatcggtcag gaggcactga
    16021 gcctttatct ttatacaatc agtttttggg ataatggtag aaaggaatat cttttttcaa
    16081 gtatcctcaa tcatctcaac tttgggatgg atagactgat aaaatcattg aaaatcttat
    16141 ctgcttttaa tctcttgacc ctctatcaaa agggggatgt ttatcagcta gccctccatg
    16201 ctcctctatc tagtcaagac ttcttggagc atcctgttta tcgcagactc ttagagaaaa
    16261 agattggcga ctctgctgtg gaggatttga aagttgaaag tgctgatggt gaagaaatac
    16321 ctgtctcact caatcaagtc tttccagaat tggcagaact aggcagtcaa gaagaccttg
    16381 gtctcaagaa gaaagtggcc aatgattttg acttggaaca ttttcgccag ctgatggctc
    16441 gagatggact tcgttttgcg gatgagcagt ccgatgtctt aaacctcttt gctattgccg
    16501 aggagaagaa atggacttgg tttgaaacct atcaattggc caagtcaaca gctgtttctc
    16561 aggttatttc aaccaaacgc atgcgtgaaa aaattgctca aaaaccagtt tcctctgact
    16621 ttaatcctaa ggaagcaacc attatcaagg aagctaaaag taagactgcc ctgcagttct
    16681 tagcagaaat caagcaaaca cgcaagggga ccattaccca aacagaaaga gaacttttgc
    16741 aacagatggc tggcttgggc ttgctggacg aagtcatcaa tatcattctc ttgttgacct
    16801 ttaataaggt ggattcggca aacatcaatg agaaatatgc catgaaggtg gctaatgact
    16861 atgcctatca aaagatacat tcagcagaag aggccgtttt acgaattcgt gagcgagggc
    16921 agaaaacaaa aacacaaaaa cagaatcaga ctgccccagc aaaaaccaat attcctaaat
    16981 ggagtaaccc agattataag aatgaaacca gcgaggaaac tcgtctggaa ctagaacgta
    17041 agaaacaaga actattagct cgattagaaa aaggaggaga ttagatggaa agtgtcggag
    17101 acgtactcaa acgtcaaccc agccgttttt attatcaaga tttggtccag aaaatcatga
    17161 aggaccctga tgttgcggct tttatccagc aagaatcctt gactccagag gaattaaatc
    17221 gcagtatctc caagtttaat cagtacatca ccgagcgtga caagtttctc cgtggggata
    17281 cggattatat tgccaaaggc tacaagccga ttttggttaa gaatcatggc tatgcagatg
    17341 tttcatatga agaaactcct gagctaatcg cggctgaaaa agaagcggct attaagaatc
    17401 gtctcaagct aatcaatcta ccagccagtc tcaaaaaagc tagtttggct caagttgatt
    17461 tggatgattt gggacgcttg ccagtttttg aaaaactatt agcctttgtg gagcaatatc
    17521 cagctattcg aaaaggtctt tacttatatg gagactttgg tgtgggtaaa agtttcatgg
    17581 tggcggcctt agctcatgat ttatcagaaa aacgtggtgt ttcatcaact ctcctccact
    17641 atcctagctt tgtcattgat gtcaaaaatg ctatcagtga tggcaatgtt aagaccttgg
    17701 tggatgagat taagctgtct gaggtcctga ttttagatga tattggcgcc gagcaatcaa
    17761 ccgcttgggt gcgtgacgaa atcctgcagg tcattctcca atatcggatg caggaaaatt
    17821 taccgacctt tttcacatcc aacttcaact ttgaagattt ggagaagcat tttgcgaaag
    17881 tgaaacatgg aaatgacgaa acctgggaag ccagacgggt catggaacgc atccgttatt
    17941 tggctgagga gactcgttta gaaggagtaa accgtcgatg acagaaacca ttaaattgat
    18001 gaaggctcat acttcagtgc gcaggtttaa agagcaagaa attccccaag tagacttaaa
    18061 tgagattttg acagcagccc agatggcatc atcttggaag aatttccaat cctactctgt
    18121 gattgtggta cgaagtcaag agaagaaaga tgccttgtat gaattggtac ctcaagaagc
    18181 cattcgccag tctgctgttt tccttctctt tgtcggagat ttgaaccgag cagaaaaggg
    18241 agcccgactt cataccgaca ccttccaacc ccaaggtgtg gaaggtctct tgattagttc
    18301 ggtcgatgca gctcttgctg gacaaaacgc cttgttggca gctgaaagct tgggctatgg
    18361 tggtgtgatt atcggtttgg ttcgatacaa gtctgaagaa gtggcagagc tctttaacct
    18421 acctgactac acctattctg tctttgggat ggcactgggt gtgccaaatc aacatcatga
    18481 tatgaaaccg agactgccac tagagaatgt tgtctttgag gaagaatacc aagaacagtc
    18541 aactgaggca atccaagctt atgaccgtgt tcaggctgac tatgctgggg cgcgtgcgac
    18601 cacaagctgg agtcagcgcc tagcagaaca gtttggtcaa gctgaaccaa gctcaactag
    18661 aaaaaatctt gaacagaaga aattattgta gaaagtgaga aattatggcc ctaccaacta
    18721 ttgccattgt aggacgtccc aatgttggga aatcaaccct atttaatcgg atcgctggtg
    18781 agcgaatctc cattgtagaa gatgtcgaag gagtgacacg tgaccgtatt tatgcaacgg
    18841 gtgagtggct caatcgttct tttagcatga ttgatacagg aggaattgat gatgtcgatg
    18901 ctcctttcat ggaacaaatc aagcaccagg cagaaattgc catggaagaa gcagatgtta
    18961 tcgtctttgt cgtgtccggt aaggaaggaa ttaccgatgc agacgaatac gtagcccgta
    19021 agctttataa gacccacaaa ccagttatcc tcgcagtcaa caaggtggac aaccctgaga
    19081 tgagaaatga tatctatgat ttctatgctc tcggtttggg tgaaccattg cctatctcat
    19141 ctgtccatgg aatcggtaca ggggatgtgc tagatgcgat cgtagaaaat cttccaaatg
    19201 aatatgagga agaaaatcca gatgtcatta agtttagctt gattggtcgt cctaacgttg
    19261 gaaaatcaag cttgatcaat gctatcttgg gagaagaccg tgttattgct agtcctgttg
    19321 ctggaacaac tcgtgatgcc attgataccc actttacaga tacagatggt caagagttta
    19381 ccatgattga tacggctggt atgcgtaagt ctggtaaggt ttatgaaaat actgagaaat
    19441 actctgttat gcgtgccatg cgtgctattg accgttcaga tgtggtcttg atggtcatca
    19501 atgcggaaga aggcattcgt gagtacgaca agcgtatcgc aggatttgcc catgaagctg
    19561 gtaaagggat gattatcgtg gtcaacaagt gggatacgct tgaaaaagat aaccacacta
    19621 tgaaaaactg ggaagaagat atccgtgagc agttccaata cctgccttac gcaccgatta
    19681 tctttgtatc agctttaacc aagcaacgtc tccacaaact tcctgagatg attaagcaaa
    19741 tcagcgaaag tcaaaataca cgtattccat cagctgtctt gaacgatgtc atcatggatg
    19801 ccattgccat caacccaaca ccgacagaca aaggaaaacg tctcaagatt ttctatgcga
    19861 cccaagtggc aaccaaacca ccaacctttg tcatctttgt caatgaagaa gaactcatgc
    19921 acttttctta cctgcgtttc ttggaaaatc aaatccgcaa ggcctttgtt tttgagggaa
    19981 caccgattca tctcatcgca agaaaacgca aataaaaaag tagaatctgg aatgacagtt
    20041 ccggattttt ttgatataat aaaataatag aaaacgctat caaaagaagg agggtgatgt
    20101 cggtgatgga acatttgttt aaattcttac ttttagcacc gtacttttat tttgataact
    20161 ggattgagaa ggccaacaga aatagtaagt tttttccaat tttttattat ttttactggt
    20221 tttacatccc cttctattct ctttttagcc ttgcttggac agttgtttca gttctgtttt
    20281 tcaataccgt cttgagaaat gtgacagata tcaagttatg gggcatttgg tttcttttta
    20341 ttctgctagc tattggtatg aattggttaa cttattcctg tttcaaagaa atgtttcgct
    20401 tgagacagga actagggaag tctaagggtg gaaggcattg atttatatcg gtttctattt
    20461 gtaggaggtg gcttatggta cctctaaaat catttattac acgctattcc aaggtttata
    20521 ttggtaataa catttaatag aacgaaacta aagaaaacaa tttaaaagag gaggtttgtg
    20581 atggaatact tgtttaaaat gataatctta ttaccctgtt tttacttttt cagctggatt
    20641 gaaaaggcaa acagagatag taagattttc ccaatttttt actattttta ctggatttac
    20701 atcaccctct atgctctttt tagccttgct tggacagttt tttcagttct gtttttcaat
    20761 atcgtcttga gaaatttgac agatatcaag ttatggggta tttggctatt attactactt
    20821 atcgcttttg ctagtgactg gttagactat atctgtttca aaaaaatgct tgacttgaga
    20881 cgggaactag ggaagtctaa aggcggaagg cattgattta tactcttcga aaatctcttc
    20941 aaaccacgtc aacgtcgcct tggattatat atgtaactga cttcgtcagt cttatctaca
    21001 acctcaaagc agtgctttga gcaacttgcg gctagtttcc tagtttgctc tttgattttc
    21061 attgagtatt atattacttt ctatttgtag gaggtggctt atgaagattc ctctcttaac
    21121 tttggcaagg cataaatttg tttatgtctt gcttactttg ctttttcttg ctttggttta
    21181 tcgtgatgtt ttgatgactt atttcttttt tgatattcat gcgcccgatc tagctaaatt
    21241 cgatggacaa gcaattaaaa atgacttatt aaaatcagca ttagattttc gtattctcca
    21301 gttcaatcta ggtttttatc aatcatttat tattccaatc atcattgttt tgctaggttt
    21361 tcaatatatt gagctgaaaa ataaagtttt acgattgagt attggaagag aagtgagcta
    21421 tcaagggtta aaaagaaagt tgactttgca agttgcaagt atcccttgtt tgatatattt
    21481 agtgactgtg ctgataattg caattataac ctatttcttt gggacttttt ctcctcttga
    21541 atggaattct ctattttctg atgggagtgg tttacaaaga ctcctagatg gagagataaa
    21601 aagctatttg ttctttactt gtgtcctact aatcggtatt ttcatcaatg caatctattt
    21661 tttacaaata gttgattatg tggggaatgt gactcgttcg gcaatcacct atttgatgtt
    21721 tctttggctt ggttctatgc tgctctatag tgccttgcct tactatatgg ttcctatgac
    21781 gagtttgatg caagctagct atggggatgt aagtttgatg aaactcttta ctccttatat
    21841 cctttatgtt gtcccttata tggtacttaa aaaatatgaa gataatgttt aagaatttta
    21901 acaatatttg gctaaagaga aagatcgttt tactacttcg tatagttctg atgatgattt
    21961 tgataaacta tctattgtca acagcggttc aaaagcagga tgctgttatc tttttcaaga
    22021 gagaattgat ttcaattttt tcctataatg actattctga agcgaattta gaaatcccca
    22081 aactcttgtt aaacctttcg cttttcatgg taggatggct ctctgtcatt ttacttgaaa
    22141 gtgatttggc agaccattac catcacttga ttcgctatca atcaagctcc tttttcgatt
    22201 atacaaggaa acgattggtt gtcatttcta aattttttac tcaagatttg tttgtctggt
    22261 ttcttggttt acttccgcta ggaattcatt tcaaaacagt cgcacttttc tttttacttg
    22321 ctcagttaat gatgttgtac ttactactgt cttatctgat agcactgatt agtgcgggcg
    22381 ctggtttttc tttttttctc tattttttgg catttgtggg acaagaatgg atgatggatc
    22441 atattgtaac agtgtattta gtactcttaa gcttattagt tatgttgatt gttagtcgct
    22501 tggaagagaa atttaagaaa ggataaacga tgagacttga aattataaat ggacagaaaa
    22561 tttatgggaa aagacctatt ttaaatcagt tgaatttggt gtttcaatca ggaaaaattt
    22621 atggacttaa aggtgataat ggatctggca agacggttct tttaaagata cttgctggtt
    22681 atattaagct tgacaaagga aaagttcttc aagatggtaa agtttacggg gtaaaaaatc
    22741 attatattca ggatgcagga attttaattg aaaaagtcga gtttttatct catttatccc
    22801 tgagagaaaa tttggaactg ttaaggtatt tttcatctaa agttacggaa aaaagaattg
    22861 cctattggat tcaatactat gatttacagg aatttgaaga cgttgaatac cgtcatttat
    22921 ccttgggaac aaagcaaaaa atggccttga ttcaagcctt tatttcctct ccttctatac
    22981 tctttctcga tgaacctatg aatgctttgg atgagaagag tgtgaggtta accaaacagg
    23041 tcattttatc ttacctgaaa aaagaaaatg gtctggttat cctgacgtcg cacatatcgg
    23101 aagatatttc agacctttgt acagatgtat tagttgtcga aaatggacat atacaatatg
    23161 taaaggatat acaatcctag gagatggctt atggcacatc taaaatcatt tattacacgc
    23221 tattccaagg tttatattgg tttagttctg ctgatctggc tgtctttctt ctttatccct
    23281 tgggatagag cgattctggg ggtaaggatt gacatcttca tcatgcagaa aatcttgcta
    23341 gcttttggaa ttctgtccat tctcatggcc ttgctgtcca agaaagtcag tctctttgtt
    23401 tttggactga tttgctgtct ttctctttgg attaacttat ttatcacatt tgccattttg
    23461 ccgatttttg gcaattaaac agtcataaaa gtcggagagg ttagcttgaa aactaacctc
    23521 tttttccttt tcaaaatggg gattcttcct tgaaaataat cagtaattgt gctaaaatta
    23581 aaggaacatt ctaaaatatt cggaatttaa agtaaggaaa aacatggcta atattttaaa
    23641 aacaattatc gaaaatgata aaggagaaat ccgtcgtctg gaaaagatgg ctgacaaggt
    23701 tttcaaatac gaagaccaaa tggctacttt gactgacgac caactaaaag caaaaacagt
    23761 tgaatttaag gaacgttatc aaaatggaga atcactggat tcattgcttt acgaagcatt
    23821 tgcggttgtc cgtgaaggtg ccaaacgtgt cctaggtctc ttcccttata aggttcaggt
    23881 catggggggg attgttcttc accatggtga cgtgccagag atgcgtacag gggaagggaa
    23941 aaccttgact gcgaccatgc cggtatacct caatgccctt tcaggtaaag gggttcacgt
    24001 agttacggtt aatgaatacc tgtcagaacg tgacgcgact gagatgggtg aattgtactc
    24061 ttggcttggt ttgtcagtag ggattaactt ggctaccaaa tctccaatgg agaaaaaaga
    24121 agcctatgag tgtgatatta cttactcaac taactcagaa atcggatttg actaccttcg
    24181 tgacaacatg gtcgttcgcg ccgaaaacat ggtacaacgt ccgcttaact atgccttggt
    24241 cgatgaggtt gactctatct tgattgacga ggctcgtaca cctttgattg tatcaggtgc
    24301 caatgcggtt gaaaccagtc agttgtatca catggcagac cactatgtaa aatctttgaa
    24361 caaagatgac tacatcatcg atgtgcagtc taagactatt ggtttgtctg attcagggat
    24421 tgacagggct gaaagctact tcaaacttga aaacctctat gacatcgaaa acgtggcttt
    24481 gactcacttt atcgataacg cccttcgtgc caactacatc atgcttctcg atattgacta
    24541 tgtggtgagc gaagagcaag aaatcttgat tgtcgaccaa tttacaggtc gtaccatgga
    24601 aggtcgtcgt tattctgatg gattgcacca agctattgaa gccaaagaag gtgtgccaat
    24661 ccaggatgaa accaagacat ctgcctcaat cacgtaccaa aaccttttcc gtatgtacaa
    24721 gaaattgtct ggtatgacgg gtacaggtaa gactgaggaa gaagaattcc gtgaaatcta
    24781 caacattcgt gttattccaa tcccaacaaa ccgtcctgtt caacgtattg accactcaga
    24841 ccttctttat gcaagtatcg aatctaagtt taaagcggtt gtcgaagacg ttaaggctcg
    24901 ttaccaaaag ggtcaacctg tcttggttgg tacagtagcg gttgaaacta gtgactacat
    24961 ttctaagaaa ttggttgcag ctggtgttcc tcacgaagtc ttgaatgcca aaaaccacta
    25021 tagagaagcc caaatcatca tgaatgctgg tcaacgtggt gccgttacca tcgcaaccaa
    25081 catggcgggt cgtggtaccg acatcaagct tggtgaaggt gttcgtgaac ttggaggact
    25141 ttgtgttatt ggtacagaac gtcatgaaag tcgtcgtatc gataaccagc ttcgtggacg
    25201 ttcaggtcgt caaggagatc caggtgagtc acaattctac ctatctcttg aagatgattt
    25261 gatgaaacgt tttggttctg aacgcttgaa gggaatcttt gaacgtttga acatgtctga
    25321 agaggcgatt gagtctcgca tgttgacgcg tcaggttgaa gcagctcaga aacgtgtcga
    25381 aggaaataac tacgataccc gtaaacaagt ccttcaatac gatgatgtca tgcgtgaaca
    25441 acgtgagatt atctatgctc aacgttacga tgtcatcact gcagatcgtg acttggcacc
    25501 tgaaattcag gctatgatca aacgcacgat tgaacgtgtc gttgatggtc atgcgcgtgc
    25561 caaacaagat gaaaaactag aggcaatttt gaactttgct aagtacaact tgcttcctga
    25621 agattctatt acgatggaag acttgtcagg cttgtctgat aaggccatca aggaagagct
    25681 tttccaacgt gccttgaagg tttacgatag tcaggtttca aaactacgcg atgaagaagc
    25741 agttaaagaa ttccaaaaag ttttgattct acgagtggtg gataacaagt ggacagatca
    25801 tatcgatgcc cttgatcaat tgcgtaacgc ggttggactt cgtggctatg ctcagaacaa
    25861 ccctgttgtt gagtatcagg cagaaggttt ccgtatgttt aatgatatga ttggttcgat
    25921 tgagtttgat gtgacacgct tgatgatgaa agcacaaatt catgaacaag aaagaccaca
    25981 ggcagaacgt catatcagta caacagcgac tcgcaatatc gctgctcacc aagcaagtat
    26041 gccagaagat ttggatttga gccagattgg acgcaatgaa ctttgcccat gtggttctgg
    26101 taagaaattt aaaaactgtc acggtaaaag acaataaaat gagatagttt agaggcggat
    26161 atcttgtgaa aagtaaattt ttactgggta tccgtttgct ttataaggag atgagttatg
    26221 gtatttacag caaaaagctc taaaataaat atagaagaag ttcgtgcctt gtcaaaatta
    26281 gaaggtcagg ctttggagag gaaatcacag cgcgatcaag agctagaagc cattatacgt
    26341 ggagaagatc agcgaattct cttggtaatc gggccatgct catctgacaa cgaagaagct
    26401 gtccttgaat acgctaagcg tttggcagtc ctacaagaag aagtggcaga tcgtatcttt
    26461 atggttatgc gtgtttatac tgccaaaccc cgtaccaacg gagatggcta taagggcttg
    26521 attcaccagc ctaacgcgac agaagcgcct agtcttatca atggaatcaa agccgttcgc
    26581 catcttcact atcgtgtcat cacagaaaca gggatgacaa ctgctgatga aatgctttat
    26641 cctgaaaacc ttccgcttgt agatgatttg atttcttaca tggcagttgg tgcccgttca
    26701 gttgaagacc agcaacaccg ctttgtggca agtggggcag gattttctac tggttttaaa
    26761 aatccaacct ctggaaatct caatgtcatg tttaatggga tttatgctgc tcaaaacaaa
    26821 caaagtttcc ttttcttagg aaaagaagta gaaacaactg ggaacccgct ttcacacgct
    26881 attcttcgtg gtgctcttaa tgagtatgga aaaaatattc ccaactacta ttatgacaat
    26941 ttaattgata ccattgccca atatgagaaa atgggcttgg aaaatccttt tatcatcatt
    27001 gataccaatc atgacaattc tggtaagcag tatattgaac agatccgaat tgtccgccag
    27061 accttgatta accgtgcttg gaatgaaaaa attaagcagt tcgttcgtgg ttttatgatt
    27121 gagtcttatc tggaagatgg tcgacaaaat gagccagaag tatttggcaa gtctatcaca
    27181 gacccttgcc tgggttggga taacacagaa gctcttgtca gagaaattta caaaacgtta
    27241 ggagaataag atggcattta ttgaaaaagg tcaagaaatc gatatggaag tcatcaaggc
    27301 tgaaacccaa ttgtctgcgg aagccttgag actcaaggaa agccgtgaca gggaattggc
    27361 agatattatt tcaggggaag atgaccgtat tctcttggtg attggtcctt gctcttctga
    27421 taatgaagag gcggtcttgg aatatgctcg ccgtttatcc gccttgcaaa agaaggtagc
    27481 ggacaagatt ttcatggtca tgcgcgtgta tactgctaag cctcgtacca atggagacgg
    27541 ctataaagga ttggttcacc agccagatac ttctaaggct ccaagcctga ttaacggttt
    27601 gcaggctgtg cgccagttgc attaccgcgt gattacagag actggtttga caacggcaga
    27661 tgagatgctt tatccgtcaa atctgatctt ggtggatgac ttggtcagct accatgccgt
    27721 tggagctcgt tctgtggaag accaagagca ccgctttgtg gcttctggga ttgatgcacc
    27781 agtagggatg aaaaatccaa cctcaggaaa tttgggtgtt atgtttaacg ccatctatgc
    27841 tgctcaaaac aagcaaacct tcctttatca tgggcaggaa gttgagacat caggtaatcc
    27901 tttggcccat gttatcctcc gtggagcagt caacgagtat ggcaattata tgccgaatta
    27961 ctactatgaa aacctactcc aagccattga acgctatgaa accatgggac ttgaaaatcc
    28021 ttttatcctc attgacacca accatgataa ctcaggcaag caatatatgg agcagattcg
    28081 aattgttcgc cagaccttgc agaatcgtga ttggaatgag aaaattaaaa agacggttcg
    28141 aggatttatg attgaatctt acctagcaga tggtcgtcaa aaccaaccag agatctttgg
    28201 ttgctctatt actgaccctt gcctaggttg ggaaaataca gaggccttgg tagaagagat
    28261 ttatgttacc ttgacaaaat aagtgaaaag gatggagttg gggaatctca actccttttg
    28321 atgagaatga tagttggaca cggaattgac atcgaagaat tggcttcgat agaaagcgca
    28381 gttacacgac atgaaggatt tgctaagcgt gtactgaccg ctcaggaaat ggagcgcttc
    28441 accagtctca aaggacgcag gcaaatagaa tatttagctg gtcgctggtc ggctaaggag
    28501 gccttttcca aggctatggg aacgggcatt agcaagctcg gttttcagga tttggaagta
    28561 ttgaacaatg aacgtggggc gccttatttt agtcaggcac cattttcagg aaagatttgg
    28621 ctgtctatca gccacaccga tcagtttgtg acagccagtg tcattttgga ggaaaatcat
    28681 gaaagctagt ccacatagac caaccaaggc tctgattcat ctgggagcta ttcgacaaaa
    28741 tattcagcaa atgggggctc atatccctca aggaacgctc aagttggctg tggttaaggc
    28801 caatgcttat ggtcatggag ctgttgccgt tgccaaggca attcaagatg atgttgatgg
    28861 cttttgcgtt tccaatatcg atgaagccat tgaactcaga caagctggac tcagcaagcc
    28921 aatcctcatt ttaggagttt ctgaaatcga agctgttgct ctagctaaag aatatgactt
    28981 caccttgaca gtggctggac tggagtggat tcaagcactc ttagataagg aagtggacct
    29041 aactggattg acagtccacc tcaagattga ttcagggatg ggacggattg gttttagaga
    29101 ggcaagtgag gttgagcagg ctcaagattt gctccaacaa cacggtgttc gtgttgaagg
    29161 aatctttacc cactttgcta ctgctgatga ggaatcagat gactatttta atgcccagtt
    29221 agaacggttt aaaactattt tagctagtat gaaggaagtt ccagagctgg ttcatgctag
    29281 caattctgca acgactcttt ggcatgtaga gactattttc aatgcggttc gtatgggaga
    29341 tgccatgtat ggtctcaatc caagtggagc ggtcttggct ttgccttatg atttgatacc
    29401 ggccttgacc ttggagtctg ctctggttca tatcaagaca gttccagctg gtgcttgcat
    29461 gggctatgga gcaacttatc aaacggatag cgagcaagtc atcgcgaccg tgccaatcgg
    29521 gtatgcagat ggatggacaa gagacatgca aaatttctct gtcttggtag atggccaagc
    29581 ttgcccaatt gtcggcaggg tttcgatgga ccaaatcact attcgattgc ctaagcctta
    29641 cccactcgga accaaggtaa ccttgattgg ctccaatggg gataaggaaa tcactgcaac
    29701 tcaggtagcg acctaccgcg taaccattaa ctatgaggtg gtttgcctcc tcagcgaccg
    29761 tattccgaga gaatattact agaaaagaaa ggagtggagc atgaatctac atcaaccctt
    29821 gcatgtcttg cctggtgtgg gaccaaagtc agcagaaaaa tacgccaaac taggaattga
    29881 aaacttgcaa gatctcttgc tctactttcc tttccgttat gaagacttca aaatcaagca
    29941 ggtgctggag ctggaagacg gtgagaaggc agttctttct ggtcaggtag tgactcctgc
    30001 tagtgtccag tattatggtt tcaagcgcaa tcgcctgcgt tttagtctca agcagggaga
    30061 ggtcgttttt gcggtgaatt tctttaacca gccctatctg gctgataaaa tagagttggg
    30121 agcaaccctt gctgtctttg gaaaatggga ccgcgctaag gctagtctga ctgggatgaa
    30181 ggttctggct caggtagaag atgacctcca gcctgtctat cgtctggctc agggaatcag
    30241 tcaggccagt ctggttaagg tcatcaagac ggcttttgat cagggactgg acctcttgat
    30301 agaagaaaat ctgccccagt ctttactaga caaatacaaa ctcatgtccc gttgtcaggc
    30361 agtccgagct atgcattttc caaaggattt ggcagaatac aagcaggctc ttcgccgtat
    30421 caagtttgag gaactctttt atttccaaat gcagctgcag atgctcaagt ctgaaaatag
    30481 agttcaggga agtggtctgg ttctgaattg gtctcaggaa aaagtgacag cagttaaagt
    30541 aagtcttcct tttgccctga cccaagctca ggaaaagagt ttgcaggaaa ttttaactga
    30601 tatgaagtcc gaccaccaca tgaatcgtct cctacaaggg gatgtgggga gtggaaaaac
    30661 ggtagtcgct ggcttggcca tgtttgcggc agtgacagca ggttatcagg ctgccctaat
    30721 ggtaccaaca gaaatcctcg cagagcaaca ctttgagagt ttacagaacc tttttcccaa
    30781 tttgaaactg gctctcttga caggttcctt gaaagctgca gaaaagagag aggtcttgga
    30841 gaccattgcc aagggtgagg ctgatttgat tatcggaact cacgctctga tacaagatgg
    30901 ggtggagtat gctcgtcttg gtttgattat tatcgatgag cagcaccgtt ttggtgtagg
    30961 gcaaaggcgt attttacggg aaaaaggtga caatccagat gtcctcatga tgacggcgac
    31021 tcccattcca cggacgcttg ccatcacagc ctttggagat atggatgttt ccattatcga
    31081 ccagatgcca gcaggtcgga agcctattgt gacgcgctgg atcaaacatg agcaactacc
    31141 tcaggtcttg acttggttag agggggaaat tcaaaaaggt tcccaagcct atgtcatctc
    31201 tcctttgatt gaagaatcag aagctctaga tttgaaaaat gccattgcct tatcagagga
    31261 gttgacgact cattttgcag gcaaggcaga ggtggctctt ctacatggta ggatgaagag
    31321 tgacgaaaaa gaccagatca tgcaggattt caaggagaga aagacggata ttctggtttc
    31381 gacgacggtt attgaggttg gggtcaacgt tcccaatgcg actgtcatga ttatcatgga
    31441 tgccgatcgc ttcggtctca gtcaacttca ccagcttaga ggtcgtgtcg gtcgggggga
    31501 caagcagtcc tacgctgttc tcgttgccaa tcccaagacg gattctggga aagaccgcat
    31561 gcgtatcatg acagaaacga ccaatggatt tgtccttgcg gaggaagatt tgaaaatgcg
    31621 tggttctggt gagatttttg gaaccagaca gtcaggactt ccagagttcc aagtggctga
    31681 tattatcgaa gattttccga ttttagaaga agcaagaaag gttgctagct acattagttc
    31741 tatagaagct tggcaagaag atccagagtg gcgcatgatt gcccttcatc tggaaaagaa
    31801 agaacatctg gattaagctt tctctaagga aaacttaagc tagtttttag gtttggctct
    31861 tatactaaag tcatcaaaaa gaaacgagga ctctcatatg acagtaacga ttaaagtaaa
    31921 ttaccaaacc actttccaaa agaaggaagc aaaaaactag tataaacaga agagagagcg
    31981 aaatgctctt tttcgtttct aaaactactt tcagcccatc atcctaaaag taaagaatct
    32041 aaattcactt tctatttatc cttctttctt gcattgatta catagatatg ctacagttgt
    32101 ggtaacgatt acaaaataaa aggagcatgc tatgaaaaat ccagctttgc tagaagaaat
    32161 taagacctat agaggaaggg atgaggttcc ggaagacttt gatgctttct gggatgggga
    32221 agtgaaaaat gtttccacgc ttccatccta ccacttggag gaaagagatt tccacattcc
    32281 tcaagtcaag tgctatgagt taacatttga aggaagcaag gaaggaaagg tctatgcacg
    32341 cattgttctt ccaaagagtg aggagaaggt tccactaatc ttccattttc atggttatat
    32401 gggacgtggc tgggactggg ccgacatgct gggcttcacc gtagctggtt acggtgttgt
    32461 ttccatggat gtgcggggcc agtcaggtta ctcacaagac ggcttgcgtt ctcctttagg
    32521 aaataccgtg aaggggcata ttatccgtgg tgctatggaa ggtcgggacc acctctttta
    32581 taaggatgtt tatctggata tttaccagtt ggtcgaaatt gttgctagtc tgtctcaggt
    32641 tgatgagaag cgtctttcta gctatggtgc ctcacaagga ggggctctag ctctagttgc
    32701 agcagcgctc aatcctcgaa ttcagaaaac agttgccatt tatcccttct tgtcagactt
    32761 cagacgggtg attgagattg gtaatactag cgaggcttac gacgaacttt tccgttattt
    32821 caagtttcac gaccccttcc atgaaacaga ggaggaaatc atggcgaccc ttgcctatat
    32881 cgatgtcaaa aatcttgccc atcgtatcca aggtgaggtt aagatgatta cgggcttgga
    32941 cgacgatgtt tgctatccca ttacccagtt tgcgatttat aatcgtctga cctgcgataa
    33001 aacctatcgc atcatgcctg agtatgctca cgaagccatg aatgtatttg tcaatgacca
    33061 agtctacaac tggctctgtg gaagtgagat tccttttaaa tatctaaaat aaggagtcga
    33121 ctctaagcac aaaatcttaa aaattacaaa cacgcatagt atcaggggat taaaaaaact
    33181 tgatactatg cgttttatca tggaaatata gtaaaatgaa acaagaatag gacaaaacga
    33241 tcaggacagt caaatcgatt tctaacaatg ttttagaagc aaatgtgtac tattctagtt
    33301 tcaatctatt atatttatag aattttttgt tgctagattt gtcaaattgc ttaaaataat
    33361 ttttttcaga aagcaaaagc cgatacctat cgagtagggt agttcttgct atcgtcaggc
    33421 ttgtctgtag gtgttaatac ttttcaaaaa tctctttaaa ccacgtcagc ttcgccttgc
    33481 cgtatatatg ttactgactt cgtcagttct atctgccacc tcaaaacggt gttttgagct
    33541 gactttgtca gtcttatcta caacctcaaa acagtgtttt gagcatcatg cggctagctt
    33601 cttagtttgc tctttgattt tcattgagta taaaaacaga tgagtttctg ttttcttttt
    33661 atggactata aatgttcagc tgaaactact ttcaaggaca ttattatata aaagaatttt
    33721 ttgaaactaa aatctactat attacactat attgaaagcg ttttaaaaat gaggtataat
    33781 aaatttacta acgcttataa aaagtgatag aatctatctt tatgtatatt taaagataga
    33841 ttgctgtaaa aatagtagta gctatgcgaa ataacagata gagagaaggg attgaagctt
    33901 agaaaagggg aataatatga tatttaaggc attcaagaca aaaaagcaga gaaaaagaca
    33961 agttgaacta cttttgacag tttttttcga cagttttctg attgatttat ttcttcactt
    34021 atttgggatt gtccccttta agctggataa gattctgatt gtgagcttga ttatatttcc
    34081 cattatttct acaagtattt atgcttatga aaagctattt gaaaaagtgt tcgataagga
    34141 ttgagcagga agtatggtat aaatagcata agctgatgtc catcatttgc ttataaagag
    34201 atattttagt ttaattgcag cggtgtcctg gtagataaac tagattggca ggagtctgat
    34261 tggagaaagg agaggggaaa attggcacca atttgagata gtttgtttag ttcatttttg
    34321 tcatttaaat gaactgtagt aaaagaaagt taataaaaga caaactaagt gcattttctg
    34381 gagtaaatgt cttatttcag aaatcgggat atagatatag agaggatcag tatgaatcgg
    34441 agtgttcaag aacgtaagtg tcgttatagc attaggaaac tatcggtagg agcggtttct
    34501 atgattgtag gagcagtggt atttggaacg tctcctgttt tagctcaaga aggggcaagt
    34561 gagcaacctc tggcaaatga aactcaactt tcgggggaga gctcaaccct aactgataca
    34621 gaaaagagcc agccttcttc agagactgaa ctttctggca ataagcaaga acaagaaagg
    34681 aaagataagc aagaagaaaa aattccaaga gattactatg cacgagattt ggaaaatgtc
    34741 gaaacagtga tagaaaaaga agatgttgaa accaatgctt caaatggtca gagagttgat
    34801 ttatcaagtg aactagataa actaaagaaa cttgaaaacg caacagttca catggagttt
    34861 aagccagatg ccaaggctcc agcattctat aatctctttt ctgtgtcaag tgctactaaa
    34921 aaagatgagt acttcactat ggcagtttac aataatactg ctactctaga ggggcgtggt
    34981 tcggatggga aacagtttta caataattac aacgatgcac ccttaaaagt taaaccaggt
    35041 cagtggaatt ctgtgacttt cacagttgaa aaaccgacag cagaattgcc aaatggtcga
    35101 gttcgcctgt atgttaatgg tgttttatct cgaacaagtc tgaaatctgg caatttcatt
    35161 aaagatatgc cagatgtaac gcatgtgcaa atcggagcaa ccaagcgtgc caacaatacg
    35221 gtttgggggt caaatctaca gattcggaat ctcactgtgt ataatcgtgc tttaacacca
    35281 gaagaggtac aaaaacgtag tcaacttttt aaacgctcag atttagaaaa aaaactacct
    35341 gaaggagcgg ctttaacaga gaaaacggac atattcgaaa gcgggcgtaa cggtaaacca
    35401 aataaagatg gaatcaagag ttatcgtatt ccagcacttc tcaagacaga taaaggaact
    35461 ttgatcgcag gtgcagatga acgccgtctc cattcgagtg actggggtga tatcggtatg
    35521 gtcatcagac gtagtgaaga taatggtaaa acttggggta accgagtaac cattaccaac
    35581 ttacgtgaca atccaaaagc ttctgaccca tcgatcggtt caccagtgaa tatcgatatg
    35641 gtgttggttc aagatcctga aaccaaacga atcttttcta tctatgacat gttcccagaa
    35701 gggaagggaa tctttggaat gtcttcacaa aaagaagaag cctacaaaaa aatcgatgga
    35761 aaaacctatc aaatcctcta tcgtgaagga gaaaagggag cttataccat tcgagaaaat
    35821 ggtactgtct atacaccaga tggtaaggcg acagactatc gcgttgttgt agatcctgtt
    35881 aaaccagcct atagcgacaa gggtgatcta tacaagggta accaattact aggcaatatc
    35941 tacttcacaa caaacaaaac ttctccattt agaattgcca aggatagcta tctatggatg
    36001 tcctacagtg atgacgacgg gaagacatgg tcagcgcctc aagatattac tccgatggtc
    36061 aaagccgatt ggatgaaatt cttgggtgta ggtcctggaa caggaattgt acttcggaat
    36121 gggcctcaca agggacggat tttgataccg gtttatacga ctaataatgt atctcactta
    36181 aatggctcgc aatcttctcg tgtcatctat tcagatgatc atggaaaaac ttggcatgct
    36241 ggagaagcgg tcaacgataa ccgtcaggta gacggtcaaa agatccactc ttctacgatg
    36301 aacaatagac gtgcgcaaaa tacagaatca acggtggtac aactaaacaa tggagatgtt
    36361 aaactcttta tgcgtggttt gactggagat cttcaggttg ctacaagtaa agacggagga
    36421 gtgacttggg agaaggatat caaacgttat ccacaggtta aagatgtcta tgttcaaatg
    36481 tctgctatcc atacgatgca taatggaaaa gaatacatta tcctcagcaa tgcaggtgga
    36541 ccgaatcgtg aaaatgggat ggtccacttg gcacgtgtcg aagaaaatgg tgagttgact
    36601 tggctcaaac acaatccaat tcaaaaagga gagtttgcct ataattcgct ccaagaatta
    36661 ggaaatgggg agtatggcat cttgtatgaa catactgaaa aaggacaaaa tgcctatacc
    36721 ctatcattta gaaaatttaa ttgggaattt ttgagcaaag atctgatttc tcctaccgaa
    36781 gcgaaagtga agcgaactag agagatgggc aaaggagaga tgggcaaagg agttattggc
    36841 ttggagtttg actcagaagt attggtcaac aaggctccaa cccttcaatt ggcaaatggt
    36901 aaaacagcga ctttcctaac ccagtatgat agcaaaacct tgttgtttgc agtagataag
    36961 gaagatatcg gacaggaaat tattggtata gctaaaggaa gcatcgaaag tatgcataat
    37021 cttcctgtaa atctagcagg tgccagagtt cctggcggag taaatggtag caaagcagcg
    37081 gtgcatgaag ttccagaatt tacaggggga gttaatggta cagagccagc tgttcatgaa
    37141 atcgcagagt ataagggatc tgattcgctt gtaactctta ctacaaaaga agattatact
    37201 tacaaagctc ctcttgctca gcaggcactt cctgaaacag gaaacaagga gagtgacctc
    37261 ctagcttcac taggactaac agctttcttc cttggtctgt ttacgctagg gaaaaagaga
    37321 gaacaataag agaagaattc taaacatttg attttgtaaa aatagaagga gatagcaggt
    37381 tttcaagcct gctatctttt tttgatgaca ttcaggctga tacgaaatca taagaggtct
    37441 gaaactactt tcagagtagt ctgttctata aaatatagta gattgaaata agatgtgaac
    37501 aactctatca ggaaagtcaa attaatttat agaaaaattt tagcagtcaa ggtgtactgt
    37561 tatagattca atatattatg tgactattaa ccttctcttc tcctaaaatt gactttcttg
    37621 ttttcttatc ttgtccactc gaaacaagta ttgtaagaat ttgattattt ttgaaagtac
    37681 ttttaatata cttgatatag ttaaaaaaga tttgaaacta aattccaaat tagaaaaaga
    37741 cttgaaat
//
LOCUS       DAVBCA010000015        37667 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.015, whole genome shotgun sequence.
ACCESSION   DAVBCA010000015 DAVBCA010000000
VERSION     DAVBCA010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37667)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37667)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37667
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.015"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            108..896
                     /gene="codY"
                     /locus_tag="VQU19_000700"
     CDS             108..896
                     /gene="codY"
                     /locus_tag="VQU19_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HET2479978.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            896..1471
                     /locus_tag="VQU19_000701"
     CDS             896..1471
                     /locus_tag="VQU19_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HET2479979.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDFFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            1553..1638
                     /locus_tag="VQU19_000702"
     tRNA            1553..1638
                     /locus_tag="VQU19_000702"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1587..1589,aa:Leu,seq:aag)
     gene            1921..3051
                     /gene="ugpC"
                     /locus_tag="VQU19_000703"
     CDS             1921..3051
                     /gene="ugpC"
                     /locus_tag="VQU19_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HET2479980.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFINVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            complement(3198..3344)
                     /locus_tag="VQU19_000704"
     CDS             complement(3198..3344)
                     /locus_tag="VQU19_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2479981.1"
                     /translation="MEIKEQTRKLAVSCSKYIFEVADKTDEISNHTYGKATLTWFEEI
                     FEEY"
     gene            3552..4310
                     /locus_tag="VQU19_000705"
     CDS             3552..4310
                     /locus_tag="VQU19_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HET2479982.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGLSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKVLTGEMTLMKLSGMIYDEGWLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            4397..4909
                     /locus_tag="VQU19_000706"
     CDS             4397..4909
                     /locus_tag="VQU19_000706"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HET2479983.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            5091..6035
                     /locus_tag="VQU19_000707"
     CDS             5091..6035
                     /locus_tag="VQU19_000707"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HET2479984.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            6044..6721
                     /locus_tag="VQU19_000708"
     CDS             6044..6721
                     /locus_tag="VQU19_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HET2479985.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVRSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFRN
                     AMDLWKD"
     gene            6819..7577
                     /locus_tag="VQU19_000709"
     CDS             6819..7577
                     /locus_tag="VQU19_000709"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HET2479986.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            7615..9120
                     /gene="lytC"
                     /locus_tag="VQU19_000710"
     CDS             7615..9120
                     /gene="lytC"
                     /locus_tag="VQU19_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HET2479987.1"
                     /translation="MSVTFFIGEERLKTKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSTEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMMQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDLN
                     VGWVHRDGKRYFFNNREEQVGTEHAKKIIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAESDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTGTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPHYSGKKGWQYTSSEYMKGIQGRVDVSVWY"
     gene            9616..10134
                     /locus_tag="VQU19_000711"
     CDS             9616..10134
                     /locus_tag="VQU19_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HET2479988.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
     gene            10264..10770
                     /locus_tag="VQU19_000712"
     CDS             10264..10770
                     /locus_tag="VQU19_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HET2479989.1"
                     /translation="MTKKIVAIWAQDEEGVIGKENRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQAQEKNLYIIGG
                     KQIFQAFEPYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            10972..12204
                     /gene="clpX"
                     /locus_tag="VQU19_000713"
     CDS             10972..12204
                     /gene="clpX"
                     /locus_tag="VQU19_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HET2479990.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            12213..12800
                     /locus_tag="VQU19_000714"
     CDS             12213..12800
                     /locus_tag="VQU19_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HET2479991.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            12811..13191
                     /locus_tag="VQU19_000715"
     CDS             12811..13191
                     /locus_tag="VQU19_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HET2479992.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            13243..14133
                     /gene="rapZ"
                     /locus_tag="VQU19_000716"
     CDS             13243..14133
                     /gene="rapZ"
                     /locus_tag="VQU19_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HET2479993.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLAQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            14130..15107
                     /locus_tag="VQU19_000717"
     CDS             14130..15107
                     /locus_tag="VQU19_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HET2479994.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            15104..16015
                     /gene="whiA"
                     /locus_tag="VQU19_000718"
     CDS             15104..16015
                     /gene="whiA"
                     /locus_tag="VQU19_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HET2479995.1"
                     /translation="MSFTVAVKEEILGQHHLSRHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLVNGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(16049..17017)
                     /locus_tag="VQU19_000719"
     CDS             complement(16049..17017)
                     /locus_tag="VQU19_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HET2479996.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWTLAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPSQLLGNGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            17153..18010
                     /locus_tag="VQU19_000720"
     CDS             17153..18010
                     /locus_tag="VQU19_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HET2479997.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            17997..18776
                     /locus_tag="VQU19_000721"
     CDS             17997..18776
                     /locus_tag="VQU19_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HET2479998.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            18800..20152
                     /locus_tag="VQU19_000722"
     CDS             18800..20152
                     /locus_tag="VQU19_000722"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HET2479999.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAIQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            20226..20600
                     /locus_tag="VQU19_000723"
     CDS             20226..20600
                     /locus_tag="VQU19_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HET2480000.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            20602..21450
                     /locus_tag="VQU19_000724"
     CDS             20602..21450
                     /locus_tag="VQU19_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET2480001.1"
                     /translation="MKLAVFTDSSAYLSEETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            21727..22494
                     /locus_tag="VQU19_000725"
     CDS             21727..22494
                     /locus_tag="VQU19_000725"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HET2480002.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDDMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            22506..23690
                     /locus_tag="VQU19_000726"
     CDS             22506..23690
                     /locus_tag="VQU19_000726"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HET2480003.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNPQAITEKYQ
                     SLTIHDKKEIQINGDILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            23687..25558
                     /locus_tag="VQU19_000727"
     CDS             23687..25558
                     /locus_tag="VQU19_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET2480004.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELDRAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQAVSFAYENKPILQD
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTKGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDSKIRPFFGHYTDYLDEKAFETDMANQVQKVEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(25701..26885)
                     /gene="mntE"
                     /locus_tag="VQU19_000728"
     CDS             complement(25701..26885)
                     /gene="mntE"
                     /locus_tag="VQU19_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HET2480005.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERF
                     GVFDTDVHIEPAPISEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            27189..29885
                     /locus_tag="VQU19_000729"
     CDS             27189..29885
                     /locus_tag="VQU19_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HET2480006.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            29898..30689
                     /gene="yghU"
                     /locus_tag="VQU19_000730"
     CDS             29898..30689
                     /gene="yghU"
                     /locus_tag="VQU19_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HET2480007.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTENVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            30805..31215
                     /locus_tag="VQU19_000731"
     CDS             30805..31215
                     /locus_tag="VQU19_000731"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HET2480008.1"
                     /translation="MEKKIVKDILFLSQVSHPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGMQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            31227..32822
                     /locus_tag="VQU19_000732"
     CDS             31227..32822
                     /locus_tag="VQU19_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480009.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPKSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTN
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESIKGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKVQ"
     gene            32989..33153
                     /locus_tag="VQU19_000733"
     CDS             32989..33153
                     /locus_tag="VQU19_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HET2480010.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            33232..33960
                     /gene="yaaA"
                     /locus_tag="VQU19_000734"
     CDS             33232..33960
                     /gene="yaaA"
                     /locus_tag="VQU19_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HET2480011.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQTVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(34011..35495)
                     /locus_tag="VQU19_000735"
     CDS             complement(34011..35495)
                     /locus_tag="VQU19_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003096885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET2480012.1"
                     /translation="MRNLLSTKVQRQLRLMETLIQNRNWMKLHELAEKLGCTERILKS
                     DLNELRIAFPSINIQSSVNGIMIDLEVNTSVEDIYQYFLANSQSFQLLEYMFFNEGLP
                     IYRTIENLYFSSANLYRLGRNITKVLSSQFQIELSFTPSEIRGNEIDIRYFFAQYFSE
                     RYYFLDWPFPDLPEEDLTEFADFFYKITNYPMRFSIYRMYKLMIAISIHRVKNGHFID
                     LPNHFYKEYYPLLKSIPNFQETLAYFSKHFGLEMTPDTIAQIFISFLQNDIFLDPQEF
                     FNSLEDNSQARYSYQLLSQILERLSKQYKITFTNHDELIWHLHNTAFFERQEIFSTPI
                     LFEQKALTIKKFEGYFPDFMGSARQELAQYRQAIGQHDHPEQLEHLMYTILTHAENLS
                     TQLLENRPPIKVLIISNFDHAISLTFVDMLSYYCNNRFTFDIWDELKTSPEILNQTDY
                     DIIVSNFYISGITKKFICRNHLSIMNLVNHLNTLSNEIHLSNTL"
     gene            35711..>37667
                     /locus_tag="VQU19_000736"
     CDS             35711..>37667
                     /locus_tag="VQU19_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET2480013.1"
                     /translation="MKHSHKKSFDWYSMQQRYSIRKYYFGAVSVLLGTALVLGAAASV
                     QTVQAEENKQETTNSISVGRGEAATKPAEVSASNKEKTYAAPTVANPVETTPVKTGEV
                     TKPAEKVEEAKDKKEEVTHQDAIDKSKLLTALSRAKKLESKLYTEASAANLQTSIQAG
                     QSLLGKADASEAELSAAESSIQSSIIGLELRSNSNKGTVSETPVAKKANIVEAKEETN
                     PAATTDRSAVDSAVLPTSTAAKVETTSAPASINEILKPGLSLSDARQNPAIRKEDVDR
                     GYSGFRAAPAPTNQPVTNLGNNTVFTDISRGSHTFRGNGNSRRGNPIHFDVTTTRVRN
                     RVDFSIRYSGPGEFVNNNFILDKGNGFGEPSRATVSTPKLRDQVKNISKGGNFVSHSG
                     YSLEAAVETSTNQTIKFSLPIANPNGDLSVRLRPVTFNVGQGESGSATSNDPYSNSNY
                     YFREKPLLLDANPNGGTNNKTVSEDIDFQTVYLPTSKLPEGQTRLVREGEKGQRQIIY
                     KVHQLGNETILGLPISNSVIKEVKPRIMQIGVAKDLIDTVKPRVDQNKVGDTNNLTFY
                     LDNDGNGVYTEGVDELVQKIAIKDGAKGEKGDRGERGLTGAQGAKGEKGDRGERGLTG
                     AQGAKGEKGDRGERGLTGAQGAKGEKGD"
BASE COUNT        11317 a         6899 c         8566 g        10885 t
ORIGIN      
        1 tttaattaaa ttgtaagtca atgcaagtca ataaggaatt ttcagataat tattgaaaaa
       61 gagacgtttt tatgttataa tgatagcgat taaattcgag gtgaaaaatg gcacatttat
      121 tagaaaaaac tagaaaaatt acatcaattt tgaaacgctc agaggagcag ttgcaggatg
      181 agctccctta caacgctatt acgcgtcagt tagcggatat tattcattgc aatgcctgca
      241 ttatcaatag taagggacgt ctgcttggct attttatgcg ttataaaaca aatacagatc
      301 gcgtagagca attcttccaa actaagattt tcccagatga ctacgttcaa ggggctaata
      361 tgatttacga aacagaagca aacttgcctg ttgagcatga tatgagtatt ttccctgttg
      421 agagtagaga tgattttcca gatggcttga cgactattgc accgattcat gtatcgggga
      481 ttcgccttgg ttctttgatt atttggcgta atgataaaaa attcgaagat gaggacttgg
      541 ttcttgttga gattgccagt accgttgttg ggattcagct tcttaacttc caacgtgaag
      601 aagatgagaa aaatattcgt cgtcgtactg ctgtcaccat ggcggtcaat accctttctt
      661 actccgaact ccgtgctgtt tcagcaattt taggggaatt aaatggaaat gaagggaagt
      721 tgactgcgtc agtgattgca gatcgtatcg gaatcactcg ctctgtgatt gtcaatgctc
      781 ttcgtaaact tgagtctgcg gggattattg aaagtcgctc acttggaatg aagggaacct
      841 atcttaaggt cttgatttca gatatttttg aagaagtgaa gaaaagagat tactaatgac
      901 aaaggcttta atttcgattg attatacaga agattttgtt gctgatagtg ggaagctgac
      961 agcaggtgct ccagctcagg cgatttcgga tgccatcagc aaggtaactc gattagcttt
     1021 tgaacgagga gattatatct tctttactat tgatgctcat gaagaaaacg attttttcca
     1081 tccggaaagt aagttatttc ctcctcataa tctgattggg acgagtggac ggaatttata
     1141 tggagatttg gggatctttt atcaagagca tggttcagac agtcgtgtct tttggatgga
     1201 taaacgccat tactcagctt tttcagggac tgacctagat attcgtttga gagagcgtag
     1261 agtgtctacc gttatcttaa caggtgtctt gacggatatc tgtgtcctac atacagctat
     1321 agatgcctat aatctaggat atgacatcga gattgttaaa ccagctgttg cttccatctg
     1381 gcctgaaaat catcaatttg ccctaggtca tttcaaaaat acactcggag ctaagttagt
     1441 agatgaaaat ctaaatgaac tttctgagta acctggttgg tgaaaatgaa aaaatttgaa
     1501 aaaaagtgtt gacaagcatc ccaaaagttg atatactagt aaagtaatcg atgcggggat
     1561 ggcggaattg gcagacgcgc aggactaagg atcctgtgac cgctttaggt cgtgagggtt
     1621 caagtccctc tctccgcata ggaaaagagt tagctaaagc tagctctttt gtatttctct
     1681 aaaaaattag aatccagtca aatgtagtgg agaatcagcg aaaatatggg aaaactgttc
     1741 cttgtttctg cttttgtcat agaagaataa taaagattat cttcttcaaa ttctccgata
     1801 ttctctaaag ttttgtgcaa gttgcacaga acttttttat ttttttggtc atcttgccat
     1861 agaaatataa agcgttttca tctataatat aattatcaaa agacaaaagg agttcacctc
     1921 atggtagaat tgaatcttaa aaatatttac aaaaaatatc caaacagcga acactattca
     1981 gttgaagatt tcaacttgaa catcaaagat aaagaattta tcgttttcgt aggaccttca
     2041 ggatgtggta aatcaactac actccgtatg attgctggtc ttgaagacat tacagaaggt
     2101 actgcatcta tcgatggcgt ggttgtcaac gacgtagctc caaaagaccg tgatatcgcc
     2161 atggtattcc aaaactacgc tctttaccca cacatgactg tttatgacaa catggctttc
     2221 ggtttgaaat tgcgtaaata cagcaaagaa gacattaaca aacgtgttca agaagcagct
     2281 gaaatacttg gattgaaaga attcttggaa cgtaaaccag ctgacctttc aggtggtcaa
     2341 cgtcaacgtg ttgccatggg gcgtgcgatt gtccgtgatg cgaaagtatt cttgatggac
     2401 gaacctttgt caaacttgga tgccaaactt cgtgtatcaa tgcgtgctga aatcgctaaa
     2461 attcaccgtc gtatcggagc tacaactatc tatgtaactc acgaccaaac agaagcgatg
     2521 acacttgcag accgtatcgt tattatgtca gctactaaga accctgctgg tacaggtact
     2581 atcggacgtg tagaacaaat cggtactcct caagaagttt acaaaaatcc agttaacaaa
     2641 ttcgttgcag gattcatcgg aagcccagct atgaacttca tcaacgtgaa attggttggt
     2701 agcgaaattg tttctgacgg tttccgtttg aaagtgccag aaggagcatt gaaagttctt
     2761 cgtgaaaaag gctacgaagg aaaagaattg atctttggta tccgtccaga agacgtgaat
     2821 gcagaacctg ctttccttga aacattccca gactgtgttg taaaagcgac tatctctgta
     2881 tcagaactgc ttggttcaga atctcacctt tactgccaag ttggtaaaga cgagtttgtt
     2941 gcaaaagttg atgctcgtga ctacttgcaa acaggtgcaa cagttgagct tggatttgac
     3001 ttgaacaaag cacacttctt cgatgtagaa actgaaaaaa caatctacta aaataaataa
     3061 aattcaaagc actacaagaa aagatatctc tttatcaatt gtagtggaga gatatcagtt
     3121 aatctaggga gagaaacaaa atgcttctct cctttttgct agggaagtca tattatgcat
     3181 ctatattgtg atgctcttta atactcttcg aaaatctctt caaaccacgt caacgtcgcc
     3241 ttgccgtacg tatgattact gatttcgtca gttttatctg caacctcaaa gatgtacttt
     3301 gagcagctta cggctagttt cctagtttgc tctttgattt ccattgagta ttatttgtgg
     3361 gtaccatcta caagtgaagc tatatgcgta aactacgtga gcaattgaat tcgaactaga
     3421 gaggtaataa taaatttatg ctatagttat ggtgacttgt atgcttttga ttctagttta
     3481 tcaaataata gattagaatt gtcagataat atcattttgt gttataatga agaaaaaaca
     3541 gaggtgttca aatgtcagaa gcaggtcata agtttttagc aaaattgggg aaaaaacgct
     3601 tacgtccagg tggaaagcgt gctacagatt ggttaattgc agaaggagga ttgtcaaaag
     3661 aaaagagaat actagaggtt gcgtgtaata ggggaactac agcaattgag ttggcacagc
     3721 gttttggttg caagataact gctgttgata tggatgctca agctttagaa gtggctaaaa
     3781 aatctgctgg aacggcaggt gttgctcatt taatcagttt tgaaagagca aatgcaatga
     3841 aacttcctta tcaagatgct agttttgata ttgttataaa tgaagctatg ctgactatgc
     3901 aagccgatca agctaagaaa aaatgtgtaa tggaatatct aagggtatta aaacctggag
     3961 gtcttctttt gacacatgat gtgcttctta aggaagctaa agagtctatc agacaggaat
     4021 tatcacaagc aattcatgta aatgtaggtc ctttaactca agatggttgg gaacaggtga
     4081 tgatagaatc aggttattgt gatgtgaaag tattgactgg tgaaatgaca ttaatgaaat
     4141 tatcgggtat gatttatgac gaaggttggc taggaacttt gaaaatttgt gtaaatgctt
     4201 gtaaaaagga gaatagaaag cagtttttaa ctatgtataa aatgtttgct aagaataaac
     4261 agaaattggg ctttattgcg atggctagtt ataaatcgtc aaaacgttag ataattattg
     4321 aagttaactt ttcctttttt ctttcttaaa aaatatgcta taatagagag tgaaaaactt
     4381 tgaaagaaag aaaaagatga atttaaaaga ttacattgca acaattgaaa attatccaaa
     4441 ggaaggcatt accttccgtg atattagtcc tttgatggct gatggaaatg cttatagcta
     4501 cgctgttcgt gaaatcgttc agtatgctac tgacaagaaa gtcgacatga tcgtgggacc
     4561 tgaagctcgt ggatttatcg tgggttgtcc agttgccttt gagttgggaa ttggttttgc
     4621 gcctgttcgt aagccaggta aattgccacg cgaagttatt tctgctgact atgaaaaaga
     4681 gtacggtgtc gataccttga ctatgcacgc ggatgccatt aagccaggtc aacgtgttct
     4741 tattgtagat gaccttttgg cgacaggtgg aactgttaag gcaactatcg agatgattga
     4801 aaaacttggt ggtgttatgg caggttgtgc cttccttgtt gaattggatg aattgaacgg
     4861 ccgtgaaaaa atcggtgact acgactacaa agttcttatg cattattaat gaaaacagtc
     4921 cctagggctg ttttctctac actaggatat aaaaatagac tataactagt tagagaaaaa
     4981 ctataattga aaactatatc ttcttgcagt ataataaaag gactaagtgt ttgagatttg
     5041 tcttcaaaca catgcaatta ttcctgagag agtacagtta ggagagggtt atgccgattc
     5101 gaattgataa aaaattgcca gctgttgaga ttttacggac agagaatatc tttgtcatgg
     5161 atgatcaacg tgctgcccac caagatatcc gtcctttgaa gattttaatt ttaaatctca
     5221 tgccacagaa aatggtcaca gagacccagt tgttgcgtca cttggctaat acacccctac
     5281 aactggatat tgattttctc tatatggaga gccaccgttc taaaacaact cgttcagagc
     5341 acatggagac cttctataaa acttttcctg aagtcaagga tgagtatttt gatgggatga
     5401 tcatcacggg tgctccagtt gagcatttac catttgagga agtggactat tgggaggaat
     5461 ttaggcagat gcttgagtgg tctaagacac atgtctattc gacccttcat atctgttggg
     5521 gggctcaggc tgggctttat ctgcgctatg gtgtagaaaa ataccagatg gacagtaagc
     5581 tatcaggtat ttatcctcag gacaccctaa aagagggtca ccttctattt agaggctttg
     5641 atgatagcta tgtatcccct cattcacggc acacggagat ttctaaggaa gaggtcttaa
     5701 acaagaccaa tctcgagatt ttatcagaag gacctcaggt tggggtttct attttggcca
     5761 gtcgtgattt acgagaaatt tatagttttg gtcatttgga gtatgaccgt gataccttgg
     5821 caaaagagta ttttcgagat cgtgatgcag gtttcgaccc acatattcca gaaaattact
     5881 ttaaagatga tgatgttaat caggtacctt gtctttgttg gtcttcatct gcagccctct
     5941 ttttcagtaa ttgggtaaac catgcggtct atcaggagac gccttttgat tggagaaaga
     6001 tagaagatga tgcatctgca tatgggtatt tataagagga attatgacat atttagacgc
     6061 ttttaaatca ggtaccttgg ttttaccgag tgccctgctc ttgcatttta aggaactctt
     6121 tccttctagc gacgattttc tggtttggca atttttctat ttgcaaaata cgacaggctt
     6181 agaagaaatg tcgccaagcc agattgctga aaggattggc aaggaaattt cggatgtcaa
     6241 ccagtccatt tctaatctga cggaaagggg actgctccag tatcgtacta tcgaattaaa
     6301 tggcgaaatt gaattgctct ttgatgctag tttggccttg gaacgtttgg atgacctgtt
     6361 tggagcagtt cgttcaagtt cagaccagct aacacctcaa aaccagctca aggatttggt
     6421 ggaaaccttc cagcaggagt tgggacgatt gttgacgcct tttgagattg aggatttgac
     6481 caagacacta aaggaagatg gaaccagtgc tgacttgatt aaggaggctc ttcgtgaagc
     6541 tgttttgaat ggaaaaccaa actggaagta cattcaggcg attttgagaa actggcgcca
     6601 tgaaggaatc aagagtgtgg ctcaaattga ggccaagaga gcagaaagag aagcaagcaa
     6661 tcctcagttg acacaggtat ctgcagattt cagaaatgcc atggatctct ggaaggatta
     6721 atccatgcaa gtaggcttga aatccgagta agatttgcaa gctgtgtata attgtgatag
     6781 aataaataga aaataaattg aaaaaagagg tatgtgaaat gtcacgtaaa ccatttatcg
     6841 ctggtaactg gaaaatgaac aaaaatccag aagaagctaa agcattcgtt gaagcagttg
     6901 catcaaaact tccttcatca gatcttgttg aagcaggtat cgctgctcca gctcttgatt
     6961 tgacaactgt tcttgctgtt gcaaaaggct caaaccttaa agttgctgct caaaactgct
     7021 actttgaaaa tgcaggtgct ttcactggtg aaactagccc acaagttttg aaagaaatcg
     7081 gtactgatta cgttgttatc ggtcactcag aacgccgtga ctacttccat gaaactgacg
     7141 aagatatcaa caaaaaagca aaagcaatct ttgcgaacgg tatgcttcca atcatctgtt
     7201 gtggtgaatc acttgaaact tacgaagctg gtaaagctgc tgaattcgta ggtgctcaag
     7261 tatctgctgc attggctgga ttgactgctg aacaagttgc tgcctcagtt atcgcttatg
     7321 agccaatctg ggctatcggt actggtaaat cagcttcaca agacgatgca caaaaaatgt
     7381 gtaaagttgt tcgtgacgtt gtagctgctg actttggtca agaagtcgca gacaaagttc
     7441 gtgttcaata cggtggttct gttaaacctg aaaatgttgc ttcatacatg gcttgcccag
     7501 acgttgacgg tgcccttgta ggtggtgcgt cacttgaagc tgaaagcttc ttggctttgc
     7561 ttgactttgt aaaataatca gtaagtagca aaagctaggt ggaacagcat tcagatgtct
     7621 gttacatttt ttataggaga ggaaagattg aaaacaaaaa ttggattagc aagtatctgt
     7681 ttactaggct tggcaactag tcatgtcgct gcaaatgaaa ctgaagtagc aaaaacttcg
     7741 caggatacaa cgacagcttc aagtagttca gagcaaaatc agtcttctaa taaaacgcaa
     7801 acgagcacag aagtacagac taatgctgct gcccactggg atggggatta ttatgtaaag
     7861 gatgatggct ctaaagctca aagtgaatgg atttttgaca actactataa ggcctggttt
     7921 tatattaatt cagatggtcg ttactcgcag aatgaatggc atggaaatta ctacctgaaa
     7981 tcaggtggat atatggccca aaacgagtgg atctatgaca gtaattacaa gagttggttt
     8041 tatctcaagt cagatggggc ttatgctcat caagaatggc aattgattgg aaataagtgg
     8101 tactacttca agaagtgggg ttacatggct aaaagccaat ggcaaggaag ttatttcttg
     8161 aatggtcaag gagctatgat gcaaaatgaa tggctctatg atccagccta ttctgcttat
     8221 ttttatctaa aatccgatgg aacttatgct aaccaagagt ggcaaaaagt gggcggaaaa
     8281 tggtactatt tcaagaagtg gggctatatg gctcggaatg agtggcaagg caactactat
     8341 ttgactggaa gtggtgctat ggcgactgac gaagtgatta tggatggtgc tcgctatatc
     8401 tttgcggcct ctggtgagct caaagaaaag aaagatttga atgtcggctg ggttcacaga
     8461 gatggtaaac gctatttctt taataataga gaagaacaag tgggaaccga acatgctaag
     8521 aaaatcattg atattagtga gcacaatggt cgtatcaatg attggaaaaa ggttattgat
     8581 gagaacgagg tggatggtgt cattgttcgt ctaggttata gcggtaaaga agacaaggaa
     8641 ttggcgcata acattaagga gttaaaccgt ctgggaattc cttatggtgt ctatctctat
     8701 acctatgctg aaaatgagac cgatgctgag agtgacgcta aacagaccat tgaacttata
     8761 aagaaataca atatgaacct gtcttaccct atctattatg atgttgagaa ttgggaatat
     8821 gtaaataaga gcaagagagc tccaagtgat acaggcactt gggttaaaat catcaacaag
     8881 tacatggaca cgatgaagca ggcgggttat caaaatgtgt atgtctatag ctatcgtagt
     8941 ttattacaga cgcgtttaaa acacccagat attttaaaac atgtaaactg ggtagcggcc
     9001 tatacgaatg ctttagaatg ggaaaaccct cattattcag gaaaaaaagg ttggcaatat
     9061 acctcttctg aatacatgaa aggaatccaa gggcgcgtag atgtcagcgt ttggtattaa
     9121 gcgatgattt gaaagaggga tgtgatagta gcaccctctt tttctttgtt ttatgatagt
     9181 tcatcctcga gtaaattcaa gttcttgctc ggaaatgaag cttatatagt agattgaata
     9241 tagacaaata ccttgtgatt ggtaaaacat tttagaaatt catttacctt tcctaatcga
     9301 cttggtttca tcttatttca atctattata gtattgggga atttcttcaa accacatcag
     9361 cttggtcagt tctacctgcg acctcaaaac ttgtgctttg gtcaagctgg gtttagtttc
     9421 ctagtttgct gatggatttc cattgactat aagcatccaa ccctcttttt gtcttctaaa
     9481 gaattcttaa attatcagtc tattgcaact tttctcatat aagttctttg tcttgctatt
     9541 ggttttcctt agtagtatac taaggtagta atcattaaga agtggttaca aaaaataatg
     9601 aatgaggtaa agaaaatggt agaattgaaa aaagaagcag taaaagacgt aacatcattg
     9661 acaaaagcag cgccagtagc attggcaaaa acaaaggaag tcttgaacca agctgttgct
     9721 gatttgtatg tagctcacgt tgctttgcac caagtgcact ggtatatgca tggtcgtggt
     9781 ttccttgtat ggcatccaaa aatggatgag tacatggaag ctcttgacgg tcaattggat
     9841 gaaatcagtg aacgcttgat tacactcggt ggaagcccat tctctacatt gacagagttc
     9901 cttcaaaata gtgaaatcga agaagaagct ggtgaatacc gtaatgttga agaaagcttg
     9961 gaacgtgttc ttgttatcta ccgttacttg tcagaacttt tccaaaaagg tttggatgtc
    10021 actgatgaag aaggtgacga tgtgacaaac ggtatctttg caggcgctaa aactgaaaca
    10081 gataaaacaa tttggatgct tgcagccgaa cttggacaag cacctggttt gtaagaaata
    10141 aggaaacata gataaatctg taggaaattt cttacagatt ttttctattt tgtaagctat
    10201 tccaaaccag tctttttttg agttttttga taaaatagta ctatcagtga aaaggatgga
    10261 agcatgacta agaaaatcgt agctatttgg gcccaggatg aagagggtgt gattggtaag
    10321 gaaaatcgtc tgccttggca tttgccagca gaattgcagc actttaaaga aacaactctg
    10381 aatcatgcta tcttgatggg gcgtgtgacc tttgatggga tggggcgtcg cttgcttcca
    10441 aaacgggaaa ccttgatttt gacgcgtaat ccggaagaaa agatagatgg ggttgctact
    10501 tttcaggacg tccagtctgt tcttgactgg tatcaggctc aagaaaagaa tctctacatt
    10561 atcggtggga agcaaatttt tcaggctttt gaaccttacc ttgatgaagt gattgtcact
    10621 cacattcatg ctcgggtgga aggagatacc tatttccctg aagaacttga cttgtctctt
    10681 tttgagacag tttcaagcaa attttacgcc aaagatgaga agaatcctta tgattttacc
    10741 atccaatacc gcaagagaaa ggaagtctaa tggaacggag tttatttggt ctattcacgg
    10801 cttttctgtg tttcatctgc tttctggcag gagcacaagc ttttcgtaaa aagcgttacg
    10861 ggctttctat cctcctttgg ttaaatgcct ttaccaatct ggtcaatagt attcatgctt
    10921 tttacatgac cttattttag atagaatgac agtatagaat ggaaggaaat catgtctaca
    10981 aatagaaaaa atgatatgat ggtttattgc tcattttgtg gcaaaaacca agaagaagta
    11041 caaaaaataa ttgctggcaa caatgctttt atttgtaatg aatgcgtgga gttagctcag
    11101 gaaatcattc gagaagaatt ggttgaggaa gtcttggcag acttgtctga ggtgccaaaa
    11161 ccaattgaac tcctccatat cttgaaccac tatgtaattg gtcaagatcg tgccaagcgt
    11221 gccttggcag tggcggttta taaccactac aaacgcatca atttccacga tacacgcgaa
    11281 gagtcagaag atgtggattt gcagaagtca aacattttga tgattggccc aactggttca
    11341 gggaaaactt tccttgccca gaccttggct aagagcttga atgtaccttt tgctattgcg
    11401 gatgcgacag ctctgacgga ggctggttat gtgggtgagg atgtggaaaa tatactcctc
    11461 aaactcttgc aggttgctga ctttaacatc gaacgtgcag agcgtggcat tatctatgtg
    11521 gatgaaattg acaagattgc caagaagagt gagaatgtgt ctatcacacg tgatgtttct
    11581 ggtgaagggg tgcaacaagc ccttctcaag attattgagg gaactgttgc tagcgtaccg
    11641 cctcaaggtg gacgcaaaca tccacaacaa gagatgattc aagtggatac aaaaaatatc
    11701 ctcttcatcg tgggtggtgc ttttgatggt attgaagaaa ttgtcaaaca acgtctgggt
    11761 gaaaaagtca tcggatttgg tcaaaacaat aaggcgattg acgaaaacag ctcatacatg
    11821 caagaaatca tcgctgaaga cattcaaaaa tttggtatta tccctgagtt gattggacgc
    11881 ttgcctgttt ttgcggctct tgagcaattg accgttgatg acttggttcg catcttgaaa
    11941 gagccaagaa atgccttggt gaaacaatac caaaccttgc tttcttatga tgatgttgag
    12001 ttggaatttg acgacgaagc ccttcaagag attgctaata aagcaatcga acggaagaca
    12061 ggggcgcgtg gacttcgctc catcatcgaa gaaaccatgc tagatgttat gtttgaggtg
    12121 ccgagtcagg aaaatgtgaa attggttcgt atcactaaag aaactgtcga tggaacggat
    12181 aaaccgatcc tagaaacagc ctagaggtga ctatggaact taatacacac aatgctgaaa
    12241 tcttgctcag tgcagctaat aagtcccact atccgcagga tgaactgcca gagattgccc
    12301 tagcagggcg ttcaaatgtt ggtaaatcca gctttatcaa cactatgttg aaccgtaaga
    12361 atctcgcccg tacatcagga aaacctggta aaacccagct cctgaacttt tttaacattg
    12421 atgacaagat gcgctttgtg gatgtgcctg gttatggcta tgctcgtgtt tctaaaaagg
    12481 aacgtgaaaa gtgggggtgc atgattgagg agtacttaac gactcgggaa aatctccgtg
    12541 cggttgtcag tctagttgac cttcgtcatg acccgtcagc agatgatgtg cagatgtacg
    12601 aatttctcaa gtattatgag attccagtca tcattgtggc gaccaaggcg gacaagattc
    12661 ctcgtggtaa atggaacaag catgaatcag caatcaaaaa gaaattaaac tttgacccaa
    12721 gtgacgattt catcctcttt tcatctgtca gcaaggcagg gatggatgag gcttgggatg
    12781 caatcttaga aaaattgtga ggaaaagaaa atggcaaaaa caattcatac agataaggcc
    12841 ccaaaggcta tcggacccta tgttcaagga aaaatcgttg gcaacctttt gtttgctagc
    12901 ggtcaagttc ccctatcccc tgaaactggg gaaattgtag gagagaatat ccaagaacag
    12961 acagagcaag tcttgaaaaa catcggtgct attttggcag aagcaggaac agactttgac
    13021 catgttgtca aaacaacttg cttcttgagc gatatgaacg actttgttcc ttttaatgag
    13081 gtttaccaaa cggccttcaa agaggaattc ccagctcgtt cagctgtgga ggtagctcgt
    13141 cttcctcgtg atgtaaaagt cgaaattgaa gtcatcgcag agattggata agctagttga
    13201 agtttggtgt tgccaaactt cttttgatat aaggagaaaa agatgacaaa gaaacaactt
    13261 cacttggtga ttgtgacagg gatgagtggc gcagggaaaa ctgtagccat tcagtccttc
    13321 gaggatctag gttatttcac cattgataat atgccgccag ctctcttgcc taagtttttg
    13381 cagctggttg aaattaagga agataatcct aagttggctt tggtagtgga tatgcgtagc
    13441 cgttctttct tttcagagat tcaagctgtt ttggatgagt tggaaaatca agatggtttg
    13501 gatttcaaaa tcctcttttt ggatgcggct gataaggaat tggtcgctcg ttacaaggaa
    13561 accagacgga gtcacccact agcagcagac ggtcgtattt tagatggaat caagttggaa
    13621 cgtgaactct tggcaccttt gaaaaatatg agccaaaatg tggtggatac gactgaactc
    13681 actccacgtg aactgcgcaa aacccttgca gagcagtttt cagaccaaga acaagcccag
    13741 tctttccgta tcgaagtcat gtctttcgga tttaagtatg gaatcccgat tgatgcggac
    13801 ttggtctttg atgtccgttt cttgccaaat ccctattatc taccagaact gagaaaccaa
    13861 acgggtgtgg atgaacctgt ttatgattat gtcatgaacc atcctgagtc agaagacttt
    13921 tatcaacatt tattggcctt gattgagccg attctgccaa gttaccaaaa ggaaggtaag
    13981 tccgttttga ccattgctat gggatgtacg ggtggacaac accgtagtgt ggcatttgct
    14041 aaacgcttgg cgcaggactt atccaagaat tggtctgtta atgaagggca tcgcgacaaa
    14101 gaccgcagaa aggaaacggt aaaccgttca tgagaaaacc aaagataacg gtgattggtg
    14161 gagggactgg aattcccgtc attctaaaaa gtctgcggga aaaagatgtg gaaatcgcag
    14221 ctatcgtgac ggtggcagat gatggtggtt cttcaggtga actccgaaaa aatatgcaac
    14281 agttgacacc gccaggtgat cttcgtaatg tccttgtggc catgtcggat atgcctaagt
    14341 tttatgagaa ggtctttcag tatcggttct ctgaggatgc cggagccttt gctggccatc
    14401 cattgggaaa tctcatcatt gctggcttgt cagaaatgca gggttcaacc tataatgcca
    14461 tgcagttatt gagcaaattt ttccatacaa cagggaaaat ttatccttcc agtgaccatc
    14521 ctttgaccct tcatgcagtc tttcaggatg ggacagaagt ggctggagag agtcatattg
    14581 tagaccatcg aggcataatt gacaatgtct atgtgaccaa tgccctaaac gatgatacgc
    14641 ctctggccag ccgtcgagta gtgcagacca tccttgaaag tgacatgatt gtcctagggc
    14701 caggttccct ctttacctct attttgccca atatcgtgat taaggaaatt gggcgggctc
    14761 ttttggaaac taaggcagaa attgcctatg tctgcaatat catgacccaa cgtggggaga
    14821 cggaacactt tacagatagc gaccacgtgg aagtcttgca tcgtcacctt ggtcgccctt
    14881 ttatcgacac tgtcttggtg aatattgaaa aagtgcctca ggaatacatg aattccaacc
    14941 gttttgatga atacttggtg caagtggaac acgattttgt aggtctttgt aagcaagttt
    15001 cgcgcgtgat ttcatctaac ttccttcgtc tggaaaatgg cggtgccttc cacgatggag
    15061 atttgattgt ggacgagttg atgcgcatta tacaggtgaa aaaatgagtt tcacagtagc
    15121 agtaaaagaa gaaatcctgg gccaacacca tctgagccgg catgaattat ctgccattat
    15181 caaaatgtct ggtagcatcg gtctctcgac ttcgggcttg actttgtcag ttgtgacaga
    15241 aaatgccaaa ctggcccgtc acctctatga gtcctttctc catttctatg aaatcaaatc
    15301 tgaaattcgt caccaccaac ggagcaatct tcgcaagaat cgcgtctata ccgtttttac
    15361 agatgaaaag gtgcaggatt tgttaagtga tttgcacttg gcagactctt tctttggcct
    15421 ggaaacaggt attgatgagg cgattttatc ggatgaggaa gcaggtcgtg cctatctctg
    15481 tggcgctttc ttggtaaatg ggagcattcg tgaccctgag tcaggcaagt accagttgga
    15541 aatcagttct gtttatctgg accacgcgca aggaattgcc tcccttctcc aacagttttt
    15601 actggatgcc aaggtgcttg agcgcaagaa gggggctgtg acctatctcc agcgagcaga
    15661 agacattatg gacttcttga tagtaatcgg agccatgcag gcacgtgatg attttgagcg
    15721 ggttaagatt ttgcgagaaa cccgtaacga cctcaatcgg gctaataatg ccgagacagc
    15781 taatatcgct cggacagttt ctgccagcat gaagaccatt aacaatatca gtaaaataaa
    15841 agatatcatg ggcttagaaa atttgccagt agatttgcag gaagtggcgc aactgaggat
    15901 tcagcaccca gactactcta tccagcagtt agcagatagt ctcagcaccc ctctgaccaa
    15961 aagtggtgtc aatcacagac tcagaaaaat caataagata gcggatgaat tataaaacca
    16021 cgaatcctat gtgactcgtg gttctttttt ataaactggt agagtgtttt ggttgtactt
    16081 tttgttcagg gtcaatgtag ttgatagcgt tgttgacagc agttggagct tctccgaggc
    16141 ctgtcgcaat cagatcaatt tttccgtcat agtagcagca gtcaccgata gcatagatac
    16201 ctgcttggct ggattcctgt ttgctgttga cgataatctt gtgacggttg aggtcgagcc
    16261 cccagttttt aaggttaccg acagaagatt tgaaaccata gttgacaaag aggtggtcta
    16321 ggtcaatggt ttcagtttca tcagatttga cttttgtgat ttcaagttta tcaagtgttt
    16381 ttccatttcc aaggagttgg ctaggggcga atggtgtctt gatggttaca gatgattctt
    16441 gcaaggcttg aacactgtgt tccaaggcac ggaaattatc tctgcggtga acaagggtag
    16501 ttggtgcgat tttttcaaaa gccaaagtcc aatccacagc cgagtctccc ccaccaagaa
    16561 tcgtcacttt tttaccagcg tattgctgaa tgttagaaac gtggtagtgg atattttcat
    16621 agccctcaac cccttcaagt tccagcggac gtggtttgaa ggcaccgcca cccatagcga
    16681 tgataactgt tttagtcagg tgacttcctt tagaagttgt gatggcaaat tcttcttctt
    16741 gtttgtcaat ctcaagaacc gtttcattga gatgaatagg ggtatcaaat ccatttagct
    16801 gttcaatcaa gcggttagtc aactcttctc cagtcaggtt tgggaagcct ggtacgtcta
    16861 ggatttcctt ttcagggtag agaatagcag gttgtccacc tagctgggga agagagtcga
    16921 tgatttgaac cttggcttgg cgtaggtggg cataaaaggc tgcaaaaagc ccgacaggac
    16981 caccacccac aatggtaata tcatagagtt gagacatagt ttctcctttg ttttttctag
    17041 tcagtttatt ttatcatatt tttgttcaat gtaaaatgga ctaggatagg gaaaaaaatg
    17101 ccagaaaatg gtataatagg acgaaagtgt tttgataggg aggatatcag ggatgaattt
    17161 tcaacaatta tccaatttgc aatattggac cagtttgttt gcaagtccat ggacgatagc
    17221 tatcaatctg attgatattt tgattgttgc ttatatttta taccatttta caaaagctat
    17281 tgcaggaacc aagattatga ttttggtacg tggagttttg gtatttattt tagctcaaat
    17341 ccttgcaaat atgattggtt tgactacgat ttcttggtta atcaatcaaa ttattactta
    17401 tggggttatt gcggcggttg ttatcttctc tccagagatt cggactggtt tggaacgttt
    17461 gggaagagcg acagatttct tttccaatgc ccctattagt gctgaggaac agatgattcg
    17521 tgcctttgtt aagtctgttg aatacatgag tcctcgtaaa atcggggcct tggttgctat
    17581 tcagcgtgta cgtaccttgc aggagtatat ttcgacagga attcccttgg atgctaagat
    17641 ttctgcagaa cttctcatta acatttttat tcccaacact cccctacatg acggtgcggt
    17701 gattatcaaa gaagaacgta tcgctgtgac gtctgcctat ctgcccttga caaaaaacac
    17761 agggatttcc aaggaatttg ggaccagaca ccgggcggct atcggtttat cagaagtctc
    17821 agatgccttg acttttgtcg tatcagagga aacgggagga atttcgataa cctataatgg
    17881 aaggtttaag cacaacctaa cacttgatga atttgaaaca gaattacgtg aaatcttact
    17941 tccaaaagag gaagtaggtc ttagttttaa agaacgattg ctaggaggat ggaaacatga
    18001 aaaaaaatag tttatatatc atatcctcac tcttttttgc ttgtgtctta tttgtctatg
    18061 ctacggcgac gaattttcaa aacagtacca gtgctaggca ggtaaaaacg gaaacctata
    18121 ctaatacagt aacaaatgtc cctattgaca tacgctataa tagtgataag tattttatta
    18181 gcggttttgc ttcagaagta tcagtggtct tgactggtgc aaatcgccta tcgctagcta
    18241 gtgaaatgca agaaagtaca cgtaaattca aggttactgc tgacctaaca gatgccggtg
    18301 ttggaacaat tgaagttcct ttgagcattg aagatttacc caatgggctg accgctgtgg
    18361 cgactccgca aaaaattaca gtcaagattg gtaagaaggc tcagaaggat aaggtaaaga
    18421 ttgtaccaga gattgaccct agtcaaattg atagtcgggt acaaattgaa aatgtcatgg
    18481 tgtcagataa agaagtgtcg attacgagtg accaagagac attggataga attgataaga
    18541 ttatcgctgt cttgccaact agcgaacgca taacaggtaa ttacagtggt tcagtacctt
    18601 tgcaggcaat cgaccgcaat ggtgttgtct taccggcagt tatcactccg tttgatacaa
    18661 taatgaaggt gactacaaaa ccagtagcac caagttcaag cacatcaaat tcaagtacaa
    18721 gcagttcatc ggagacatct tcgtcaacga aagcaactag ttcaaaaacg aattaaaaat
    18781 agaaaaggat tttataacaa tgggtaaata ttttgggact gatggagtcc gtggagaagc
    18841 taacctagaa ctaacaccag aattagcctt taaactagga cgttttggag gctatgttct
    18901 tagtcaacat gaaacggaag cgccgaaagt ctttgtagga cgtgacacac gtatttcagg
    18961 ggaaatgcta gaatcggcct tggtggcagg tctcctttca gtagggattc acgtatacaa
    19021 acttggtgtc cttgcaacac cagcagtagc ttacttggtt gaaactgaag gagcaagtgc
    19081 tggtgtcatg atttctgcta gccacaatcc agctcttgat aacggaatca agttctttgg
    19141 cggtgatggc ttcaaactag atgatgaaaa agaagcagaa attgaagcct tgctagatgc
    19201 tgaggaagac actcttcctc gtccaagtgc agaaggctta ggaattttgg tagattatcc
    19261 agaaggcttg cgtaagtatg aaggatacct tgtttcaact ggaactcctc ttgatggaat
    19321 gaaggttgcc ttggatacag ctaatggagc agcttctacc agtgcccgtc aaatctttgc
    19381 agaccttggt gcccaattga cggttatcgg ggaaacacca gacggtctta acatcaacct
    19441 taatgttggt tcaacacatc cagaagccct tcaagaagtg gtcaaagaaa gtgggtcagc
    19501 tattggtttg gcctttgatg gagacagtga ccgcttgatt gctgttgatg agaatggtga
    19561 catcgtcgat ggtgacaaga ttatgtacat catcggaaaa tacctttctg aaaaaggaca
    19621 attggctcaa aatacaattg tgacaactgt tatgtctaac cttggtttcc acaaggcctt
    19681 gaatcgcgaa ggtattaaca aggcagttac tgcagttggt gaccgctacg ttgttgaaga
    19741 aatgagaaaa tcaggttaca accttggtgg tgaacagtct ggtcacgtta tcttgatgga
    19801 ttacaatacc acaggtgatg gtcaattatc agcaattcaa ttgactaaaa tcatgaagga
    19861 aactggtaag agcttatcag agttggcggc agaagtaacg atttatccac aaaaattagt
    19921 taatatccga gtggaaaacg tcatgaagga aaaggccatg gaagtgccag ctatcaaggc
    19981 catcatcgag aagatggaag aagaaatggc ggggaacggc cgtatccttg ttcgtccaag
    20041 tggaacagag cccctcttgc gtgttatggc agaagcgcct acaacagaag aagtggacta
    20101 ctatgttgat actatcacag atgtagttcg tgctgaaatt gggattgact aaatcctaga
    20161 aaactagatg aaaataaaaa attatggtac aatagcttat aatattgtag ccgatggaga
    20221 aagacatgaa tcttaaacgt gaacaagaat ttgttagtca gtatcatttt gatgcacgta
    20281 attttgaatg ggaaaatgaa aatggagctc ctgaaaccaa ggtggatgtg aatttccaat
    20341 tgctccaaca tgaccaagaa aatcaagtga cttccttgat tgtcattttg agctttatga
    20401 ttgtatttga taagtttgtc attagtggaa caatctcaca agtaaaccat atcgatggcc
    20461 gtattgtcaa tgaaccaagt gaattgaacc aagaagaggt ggaaaccttg gctcgtccat
    20521 gtttgaacat gctcaatcgt ttgacttacg aagtgactga aattgcatta gacttaccag
    20581 gaattaattt ggagttctaa tatgaaatta gctgttttca cagattcctc tgcttatctc
    20641 agtgaagaga ccttgcaaag agaagacttg tttgtcttgg atattcctgt caatattgat
    20701 ggtgaggaat atgtcgaagg catcaatctg tctgctgagg aattttacca aaaaatggct
    20761 caggcttctg aattgcctaa gaccagtcaa ccaagtattg ccaagttaga tgagatctta
    20821 acttcgctca aagaacaagg ctatacacat gccttggggc ttttcctatc ttctggaatt
    20881 tcaggttttt accaaaatat ccagtatatg gtcgatgact atgagggctt aaccattgct
    20941 ttcccagaca ctttgattac aagtgctccc ctaggcatca tggttgaaag cgtctttaat
    21001 tggcgtgatc agggcgatga ttttgccagc attcaggata agctagccat tcaaatcagc
    21061 cgtacgtcag cctttatcat ggtagatgac ttggatcatt tggtaaaagg tggacgcctt
    21121 tcaaatgggg ctgccatttt gggcaatttg cttagcatta agccaatcct ttattttaac
    21181 gatcaaggtg tgattgaagt ttacgaaaaa gttcgtactg aaaagaaggc caccaagcgc
    21241 ttaattgaaa ttatcaagga aacaacggct tcaggtcaat accgggtcat tgtcattcat
    21301 gggaatgctc ctgaaaaggc tgaagaattg cgtcagcact tgcttgattt tggcttgggt
    21361 tcggatgttt cacttgctac atttggtagt gtcattggaa cgcacctagg agcaggaagt
    21421 attgctctgg gttatattcc agtgatttag ttggcgcttc taggctagtt aagatgcctt
    21481 gtatcttaga aattgaacac ggactacctg cctcttgaaa aaagatgcct gtcttgcctt
    21541 tcgtggaaag tcagtgccat tccctatttt tcagaggcag ctaaggtcct ttgtatcttg
    21601 ataattgaac acgcctggaa ccctgtgtga aaaagatagt tcttccaaga agtagacact
    21661 tcttgattgg aattcctatt ttcactttgt gttcttacgg actttgtatc ttagacagga
    21721 gtagagatga gtattcgagt aattattgcc ggttttaagg gaaagatggg ccaggctgct
    21781 tgtcagatgg tattgactga tccagacttg gacttggtgg cagttttgga tccttttgag
    21841 tctgagtcag aatggcaggg tattcctgtt ttcaaggata aggctgattt agctggtttt
    21901 gaagcggatg tctgggtaga ttttactact ccagctgttg cctacgaaaa tacacgtttt
    21961 gctcttgaaa atggctttgc tccagtagtt ggaacgactg gtttcacgag tgaagaaatt
    22021 gcagagctaa aagaattttc tcgtgcccaa gacttgggtg gcctgattgc ccctaacttt
    22081 gccttgggtg ctgtcttact catgcaattt gcgacgcagg ctgccaaata tttcccaaat
    22141 gtggagatta ttgagctcca tcatgacaag aaaaaggatg ctccgagtgg aacagccatt
    22201 aaaacagctg agttgatggc agaggttcga gagtccattc agcaaggcgc agcagatgag
    22261 gaagagctga ttgctggtgc tcgtggtgct gactttgatg atatgcgcat ccactcagtt
    22321 cgtttgccag gcttggtagc tcatcaggaa gtcatctttg gcaatcaggg agaagggttg
    22381 accctccgtc atgactccta tgatcgcatc tccttcatga caggagtcaa tttgggaatt
    22441 aaagaagttg tcaagcgtca tgagcttgtc tatggattag aacacttatt atgagattaa
    22501 cgcaaatgcc ttctgaattt cagaaggctt taccagtatt agaaaaaatt aaagaagcag
    22561 gctttgaggc ttattttgtt gggggctctg ttcgagatgc ccttctccat agccctatcc
    22621 acgatgtgga tattgcgacg tcttcttatc cagaagagac caagcagatt tttccgcgaa
    22681 cagccgatat cggaatcgag catggaaccg tcttggtctt agatggggat gaggagtatg
    22741 aggtaacaac ctttcggaca gaggatgtct atgtggacta tcgcagaccc agtgcggttt
    22801 cctttgtacg atcgctagaa gaagacctca aacgccgtga tttcacagtc aacgcctttg
    22861 ccttggatga gacaggagaa atcgttgact tgttccatgg tttagaagat ttggaaaagc
    22921 aagtcttgcg agcagttgga gtggctagtg agcgtttcaa cgaagatgct ttacggatta
    22981 tgcgtggttt ccgttttcag gctagtcttg gttttgcact tgagccagaa acatttaaag
    23041 ctatgaagac cttgacgccg cttttggaga aaatttctgt agagcgtacc ttcgtcgagt
    23101 ttgataaact cttgctggct ccattttgga gaaggggctt ggcttccatg attgagagtc
    23161 aagcttatga ctatctccct gatatggcat ctagccagga caagctcaac agactgtttg
    23221 atttggagac tgattttact tttgaatcct ctgaacaagc ctgggcggct ttactatggg
    23281 ctttggagat tgaaaatgcg cagtcatttt tgaaatcttg gaagacctca cgccagtttg
    23341 ccaagcaagt tcaggatttg ctgattattt tggctctgcg tgaaaatgga gaattgagta
    23401 agcgagattg ttatcgcttt gacatagatt tgcttttaca ggctgaaaat cttcgtcaag
    23461 ctcaaggaaa agaagtcaac ccacaagcca tcacagaaaa ataccaaagc ttgactatcc
    23521 atgacaagaa agagattcag attaatggcg atattttgat caaggaatat ggctatcagc
    23581 caggcccaga cttgggagag attttaacag agattgagtt tgccattgtc gatggagaat
    23641 tggagaataa tcgtgaagcc atccatgctt acctgaggga gaaaaaatga gtgattttat
    23701 cgttgaaaaa ctaagtaaat ccgttggtga caagaccgtt tttagggata tttcctttat
    23761 tatccatgac ttagacagaa ttggtttaat cggtgtcaat gggactggca agaccaccct
    23821 tttggacgtc ctttctggtg tttctggatt tgatggggat gtcagtcctt tttcagctaa
    23881 aaatgattac cagattggtt acttgactca ggatcctgat tttgatgata gaaagacagt
    23941 tttggatacg gttctatcta gtgaactcaa ggaaatccag ctcattcgtg agtatgaatt
    24001 gattatgctc gactatagtg aggacaagca ggcgcgtttg gaacgtgtca tggcagagat
    24061 ggactctctc caagcttggg aaatcgaaag tcaggtcaag accgttctta gcaaattggg
    24121 cattcaagac ttatctactc ctgttgggga attgtcaggt ggtctgagaa gacgggtaca
    24181 gttggcacaa gtcttacttg gcaaccacga cctcttgctt ttggatgagc cgaccaacca
    24241 tctggatatt gcgattattg agtggctgac cctctttttg aaaaattcta agaagaccgt
    24301 cctttttatc actcacgatc gttatttctt agacgctttg tcaacacgga ttttcgagtt
    24361 ggatcgtgca ggcttgaccg agtaccaggg caattaccag gactatgttc gcctaaaggc
    24421 ggaacaggat gagcgcgacg cggctcttct tcacaaaaaa gaacaactct acaaacaaga
    24481 actggcctgg atgcgcagac aaccgcaggc gcgtgcgacc aagcagcagg cccgtatcaa
    24541 tcgattccat gatctgaaaa aggaagtttc aggcagtagt gctgagacag acttgaccat
    24601 gaactttgaa accagtcgga ttgggaagaa agtcatcgag tttcaggctg tttcctttgc
    24661 ctatgaaaac aagcctattt tgcaagattt taatctcttg gtgcaggcca aagaccgtat
    24721 cggaatcgtt ggggacaatg gtgttggaaa atcaaccctg ctcaacttga ttgcaggaag
    24781 tcttgagcca actaaaggac aagttgtgat tggggaaact gttcgcatcg cctatttctc
    24841 tcagcaaatt gagggtttgg atgaaagcaa gagagttatc aattacctgc aggaagtggc
    24901 agaagaggtc aagaccagtg gcggttctac gacttcgatt gcagagttgc tggagcagtt
    24961 ccttttccca cgttcgacgc atggaacctt gattgagaaa ttgtcagggg gtgagaaaaa
    25021 acgtctttat ctcctcaaac tgcttttgga aaaaccaaat gttcttcttt tagacgagcc
    25081 aaccaatgac ctagatattg caactttgac agtcttagag aatttcttgc aaggttttgc
    25141 aggtcccgtt ttaacagtca gtcacgaccg ctatttcttg gataaggtag cgaccaagat
    25201 tctcgctttt gaggatagca agattcgtcc tttctttggt cattacaccg actatcttga
    25261 tgaaaaagct tttgaaacag atatggccaa tcaagtgcaa aaggtcgaaa aggaaaaagt
    25321 ggtcaaggtt cgagaagaca agaaacgtat gacctaccaa gaaaagcagg agtgggcaag
    25381 tattgaaggt gatattgaaa ccttggaaaa acgtatcgct gctattgaag aggaaatgca
    25441 ggctaacggc tctgactttg gtaagctggc tactctccaa aaagaattgg atgagaaaaa
    25501 tgaagcactc cttgaaaaat acgaacgcta tgagtatctc agtgaatttg atagttaaga
    25561 ctattcgaaa atcaaagtgc aaactatgtc ggcttcacat tgccgactca agtacagcct
    25621 gtgaccggct tcctaatttg cactttgatt tttattgagt ataaaagaat agaaaaatcc
    25681 cgtctcatga aaggatttct ctattctttt ttggtttctt gatgaaagat attttgccag
    25741 gtttcgtggc gacgccagat actggtatgg atgataccat ctaactcata gcagatgagt
    25801 ttggtttttt gactgatgga agtaatttga atgtccttga tagcagaatt taactctttt
    25861 ttggtcttat aagcctcttt atccatctgc tctccatctt ggcgaatata gacaaaatca
    25921 tcagtcaaga gttcttctag ttggtttcct tggtcaatca attgttcacg cataagcaat
    25981 tttttataga cattgtctaa aatttcatcc tcagagatag gtgctggttc gatatggaca
    26041 tcggtatcaa agacgccaaa acgctcctcc agcatagact cgacctgatc cgcgatttca
    26101 tggctttcaa aaacagacaa gtcaggattc atctctagtg taatatccag gtagatgttg
    26161 ctaccgtagg tgcgacctct ttgcgatttg accttgctga ttttgggaat ttccatgata
    26221 gccttttggt agtcctcgag caggcggtcg tcaaagccat ctgaaagact aaaggaagac
    26281 tcgatgaaga tatcataggc agtcttcaag ataaagaaag tgatgatgat agcaaccagt
    26341 ttatccacaa tcggataatt gaaactacta gctaggatgg caatggcggt tccaagtgag
    26401 gtaacagcgt cagaaagatt gtccttagca gctgccttca gcgccttgga gttggatttc
    26461 ttactgaggc gagtattgta gagatagacc acaaacataa tcgctgcaga aatgattcct
    26521 agagttgcac caagaggatc aatgaccgtt tcttcccgac tgagaatctt ttgaatggta
    26581 tctcttagaa catcgaaacc gacatagaac atgatgatag aagtgatcaa gcttgccaaa
    26641 tcttcaatct tccaatgacc aaaacggtgg tcacggtctg caggctggcg cgccatccga
    26701 atcccgatta agagggccac atttccaatg atgtccgata cgttattaaa accatcggcc
    26761 accaaactgg atgaatgaag gagatgacca gctgctaatt tggctgcaga caagatcaaa
    26821 taggtcgaaa tactgataat ggctccacgc tcagctaact tgagatttga gatagattgc
    26881 ttcattcaac ttcctttcta gtcacatagc attctaccat tatactggtt ttcaaggaaa
    26941 aattcaaata aggcagtttt tactctttga aaactcccca aaatttggta taatggtact
    27001 actcaaggga gtagctggca gaaacctgtg atagtgtcgt cattccgaat tttatgctga
    27061 aaagtatgct ttccggccct atcttaaaca gcgagacttg ttatgattaa caggtctctt
    27121 tttgtttgtc gtgaaaagat atgacagaaa gagagtctgt tttgcacaca atgtcaagga
    27181 ggagacacat gtcaaaagaa caaaaacgcc aagcgtttta tactcagagc cctgaagagg
    27241 tcttgcaggc tgtggatgcg accgagcaag gtttgtcatc aagtgaggcg gaaaagcgcc
    27301 ttgctgaatt tgggcacaat gaactcgaag aaggcgagaa acgatcaatc ttggtcaaat
    27361 tcatcgagca atttaaggat ttgatgatta tcatcctagt tgcggcagca atcttgtcag
    27421 tcgtgacttc tggtggggaa gatatcgcag atgccattat catcctagct gtggttatca
    27481 tcaacgctgc ctttggtgtt taccaagaag gaaaagctga agaagctatt gaagccctca
    27541 aatccatgtc tagtccagtt gcccgcgttc ttcgtgatgg acacatggca gagattgact
    27601 ctaaagaatt ggtaccaggc gatatcgttg cccttgaagc aggtgacgtg gtaccagcgg
    27661 acctacgttt gatagaagcc aactctctta aaattgaaga agcagccttg acaggtgaat
    27721 ctgtaccagt cgaaaaagac ttgtcagtcg agcttgcgac agatgctggt attggtgacc
    27781 gtgtcaacat ggccttccaa aactcaaacg taacctatgg tcgtgggatg ggtgttgttg
    27841 tcaatacagg tatgtacact gaagttggtc atattgctgg tatgcttcaa gatgcggatg
    27901 agactgatac accactcaaa caaaatttga acaacctttc taaggtcttg acctatgcta
    27961 tcttggtcat tgcccttgtt acttttgtag tgggtgtctt cattcaaggg aaaaatccac
    28021 ttggtgagtt gttgacttct gttgcccttg ccgttgcagc cattccagaa ggacttcctg
    28081 ctatcgttac catcgttctt tctcttggta ctcaagtttt ggccaaacga cattccatcg
    28141 ttcgtaagtt gccagcagtt gaaacacttg gttcaactga aatcatcgct tctgataaga
    28201 ctggtacgct gactatgaac aagatgacag tcgaaaaagt cttctacgat gcggttctac
    28261 atgactcagc tgatgatatt gaactaggtc ttgaaatgcc actacttcgt tcagttgtct
    28321 tggccaatga tacgaaaatc gatgtggaag gtaacttgat tggtgaccca accgaaacag
    28381 cctttatcca atatgccttg gacaagggct atgatgtcaa aggtttctta gagaaatatc
    28441 ctcgtgtagc tgaattgcca tttgactctg accgtaagct catgtcaaca gttcacccat
    28501 tgccagatgg tcgtttcctt gtagcagtca agggtgcgcc agaccaactc ttaaaacgtt
    28561 gtcttcttcg tgataaggct ggggatattg ctccgattga tgagaaggtt acaaatctca
    28621 ttcatacaaa caattctgaa atggctcatc aagccttgcg tgtccttgca ggtgcttata
    28681 agattatcga tagtattcca gaaaatctca cttctgaaga gcttgaaaat gatttaattt
    28741 ttactggttt gattgggatg attgaccctg aacgtcctga agccgctgag gctgttcgtg
    28801 tggctaagga agcgggaatc cgtccaatta tgattacagg tgaccaccaa gacacagcgg
    28861 aagccattgc caaacgtttg ggaatcattg acgcaaacga tacagaaggt cacgttttaa
    28921 ctggtgctga actcaatgaa ctgtcagatg aagaatttga aaaagtcgtt ggtcaatact
    28981 ctgtttatgc ccgtgtgtct ccagaacaca aggttcgtat cgtcaaggct tggcaaaaac
    29041 aaggtaaagt cgttgccatg acaggtgacg gtgtcaatga cgcgccagct ctgaaaacag
    29101 ccgatatcgg tatcggtatg ggaatcactg gtacagaggt ttctaagggg gcttctgata
    29161 tgattcttgc agatgataac tttgcgacta ttatcgtcgc agtggaagaa ggacgtaagg
    29221 tcttctcaaa cattcaaaag actattcagt acctactttc tgctaatact gctgaagtat
    29281 taaccatctt cctatcaacc ttgtttggtt gggatgtctt acagccggtt catcttttgt
    29341 ggattaactt ggtaacggat accttcccag ctatcgctct tggtgttgaa cctgcggaac
    29401 ctggtgtcat gaatcataaa ccacgtggac gcaaggcaag cttcttctca ggtggtgttt
    29461 tgagttctat catttatcaa ggtgtactcc aagcagctct tgttatgagt gtttatggcc
    29521 ttgcgattgc ttacccagtt catgtgggtg acaatcatgc tattcatgca gatgccctaa
    29581 cgatggcctt tgcaaccctt ggtttgattc agctcttcca tgcctacaat gtcaagtctg
    29641 tctaccaatc catcttgaca gttggcccat tcaagtctaa gacctttaac tggtccatct
    29701 tggtatcctt tatccttctc atggcaacaa tcgttgtaga accgcttgaa ggaatcttcc
    29761 acgtaaccaa actagacttg tcacaatggg gaattgttat ggctggaagc ttctcaatga
    29821 ttatcatcgt cgaaatcgtt aagtttattc aacgcaaact cggttttgac aagaatgcga
    29881 tttaagggag gtttcggatg tcagcatatc aattaccgac cgtatggcag gatgaagcta
    29941 gtaatcaagg agcttttacg gggctaaaca gaccaacagc aggtgcccgt ttcgaacaaa
    30001 acttgccaaa aggagaacaa gcttttcagc tttattcact gggaacacca aatggtgtga
    30061 aggttactat cttattggaa gaattactag aagctggttt taaggaagcg gcttacgact
    30121 tgtataagat tgctatcatg gatggggatc aattcggctc agactttgtg aagctcaatc
    30181 caaattccaa gattccagcc ttattggacc agtcaggtac tgaaaacgta agagtctttg
    30241 agtctgctca tattcttctt taccttgctg agaaatttgg agccttttta ccaagtaatc
    30301 ctgtggaaaa ggtagaagtt ttgaattggc tattctggca agcaggtgca gcaccttttc
    30361 taggtggggg atttggacat ttcttcaatt atgctcctga aaaattggaa tatcctatta
    30421 accgttttac gatggaagtg aaacgccagt tggatttatt ggataaggaa ttggctcaga
    30481 aaccttatat tgcaggcaat gactatacga ttgcagatat tgctatctgg tcttggtatg
    30541 gacagttagt tcaaggaaat ctttaccaag gttctgcaaa attcttggat gcctcaagtt
    30601 atcaaaatct agtaaaatgg gcagaaaaaa ttgccaatcg tccagctgtt aagcgtggct
    30661 tggaagtaac ttatacagaa attaaatagc aaaaaagtca tcttcggatg gctttttgct
    30721 acagttgagg gaaagggttt gcagttatcg gcttttgtgc tataattgct ataatatagt
    30781 aaaaagcaag aggagtgtga ggaagtggaa aagaaaattg tgaaggatat cttattttta
    30841 tctcaagtgt ctcatccggc aagtcaggag gacctttatc ttgccagaga tttgcaggat
    30901 acactcttag caaatcgtga tacctgtgtt ggtctagctg ccaatatgat tgggatgcag
    30961 aagcgcgtga ttatctttaa tcttggcttg gttcccgtgg tcatgtttaa cccagtgctt
    31021 ctgtcctttg aaggatccta tgaggcagaa gaaggctgtt tgtccttggt aggtgtgaga
    31081 tcaactaagc gttatgaaac cataaggctt gcctatcgtg acagcaagtg gcaggaacag
    31141 accattacct tgacaggctt cccagctcag atttgccagc atgagctgga tcacttggaa
    31201 ggacgaatca tttaggagga aagcaaatga aacgaatagt ctttgaactt atttttatcg
    31261 caacgacctg gtatatcttt ttaccgcccc ttaacctgac cagctgggaa tttctcttct
    31321 tcctctgtgg gcatttgtta gttgtggcaa tcttatttgg ctttggcaag gggataaacc
    31381 ttgtcaaaac ggttcatgtg cgccacggta aggcggaagc tgccttaaat cttgagggtt
    31441 tcaaaatcaa tcggttaggg aaaattctgt tagcttcgat tggaggaatt cttctcttgg
    31501 cagctttggt ttccttggta acttctagca tgtttcaggc taaaaattat gccaatgtag
    31561 tcacggttac ggaaaaagac tttactgaat ttcctaagag tgacaccagt aaggttccta
    31621 tcctagatag aagtactgct gaaaaaattg gagaccgcta cttgggttcc ctaaccgata
    31681 aggtgtcgca atacgtagcg gcagatacct atacccaatt gacaattgat gggaaacctt
    31741 atcgggtcac accactagaa tatgcagacc ctatcaaatg gtttaacaat caagccaagg
    31801 gaatcggtga gtatatcaag gtggacatgg taactggaaa tgcggatttg gtggacttga
    31861 agacaccaat caagtattca gactcggagt attttaaccg tgatgtcaaa cgtcacctgc
    31921 gcttgaagta cccgaccaaa atctttaaaa ctccatcttt tgaggtggac gatgagggca
    31981 atcctttcta tgtagcaacg gtttaccaaa agcaatttgg acttgctgtt cctcgtcctg
    32041 cttcagtcat tatcttggat gctacaaatg gagaaaccaa ggaatacagc ttatcagatg
    32101 ttccagaatg ggtggacagg atctatccag cagaggaaac cattgagcaa atcaactaca
    32161 acggcaagta caaggacggt ttcttgaatg ccatgatttc caagaaaaac gtgacccaga
    32221 cgaccaatgg ctataattac ttgtctatcg gtaatgacat ctatctctac acaggtgtga
    32281 cgtcggctaa tgcggatgag agtaatcttg gtttcatcct tgaaaatatg cgaacaggag
    32341 aaattactaa gtatagcttg gcttctgcga cagaagaatc agcccgtgaa tcagcagaag
    32401 gtgctgttca ggagaaatcc tacaaagcaa ccttcccaat cctcatcaac ctcaatgaca
    32461 agcctctcta catcatgggc ttaaaggaca atgctggctt ggtcaaagag tacgccctgg
    32521 tagacgcagt cgagtaccaa aatgttatcg ttgctactac agtggaagag atgctcagca
    32581 agtatgccaa taaaaacgac cttgaaattg acaatgcaac gacagaaagc atcaagggag
    32641 tagtagcaga cctcaaatca gctgttatca agggagacac tgtctacttc tttaaagttg
    32701 atggcaagat atacaaggta aaggcttcag tatccgatga ccttccttac cttgaaaatg
    32761 gtaaaacctt cgaaggtcaa gtaggaaaag acaattatct caagaccttt aaagtacaat
    32821 aatactcttc gaaaatctct agctctatct gcaacctcaa aacagtgttt tgagcagcct
    32881 gcggctagtt tcctagtttg ctctttgatt ttcattgagt ataaaaaagg tttatttaat
    32941 aaatatatgt tataataagg taaattaagc ctaatggagg acaaagaaat gggtttttat
    33001 ttgatggttg cttcaatgct actcggactg ctcgctttga agataggttt ttctcagttc
    33061 aaggagaaaa aagataaatt cttatctatc ttaacaagtt tagctggcac agcccttgtt
    33121 ctcgtggctg tctggttagg atggcccaaa taaatagaaa aacctcggtc aaaccgaggt
    33181 ttttcaaatg aatttcttgg ttgtggctaa aaaatatgct acactatcaa tatgaaaatt
    33241 ttaatcccaa cagcaaaaga aatgaacaca gacttgccaa gtatcgaggc aattccttta
    33301 aaaccagaaa gtcagaccgt gcttgatgcc ttggctctct attctgccag tcaattggag
    33361 agtttctaca aggtatcagc tgagaaagcg gcggaagaat ttcaaaatat ccaagctttg
    33421 aaaaggcaaa ctgctcaaca ctatccagcc ttgaaacttt ttgatgggct tatgtaccgc
    33481 aacattaaga gagataagct gaccgaggcg gaacaagatt atcttgaaaa tcatgtcttc
    33541 attacctcgg ctttgtacgg tgttgttcca gccttgtcac ccatggctcc tcaccgtttg
    33601 gattttttga tgaaattaaa agtcgctggt aagactttga agagccattg gaaggcagtc
    33661 tatgatgaag ctctgaagaa ggaagaagtg attttctctc tcttgtcatc agagtttgag
    33721 actgtatttt ctaaggaaat cagagcaaag atggtgacct tcaaattcat ggaggataga
    33781 ggcggtcagc tgaagattca ctcaactatc tccaagaaag cgcgcggggc ctttctaaca
    33841 gctttaatag aaaatcaagt acaaactgtg ggggaagcac gtcgcttgaa ctttgctgga
    33901 tttgtttacc gagaagattt gtcacaacca cagggattgg tttttgtaaa ggaagtatag
    33961 aaatcagata agagaaaagt cagcacgatt atgctgactt ttttgataac ttataaagta
    34021 ttggacaaat gaatctcatt tgataaggtg ttaagatgat taaccaaatt catgattgac
    34081 agatgatttc ggcaaataaa cttcttggta atccctgaaa tatagaaatt agacacgatg
    34141 atatcgtaat ctgtctgatt taaaatctca ggacttgttt ttaattcatc ccaaatatcg
    34201 aaggtaaagc ggttattaca gtaataggaa agcatatcaa caaaggtaag ggatatagca
    34261 tggtcaaagt tactgataat caaaaccttg ataggtggtc gattttctaa caactgagta
    34321 gagaggtttt cagcatgggt taagatggtg tacatcaagt gttccaactg ttcaggatgg
    34381 tcatgctgtc caattgcctg acggtattga gccagttctt gacgcgcact tcccataaag
    34441 tctgggaagt aaccttcaaa ttttttaatc gtcaatgctt tttgttcaaa taagattggg
    34501 gtagaaaaga tttcctgtct ttcaaagaaa gcagtgttgt gtaaatgcca aatcagctca
    34561 tcgtggttag taaaagtaat cttatattgt tttgataggc gttctaatat ttgactaagt
    34621 aattggtaag agtatcttgc ttgactgtta tcttctaaag agttgaagaa ttcttgagga
    34681 tctaggaaaa tatcattctg aagaaaagaa ataaaaattt gagcgattgt atctggagtc
    34741 atttcaagcc caaaatgttt agagaaataa gcaagtgtct cctggaaatt tggaatgctc
    34801 tttaaaagag gataatattc tttgtaaaag tggttgggga ggtcaatgaa gtgaccattt
    34861 ttaaccctgt ggatactgat agctatcatc agtttgtaca ttctataaat tgaaaatcgc
    34921 attggataat tcgtgatttt atagaagaag tcagcaaact ctgttaaatc ttcctcagga
    34981 aggtcaggaa aaggccaatc taggaaataa tagcgctcag aaaagtattg ggcaaaaaag
    35041 taacgaatat cgatctcatt tccacgtatc tcggatggag taaaagataa ttcaatttga
    35101 aactgagatg aaagaacctt tgtaatattt ctgcccagtc gatagaggtt ggcactacta
    35161 aagtaaagat tttctattgt tcgataaata ggtagcccct cattgaagaa catatactct
    35221 agtaattgaa aagattgaga attagcaaga aaatattgat aaatatcttc tacactagtg
    35281 ttaacttcta aatctatcat gattccgtta acagaagatt ggatgttaat agatggaaag
    35341 gcaatacgta attcatttaa atcacttttt aagattcgtt ctgtacatcc taatttttcg
    35401 gctagttcat gtaatttcat ccaattacga ttctgaatta gggtttccat taagcgtaat
    35461 tgtctttgaa cttttgtgga taaaaggttt ctcatacggg tatttcctcc ataattcatt
    35521 atatcttttt ttgtctaagt agtataaaaa aattagagca agaaaattgt cgttagtaat
    35581 cggaaaaatt agaataatat aagtggcttt taagtgcaaa aacagaatat attaattgtt
    35641 cagaaaatat tgattaatgc ctcaaatagt tgtacattgt aaactataaa atactatcta
    35701 ggagtttaaa atgaaacatt cacataaaaa atcatttgac tggtatagca tgcaacaacg
    35761 ttattctatt cgtaagtatt actttggtgc agttagtgtc ttgctcggta ccgctttggt
    35821 attaggtgca gcagctagtg tccaaacagt acaagcggaa gaaaacaaac aagaaactac
    35881 caatagtatt tctgttggta ggggagaagc agctactaaa ccagcagagg tttctgcgtc
    35941 taataaagag aaaacctatg cagctccaac tgtagctaat ccagtagaaa cgactccagt
    36001 taaaactgga gaagttacta aaccagcaga aaaagttgaa gaagcaaaag acaaaaaaga
    36061 ggaagtaacg catcaagatg ctattgacaa gtcaaaattg ttaacggctc tttcgcgtgc
    36121 taaaaagtta gaaagcaagt tatatacaga agcaagtgct gctaacttgc aaacaagtat
    36181 ccaagctggt caaagcttgc ttgggaaagc agatgcatct gaagctgaat tatcagcagc
    36241 agagtcatct attcaatcat ctattattgg tctagaactt cgttctaact ctaacaaagg
    36301 aactgtatca gaaactcctg tagcgaagaa agctaatata gttgaagcga aggaagagac
    36361 taatccagct gcaacaactg atcgttcagc tgttgatagt gctgttttgc caactagcac
    36421 agctgccaaa gtagaaacaa cttcagctcc agcatctatt aatgaaatct tgaaaccagg
    36481 tttgagcctt tctgatgctc gccaaaatcc agctatccgt aaggaagatg ttgatagagg
    36541 gtatagtggt tttagagcgg cgcctgctcc aacgaaccaa ccagtaacta atctaggaaa
    36601 taatactgtt ttcactgata ttagcagagg ttctcatact ttccgtggta atggaaattc
    36661 acgtcgtgga aacccgattc attttgatgt aacaacaact agagttagaa atagagtaga
    36721 tttctcaatc agatattcag gaccaggtga gtttgttaat aacaacttta tcttagacaa
    36781 aggaaatgga ttcggagaac cttctcgtgc aactgtttca acaccaaaat taagagacca
    36841 agttaaaaac attagtaagg gtggaaactt tgtttctcat tcaggctaca gtttagaagc
    36901 tgcagtagaa acaagcacca atcaaacaat taagtttagt ttacctatag ccaaccctaa
    36961 tggtgatctg tctgttcgat taagacctgt tacttttaat gtaggtcaag gggaatcagg
    37021 atctgcaact agtaatgatc catatagtaa ctctaactat tacttcagag aaaaaccact
    37081 cctcttggat gcaaatccaa atggtggtac taataataag actgtttcag aagacattga
    37141 cttccaaact gtctatcttc caactagtaa gttaccagaa ggtcaaacta gattagttcg
    37201 agaaggtgaa aaaggacaac gtcaaatcat ctataaagtt catcaattgg gtaacgaaac
    37261 aatcctagga ttgccaatta gtaattcagt tattaaagaa gttaagccac gtattatgca
    37321 aattggtgtg gctaaagatc taatcgatac agtaaaacca cgtgttgatc aaaataaagt
    37381 cggtgataca aataacctca ctttctatct tgataacgat ggaaacggtg tttatactga
    37441 gggcgtagac gaacttgttc aaaaaattgc tattaaagat ggtgctaaag gtgaaaaagg
    37501 agaccgaggc gaacgcggtc taactggagc tcaaggagct aaaggtgaaa aaggagaccg
    37561 aggtgaacgc ggtctaactg gagctcaagg agctaaaggt gaaaaaggag accgaggtga
    37621 acgcggtcta accggagctc aaggagctaa aggtgaaaaa ggagacc
//
LOCUS       DAVBCA010000016        37450 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.016, whole genome shotgun sequence.
ACCESSION   DAVBCA010000016 DAVBCA010000000
VERSION     DAVBCA010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37450)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37450)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37450
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.016"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..775)
                     /locus_tag="VQU19_000737"
     CDS             complement(<1..775)
                     /locus_tag="VQU19_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2480014.1"
                     /translation="MSKETVVYTKRREKIKDNILGYSFLAPALILLGIFLVIPVGMVI
                     YYAFTDYYLLTPDERKFVGLENFIRLTKDPIFLKSFLNTLKFVVWIIPVQLGAALGMA
                     LIVNKKRKGNMFFKVAFFAPVVMSLVVISILWLYLLNPNSGLLNAILNKVGIASQPFL
                     TSPKQAMYAIVFVSAWQGAGYQMLLFLGGMQNIPQDVYEAAELDGFSKWAQFRYITMP
                     LLKPTALFVLLTTLISAFKLIVQPMVMTQGGPLNSTITMV"
     gene            complement(871..2181)
                     /locus_tag="VQU19_000738"
     CDS             complement(871..2181)
                     /locus_tag="VQU19_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HET2480015.1"
                     /translation="MRKGTMLSVVAGLSLAILAGCSGGTNSKQASSSNDIKVWVQFSD
                     ETNEGKAWQKVVDNFNQSGKSKYKVVTEYIPRSGSGGGYEDKVNAAITTNSLPDVITL
                     DGPNTAAYAKSKVITPLDDYLKDNNMDDVLDSIKQQGTYNGKFYAFGFSESNVGVYYN
                     KKMFKEAGIAESELPTLEKPWTWDEFNTIAKKLKDHYNKPAIDFRINSNDEMLPYAYM
                     PLIWSNNGSVVNEDGTKAEGYFNSKESVEAVQFIQNLVKEGYTTVSPVEKGFETGEYP
                     MLLSGSWTIADMNTNYKDIDFGILPYPVSSKTKKLVSPSGSWQLAVTTKSDKKEAASE
                     FVKFATNTESSEIISLGNSVLPIRKSTIENIKDKVSEPMRFLMEQNSKTAHARPVVVA
                     YPQVSRAFQQAMQDISYYEENPNVQKVLDTRTKEMQTAIDQSLK"
     gene            complement(2308..3303)
                     /locus_tag="VQU19_000739"
     CDS             complement(2308..3303)
                     /locus_tag="VQU19_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET2480016.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLRKVQR
                     AIKTLDYIPDNYARGMKKNRTETIALIIPSIWHPFFSEFAYHVEKELLKYNYKLFICN
                     ADSDSQNEIEYIEMLKQNKVDGIIGITYSDIDKYILSDLPFVSIDRHFSENVCYVTSA
                     NYKGGQTAAEELVRRDNKHLAFIGSINMYENETILRSKGFREKAKELGVDVYNFEMKE
                     PLINPEDQIRIFLQSHKEIDGIFTINDMMALRVISVMKELGKIAPDDYQIIGFDGLKT
                     SVDQSYLVSTIVQDIGMMAKESVAMILKMIKREEILEKRIVIPTYFGGDKTTKKI"
     gene            complement(3665..5146)
                     /locus_tag="VQU19_000740"
     CDS             complement(3665..5146)
                     /locus_tag="VQU19_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET2480017.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSS
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            5589..5753
                     /locus_tag="VQU19_000741"
     CDS             5589..5753
                     /locus_tag="VQU19_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HET2480018.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            5837..6403
                     /gene="amaP"
                     /locus_tag="VQU19_000742"
     CDS             5837..6403
                     /gene="amaP"
                     /locus_tag="VQU19_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HET2480019.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            6415..6585
                     /locus_tag="VQU19_000743"
     CDS             6415..6585
                     /locus_tag="VQU19_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HET2480020.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            6624..7232
                     /locus_tag="VQU19_000744"
     CDS             6624..7232
                     /locus_tag="VQU19_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET2480021.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            7263..7466
                     /locus_tag="VQU19_000745"
     CDS             7263..7466
                     /locus_tag="VQU19_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HET2480022.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(7576..7854)
                     /locus_tag="VQU19_000746"
                     /pseudo
     CDS             complement(7576..7854)
                     /locus_tag="VQU19_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895264.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            8052..8339
                     /locus_tag="VQU19_000747"
     CDS             8052..8339
                     /locus_tag="VQU19_000747"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HET2480023.1"
                     /translation="MIVSLKTKSRKAKDMAESIQGWLAQFLVNLFKSITFDCGKEFSK
                     WKDISNHHDSESFFANLGCSRQRRLNEHSNRLLRCHDLPKQTDFNEVSQEF"
     gene            complement(8617..9387)
                     /locus_tag="VQU19_000748"
     CDS             complement(8617..9387)
                     /locus_tag="VQU19_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HET2480024.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTIKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL"
     gene            complement(9402..10250)
                     /locus_tag="VQU19_000749"
     CDS             complement(9402..10250)
                     /locus_tag="VQU19_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
                     /protein_id="HET2480025.1"
                     /translation="MKMKKIKGGTFMMGTNSEEGFLDDFEGPQVAVSVKDFSIADTPV
                     TNQEFAQFVKETGYKTLAERQEWSFVFILFVPEAEREGYPHPAGAPWWLQVPNACWKH
                     PYGENSNLVGLEDHPVVHVALEDALAFCNWSGMSLPTEAQWEYAARGGRQSEYPWGDT
                     LLEGGYYHANTWQGRFPYENTALDRFIGTAPVYEFLPNDFGLYQMIGNVWEWCRNPRY
                     TLLASFNEDDYELPKYGIQDEEYAIRGGSFLCHCSYCNRYRVAARNGCISTSTSSHLG
                     FRCLKE"
     gene            complement(10247..11722)
                     /locus_tag="VQU19_000750"
     CDS             complement(10247..11722)
                     /locus_tag="VQU19_000750"
                     /EC_number="3.1.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HET2480026.1"
                     /translation="MVQTKQPNIILIVVDQMRADALSLNSKDKLVSTPTLDMMASVGY
                     NFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTEC
                     IGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKAYGSQFDYVSDYLAFLKGKVGYDVD
                     LIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPL
                     NPPKYYFDMYMERLPQFLDLHIGNWEVLEKQIPSIYALRGKLKEDDQRRMVAAYFGLI
                     THIDHQISRFLTSLKEFRHDKDTIIWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIY
                     DPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEF
                     HGEHALGKDSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQM
                     KKKLVDFLRYREEGFVVDEELVPVELSKITPTLTKTGDSQS"
     gene            complement(12045..13400)
                     /locus_tag="VQU19_000751"
     CDS             complement(12045..13400)
                     /locus_tag="VQU19_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET2480027.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLDQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGYFTAMMIGFLASIIFCKVMKKNWVIKLPDSVPPAIAKPFTSIIPG
                     FMAMYIVAILTYVFHLLSNDLLIDWVYKVLQTPLLGLSQSFFAVILMIFLNKLFWFFG
                     LHGGNVLAPIMEGLFGVAMLANLDAFQKGEPIPYIWTSGSFGAFVWFGGLGLVLAILI
                     FSRNSHYRKVAKLGLAPVLFNIGEPVNYGLPVVLNPLLFIPFVLSPVFMATVAYWATS
                     WGLVSPVTQNVTWVMPPILYGFFSTAFDWRAIILSVVCLIISVLTYFPFVKMADKTEL
                     S"
     gene            complement(13410..13727)
                     /locus_tag="VQU19_000752"
     CDS             complement(13410..13727)
                     /locus_tag="VQU19_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET2480028.1"
                     /translation="MDESNLESVMGLIMYGGEAKSNAMEAIQAAKKGDFSKANRRLAD
                     ANAALLQAHKAQTEMLTREAQGEETSISLLMVHAQDHLMTSLTFVDLAKEVVEVYERF
                     EKN"
     gene            complement(13744..14061)
                     /locus_tag="VQU19_000753"
     CDS             complement(13744..14061)
                     /locus_tag="VQU19_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET2480029.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            complement(14074..15759)
                     /locus_tag="VQU19_000754"
     CDS             complement(14074..15759)
                     /locus_tag="VQU19_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000791288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 16 glycosylhydrolase"
                     /protein_id="HET2480030.1"
                     /translation="MKNKKLISSLFILFLLIFIHVKVFANENLIKNSNFEQGELFWNS
                     RNRGIINSNESYSNGHYSGMIPSTAINDNRADGYIGQVIDIEPNEDYLVSAFAKVDIS
                     GAEGYFTARWFDNNKQGEIVQNNIGEAVDQTVNTTEWKKYMFSFNSGKHDKVLIQLVK
                     WSEDDTTKKSNIFIDNVEMYQLSKGNSYKKIWRDDFDGEQLNKKYWGYELGSIRGWEQ
                     QHYVRSDENVFLRSGNLVLRATNRSKEDQYFNPRNNHRKVVYNSGSVRTHGKVEFLYG
                     KLEMRAKLPKGQGVFPAFWTLGSDFTLDGKINPVQGRGWPSTGEIDIMELVGERNSNG
                     SGNKTVYQTLHYGQSDNDDGKFAGRGTAFKLSSGNFNDSYHTFSIDWYKDYIVWMVDN
                     HIVRKVYYGSDNIAKKIFNRPQYVQLNLAMGGSWPGVVDNNLSGTEFVVDYVSYSRND
                     LQQHQAEEYYSQSPKINGAKDIVINRGDVPDLLKGITTNSGYELDYSIENEPMFNNFG
                     GNTSVDLLIRNKTEKEKISQMPPGVYNLHYTSRPKHLDYESKVDRKTVTLTIK"
     gene            complement(15764..16660)
                     /locus_tag="VQU19_000755"
     CDS             complement(15764..16660)
                     /locus_tag="VQU19_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HET2480031.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLNRIEELGFDFVCLTGNPGTGVSNREIIKAVQTAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            complement(16663..17925)
                     /locus_tag="VQU19_000756"
     CDS             complement(16663..17925)
                     /locus_tag="VQU19_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET2480032.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFITGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQGALGGPLGLLGNNV
                     IGLLILIFLNSSFWFVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPSWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLED"
     gene            18205..19383
                     /locus_tag="VQU19_000757"
     CDS             18205..19383
                     /locus_tag="VQU19_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HET2480033.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLINQTLKQFLNNCSDYEIEAIGIALPGRYLDDYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
     gene            complement(19611..20057)
                     /locus_tag="VQU19_000758"
     CDS             complement(19611..20057)
                     /locus_tag="VQU19_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2480034.1"
                     /translation="MTIRFEEKVSIENAQFVCQWSNSLGKSFQEQWMGPRIPFLLPLQ
                     ALEGVFSIFDEQEFVGLIQKIRLEDSNLHIGRFFINPQKQEQDLGSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRAQNLYQKEGFEIVQMVEAPVRKYSGLKLE"
     gene            20127..20786
                     /locus_tag="VQU19_000759"
     CDS             20127..20786
                     /locus_tag="VQU19_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HET2480035.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTPLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLGLLFLLYSWELLSLGQVVLITAG
                     LTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCVIIFGKLLL
                     V"
     gene            complement(20838..21989)
                     /locus_tag="VQU19_000760"
     CDS             complement(20838..21989)
                     /locus_tag="VQU19_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HET2480036.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNITIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGDRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(22004..22735)
                     /locus_tag="VQU19_000761"
     CDS             complement(22004..22735)
                     /locus_tag="VQU19_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480037.1"
                     /translation="MLNQDLFDSLEAQKIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WTRPNHIDTAFASADLFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFP
                     LVQKNKSGYLFEYAQMNTLYLNQHSSYKNDEDSHSFPIQMELVSDEMIQEIEQATKNS
                     NIEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDI
                     PNFSELSETEDFEIIPRIEKQEGQK"
     gene            22964..23065
                     /locus_tag="VQU19_000762"
                     /pseudo
     CDS             22964..23065
                     /locus_tag="VQU19_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            complement(23037..23813)
                     /locus_tag="VQU19_000763"
     CDS             complement(23037..23813)
                     /locus_tag="VQU19_000763"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HET2480038.1"
                     /translation="MPKTLTKKLNAIKAAGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIKQAVAYQK"
     gene            complement(23806..25029)
                     /gene="trpB"
                     /locus_tag="VQU19_000764"
     CDS             complement(23806..25029)
                     /gene="trpB"
                     /locus_tag="VQU19_000764"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HET2480039.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGQNLPDALVACVGGGSNAIGLFHPFVEDESVAMYGAEAAGFGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            complement(25007..25606)
                     /locus_tag="VQU19_000765"
     CDS             complement(25007..25606)
                     /locus_tag="VQU19_000765"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HET2480040.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVAADLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQSFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKHGISGTK"
     gene            complement(25593..26360)
                     /gene="trpC"
                     /locus_tag="VQU19_000766"
     CDS             complement(25593..26360)
                     /gene="trpC"
                     /locus_tag="VQU19_000766"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HET2480041.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDC
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNTGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            complement(26357..27361)
                     /gene="trpD"
                     /locus_tag="VQU19_000767"
     CDS             complement(26357..27361)
                     /gene="trpD"
                     /locus_tag="VQU19_000767"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HET2480042.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEDYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            complement(27372..27938)
                     /locus_tag="VQU19_000768"
     CDS             complement(27372..27938)
                     /locus_tag="VQU19_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HET2480043.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMICDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            complement(27935..29296)
                     /gene="trpE"
                     /locus_tag="VQU19_000769"
     CDS             complement(27935..29296)
                     /gene="trpE"
                     /locus_tag="VQU19_000769"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HET2480044.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQAIDRDPLDFLYEVTHKSQHHSDLPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEGMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKALATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMEVELFRY
                     VMHLTSVVKGRLLAELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRSVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            complement(29797..29874)
                     /locus_tag="VQU19_000770"
                     /pseudo
     CDS             complement(29797..29874)
                     /locus_tag="VQU19_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(30479..31480)
                     /locus_tag="VQU19_000771"
     CDS             complement(30479..31480)
                     /locus_tag="VQU19_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET2480045.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     gene            complement(31588..31956)
                     /locus_tag="VQU19_000772"
     CDS             complement(31588..31956)
                     /locus_tag="VQU19_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480046.1"
                     /translation="MKDYKINFDLGKIEYFDNNCLIQVYKFISFYDICEMVFAFHLPP
                     DELITNVIFKEKINSMLKCYIDRLLYVFINPTHFTEKVNLQFYGSFFSYEFICREVGN
                     ILKNKGVKCNLNFFEGEEYL"
     gene            complement(32052..32762)
                     /locus_tag="VQU19_000773"
     CDS             complement(32052..32762)
                     /locus_tag="VQU19_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HET2480047.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
     gene            complement(32765..34456)
                     /locus_tag="VQU19_000774"
     CDS             complement(32765..34456)
                     /locus_tag="VQU19_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET2480048.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDPNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            complement(34468..35478)
                     /locus_tag="VQU19_000775"
     CDS             complement(34468..35478)
                     /locus_tag="VQU19_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2480049.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            complement(35581..36648)
                     /locus_tag="VQU19_000776"
     CDS             complement(35581..36648)
                     /locus_tag="VQU19_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET2480050.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVK"
     gene            complement(36673..37332)
                     /locus_tag="VQU19_000777"
     CDS             complement(36673..37332)
                     /locus_tag="VQU19_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HET2480051.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
BASE COUNT        12046 a         7633 c         5729 g        12042 t
ORIGIN      
        1 acaccatagt aattgttgag tttaatgggc caccttgcgt cataaccatt ggttgtacaa
       61 tcagcttaaa agcagaaatt aaagttgtta acaatacaaa cagggctgtt ggttttagta
      121 ggggcatcgt gatataacga aactgagccc attttgagaa tccatctaat tcagcagctt
      181 catagacatc ttgtggaata ttctgcattc ctcctaaaaa taaaagcatc tgataacctg
      241 caccctgcca agcagaaaca aaaacaattg catacatagc ttgtttagga ctagtcaaga
      301 aaggttgaga agcaatacct accttattta aaatagcatt taataagcca ctatttggat
      361 ttaaaagata aagccaaaga atagaaataa ctaccaagga catgacaact ggagcaaaaa
      421 aagccacttt aaaaaacata tttccttttc gctttttatt gacaatcaaa gccattccta
      481 aggccgctcc caattgaact ggaataatcc aaacaacaaa tttcaaagta ttcaagaagc
      541 tctttaagaa aatcggatct tttgttaatc gaataaaatt ttcaagtcca acaaattttc
      601 tttcatctgg tgtcaacaaa taataatctg taaaagcgta ataaatgacc attccaactg
      661 gaattactaa aaagatacct aataaaatta aagctggagc taaaaaacta taacctaata
      721 tgttatcctt tattttttca cgtctttttg tatacacaac agtttcttta ctcatatcca
      781 tctcctttaa tcatatatat caaactaggc tattaacaag aaaggggaag gtagttccaa
      841 acattttcct tccaccttct tttttacaga ttatttgagt gactgatcaa tagcagtttg
      901 catttctttt gtacgagtat ccaagacttt ttgcacattt ggattttctt cataatagct
      961 aatatcttgc attgcttgtt gaaaagctcg agaaacctga ggatatgcta cgacaactgg
     1021 gcgagcatga gctgtttttg aattttgttc catcaagaaa cgcattggtt cggatacttt
     1081 atctttgata ttttcaattg tagatttacg aattggaagg accgaattcc ccaagctaat
     1141 aatttcactt gattctgtat ttgtagcaaa tttaacaaat tcagatgcgg cctctttttt
     1201 atcagatttt gtcgtcacag ctaattgcca actacctgaa ggggatacta attttttcgt
     1261 cttactagat actgggtaag gaaggatacc aaaatcaata tctttgtagt ttgtattcat
     1321 gtcagcaatc gtccaagaac cactcaaaag cattggatac tctcctgttt caaaaccttt
     1381 ttcgactgga ctaacagttg tatagccttc ttttacaaga ttttgaatga attgaactgc
     1441 ttctacactc tctttggagt tgaagtatcc ttctgccttt gttccatctt cgtttacgac
     1501 agaaccatta tttgaccaaa tcaacggcat ataagcatat ggcaacattt catcgtttga
     1561 attaatacga aaatcaattg ctggtttgtt ataatgatct ttcaattttt tagcaatcgt
     1621 attaaattcg tcccatgtcc atggcttttc tagcgttgga agctctgatt ccgcaattcc
     1681 agcctctttg aacatttttt tattgtaata aacaccaaca ttcgattcag aaaatccaaa
     1741 tgcatagaat ttcccattat aagttccctg ttgtttaata ctgtccaaaa catcatccat
     1801 attattatct tttagataat catctagcgg agtaattact ttagattttg cataagctgc
     1861 cgtatttggt ccatcaaggg taataacatc tggaagacta ttagtcgtaa tagcagcatt
     1921 aaccttgtct tcatatcctc caccactacc actacgagga atatactcag ttacaacctt
     1981 gtacttactt tttcctgatt gattaaagtt atcaacaact ttttgccaag cttttccttc
     2041 atttgtttcg tcagagaatt gtacccagac tttaatatca tttgaagaac tcgcttgttt
     2101 tgagttagtt cctccactac aacctgcaag tatagctaac gatagccccg caacaacaga
     2161 taacattgta cctttacgca tcatttttct cctttttgaa acgtttcatt ttttatttat
     2221 tttttaaaca agcttctagc ctatttttga aacgtttcat ttgttgatta tattataaca
     2281 gcgctttcat taattgtcaa gcgcttttta aatttttttt gttgttttat ctcccccaaa
     2341 atatgtggga attacgattc gtttttctag aatctcttct cgcttaatca ttttcagtat
     2401 cattgcaaca gattcttttg ccatcatacc aatatcttga actattgtag acactagata
     2461 agattgatcg acagaagttt ttaaaccatc aaacccaatt atctggtaat catcaggtgc
     2521 tattttcccc agttctttca taacactaat aactctcaga gccatcatat catttattgt
     2581 aaatatacca tcaatttctt tatgagattg caaaaaaatt cttatctgat cttcaggatt
     2641 tattaaaggt tctttcattt caaaattata gacatctact cctaattcct tagctttttc
     2701 tctgaatcct ttacttctga gtatagtctc attctcatac atattaattg aaccaataaa
     2761 agcaaggtgc ttattatccc ttctaaccag ttcctctgct gcagtttgtc ctcctttgta
     2821 atttgctgaa gtaacatagc atacattttc cgaaaaatgt ctatctatac ttacaaacgg
     2881 taaatcagat aaaatatatt tgtcaatatc agaatatgta ataccaataa ttccatccac
     2941 tttattttgt ttcaacattt cgatatattc gatttcattt tgtgaatcgc tatcagcgtt
     3001 acaaataaat aatttataat tatattttaa taactctttc tcaacatgat aggcaaactc
     3061 cgaaaaaaat ggatgccata tgctcggaat aatcaaagcg atagtttctg ttctattctt
     3121 tttcatacct cgagcataat tatcagggat atagtccaat gtttttatag ccctttgaac
     3181 tttccttaaa gttacttctt taatgccttt ttctttatta attacacgtg aaacagttcc
     3241 aacactaact cctgcttcta aagcaacatc tttcatggta attgattttc tttgttctac
     3301 catattatca cctcctttca atatatagta tcatgcaaat gctttttaag caactatttc
     3361 tcaatcattt ttggccagat catttatccc atcatgaata aaatcactcc aattagcttt
     3421 tgaaaatact tcaattttca tgtgtaaaca tctacataaa acaggaaaag ccttggtttt
     3481 atggcttttt tcgtatcttc tacaaaaaaa gcaagagttt tagagggcta taaatctaga
     3541 tgtacatttt gcttaaatga ttgaaggtct tttcttaaca aaaacacccc aaaaattaga
     3601 ttttttctgt ctaacttttg aggtacagtt caaacgcgaa atagcgtttt tttgttattt
     3661 ttggttactc atctaatcga ataaacatca tggcatttaa caaatatatg agtgagaccg
     3721 tgtttatatt atttgaatag atgagtctct tattttcaat aggaggaata ataaaattag
     3781 aaataatgat atcataagat gaatcttcta aagattcctt tgataattct aattcagtcc
     3841 aaacttccag ttcaaaatta ttgctacagt aataagaaag tgtctctgca acgaattttg
     3901 catgatactg atcaaaatta ctcataacca aaacctttag tttaggctga ttttgtagca
     3961 aattaatcac caaatgtttg gtatgagtga tgaaggtata agatagatga tttaccatca
     4021 ttgaactaga acaaacctca agagtctcta aatagtgaga aagctctttt tttatatctg
     4081 aaacaaattt tggaaaaata ttttgaaagt tcctgattgt attccctttt tgatcaaata
     4141 aaataaactc agtaaacaac tcttgacgat acagatgtgc ggtattatgc agatgccaaa
     4201 tcagattatc cttattctcc atttcaatct gatacttgac tgaaatctga tcaataaaat
     4261 cactcaatag atggtaagat ttttcaacat aactatcctt ttttacgcat ttcataaaga
     4321 gactttcatc tatgaaaaac attttttgaa agtaagacac aaataattgg caaacaactt
     4381 cttcatctaa agagatattg tattctgatt caaaactctg agcaacacct tctattcctt
     4441 ctgcctgcat taaaaaatcc aaactttggt cgttaaaaga atctttatct acttccataa
     4501 aatgaccaaa ctttattcta tataggttcg taactaggag caactttagc attctatgcg
     4561 ttgacaaatt cattggaaag cttgtttcct tataaaccaa ttctaacaat tgagatagtg
     4621 gctctgatga aaaattttca aatggccatt ctaggaaata atatttttct gaaaaatatt
     4681 gtgcaaaaaa gtaacgaatg tctctctcat ttccaatgat ttgaacaggg gtcagactga
     4741 cttcaaattg aaattgcctt ttaatcactt tattgatttg gctaataata cgatagagcg
     4801 aagatgaact gatataaaat tctttacaaa tactctcagc ttgacaacct tcattaaaga
     4861 agatgaattc taaaatcgaa aaatgagttg aatgtttaaa gaaatgatgg taaaccattt
     4921 caatatcact atcatcggta ttaataatgc gtataccatt agtagaagaa tgaaaaatca
     4981 agtcaggaaa agcagattta acatgggata gatcatcttt gactgcacgt tctgtacaat
     5041 ttaataactc tgctagttca gaacgatgaa accaacgttt atgttcaaat aataattcta
     5101 ataattctaa ttgcctatga ctttttttag ataataaatc tctcatgaat atctttctct
     5161 ctttataaat tatcggatta aacctcttgc aattatacca caaagaatag gtatagcatg
     5221 atataacgac ttttcctaaa atcttttatt tcgtataata acactacgga gacaatatat
     5281 aaacaatttt cttattttac cgtctattga gggcgtgaat acagaatcaa attcaagtct
     5341 aaagattata tttttaattt taaaaattat ataatagcaa caattaaaga atttgatttt
     5401 ttaaaattat ataataataa caatcgaaat aattgacttt tctatattaa agttatataa
     5461 tagtattaat caaagaaatt gattttttga tattaaaata aaaaaggagg gtaggcagtg
     5521 ttgtgatcaa ttattgctgg aggtcttatt ggtctcttgg caggtaaaat cactaaaaaa
     5581 gtagttctat gggaatcatc gcaaatgtat tcgctggttt agtcggggca tatgcaggac
     5641 aatctctttt aggtagttgg ggtccatcaa tcgctggaat ggctttgctc ccatctattg
     5701 taggtgcagc gattgtgatt actgtagtgt cattctttac aggtagaaag taaacttttc
     5761 gccagtaaag ttagcaaact atttttaaat caatgacggg aaaaatagtt taaatgttaa
     5821 atcgaaagga ttgtatatgt caaaagcaaa gaaaatatgt ttcattattt tctgtatttt
     5881 aatcttgaca attttccttc ctgttttgat agattatcat caagttagtg atctaggtat
     5941 tcatctactt agctggagac agaactccgt agttgaattc tatcttgcta gatatgtctt
     6001 ttgggggaca gtggttctat caactttagt tttattatcc attttagttg tgatgtttta
     6061 tcctaaacgt tacttggaaa tccaacttga aactaaaaac gatacattaa aattaaagaa
     6121 ttcggcaatc gaaggttttg ttagaagttt ggtgagtgat catagattga tcaagaaccc
     6181 aactgttcat gtaaatttac gaaaaaataa atgtttcgtt catgtagaag gtaaaattct
     6241 tccttcagac aacatcgctg acagatgcca aataattcaa aatgaaataa ctaatggatt
     6301 gaagcagttt tttggtattg agcgtcaagt aaaacttgaa gttgcagtaa aaaattacca
     6361 accaaaacct caaaacaaaa agactgttag tcgtgtgaag taaggaagta aaaaatggaa
     6421 tggcttaaac aatatcgata tccaattatc gctggtctca taggcgtatt tctggcttgt
     6481 ttgattgtct cctttggctt cttcaaaaca atatttgtat tgattttagg agcactggga
     6541 gttgcagctg gattatatat cgaaaaaaac tatatagata aataaaaaaa taaaaattac
     6601 taatttaatt aaaggagttt catatgtcaa acgaaaaaaa cacaaatact aacgtagaaa
     6661 agaaagatgc tactgttgta gctcacgaaa tcaaagggga acttacttac gaagataaag
     6721 ttatccaaaa aatcattggt ctttcactag aaaacgtttc aggtcttttg ggaatcgatg
     6781 gtggtttctt ctcaaatctt aaagaaaaaa tcgttaacag cgatgacgta acaagtggtg
     6841 ttaacgtaga agttggtaaa acacaagttg cagttgactt aaacgttatt gttgagtacc
     6901 aaaaaaatgt tccagcttta tattcagaaa tcagagaaat cgtatcttca gaagttgcta
     6961 aaatgactga cttggaaatt gttgaaatca acgtaaacgt tgtcgacatc aaaactaaag
     7021 aacagcatga agcagactca gtaagccttc aagatcgcgt atctgacgtt gctgaatcaa
     7081 caggagaatt cacttcagaa caattcgaaa aagctaaatc tggtcttgga tctggtttct
     7141 caactgttca agaaaaagtt agcgaaggtg tagaagctgt taaaggtgca gcaaatggtg
     7201 tagtatctca cgaaaacact cgtgtaaact aagataaaat aaatataaca ggagaaatta
     7261 tcatgtcagt agaagaaaaa ttaaatcaag ctaaaggttc tattaaagaa ggtgttggga
     7321 aagccatcgg tgatgaaaaa atggaaaaag aaggagcagc tgaaaaagtt gtttctaaag
     7381 taaaagaagt tgccgaagac gctaaagacg ctgtagaagg tgctgtagaa ggtgttaaaa
     7441 acatgttgag tggcgatgat aaataaggtt aaaagttact ttatcttttt ggtaacatta
     7501 gtcaaaagag tctgagtcaa gatgattctc agaaaacaaa aagctagaga ttcccaattg
     7561 cggaactcta gctttttaat tttgcctctt tctcttatta tatttcagca ggttgttggc
     7621 catgagtatg aatcccatgt caattctcac ttgacgctta cctctcagat gacatctctt
     7681 ataacccaaa caaaccttta tctgcccaaa gacagatttc atatcaatct tacgtttagc
     7741 gaaaatttgt ctacccttgg aagataaaag tgcctgatat tctttagttt ttaaacactg
     7801 gtaacgttca ttcatataca gtcccttttg aggggctgat tcaggttcat aatcgcagtc
     7861 aacattgatt tcaaggctgt ttgctttcta tctccccttt ttcatgatat attttcgtac
     7921 aggttcttca atagtttcta tagtaaaatg aaccaaaaat agtacacgtt gcggtataat
     7981 gttcttgtgg catattcatt agattttcgt aaacagttct ctcctatttg tgagcgaaca
     8041 agtatagtca attgattgtc agtttgaaga ccaagagtcg taaggcaaag gatatggcag
     8101 aatccatcca agggtggctg gcacaatttc tagtgaacct ctttaaatct attacgtttg
     8161 actgtggaaa agagttttca aaatggaaag atatttccaa tcatcacgat agtgagagct
     8221 tttttgcgaa tctaggatgt tcaagacagc ggcgtctcaa cgaacattca aatagacttt
     8281 taaggtgtca tgacttgcca aagcagacag atttcaacga agtcagtcaa gaattttagg
     8341 ctggacaaaa actcaatttc aggagaaaat gaaataaata ttcccacaat aaaacgcata
     8401 gtatcaaagt ttttccaaca cctgatatta tgcatttttt aattttaaag actttttccc
     8461 agcctcaaga aatcacatcc cacctaaatc ctttggatac caaatacctc atcaggtatt
     8521 ttctgagttg gtaagaatgt ctagcttaat ttgacaaatg gagggcgtta aatccagttt
     8581 ttacaggaag tctatttaaa tattttcaca ctgaccttac aaaatatgaa ataaattata
     8641 taaagtcatt cccatgacaa agaataacat ccctttaaaa cagtatctta cccaattttc
     8701 aggtaagact tttgatacaa ccgtccccaa tacccctccg catatagaag caagaaaaat
     8761 aactggaaca ggtgctaaat gatactgatt taaacctgta accacaacaa ttgtagccaa
     8821 atgagacagc tgggaaaaga aaataattgc aagagaatac atcgttgctt cttttatcga
     8881 aatagaaaaa aacaccatca ataaagatac attgagcgga ccaccaccaa tccctaaaaa
     8941 actagaaatt aagcccaata gaagaccaca aatcatatag aatcctatct tatcaaattg
     9001 ataagttttt ttaaaatctg ttaaaacaaa tgatacaagt agcatcacaa atagtaaaat
     9061 catttgaaca atggatacta gccgtactga taactgagat aacaaaactt gaaaaataag
     9121 atgacctaga aatcctccta aaacagaaga aaaggatacc gtaaaaatca atctccattt
     9181 tatctcttta ctttgtgaaa atcttttgat tgttgaaata atcgccatta taaaaacaga
     9241 gaaactagaa taaaaagcaa tatcactgac cgaatggtat ccaaaactat ccataagtgg
     9301 cttaattata attccaccac ccatgcctga tatagaaccc aatccactag ctattataat
     9361 gattagaaaa taaataatct caaccacttt ttaagtccat cctattcttt caaacatcta
     9421 aaacctagat ggctactagt ggaagtagag atacatccat ttctagcagc tactcggtat
     9481 cgattacaat aagaacaatg acataaaaag gaacctcctc tgatagcata ctcctcatct
     9541 tgtatcccat attttggcaa ctcatagtca tcttcattaa aactagctaa taaggtatat
     9601 ctcggattgc gacaccattc ccaaacattc ccaatcattt gatatagacc aaaatcatta
     9661 ggtaaaaatt catagacagg agccgttcct ataaatctat ctaaggcagt attttcataa
     9721 ggaaatcttc cttgccaagt attggcatga taatatccac cttctaaaag agtatctccc
     9781 caaggatatt cagattgtct tcctcctcta gcagcatatt cccactgtgc ttcagtaggt
     9841 aaagacattc cgctccaatt acagaaagcc aatgcatctt ctaaagcaac atgaactact
     9901 ggatggtctt ctaaacccac tagattactg ttctcaccgt agggatgttt ccagcaagcg
     9961 ttcggaactt gtaaccacca cggagcccca gcaggatgag gatatccctc cctttctgcc
    10021 tctggaacga acaatataaa aacaaaagac cactcttgtc gctcagctag tgttttatag
    10081 cctgtttctt tcacaaattg agcaaattct tgattcgtaa ctggagtatc cgcaatggaa
    10141 aaatccttta cactaacagc gacttgagga ccttcaaaat catctaaaaa gccctcttca
    10201 gaatttgttc ccatcataaa tgtcccaccc ttgatttttt tcattttcat gattgactat
    10261 cccccgtttt cgttagagtt ggcgttattt tagaaagttc aacaggaact aactcttcat
    10321 ccacaacaaa accttcttct ctatatctaa gaaagtctac taattttttc ttcatctgac
    10381 gaacaatagg ttggtatttt tcgcttggat acaaatcatt catttcatgc ggatcttttt
    10441 tcatatcaaa taactgataa tgatttaaaa caggaaacca gataaatttc cactggtctg
    10501 tcaagatata ttgactagaa tcttttccta aagcatgttc accatgaaat tctgttcgcc
    10561 acccctcgta ctgtccaaat aataaattct taacactccg tccatctagt tcatctgtag
    10621 tagttcctcc tgccaaatcc acgagtgaag gaaaaatatc ttgaattttc actaattgct
    10681 tgattgttcc cctattacca gctatcaatc cagccggatc gtaaataaac gaaggaatgt
    10741 ggatacttcc ctgataagga tatccctttc taaacagata atgttcacca agctgatctc
    10801 catgatccga aacaaaccag ataatcgtat ctttatcatg acgaaattct tttagggaag
    10861 tcaaaaagcg actaatttga tggtctatat gagtaatcaa tccaaaataa gcagcaacca
    10921 ttcttctttg atcatcttcc tttaatttcc ctcttaaagc ataaatagac ggaatttgct
    10981 tttctaatac ttcccaattc ccgatatgca aatcgagaaa ttgaggcaag cgttccatat
    11041 acatatcaaa atagtatttt gggggattta atggagcatg tggtttttca aaagacattt
    11101 tgagaaaaaa aggaaccgtt ggatctcttc tttgtaaaaa tgaaatggac tcactcacaa
    11161 cccagtttgt tggatgtaac ttctcatctt tatcccaagg tctagcttcc caagaattac
    11221 aatccattcc gtcatcaatc aaatcaacat cataaccaac tttacccttt aaaaaggcta
    11281 gatagtcact aacataatca aattgacttc cataagcctt atcatacttt ctatcaacat
    11341 gtagataccc atcgtgaagt aagacatgat caaacccaag tctctgtctg gaaggaaaaa
    11401 catgcatctt accaatacac tctgtttgat aacccatatc tttaaagact tttggaagag
    11461 tattagtaaa attccaaggc acctcatctt gataaccaac acgtccactt ttatcttggt
    11521 ctaagccagt caataaagct gccctagcag gaacgcaaga aggaactgga gaataggcat
    11581 tttcaaaatt ataacctaca ctagccatca tatctaatgt tggagtgcta actagcttat
    11641 ccttactatt caaggataag gcgtctgctc tcatttgatc tacaacaatc aaaataatat
    11701 ttggctgttt tgtctgaacc ataaaatctc ctttctaata tggcaaaaga ggcacaagaa
    11761 gatatctacc tttactgcac ccctttctat atcaatctct ctatataaag caataacatt
    11821 cttgttatgt tttatagaac aatgaactaa aatatgacta aatcgattag gaaattcaaa
    11881 tcattttcta gtactgtttt agaagttaca gtgtactatt ccaacttcaa caaactataa
    11941 accttggtct aataacaatt ttagtggaga taagaaatcc tacacctaac tcatcttaca
    12001 cgtaatctat ttctatttta tcacaaaaaa cgcaagtaag accattaact caattcagtt
    12061 ttatctgcca ttttcacaaa tgggaaataa gtcaagacac taataatcaa acaaacaact
    12121 gataagatga tggcacgcca atcaaatgct gtagagaaga aaccatataa aattggaggc
    12181 attacccaag taacattttg tgtaacaggt gaaacaagac cccagcttgt tgcccagtaa
    12241 gctaccgttg ccatgaaaac cgggctaagt acaaatggta taaatagcaa aggattcaag
    12301 acaactggta aaccataatt gaccggctca ccaatattaa acagaactgg tgctagacca
    12361 agtttagcaa cttttcgata atgactgttt cttgaaaaaa ttaaaatagc aagtaccaat
    12421 cctaatcctc caaaccagac aaacgcccca aaagacccac ttgtccatat ataaggaatc
    12481 ggttcacctt tttggaaagc atccagattc gctaacatag caactccaaa cagcccttcc
    12541 atgatgggag ccaatacatt tcctccatgg agaccaaaaa accagaataa cttatttaaa
    12601 aagatcatca gaataactgc aaagaaactt tgagacaaac ctagtaatgg cgtttgtaac
    12661 accttgtaaa cccaatcaat caataagtca ttgctaagta aatggaaaac ataagtcaag
    12721 atggctacta tatacatcgc cataaatcct ggaatgatag aagtgaacgg cttagcaatc
    12781 gcagggggaa ctgaatctgg taacttgatt acccagttct ttttcattac tttacagaaa
    12841 ataatagagg ctaaaaatcc aatcatcatg gctgtaaagt agcctctggc attaatatgg
    12901 tttcctggaa tcacattccc aatagttacc atcagatttt taccatcaaa tgctagatta
    12961 tcaattcctt gtaagatctg atctaatttc acatctccta catttgccaa agggaaactc
    13021 tttgtaactg tacttccaat cgaaatgaca aacgaagcaa gtgataccaa accagcagaa
    13081 actgtatcaa ccttgtaaat cttagcgata ttcactccca agcaatagat gaacaacaaa
    13141 gaaacaattg gtatacttcc cttgaatacc aaattattga tgtcaacaag ccactgaaag
    13201 gttttcgtaa tactttctag gtgaaattgt tgtggtaaat ccactagaaa agcatttaat
    13261 aacaaagcaa tggaacctgt cataataaca ggcatagtcc ccacaaatga atcacgtaaa
    13321 gcaactaaaa acttctgatt cccaactttc attgcaattg gagaaagttt ttcttgcatt
    13381 ttatccaaca ttgtattcat actaaactcc taattttttt caaatcgttc gtatacttct
    13441 accacttctt tcgccaagtc aacaaaagtc agactcgtca ttaaatgatc ttgcgcgtgt
    13501 accatcaaga ggctaattga tgtttcttcc ccctgtgcct ctcttgtcaa catttctgtt
    13561 tgagccttat gcgcctgtaa taaggcagca ttcgcatcag ctaatcttcg attggcttta
    13621 gagaaatccc ctttttttgc tgcctgaata gcctccatag cattactttt ggcttcccca
    13681 ccatacataa ttagccccat tacagattct aaattacttt catccataac attctcctca
    13741 atcttagtct aataaacttt cagctaaatc taaaacttta gaaccattca tcattccgta
    13801 atctgtcatc ggaataaccg ccacaggaat ctgtctatct tttagttttt cttgaaagtc
    13861 ccctagtaaa tagcgaactt gggggcctaa aagcaacaca tttacttctt ttgttgctac
    13921 aatttcttct gcttcaggag ctggaactgc aaaaatttct gcatccaacc ccttatcttc
    13981 tgctgccttt tgcatctttg tcactagcag acttgtactc atacctgctg cacacgctaa
    14041 cataattgtt actttagcca tagcttactc cttttatttt attgtcaatg ttactgtttt
    14101 tcgatcaact ttagactcat aatctaaatg tttgggacga ctagtataat gcaaattata
    14161 aactcctgga ggcatttgtg aaatcttttc tttttcagtt ttattgcgaa ttaataaatc
    14221 taccgaagta ttccctccaa agttattaaa cataggttca ttttcaatag aataatctaa
    14281 ctcatatcca ctattagttg taattccttt taataaatca ggaacatctc ctctgtttat
    14341 tactatatcc ttagcgccat ttattttggg agattgacta taatactctt cagcttgatg
    14401 ttgttgtaaa tcatttctag agtaagaaac ataatcaact acaaattcag tccctgataa
    14461 attattgtcc actaccccag gccaacttcc tcccatcgct aaatttaact gaacatactg
    14521 aggtctatta aaaatctttt tcgctatatt atctgatcca taatatactt ttctaacaat
    14581 atgattgtca accatccata caatataatc tttataccaa tcaattgaaa aagtatgata
    14641 cgaatcatta aagtttccac tcgataattt aaaggctgta ccacgtcctg caaattttcc
    14701 atcatcatta tccgactgtc cataatgaag cgtttgataa actgtcttat tcccacttcc
    14761 atttgaattt cgttcaccaa ctaattccat tatatctatc tcacctgttg acggccatcc
    14821 tcgtccctga acaggattaa tcttcccatc aagtgtaaaa tccgatccaa gagtccagaa
    14881 agcaggaaaa actccttgac ctttcggtaa ttttgcacgc atctctaatt taccataaag
    14941 aaattctact ttcccatgtg ttctaacact tcctgaatta tatacaacct ttctgtgatt
    15001 gtttcttggg ttaaaatact gatcttcctt agagcgattc gtagctctaa gaactaaatt
    15061 tcccgaacgt agaaaaacat tctcatcact tcttacataa tgttgctgtt cccaaccacg
    15121 aattgatcct aattcatatc cccaatattt tttatttaat tgttcgccat caaaatcatc
    15181 tctccaaatt ttcttatatg aatttccttt agacagttga tacatctcta cattatcaat
    15241 aaaaatatta gatttttttg tagtatcgtc ttctgaccat ttcactaatt gaatcaaaac
    15301 tttatcgtgt ttaccggaat tgaaagaaaa catgtatttt ttccattcgg ttgtattaac
    15361 tgtttgatca acagcttctc caatgttatt ttgaacaatc tctccttgct tattattatc
    15421 aaaccatctt gcggtaaaat atccctctgc tccactaata tctactttgg caaaagcaga
    15481 tactaaataa tcttcattag gttctatatc aataacttgt ccaatatatc catctgctct
    15541 attatcatta attgcagtag aaggaatcat acctgagtaa tgtccgttac tataactctc
    15601 atttgaatta attattcccc tatttctaga gttccaaaac agctctcctt gctcaaaatt
    15661 tgaatttttt attaaatttt cattagcaaa aactttcaca tgaataaata ttaataaaaa
    15721 taatataaat aaacttgaaa ttaatttctt attcttcatt ttatcaccta tttactgacc
    15781 tagccaagcg agatactgta tgtctcactc ctctaattgc cttgctcaat gcataaatat
    15841 tatcgactgt tgccagtccc ccatatcctg cgtcacctat atgttgaata tcaactccac
    15901 aaattttatt tctaagtgca atttccttga tagtatctgt atcagatgtt tcttggctag
    15961 taccaatagc actcagtact agcccaccct tactatgaac gagatcaacg acttcacgca
    16021 actcttggtc atgaaaggct ggaacggttc caactgctgg aacaagtatc acatccgcac
    16081 ctgcttccaa caattgctct gcgacagaaa gctctgccac aggctcattc actcctgccc
    16141 cgtgcatctt acctgcaata atcaaaccag aaaagttttc cttagcagtt tgaacagcct
    16201 taatgatttc tcgattgcta actcctgttc caggatttcc agtcaaacag acaaagtcaa
    16261 aacctaactc ctctattcga ttcaatgttt caacactagc aacacgacct gcaacaattt
    16321 cctgtgtttc ctctagcatc tttgcagatg ggtcaatcgg ttccaaattt acaccaattg
    16381 gacaagcaac aagctggtgt aagcgatgaa taacatcatc acctgaacta tccaaagcat
    16441 aaattttagg ctcaaaaaca tcaacacaat tcaataaaat catatcagct ccaaaagctc
    16501 tagcaatttc agaattagtt atatccccaa caaatgtctc acgagtaact acattttcag
    16561 atagaacaac tctaccttca cttgctaaaa tactttgttt taattcttca gcattcatct
    16621 gtaatatctc agatggattt gcactaatta aacgtttcat tctcaatcct ccaataactt
    16681 aaaccgtttt tcaatagcta ttacaaatgg taaataaagt aagacatcca aaacaatcaa
    16741 tacaatttgt aataatgaac cagaaatact tcctgtagca agtaaaccac ttataacagg
    16801 tggcatagtc caacttggat ctgtataagt tagcggaacc aaacctgatg ccattgctcc
    16861 ccacgctact agtaagttaa acattggagc taagataaat ggaactagta acaaaatgtt
    16921 caaaacaata ggaacgccaa acattgctgg ttcatttata ttaaataatc caggtataac
    16981 agttataggt gccaaagttt ttagttgttt actagctttc ttcttatgtg ctaaatatcc
    17041 taacgcaaga actaaaccta tggttgcacc accgccacct atgaatacaa aattatccat
    17101 aaatacgcta gtaaaaatat ttggaagagt ttctccagtt tgataagcta ctttatttgc
    17161 atctagatta gctaaccata acggtttcat aactgcatta acaacatttc ctccgtgtaa
    17221 tcctacaaac caaaaactac tattaaggaa aattaagata agaagaccaa taacattatt
    17281 tcctaaaagt ccaagtggac ctcccaaagc tccttgagca atttcatgaa gattaggtaa
    17341 acttaattta tctaaagttg cataaacaat caaccaacca acaatagtca ctgcaccagg
    17401 aataatggca ctaaagcttt tagatactgc tggtggaaca ccatccggca tttttatctg
    17461 tatattatga tttataaacc attggtagat atagccatta atcaatccta aaatcatagc
    17521 aacaaataaa ccttttgatg ccatgaaagc ggtaggcatt cctgctccag cctctcctgt
    17581 aatgaaaggc gtaactgtaa taaaagatga taatgacaca ataccagcag gaataccatc
    17641 aactttgtat tgtctagcca taaagtaagc gataccaaaa ctagctacaa gaccaagtaa
    17701 tccaaaacta ctatcaacac ccttccataa atagtcagca acaccaatat cacctagata
    17761 tttttcccat cctggaatag gaaaacttgc aataaccatt agtaatgaac ctatcaacaa
    17821 taaaggtata gttagagtaa taccgtctcg aatagaaacc aacgctttat tattacccaa
    17881 tctagccgct actggaagta acttttcttg taataatttt tccataacct tttcctctta
    17941 aatatatttt attatcaaaa gttatcaatt atctttattt tttgacgtca agttattatt
    18001 tgattatctt ttgttattta tattttacaa ctataagaaa gccttgtcaa ggatttgtgt
    18061 aaatatttga ttatttttta ttatcaatat ataataaaaa gagaccagta agcaatgaaa
    18121 agcttaaaaa gattaacatc tacatttatc catagcaaaa aatcatagga ttttaagaat
    18181 ctgacaacta ggaagaaaac taatatgacc ttatctaaga aacaattaca actaagagct
    18241 aaaatactgg aaacagttta cacattaggt cccatttcac gaattgaaat cgctactaaa
    18301 acaggaataa cacctgcaac aactagcagt atcacaaatg atctgattaa agaaaatatt
    18361 ctcttagaac ttggtgaaga cgaacacgat acaagcgtag ggagaaaaaa aatcctgcta
    18421 gacattcaag ctaaacgatt ttactacatt ggttgtgaac tatctgaaaa acatttcact
    18481 tttgctttag gagataatct aggaaatatc ttaaaggaag agaaagaaat tgttactaaa
    18541 cagttaatcc aagaaaaggg aaatcaactc attaaccaga cactaaagca attcttaaat
    18601 aactgctctg attatgaaat agaagcaatt ggaatcgcgc tacctggtcg ctatttagat
    18661 gattataaaa taacaacaaa caatccttta tggcaacata tcgacttaga aatgattcaa
    18721 tcccactttg ataagccttt gtttttctct aacaatgtta actgtatggc tataggtaaa
    18781 cgcctattta gtcgccaaca gaatgaccct aattttgctt attttcattt tgctagaggt
    18841 atgcactgtt cttatatcta cgacggaaac atttatggga aaggaaatct aatgattgga
    18901 gaaatagggc atacagttgt ttcatctgag ggagaagaat gtagctgcgg gcgcaaggga
    18961 tgcttacaaa cttttgctgg agaatcttgg ttaatcaaaa aatcaaaaat tctatatcat
    19021 caatctccct attctctact tcctagttta gtcaaaaatg ccgatgatat tgatatccaa
    19081 gttattttaa ccgcttatca attaggtgac actggaataa tcacacttat ccatcaagcc
    19141 ttactctatc ttagtcaaac cattttaaat atcagtatga tgattgactc tcaaaaaatc
    19201 tacctacata gtcctttact aacaaatcaa cacatcatcc aaaaactata tagtgaaatg
    19261 aactacaaac ccaaactgct ctataatcgc ctacctgaag tcattattga accttacaat
    19321 gattttacag ccgcacactc agctattgca ctttgtttgt atcatacaat tctacattct
    19381 taattttcta ttacatttaa taaataggct aaaaagaggg agtatatcat aaaaagcgaa
    19441 taaacctgtt ttctgaaaat cagaattctg ttttgttcgc tttctttata tttggaatta
    19501 tactcctatc tccccttttt cataatgtat agtgaaatga aataataaca ggacgaatcg
    19561 atcgggacag tcaaatcgat ttctaacaat gttttagaaa tagaggtgta ctattctagt
    19621 ttcaatccac tatattttcg tacaggtgct tcaaccattt gaacgatttc aaatccttct
    19681 ttttggtaaa gattctgagc tctttgattt gcctcgaaga catttagaga aatactatct
    19741 atatcttcat tttcaaaggc caaactaaca aatttcctta aagcctggct acctaagtct
    19801 tgctcctgtt tctgggggtt gataaaaaat ctcccgatat gaagattgct gtcttctagc
    19861 ctgattttct ggataagtcc cacaaactct tgttcatcaa agattgaaaa gactccttcc
    19921 aaggcttgaa ggggcagtag aaaaggaatc cttggtccca tccattgttc ttgaaaggat
    19981 ttgcctaggg agttggacca ctggcataca aattgagcgt tttctatact caccttttct
    20041 tcaaaacgaa ttgtcatctt ttcctcacca tcttatctat gtttctccat tatactattt
    20101 ctcccatttt ttacgaatag ataagtatga ttgattttta tttttttctc gtcgggagca
    20161 ttctcgcttc ctttcttggt ttggtcattg accgttttcc agagcaatcc attatcagtt
    20221 cagccagtca ctgcgattcc tgtcagactc ccttgcgtcc cttagatttg attccgattc
    20281 tctcacaggt cttcaatcgc tttcgctgtc gctactgcaa agttcgctat cctgtctggt
    20341 atgccctctt tgaactaggc ttaggactcc tctttctgct ttactcttgg gaattgcttt
    20401 ccttggggca agtcgtccta atcaccgctg gtttgacctt gggtatatac gactttcacc
    20461 atcaggaata tcccttactg gtctggatga ctttccacct aatcctaata gcttcctctg
    20521 gctggaatct ggtcatggtc tccttcctca tacttggaat tttggctcat tttattgata
    20581 tccgcatggg tgcaggggat ttcctctttt tagcttcttg tgctctcgtc tttagcgtaa
    20641 cggagttact gatcttgatt cagttcgctt ctgcgacggg tatcctggcc tttctcctgc
    20701 aaaagaaaaa ggaaagactt cctttcgtgc ctttcctctt acttgctact tgtgtgatta
    20761 tttttggtaa gctactactt gtttgataaa ttccaatttc tgccatatgt actccatgaa
    20821 attatttcac agttaaatta taaattattt cttttgtaca aagggatgat gttatcaaat
    20881 cgatctgttc ttctatcttc ttgatactga tcaaaaaatt tcatttcgac tgaaaatatt
    20941 tcgcttataa actgtaaacg aatactttgt ttagacatta tagtcgctag actgactaga
    21001 tgattactca aaacgacgtc cagaatactc tttactttgc ttggtttttt aacaaaaatt
    21061 tgatcatcca aaggttcaat cattttgtaa cctttttgcg caatttgacg ataaaagtaa
    21121 gaatgttgct ttggagtcaa taatcctaac ttaaaagctc gatactctaa agcctgtatc
    21181 gaaacattca aatccgactt caataaaata taactatcag gattgctgac acgcttgcca
    21241 accctctctt caaatttgac taaaaactct tcttttggca ataaaaaaca tgatgcaaaa
    21301 taatttgctt cttgctccaa acgatcgcca tcttcattca tatctttata tttatgtaaa
    21361 agaatatgtc ctagctcatg agctaaatca aaatttcgac gtacagatga tttattcgtt
    21421 cccaacacaa tataaggtct tcccaatttt gaccatgcgc tataagcatc agcttggcca
    21481 ttaattaatc gttccacgat atagatgcct gaacgttcta atttataaag caaatcatga
    21541 ttatcttttg aaatacctaa tttttccctg gcataaagag ccaattcctc aatggattct
    21601 cccttatgat aagattcact cactacatta cttaggtcat gaattgtaat attaggtata
    21661 attacaaaac tttcaaaata atcaatcaaa ctatctacct tatgtaaata catagtttga
    21721 atatctattg ttttccgggt tgctaggtct gcatttctaa aggcaattac agaagaatca
    21781 aatcgaatgc tctcttcttc ctgttcaaaa taagttaaat caacatgaaa ttggttggcc
    21841 aaatgcattt tggttgataa tttaggtttc gtttcgttgg actcaaactg ccaaatggct
    21901 tgttccgtta aattaattct ctgagctaat tctgctctac ttaaaccatt taacagccgt
    21961 aattctttca atacccgacc attaaacatt tacatactcc ttactacttt tgaccttctt
    22021 gtttttctat tcttggaata atttcaaaat cttctgtttc cgataattct gaaaaattag
    22081 gaatatcttg atatttagct tcttcgaaat ggtacgaact tgattgaata tactcagaca
    22141 aatcttgaat caagtgtaac tgaccagttc gtgcatcagg cataacaaca tctacagata
    22201 taatattgtt ttctgagtcc gcctcataag ttaaaatcat aaatttttcg atattcgaat
    22261 ttttagtagc ttgttcaatt tcttgaatca tttcatcaga aactaactcc atctgaattg
    22321 gaaaggaatg actatcttca tcatttttgt aggaagaatg ttgattaaga taaagtgtat
    22381 tcatctgagc atattcaaat aagtagccac tcttattttt ttgtaccaaa ggaaattggt
    22441 tcgtaagtcg cttcttaccc tttataatta acaatacttt cccatatttt tctgtgtttg
    22501 tttcaaattc taaatatccc caagtctgtc ctgctaattg taatttatac tcaaacaaat
    22561 ctgctgatgc aaatgcagta tcaatatgat taggtcgcgt ccatgcataa ccattcgaca
    22621 ctatcattgt ctctcttttt tctagacgtt catctacata atctttttgc cctttcatca
    22681 aagtatctac aattttttgt gcctcaagcg aatcaaagag atcctgattc aacataattc
    22741 ttcctcctcc aaatactttt taatgaatta tatcattttc ttaaagaaat tactacaata
    22801 attagctttt tcttaaagtt ctgtgtcaga gtaatttaga aaattatatc ttctatagta
    22861 aaatcaatta aaaactgaac aaatttattg ggaaattcaa atcactttct aaaaatattt
    22921 taggaaccgt agtgtaatat tccagattca atttactata aaactagcct ttctcctgca
    22981 aaagaaaaag gaaagacttc ctttcgtgcc tttcctctta cttgctactt gtttaattat
    23041 ttttggtaag ctactgcttg tttgataaag tcctgaatcg gctctccttg gtggagagct
    23101 tttactattt tcgaaccgac gataacacca tctgacaccg cattgaagcg ttccagatcg
    23161 gcttgactag atacaccaaa acctgtcaag actgggatgt cggccacttg atgaagttgc
    23221 gccaagtgct tgtccaaatc tgcacggtaa ttgcctgatt tccctgttac cccattgatg
    23281 gcaacggcat agacgaatcc ctccgcccct tcaatcaact ctttctggcg ctcaattcct
    23341 gtggtcaagc ttactaaagg aatcaaggcg atatctgtat ctgccaaaaa tggttctaca
    23401 aagttggcat gttcatgagg caggtctggg ataatcaagc ccttcacagc tgtatcagcc
    23461 agatctttga caaagttctc cacaccgtac tgaaagaggg ggttgaagta ggtcatgatg
    23521 accagtggaa tctctgtttc aatggttttc aaggtttcaa ctaaagcctg ggtagaggtc
    23581 ccgtgggcta aactgcgcaa gccagcttct tcgataacag gtccatctgc aacagggtct
    23641 gaaaagggaa tacccacttc aattgcagag acacccaaat cttctaaaaa gtgaattgtt
    23701 tcagcaagac catccaaacc tttttcgtgg tcaccagcca tgatataggg aacaaaaatt
    23761 ccttttccag ctgctttaat agcatttaat ttttttgtta gtgtcttagg catgagcttc
    23821 tcccttcttt gctgcatctg cttccaagcg gtcttttact tgaaccacat ccttgtcccc
    23881 acgacctgat aggcatacaa tcatagactt ttctggtcca agttctttgg ccaatttcac
    23941 cgcaaaggcg atagcatggc tagattccaa agctgggata atcccttcca cacgagacaa
    24001 gagttggaat ccttccaagg cttcttcgtc tgtcacaggg acatagctgg cacgtttaat
    24061 atcgtggtag tgagaatgct ctggaccgat accaggatag tccaaacctg ctgagataga
    24121 gaaggcttca agaatttgac catgggcatc ttggagcaca tccatgaggg aaccgtgaag
    24181 gacacctgga cgacccttgg tcaaggtagc tgcgtggtgc tccgtatcca caccaaatcc
    24241 agccgcttca gctccataca tggctactga ctcatcttct acaaagggat ggaagagacc
    24301 gatggcattc gacccaccac caacacaggc tactagggca tctggcagat tttgtcctgt
    24361 caagtcacgg tactgttgtt tagcctctcg accaatgaca ctttggaagt cacgaacaat
    24421 ttctggaaat ggatgaggcc ccaaggcaga accaaggata tagtgggtat catctatatt
    24481 agccacccat gaacgaaggg ctgcattgac cgcatccttg agcacgcgcg aaccatctgt
    24541 cacggcctcg accttagctc ccaaaagctc catacggaag acattgaggg cttggcgttt
    24601 gacatcttcc tcacccatgt agatggtaca ttccatgtta aagagggccg cagcagttgc
    24661 agttgccaca ccgtgctgac cagcaccagt ttctgcgata attttctttt tacccatgcg
    24721 tttggcaagc caaacttgtc ccaaggcatt gttaatcttg tgggctcctg tatggttaag
    24781 gtcttcccgt ttgagataaa tcttggctcc gccgatatgc tgggtcaagt tttttgcgta
    24841 ataaagagga gtttcacgtc ctacgtactg gcgcaaaagc tggtttaatt cctcttggaa
    24901 acttgggtct gcctgacttt cacggtaggc cttctccaac tccaaaactg ctgtcatcaa
    24961 tgtttctggg acaaaacgtc cgccgaattt tccgtaaaat ccatctttat ttggttcctg
    25021 atatgccatg ctttaccctc tctataaatc ttctaatctt ttcatgatct ttttgtccat
    25081 ctgtctccac tccgctcgat acatctactg catagggagt aaaatgttga attgctttta
    25141 ctacattatc ttcattaagg ccacctgcga taaagaaggg ctgtgctagt ccagtcgtat
    25201 ccagttgacc ccaatcaaag gactgaccac ttcctgccac aggggcatca aagagtagat
    25261 aatctgcctg agaattgggg acatgcccat ttccatctac ctgcacagcc tgaatactgg
    25321 cacaaggcaa attctcaaat aaatcagctg ccacctgacc gtgaacttga accaagtcca
    25381 agccaacttt gtcaatcgct tccagcagtt ctacccgact tggtgaaaca aatactccaa
    25441 cctttttcac atctgcagga ataagctttg ccaactcagc tgcctcttct aaagtcacct
    25501 gtcttttact aggtgcaaag acaaaaccga tatagtcggc tcctgctgaa acggctgttt
    25561 ccaccgcttc tttggtcgat agtccacaaa ttttaacctt tgtcaatctg caactccttg
    25621 attctctggg ccacattttc tgcctgcata agagctgtcc ctaccaaaat tccgttaaag
    25681 tatggggcta gtcgttccgc atcctgccct gtgaaaatgg cagattcaga aatgtaatag
    25741 cgaccttcct caaagtaagg ggctaaatct acactggtct gcaagtcgac ctcaaaggta
    25801 gtcaagttgc ggttgttgac cccgataatc tcagcaccaa gtctgtgggc tacctctagt
    25861 tcagctagat tgtgagtctc cactaagact tccagaccaa gctctgtcgc gtagtcatac
    25921 agttccttga ggcgttcttc ggacaaggct gccacaataa gcaagataac tgtcgcacct
    25981 gtattgcgag cgcggatgat ttgcttttca tctatgataa agtctttgtt gagcgtcgga
    26041 atctctacct gactggaaat ttcccgtaga taatccaaat gccctttaaa gaaaacctca
    26101 tctgtcaaca ccgaaatcat cactgctccg ttttcttcat aagtctgggc ctgttgcaca
    26161 atatccacat cgagattgat atctcccaaa ctagggctag ctttcttgac ctcagcgatt
    26221 acctgcaagc agtcctgatg attcttcaaa aattctgcca agcgataggt ctggcgcaga
    26281 ggctggattt gctccagctt catctgctcc acctcacgcg ccttctgctc taagattcgt
    26341 gctaaaaatt cctgactcat ttttggtact cctgtaacag tctgagtttt tcaagggcct
    26401 tgcctctagc aatcacttga cgggccaagg caactccttc cttgatgcta tcaatcttac
    26461 cattagcata gaaaccaaga ccagcattca agactgtcgt ttccaagaat ggacttgctt
    26521 cgtttttcag aacgctaagc aaaatttctg cattttcctg agcattccca ccacgaatat
    26581 cttccatagc atagtcttcc attcccaaat cctctggagt aaagcttgac aagctgattt
    26641 cgccattttc aagaagtgca atcttggttg ttccgttcaa gccagcttca tccaaccctt
    26701 ctggtccagc aaccacgatg gcacgtttgc gacccatatt tttcaaaacc tgagctgtac
    26761 tttctaggag ttctggacga ctaattccaa gaagctgtgt ttctaaagcc attggatgaa
    26821 tcagtggacc agtcaagttc ataatcgttg gaattcccaa ttccaaacga gctggcatga
    26881 tgtatttcat agctgggtgc atatttttag cgaagagaaa gacgattcca gttttatcaa
    26941 agaccttacc tagttcagct ggtttgaggt caagattgat tcccaaggct tcgaggacat
    27001 ctgcggaacc agatttagaa gaaatcgagc ggttaccatg cttggccatg tgaataccgc
    27061 caccagccaa gacaaaggct gcagttgtgg aaatattaaa actgaaagac ttgtccccac
    27121 ctgtaccaca gttgtccata gcatcatgaa tctcagttgg aatatgctgg gcatgtcctc
    27181 tcatgacttg ggcaatggct gtacgttctt caggtgtttc ccccttcatc ttaagagcta
    27241 agaggagaga agcaatctgc gcttcagtta cacgcccagt tacgatacgc tcaatgacat
    27301 ccgtcatttc cacacctgat aaattttcaa attttgctag tttttcaata atctctttca
    27361 tcctagtttc ctcactttac aaccttctcg ataaaattcc gaatagaaga caagccgtct
    27421 ggcgttccaa tgctctctgg atggtactgg aagccataaa tcggtaggtt tttatgttga
    27481 atccccatga tggcttggtc atcagtcgaa cgagctgtca cttcaaagtc ttctggcatt
    27541 tcctcaatca aaatactgtg ataacgcatg accgcacgtc catcctcaat accttgatac
    27601 aaaacagatg gcgcttcaaa gttgatattg ctctgtttcc catgcatgac ttttggagcc
    27661 aaacctagct taccaccaaa gacttctgca atggcttggt gacccaaaca aatccctaga
    27721 atcggcttct tgcctgcaaa atcacaaatc atgtcttcca tctttccagc atcaactggc
    27781 caaccaggac caggagaaaa gaccagacca tctgcttttt cagcttcttc atacagcttg
    27841 gaatcatcat ttctcaaaac ctgaacttct gcaaaattcc caatgtattg ggccaagtta
    27901 taggtaaaag aatcatagtt gtcaatcaat aaaatcatgg tcttagttct ccaattctag
    27961 tcatagattt tgctttgtta atggtttctt ggtattcgtt ttgggcgata gagtcgtaga
    28021 caatccctgc cccagcctgc acataggctc tttgattttt gagaatcatg gttcggatgg
    28081 caatggccaa atccatatca cccgtcgcag acaagtagcc gattgctcct gcatatacgc
    28141 tccgtttttc cgtttccagt tcatagatgc gtctcatagc tcgaattttt ggtgctccag
    28201 aaacggttcc agcaggaagc gttgctttca aggcatccat ggcagtgagt tctgcaagca
    28261 aacgtccctt gaccacactg gtcaaatgca tgacgtagcg gaagagctcc acctccatat
    28321 acttagtaac ttggacactg gccgtttcag agatgcggcc aatatcgtta cgccccaagt
    28381 ctaccaacat tcgatgttct gctgtttcct tctcatcaga gaggaggtca gtcgccaagg
    28441 ccttgtcttc ttcatccgta gcccctcttg gtcgcgtccc tgcaatcgga ttggttgtca
    28501 cgatgccatt tttgacagaa accaaacttt ctggactagc tccgatgatt tgataatccc
    28561 caaaatcata gaaataaagg taattagatg gattagtcac gcggagattt ctgtagaagt
    28621 caaatggatt tccagtaact tctgctgaga aacgctggct gagtacacat tggaacatat
    28681 ctccgttacg aatcaagtca cgagctgttt ctaccattcc ctcaaactta tgtggagcga
    28741 tatgcggttt gaagtcaagt ggtgataaat ccaagtcttc aaattcattt ggagcaggaa
    28801 tgcgtaattc ctcaagcact tggttcaagg atttttccaa ggcctcttga ctgcgctcac
    28861 tataaagtgc atcctctatg acatgtatct tctccttctt gtggtcaaag accatatagc
    28921 tctcatagac aaagaaatgc atgtctggcg tcccaattgt atcctcaggg atttgaccaa
    28981 tttcttcata aagcgaaatc atatcgtaac caacaaaacc aatggctccc ccaccaaaag
    29041 ggaggtctga atggtgctgg ctcttatgag tcacttcata aaggaaatcc aagggatccc
    29101 gatcaatcgc ttgaccattt tgatagagaa ctccattttc aaacttaatc tcaaaaactg
    29161 gattataggc taggatagaa aaacgagctg tttccttgtc tctcggaata ctctctaaaa
    29221 taaccttatg ttgccccttt aagcgcatat aagccaagat tggtgataag acatctccat
    29281 gaatgattcg ttccattgtc atttcccttt cagttctaat tctagttcgt ggcgactgta
    29341 tgaaaaatcc ccacgcaaaa taacttgcgt gaggacgaaa ttcgcggtgc cacctcaatt
    29401 ataggatttc tcctatctct cattcctgtc tcagatatct cctgtaacag gctgtgcgat
    29461 aaagggcact cccttgagaa tgatgttttc ttctctcgtt tcagatgaac ccaactttac
    29521 agctttctct gcttgttttc agcaaccaca agctctctgt gagagaaaag actgtaattt
    29581 ttccatctat tattttttag cttctagtaa tctgcaatcg cagctaggtc cttgcctcca
    29641 cgaccagaga cattgatgaa gagatgttca tctcggtaca cctttatact cttcgaaaat
    29701 ctcttcaaac cgcgtcaacg tcgccttgcc gtaggtatgg ttactgactt cgtcagttct
    29761 atctgcaacc tcaaaacagt gttttgagct gacttcgtca gttctatcca caacctcaaa
    29821 acagtgtttt gagcaacctg cggctagttt cctagtttgc tctttgattt tcattgagta
    29881 ttactagctt ttttcgtatt agtccagcct ttttgtttac ttttagtagg aggcaaggag
    29941 ctgtagatag aactcaagtt catcaaagcg acttaaggcc ctaataaaag ataaaccaaa
    30001 cgacggatag aaaaaagccc acacacagaa tatacttccg tgtgagggcg ttggtaacgc
    30061 ggtgccacct caattataaa gggactatcc ctttacatct ctgccttgtt taacaacaag
    30121 ctgcactgta aggtgtgcgc accgaatttt cattgtttca aattcatttt caaaatcagc
    30181 ccactttcac tacttccaac cacctattca caatcaccac aggctccctg aagatcaaaa
    30241 atagttactt ttctgatttg ttgaacttat tttaatactt tgttttttct ttgtcaagac
    30301 ttttttacga tttttttgat atcattcgaa tgtgaccata tcttccttag atcgaacatg
    30361 aacatgtccc acttgttaga aattggatcc aactcaatag aaactgaatg gaggctaaac
    30421 agaacttatt ttagaacact ccatcttttc cactaggatt ttcaagaatt aaacaatact
    30481 agaaactctg tctcctaaca aatttaggag aaacttcaac agatgtgaca ctttcccctt
    30541 taataattgc taaaacacct tctatcattt ctttagccaa tttaacataa ttgggagcaa
    30601 ttgtagacaa agctggagta taatactgag aaataggaat attatcaaat ccaatgatag
    30661 aaatatcatc tggaataaga attcctttct catagcacgc acgaatcaag ccctgaacct
    30721 tttcatctcc tgaaacaaaa ataatgtccg gataattttg ggtagtcaag tgctgcattg
    30781 cataagaata aactgaatca attgtagata agccataaat gacttttaaa tccataaagt
    30841 aatttttatc attcagaaaa gaacgcacac ctctttcacg atccttatta acatgggatt
    30901 ctcctcccat aagcaaccac atatttttaa atttttcttc agttacagct ttcatcatat
    30961 cataagtagc ttgaaaatta ttattagata catagactac tccagacgtt tgagattcac
    31021 cgaaaacaag aaaaggcata tggttcttct ttaaatactg aattctgata tcatctacac
    31081 tttcataaaa aacaataaca ccatctacta ggctacctgt gcttgatata attgaattac
    31141 taattgtatc ctcctctcca aagtactcaa ctatagcatt aacaccaaat tctttacacg
    31201 tccgtaacac tttatctaac agcgtatgaa accaaattaa aggaaaagag tcgatttttt
    31261 ttacagaaat caatatattt atagcttctt ttttagttaa attttttgca tacgcatttg
    31321 gaatatacga caattcctct ataacttttt gaatcgcttg ataagtttct tctttaacat
    31381 ttactccacc attaataact cgtgaaactg tttttggaga aaaacctgat aaacgtgcaa
    31441 tatcataaat agttaccttt ttcccattta tatttttcat ttcagtcctc cattacgaac
    31501 attctaatat tactatacaa tatttaattt tttttaacaa gagaatttag taaattattt
    31561 aagatccaca aattcacaaa attaatttta caaatattct tccccttcaa aaaaatttaa
    31621 attgcatttc acacctttat ttttaagaat gtttccaact tcacgacaaa taaattcata
    31681 tgagaaaaaa ctgccataaa attgtagatt aactttttca gtaaaatgtg taggatttat
    31741 aaaaacatat aatagcctgt caatgtaaca ttttaacata gagttaattt tttctttaaa
    31801 gataacattt gttatcaact catcaggagg taaatgaaag gcaaacacca tttcacaaat
    31861 atcataaaaa gaaataaatt tgtatacttg tatcaaacaa ttattatcaa aatattctat
    31921 tttacctaaa tcaaaattga ttttataatc tttcataaaa acctctgagc aaaaatctac
    31981 tcaaaaatta gatgattaaa acatctaaaa aacaaaagga caaaaacatc tgtccctttg
    32041 tttactaaat ttcagctaat ttcttcgaca taaataacac ctacaatatt agcaatttct
    32101 tccatcagtc gaagatgttc aaatctacct gataattcca gagtaataaa tgacgctatt
    32161 tttttatctg gaacatcaaa gtattcaatt ctgtcagaat taacatctcc aaacgctgtt
    32221 cttgaatcgg tcattctgat accattttct gcacaataaa ccaatacacg attataggct
    32281 tctgtagatt taaccactat atacaattca atcattttag aacgattttg tagatatttt
    32341 tttagtggtt ggaacatgga tatcacaccc caaacagaaa tggctactaa aagagctccc
    32401 tcataaaaac ctactccaat agctaatcca attcctgccg aagcccaaat gcctgctgca
    32461 gttgtcagac ctgtaatttt ctttttatct gtaataagaa tcgttccagc gcctagaaaa
    32521 cccacacctg atataacttg agctcctaat cgtgtaggat ctcctgtccc aaatttataa
    32581 gatacgtatt cattcgtcat cataatcaaa catgcagcta gacaaacaat actataagtt
    32641 cggatgcctg caggctggga tttgctccct ctctctaaac caattatact accaatgact
    32701 actgataaaa caatcctgac aactatttca atatttgata acccaagact agtggctgtc
    32761 atgattattt ccttacttta cgccccggtc tttgtgtgaa gtataatacc gttccagaaa
    32821 taatcatcag aacaattgta taaacaaata ccagagcttg tgcattagat gttgctgttt
    32881 catcacctgc agatcgaatc gtaataccta atggttgagc taggggatgg taaaggaata
    32941 cagataagtc gaagtcagtt aataaagagt taaagtttaa agcaataaca gagagaacaa
    33001 ccggtaaaat aaatggaatg ataaccttca tcatagtata aaaaggtgaa gcacccatac
    33061 ttcttgctgc atcttccatc tcatcatcaa cactaaataa aatagcacgt accattctat
    33121 aagaaaatgg gatttttaca actatatatg caataagtag aattaccaaa ctacctacca
    33181 aaatctgatt caagacaaga aattgtggct gattaaaagt aaataataaa cttactgcta
    33241 aaagcgtact tggtaataac caaggaagta gagcaccata ttcaaataag aaatcaaaac
    33301 gagatttatg ttttctgaca acacgagcaa atacaactgc gagaattgtt gctgttgtcg
    33361 cagcaataat agaataaata aagctgacca agaatggaga gaatgccgca ctattactaa
    33421 agaataagcg ataattttct aaagtaaagt ttgataatgt taagttacct gtttgaattg
    33481 caactggatc tgtaaatgag tataatacta taaaaattag tggaagcatg aaaactgtga
    33541 acaatccata tgctacaatg tgagcaatga tattccaagg cttagacgca attttttgtt
    33601 ttttaagagg cgctttagtc ttagagatag aaatataatt tccacctttt tctatcttat
    33661 tcatgatagt aagcaaaatt gtagttgcaa tacctaaaat aattgcaagt aaggcagcta
    33721 aatcacgaga attccccatc cctgcaaatg taataatcat tggatttata gtttgaaatt
    33781 ctttaccacc aacaatcatg ggtgctgcta ctgcagataa accactaaga aaaaccataa
    33841 tagtaagtgc aaatagagtt ggaattaagg ttggtaacac tacttttcgg aaaacagtaa
    33901 atggttttgc tcccatattt cgagcagcct caatagtgtg atagtcaacg cttcgaattg
    33961 tatttgttaa aaacaatgta tgattagcag ttcctgaaaa tgtcataatg aataagactg
    34021 caccataccc aataaaccag ttagggtcta aagaagggat aacattttgt aaaaattttg
    34081 taatcaatcc atatggacca tagacaaatt tatatccagt cgctaaaacc actcctccat
    34141 aaattaaaga ggtcatataa cctaatttta aaattttagc acctttaata tcaaagtact
    34201 ctgtaaatag aacacaaaga atacctacga cattaactgt aataatgagt gaaaatgcta
    34261 acttaaaact gttcataata ctctgaagtg ccctctgaga ttttagaaca cgatgtacag
    34321 catcaaggga aaattctcct ccttttacaa atacattcac tactagatca aagtttggat
    34381 aaataataaa tgttactaag aaccagatta accctaaacg aataagccaa tcttttaaat
    34441 ttaatttatg acgcatactg cacctcctta aaattgcaga acgtctgatg gtgtgataaa
    34501 taattccaca ctttctccga cagatctaat agcagcctga ctatcaatac ttgttacatt
    34561 aagaatctga ctttcagaaa cttttattgt atagtgaatt gtaactccag aaaactcaac
    34621 atcaataatt gtccctttta gaatgaaatc ttgttcagtt tcacgattga atcgaacttt
    34681 ctctaatcga atgtatcctt ttttatcttc taagaaaacg cttgtatttt tcagtaatac
    34741 ttcgtggact gtttcatcgg tcaaaacatt aatatctcca ataaaatcac atacaaattc
    34801 agtttgagaa ttatgataaa tctctactgg tgtaccgacc tgttcgatgt atccattgtt
    34861 aaagactgca attctatcag ataaagtcaa ggcttcctct tgatcatgag taacatataa
    34921 agtagtaata cctaactctt tttgaagtct tttcaactct tttctcaaat ctacacgtaa
    34981 ttttgcgtca aggtttgaca atggttcatc tagacaaaga attttaggtt caagaaccag
    35041 agcacgagcc aatgctaccc tttgttgttg acccccagat aattctgata cattacgctg
    35101 taactgttga tcagagatct taatttttgc tgccactgct gatactttag ctttaataac
    35161 atctggagct accttcttaa cttttaaacc aaatgcaata ttatcaaaaa cagtcatagt
    35221 tggaaatagc gcataagatt gaaatacaat accaattcca cgcttttcag gttccaaatg
    35281 agtgacatct gttccattaa cttcaatact tcctgatgat ggatctaaaa aacctaccaa
    35341 tgctctcaaa gtagttgatt taccacatcc tgaaggccca agaaatgtaa agaattcccc
    35401 ttcatgtata tctaaattca gattatcaat tgcaacaaaa tcaccatatt taatttgaat
    35461 attatcaaat ttaatcatct cactaactcc ctctattact aaaccaaaag cctctcttta
    35521 tttcttcctt aaatttagaa ataatagaga gacttggaca taaaaaataa ctcttatttc
    35581 ttattttacg tattctaatt cagctttttc tacccattca tccaaatgct ttccaacagc
    35641 ttcccagtca atattttgtg gtttcacttg atcaacaaat tttttcgtat cttcaggtaa
    35701 ctcttttagg gcatctttat ttgcaggaat agatccaaat tttttactat attctacttg
    35761 aatttctgat tgaccaaacc aatcaataaa ttctttagct aacgcttgtt ttttactagt
    35821 gcttaaaacc atagtttgtt cagttacaaa tggtacacca atctcaggag tcataacttt
    35881 gaattcaaca ttttgttctt tttgtccgat taacgctcca gaaccccaga tcataccgta
    35941 ttgaattggg ctttctttat ctaacgcttt aacaactgag ctttcacctt tttgaagagt
    36001 ataggcattt gcaaagtatt cttttgcaac ttcccatcct ttttctgata cgcctaaatc
    36061 tcctttttca tcaaggtaac gaactaagat acttgctaga attgcccgtc ctgtaccacc
    36121 ttgaagacca taaattgaat atttaccttt atacttacta cctaattcag tccaatcttt
    36181 aggcatttct tttacatcag gcgccccaat taaaactaat ggttgaacaa tcacaggatt
    36241 ataataatta tctttatctg ataaagattg atcaatttta tctaaccatt taggcttgta
    36301 ctgtactagt aatttttgat ctctaatttt atttgagtca acagcaccaa ttccaaatac
    36361 catatctgca actgcattat tcttctcagc aataacacgg tctgctaatt gagcgccagc
    36421 aatatcaacc atttttatat taaaaccagc ttcttttgct ttagcagtta accaatcacc
    36481 acgaccattt gagactgagt tcgaatagat tactaattct tgacttttat cagctttttc
    36541 ttcagatgaa gaagcagtcg tagaatttga acctccagag caagcagcaa gtgtagtaag
    36601 agcaactccc gttgcaagta cagtagacca aactttcatt tttttcatga taagttctcc
    36661 ttttttatta ttttatttaa atttttcgtg atatggaaca aattgtctca tatcttcaaa
    36721 tacagtatag tcaatacggt ttacagtaat agttggaatc ttctctaata aaatttcagt
    36781 taattctgct ctgactttag taaactcttc ttcctcctct tcggttagag gaatccgaag
    36841 atacccaatt gaaatatgga attgatatct atcatgatta gggaaacaaa cacctgcttt
    36901 ttctgagaca taagtacgaa tttcttctaa tctctttgca gaagcttcat ctgcaggttc
    36961 aactagtatg ttttgttttc ccatttcagt tatacgcata tgaatttctt catccaacaa
    37021 tggaaaaatt tcaagttgtt tagcaaagta atcatgtatt tcctgtaaag gtgtatctag
    37081 aggaagatta ctgctccaaa actccgtttc acgattttca tggcacaaca attcaattac
    37141 agtcatgtga atagaattcc ttggagttaa agtaaactta tcgataaatg gtaattctct
    37201 ataacgtgat tgaataatat caacaacttc catcaaatct tgtttagtat aaagatttgc
    37261 tacaactgta ttcccaggga aatgattaaa ttccccattc tctttgaact taatttttgt
    37321 taagtttttc atataaagac cttctttttt atatttgaca tcggtgtcat tgtgtttaca
    37381 ttatacaatg aaaccgtttc ctttgtcaag cgctgtcaaa catttttttt aatttatctt
    37441 tcattaaaag
//
LOCUS       DAVBCA010000017        34347 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.017, whole genome shotgun sequence.
ACCESSION   DAVBCA010000017 DAVBCA010000000
VERSION     DAVBCA010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34347
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.017"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..4786
                     /locus_tag="VQU19_000778"
     CDS             <1..4786
                     /locus_tag="VQU19_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET2480052.1"
                     /translation="QGERGLTGAKGEKGDQGERGLTGAQGEKGDRGERGLTGAKGEKG
                     AQGQAGRDGVTPTVTVKDNKNDGTHTITINDGRGNVTSTVVRDGFDGASPLVATQRND
                     ADKTTTVIFYYDKNGNNELDASDKKLKEVVIADGAKGEKGDKGEQGLQGRDGEQGPKG
                     EDGKTPTVKVTDGQDGTHTITINDGKGGITTTVVRDGFDGASPLVSTHRNEADKTTTV
                     IFYYDLNDNNQFDEGDTKLKEVVIADGKQGPKGDKGDNGKDGFTPEVTVTDNNNGTHT
                     ITITQPDNRPSLTTIVKNGEDGKTPKVKAERDDAKKQTTLTFYIDKDGDGSYTAGKDE
                     LVQTTVVKDGQDGAAGASGRDGKEVLNGKVDPTTEGKDGDTFVNTQTGDVFVKKGNTW
                     EPAGNIKGPKGDKGADGAKGEKGAQGERGLTGAQGVKGEKGDQGERGLTGSKGEKGDQ
                     GERGLTGAQGAKGDKGEQGLQGRDGAQGPKGADGQRGPAGPQGPKGEQGNPGTPGKDG
                     KSLIAVKNGTETKVYVEDPARPGQPLNPNQPLATITDGRNGTNGQSPTITATRSVQNG
                     KNGVLVTITPVGGRPQTTFVEDGQKGADGKTPTVTITEGQNGTHTLTVHNPGSPDVTT
                     TIRDGATGQAGRDGKDVLNGKVNPQPNQGKNGDKYINTETGDVYVKNNGNWDKEGNIK
                     GPKGDKGADGAKGEKGDQGERGLTGAQGAKGADGAVGRDGRDGKDVLNGKANPEAHQG
                     KDGDKYVNTETGDVFVKNNGNWDKEGNIKGPKGDKGERGEDGKTPEVTVTPGKDGHST
                     DITFTVPGKDPVTVNVKDGENGLNGKTPKVDLLRVQGKNGNPSHTIVTFYTDENNDGK
                     YTPGTDELLGSEMIKDGAKGADGRDGKSLLTVKDGKETKVYQEDPANPGQPLNPEKPL
                     AVIRDGVDGKSPTVTAVRKDEAGHKGVEITVDNHDGSQPTTVFVQDGAKGETGATGQD
                     GQTPTITTQRGQDGQSTVVTITTSGKDPVTFTVKDGKNGKDGRAPKIKVEDITSPSRI
                     RRDTDAAATPTRNGIRVTVYDDVNDNGVYDEGVDKVLNSKDIYNGIDGRDGSAPTITT
                     KDNGDGTHTITVQNPDGSESTTVVKDGKDGKTANITTTENPDGSHTITVTNPDGSTKE
                     TVVKNGKDGKTPKVEVTDNNDGTHTVKVTDGDGNVTNAIIKDGKDGKAATATTTENPD
                     GSHTVTITNPDGTKNEFVVKNGRDGVDGRTPTASVRDNGDGSHTIVITNPEGVTTETT
                     VRDGKSPKVTITDEQNGTHKISVLNGDGTTTTTTVRDGREPKLEVIDNNDGSHTIKVT
                     GADGKGTTTTIFDGKSPKANIVDNGDGTHTLTIVDSDGREYKSIIKDGKDGKDSVSPT
                     VTVKNNNDGTHVVTITNPDGSKTEMVIKDGKDGKSPKVSVEDNGDGSHTITIINSDGT
                     VTKTVIKDGRDGRDGRDGKDGKDGKDGKCGCQDKPVTPSNDKPVPPTPNVPTPEVPVK
                     PVPAQPTPNVPTPEVPVQPTPAVPTPEVPVKPVPAVPEQPVVPTPAQPATPVNANPVA
                     PTTGKENRGDKLPETGSQSDYISVLLGSGILLSLYVGRRKEA"
     gene            complement(5023..5571)
                     /locus_tag="VQU19_000779"
     CDS             complement(5023..5571)
                     /locus_tag="VQU19_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET2480053.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIQ"
     gene            5892..6380
                     /locus_tag="VQU19_000780"
     CDS             5892..6380
                     /locus_tag="VQU19_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HET2480054.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKIIFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            6377..7564
                     /locus_tag="VQU19_000781"
     CDS             6377..7564
                     /locus_tag="VQU19_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET2480055.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAAVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTVILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            7557..7922
                     /locus_tag="VQU19_000782"
     CDS             7557..7922
                     /locus_tag="VQU19_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET2480056.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGLEAGGRDNGAPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            7938..9284
                     /gene="asnS"
                     /locus_tag="VQU19_000783"
     CDS             7938..9284
                     /gene="asnS"
                     /locus_tag="VQU19_000783"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HET2480057.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            9437..9727
                     /locus_tag="VQU19_000784"
     CDS             9437..9727
                     /locus_tag="VQU19_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HET2480058.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            9739..10209
                     /gene="ssbA"
                     /locus_tag="VQU19_000785"
     CDS             9739..10209
                     /gene="ssbA"
                     /locus_tag="VQU19_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HET2480059.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            10241..10480
                     /locus_tag="VQU19_000786"
     CDS             10241..10480
                     /locus_tag="VQU19_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HET2480060.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            10775..12175
                     /locus_tag="VQU19_000787"
     CDS             10775..12175
                     /locus_tag="VQU19_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HET2480061.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSYVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDVIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            12177..12536
                     /locus_tag="VQU19_000788"
     CDS             12177..12536
                     /locus_tag="VQU19_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HET2480062.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            12590..13339
                     /locus_tag="VQU19_000789"
     CDS             12590..13339
                     /locus_tag="VQU19_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HET2480063.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPYSNLNESEHYLLARHEITTNLEEICHSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            13329..13628
                     /locus_tag="VQU19_000790"
     CDS             13329..13628
                     /locus_tag="VQU19_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HET2480064.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDMRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALFKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            13699..14634
                     /locus_tag="VQU19_000791"
     CDS             13699..14634
                     /locus_tag="VQU19_000791"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HET2480065.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            14721..15233
                     /locus_tag="VQU19_000792"
     CDS             14721..15233
                     /locus_tag="VQU19_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HET2480066.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGAVCQEPADFFESNHLYDLYVYPEMDIQSVKERACRHLGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            15270..15865
                     /locus_tag="VQU19_000793"
                     /pseudo
     CDS             15270..15865
                     /locus_tag="VQU19_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
     gene            15966..16160
                     /locus_tag="VQU19_000794"
     CDS             15966..16160
                     /locus_tag="VQU19_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HET2480067.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTK"
     gene            complement(16206..17651)
                     /locus_tag="VQU19_000795"
     CDS             complement(16206..17651)
                     /locus_tag="VQU19_000795"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HET2480068.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVIFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVDIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTATYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVHRVYGLTFDVGVFLNITPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            17757..19379
                     /locus_tag="VQU19_000796"
     CDS             17757..19379
                     /locus_tag="VQU19_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HET2480069.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            19583..21541
                     /locus_tag="VQU19_000797"
     CDS             19583..21541
                     /locus_tag="VQU19_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2480070.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGFLQNLGLEPGEANDKAKAVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFATAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            21713..22648
                     /locus_tag="VQU19_000798"
     CDS             21713..22648
                     /locus_tag="VQU19_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2480071.1"
                     /translation="MKLKLLRVDTKVIMGSFLLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKKIAKIRKKVIEGLIYAEKSFFDKSQS
                     GELTSAIVNDTSVIREFLITTFPNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMM
                     FIILLLSNISEKYSRRLQEEIGFLTGQLTEKIQEHELIKTNQAEKSVQDVLDNCIERV
                     QNNSLKSDRVTSFETPFALLFIFATIAVMLTYGGYRVSAGYISVGTLVSFLIYLFQLL
                     NPISNIANFVTVYSRSKGSSVALENLLAVPKEKFE"
     gene            22673..23325
                     /locus_tag="VQU19_000799"
                     /pseudo
     CDS             22673..23325
                     /locus_tag="VQU19_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864981.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            23483..24577
                     /locus_tag="VQU19_000800"
     CDS             23483..24577
                     /locus_tag="VQU19_000800"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HET2480072.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGRFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            24585..25751
                     /locus_tag="VQU19_000801"
     CDS             24585..25751
                     /locus_tag="VQU19_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET2480073.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEIQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDGLFEIDFDQLEKDLVEEE
                     VKLYILCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKR"
     gene            25844..28942
                     /locus_tag="VQU19_000802"
     CDS             25844..28942
                     /locus_tag="VQU19_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET2480074.1"
                     /translation="MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDSFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLNRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVPDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQNIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPLQATQVKADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSEFYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            28990..29607
                     /locus_tag="VQU19_000803"
     CDS             28990..29607
                     /locus_tag="VQU19_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HET2480075.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPIAEEKPVKPIEKQVGKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            29617..30951
                     /locus_tag="VQU19_000804"
     CDS             29617..30951
                     /locus_tag="VQU19_000804"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HET2480076.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLLRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFSGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            30961..31425
                     /locus_tag="VQU19_000805"
     CDS             30961..31425
                     /locus_tag="VQU19_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2480077.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQYLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     DLDYKGIRLESPDELLSYFEMNGFVDEEATLLYATSQGYSMIWFNPFYLEEQ"
     gene            31422..31916
                     /locus_tag="VQU19_000806"
     CDS             31422..31916
                     /locus_tag="VQU19_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2480078.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            31997..33646
                     /gene="mltG"
                     /locus_tag="VQU19_000807"
     CDS             31997..33646
                     /gene="mltG"
                     /locus_tag="VQU19_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HET2480079.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMTDSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDIIS
                     DTSRRSRREGAKPVNPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPIDA
                     NSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQKSM
                     STEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQAVGQLQGDFKESLTAEAFLA
                     KVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDEML
                     AAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDMPL
                     QSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIESSI
                     NQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            33717..34199
                     /gene="greA"
                     /locus_tag="VQU19_000808"
     CDS             33717..34199
                     /gene="greA"
                     /locus_tag="VQU19_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HET2480080.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
BASE COUNT        10715 a         6373 c         7776 g         9483 t
ORIGIN      
        1 ccaaggtgaa cgcggtttaa ctggagctaa aggtgaaaaa ggggaccaag gtgaacgcgg
       61 tctcactgga gcccaaggtg aaaaaggaga ccgaggcgaa cgtggtttaa ctggagctaa
      121 aggtgaaaaa ggagcccaag gtcaggcagg tcgtgacggt gtaactccaa ccgtaaccgt
      181 taaagataat aaaaatgacg gcactcatac tatcactatt aacgacggta gaggtaatgt
      241 tacaagtact gttgtaagag atggtttcga tggcgcaagt ccattagttg cgactcaacg
      301 aaatgacgca gataagacaa caactgttat cttctattac gataaaaatg gaaacaatga
      361 attagatgct tctgataaga aattaaaaga agttgtaatt gcagatggtg ctaaaggtga
      421 aaaaggggac aaaggtgaac aaggtcttca agggcgtgat ggtgaacaag gaccaaaagg
      481 agaagatggg aaaaccccaa cagttaaagt aactgatggt caagatggaa cgcatacaat
      541 tacaattaac gatggtaaag gtggtataac tactacagta gtaagagatg gatttgatgg
      601 tgcaagccct cttgtttcta ctcatagaaa tgaagcagat aaaacaacaa ctgttatttt
      661 ctattatgat ctaaatgata ataatcaatt tgatgaagga gatacaaaac ttaaagaagt
      721 tgttatcgca gatggaaaac aaggaccaaa aggtgacaaa ggtgataacg gaaaagatgg
      781 attcacacca gaagtaacag ttacagataa caataacgga acacacacca tcacaatcac
      841 acaaccagac aacagaccat cattaacaac aatcgttaaa aacggtgaag atggaaaaac
      901 accaaaagtc aaagcagaac gagatgatgc gaagaaacaa acaacattaa cattctacat
      961 tgacaaagat ggagatggaa gttacacagc aggaaaagac gagttagttc aaacaacagt
     1021 agttaaagac ggacaagacg gagctgcagg agcatctgga cgtgatggaa aagaagtatt
     1081 aaacggaaaa gtagacccaa caacagaagg taaagatgga gacacattcg taaatacaca
     1141 aacaggagat gtattcgtta agaaaggtaa cacttgggaa ccagcaggaa acatcaaagg
     1201 accgaaaggt gacaaaggtg cagatggtgc caagggtgaa aaaggagccc aaggagaacg
     1261 cggcctgact ggagcgcaag gtgtcaaggg tgaaaaggga gatcagggtg aacgcggtct
     1321 aactggatct aaaggtgaaa aaggagacca aggtgaacgc ggtttaactg gagcgcaagg
     1381 tgccaaaggt gacaaaggtg aacaaggtct tcaaggtcgt gatggagctc aaggaccaaa
     1441 aggcgcagat ggacaaagag gaccagcggg accacaagga ccaaaaggag aacaaggtaa
     1501 tccaggaact ccaggtaaag atggaaaatc tctaattgct gttaaaaatg gaactgaaac
     1561 aaaagtctat gtagaggatc cggctagacc aggacaacca cttaatccaa accaaccatt
     1621 agcaactatc actgatggaa gaaacggtac taatggacaa tcaccaacaa ttacagcgac
     1681 acgaagtgtg caaaatggca aaaatggtgt attagtaaca attacaccag taggaggtcg
     1741 tccacaaaca acatttgtag aggatggaca aaagggtgct gatgggaaaa ccccaacagt
     1801 aacaataact gaggggcaaa acggcacaca tacattaacg gttcataatc caggaagtcc
     1861 agatgtgaca actacgatcc gtgatggagc tacaggacaa gcaggtcgtg atggtaaaga
     1921 tgtattaaac ggaaaagtaa atccacaacc aaaccaaggt aaaaatggag ataaatatat
     1981 taataccgaa accggtgatg tctatgttaa aaacaatgga aactgggata aagaaggcaa
     2041 catcaaaggc cctaaagggg acaaaggtgc agatggtgct aaaggcgaaa aaggagacca
     2101 aggcgaacgc ggcctaactg gagcgcaagg agctaaaggt gcggatggcg cagtaggtcg
     2161 tgatggacgt gacggtaaag acgtgttgaa cggcaaagct aacccagaag cacatcaagg
     2221 taaagacggc gataaatacg ttaatacaga aacaggcgac gtcttcgtta agaataacgg
     2281 caactgggat aaagagggca acatcaaagg ccctaagggt gacaaaggtg aacgcggaga
     2341 agatggtaag actccagaag taactgtaac tccaggtaaa gatggccata gtactgacat
     2401 tacattcact gttccaggta aagatccagt tacagtaaat gttaaggacg gagaaaatgg
     2461 tctgaacggt aaaactccaa aagttgattt acttcgtgtc caaggaaaaa acggaaatcc
     2521 atctcataca attgtgacat tctatacaga tgaaaacaat gacggcaaat atacaccagg
     2581 aactgatgaa cttctaggtt cagaaatgat taaagatggt gctaaaggcg cggacggacg
     2641 agatggtaaa tcattgctta ctgtcaagga tggtaaagaa actaaagttt accaagaaga
     2701 tccagctaac ccaggacaac cattaaatcc agaaaaacca cttgcggtaa ttagagatgg
     2761 agtagatgga aaatcaccta cagttacagc tgttcgtaaa gatgaagcag ggcataaagg
     2821 tgtagaaatc actgttgata accatgatgg ttcacaacca actacagtct ttgttcaaga
     2881 tggtgctaag ggagaaactg gtgcaaccgg tcaggatgga caaactccta caatcactac
     2941 tcaacgtgga caagatggcc aaagcactgt tgtaactatc acaacatcag gtaaagatcc
     3001 agtaaccttc actgtaaaag atggtaagaa tggtaaagat ggccgtgcac cgaaaatcaa
     3061 agtagaagat attacttcac cttcaagaat tagacgcgat acagatgctg ctgcaactcc
     3121 aacgcgtaac ggtatccgtg ttacagttta tgatgatgtt aatgacaatg gggtatacga
     3181 cgaaggtgtc gataaagtat taaatagtaa agatatttat aacggtatag atggacgtga
     3241 tggttcagct ccaactatta ctacaaaaga taatggagat ggaactcaca ctatcacagt
     3301 tcaaaaccca gatggttctg aatcaacaac agttgttaaa gatggtaaag acggtaaaac
     3361 tgcgaatatc actacaacag aaaacccaga tggaagccac acaattacgg tgacaaatcc
     3421 agatggttca actaaagaaa ctgttgttaa aaacggtaaa gacggtaaga ctcctaaagt
     3481 tgaagtaacg gataacaacg atggaactca tactgttaaa gttacagatg gagacggcaa
     3541 tgttaccaac gctatcatca aagatggtaa agacggtaaa gctgcaacag caacaactac
     3601 tgaaaatcca gatggaagcc acacagtaac aatcactaac ccagacggaa ctaagaatga
     3661 gtttgttgtt aagaatggac gtgacggtgt tgacggacgt actccaaccg catctgttcg
     3721 tgataatgga gacggaagtc atacaatcgt tattacaaat ccagaaggtg tgacaactga
     3781 aaccacagtt cgtgatggta aatcaccaaa agtgactata actgatgaac aaaatggaac
     3841 tcataagatc tctgttctaa atggtgacgg aacaactaca acaactacag ttcgtgatgg
     3901 tagagaacca aaacttgaag ttattgataa caacgatggt tcacacacta ttaaagtgac
     3961 aggtgctgat ggtaaaggaa cgacaactac aatctttgat ggtaaatcac caaaagcgaa
     4021 catcgttgat aacggagatg gaactcatac attaacaatc gtagattctg atggtcgtga
     4081 atacaaatct attatcaaag atggtaaaga cggcaaagat agcgtttcac caactgtaac
     4141 tgttaaaaat aataacgatg gaactcacgt tgttacaatc actaatccag atggaagtaa
     4201 gacagaaatg gtgattaaag acggtaaaga tggtaaatca ccaaaagttt ctgttgaaga
     4261 taatggtgat ggtagtcata caatcacaat catcaattct gatggaactg tgacaaaaac
     4321 agttattaaa gatggtagag atggacgtga tggtcgagac ggcaaagacg gtaaagacgg
     4381 taaagatgga aaatgtggat gccaagacaa accagtaaca ccatcaaatg acaaaccagt
     4441 tcctccaaca ccaaatgtgc cgacaccaga agtaccggtt aaacctgtgc cagcgcaacc
     4501 aacaccaaat gtaccgacac cagaagtgcc agtacaacca actccagctg ttccaacacc
     4561 agaagtaccg gttaaaccag taccagcggt tccagaacaa ccagtagtac caacaccggc
     4621 tcaaccagca actccagtaa atgctaaccc agtagcacca actacaggta aagaaaaccg
     4681 tggggacaaa ttacctgaaa ctggaagcca atctgattat atctctgttc ttttaggtag
     4741 cggtattcta ttgagcctat atgtaggacg aagaaaagaa gcttaatcag ccaaaagcag
     4801 tcactaattt ctcgaaagaa gatgataagt gatagatctc gaatgaaaga atattcttag
     4861 aatgattttc ctatgatgga aaagactgct aaaaaccttg agtggtaacg ctcaaggttt
     4921 ttttggatgg ctgatgtttg tctgaaaatc ttgattgaga aataaaaagc caccctatta
     4981 ggtggctata attgatttag actttctaaa attttctatt ttttactgaa tcgcttcgac
     5041 caagtcttga gcttgttttt caagtgagtt taggactgtt tcttcaagaa ccaattttcc
     5101 gtctgcccag gcagagtcat taacacgtgc agcagtgaaa tcaccaacgc cttgtgtacg
     5161 gataaatggc aagaggtctt tgtagatagc gaaaagttga tcgtgccctg cattggctac
     5221 agatgatacg gtgacaaact tgtcttgaag ggcagaaacg ccacgcgtat cagacaagtc
     5281 aagggcacga gatagccagt caagcaagtt ttttactgta ccagggatag agaagttgta
     5341 gactggagag aaaatccaga tagcatccgc aacgagaact gcttcacgag cagcagctac
     5401 agctggatgt gttggaactt ccaaatcttg gctgaagaga ggaagggctg aataatcaag
     5461 gtagctaact tccgctttac cagcaagtgc tttctcagct tcgagcgcca tttggtggtt
     5521 gaaagaacct tgacgtagtg atccgacgat aaataatact tttttagaca tgatgtgtct
     5581 cctttttctt caaattttga gaactctctc gttgttataa aatacattac aacaaaacaa
     5641 aagaacttgc aagaaatttg ctcagagttt atttgaaaat tgtaaaattt cggaaactct
     5701 agtcatttgt gactgaaaaa gtaagaactg tttcactttc aaaatcggtt ttgtttgaag
     5761 ggagaaatag aattggttgc tcaaagcaca gctttgaggt tgcagataaa gctgacgtgg
     5821 tttgaagaga ttttcgaaga gtattcttat attcacttgt aataaagctt aatagatggt
     5881 aaaatagacg agtgaaaaaa agacaaaaca aagcaaaaaa taatctactg tggcagtatg
     5941 gtctagggat gacgattttg tttgtggtta tcagtgcttc ctttctgtat atggtttctc
     6001 ttagcatgaa accctatcaa acagctaaaa gtgaaggaga aaaattagct cagcagtatg
     6061 caggattaga gcaggccgat caggttgatt tatacaatgg cttggaatct tattacagcg
     6121 ttcttggtcg taataaacag caagaagcac ttgctgttct gattggaaaa gatgatcata
     6181 agatttacgt ttatcagcta aatcagggtg tttcacaaga aaaagcagaa acggtttcta
     6241 aggaaaaggg agctggcgaa attgacaaga ttatctttgg tcgttatcaa gataagccaa
     6301 tctgggaagt caagtcagga tctgattttt atctagtaga ttttgaaaca ggagcattgg
     6361 tcaacaagga gggcctatga aattatccaa ccgtgtttta gaaatggaag aaagtgtgac
     6421 tttggctgct ggagcccgtg ccaaagcact gaaggctgag ggtagagata ttttgtctct
     6481 aaccttgggt gagccagatt tcactactcc caaaaatatc caagatgccg ccattgcatc
     6541 gattcgagat gggcgtgctt ctttttatac agtaacctca ggtctgccag agcttaaggc
     6601 ggcggtcaat agctactttg agcgctttta cggctattct gtagcgtcaa atcaagtgac
     6661 agtcgctgcg ggagccaaat attctctcta taccttcttt atggctgtgg tcaatccagg
     6721 tgatgaagtc atcatcccaa ccccatactg ggttagctat ggagatcagg tcaagatggc
     6781 agaaggcgtt cccgtctttg tttctgctaa ggaagacaat cactttaagg tgaccgtaga
     6841 gcagttagaa gcagctcgca ctgacaagac caaggttttg gtgctgaatt cgccatctaa
     6901 tcccacaggt atgatttaca cccgtgagga actcttggca attggaaact gggctgtaga
     6961 aaatgatatt ctcatcctag cagatgatat ctatggccgc ttggtttata atggtcatga
     7021 gttcacaccg atttctagcc tatcggaagc gattcgcaag caaacagtgg tcatcaatgg
     7081 tgtgtctaaa acctatgcca tgactggttg gcggattggt tatgccgttg gagaagcaga
     7141 cattatcgct gccatgtcca agattgcagg tcaaacaact tcgaatccgt cagcagtagc
     7201 ccaatatgca gcagttgagg ctctatcagg tgagcaagat actgtagaaa gcatgcgtca
     7261 ggcctttgaa gaacgtctta ataccatcta tcccctcctt gcagaagtgc caggatttga
     7321 agtggtcaaa ccgcaagggg ccttctatct cttcccaaat gtcaaaaagg ccatggagat
     7381 gaaaggctac acggatgtga cagactttac aactgttatc ttagaagaag ccgaagtggc
     7441 cttggtaaca ggagctggat ttggagcacc agaaaatgtc cgcctcagct atgcgacaga
     7501 cctagacacg cttaaagaag cagtcgaacg cttgaaagca tttatgggta gtgagaatga
     7561 ttgatcattt tgagattaag gtaaaggatt tacaaatttc agaaggattt tataggagtt
     7621 ttctcgctcc tttggactat aaattggctt ttaagactag ttctctaatt agttttctat
     7681 ccccgaacag ccctcatcct ggtggtgatt tttggctgac tcagggaaca caagatcctg
     7741 ttcattttgc ttttttagca gaaaataagg aagaagttca ggcttgttat gaggctggct
     7801 tagaggcagg tgggcgagac aatggggctc ctggttatcg aagtgagcat ccgatttact
     7861 atgctgcttt tatgattgac ctggatggga acaatataga ggtggtttgc cataaagaat
     7921 aaaaaagaaa aggaaaaata atgacaaaac gtgtaacgat tattgacgta aaagactatg
     7981 ttggtcagga agtgacgatt ggcgcttggg ttgccaacaa atcaggaaaa gggaaaatcg
     8041 ctttcttaca attgcgtgat ggaacagcct tctttcaagg tgtggctttt aaaccaaact
     8101 ttgtcgaaaa atttggtgaa gaagtgggac ttgagaagtt tgatgttatc aaacgcttga
     8161 gccaagaaac gtctgtttat gtgacaggta ttgtcaaaga ggacgaacgt tctaaatttg
     8221 gctatgagtt ggacatcaca gacatcgaag tgatcggtga atctcaagac tacccaatca
     8281 caccaaaaga acacggaaca gactttttga tggataaccg tcacttgtgg ctacgctctc
     8341 gtaagcaagt agctgtgttg caaatccgta acgctattat ctatgcaact tatgagttct
     8401 ttgacaagaa cggttttatg aagtttgaca gcccaattct ttcaggaaat gcggcagaag
     8461 attctacaga actctttgaa actgactact tcggaacgcc agcctacttg agccaatcag
     8521 gtcaacttta cctagaagca ggggctatgg ctcttggtcg tgtctttgac tttggtccag
     8581 ttttccgtgc tgaaaaatca aaaacacgcc gtcacttgac tgagttctgg atgatggatg
     8641 ctgagtactc atacttgaca catgatgagt cgcttgactt gcaagaagct tatgtgaaag
     8701 ctcttctaca aggtgttctt gaccgcgcgc ctcaagcctt ggaaaccttg gaacgtgata
     8761 cagaactctt gaaacgctac attgcagagc cattcaaacg tatcacttac gatcaagcca
     8821 ttgacctctt gcaagagcat gaaaatgatg aagatgctga ctacgagcat cttgagcatg
     8881 gtgatgactt tgggtcacca cacgaaactt ggatttcaaa ccactttggt gtgccaacat
     8941 ttgtcatgaa ctatccagca gccatcaagg ccttctacat gaaaccagtt cctggaaatc
     9001 cagagcgcgt gctttgtgca gacttgcttg ctccagaagg ctatggagaa attatcggtg
     9061 ggtctatgcg tgaggaagat tacgatgccc ttgtcgctaa gatggatgaa cttggcatgg
     9121 atcgtacaga atatgaattc taccttgacc ttcgtaaata cggtacagtt ccacacggag
     9181 gatttggtat cggtatcgaa cgtatggtaa ccttcgcagc aggaacaaaa catatccgtg
     9241 aagctattcc attcccacgt atgttgcacc gtatcaaacc ataagaacag gaaaacgccc
     9301 atgtggcgtt ttttcgaatt ctagtgtttt tacttgcgta aaaaaaattt ttctagtata
     9361 atagtttatt gtgagcgaac ctcacttacc ccttgcaaag tcttggggtc attagaccaa
     9421 aaggaggaac atatcaatgg ctaaatacga aattctttat atcattcgtc caaacattga
     9481 agaagaagct aaaaacgctt tggtagcacg ttttgactct attttgactg acaacggtgc
     9541 aactgttgtt gaatcaaaaa cttgggaaaa acgtcgtctt gcatacgaaa tccaagattt
     9601 ccgtgaagga ctttaccaca tcgttaacgt tgaagcaaat gacgatgcag ctcttaaaga
     9661 gtttgaccgt ctttcaaaaa tcaacgctga cattcttcgt cacatgatcg tcaaaattga
     9721 cgcgtaagaa ggtaaactat gattaacaat gttgtacttg tagggcgtat gacacgtgac
     9781 gctgaattgc gttatacccc atcaaatgta gcagttgcga cttttactct tgcagtaaac
     9841 cgtacattta agagtcaaaa tggtgaacgt gaggctgatt ttatcaatgt cgttatgtgg
     9901 cgccaacagg ctgaaaatct tgctaactgg gctaaaaaag gctcacttat cggggtgaca
     9961 ggtcgtatcc agactcgtag ttacgataac cagcaaggac aacgtgtcta cgtgacagag
    10021 gtcgtggctg agaatttcca aatgttggaa agccgtagtg tgcgtgaggg tcacacaggt
    10081 ggagcttact ctgcaccaac tgcaaactat tcagcaccta caaattcagt accagacttt
    10141 tcacgtaatg aaaatccatt tggagcaaca aacccattgg atatttcaga tgatgattta
    10201 ccattctaat ggacaactaa acttataaag gagaaaaaac atggctcaac aacgtcgtgg
    10261 cggattcaaa cgccgtaaaa aagttgatta catcgcagca aacaaaattg aatatgttga
    10321 ttacaaagat actgagcttc ttagccgttt cgtttcagaa cgtgggaaaa tccttcctcg
    10381 tcgtgtaaca ggaacttcag ctaaaaacca acgtaaagta acaacagcta tcaaacgcgc
    10441 tcgcgtaatg gctttgatgc ctttcgtaaa cgaagattaa agaaaagacc cggttgggtc
    10501 tctttttcat gaacttgaaa acaagaaagc gaattaagac cccaacgggt cttttttcac
    10561 aagctttgaa atgagagagc gagttaggct cagtggctcc ctttttacga gtttgaaaac
    10621 aagagaacac attaaaagca cgatggagct ttttcataaa tatgtctttt ttttcatcca
    10681 agaaattaaa ataaaaatga taaacttttt gaaaataggg gatttgccta ctttatgata
    10741 taatggaaag agttagattg aaagaggtag tgagatggac gcgaaattaa gatacaaggc
    10801 aaagaagatc aagattgtct tttttgatat tgatgataca ttgcggaatt caaagacagg
    10861 gtttattcca actacaattc ccactgtttt taaacagttg cgtgaaaaag gaattttaac
    10921 aggaatcgcc tctggacgtg gcatttttgg tgttgttcca gagattcgtg atctcaaacc
    10981 tgactttttt gtaactttga atggggctta tatcgaagat aaaaaaggtc aggtcattta
    11041 tcagcatcag attgaaaagt catatgttga ggagtatatc tcttgggcta agcaagaagg
    11101 aattgagtat ggcttggttg ggagtcatga tgccaagttg tcgactcgca ccgatatgat
    11161 gagtgaagct atcaatccaa tttatcccga cttagatgta gatcccgatt tccatgaaaa
    11221 agaagatatc tatcagatgt ggacttttga agataaggga gatgacttgc acttgcctga
    11281 cagtctctca gacaaacttc gcatggttcg ttggcatcaa cattcgtctg atattgtgcc
    11341 gatttcaggc tccaaagcga cgggggtgga aaaggttgtg gaacaccttg gcttgaaacc
    11401 agagaaggtc atggtttttg gagatggtct caatgacttg gaactctttg attatgctgg
    11461 aatcagcgtt gccatgggaa tttctcatga taaaatcaaa gaaaaagcag attatattac
    11521 aaaaacatta gaagaagatg gcatttttga tgccttagaa gtatttggta tggtagaaaa
    11581 agaattgcat tttccacaag tagacattga aacagtagaa ggtcctcttg cgactattaa
    11641 gaccaatcac ggagacttac gtatcaagct tttccctgaa catgctccta aaacagtggc
    11701 taactttgta tctctttcaa aagatggcta ctatgatggt gtcattttcc accgtattat
    11761 caaggacttt atgatccaag gtggagaccc aactggaact ggtatgggtg gcgagtcaat
    11821 ctacggcgaa tcttttgagg atgaattctc agaagagctt tacaatatcc gtggtgctct
    11881 ttccatggca aatgctggtc caaataccaa cggcagccag ttctttatcg tgcaaaacca
    11941 acacctacct tattctaaga aagaaattac tcgtggtggt tggccagaac cgattgcaga
    12001 aatctatgcc aatcaaggtg ggacacctca cctagaccgc cgtcacacgg tttttggtca
    12061 gttagctgat gaagcatctt acgctgtctt ggatgtcatt gctgctgttg agacaggagc
    12121 tatggacaag ccagttgaag atgttgtaat tgaaactatt gaaatcgagg actaagatga
    12181 aaatcggtga taagctaaag gggcgtatta cagggattca gccctacggt gcctttgttg
    12241 agttagagac gggtgatacg gggctgattc acatttcaga aattcggaca ggatttattg
    12301 aaaatattca tgaaaccttg aaagtcgatg aagaggttca agttcaggta gtggatttag
    12361 atgaatttac ggggaaagcc agtctttcta tccgcacttt ggaggaagaa aagtaccagt
    12421 ttcctagacg gagacgcttt tcaagcgacc gctttaacta cggttttgct ccctttcgac
    12481 gaatgctacc aatctggact ggagaagccc tgcaccattt aaaaaagaag aagtagttta
    12541 gagttttata ttttttgtaa tgttaatata aatttgctat aataggacca tggaagaaga
    12601 acaattatta aaatcaggag agcgcattaa ccagctcttt tcgacagata tcaaaatcat
    12661 tcaaaataga gaggttttta gctattcggt ggatagtgtt ctcttatcac gatttccacg
    12721 ttttcctaag aaggggttga ttgtggattt ctgtgctggg aatggagcag tggggctttt
    12781 tgctagcact cgtactcaag cacagatatt gtctgttgag attcaggagc gtttggcgga
    12841 tatggctgaa cgctctgtcc gtttgaatgg attagaggag caaatgcagg tcatctgcga
    12901 tgatttgaaa aatatgcctg ctcacattca ggggagtaag gtggatatga ttttgtgtaa
    12961 tccaccctat ttcaaggtgg atccttattc taatctgaac gagagtgaac attatctctt
    13021 ggctcgacac gaaatcacga ctaatttgga agaaatctgt catagtgccc agagtattct
    13081 caagtctaat gggcgtttgg ccatggttca tcgtcctgat cgacttctgg atattttgga
    13141 tacgttaaaa cgacataatc tagcccctaa gcgcctgcag tttgtttatc caaaaagaga
    13201 aaaggaagcc aatatgcttt tgattgaggc gatcaaggat ggctcaacaa gtggctttaa
    13261 ggtcttacct cctttgattg tccacaatga tgatggctct tatacgcccg aaatcgaaga
    13321 gatttattat ggatcataag gcttatatgt acgttctgga gtgtcgtgat ggatcctact
    13381 atataggcta tacgactgat atgagaagac gcctcgctat ccacaatagt gggaagggag
    13441 ccaaatatac acgagcacgc ttgccagtca aacttatcta tgctcaaggt tttgccagta
    13501 aggaagaagc catgtcggct gaagctcttt tcaagcgtaa gaagaggcca cagaaggaag
    13561 aatttttatc tgaaaatcaa gatagaaatt tactcagtta ttttgaagaa tcgtggggag
    13621 tcctttgact cctcttacct ttgtcaaaaa gcgaaaaaaa tgctacaata aagaaaataa
    13681 acaaaatgag gtattatcat gtccaagatt ctagtatttg gtcaccaaaa tccagactca
    13741 gatgccatcg ggtcatctgt agcttttgcc taccttgcaa aagaagctta cggtttggat
    13801 acggaagctg ttgcccttgg aactccaaat gaagaaacag cctttgtctt gaactatttt
    13861 ggtgtggaag caccacgtgt tatcacttct gccaaagcag agggggcaga gcaagttatc
    13921 ttgactgacc acaatgaatt ccaacaatct gtatcagata tcgctgaagt agaagtttac
    13981 ggtgttgtag accaccaccg tgtggctaac tttgaaactg caagcccact ttacatgcgt
    14041 ttggagccag ttggatcagc gtcttcaatc gtttaccgta tgttcaaaga acatggtgta
    14101 gctgtgccta aagagattgc aggtttgatg ctttcaggtt tgatttcaga tacccttctt
    14161 ttgaaatcac caacaacaca cccaacagat aaaatcattg ctcctgaatt ggctgaattg
    14221 gctggtgtaa acttggaaga atatggtttg gcaatgttga aagctggtac caacttggct
    14281 agcaaatctg ctgaagaatt gattgacatc gatgctaaga cttttgaact caacggaaat
    14341 aatgtccgtg ttgcccaagt gaacacagtt gacatcgctg aagttttgga acgccaagca
    14401 gaaattgaag ctgcaatgca agctgccaac gaatcaaacg gctactctga ctttgtcttg
    14461 atgattacag atatcgtcaa ctcaaactca gaaatattgg ctcttggtgc caatatggac
    14521 aaggtcgaag cggctttcaa tttcaaactt gaaaacaatc atgccttcct tgctggtgcc
    14581 gtttcacgta agaaacaagt ggtacctcaa ttaactgaaa gctttaatgc gtaagatttt
    14641 gggtgtcagc tcaaaatcgg aaagtctagt ttgccttata tcgaaaggag tttcggctcc
    14701 tttttttcta ggagtgaagt atgttagaaa atggcgattt gatttttgtg agagatgggt
    14761 cagacatggg acaggccatc cagacttcca caggtaacta tagccatgtt gccatttatt
    14821 tggatgggat gatttatcat gctagtggac aggctggtgc tgtctgtcaa gaaccggcag
    14881 acttctttga gtccaatcat ttgtacgacc tctatgttta cccagaaatg gatatccagt
    14941 cggtgaagga aagagcttgc agacatcttg gagcacccta caatgcttct ttctatccag
    15001 atgcagctgg tttctactgc tcccagtata tagcagaaat cctacctatt tttgaaacta
    15061 ttcctatgaa atttggagat ggggaacagg agattagtga tttttggagg gagtattaca
    15121 tagaactagg tctgcctgtt cctctgaacc aagctgggac caatcctagt cagttggcag
    15181 catcgcctct gttacaatgt aaagaaagga atcttcatga ttcagatttt taattcatct
    15241 cgtttgacga gacagccatt tttggagaat tgatccgcta tctggaccag tatgaggatg
    15301 tgattctacg ggaaattaag gctcaatttc cagatgttgc agttgataaa ctcatggaag
    15361 agtatataaa ggcaagcttg attctacgtg aaaataagcg ctattacctc aattttccta
    15421 cgcttgaatc acttgatagt cttgaactgg atcaagagat ttttgtcaga gaagctagtc
    15481 cggtctatca agccttgttg gagcagagtt ttgagacgga attgcgcaat caaatcaatg
    15541 cagctatttt agttgaaaga cggactttgc gcgcattaaa atgaccctgt ccaattattt
    15601 ttacaaggtc aaacagcagt atcctttgac agaaaaacag caggagctct atgacatttt
    15661 aggagatgtt aatcctgagt atgcactcaa gtatatgacg gcttttttgt tgaaatttct
    15721 caaaaaagac cagcttatgc agaaatgccg tgatatcttt gtggacagtt tggttgtctt
    15781 aggctatatt gtgcaaaatg aagatagaaa gtatgagttg gctatcgatt ttgataagga
    15841 gagattaact ttctacttag cgtgatttct tgtttctgag cacattgttt gactttcctt
    15901 agtattcggt ataaactata tgtaaccggt aacacatatc ggaataaact aaaggagaca
    15961 atcatatgtc acttgaaaac aaattggaac aagcaacagg cgctgtcaaa gaaggttttg
    16021 gtaaagttac tggagacagc aagacagaac ttgaaggagc tgttgaaaaa acagttgcta
    16081 aggcaaaaga cgttgtagaa gacgcaaaag gtgctgtaga aggtgccgtt gaaggtttga
    16141 aaaacgtttt tactaaataa taggaaaaaa tcaagggttt cattttccct tgattttttc
    16201 tattcttata aataattttc tgcgacggct gtatctcctg ggtaggattc tttcttgccc
    16261 tggatgattt ggtaacaatc ggctccctta cccgcaataa taactgcatc taattcgtga
    16321 tttgtgatag ccattgccgc cttgatggct tcttggcgat ccgcaatctt ttcaacagga
    16381 tgattgatgt agctactaat ttcatctgca atggccattg ggtcttcata gttagggtca
    16441 tcagcagtca gaaagacttg aatctcaggg tgttgattga ggaggaggcc aaagtcctta
    16501 cgacgacttt ctcccttgtt tcctgttgat cccagaacca gagcaatctt tccggtttga
    16561 tgagtttcaa ccacattgat gagttttttc agactatccc cattgtgggc atagtcgatg
    16621 aagaccttgg ctccattttt ctgagtgagg acttccatac gaccaggaac gcgggttgca
    16681 gcgatgcctt ttttgatgtc ctcaagactt gctccgagac ggagacaagc aagtccagca
    16741 gcaactgcat tttcttggtt gaagttgcca atgagttgga tatcataatc tccagcgagt
    16801 ttacccgtag ctgaaaagct aaaggctttg gaattctcga tttggttatc aaattggcta
    16861 ccatagaaat catggtcttg atcttcaacc tgttctttca agactgagaa gtggtccatg
    16921 tcactgttaa tgatgactgc tcggctattt tccatcaaga gacgcttgtg gtagaaatag
    16981 tcttcaaagc tagggtgttc aatcgggccg atatggtcag gagtgatgtt aagaaagact
    17041 cctacatcaa aggtcagtcc atagactcga tggactagat aggcttgact ggagacttcc
    17101 atgatgaggt gggtacggtc attttgcaca gcctgattca tcatgtcaaa gaggtcaata
    17161 ctctcagggg ttgtcaacgc tgacttaaag aaagtctcgc catcaagagt tgtgttcatg
    17221 gtcgacaaca tagcaggtct atgcccttga gataagatgt tataggcgaa ataggttgct
    17281 gttgtcttac ccttagtacc agtaaaggca aggagtttga gtttctcttg tggattacca
    17341 tagaactcca tggcaatcaa actcatggct ttctttatat cgttcacaat gatgacaggg
    17401 atatcgactt cgtagtcctt ttcagctaca taccaagcta aaccttgtgt tatagcagaa
    17461 agaaggtatt cttttttaaa ggcagcgcct tttgcaaaaa aaagagtgtc ttctgttact
    17521 tttcggctgt cgtagctgat gctatcaaaa ataactttgc tgtagttgta gtggtaatga
    17581 ccttggtcaa taatttcgcg aaaaaggcca tctttcttta aaatatctaa tacggtttca
    17641 atcttaatca tactttctat tgtaaaccga aagtcgtaaa tttacaagta acaaggaaaa
    17701 gtttataatg gaagataagg agtttttcct agttatcaaa attgaatgag gaatctatgt
    17761 cgcacgaaaa caatcaccag caggcccaga tgttacgggg gactgcttgg ctaacggcta
    17821 gtaactttat cagtcgccta ctcggggctg tttacattat cccttggtac atctggatgg
    17881 gggcttatgc agctaaggca aatggtctct ttaccatggg ttacaatatc tatgcttggt
    17941 tcttgttggt ttcaacagcg gggattccag ttgcggtggc caagcaagtt gccaagtata
    18001 ataccatgcg agaagaagag catagctttg ccctgattcg gagcttctta ggctttatga
    18061 caggactagg cctggttttt gctttagtct tgtatgtctt tgctccttgg ctagcagact
    18121 tgtctggcgt gggcaaagac ttgatcccaa tcatgcaaag cttggcttgg ggagtcttga
    18181 ttttcccgtc tatgagtgtt atccgaggat ttttccaagg gatgaataac ctcaaaccct
    18241 atgccatgag ccaaattgct gagcaggtca ttcgtgttat ctggatgctc ctagcaacct
    18301 ttatcattat gaagctcggt tcaggagatt atctagcagc cgttacccaa tcaacctttg
    18361 ctgcctttgt cggtatggta gccagttttg cagtcttgat ttatttcctt gcccaagaag
    18421 gttcactcaa aagagtcttt gaaacaggag ataagattaa cagtaagcgt ctcttggttg
    18481 ataccattaa ggaagccatt ccttttatcc tgacagggtc tgccatccag ctcttccaga
    18541 ttttggatca gctgaccttt atcaatagta tgagctggtt taccaactac agcaatgagg
    18601 acttggttgt catgttttct tatttctcag ccaatcctaa taaaatcacg atgattttga
    18661 tttctgtagg ggtttcgatt gggagtgttg gtttgccact tttgacggaa aactatgtca
    18721 agggggactt gaaagcagct tctcgtctcg ttcaggacag tctcacccta ctctttatgt
    18781 tcttgctacc agcaacggtt ggagtggtta tggtaggaga acctctttat acggtcttct
    18841 atggtaagcc agatagtttg gctctgggct tatttgtctt tgcagttttg cagtctatta
    18901 ttttaggctt gtacatggtc ttgtctccaa tgcttcaggc catgttccgc aaccgcaagg
    18961 ccgttctcta ttttatctat ggttctattg ccaagctagt cttgcaacta cctaccatcg
    19021 ccctcttcca cagttatggt cctttgattt caacaaccat tgctctcatc attcctaacg
    19081 tcttgatgta tcgggatatt tgtaaagtaa ctggtgtcaa gcgcaaggtg attttgaagc
    19141 gaaccatttt aatcagtttg ctgaccctag tcatgtttct gttaatagga accatccagt
    19201 ggctgttagg atttttcttc caaccaagtg gacgtttgtg gagcttcttt tatgtagctc
    19261 ttgtcggtgc catggggggt ggactttata tggttatgag tctgcgtacc tatttattag
    19321 ataaggtaat aggaaaagcc caagcagatc gcctgcgagc aaaatttaag ctttcgtaag
    19381 gtagcattta taaataaaag gaataagttg aacaatcttt taggagaact tgaagcttat
    19441 tcctttttta gcgtaaaaat agctaaaatt atatttcaaa aatagaaaat gaggcttttt
    19501 tcgatttttt ggaaaaaatc attgactaaa caaactaaac gttgtataat aaaacaaata
    19561 tttaaagcag gaggttccgg aaatgaaaaa gtctaagagc aaatatctaa ccttggcagg
    19621 tcttgtcctg ggtacaggag ttttattgag cgcgtgtgga aattctagca cggcgtcaaa
    19681 aacatacaac tatgtttatt caagtgatcc atctagcttg aactatctag cagaaaaccg
    19741 cgcagcaaca tccgatattg ttgcaaattt ggtagacggg ttattagaaa atgaccaata
    19801 tgggaatatt attccatcat tagcagagga ttggactgtt tctcaggacg gtttgaccta
    19861 tacctacaaa cttcgtaagg atgccaagtg gtttacttct gagggagaag aatatgcgcc
    19921 tgtaactgcc caggattttg tgacaggttt gcaatatgca gctgataaaa aatcagaagc
    19981 cttgtatcta gtgcaggact ctgttgctgg tttggatgac tatatcactg gtaaaacaag
    20041 cgacttttca actgtcggtg tcaaggcact tgatgaccaa acggttcaat atactttggt
    20101 taaaccagaa ctttactgga attcaaaaac acttgcaacg atactttttc ctgttaatgc
    20161 agatttcctg aaatcaaaag gggatgattt tgggaaggcg gatccatcta gtattttgta
    20221 caatggacct ttcttgatga aagcacttgt ctcaaaatct gctattgaat ataagaaaaa
    20281 ccctaattac tgggatgcta agaatgtctt tgtagacgat gtgaaattga cctactatga
    20341 tggtagcgac caagaatcac tggaacgtaa ttttacagct ggtgcttata ctacggctcg
    20401 tctttttcct aacagctcca gctatgaagg gattaaagaa aaatacaaaa acaatatcat
    20461 ctatagtatg caaaattcaa cttcatattt ctttaatttt aacctagata ggaagtctta
    20521 caattatact tctaaaacaa gtgacattga aaagaaatcg actcaggaag cagttctcaa
    20581 taaaaacttc cgtcaggcta tcaattttgc ttttgacaga acatcttatg gggctcagtc
    20641 tgaagggaaa gaaggtgcaa caaagatttt gcgtaaccta gtggttcctc caaactttgt
    20701 cagtatcaag ggaaaagact ttggtgaagt tgtagcctct aagatggtca actatggtaa
    20761 ggaatggcaa ggtatcaact ttgcggatgg tcaagaccct tactacaatc ctgagaaagc
    20821 caaggctaag tttgcggaag ctaagaaaga actcgaagca aagggtgttc aattcccaat
    20881 ccacttggat aagactgtgg aagtaacaga taaagtaggc atacaaggag ttagttctat
    20941 caaacaatca attgaatctg ttttaggttc tgataatgta gtgattgaca ttcagcaatt
    21001 aacatcagat gagtttgaca gttcaggcta ctttgctcaa acagctgctc agaaagacta
    21061 tgatttatat catggcggtt ggggacctga ttatcaagac ccgtcaacct atctcgatat
    21121 ttttaatact aatagtggag gatttctgca aaatcttgga ctagagcctg gtgaggccaa
    21181 tgacaaggct aaggcagttg gactggatgt ctatactcaa atgttggaag aagctaataa
    21241 agagcaagat ccagccaaac gttatgagaa atatgctgat attcaagctt ggttgattga
    21301 tagttcttta gttcttccaa gtgtttcgcg tgggggaaca ccatcattga gaagaaccgt
    21361 accatttgct actgcctatg gtttaaccgg tacaaaaggg gttgaatcat ataaatacct
    21421 caaagtacaa gataagattg tcacaacaga cgaatatgca aaagccagag aaaaatggtt
    21481 gaaagaaaaa gaagaatcca ataaaaaagc ccaagaagaa ttggcaaaac atgtcaaata
    21541 aaatctaatt gtagataagt ttgtgtaaga agtctttgtg cttaaaaacg cataatatca
    21601 ggtatataaa atcctagatg ttatgcgttt tgttatagga agatttatta gattttatcc
    21661 tcaaattgag ttattcccga ctttatccgt tgaaatatta taaggagtat ttatgaaatt
    21721 aaaattatta agagtagata ctaaggtgat tatggggagt ttcttacttg ttctgtctag
    21781 tctacttgct ttgttgcttc cccttatctt aaagggttta atagatggga gttctattga
    21841 aaatataggt tccaaagtat ttcaatcgtt tttgattttt attggtcaag ccttgttttc
    21901 ttctattggt tactatctgt ttagtcaatc gggtgaaaaa aagatagcaa aaatcaggaa
    21961 aaaagtgata gaggggttga tttatgcaga gaaatccttc tttgataaga gccaaagtgg
    22021 ggagttgact tctgccattg tcaatgacac gagtgtcatt cgtgagtttt taattacgac
    22081 tttcccaaat attattctga gtttagttat ggtacttggt tccattgtag tcttatttag
    22141 tcttgattgg aatctttctc tacttttatt catcactctt ccttgtatga tgtttattat
    22201 cttgctcctt tccaatatca gtgaaaagta tagtcgtcgt ttacaggagg aaatcggatt
    22261 tttaacaggg caattgactg aaaagattca agaacatgaa ttaattaaga ctaaccaagc
    22321 agagaaaagt gtacaggatg ttttggataa ttgtattgaa agggtacaaa acaattcact
    22381 gaaatcagat agggttactt cttttgagac cccgtttgct ctcttattta tctttgcgac
    22441 tatagctgtg atgctaacct atgggggtta tcgggtcagc gcaggatata tatctgtggg
    22501 aaccttggtt tcgtttttga tttacctctt tcaattactt aatcctatta gtaatatagc
    22561 taattttgta actgtttatt ctaggagcaa gggatcttca gttgcactgg agaacttgct
    22621 tgcagttcct aaagaaaaat ttgagtgagg aaaatcggta tcaggacaag ggttgaattt
    22681 taaccatgtc tattttggtt atgatgaaaa tcgacctgtc ttaaaggata ttacttgttc
    22741 aattttcaag gggcaaaaaa ttgcttttgt tggaccatct ggatcaggaa aatcaacgat
    22801 tgtgcgtttg ttagagcggt tttataaacc gctttcagga gatattctaa tggagcaatc
    22861 aagtatatat gattttaact taaaagaatg gagaagtaaa atcgcttagt aactgatgat
    22921 gaattgatga aagtgctaga cttagtatca ctaggtgatg agattcgctc catgaaagag
    22981 ggactagata ctgaagttgg tgaacgcgga cgactcttgt caggggggca aagccaaaga
    23041 cttcaaatag ctagagccta cttaaaagat gctgaaattc ttatatttga tgaagccact
    23101 gctaatcttg atgcggattc tgagtatgcg attatcagta gcctctattc tgtattaaag
    23161 gagaagacgg ttgtgattat agcgcatcgt ttgtcaacgg taaaagatgt ggattgtatt
    23221 ttcttcttag aggaggggaa aatcactggc tcaggaactc ataaggaact actggaaaat
    23281 catgagcgtt atgctcgttt tgtgcaggag caaatgatag agtgaaggtg tcttttgaga
    23341 ttcaccattt tatagtctat taaagggagc aggaaaaact ccctttttat atagtttgaa
    23401 actataacta gctcttgaaa agaagaaaat gagttgatga aaataagtgg tacaatagtt
    23461 actatagatt tggaggtatt gtatgagcaa ggaattacac attaacacaa ttttggccca
    23521 ggcgggtatt aagtcagatg aagcgacagg tgcattggtg acaccgcttc atttttcaac
    23581 gacctatcag catccagagt ttggtcgatc tactgggttt gactatacgc gcactaaaaa
    23641 tccaactcgt agtaaggctg aggaagtctt ggcggctatt gagtcagcag actatgccct
    23701 agcgactagc tcagggatgt cagctattgt actggccttt agcgtctttc cagtaggaag
    23761 taaggtcttg gcagtgcgtg atctttacgg tggttctttt cgctggttta accaagtgga
    23821 gcaggaaggt cgtttccatt ttacctatgc caatacagaa gaagagttga ttgccgagtt
    23881 agaaaaggat gtggatgttc tctatatcga aaccccaacc aatcccttga tgttggaatt
    23941 tgatatcgaa aaactagcaa aattggctca tgctaagggt gccaaagtgg tggtggacaa
    24001 taccttctat agccctatct accaacgtcc gattgaagat ggagcagata tcgttctcca
    24061 ttcagcaacc aagtatctag caggccacaa tgatgtcttg gctggagtgg ttgtgaccaa
    24121 tagtttagaa ctatacgaga agctttttta caatctcaat acaacagggg cagtcttgtc
    24181 tccatttgac agctaccagt tgcttcgtgg tctcaagacc ttatctcttc gtatggagcg
    24241 ctcaacagct aacgcccaag aagtggttgc ctttttgaag gattctccag cagttaagga
    24301 agttctctac actggtcgtg gaggcatgat ttcctttaaa gtagccgatg aaacacgcat
    24361 tcctcatatt ttgaacagtc tcaaggtctt ctcttttgcg gaaagtttgg gcggagtgga
    24421 aagtcttatt acttatccaa cgactcaaac tcatgctgat attccagcag aagtacgcca
    24481 ttcttatggt ttgacagatg acctcttgcg tttgtctatt gggattgagg atgctagaga
    24541 tttgattgca gatttgcgcc aagccttaga aggataagac aaagatggga aaatatgatt
    24601 ttacaagcct gcccaaccgt ttagggcacc atacctataa atggaaagaa acagaaacgg
    24661 atagtgaagt tctaccagct tggatagcgg atatggactt tgtggtcttg cctgaaatcc
    24721 gccaagccgt gcaaacttac gcagaccaac tggtttatgg ttatacctat gccagtgaag
    24781 acttaattaa ggaaattcaa aagtgggaag ctacacaata cggttacaac tttgacaaag
    24841 aggctcttgt ctttatcgag ggtgtggtac cagccatctc aacagctatt caaaccttta
    24901 caaaagaagg cgaggcggtt ttaattaaca cgcctgtcta cccacccttt gctcgcagtg
    24961 tcaagttgaa taatcgtaga ttgattacta attccttagt ggaaaaggat ggtctgtttg
    25021 agattgactt tgaccaactt gaaaaggatt tggtggaaga ggaggttaaa ctctatattc
    25081 tttgcaaccc tcacaatcct ggtggacgtg tttgggaaaa agaagtgttg gagaagattg
    25141 gccaactttg ccaaaaacac ggtgttttgt tagtttcgga tgagattcac caagatttga
    25201 ccctctttgg tcacaaacac cagtctttca ataccatcaa tcctgccttc aaaaattttg
    25261 ctatcgtctt gagcagtgcc actaaaacat ttaatattgc tggaacaaaa aattcctatg
    25321 cagtcattga aaatcctaag ttgagactgg ctttccagaa acgcctgttg gccaataatc
    25381 agcatgaaat ttcaggcttg ggttatttgg cgacagaagc tgcctatcga tacggtaaag
    25441 attggctaga ggaactcaag caagtctttg aagaccacat caattatgtg gtggatctat
    25501 ttggaaaaga gactaaaatc aaggtcatga aaccgcaagg tacctacttg atttggcttg
    25561 acttttcagc ctatgacctg actgatgaaa cattgcaaga gttgttgaga aatgaagcca
    25621 aggttatcct caaccgtggt ttggattttg gagaggaagg aagtctccat gcccgcatca
    25681 atatagctat gcccaaatct ctgttgcaag aagtctgtca gcggattgtg gctacttttg
    25741 ccaaacgtta aaaatccagc cttctaggag aaaagtcttc ctagaaggct attttcatag
    25801 gcgaaaatat ggtataataa aaagataagg taaaggtgaa aatatggcta aattgattcc
    25861 ggggaaaatt cgtatcgaag gtgttgccct ttatgaaact ggtaaggttg atatcatcaa
    25921 ggaaaagaac aatcggctct acgctcgcgt tgcagaagaa gaactgcgct atagtttaga
    25981 ggatgatttg gttttttgtg cctgtgattc ttttcaaaag aggggctact gtgtgcattt
    26041 ggcagcgcta gagcattttc tgaaaaatga tgagcgtggt caggaaatct tgtggagtct
    26101 ggaagaaggt catgaagaaa aagaggccgt tgaaaccaag gtgaccttgg gtggcaagtt
    26161 tttgaatcga attttatctc caaaatcaga atgcgcctat gagttatcag ctgtgggtca
    26221 ggtggaagca ggaaccaatc atatcttgtg gactctgaga atcggccaaa tcaatagcca
    26281 aaaatactat gtcattcggg atattccact ttttttaagg attgtcgagc agagaaagtc
    26341 gtatatgatt ggcaagattt atgaggagtc tctttcttgg gaagcctttg atgatgccag
    26401 ccaagaactt ttgactttct tgcacggact aacggaggaa gggctggttc cagacctctt
    26461 tttccaaaac caaggtcggc acctcttttt ccctctgacc ttttttgagc agggtgtgaa
    26521 tttactgatg gccttgcccc attttcaatt tgaccatcaa gtggatagct accaaaccct
    26581 gctttttcag gatatgcatg ctgatgccaa tctatttgcc tttacagtaa cagaatactc
    26641 ggactatttt gaaatggaaa tcagtgagag tcctagggtc aatgtctttt atcagggagc
    26701 agtacttttc cataaaggtc aggtttattt tttaacagac cagcagatgc gtcttctcaa
    26761 ggaaattaaa gcgttacctg tgggtcaaca aggaaagaaa tacctgcaat ttgatagcag
    26821 tgatcgagac aaattggcct cctgtctgac tctttttatc cagatgggca ccgtttcagc
    26881 tccagaacgt ctacaaatca aaacttttgc gccctctttt tactttgaca gggaagaaga
    26941 taatcggatt cgtttagaaa ttcagtttga ttatggaaat agacaggtat ctagccgaca
    27001 agagctagaa gaattaccat tttcaagtga cgcggactta gaagaaagaa ttttccaagt
    27061 ctgtttggct gcgggctttg aagccgattt tcaatcttgg cgtcaggcct taaaagcgga
    27121 gtctgtctat catttttttc atgatatcat tccagtcttt gaaaaactcg ggcatgttga
    27181 cctatcagat aaactagaag agctttatag cctagcgagt cctcaggtgc agattgcctc
    27241 caagggaggt ctcttggaaa tccagtttga ttttcaaaat attgcccagg aggaaatcga
    27301 ccaagccatg caggccttgg ttgccaatca ggatttttat attgattcgt ctaatcaagt
    27361 ttactttttc gatgaagaaa ccaagaaaat tcgccaaaat ctacaggaac tggggcaatt
    27421 tgaattaaaa gatgggacct tgcaggctcg gaaatccttg gcctacagtt tagctcatct
    27481 ctttgaaggg cgagaccgtg tttctttttc acaagaattc cagaatctgg cccaggattt
    27541 gacgcatcca gaggactttc ctttgcaagc aactcaggtc aaggctgact tgcgagatta
    27601 tcaggaaaag ggaattggct ggttgcagat gctccatcat tatggttttg gtgggatttt
    27661 ggctgatgat atgggacttg ggaaaaccct tcagaccatt gcttttttga ctagtcaagt
    27721 gacaaaagaa agtcgagtct tgattctcgc tccgtcgggt ttgatttaca actgggcgga
    27781 tgagtttcag aaatttgccc cacagttgga tgtggctgtt gttcatggtt tgaaagcaag
    27841 tcgtgaggag attcttgccg agagccatca aatctatgtg actagctatg ccaccttccg
    27901 tcaggacagt gagttttatc aggggatggc ctttgacttc cttttcttag atgaggctca
    27961 ggtcatgaaa aatgcccaga ccaagattgc ccagaccttg agacaatttg tggtgccgtc
    28021 ggtctttgcc ttgtcaggaa ctccgattga aaaccatctg ggtgagttgt ggtctatttt
    28081 ccaaatcgtc atgcccggac ttttgccaag caagaaagaa tttatgaaat tgccagcaga
    28141 gcgagtggct cagtttatca agcctttcgt gatgcgacgc aagaaagaag aagttctgac
    28201 tgaattgcca gacttgattg aggtggttta taaaaatgaa ctggaagacc agcaaaaggc
    28261 tatttacctt gcccagttac aacagatgcg agaccatctg gctcaagtgt cagaacagga
    28321 atttcagcga agtcgtgtgg aaattttatc tggtttgatg cgcttgcgtc aaatatgtga
    28381 cactcctgcc ctgtttatgg aagattatca gggagccagc ggcaaactag atagtctccg
    28441 agacctactg gtacaggtgg cagacggcgg acaccgtgtc ttgattttct ctcagttcaa
    28501 gggaatgttg gaaaaaattg aacaagaact gccagacttg ggcctgactt cctttaaaat
    28561 tacgggttca accccagcca aggaaagaca agacatgacc aaggccttta atcaaggaga
    28621 aagagatgcc tttctgattt ccctcaaggc tggtggggtc ggtctgaacc tgacaggtgc
    28681 agatacagtg atcttggttg acctttggtg gaatcctgcg gtggaagcgc aagccattgg
    28741 ccgtgcccat cggatgggtc aggaagaaac ggttgaggtc tatcgcttgg tgaccaaggg
    28801 aaccattgaa gaaaaaattc aggaactcca agaacaaaag aaacatctgg tgtcacaagt
    28861 attggacggc acagagtcac gtggtagtct gaccctagca gaaattagag aaattttggg
    28921 aatttctgaa gccagcactt gaaaaatcaa gacaatacgc tataatgaag tgttgaaagg
    28981 aaatagaaaa tgaaacaaga acgatttcca ttggtgtcag atgacgaggt catgttgact
    29041 gaaatgccag tcatgaatct ctatgatgag tctgatctga tcagtaatat caagggtgag
    29101 tatcgagata aaaattattt agaatgggct cctattgctg aagaaaaacc agtaaaaccg
    29161 attgaaaagc aagtagggaa acctaaaaaa gctcctttag gggttaaaaa agaaggaaag
    29221 agctatgcgg aggtggcgcg tgaagaagcg cgtgcagact tgaaaaagaa acgctctgct
    29281 aactatctaa ctcaggattt cagccttgcg agacgtcatt ctcagcccag tctagttaga
    29341 cagggcaatc aaccgacaac tcctttccaa aaggaaaatc ctggtgaatt tgtcaaatat
    29401 agccaaaaat tgacccagtc tcattatatc ttggcggaag aagttcattc tatccctacc
    29461 aagaatgaag aagtgtcagc acctgctcca aagaaaaaca attatgattt tctaaagaag
    29521 agccaaatct acaataaaaa aagtaaacaa acagaacaag aacgtcgggt tgcccaagag
    29581 ttgaatctga ccagaatgac agaataggga gaaaacatgt caaagacata tcattttatc
    29641 ggaattaagg gatcagggat gagtgccttg gccttgatgt tgcaccagat ggggcacaag
    29701 gttcagggat cagatgttga aaagtactac tttacccaac gcggtcttga gcaggcagga
    29761 attaccattc ttccttttga tgaaaagaat ctagacggtg atatggaaat tatcgctgga
    29821 aatgcctttc gtccagataa caacgtcgaa attgcctatg cggaccaaaa tggtatcagc
    29881 tacaaacgtt accatgagtt tctaggtagc tttatgcgtg actttgttag catgggagta
    29941 gcaggagcac atggaaaaac ttcaacgaca ggtatgttgt ctcatgtctt gtctcacatt
    30001 acagatacca gcttcttgat tggagatggg acaggtcgtg gttcggccaa tgccaaatat
    30061 tttgtctttg aatctgacga atatgagcgt cacttcatgc cttaccaccc agaatactct
    30121 attatcacca acattgactt tgaccatcca gattatttca caagtctcga ggatgttttc
    30181 aatgccttta acgactatgc caaacaaatc accaagggtc tttttgtcta tggtgaagat
    30241 gctgaattgc gtaagattac gtctgatgca ccaatttatt attatggttt tgaagctgaa
    30301 ggcaatgact ttgtagctag tgatcttctt cgttcaacaa ctggttcaac cttcaccgtt
    30361 catttccgtg gacaaaactt ggggcaattc cacattccaa cctttggtcg tcacaatatc
    30421 atgaatgcga cagccgttat tggtcttctt tacacagcag gatttgattt gaacttggtg
    30481 cgtgagcact tgaaaacatt ttccggtgtt aaacgtcgtt tcactgagaa aattgtcaat
    30541 gatacagtga ttatcgatga ctttgcccat catccaacag aaattattgc gaccttggat
    30601 gcggctcgtc agaaataccc aagcaaggaa attgtagcag tctttcaacc gcataccttt
    30661 acaagaacca ttgccttgtt ggacgacttt gcccatgctt taaaccaagc agatgctgtt
    30721 tatctagcgc aaatttatgg ctcggctcgt gaagtagatc atggtgacgt taaggtagaa
    30781 gacctagcca acaaaatcaa caaaaaacac caagtgatta ctgttgaaaa tgtttctccg
    30841 ctcctagacc atgacaatgc tgtttacgtc tttatgggag caggagacat ccaaacctat
    30901 gaatactcat ttgagcgtct cttgtctaac ttgacaagca atgttcaata ggatgttccc
    30961 atggaaattc caattaagat cattcaggca agcaagtctg atttgcctga gataggggca
    31021 cttcagacct cgtcttttcc agctgaaaag cagcaacttt cccatatttt agaagaaagt
    31081 atccgtaagt gtgcggatac ctttcttcta gctagggatg aaaatcaact tttaggctat
    31141 attttatcaa gtccccagtc agacaatccg caatatctaa aagtacattc tttagtcatc
    31201 gagtctgacc atcagagaca gggcttggga acacttcttc ttgcagcctt gaaagaggtg
    31261 gcagttgatc tggattacaa agggattcgt ttggagagtc ctgatgagct gctttcctat
    31321 tttgaaatga acggttttgt tgatgaagaa gcaactttgc tctatgcaac tagccagggc
    31381 tatagtatga tttggtttaa tcccttttat ctggaggaac aatgaaaatc agacaagcaa
    31441 gattagaaga tttggatcgg attgttgaac ttgaatttga aaatttttcg gtcgaagaag
    31501 ccattcctcc ttctgtcttt gaagcacatt tgagagaaat tcagacctct tttctggttg
    31561 ctgaaaaaga aggaagaatc atgggttata tcgaaggacc agttggcctg caccgccatc
    31621 tgcaagacca gtcttttaca gaagaaataa aagactatag tcatgagcct ggtggttata
    31681 tctctgtgac ctgtctgtct attgccaagg aggcacaggg actcggactg ggtcagaaat
    31741 tgctgacagc tttgaaagaa gttgctcttg aagatgagag agatggcatt aatctaacct
    31801 gtcatgacta tctcatcgcc tattatgaaa aacatggatt tgtcaacgaa ggccagtccc
    31861 agtcaacctt tgcaggggaa acatggtatg atatggtctg ggaaatgaaa aaataagtta
    31921 ggaaaagtat catagattgc tttttttgga cttttaagat ataatattat ggattatcaa
    31981 caaggaggaa aaacttttga gtgaaaagtc aagagaagaa gagaaattaa gctttaaaga
    32041 gcagattctg agagatttag aaaaagtaaa aggctatgat gaagttctga aagaagatga
    32101 ggcagtagtt cgcactcctg caaatgaacc ttcagctgaa gaactcatga ctgattcctt
    32161 gtcaacggta gaggagatta tgagaaaagc tcctaccgtg cctactcacc caagtcaagg
    32221 tgtaccagct tctccagcag atgagattca aagagaaact cctggtgttc caagtcatcc
    32281 aagtcaagat gtaccttctt ctccagcgga agaaagtgga tcaagaccag gtcctgttag
    32341 acctaagaaa cttgaaagag aatacaatga aaccccaaca agggtagctg tttcctatac
    32401 gacggcagag aaaaaagcag aacaagcagg tccagaaaca cctacgcctg ctacagaaac
    32461 agtggatatc atcagcgata catcacgtcg tagccgtaga gaaggagcaa aacccgttaa
    32521 tcctaagaaa gagaagaagt cacatgtgaa agcttttgtg atttcattcc ttgtattcct
    32581 tgccttgctc tcagcaggtg gttactttgg ttaccagtac gtgctagatt ctttgttacc
    32641 tatcgatgct aattctaaga aatatgtgac ggttggaatt ccagaaggtt caaacgttca
    32701 agaaatcggt acgacgcttg aaaaagctgg tttggtaaag catggtctga tttttagttt
    32761 ttatgccaag tataaaaatt ataccgactt gaaagcaggt tactacaatt tgcaaaagag
    32821 tatgagtaca gaagacttac tcaaagagtt gcaaaaaggt ggaacagatg aaccgcaaga
    32881 acctgtactt gcgactttga caattccaga aggttatacc ttggatcaga ttgctcaagc
    32941 tgtgggtcaa ttgcaaggtg acttcaaaga gtctttgaca gcggaggctt tcttggctaa
    33001 agttcaagat gagacgttta tcagtcaagc agtagcgaaa tatcctactt tactggaaag
    33061 tttgcctgta aaagacagcg gtgcgcgtta tcgtttggaa ggataccttt tcccagctac
    33121 atactctatc aaggaaagca caactattga gagcttgatt gatgagatgt tagctgctat
    33181 ggataagaac ctatctcctt actatagtac tatcaaatct aaaaatttga ctgtcaatga
    33241 gttgttgacc attgcttcct tggtcgaaaa agaaggtgcc aagacagaag atcgtaagct
    33301 cattgcaggt gtattctaca atcgtttaaa tcgtgatatg ccacttcaaa gtaatattgc
    33361 aatcttgtat gcccaaggaa aactggggca aaatatcagt ctagctgagg atgttgcgat
    33421 tgataccaac attgattcac cttataatgt ttataaaaat gtaggtctca tgcctggtcc
    33481 agtcgatagt ccaagtctgg atgcgattga gtcaagcatc aatcaaacta agagcgataa
    33541 cctctacttt gtagcagatg tcacagaagg caaggtctac tatgctaaca atcaagaaga
    33601 ccacgaccgc aatgtcgctg aacatgtcaa cagcaaatta aactaaacaa actaaaatta
    33661 tgtgatacgt cacataattt tctttagaaa atattatcag aagaaagttg agaaaaatgg
    33721 cagaaaaaac atatcctatg acccttgagg aaaaggaaaa acttgaaaaa gaattagaag
    33781 aattgaaatt ggttcgtcga ccagaagtgg tagaacgcat taagattgcc cgttcatacg
    33841 gtgacctttc agaaaacagt gagtacgaag cagctaagga tgaacaagcc tttgtcgaag
    33901 gacaaatctc tagcttagaa acaaaaatcc gctatgctga aatcgtcaat agcgacgcag
    33961 ttgcccagga cgaagtagcg attggtaaaa cagtcaccat ccaagaaatt ggtgaggacg
    34021 aagaagaagt ttatattatc gtaggttcag ctggtgcgga tgcctttgca ggtaaggttt
    34081 caaatgaaag cccaattggg caggccttga ttggcaagaa aacaggtgac acagcaacca
    34141 ttgaaacgcc tgttggtagc tatgatgtaa aaatcttgaa ggttgaaaaa acagcctaaa
    34201 aacagaaaaa ggagtgggga ggcgatgtgc ttcactcact cctttttcca ttttgctatt
    34261 cttcgaaaat ctcttcaaac cacgtcagcg tcgccttgcc gtatgtatgg ttactgactt
    34321 tgtcagtttc atctacaacc tcaaaac
//
LOCUS       DAVBCA010000018        33324 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.018, whole genome shotgun sequence.
ACCESSION   DAVBCA010000018 DAVBCA010000000
VERSION     DAVBCA010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33324)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33324)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33324
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.018"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..327
                     /locus_tag="VQU19_000809"
     CDS             <1..327
                     /locus_tag="VQU19_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HET2480081.1"
                     /translation="KPQTEKPEEETPREEKPQSEKPESPKPTEEPEEESPEESEEPQV
                     ETEKVEEKMREAEDLLGKIQDPIIKSNAKETLTGLKNNLLFGTQDNNTIMAEAEKLLA
                     LLKESK"
     gene            749..979
                     /locus_tag="VQU19_000810"
     CDS             749..979
                     /locus_tag="VQU19_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HET2480082.1"
                     /translation="MESIGIGLVIVSHSKHIAEGVVELISKVAKDVPITYVGGTEGGG
                     IGTSFDQVDRVVSENPADTLLAFFDLGSAIKC"
     gene            1383..2096
                     /locus_tag="VQU19_000811"
     CDS             1383..2096
                     /locus_tag="VQU19_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HET2480083.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFAHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYNLYAATNGITAIQTGRLAQSGLAPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            2154..2756
                     /locus_tag="VQU19_000812"
     CDS             2154..2756
                     /locus_tag="VQU19_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480084.1"
                     /translation="MSEVDFNEAVNYEFTSDTCQLANSIYQSLFKFFDKKNFSGDLIF
                     TWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLNMNRNGCMGDFPHDFF
                     DIYLDHVAKYAYEQKVNNIKEYYPLKRAILHQENALYFRFFSNFDDFLEKNYLKTIWQ
                     VSKETPFSEMDFNMFKNISEKIIFERGSKMLNDLKSNYKK"
     gene            2892..3545
                     /locus_tag="VQU19_000813"
     CDS             2892..3545
                     /locus_tag="VQU19_000813"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HET2480085.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            3555..4019
                     /locus_tag="VQU19_000814"
     CDS             3555..4019
                     /locus_tag="VQU19_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HET2480086.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            4032..5300
                     /locus_tag="VQU19_000815"
     CDS             4032..5300
                     /locus_tag="VQU19_000815"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HET2480087.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLG
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            5314..5574
                     /locus_tag="VQU19_000816"
     CDS             5314..5574
                     /locus_tag="VQU19_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480088.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            5585..6946
                     /gene="pdrM"
                     /locus_tag="VQU19_000817"
     CDS             5585..6946
                     /gene="pdrM"
                     /locus_tag="VQU19_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HET2480089.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDKIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTARFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            7100..8068
                     /locus_tag="VQU19_000818"
     CDS             7100..8068
                     /locus_tag="VQU19_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HET2480090.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            8084..9076
                     /locus_tag="VQU19_000819"
     CDS             8084..9076
                     /locus_tag="VQU19_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HET2480091.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDKNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYISEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKE"
     gene            9294..10337
                     /locus_tag="VQU19_000820"
     CDS             9294..10337
                     /locus_tag="VQU19_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HET2480092.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            10401..12086
                     /gene="lpdA"
                     /locus_tag="VQU19_000821"
     CDS             10401..12086
                     /gene="lpdA"
                     /locus_tag="VQU19_000821"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HET2480093.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EEDGYLIAILKGDGETVPVTEIIGYLGEERENIPTAGAASPEASPVPVASTSNDDGKS
                     DDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTYLHNAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMQSPLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDAEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEIIGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            12150..13139
                     /locus_tag="VQU19_000822"
     CDS             12150..13139
                     /locus_tag="VQU19_000822"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HET2480094.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINHIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(13206..14276)
                     /gene="xerS"
                     /locus_tag="VQU19_000823"
     CDS             complement(13206..14276)
                     /gene="xerS"
                     /locus_tag="VQU19_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HET2480095.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDSL"
     gene            complement(14860..16410)
                     /locus_tag="VQU19_000824"
     CDS             complement(14860..16410)
                     /locus_tag="VQU19_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HET2480096.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFIIIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGSLVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            complement(16426..17205)
                     /locus_tag="VQU19_000825"
     CDS             complement(16426..17205)
                     /locus_tag="VQU19_000825"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HET2480097.1"
                     /translation="MATIKEIKELLVTVKELESPIFLDLEKDNRSGVQKEISKHKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQVVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            complement(17192..18043)
                     /gene="ylqF"
                     /locus_tag="VQU19_000826"
     CDS             complement(17192..18043)
                     /gene="ylqF"
                     /locus_tag="VQU19_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HET2480098.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EGLDGND"
     gene            complement(18250..18426)
                     /locus_tag="VQU19_000827"
     CDS             complement(18250..18426)
                     /locus_tag="VQU19_000827"
                     /inference="COORDINATES: protein motif:HMM:NF012948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET2480099.1"
                     /translation="MQAGIPTDNEVSYALIYQQETLPATGSSTSALTALGLLAVGSLV
                     LLVHNMTGTVFCSL"
     gene            complement(18478..24369)
                     /gene="iga"
                     /locus_tag="VQU19_000828"
     CDS             complement(18478..24369)
                     /gene="iga"
                     /locus_tag="VQU19_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunoglobulin A1 protease"
                     /protein_id="HET2480100.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGMGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYREETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPSPRIVEKGTK
                     KTQVIKEQPETGVEHKDVQSGSIVEPAIQPELPEAVVSDKGEPEVQPTLPEAVVTDKG
                     ETEVQPESPDTVVSDKGEPEQVAPLPEYKGNIEQVKPETPVEKTKEQGPEKTEEVPVK
                     PTEETPVNPNEGTTEGTSIQEAENPVQPAEESTTNSEKVSPDTSSENTGEVSSNPSDS
                     TTSVGESNKPEHNDSKNENSEKTVEEVPVNPNEGTVEGTSNQETEKPVQPAEETQTNS
                     GKIANENTGEVSNKPSDSKPPVEESNQPEKNGTATKPENSGNTTSENGQTEPEKKLEL
                     RNVSDIELYSQTNGTYRQHVSLDGIPENTDTYFVKVKSSAFKDVYIPVASITEEKRNG
                     QSVYKITAKAEKLQQELENKYVDNFTFYLDKKAKEENTNFTSFSNLVKAINQNPSGTY
                     HLAASLNANEVELGPDERSYIKDTFTGRLIGEKDGKNYAIYNLKKPLFENLSGATVEK
                     LSLKNVAISGKNDIGSLANEATNGTKIKQVHVDGVLAGERGVGGLLAKADQSSIAESS
                     FKGRIVNTYETTDAYNIGGLVGHLTGKNASIAKSKATVTISSNTNRSDQTVGGLAGLV
                     DQDAHIQNSYAEGDINNVKHFGKVAGVAGYLWDRTSGEEKHAGELTNVLSDVNVTNGN
                     AITGYHYTGMKVANTFSSKANRVFNVTLEKDEVVSKESFEERGTMLDASQIVSKKAEI
                     NPLTLPTVEPLSTSGKKDSDFSKIAHYQANRALVYKNIEKLLPFYNKSTIVKYGNLVK
                     ENSLLYQKELLSAVMMKDDQVITDIVSNKQTANKLLLHYNDHSSEKFDLKYQTDFANL
                     AEYNLGNTGLLYTPNQFLYDRDSIVKEVLPELQKLDYQSDAIRKTLGISPEVKLTELY
                     LEDQFSKTKQNLGDSLKKLLSADAGLASDNSVTRGYLVDKIKNNKEALLLGLTYLERW
                     YNFNYGQVNVKDLVMYHPDFFGKGNTSPLDTLIELGKSGFNNLLAKNNVDTYGISLAS
                     QHGTTDLFSTLEHYRKVFLPNTSNNDWFKSETKAYIVEEKSTIEEVKTKQGLAGTKYS
                     IGVYDRITSATWKYRNMVLPLLTLPERSVFVISTMSSLGFGAYDRYRSSDHKAGKALN
                     DFVEENARETAKRQRDHYDYWYRILDEQSREKLYRTILLYDAYKFGDDTTSGKATAEA
                     KFDSSNPAMKNFFGPVGNKVVHNQHGAYATGDGVYYMSYRMLDKDGAITYTHEMTHDS
                     DQDIYLGGYGRRNGLGPEFFAKGLLQAPDQPSDATITINSILKHSKSDSTEGSRLQVL
                     DPTERFQNAADLQNYVHNMFDLIYMMEYLEGQSIVNKLSVYQKMAALRKIENKYVKDP
                     ADGNEVYATNVVKELTEAEARNLNSFESLIDHNILSAREYQSGDYERNGYYTIKLFAP
                     IYSALSSEKGTPGDLMGRRIAYELLAAKGFKDGMVPYISNQYEEDAKQQGQTINLYGK
                     ERGLVTDELVLKKVFDGKYKTWAEFKTAMYQERVDQFGNLKQVTFKDPTKPWPSYGTK
                     TINNVDELQALMDQAVLKDAEGPRWSNYDPEIDSAVHKLKRAIFKAYLDQTNDFRSSI
                     FENKK"
     gene            complement(24578..25756)
                     /locus_tag="VQU19_000829"
     CDS             complement(24578..25756)
                     /locus_tag="VQU19_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480101.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNC
                     VCRNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLPLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWILNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
     gene            complement(25926..29576)
                     /gene="addA"
                     /locus_tag="VQU19_000830"
     CDS             complement(25926..29576)
                     /gene="addA"
                     /locus_tag="VQU19_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HET2480102.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMAERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKETFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEICSLNQESDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FAKLGQLSDQITILDYQERYHQDTWKLAKTFQTFMSHFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNKHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALVEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQNFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLESKEYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIDEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQIIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTALGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            complement(29573..32848)
                     /gene="rexB"
                     /locus_tag="VQU19_000831"
     CDS             complement(29573..32848)
                     /gene="rexB"
                     /locus_tag="VQU19_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HET2480103.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPVKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRADLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQITLVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQTFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQTTEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDQQGLENPAIPISPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWLEKIREE
                     LNR"
     gene            complement(33048..33203)
                     /locus_tag="VQU19_000832"
                     /pseudo
     CDS             complement(33048..33203)
                     /locus_tag="VQU19_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
BASE COUNT         9515 a         6538 c         6861 g        10410 t
ORIGIN      
        1 aaacctcaga cagaaaaacc tgaggaagaa acccctcgag aagagaaacc gcaaagcgag
       61 aaaccagagt ctccaaaacc aacagaggaa ccagaagaag aatcaccaga ggaatcagaa
      121 gaacctcagg tcgagactga aaaggttgaa gaaaaaatga gagaggctga agatttactt
      181 ggaaaaatcc aggatccaat tatcaagtcc aatgccaaag agactctcac aggattaaaa
      241 aataatttac tatttggcac ccaggacaac aatactatta tggcagaagc tgaaaaacta
      301 ttggctttat taaaggagag taagtaaagg tagcagcatt ttctaactcc taaaaacagg
      361 ataggagaac gggaaaacga aaaatgagag cagaatgtga gttctagttc tcattttttt
      421 catgaaaatg tgcaaaatat agtagattga aactagaata gtatacctct acttctaaaa
      481 cattgttaga aatcgatttg actgtcctgt tcttatttca ttttactata tcttaacaga
      541 tagtgtaaat aaagataaac tatttactgg ctaattaatc agttaaacac tagttaagga
      601 gtaatgatga aaaaaagaac aatactatta ttgatggcca gtctgttagc tcttgtctta
      661 ggagcatgtg gtttcttgga catattgatc ctggatcatt ctcatcagga ttactcttta
      721 ctgctatttt agaaactggg gtggtttgat ggaaagtatt ggtattggtc ttgttatcgt
      781 ttcacattcc aaacacattg cagaaggtgt tgttgaactg attagtaaag tagctaaaga
      841 tgttccgatt acttatgtag gaggaaccga gggcggagga attggaacga gttttgatca
      901 agtagatagg gttgtttccg aaaatccagc agatacttta cttgcctttt ttgacctagg
      961 ttctgctata aaatgttaag taaatgattt caaaatcaga aagggattgc tttgggcagt
     1021 tcctttttaa tgtaaatgta aaaggagtag aatcatagtg tttctaaatt gtgaatcaat
     1081 caaaactgat tgtgatgggg ctattctagc tttagaatcc ttcaaaaatt aaaatttaag
     1141 gcaatcaatt acttggaaga gtatgaaagc atttagttta taggaattct aggcctagaa
     1201 ttacatatgt atttatgaag ataggggtgt tcgatagtta gtattgttct gttctgaaag
     1261 atttgagctg tcagttgtat agaaagtgtt cgaatttttt ttaagtgatt aaattagtta
     1321 attgtatgag gttctttatg atataatgtt cttaatgaat tttcagaaag gaaaacctca
     1381 aattgttcta caaatttcta ctcttcgacc tcgaccacac tcttcttgat tttgatgctg
     1441 ctgaggatgt ggctttgacc caacttctaa aagaagaagg agttgcggat attcaggctt
     1501 ataaagatta ttacgttcct atgaacaagg ctctctggaa agacttggag ctgaagaaaa
     1561 tcagtaaaca agagctggtt aacacgcgct tttctcgttt atttgctcat tttggacagg
     1621 aaaaagacgg tagttttctt gcccagcgtt accaatttta cctcgcccag cagggacaaa
     1681 cactatcggg cgctcatgat ctcttggaca gcctcattga gcgtgattat aacttgtatg
     1741 ctgcgacaaa tggcattact gccattcaga caggacgttt ggctcaatct ggtctagcac
     1801 cttatttcaa tcaagtcttt atctcagaac agttgcaaac tcaaaagccg gatgctctct
     1861 tttatgaaaa gattggccag caaattgctg gatttagtaa agaaaagacg ctgatgattg
     1921 gagattctct aaccgccgac attcaaggtg gcaataatgc ggggattgat actatctggt
     1981 ataatcctca tcacctcgaa aatcacacac aagcccagcc gacttacgaa gtctattctt
     2041 accaagactt gctggattgt ttagataaaa atattcttga aaagatcaca ttttaaagga
     2101 gacgagctaa tgactacaaa aaagctaata ttactattga agagtacatt gaaatgtctg
     2161 aagttgattt taatgaagct gttaattatg aatttacatc tgacacttgt caattagcaa
     2221 atagtattta tcaatctctt tttaagtttt ttgataagaa aaatttctct ggcgatttaa
     2281 tttttacttg gaaatctcca tcattagtca aagaagggga ttatattggg agaagggatt
     2341 cacaagtaga taatcttaga gtaataggaa atatatttcc gaattatctt actaatcgaa
     2401 aatatagcct caatatgaat cgtaatggct gtatgggaga ttttcctcat gacttttttg
     2461 atatatacct agatcatgta gcaaaatatg cctacgaaca aaaagttaat aatattaaag
     2521 agtattatcc tttaaaaaga gcgattttac accaagagaa tgcattgtat tttcgatttt
     2581 tttctaattt tgacgacttt ttagaaaaaa attatttaaa gactatatgg caagtttcta
     2641 aagaaactcc tttttctgaa atggatttta atatgtttaa aaatatttca gaaaagataa
     2701 tcttcgaaag aggtagtaaa atgcttaatg atttaaaaag taattataaa aaatagccag
     2761 tctttataaa ctgtattcac gtattcaaat cgtatatagt cgatttatta aatctttaga
     2821 taaactgtaa aaagtggttt ccatagccac tttttgctat aatagaggca gtaaaaatga
     2881 aggagtcggc tatggaacac tcgtcttggc atgctttgat taaggcgcaa ttacctgagg
     2941 gttatttcgg gaaaatcaat cagtttatgg agcaggtcta ttctcagggg attatttatc
     3001 cacccaagga aaaggttttt caggctctct tgacaacact gcttgaagaa gttaaggtgg
     3061 taattctagg gcaagacccc tatcacggac caggtcaagc gcagggcttg agtttttctg
     3121 tacctgactc tatcccagct ccaccatcct tgcaaaatat cttgaaagaa ttgtcagatg
     3181 atatcggagt taagaaatct catgatttga cagcttgggc tgagcaagga gtcttgcttc
     3241 ttaatgcttg tttgactgtt cctgctggac aggccaatgg tcatgctggt caaatctggg
     3301 agccttttac tgatgctgtg attcaggtgg tcaatcatct agatagacca gtcgtttttg
     3361 tactctgggg agcttatgca cgtaagaaga aggccttagt taccaatcct catcacttga
     3421 ttatcgaatc agcccatcca agtcctttgt cggtttatag aggattttgg ggttccaagc
     3481 ccttttccaa ggccaatgca ttcttaaaag agacaggaca agagccaatc gattggctta
     3541 gataaggaga aaatatgcct cagttagcga cgatttgcta cattgataat gggaaagaac
     3601 tgctcatgct ccatcgtaat aagaaaccca atgatgtcca tgaagggaaa tggattggtg
     3661 tgggtggtaa gctagagaga ggagagacgc cccaggaatg cgcggcgcgt gaaatccttg
     3721 aagaaacagg gctcaaagcc aagccagttc taaaaggtgt catcactttt cctgaattta
     3781 caccagattt agactggtac acctatgttt ttaaggtgac ggagtttgag ggcgacttga
     3841 ttgactgcaa tgaggggacg ctagaatggg ttccctatga cgaggttttg agcaagccga
     3901 cttgggaagg tgaccacacc tttgttgagt ggcttttaga ggataaaccc ttcttttcag
     3961 ccaagtttgt ttatgatggg gataaattgt tggataccca agttgatttc tatgaataaa
     4021 ggagaaagca gatgctacta atcaaaaatg gtcgtgtaat ggatcctaag tctggtttgg
     4081 atcaagtttg tgatgtctta gttcaagatg ggaaaattat caaaattgcg cctgagatca
     4141 cggaagaagg agcagaaacg attgatgcta ctggtcttgt ggttgctcct ggtttggtcg
     4201 atattcatgt gcatttccgt gaacctggtc aaacacataa agaagacatt catactggtg
     4261 ccctggcagc cgctgcaggt ggttttacta ctgtcgtcat gatggctaat accagtccaa
     4321 ccatttcaga cgtggagact ttgcaagcag ttctccagtc agctgccaaa gagaagatta
     4381 atgtcaagac agttgcgacc attactaaaa actttaatgg taaaaacttg actgacttta
     4441 aggcgctctt agaagctggt gcggttggtt tctctgatga cggtattccg cttgagagca
     4501 gtaagattgt caaggaagcc atggaggaag ccaaaaaact caataccttt atcagccttc
     4561 atgaggaaga tccaggtttg aacggtgttc ttggctttaa tgaaaatatt gctagagaac
     4621 atttccatat ctgcggtgct actggggtgg ctgagtacgc tatgatggcg cgtgatgtca
     4681 tgattgccta tgcaactaaa gcccatgttc acatccagca tttgtctaag gaagaaagtg
     4741 ttaaagtagt ggagtttgct caggggttag gtgcagaagt cacagcagaa gtagcgccac
     4801 agcatttctc taagacagaa gcacttcttt taacacaagg tagcaatgct aagatgaatc
     4861 caccgcttcg tttggaatca gaccgtcgtg ccgttatcga aggtctcaaa tcaggtgtca
     4921 tcacagttat tgcgactgac cacgcgcctc atcatgtaga tgaaaaaaat gttgaggata
     4981 ttaccaaagc gccatctggt atgactggct tagaaacatc cctgtctctc ggcttgacct
     5041 atttagtaga agctggtgag ttgagcttga tggaattact tgaaaaaatg acatacaacc
     5101 cagccaagct ttacaacttt gaagcaggtt acttggctga gaatggtcca gcagatatca
     5161 ctatttttga tgccaaggct gaccgccttg tggactccca ttttgcttcc aaagcagcta
     5221 attcaccatt catcggtgaa accttaaaag ggcaggttaa atataccatc tgtaagggac
     5281 aaatcgtcta tcaagcttga taggagttag aatatgaatt attttcgaaa acgtagggag
     5341 agacaagcga aatctaatag tggaatttac tgtcccgcag ctaatcgttc caaaattcaa
     5401 tatgaaacta aagaaaaagc tgaccatgcg gttcaatatg ataacggagg tttagttaga
     5461 agctattatt gtcgtacatg tgcgtgttgg catactactt caaaatctaa taaacctccg
     5521 ctaagtttga aaaactatgg tctgaaactc tttggtttag ataaatcaga atagaaagag
     5581 aagtatgtat aagacaaagt gtttacgaga gaagttagta ttatttttaa aaattttctt
     5641 cccaatcctg atctaccaat ttgccaatta ttctgcctct tttgttgata ctgcaatgac
     5701 aggtcaatac aacactatgg acttggctgg tgtatctatg gcaaccagta tctggaatcc
     5761 tttctttaca tttctaacag ggattgtgtc agccttggtg cctatcattg gtcaccatct
     5821 tggtcgaggc aaaaaggaag aagttgcgtc tgatttttac caatttattt atttggcctt
     5881 gggcctatct gtggtcttgc tggggatggt acttttcttg gcaccaacaa tcttgaatca
     5941 tattgggtta gaagcagcag tagcggcagt agcggttcgc tatctttggt ttttatctat
     6001 cgggattatc cccttgttgc tctttagcgt cattcgttcc ttgctggatt cgctgggctt
     6061 gaccaaactg tccatgtacc tcatgctttt gttactccct ctcaatagcg gatttaacta
     6121 tctcttgatt tacggtgcct ttggtgttcc agaactggga ggggctggtg ctggtttagg
     6181 aacatccttg gcctactggg tcttgcttgg gatttctgtt ctggttttat ttaaacagga
     6241 gaagctcaaa gccttacacc ttgagaaacg aattccactt aatatggata aaattaagga
     6301 aggagttcgt ttaggtctgc ctattggggg aactgtcttc gcggaagtgg ctatcttttc
     6361 agtggttggc ttgattatgg ctaagttttc gtccttgatt atagctagtc accagtcagc
     6421 tatgaacttt tcaagtctta tgtacgcctt tcctatgagt atctcatcgg ctatggctat
     6481 tgtcgtttcc tatgaagtgg gagccaagcg atttgatgat gcgaaaacct atattggtct
     6541 aggaagatgg actgccctca tttttgcggc cttcacctta accttccttt acatttttag
     6601 gggaaatgtg gccagtcttt atggtaacga cccaaaattt atcgatttga cagcgcgttt
     6661 tttaacttat agtcttttct tccagttagc agataccttt gcggcgccgc ttcagggaat
     6721 tttgcggggg tataaggata cagttattcc tttttacctt ggtttgcttg gttattgggg
     6781 cgtagcaatc cctgtggcta cgctatttga ttccctaaca gattttggag cttattctta
     6841 ctggatcggc ttgattatta gtttgattgt gagtggggcg ctctaccgtt ggcgtttaac
     6901 tgtgattatg aagagatttg aatctttagc aaaatccaaa cgctaaaaag tttgtgaaaa
     6961 aatattcttg ataagaaaat cccttgtttt cacggggttt tcttttttat tttgtgaaat
     7021 ttcttttaga aaaactttga cagtatttgc caaaaacggt aaaatagtaa ggtaagaaga
     7081 aagttagaaa ggcaagaaga tgtcaacttt agataaaaat cttttgctag aaatgttccg
     7141 taagatggaa gaaatccgtc gcatggactt aaaaattgca caattagtaa agaaagggaa
     7201 agtgccagga atgacgcact tttctgttgg tgaagaggca gctaacgtgg gggctatgtt
     7261 agctctcaat ccagatgatc tgattacctc aaaccaccgt ggacacgggc aagctattgc
     7321 taaagggatc gacctcaacg gaatgatggc tgaaatcctt ggtaaataca ctggaacctg
     7381 taaagggaaa ggtggatcta tgcatatcgc tgaccttgat gctgggaacc ttggtgccaa
     7441 tggtatcgta ggtggtggta tggggatcgc tgtcggtgca gccctcagtc agcaaatgca
     7501 aaataccggt aaaatcgttg tctgcttctt tggagatggt gcgaccaatg aaggtgtttt
     7561 ccacgaagca gtgaacatgg cttctatctg gaacctgcca gtcattttct attgcattaa
     7621 caacggttac ggtatctctg cggatatcaa gaaaatgacc aatatagaac atatccatca
     7681 acgtagcgcc gcttatggaa ttcctggaat gttcatcgaa gacggtaaca atgtcatcga
     7741 tgtctatgaa ggatttcaga aagctgtaga ccatgttcgc agtggcaatg gtccagtctt
     7801 gattgaaagt gtaacttatc gctggctcgg tcactcatca tctgaccctg gtaaatatcg
     7861 tacgcgtgaa gaagtggaat tgtggaaaca aaaagatcca atcgaaaacc tccgcaatta
     7921 ccttattgaa aataacattg caagtgccga agaattggaa gaaatccaag cgcaagtaaa
     7981 ggaagcagta gaagcttctg ttaaatttgc agaggaaagc ccattcccac cgcttgaatc
     8041 agcctttgaa gatatttacg cagactaagg agaaagagat aaaatggaaa caaaaacaat
     8101 gtccttccgt gacaccatta tccttgctat gtctgaggaa atgcgtcgcg atgaaaatgt
     8161 gttcttgatg ggagaagacg tcggtgtctt cggaggagac ttcggtactt ctgttggaat
     8221 gcttgaagaa tttggtccag aacgcgtccg tgactgtccg atttctgaag ctgccatctc
     8281 tggagcagca gcaggagcag ccatgacagg acttcgtcca atcgtcgata tgaccttcat
     8341 ggacttctct gttattgcca tggacaatat cgtcaaccaa gctgctaaaa cacgttacat
     8401 gtttggtggt aaaggtcagg ttccaatgac tgttcgttgt gcagctggta acggagttgg
     8461 ctctgccgcc cagcactcac aatctctaga gtcttggttt actcacattc caggacttaa
     8521 ggttgtggca cctggaacac ctgcggacat gaaaggcctg cttaagtctt ctatccgtga
     8581 taaaaaccca gttattatac ttgagtacaa gtcagaattt aaccaaaaag gggaagtgcc
     8641 agttgatcca gactacacaa ttccacttgg ggttggtgaa atcaaacgcc aaggaacgga
     8701 tgtaacagtt gttacttatg gaaaaatgct tcgccgtgtg gttcaagctg ctgaagaatt
     8761 agcagaagaa ggaatttcag ttgaaattgt tgacccacgt acccttgttc cgcttgataa
     8821 ggatatcatc ataaactcag tgaagaagac tggtaaggtt gttctggtca acgatgccca
     8881 caaaacaagt ggctatatca gtgaaatttc agctattatt tcagaatcag aagcatttga
     8941 ctatctagat gcaccaatcc gccgttgtgc aggagaagat gtgccgatgc cttatgcaca
     9001 aaacctagaa aatgcaatga ttccaacagt tgaaagtatc aaagatgcaa tccgaaaaac
     9061 ttataacaaa gaatagagtt acataagata agttatgtaa ataaaataaa gctgacgaga
     9121 aactttgtat cttttaggtg cagagctctt cgtcattaat atcttatatt cgagcacggg
     9181 ctaaaagctc ggaaaaaaga taaatctcct tggcttcatc gaagccatcg tcgatttcct
     9241 atttttcagt cgcttttgac gccctttgta tcataaatag aattggagag gtcatggctg
     9301 atgacaagct aagagcgact cctgcagcta gaaagttagc ggatgattta gggataaacc
     9361 tctacgacgt ttctggctca ggtgcaaacg gtcgtgtcca caaagaagac gtggaaactt
     9421 ataaagacac aaacgtggtt cgcatttcgc cacttgcaaa acgaattgcc ctcgaacata
     9481 acattgcttg gcaggaaatc caaggaaccg gtcatcgtgg taaaatcatg aagaaggatg
     9541 ttttggccct gcttcctgaa aatatcgaaa acgatagcat caaatctcct gctcagattg
     9601 aaaaagtgga agaagtccct gataacgtaa caccatatgg tgaaatcgag cgtattccaa
     9661 tgacaccaat gcgtaaggtt attgcccaac gcatggttga atcttacttg actgcgccaa
     9721 ccttcaccct caactatgaa gttgatatga ctgaaatgtt ggctcttcgt aagaaggttc
     9781 ttgagccaat catggaagca actgggaaga agactactgt aacagacctt ctttcgcttg
     9841 cagttgttaa gactcttatg aaacacccat acatcaacgc ttcattgaca gaagatggca
     9901 agactattat cactcacaac tatgtcaatc ttgccatggc agttgggatg gataatggat
     9961 tgatgacacc tgttgtttac aatgctgaga agatgagtct ttcagaacta gttgtagcct
    10021 ttaaggatgt tattggccgt accttggatg gtaaattggc tccaagtgag ttacaaaatt
    10081 caacattcac aatcagtaat ttgggaatgt ttggtgttca gtcctttggc ccgattatta
    10141 accaacccaa ctcagctatc cttggtgtca gttcgacaat cgagaagcca gttgtcgtca
    10201 atggtgaaat tgtgattcgc ccaatcatga gtttaggatt aaccattgac caccgtgtcg
    10261 tagatggtat ggctggtgct aagtttatga aggacttgaa agagttgatt gaaaccccaa
    10321 tctcaatgtt gatttaagag caagagtatt catttttaag atatagataa aggaaggaag
    10381 acatggcctt agaaataatt atgccaaaag ccggcgtgga tatgacagaa ggacaaatcg
    10441 tccaatggaa taaaaaagtc ggagaatttg taaaagaagg agaaatcctt ttggaaatca
    10501 tgactgataa agtcagcatg gaattggaag ccgaagaaga tgggtacttg attgccattc
    10561 tcaaaggaga tggtgaaact gtccctgtaa cggaaattat cggttacctt ggtgaagaaa
    10621 gggaaaacat cccaacagct ggagcagcat cgccagaagc tagccctgta cctgtagcaa
    10681 gtacctcaaa cgatgatggt aagagcgatg atgcttttga tatcgttgtg attggtggag
    10741 gtcctgctgg ttatgttgca gccattaaag ctgcccaact cggcggtaag gttgcccttg
    10801 ttgagaaatc tgaacttggt ggaacctgct taaaccgtgg atgtattcca accaagacct
    10861 accttcataa cgctgaaatt attgaaaata tcggtcatgc tgcaaatcgt ggtatcgtga
    10921 ttgaaaatcc taacttcact gttgatatgg aaaaactttt agaaactaaa tctaaagttg
    10981 ttaatactct tgttggtggt gttgcaggac ttcttcgtag ctacggagtt actgttcata
    11041 aaggaattgg tacaatcact aaagacaaga acgtcttggt aaatggttct gaattgcttg
    11101 aaaccaagaa aatcattctt gctggtggtt caaaagtcag caagatcaac gtccctggta
    11161 tgcaatctcc acttgtcatg actagtgatg acattcttga aatgaacgaa gtgccagaaa
    11221 gccttgttat catcggtggt ggagttgtcg gtatcgaact cggtcaggcc ttcatgacat
    11281 ttggttcaaa agtgactgtt atcgaaatga tggaccgtat agttccagct atggatgcgg
    11341 aagtttctaa gaaccttcgc ttgatccttg agcgtaaagg aatgaccatc ttgactggta
    11401 ctaaactgca agaaatcatt gaggaaaatg gtcaacttcg tatcaaggtt gaaggaaaag
    11461 acgatatcat cgcaagcaaa gctcttcttt caattggtcg tatgccagac cttgaaggta
    11521 ttggagaggt tgagtttgaa ttggatcgtg gttgtatcaa ggtcaacgaa tacatggaaa
    11581 cttcagttcc aggcatttat gcaccaggtg acatcaacgg tactaagatg ttggctcacg
    11641 cagctttccg catgggtgaa gtttccgctg aaaatgccct taaaggaaat catgcagttg
    11701 ccaaattgaa tttgactcct gcagccatct acactctccc tgaagtagca gcagtaggtt
    11761 tgacagaaga acaagcccgt gagaaatacg atgttgccat cggtaagttt aactttgctg
    11821 ctaacggtcg tgctattgca tctgacgcag ctcaaggttt cgtaaaagtt atcgctgata
    11881 agaaatacgg agaaatcatt ggtgtacaca ttattggtcc tgcagccgca gaattaataa
    11941 acgaagcatc aagcatcatc gaaatggaaa tcactgttga ggaaatgctg aagaccatcc
    12001 acggacaccc aacttactct gaagtgatgt atgaagcgtt tgcagatgtt ctaggaatgg
    12061 ccatccattc acctaagaaa aaataaaacg aagatagatt agactggaag gttatttcca
    12121 gtctctatca tataaagtaa agggatatca tgaaatacat tatcaatcat tcaaatgaca
    12181 ctgcttttaa tattgccttg gaagaatacg cctttaaaca ccttttggat gaggatcaaa
    12241 tcttcctact ttggattaac aagccatcta tcattgttgg tcgtcaccag aacactatcg
    12301 aagaaatcaa ccgtgattat gttcgcgaaa atggtattga ggtagttcgc cgtattagtg
    12361 gtggtggagc tgtttaccac gatttaaata acctcaacta cacgatcatc tccaaagaag
    12421 atgaaaataa ggcatttgac ttcaagagct tctcaactcc ggttatcaat accctggctc
    12481 aactcggggt taaagctgag ttcacaggtc gtaatgacct tgagattgat ggtaagaagt
    12541 tctgtggcaa tgcccaagcc tatatcaacg gccgtatcat gcaccacggt tgcttgctct
    12601 ttgacgttga tttgtcagtc ctcgcaaatg cccttaaggt ttcaaaagat aaatttgaat
    12661 caaaaggtgt gaaatccgtc cgtgcccgtg taaccaatat tatcaatgaa ttaccaaaaa
    12721 aaatcacagt cgaaaaattc cgtgatttac tcttggaata catgaaaaaa gagtacccag
    12781 agatgactga atacgtcttt tcagaagaag aattggccga aatcaatcac atcaaggata
    12841 ctaagtttgg aacttgggac tggaactatg gtaaatcacc tgaatttaac gtccgtcgtg
    12901 gaaccaaatt cactagtggt aaggttgaag tctttgctaa cgttactgaa tcaaaaatcc
    12961 aagacatcaa gatttatggt gacttctttg gtattgaaga cgttgctgca gtagaagatg
    13021 tccttcgtgg ggtgaaatac gaacgcgaag atgttcttaa ggcgctaaaa accattgata
    13081 tcacacgcta cttcgctggt attagccgtg aagaaatcgc tgaagcggta gttggataaa
    13141 tcaaaaaaag aagttggcca acttcttttt ttgatattta tttacataat ttaaaatacg
    13201 tgaaatcata aactatctag agcattcttt tgttcatcat taacaatatg ggtatagagg
    13261 tcagtgactt gtgtgctggc atgtcctagt tggtgactga ctaaaacttg tgatttagtc
    13321 gcatcataga gcctagttgc tagcgtatgg cgcagtttat ggggtgttac acgtacttta
    13381 aaatcctctg agtatttagc aaccattttc tcaacgctag aagcatcgat acgattagga
    13441 acacctctgt agagagttaa aaaaagggct gtatctgttt tttccgtttt atagcgttga
    13501 ttccgaatgg ccagataatt ctctaaataa ggtttagcaa aagcagcgac attgactgag
    13561 tcacgtttgc caccttttcg agtaacatca ataaccatca tttttagatt gagatctctt
    13621 agatctagat taacagcttc agataagcga acaccagatg ccaagagaag ggcaataatg
    13681 gctaaatctc gttctttatt tttgttgaat gatgagagag ctcgatttga aagctgttgt
    13741 gggtgctctt gatcgatata agttagaaaa ccttctgttt catcacctag aaagagtttt
    13801 tgcttgatat tttcagctct ggcagcaagg gtttctttct ttttcttggt tgaaactttt
    13861 ttcattacat tacgatagaa ataaggttcc ccctgatcgt tttcaacctc ctcggttaga
    13921 tacttgtaaa gactagaaag tgctgataag gttcgattga tagttgtctg tgaaacacct
    13981 tgttttgttg tattagcatt cagcaaggga cgttcacgta gataaaggat aaaggattcc
    14041 atgtctttct tagacatatt ttccaaaact gataaaggaa tatcggatat tttatcagcg
    14101 tttgaaatac cagactccaa aacccagctg aaaaatcggt catattcctt aaggtattcg
    14161 tacagggttg taaaactgta gggcacagcc agcttagatt ggtagtattc cagaacatac
    14221 cagggcatga gttgttttag tttgtcgatt cgttccagta aaatctcacg tttcatgtat
    14281 tttctccata agtaagtata ctagtagtat agcatagact tgtatatttt tcaagaaaat
    14341 tatagttttt cagaaagatg ttataggagt ttttcaaagt gataaaaaga cttagaccta
    14401 caaacaaaac agaataagga aaataataaa aatctcaccc actaaacttc tgttaatact
    14461 acataactga agagctatat aaggagctat gagatacaaa acacattgta taatagattg
    14521 aaactagaat agtacatctg gacttctaaa acattgctag aaattgattt gattgttctg
    14581 attgttttat cctatttcta tttcatttca ctatataatt gctattgttt tctttttcat
    14641 gattttaatc ttactgtaca gatttgatac agtaaactcc tttctagctt tatactttat
    14701 catttctaac ttaattatag tcttattttt aataaagttc aattatttat atgtaaaatt
    14761 cctcatcagt aaaaaataac cgatctcatt tctgagaatc ggttttctaa ataaatcaag
    14821 ctgagtattt acataacata aattatgtaa atactcatac tacaacaaca aatctttgac
    14881 ttttccaatt tcactttttg gaataaccag gtgaatcata tcacccagat acattctggt
    14941 tgagccgtta actgtttggc tcttgccatt atggacttga gttgtgatga ggacgttgtg
    15001 tggtaagttg agttcatgaa cttgtttccc agcaatttta tcagaaactg gtatttcgat
    15061 aagtgtaact tctccttcgc tagatacttc ttctggaagc attttttcca gcatggcttc
    15121 atagactggc gtacctttga gcaaatccat gataatataa gaaacaagag tgacaagacc
    15181 aagtggcatg aggttgcgaa tatctcctac catctcagtt acgaggatca tagcggttaa
    15241 gggagctttt gatatggctc caaaatagcc actcattcct agaatgacaa atatagggaa
    15301 ttgctcttga ctgacaagtc caagattgac acagataaca ccaactaagg aaccaagcaa
    15361 agaaccaaga gctaaaatgg ggaggaaaat tcctcctggc agtccacttc catagctaat
    15421 catactccaa ataaagcgga tcaaaaagta agctaataaa acttggaaac taaaattttg
    15481 ttcagttaaa gaaaggacaa gctgatttcc gccaccaatg atttgaggta agaagattcc
    15541 gactggtatg ataatgataa aagccaagat gggataataa gccctatcca aatggatttt
    15601 ttgaccaatc aagtcataaa ctcttccaac gtttaataca gctttctcat agagaaaacc
    15661 tgaaaatcca aggaaaattc ccatgacgag atatatccaa tactggtcta gggtcatggg
    15721 aggaatgtta tctggcatat ccaatactgg tgtcaaaccg aacatgagta gagacacaaa
    15781 gtttgctacg atgctggctg ctagagttga gacccagaaa aagcgcgaaa aatggtgata
    15841 gacttcttct acaacaaaga gaagtgctgc aataggagca ttaaaggctg cggctaaacc
    15901 tgctgcagct ccactggcaa tcaaggaacg ttcctctact ggactggatt tgagccactt
    15961 ggcaattcct ttaccaccaa ctgctccaag ttgaatgctg ggtccctctc gacccagcat
    16021 gagtccactg gcaatagcaa gaatacctag cacatatttt ttccaaagaa tgccccacca
    16081 gttgagggac atgaggcctt tcagttcggc ttcgacttga ggaattcctg agcctttaat
    16141 atctttttct gaccgtgtta gtttggcact gagccaacag atgagtatat aaaacaaaac
    16201 cagtacaaaa agattgcgca ctaagtaccc ttgatcttga taaactcctt gtatcaggtg
    16261 gaagcccttt tcaattaaga aacgaaagga tccgacgata attccaacga tgaggccgac
    16321 aatgattcct cgaccaactt gggatagtat agtgctggat gcaaaggcga attctttctt
    16381 agaacggact atttccgact gttcctccat ggtatttcct ttcaattaac tttctttttt
    16441 acctaaaacc agtgatttaa cgggttcaaa gctggttcgg tgaattgggg taactcctag
    16501 ttttgtgagg ccttccagat gtttagctgt gccatatcct gcattagtag cgaaatcata
    16561 gccagggaac tgctgatcgt attccttcat caattcatca cgtgttacct tggctactat
    16621 agatgctgct gcgatagaga gggagttggc atctcctttg ataatggagg tttgtgaaat
    16681 gggcaagtcc agtttcatgg catcaatcaa aaggtgctct ggttgagggc tgagctggga
    16741 gattgcttct tgcatggcta gtttggttgc ttcatagata ttgacttggt cgatgacctg
    16801 attatctatg ataccaattc caatcgacaa ggcttggtct tgaacgactt ggaaaatctc
    16861 cagatgtttc tttttaggaa ttttcttgct gtcgttgaga cctttaatct tacaattttt
    16921 aggtaaaata acggccgcag cgactacagg accagcaaga ggaccacgac caacctcatc
    16981 aatacctgca attaaggtca atccttgctt ataaagttct ttttcataag aaagcatgga
    17041 ttccaagcgc aaattttcat ctaattcagc ttgaatggct cttttatgct tgctgatttc
    17101 cttttgaact cctgagcgat tatccttttc aagatctaaa aaaatagggc tttctaactc
    17161 cttgactgtc acaaggagtt ctttgatttc tttaatcgtt gccatcgagg ccttccaatg
    17221 tatctaaggt atagttaccg agtttgccat cacggacttc cttcacgaag agactgtaaa
    17281 aacggtcata gtcatcacgg aaaccgaggg cgcgggtcat atccataata atcacaggcg
    17341 cttcttcttc aattttcatt tgtttgaagc gttcagccag cttttctgga taatgttctt
    17401 tgaaataatt gataccaaaa atggtaacct catccatagg aagcaactga tccttgatag
    17461 ctccagtcaa tgccaactta agtgcaacag tttcatcctc aaacttaggc cagagaatcc
    17521 ccggtgtatc caagatttcc agatctttat tggttttaag ccattgttga ccttttgtga
    17581 cccctggctt gtttccaaca acagcaatct ttttaccagc caaacggttc atcagagttg
    17641 atttaccagc gtttggaatc ccaataatca tggtacgcaa ggtttcaatc tgaatcccac
    17701 gttctttctg gcgagcaatc ttatcagcca tgagcttctt ggccgcatct gttacaactt
    17761 ttacagtcac ttgctctttg gagttgatag ctagcgtctg gattccttgt gattcaaaat
    17821 actgacgcca ttccttggtc attgctggat cagccaagtc ggccttgttt aaaatcaaga
    17881 gttttggttt atcaccaaca atcttggtta acataggatt ttgactagat agaggtaagc
    17941 gtgcatcaac taaaatcgtc acaaaatcaa caaattttaa attctcctgc acctgtcgac
    18001 gagctttaga catgtgacca ggaaaccatt gaatagtagc cattgagttt tttcctttca
    18061 tagcaaggat ttagatcccc tattttattt tactattgtt tgaacataga gagttttcaa
    18121 atgaatgatg tccaaacagt tcttgtttta tgacatagaa atctacttta tattatatca
    18181 tgccttcttt attttgtccg atgatagcct tttaccctat atagaaaaaa gccatcaaat
    18241 gatgactttt cagagggagc aaaaaactgt tcccgtcata ttatgaacca aaagaactaa
    18301 actaccaaca gctaataggc ctaaagctgt aagtgcagaa gttgatgaac ctgttgcagg
    18361 aagagtttcc tgctgataaa taagagcata acttacttca ttatcagtag gaattcctgc
    18421 ttgaatcttg gtttgttctt catcaccttt ttaaacttta tttcctaata gtaaacacta
    18481 ttttttattc tcaaaaattg aacttctaaa atcatttgtt tggtcaagat aggctttaaa
    18541 gattgctctc ttcaacttat gaacggcact gtcgatttct ggatcataat tactccaacg
    18601 tggaccttca gcatccttga gaacagcttg gtccatgagg gcttgcaatt catccacatt
    18661 attgatagtc tttgtgccat agcttggcca tggttttgtc ggatctttaa aggtcacctg
    18721 cttcaagttt ccaaactgat ccactcgttc ttggtacata gctgtcttaa attctgccca
    18781 agttttatac ttaccgtcaa ataccttttt caaaacaagc tcatcggtca ccaagccccg
    18841 ttctttacca taaagattga tagtttgccc ttgttgttta gcatcttctt cgtattggtt
    18901 tgagatataa ggtaccattc catccttaaa gcctttggca gccaaaagtt cgtacgcaat
    18961 cctacgtccc ataaggtccc ctggtgtgcc tttctcactg ctgagagctg aatagattgg
    19021 ggcaaagagt ttgatggtat agtagccatt tcgttcatag tcgccagact ggtactcacg
    19081 agctgataag atgttgtggt caatcaaact ttcaaaacta ttcaggtttc gggcctctgc
    19141 ttctgtcaat tctttgacta cgttagtggc ataaacctca tttccatctg ctggatcttt
    19201 cacatacttg ttctcaattt ttctgagagc cgccattttc tggtaaacac ttagtttatt
    19261 aacgattgac tgcccttcga gatattccat catgtagata aggtcaaaca tgttatggac
    19321 atagttctga agatctgctg cgttttggaa tctctctgtc ggatccaaga cttgaagacg
    19381 ggatccctct gtactatctg attttgagtg tttcaagata gaattaatgg taatggttgc
    19441 gtcacttggt tggtcagggg cttgcaataa gccttttgcg aagaactctg gtcccaagcc
    19501 atttcttcga ccatagccac caaggtaaat atcctgatcc gaatcatggg tcatttcatg
    19561 ggtataagta atggctccat ccttgtccag catgcggtaa gacatatagt agacgccgtc
    19621 ccctgtagcg taggctccat gctggttgtg tactacctta ttgccaactg gtccaaagaa
    19681 gttcttcata gctggattgg agctatcaaa cttagcctcc gctgtagctt ttcctgatgt
    19741 tgtgtcatcc ccaaacttat aggcatcata aaggagaatc gtacgataga gtttttcgcg
    19801 tgactgttca tctaaaatac gataccaata atcgtagtga tctcgctgac gtttggctgt
    19861 ttcacgcgca ttttcttcaa caaaatcatt gagagccttg cccgctttat ggtcactact
    19921 gcggtagcga tcataagctc caaatcctag actagacatg gtcgagatga caaatacgga
    19981 tctctctggc aaggtcagga gaggcaagac catattgcgg tatttccatg tggcactcgt
    20041 gatacgatca taaacaccga tagaatactt ggtgccagct aacccttgct tcgttttcac
    20101 ctcttcgata gtggattttt cttcgacaat gtaagcctta gtctctgatt taaaccagtc
    20161 attattgctt gtatttggta aaaagacttt tcggtaatgt tccagcgtgc taaacaaatc
    20221 tgtcgttcca tgttgactgg caagactgat accataagta tcgacattat tcttagctag
    20281 aagattgtta aagccagatt tacctaactc aatcagagta tctagtgggg aagtatttcc
    20341 tttaccaaag aagtctggat gatacataac taggtctttg acattcactt gaccatagtt
    20401 aaagttatac caacgttcta aataagttaa accgagtagc aaggcttcct tattattctt
    20461 gattttatct acaagatagc ctctggtgac tgagttatcg ctagctagac cggcatctgc
    20521 tgacaaaagt tttttcaagc tgtctcccag attttgtttt gttttggaga actggtcttc
    20581 taaatagagc tcggttaact taacttctgg agaaatacca agtgtctttc tgatagcatc
    20641 tgactggtaa tcaagcttct gcaactcagg caagacttcc ttaacaatag agtctcgatc
    20701 atataagaat tggttaggag tgtagagaag tcccgtatta cctagattat attctgctag
    20761 attggcaaaa tcagtctggt acttgagatc aaatttctca gatgaatggt cattatagtg
    20821 aagtaagagt ttgtttgcag tctgtttgtt ggaaacaata tctgtgatta cttggtcatc
    20881 cttcatcata actgcagata agagttcttt ttggtataag agactgttct ccttaaccag
    20941 gtttccgtat ttgacgatgg ttgacttatt ataaaaaggt aacaattttt caatgttctt
    21001 ataaaccaaa gcacggttag cttgataatg ggctatctta gaaaaatcac tgtctttctt
    21061 gccacttgtt gagaggggtt ccaccgttgg tagagtgaga ggatttattt ctgctttttt
    21121 gcttacaatt tgagaagcat ctagcattgt tcctctttct tcaaaggatt ccttgctgac
    21181 gacctcatcc ttctctaaag tgacattgaa aactctatta gccttactac taaatgtatt
    21241 agctaccttc attcctgtat agtggtatcc agtgatggca tttccgtttg ttacattgac
    21301 atcgctaaga acattggtca attcaccagc gtgtttttcc tcaccagaag ttcgatccca
    21361 caaatatcct gccacaccag cgactttacc aaagtgcttg acattattaa tatcaccttc
    21421 cgcataactg ttctgtatat gcgcatcttg gtctactaga cctgcaagac caccgacagt
    21481 ctgatctgac ctattggtgt ttgacgaaat ggttactgtc gctttggatt tagcaataga
    21541 cgcatttttt cctgttaaat gaccgaccag accgccaata ttgtaggcat cagtcgtttc
    21601 ataggtattg acaattcttc ccttgaaact gctctctgcg atgcttgatt ggtctgcctt
    21661 agccaacaaa ccaccgacac cacgttctcc agccagaaca ccatcaacat gaacttgttt
    21721 aatctttgtg ccattcgtag cttcatttgc tagtgaacca atatcatttt tccctgaaat
    21781 agcaacattt tttagactca gtttttctac tgtagcacca ctcaagtttt caaacagagg
    21841 ttttttcaaa ttatagatag cataattctt gccatctttt tcaccgatta aacgaccagt
    21901 aaaggtgtcc ttgatatagg atctttcatc aggaccaagc tccacttcgt tagcattcag
    21961 gctggccgct aaatgatagg ttccagaggg attttggttt atagctttga ccaggttgct
    22021 aaaggaagta aagtttgtat tttcctcttt agccttctta tcgaggtaga aggtgaaatt
    22081 gtcgacatat ttattttcta gttcttgctg gagtttctca gctttggctg tgattttata
    22141 aactgactgc ccatttcttt tctcttcagt tattgaagct actggtatat agacatcttt
    22201 aaatgctgaa gattttacct tgacaaagta agtatccgta ttctctggaa ttccatccaa
    22261 tgaaacatgt tgtctgtagg ttccattcgt ctgactatac aactcaatat cagaaacatt
    22321 tcttaattcg agttttttct ctggttctgt ttgtccattc tctgatgttg tattacctga
    22381 attttctggt tttgttgcag ttccgttttt ttctggttga tttgattctt caactggtgg
    22441 ttttgaatca ctaggtttat tggatacttc tccagtattt tcgttagcta ttttcccaga
    22501 gtttgtttgt gtttcttctg caggttgaac tggtttttct gtttcttgat ttgaggtacc
    22561 ttctactgtg ccttcatttg gatttactgg aacttcttct acagtttttt ctgaattttc
    22621 atttttagag tcattatgtt ctggtttatt tgattctcca actgaggttg tcgaatcact
    22681 aggattactg gacacttccc cagtattttc gctagatgta tctggtgata ctttctctga
    22741 attcgttgtt gattcttctg caggttgaac tggattttct gcttcttgaa ttgaggttcc
    22801 ttctgtagta ccttcatttg gatttactgg tgtttcttct gttggtttta ctggaacttc
    22861 ttcagttttt tctggacctt gttctttggt cttctcaacc ggagtttcag gttttacttg
    22921 ctcaatatta cccttatatt ctggcaatgg ggctacctgc tctggttcac ctttatcact
    22981 taccacagta tctggcgact ctggttgaac ctcagtctca cctttgtcgg tcacaactgc
    23041 ttcgggtaat gtcggttgaa cttctggttc gcctttatca cttactacag cttcgggcaa
    23101 ctcaggctga attgcgggtt caacaataga tccagactgt acgtccttat gttctacacc
    23161 agtctcaggt tgttccttta taacttgagt ttttttagta cctttttcga ctattcttgg
    23221 actaggcgca gtcgttgaag ttgaaacaat ttctcgcgaa acttcttcct tgtttacaga
    23281 gaatattctg acgatttcaa ctttcttacc taatttacct tcttgtttta ctcttacagt
    23341 tccttcagct aaatcaggat tttcttgaat ttcttcttga aaatctattt ttgtctctat
    23401 agtttcctca cgatataaga gttcaggttt gttcaattga cctgataaaa cttcatcctg
    23461 tggatttaat gtatttaccc cagtcttttc ttttggagaa atcttctcct ctttcttcgt
    23521 ttctagattc ttatgttcgg ctaattgttc ttgagaatct gaagattgtt tctcttcttt
    23581 tcttggattg attaattcag tagagaaagg tttttcaact acttgaactt ctgtcggctt
    23641 agttgaagaa acaggtgttt gttcctgaat agcttgtact gttgatggat ggtctacaaa
    23701 atttggtgta acattataat ccaccttttg ttgttttgta ggagtggctg ctgatttttc
    23761 ttgattactt acttcaaaat cagaagtcgt ttttccctct ttgatatatc caatataagt
    23821 gtaacctgaa atctctttag gaagaggtaa tttttctcca gaggtcaatt catagtccgt
    23881 attgtaattt agcaaaagat gattttctaa agcatggact gaaactaaga caccatttcc
    23941 cattcccgca accaatacta aatgtaatac cgttttattc ttaacctttt tcttggaaac
    24001 agcaaaaatt aaaattccca gagcagctaa gctagcacca gcaactaggg cttgcctctc
    24061 attcttgctt ccagtatttg gtaattccgc cagttgattt tgagaattta acttataaac
    24121 aagataataa gtttcatcat cattctccac gtatgtcgga atatcataga caagctgctt
    24181 cttttcttct gatgatagct ctgaatctgc cacatattta tagtgaactc ccgcagtttc
    24241 ttgagcatcc acagatgaac tagctaatac agacataaaa aataaacttg aaatcgttgc
    24301 agatacaagt cctactgata attttctaaa tgaaaaacgc tcttgttttt caccaaaata
    24361 cttttccatt attcctcctt gaaataaaat ttatatatgt tacaaagacc tttattatat
    24421 tagtgtatta tctattatct atagaaaagg cagtatacct taattatact cttaatttac
    24481 aaaaaagtct taaaattgag atgcgctttc atactttgtt ttatattatt tgggggtaca
    24541 ataacaccta ccatgaaatt tacacggtag gtgttactca tatcactaat cgttctaaaa
    24601 atggtttgag gcagttgagg agaattcctt ctatccagct tccttgtgct gatgagcgat
    24661 ggtcttcctg caggcttttt tttagaaaat ctcggacttg ttctggtgcg atttcaaatt
    24721 caaaggcttt cattttatag aaaaagtcga tgagatgatc tgacaggtat tcagttgaaa
    24781 agggtacttc accacttttt cgatattcta ataagagtct agaaaatcga gctttttctt
    24841 caggaagctc acgaaaatag gaattgagga tccaagtctg cttctgtttt ctttcaattg
    24901 gatcctgact ggcaattcgt tggtcttttt ccagctcttt ttggtattgt ttggccttga
    24961 tagctcgttc tgctctattt ttaccaaaaa gaattttttc ccacttgcgt tcttcttgag
    25021 tcagggtctc tgtaaagcca aagtaatctt gataagcacg ctctgcgggt cccatggcta
    25081 gaaccagatt gtctgcatat tgcttggcga ttttatccct cttcttgcgt tctttctctg
    25141 cctggatacg gagttcttgt tcgtagtcaa ttttctcctt gcctagcttg acaaggtaga
    25201 gttggtcatc cgatttccca agtaaaaagg gtttgataca cttttcaagg acttcttcca
    25261 tccgagcctt tttctttggt tccgccttgg tccaacttcc tccctgaaag acttctagga
    25321 aaagctggta gtctctctca ggcgcaaatt gattgccacg attgggtttg aaaacacctt
    25381 tttcccagag ccattttaga agtcgctcgt caaagtcact tttattgacc ttgatttttt
    25441 cctttttctg agcttttctg gttagatttt caacctttct gagcagtttt tcttcctctt
    25501 ccaattgctg gtcaaggggc aatcgatgaa aatgacgaac acagtcgcta ccaattggaa
    25561 agaggcgttg gcctgtgaca ccgttaaaga gttcataagc gtatttgatg gcatttcgac
    25621 agacacaatt gctacggcca ataccgttaa aaatcaagga aacttcattc cattccttgg
    25681 tagcttgttc ccaagtatcc gctttcgaag cctgtaaaac tgcatcgtgc agggattttc
    25741 taactggaag tgtcatgagg tctcctttct aatactcaat aaaaatcaaa gagcaaacta
    25801 gaaagctagc cgcagtcagc tcaaaacact gttttgaggt tgtagataga actgacgaag
    25861 tcagtaacca tatatacagc aaggcgaagc tgacgtggtt tgaagagatt ttcgaagagt
    25921 ataagttata cttttacaac ttgaacctcg tctttaccga gtaaaatcaa gtatttttca
    25981 atattttcaa tcgaataggc tcgtgataaa gcctcttcgt atagagctaa ctgaccacga
    26041 tagcggtcta cgagttgact tggttcatca tagcggtctg tcttgtagtc gaacagaaca
    26101 attttgtttt cgtaaagcag atagccatca aggataccac ggacaacaaa gtcttcctga
    26161 ctcttttggt ctcgtttgag catggagaaa ggttgctcgc gatagagatg gtcggtatta
    26221 gcaagaattt cctgaccgag tgctgtgtca aagaaagcaa gaattttatc aagattgatc
    26281 ttgtctctga cagcttggct agtttgaact tgtttgagtg tttctgttaa gctagcaagg
    26341 gttagttgct ggctgaggtc aattatctgc atgagttcgt gagtagcact accaatctca
    26401 gctccagtta ccttttcttt ggttgaaaaa tctggcaaat cgaagctgat tttcttgcct
    26461 actgactgac cttgaccagc aatctcgaca ccttccatat ccataactgg ttcgtagaat
    26521 ttcttgattt gacttggggt ttgaacacta ggaagttcaa tagctgcgcg gtgaagagta
    26581 ttataaactt ccacctcctt cagcatttcc agagcttctt tgatggtatc tgactgacga
    26641 ttgtctgctt gggagctatc ttggagagga ctcttggttt ccaactctcc gatagcttct
    26701 ctggtcaact gatcttcgtc aataaaacga taactaaagt tgagcttgtc cttagtaaac
    26761 actttactga tagcccaaag ccaatcttgg aaattccgtg cttgcagtct agtattgcta
    26821 tttagtttcc catttttggc tgctgggtat tccttggatt ccagcttttc acgagaaccc
    26881 ttgccgacaa gatagagctt tttctcagcc cgcgtcatag caacatacag caaacgcatc
    26941 tgctcagaat agcttgctag ctgtaattcc tcttcgttct gcctataggt cagactagga
    27001 atggagagtt tgatggtttt aggatagtgg tcttctactg cccctgtctc catcttggca
    27061 atatatttga caccaagacc attctgacga ctgagaatga cttctgacat agagtcttgc
    27121 ttgttgaaat tttgatccat attgaggata aagacgtaag gaaactccag ccctttactc
    27181 ttgtggatgg tcatgagctc tactgcatct tttggcggtg cgacggccac gcttgccaaa
    27241 tcgtgctggg cttctaagac ttggtcaatc atacgaataa aacgcgacaa acctttgaaa
    27301 ttgctctttt caaattgatc agcacgcagt gctagggcat agagattggc ctgcctagca
    27361 ggaccattcg gcaaagcccc aacatagtca taataaaaac ggtcgttgta aatcttccaa
    27421 atcaagtcat agagagagtg ggttttggca tacaagcgcc aagaagctag gatatccatg
    27481 aattgcttta gtttttcaac tagagctgtg tgaatcaagc ctttttgact acttgccatt
    27541 ttttgtgcat tgaccagttt ctcatagaga ttttcgtgga ctttatcctc tgctttctga
    27601 agggacaaac gtgctagctc atcctcatca aaaccaaaca ttggagactt cataagggca
    27661 accaaggcgt agtcttgcag gggattgtga atgacacgaa gagtgtctag catgacttgc
    27721 acttctaggg attggagata attgttttgc tctccgtcag ttttgacagg aatcccgtac
    27781 tcagacaggg cgaggagaat ctggtcatta cgactgcggc tggaggtcag aagggcaatt
    27841 tccttaaagg caacaccttt ttcttgatga agtttcagaa tctccttgat aactaagcgc
    27901 atttcgcctg ttagtttcgt ttctgtttga ctctcttctt cctcacctgt atcgtccttg
    27961 tcgtagagga gaaattctgc cttgttgtct ggattgggag tcagtttggt attggcaaaa
    28021 acaagctggt gcttgttatc atagttgatt tcaccgacct cttggtccat gagacgttca
    28081 aagacatcat tggttgctga cagcacttct gaactactac ggaaattttc cttgaggaga
    28141 atgagcttgc cttcttgggg attttgcgca tagcgttgga atttctcatt gaaaatctgc
    28201 gggtctgcct gacggaaacg atagatggat tgcttgatat ctcccaccat aaagcgattg
    28261 tggccattag acaacaattc cagcatccgt tcttgaatat ggttggtatc ctgatactca
    28321 tcgaccatga cttcatggaa gcgctcctga taagactcac gaacttgtgg gaaattctct
    28381 aaaatctcaa tggtgtaatg gctgatatca gcgaattcaa aggcattttc ctggcgtttg
    28441 cgctgacgat aagcctccac aaaatgactc ataaaggttt ggaaggtttt agctagtttc
    28501 catgtgtctt gatgataacg ttcttgatag tcgagaatgg ttatctggtc tgataattgt
    28561 cctagtttag caaactgggt ctttctctct tcgttgtagg catcagccag gggcttcaaa
    28621 tcagccttac gactggcatt agtcagagct cgaccgtttt tctccttaga gatggcgaca
    28681 acacgcgcaa gcactgcctg ataagcctga ctatcggact cctgatttag ggagcaaatt
    28741 tcatccagaa ttaactgaac attttctaaa taggcagcct ttgcaaactc cttggcatcg
    28801 ttatccagat ggtaacggaa aaagctttcc aaatcccaaa gggcttgttt gatttgctca
    28861 gtcagttttt ctttttcact ggtaaaatca gctttctcaa atcctttgag gaaagattca
    28921 ctcagccact tttgaggatt actggtggat tggaggaagt catagatttt atagacctgc
    28981 tggcgcagac cccgttcgtc cttgccacgc ccagcaaagt ttttcagcaa atgactaaag
    29041 gtctctttct gtttaccttg gtaatgcgct tcaaagacct catgaaagac ttcgttttcg
    29101 agaagaagtt gctcgctttg gttttgtaaa atacggaaat taggtgcaat atcaagcaga
    29161 taaccatgtt tgccaaggaa tttttgtgtg aaagagtcca tggttccgat ggcagcgttt
    29221 ggtaggtctg ccaactggcg tcccaagtgt tgtttgaggt cgacatcatc tgtttcttgg
    29281 attttcttgc tgattttttt ctctaaacgt tctttaagtt cagttgcagc cttgacggta
    29341 aaggttgaga taaagagttg agaaatttcg acaccacgcg ccaattggtc cagaatgcgc
    29401 tctgccatga caaaggtctt tccagaacca gccgatgctg agaccaggat attctgacca
    29461 gaagtgtaga tagcttcgat ttgctcggca gttttctttt gttccttgct cgaatttgct
    29521 tctgcttctt gcagtttttg aatctcctcc tcacttaaaa agggaataag cttcatcgat
    29581 tcaactcctc tcttattttt tcaagccaag cttgcttgag tttttctccg accagacgct
    29641 tgccatcagc taggtccaac ttttctagga aacgggcttg gcccagatgg taattggctt
    29701 caaagcctgt aatagcctga tgttgctgga cgtatggggc aatgcttctg ccattttcag
    29761 tataaggatt gatggcgaac cggcctgcta aaatcttctc agcagctttc ttgtaaagat
    29821 aggcattgta gtccagtagg agctgaaatt cctcatctgt cagttgattc gccttgtttt
    29881 tgttataaaa ttcgcctaaa taactgcttt ctttttccaa gaagagccct tggtatttca
    29941 tagatttgct ggcttctacc actgctcctg ccagactttt taccgccatc agagattgga
    30001 caggttcagc catttccaag tacatggcgc cgaaaaagtt ctgctcccct tctcttttta
    30061 gggcagcaag ataggttggt aactgagaat tgagcccatt aaagaaatga ggaaactgga
    30121 actgagtcag actggatttg tagtctacta ctcctatcgc tccattagct ttcaaacggt
    30181 caatccggtc caccttgcct cgtacaaaga cactgcgtcc attgtctaat tgaataaagg
    30241 cttggtcttt tccaccaaaa tttgcttctt ctttgattgt ttcgatggct ggattgtgtc
    30301 ggagaatatg tccagttgtc cgtgcaacat caagcaaaac ttccttggta aactgggctt
    30361 ccaaactttc ttgataaata gcttcaaatt cgcgttcttg actggtttct tgaatagctt
    30421 gttctagacg ttggtcaaag gaatcttcat taggcaactg caaggcgcgt tcaaagatac
    30481 gatgcaagaa attcccgtga ctacgggcat caggacgcaa acgtaattcc tcctgcaagc
    30541 ctaaaacgta gcgtaggaaa taactgtatt cattgcgata aaactctgtc aaacccgacg
    30601 tagacaggta aaactcctgt ttggcaggat agagagcttg caaggtgtcc ttggctaagg
    30661 tcttgctgct tggactgatt gggatggctg gattttccag accttgctga tctagttttt
    30721 tacctatgac acgcgacaga accttgacaa aagtcaaatc ttgctcagta tcgctcatct
    30781 caccctgctg gtgataggca accagactag acaaaagact gtgataggac cccatatcct
    30841 ccttagacag tcctttgtga ttcatcctct tctctctccg cctaaatcca aaatggatca
    30901 actcttgaag ataggcagat tccttacttt cactttcgtt aaaaaggctt ggagccgaca
    30961 agaacaactg cttacgagca gaattgacca aggaaagcat agtgtagcga tttttcttga
    31021 gattttcact gctggcaatc agtaattgaa cgccttcttc ggtcgtttgg tttaggtttt
    31081 gcctttcttc atctgtcaga agactggtgt tttgagaaat ttttggtaaa ttgtcctgag
    31141 ttagtccaat agcatagaca aagtcagcag tcaatggtgc aatcaaatcg taactctgca
    31201 ccagaacagt gtccactgtt gctggaatgg tacggtattg ggacaaactc attccagaat
    31261 ggagcaaggc taggaagtct tccagactaa cctgtgaacc agcaaaaaca gtcgcaaatt
    31321 gttctaaaac atggcagaaa gccttccaaa cttcggcttg tctttcctgt tctacagctt
    31381 ccaaagtggt tgtcaaatct tgtaactgct tggtcacagc tccttctttt agaaagacac
    31441 tccatttttg taggaggttt tcagcctttt gttttcggct ggcaaagagg gtttcaagag
    31501 gtgctaaaat tctcaggcgg aggacattca aacgctcaag attaaatttt ccatggtggg
    31561 atttggtgaa agtttgctga aaggctggca agccattgat accaagatag cggatatatt
    31621 gctcaaaagc atcaatatca gactgactga ggtcagtata caaatcagtt ctaagaagat
    31681 taatcaaatc ctcctgacga aaacggtaac gttttaaagc taaaatagac tcgacaaact
    31741 gagtcaaggg atgatgagcc atggcttcgc ttctaccaag ataaaaagga atctgatact
    31801 ggtcaaaaat ggttttgaga gataactggt aagaagctac atcccccaag agaatacgaa
    31861 aatgcttgta gctcaggtct gagttctcat gtaatttctg acgaatgcta cgggctacta
    31921 gctccaactc ctccttttgc gtcaaacaag accagatttg taaattttca cggtctttct
    31981 catcgacatc caaagcgagt tctgaaaagt cataagaaga ctccaacaaa cgagaggcct
    32041 tgtcaaaact atccatcttc tcatgagttt gagaacagtc ctgagcaggc gtttggtatt
    32101 tagaagccag atgatggaga aattttacgc tggcttggta gagattgccc tcgctaaaag
    32161 gactggtata ggctttctta ctagcataag ccccgataac aatctcaaca cctttgccgt
    32221 gaagtaagtc cacaacccgc tcttcctcag cagaaaaacg agtaaagccg tcaatgacca
    32281 aggtgatttg attaaaatca ctacttacct tgtcattctc aatagcctca atcaaatggg
    32341 acaactgact tccctgggct aactgacctt gattaagata ggctgttact ttctcaaaaa
    32401 tcaagagtaa atccgccctc ttatcctcat ctgttaaatt ctccaagtcc aaaaaactca
    32461 tctgagattt ggtcatctca tggtaaagct caattaactg ctggatcaat tgaggatcct
    32521 gcttaatagc gccataaaca cgcaagtcct tgggatcgag ttcggcaagg catttgtaaa
    32581 aggccaaccc aagaccgata tcatcaagag tagttttaac tggtaaatca ttcaagacca
    32641 gataacgagc catttgagca aagcgcgtga cggtaatcga aaaagaagcc tgctgggaca
    32701 agcattccag cacggcgcgt tccttttcaa aagaaagaga gttgggggca atgtagaaga
    32761 cccgcttgcc agctgcaact agctcttctg cctctcttgt tagaatttct gtcaaagaag
    32821 ttcgaatatc agtataaagt aatttcatct cagcctcgtt ggaatttttc atcaccctat
    32881 attataccat gattagcctc gtaaatctgt taaaatattt aggccatcct ttcttttctt
    32941 catcatctgc taaatcttaa atacttagct ttacttgtat tagatagaat aagtctggct
    33001 actgaaaatc acataataaa aaagcctcgg taacaaggct ttgagtttta tgattgtttc
    33061 ttaggtacgg aatacacttc aatgtgttgt cccagtatct taatgtcgac tggtagattg
    33121 tctgatttat cgccatcaac atcggactct aattcgatat cagaagaagt tttaatatta
    33181 cgtgccttta tatattcaat attcttgata gaatgattga actatagtaa attgaaacta
    33241 taatagtaca ccgtggatgc taaaatattt ctagaaatta atttgatttc cctaatcaag
    33301 ctgttcgtat cttatttcaa tcta
//
LOCUS       DAVBCA010000019        32720 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.019, whole genome shotgun sequence.
ACCESSION   DAVBCA010000019 DAVBCA010000000
VERSION     DAVBCA010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32720
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.019"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(472..1161)
                     /gene="rplA"
                     /locus_tag="VQU19_000833"
     CDS             complement(472..1161)
                     /gene="rplA"
                     /locus_tag="VQU19_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HET2480104.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMGLVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(1368..1793)
                     /gene="rplK"
                     /locus_tag="VQU19_000834"
     CDS             complement(1368..1793)
                     /gene="rplK"
                     /locus_tag="VQU19_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HET2480105.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAVRMIEGTARSMGFTVID"
     gene            complement(1916..2632)
                     /locus_tag="VQU19_000835"
     CDS             complement(1916..2632)
                     /locus_tag="VQU19_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HET2480106.1"
                     /translation="MKKRYLVLTALLALSLAACSQEKAKNEDGAAKTEQTAKADGTVG
                     SKSQGAAQKKAEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELVKLI
                     KAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKEAADRYSARPGYSEHQTGLAFD
                     VIGTNGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYFGFEGGDYVD"
     gene            complement(2635..3105)
                     /locus_tag="VQU19_000836"
     CDS             complement(2635..3105)
                     /locus_tag="VQU19_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HET2480107.1"
                     /translation="MCLICQRIELIKKGENPYFVKELETGYLVIGDHQYFAGYSLFLA
                     KEHVSELHHLEKKTRIRFLEEMSVVQEAVAKAFAAEKMNIELLGNGDAHLHWHLFPRR
                     RGDMNGYGLNGRGPVWWIPFEEMTAEICQSKPDEIKRLVERLSSEVDKLLEIKE"
     gene            complement(3107..4144)
                     /locus_tag="VQU19_000837"
     CDS             complement(3107..4144)
                     /locus_tag="VQU19_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HET2480108.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGQKVLGTILIHQTSCHVYKDAGTAERTQDNMEVRLDVKVSNEKETRALGIEVG
                     DFISFDPRTVVTDTGFIKSRHLDDKVSAAMLLNLLRIYKKEKIELPVTTHFAFSVFEE
                     VGHGANSNIPAQVVEYLAVDMGAMGDDQQTNEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVVATERM
                     VDAYLKSALVD"
     gene            complement(4242..5567)
                     /gene="brnQ"
                     /locus_tag="VQU19_000838"
     CDS             complement(4242..5567)
                     /gene="brnQ"
                     /locus_tag="VQU19_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HET2480109.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(5738..5830)
                     /locus_tag="VQU19_000839"
     CDS             complement(5738..5830)
                     /locus_tag="VQU19_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET2480110.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            complement(5873..6025)
                     /locus_tag="VQU19_000840"
     CDS             complement(5873..6025)
                     /locus_tag="VQU19_000840"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET2480111.1"
                     /translation="MKEIAFDAFYQLYQNDQLSLVDVREVDEFAALHLEGAHNLPLSQ
                     LADSYD"
     gene            complement(6185..6763)
                     /locus_tag="VQU19_000841"
     CDS             complement(6185..6763)
                     /locus_tag="VQU19_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HET2480112.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPCT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(6817..8217)
                     /gene="pepV"
                     /locus_tag="VQU19_000842"
     CDS             complement(6817..8217)
                     /gene="pepV"
                     /locus_tag="VQU19_000842"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HET2480113.1"
                     /translation="MIAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGAARLHSFTGGLREN
                     MVPESATAVVSGDLTDLQAKLDAFVAEHKLRGELQEEAGQYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVASVSLSEHGHTPHYVPMEDPLV
                     QTLLNVYEKQTGLKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(8230..8835)
                     /locus_tag="VQU19_000843"
     CDS             complement(8230..8835)
                     /locus_tag="VQU19_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HET2480114.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDLKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDDKLEPSYRLPVDEIIEKR"
     gene            9006..9806
                     /locus_tag="VQU19_000844"
     CDS             9006..9806
                     /locus_tag="VQU19_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2480115.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATINFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(9988..10821)
                     /locus_tag="VQU19_000845"
     CDS             complement(9988..10821)
                     /locus_tag="VQU19_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HET2480116.1"
                     /translation="MNHKIAILSDIHGNATALEAVIADAKTQGASEYWLMGDIFLPGS
                     GANDLVALLKELPITASVRGNWNDCVLEALDGQYGLEDPQEIQLMRMTQFLMERMDPA
                     TTVWLRSLPLLEKKEIAGLRFSISHNLPNKNYGGDLLVENDTEKFDQLLDAETDVAVY
                     GHVHKQLLRYGSQGQQIINPGSIGMPYFNWEALKNHRAQYAVIEVEDGELVNIQFRKV
                     AYDYEAELELAKSKGLPFIEMYEELRRDDNYQGHNLELLASLIEKHGYVEDVKNFFDF
                     L"
     gene            complement(10811..12658)
                     /gene="uvrC"
                     /locus_tag="VQU19_000846"
     CDS             complement(10811..12658)
                     /gene="uvrC"
                     /locus_tag="VQU19_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HET2480117.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGIHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDEAYFKSMAQEVSDFLKGQDDKIIDDLKSKMAVAAQSMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDTKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGRPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMRHFKSLTKIKEA
                     SVDEIVEVGVPRAVAEAVQRKLNPQETEILLQVAEERVDYQTEGNHNKP"
     gene            complement(12698..13399)
                     /locus_tag="VQU19_000847"
     CDS             complement(12698..13399)
                     /locus_tag="VQU19_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HET2480118.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKMGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWAQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETSE"
     gene            complement(13478..14710)
                     /gene="murN"
                     /locus_tag="VQU19_000848"
     CDS             complement(13478..14710)
                     /gene="murN"
                     /locus_tag="VQU19_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HET2480119.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSEYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(14715..15935)
                     /gene="murM"
                     /locus_tag="VQU19_000849"
     CDS             complement(14715..15935)
                     /gene="murM"
                     /locus_tag="VQU19_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HET2480120.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(16047..16826)
                     /locus_tag="VQU19_000850"
     CDS             complement(16047..16826)
                     /locus_tag="VQU19_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HET2480121.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALATNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIRDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(16895..18556)
                     /locus_tag="VQU19_000851"
     CDS             complement(16895..18556)
                     /locus_tag="VQU19_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HET2480122.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPEHIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKILSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEDYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(18731..20953)
                     /gene="recJ"
                     /locus_tag="VQU19_000852"
     CDS             complement(18731..20953)
                     /gene="recJ"
                     /locus_tag="VQU19_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HET2480123.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAVVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKTYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            21230..21988
                     /locus_tag="VQU19_000853"
                     /pseudo
     CDS             21230..21988
                     /locus_tag="VQU19_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            22028..22792
                     /locus_tag="VQU19_000854"
     CDS             22028..22792
                     /locus_tag="VQU19_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HET2480124.1"
                     /translation="MISLFGLAAAKPVQADTSIADIQKRGELVVGVKQDVPNFGYKDP
                     KTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIATFTITDERKK
                     LYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITELGKKKGLKFK
                     FVELGSYPELITSLHAHRIDAFSVDRSILSGYTSKRTELLDDSFKPSDYGIVTKKSNT
                     ELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            22805..23482
                     /locus_tag="VQU19_000855"
     CDS             22805..23482
                     /locus_tag="VQU19_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2480125.1"
                     /translation="MIDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILAHIFVEFYQNTPLLVQFVIVFYGLPLISDHTIMIPIYWTAVLCMGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLIILPQTFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            23492..24151
                     /locus_tag="VQU19_000856"
     CDS             23492..24151
                     /locus_tag="VQU19_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2480126.1"
                     /translation="MESILEVLTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPVLRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNTVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLCILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            24446..25636
                     /locus_tag="VQU19_000857"
     CDS             24446..25636
                     /locus_tag="VQU19_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HET2480127.1"
                     /translation="MKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTNNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(25957..26838)
                     /locus_tag="VQU19_000858"
     CDS             complement(25957..26838)
                     /locus_tag="VQU19_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HET2480128.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(26979..28307)
                     /gene="vncS"
                     /locus_tag="VQU19_000859"
     CDS             complement(26979..28307)
                     /gene="vncS"
                     /locus_tag="VQU19_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HET2480129.1"
                     /translation="MKRTGLFAKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGATMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVVQD"
     gene            complement(28304..28960)
                     /gene="vncR"
                     /locus_tag="VQU19_000860"
     CDS             complement(28304..28960)
                     /gene="vncR"
                     /locus_tag="VQU19_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HET2480130.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASIAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(29009..29092)
                     /gene="pep27"
                     /locus_tag="VQU19_000861"
     CDS             complement(29009..29092)
                     /gene="pep27"
                     /locus_tag="VQU19_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198524447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HET2480131.1"
                     /translation="MRKEFHNVLSSGQLLADKRPARDYNRK"
     gene            complement(29272..30651)
                     /gene="vex3"
                     /locus_tag="VQU19_000862"
     CDS             complement(29272..30651)
                     /gene="vex3"
                     /locus_tag="VQU19_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HET2480132.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(30703..31350)
                     /gene="vex2"
                     /locus_tag="VQU19_000863"
     CDS             complement(30703..31350)
                     /gene="vex2"
                     /locus_tag="VQU19_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HET2480133.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQIDYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKDTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(31363..32640)
                     /locus_tag="VQU19_000864"
     CDS             complement(31363..32640)
                     /locus_tag="VQU19_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2480134.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNGITSYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
BASE COUNT         9241 a         7490 c         6082 g         9907 t
ORIGIN      
        1 ttaacgcatg tcgttcaagg taataatcca aacacgaaac cagtccacgt ttttcaagga
       61 ctggttttga tatagcacgt ttaagtaccg acttctgagc tactatagta gattgaaact
      121 agaatagtac atctcttctt ctaaaacatt gttagaaatc gatttggctg ccctgatcga
      181 ttcgtcctac tcttatttca ttttactata attgatagtg gtcgccccag ccagatacct
      241 tatccgctat ataggcctta ttatcatgtt cctgttcgta gagccacgat ttcgctatcc
      301 cttcctctga cgattcttat ttcctgcgtc agacttggga atcgctattg ggttcaccgg
      361 tagcaggtgc ccaccgagga cttacacctc agatatacga catgcccgtc gtacatcaaa
      421 aaaagttgag acatagcgtc ttcaactttt ttacattact ttaactactg attaaagtga
      481 gtttacgtca actttgatac caacaccttg agtagttgtg atagtcaagt ttgttacgta
      541 agttccttta gctgtagctg gttttgcttt ttggattgtt tcgttgaaag ctttaaagtt
      601 ttcaaccaat ttttcagctt caaatgatac tttaccgatg attgcttgaa cgttacctgc
      661 acggtcagca cggtaagtga ttttaccacc tttagactct tcaactgctt tagcaacatc
      721 cattgttaca gtaccagttt tagggtttgg catcaagtta cgtggtccaa ggacacgtcc
      781 aagacgtcca acaagaccca tcatatcagg tgtagcgata actacgtcga agtccaacca
      841 accgtcgttg attttagcaa caaggtcatc ttcaccaaca aagtctgcac cagcagcttt
      901 tgcttcttca gcttttgcac cacgtgcgaa aacaagaacg cgtgaagttt taccagtacc
      961 gtttggcaat accattgctc cacggatttg ttgatcagct tttttaacgt cgatgttcaa
     1021 gttgtaagca acttctacag ttgcgtcaaa ttttgcaaag tttgtttctt ttgcaagtgc
     1081 tacagcttct tctacgctgt atgcttttgt gctgtcgatt ttctcaagag cagcacgaag
     1141 ttgtttgctt tttttagcca ttttctattc tccttgtaag tggttcaatc gattttcatc
     1201 tcccacgtca cttctcgaaa tgatgaagtc ttgcgggttt tcagtctatt agattctttt
     1261 cctacggcct taagctccct tgctgtaccc aagtacaagc atcagtcact tgcctagtat
     1321 gaaaagcaac taatagactg ctgtgagatt ttctactgtg ttattgatta gtcaataaca
     1381 gtgaatccca tagaacgagc agtaccttcg atcatacgca ctgcagactc tacgtttgct
     1441 gcgttcaaat ctggcatctt agtttctgca atttcttgta cttgtgcacg agtaactgta
     1501 gcaactttag ttttattagg tgtacctgat cctttttcaa cacctgcagc ttttttcaaa
     1561 agaacagcag ctggtggtgt tttcgtaacg aaagtaaatg atttatcttc gtaaactgag
     1621 ataacaactg gaatgatcat accagcttgg tcagctgtac gagcgttgaa ctcttttgtg
     1681 aatcccatga tgttgatacc agcttgacca agagcaggtc caaccggtgg agctggtgta
     1741 gctttaccag cagggatttg caattttaca agtttttcga cttttttagc catttttaaa
     1801 tcctcctttg tggttttggc ggtaattaga gatttttacc tcccacaagt atgtttttca
     1861 catacccatc tattatacac tatttatctg gaattgcaag agaaaagttt attttttaat
     1921 cgacgtaatc tccaccttca aagccgaaat actcttccaa actgaggcca ctagctgcaa
     1981 tctctttagc ctcttttccg acataacgaa ggtgccattc ctcagccata tagcctgttt
     2041 ccttttcctt acctttgaga taacgtacaa caaagccata atcagccgca tgatccaaga
     2101 gccattgggc cgctttttct tctgtcacca aatcaccatt tgtcccaatc acatcaaagg
     2161 ctaaacctgt ctggtgctcg ctatagccag gacgggcaga ataacggtcg gcagcttctt
     2221 tcccatcttg attgacataa tcttgataga gcttggtctg agtttcataa cttctaaagc
     2281 cactgtaatg atcgctaatg gggaaacctg cctcttgcat agctttgatg agcttgacca
     2341 actcagcctt ggctgttgga ttttcccctg gattgtagtc ttttgacaat ggatagtgtt
     2401 tgttggctac gatgatttca tcgtatttcc cttgaatgct gtaatagtct cctttgttaa
     2461 ccacttctgc ttttttctgg gcagctcctt gagacttact tcctactgtt ccatcagctt
     2521 tagcagtttg ctctgtctta gctgctccat cttcattttt tgctttttct tgtgaacaag
     2581 ctgctagact caaggctagc aaggctgtca agacaaggta tctttttttc atctttactc
     2641 ctttatttct aatagtttat ctacttctga tgataaacgt tcgactaatc ttttaatctc
     2701 atcaggtttt gattggcaga tttctgctgt catttcttca aagggaatcc accatactgg
     2761 accacgtcca ttgaggccat aaccattcat atcacctctt cgtctaggaa acagatgcca
     2821 atggagatga gcatcgccat ttcctagtag ttcgatattc attttctcag cagcaaaggc
     2881 cttggcaact gcctcttgga ccacactcat ttcttctaga aaacgtattc tagttttctt
     2941 ttctaaatga tgcaattcgc tgacatgttc cttggctaga aagagactat agcctgcaaa
     3001 atactggtgg tctccaatca caagatagcc tgtttccaac tctttgacaa aatagggatt
     3061 ttctcccttc ttgatgagct caattctctg gcaaatcaaa cacatattag tctaccaatg
     3121 cactcttaag ataggcatcg accattcgtt ctgttgcgac caccgagtca atatgagtgc
     3181 gctcataaga atgactagac tcgatacccg caccaagaag ggcatgcttg acctctgccc
     3241 ctgcagacat agccgctgaa gcatccgaac cataaaatgg atagatgtcc agcttaaaag
     3301 gaatatcttg ctctttagcc aaggcaacca agtgttgacg gaagtcatag tgataaggac
     3361 ctgaggcatc cttgacacag atagatactg tgtactcatt tgtctgctgg tcatctccca
     3421 tagctcccat atccacagcc agatattcta ctacctgagc aggaatgtta gaattagcac
     3481 catgtcctac ttcttcaaaa actgaaaaag caaaatgagt tgttactggc aattcaatct
     3541 tctctttctt ataaatacga agcaggttga gcaacatcgc tgcgctgacc ttatcatcca
     3601 aatgacgaga cttgataaaa cctgtatcag tcacaacagt tcgtggatcg aagctgataa
     3661 aatcaccgac ctcaatccca agagcacgag tttctttttc attgcttact tttacatcca
     3721 aacgcacttc catattgtcc tgcgtgcgtt ctgcagttcc tgcatccttg tagacatggc
     3781 aagaagtttg gtggatgagg atggttccta ataccttttg acctgtgcta gccacatgaa
     3841 cggtacagtt ttcaccttca atcatgttcc aaggaaaacc accgatacgg tccaatttaa
     3901 gacgaccatc tggtttgaca gcacgaacaa tagcacccag tgtgtccaca tgggcagtca
     3961 catagcgatg ttgctcatca ttttgacctt tgatggtcac attgacacca cccttggctg
     4021 tgcgaactgg ctggtaacca aaaccttcta gagtcttgac taaataattc gaaatttcac
     4081 gagtgaagcc cgttggcgat gcgatggctg tcagttcttt gatatattct actgtttgat
     4141 tcatttcttc acctctttcg ctacctatta taacacattt atcatcggat aaaaaaagaa
     4201 aatcactcct gtagacttgg ctacaaaagt gatttaagtg attattccat ttcaaaaaca
     4261 tcgctttctt gcttgtttgg tagaaccaat gagagcaaga ttccaacaat ggctggcacc
     4321 aaccatggga gagatgcctt ggcaaaagga agaacgctaa caagatttgc aagaaactca
     4381 accttaaacg agcttcctag tacgcttgca atggcaataa ctgtaaccac agcaattgtc
     4441 aactgcatac ctggttttga aagggcaaca aatttgttga caatgacaat cataacgata
     4501 gcaatcgtga ttgggtacaa gataaccagt actggaattg agtacttgat aatcgcatca
     4561 agacccaaat tggcaatagc aaatccaatc aaggtaaagg ctgtcgcata aaccttgtag
     4621 ctgatttgtg ggaagcgctc attaaagaac tcagctgttg acacaatcaa accaacagtc
     4681 gttgtgaagc aggttacggt aaccatagct gcaaggaaga gttgagctgt tgagccaaag
     4741 atttcttgag tggcttgtga caagatgtaa acacctggtg ttccaccctt catcgcttca
     4801 gctggtactg ggaaatgatt tccaagaaaa cctaaaccga tgtaaagagc gctgaaggca
     4861 agggcaacaa cgataccaac aacccaaata gttgaaatgt attctttctt acttgaaaat
     4921 ccaagttgtt tcaaggtttg aactgcgatt acgctaaagg ccactgaggc aagggcgtcc
     4981 aaggtattat aaccttctag gaaacctgta ccaaaggcag aagcttgata agcagctgaa
     5041 gcagcttgag gacttgttcc accatatttg atagctccca gaacgaccaa gataacaatc
     5101 aaaattgcaa agactggcgt taaaatacgt ccaatgcggt ctaagatttt tgatggatta
     5161 agcgaaatca aataggctgc cgcaaaatac agaaccgtaa atacaatcaa gccaagtcct
     5221 ttatttgcat ccgacaaaag ggggctaatc cctacttcgt aagctgttgt agcagtacgt
     5281 ggggtagcaa agaatggacc gattgacaag taaagaactg agaggtaaag agtcgcaaac
     5341 caaggcgcta tcttcgttga aatctcgtag atatatcctt taggatttag cgttccaata
     5401 ataagggtca agacggcgat accaacgcct gaaaagacaa aacctgcgat ggcaggaaga
     5461 aaatgttctc cagatagagc acctagagaa ggcggaaaaa tcaagttccc cgcaccaaaa
     5521 aatattccaa acaggagcaa acctgttagg gtaccttttt tagccataaa aatctccttc
     5581 atatttataa aatactgatc tagtatacca cgattaggag tctgaaaaaa gcatcacgag
     5641 gcaaatatta aatgttttca attttcttaa aaataagaat tatctaaaaa taaaactctc
     5701 ctacccagtc cacaccaagt aggagaaatg caaaatttta aagttcttca aaggctaaca
     5761 tgccaccctg gacattgata acattataac cttgttctaa taggaattgg caagcacgcg
     5821 ccgatctcat tccagatttg caaataatat aatgcaagcg atctttgtcc aattaatcat
     5881 aactatcagc caattgacta agcggtaggt tgtgggcacc ttctaaatga agagctgcaa
     5941 actcatccac ttctctcaca tccactagag aaagctggtc gttttggtaa agctggtaaa
     6001 atgcgtcaaa ggctatttct ttcattcttt ttcttctaat actcttcgaa aatctcttca
     6061 aaccacgtca gcgtcgcctt accgtgcgta tgttaccgac ttcgtcagtt ttatctgcaa
     6121 cttcaaagct gtactttgag cagcctacga ctagcttcct agtttgctct ttgattttca
     6181 ttgactataa aatggtttta attctttttt tcaaatctgg cactacttct gcctcaaacc
     6241 aaggattttt ggccatccag atttgatttc gtggtgatgg gtgaactagc ggaaaatagg
     6301 ctggcagata gtctttatag tgtttcaccc tctccgttac cttcccactg attttctcct
     6361 gtaaatagta ggcttgggca tattgcccaa tcaagagggt taactgaata tcaggcaatt
     6421 cctgtaagag ctgcggatgc catttttctg caaaacctgt acaaggcgga agatcacccg
     6481 acttgccatg tcctggaaag tagaaatcca taggcaaaac agcaaaataa cctgaattgt
     6541 aaaaggtatc ttcatccaca cctagccagt cccgcaaacg gtcaccactt ttatctttcc
     6601 agtaaaggcc tgcttcttga gttttaagtc ccggagcctg accgatgata ttgatgcgag
     6661 cagtttttgg cgctgcaaag agaggctcaa tgccacgctc tgtatagctg gcattctgcg
     6721 aatccgccat gatagcctgt ttgattcttt cgatttgaga catctacttt ccctccaaaa
     6781 agaagtccaa gcataagatc tcagacttct atcgttttat ttgatcaatt cgtaaatagc
     6841 ttcggcataa attgctgctg ctcggaagag atcgtccaag gcaataaatt cattggcttg
     6901 gtgcatggta tcaattgagt ctgggaacat agcaccatag gcaactccgc gctctaacaa
     6961 gcgaccaaag gttccaccac cgatgacttg ttcatgacct ttaaggcctg tttgtttttc
     7021 atagacattc aacaaggttt gcacaagtgg atcttccatt ggcacatagt gaggggtatg
     7081 accatgttct gatagactga cagaagcaac tggcaagttt tctaggattg acttgatttg
     7141 ttctggactt gttccttttg gatagcggat gttaagggca atggtattat cagcacttgt
     7201 ttcatcgaag cggaagacgc cggcattcat agaaagagca cccatctttt catccacatg
     7261 agcaatcttg agattttcac cctcatgatc gttcaagaga attttacctg cgatgtcaag
     7321 gtagtctttg gctggaccag caaagccaaa ctggctgagg aagagggcaa ggtaagttgc
     7381 gccattgaca cctgaagcag gcatagcacc gtgggctgat ttaccaatga tcgtcacctt
     7441 gtattggcca gcttcttctt ggagttctcc tctaagtttg tgttctgcaa caaaggcatc
     7501 tagtttagct tgcaagtctg tcaagtcacc tgaaacgact gctgttgctg attctggtac
     7561 catattttca cgtaaaccac ctgtaaagct gtgaagacgg gctgcacctg tattttcacc
     7621 tgcaaagtgg aggtattccg tgatgtttcc tttttcacca ttgatgattg gaaattcagc
     7681 atctggtgag aaaccaaagt ctggcttggc gagtcctacg tgctcgaagt agtagtccat
     7741 atctgcccag cctgattctt cgtctgttcc aacgatgaag cgaactttct tagaagttgg
     7801 aaggcccaat tctttgatga ttttcaaacc atagtagcaa gctgttgtag gtcccttgtc
     7861 atctgaagca ccacgcgcat aaaggcgacc atctttgata gttggtgtgt aagggtctgt
     7921 gtcccaaccg ctaccagctg gaaccacgtc catatgggca aagattccga gaacttcttc
     7981 tccatcacca aactcaaaat gtcctgcata gttatcaaca tttttagttg gataaccatc
     8041 acggtctgcg atttcaagga atttttccaa ggcttttact ggaccaggtc caaatggatg
     8101 ttgggcatca gccttgctat catcacgttc tgagttgatt tccaaaaggc taaacaagtc
     8161 agccaagagg tcttctttgc gtttttctac ttctgctgta aaatcaattg ctatcatttt
     8221 ttcttcttcc tatctttttt cgatgatttc atctactggc aagcggtagc ttggttccaa
     8281 tttgtcgtct gtgtaaccca ctgtgatcaa gagttctggg cggaaacggt cttcaatttc
     8341 caaaacctca ttgacttttg atttgtcaaa accaaggata atattggaac caattccttg
     8401 gtctgtaaga gcgagaacca agttcatagc aaccaaacct gcattgagtg ctaggtagtc
     8461 gctgacttgt tgttcattgt agcgtgcaaa ttcagctggc aaatttttca tgaagtattg
     8521 aagttgttct tctgagaaat tgttagcacc accaactcgg gcaatcttac gagcgcgttt
     8581 ggcaaggtct gtatctgtaa atagggcaat ggttacaggt gctgatgata cctgctcaaa
     8641 gtttgaacca taagccaact ttgccagttc agcatttttc tcacgaacaa ctacaaattt
     8701 ccaaggctgg ctgttgtggg cgcttggcgc caaggttgca atttcgatag ccgtacgcac
     8761 atcttttaga tcaacaggct tatcagtgaa atgcttggtc gcatgacgtt ttttatttaa
     8821 ttcaagaaat ttcataatcg atttcctttt ctaattctac tgcttccatt ctaccataat
     8881 ttgaaagagc ttgcagggat ttttcatgat taagtttttc tatcacagac ataaaagata
     8941 tatattggtt tatcaggaaa gtttctgata aactagcaag tactttacat ttgaatggag
     9001 acagtatgaa aaaatttagc ctattactag ctatcctacc atttttggtt gcctgtggga
     9061 atcaagctac acccaaagag actagcgctc aaaagacaat cgtccttgct acagctggcg
     9121 acgtgccacc atttgactac gaagataaag gcaatctgac aggcttcgat atcgaagttc
     9181 taaaggcagt agatgaaaaa ctcagcgact acgagattca atttcaaaga accgcctggg
     9241 aaagtatctt cccaggactt gattctggtc actatcaggc tgcggccaat aatttgagtt
     9301 acacaaaaga gcgtgctgaa aaataccttt actcgcttcc gatttccaac aatcccctcg
     9361 tccttgtcag caacaagaaa aatcctttga cttctcttga ccagatcgct ggtaaaacaa
     9421 cacaagagga taccggaact tctaacgctc aattcatcaa taactggaat cagaaacaca
     9481 ctgataatcc cgctacaatt aatttttctg gtgaggatat tggtaaacga atcctagacc
     9541 ttgctaacgg agagtttgat ttcctagttt ttgacaaggt atccgttcaa aagattatca
     9601 aggaccgtgg tttagacctc tcagtcgttg atttaccttc tgcagatagc cccagcaatt
     9661 atatcatttt ctcaagcgac caaaaagagt ttaaagagca atttgataaa gcactcaaag
     9721 aactctatca agacggaacc cttgaaaaac tcagcaatac ctatctaggt ggttcttacc
     9781 tcccagatca atctcagtta caataacact cttcgaaaat ctcttcaaac cacgtcagct
     9841 ttatctgcaa cctcaaagct gtgctttgag caacctacgg ctagcttcct agtttgctct
     9901 ttgattttca ttgagtataa gatatactaa aagcgattgg accagccaat cgctttttta
     9961 gtttgcattg gctattttag gaaactctta caaaaaatca aaaaaattct tcacatcctc
    10021 tacataccca tgcttttcta ttaagctggc taaaagttcc agattgtgcc cctgatagtt
    10081 atcgtcacga cgcagttctt catacatttc aataaaggga agccccttgg acttggccaa
    10141 ttctaactca gcctcgtaat cataagcaac tttacgaaat tggatattga ccaattcccc
    10201 atcttcaact tctatcacgg catactgggc acggtgattt tttaacgcct cccaattaaa
    10261 atagggcatg ccaatcgacc ctggattgat gatttgttgc ccttgacttc cataacgaag
    10321 caactgcttg tgaacatgac cataaactgc cacgtccgtt tccgcatcta gcagttggtc
    10381 aaatttctct gtatcattct caactagcaa gtcaccacca tagttcttat ttggcaaatt
    10441 atgagagata gaaaagcgca gtccagcaat ttctttcttt tccagcaaag gcaagcttcg
    10501 tagccagaca gtcgttgcag gatccattcg ctccatcaaa aactgagtca ttcgcatgag
    10561 ctggatttcc tgtgggtctt ctaagccata ttgcccatct aaagcctcaa ggacacaatc
    10621 attccaattg cctcgaacac ttgccgtgat aggaagttcc tttaacagag cgaccaagtc
    10681 atttgcacct gaaccaggga ggaaaatgtc tcccatgagc caatattcac tggctccttg
    10741 agttttagca tctgcaatca ctgcttctag cgccgtcgca ttgccatgaa tatctgataa
    10801 aattgcgatt ttatggttta ttgtggtttc cttccgtttg gtaatctact ctttcttccg
    10861 ccacttgaag caagatttct gtttcctgcg ggttcaactt tctttgcaca gcctctgcta
    10921 ctgctcttgg tactccaact tcgacaatct catccacact ggcttccttg attttggtca
    10981 gagacttgaa gtgcctcatg agattttgct tgcgtttagg tcccagacca tcaatcccat
    11041 ccaattgaga tgagaaagaa tttttggagc gcagttggcg gtggaaggta atggcaaagc
    11101 ggtggacctc atcttgaatg cgttggagga ggaaaaattc ctgagaattg cgagacaagt
    11161 ccaccacttc cagcggatct ccaaagagca attcatgggt ttggtgctta tcattctttt
    11221 gcagacctgc aattggaata tccaagccca gttcttcttg gatgacttgc ttagcaatat
    11281 tgacttgacc ttgcccccca tcaatcacaa tcaaatctgg aggagtcaaa gcctcacgct
    11341 gtactcgacc atagcgtctt cgaatgactt ctctcatact agcatagtcg tccggcccaa
    11401 caacggtttt tatcttgtac ttacggtaat cttttttact tggcctgccg ttaacaaaga
    11461 ccaccatggc tgaaacagga ctggtcccca tgatgttgga gttatcgaag gactcgatgc
    11521 gaactggagt cggaatttgg agcaaacgtc ctagattttc aatagctcct tgggtctttt
    11581 cgactgattt ttctagcagg ttaaatttct gctccagact aacacgtgca ttttttatgg
    11641 ctagattgac cagctgtttt ttctctccac gttggggttt gagaatcttg gtatccacca
    11701 aagccttgac agcttcttcg tcaatatcct gcggaatcag tacctcattg ggaactaggt
    11761 gagatttttc ttgatagaat tgtcccacat aggtcaagaa atcctcatct ggatcattga
    11821 agtaggggaa gagattgaca tcgcgctcga tgagcttgcc ctgacgaaca aagaaaacct
    11881 gcacacacat ccagccctta tccacatagt agccaaagac atcgcgattt tggagatcct
    11941 tagccatgac ccgttgcttg gttcgaagcg ttccaatagc ctgaatcagg tcacggtatt
    12001 ccgccgcacg ttcaaactcc atactttgtg ctgctactgc cattttactc ttgagatcat
    12061 cgatgatttt gtcatcctga cctttcagaa aatcagacac ctcctgagcc atagacttga
    12121 aataagcctc atccttctta cagatggtgt gggccataca ctggccgata tggtaataaa
    12181 aacagacctt agagggcggg ttggtacatt ttcgaaaagg gaaaatccta tctagaagtc
    12241 gcttgatttc attggctgcc cccacatctg gataagggcc aaaataaaga ccaccgtcct
    12301 ttttgacctg acgagtaatg ataagccgtg gatagcgctc attggtgatt ttgatgaaag
    12361 gataggactt gtcatccttg agcatgatat tgtacttggg cttattttcc ttgatcaagt
    12421 tgatttccag cagaagcgcc tcaatattgg actcagtgac gataaattca aaatccacaa
    12481 tttcagacac cagagcctct gtcttggtat catgaattcc acgaaaatag gaccgtactc
    12541 gattacgcag atttttagcc tttcctacat agataatggt gccattttta tccttatgaa
    12601 tgtagcaacc agggctggtc ggcaagagct ctagttttga tttaatcaag ttgttcatag
    12661 ttccattata gcaaaaaaag tagggaaaga tagtacccta ctcactagtc tcatatattt
    12721 ttcggaggtt tgcaacatcc tcttcctgga taccataaaa ggaacctgct ggttgcatga
    12781 cagacttctc atctgtatgg tccaagccaa tcgcatgacc taactcatgt tctgccgtat
    12841 ggacaaggcg ttcataggag tagccatagt atggattgga caaataataa tgattcaacc
    12901 gcaccgttac ggacaagaat tgccctgtta agagattagt ttgactttcc gcctctcctg
    12961 ccacaggagt gcctccgtcg ttcatctccg tagccgtaat atccgcctta ctagactcag
    13021 tcacgagttc aaagttaaaa gcaccagttt gattccagtt ctggattgct tctaaataag
    13081 cctcttgaaa gcgtgaatcc atctgcggat ccaggtaaat acgagcagag gcctgtgccc
    13141 accttccttc agaatgctgg tgactatctg tctggcttaa cttaggcagt tgccctgttt
    13201 tctcccattg gtcaatactt tgttgaccca tttttactga ccgttctgct tgctttagcg
    13261 ctccttgaaa atccccgttc agataccaga gaagtccgaa agcaagcaca cataagagca
    13321 caactatcca aaccagacgc caaaacaaac gccacacaaa agaaaagaaa gcccctatca
    13381 aacgaaaaag ccagcgcatg tctctccacc tttctagcaa ataagaatta ttttactaaa
    13441 agaagctaaa agaaatctaa atactgactt tttcatctta acgtcctact atttttttga
    13501 gtaactggat agctttgtat tttaaaggcg atggatggta acggaaagta cctgctttgc
    13561 gtacaatata gccattaaaa ttctgtttaa aacgcaaaac accatcactt ccatcaaaaa
    13621 tcccttgaat gcctaggaag ttgtatttag gtattccacg ttttatgctt tccaacataa
    13681 catatttttg aagcagtgca ggggcataga acttattaaa ctcagtgtag gaaccactaa
    13741 agagataagt cgtttcctga ggcatataaa caaataaact cccagctaaa acaatatctt
    13801 cttctccata tttttcaatc aagtctcgcg cttctgcttt tcgaacttca aacgtttcaa
    13861 attgactaga atattctctc agttgatttt gttttttctc agaatgagga tttttactca
    13921 aatcaagtcg caacttgtcc aagttttctt ctagtttact ttgttcacct tgcaatttgc
    13981 tcatatactc cgaaaaattc aagcttgcta tgagaaactc cgcttgttct ccaaaagtat
    14041 cataaaaatg ctcataatat tctaaacttt tatcactata ttctctacgt tcagaggttt
    14101 cttttgttat attcttaaaa atcgatagtt cttcacgttt taactttttc aaccgaatgc
    14161 caaaggtttc agcctttttc accaagggtt tacccttttt gctaaaactt ttaagcaaac
    14221 tcttttcagt taattcagtt aaatctttat agtataacca atctggttct ccacctgggt
    14281 aacctgttgt taagccatca aattgataac ctaaatcagt caaaccttga ataatacttt
    14341 ttttctcagc atctattgga ttaccttggc tatcaaaagt ttgataagtt tcataaggtt
    14401 ttacaagcaa ctctaataca ccattttgct tggcatattc ttttaactct gcataaaaaa
    14461 ctggaagagc atcttgttgg gtataaatcg gccccgaatt gagttccata tgcagaccac
    14521 ccagcatggg caagctataa accagagctg caacttgaat ttctccttct tgtttcaaag
    14581 caagataaac aattcgagcc cctctttttt ctagcaaatc ccccatctgg acagattgca
    14641 taaaggaacg agaagaaacc tgatcagaat aagtctgaaa ctcttctttc gtgagtgttg
    14701 ttagtgccat atacttactt tctatgtttt tttcttaatg ttttacggaa atcaagagca
    14761 agtcttaaca gaggatagag aggatgagtg ggcattgtaa attcacccaa gtattcttca
    14821 atcgttggat taaatttttc cttaaaatga taaagtccac cattgagaga gttttcaaca
    14881 ccacctaaat tttgccagac catacctcgc tcaaaggcat agcgagccgt ttcataccat
    14941 gttaaaattg gtgcattgta acgtttaaaa tcatcatcca taccagcata tatattgaca
    15001 gaggtagtac caaattccaa actcaaagta gccgctaaag gaactctcgc ttgacctaca
    15061 tctatatatt cctgcaagaa ggtcaattcc tctaacaaac gttctttttc cttcttctgc
    15121 gcttctactt ttgaagttcg agtcgactca gtaaaggtct cttccaaggc tctatttttc
    15181 gctaactgtt cttctaactc ttgcgaacgt ttagaaacat ccaaggtggc caaggtgata
    15241 taggccttgt ccttaaaatt atctaacaat tttttataat aggcttcatt cctcaaatga
    15301 atctcttttc gcttctcagt ttttttcatc aactccgaaa atgaatctaa tagttccagt
    15361 ccaccatatt gaatctcaag ccctttgttt cgtgctgttc gaatagcctg ttttgttgac
    15421 ttggaaagtt tatcttcttc aaaattttcc ttgtatattt tcgcctgaat acgaggttga
    15481 atggtgtctc ccatttcctc cgtttttcct gaccacctta ctcccatttg ttgcaaacta
    15541 tcaataatag ccagattttc aggaaattct gtcttttcct gattgattaa actttgagat
    15601 aggcaaatac ttgggtcaaa agtcacaaaa accgctctct tactgcgagc ataggactta
    15661 atagactgaa tggcaaaatt caagagttct ttatccccat aatccaatat aggtcctctt
    15721 gggatgtaaa acattttata gcctagcgga agagttctaa tcaaaatact agctgtcgcc
    15781 agtaattttt cttccctgta aacaccaaac ttctcatgtt gccaattaga cttaacttcc
    15841 tcccaagcac tactttgtaa tacattggct aattcatgtt ctttgacaaa ctgatcatat
    15901 tctaatgtgg gaatgccaat ttgataacgg tacatttcct actctctttc ctccagtatt
    15961 ttattactat tctactactt tcgtttgaaa agtctagtga aaacatattt tattttagtt
    16021 ctactccccc tatgctgaag ttcaaactaa gtcagtctct cttctaattt gaaatcaatt
    16081 ggtagggttg ttaaaaaaac ttccaattgt ttttcccagt agtaccactc gtgagttcca
    16141 gcgctatggc tataggtcac atcaaaacct agttttttga gatttttcac tgcgagatta
    16201 ttggcttcgt acaagaaatc ctgttcgcca caccacgccc aaagtttggt ctttttatcc
    16261 gattttttag ccagactttc aagagaatag ggactagttg tccagtctct aatctctcca
    16321 aaaacacctc tccagtaggc tggacttccc agattttgac tttcaggaga aaagttttga
    16381 aagctgaggg cacctgaaaa actagctgca tgagaaaaac gatttgtcgc aagagccagt
    16441 ttgaagcagc cgtaacctcc catagaaaga ccagcgataa aggtcttttc acgcttgcta
    16501 gtcatattag ggaagaagcg tttcagaacc tgtggcaatt cctctgctag agccgtgtag
    16561 tagtcaaaac catactgggt atcggtgtac caaccattgc tggtattggg cataacaacg
    16621 atgagattag ttcctcgaag caagcgttct acattggtcc gcttaagcca actattatga
    16681 tttccagaca tcccgtgcaa aaggtacaag acgggaatat cttcacactc tggttcttcc
    16741 actcgattgg catcagggta gaggacattc accccccact ccatatccaa tacttgtgag
    16801 taatactcga ttttcattac tgccatgatt ttctccttct atttttctat aagaaaaagc
    16861 cgaaactcga ctttctctct gtttatttca acgattattt tgcttccatg actactggta
    16921 aaatagctgg acgacgcttg gtttggtcaa agagatactt ggtcaaatta tctcgaacct
    16981 tccctttaag atctgcccag tcaaagtcat ctccttgaag ataatcttct accgtttggt
    17041 taatcaattc tgaactttca cggagaatat cgcgactctt cttgagataa acaaatccgc
    17101 gcgtatgaac acgagcccta gccacaattt tcttctcacg acggttgact gtaatagcca
    17161 cgatgaaaat tccatcctct gacaagatct tacggtcacg aagaacaaca tttccaacat
    17221 caccaatggc attcccatca atcaagatat ctcctgctga aaccgatcca gctggaacaa
    17281 agtctccatt ctcgtaagcc atggtcgtcc cctttttagg aatgaagatg tgttctggca
    17341 acatcccaac tgccatggca gccttagcgt gagcatccaa ctcacgatac tccccttgga
    17401 cagggaagag gtacttaggt tgcaaaagat tgatcatcag ctgcaaatca cgcacatttc
    17461 cgtgccctga tacatgtaaa ctttgggtaa tcaatttgac aaccccacct gcctgataaa
    17521 tcatattttc cacacgcgca acaaaggctt ctttagcaat agacggagcc gtagcaatat
    17581 agaccaggtc cccatccttg atttctacat aacgatggcg accaatcgac atcttacgaa
    17641 gtccattgat aggttcaccc atacgacctg tctcaagaat aatcaactca tggtcttcaa
    17701 agcgagacat atctttaggc ttaatcaaga gaatttcgtt ggctaaagac aacttcttaa
    17761 gacgaatcgc tgtgcggacg atattttcaa tatcaaatcc tgtcaagacg atacgtcgac
    17821 ctgttttatc cgcagcgtca aaaatctgct gaatacgaga aagattactg gaaacagctg
    17881 caacgatgat acgaccttcc cagtcagcaa tagtttgggt aatttcatcc ctaacttcac
    17941 tttcactagc cacctgaata ttgctgtctg cattggccga atcactgagg agagccagga
    18001 cgccgtcacg accaatctct gccaaacgag caaaatcagt tgcataagat tcactagccg
    18061 tttggtcaaa tttgaagtca cctgtataaa cgatgcttcc ttccgatgtc ttcaagacaa
    18121 ttcccagact ctctggaacg gagtaagtcg tagggaagaa ggaaaccact gtcccaccaa
    18181 aatcaatctc cgtattctca tcaatgacat ggaaatcatt aaatttctta acggcatcat
    18241 ttcctttgac aaagagcttt gccaactcaa tggtcaactc agacccaaat acaggaactt
    18301 tagcctctgc caagagataa ggtagagcac caatggcatc cgcatgcccg tgggtcaaga
    18361 aaaccccagc aatacggtcg ctattttcaa aaaggtaatc catgtttgga atcaccacat
    18421 cgacccctaa ttgttcattt tcaggatatt ttaaccctac attcaaaaca aaaatggact
    18481 ctccaatttc agcaatgtac atattttttc cattctcacg cacaccacca agtgttgtta
    18541 aactgatatt actcattttt cctccaaaat cttagtttat cttgattata gggcaattct
    18601 accctcttat tctaaaagtt ctgatacttt cagccgaatc ttttcctacc attataccat
    18661 ttttttgatg attttcaaaa tgaaggtctg ttttcaaaaa agagttgatt tcccaactct
    18721 ttcctaactt ctactctttt tccatcaaaa aatcataaat ttcttgcacc gtacccagcg
    18781 ccatcatttc ttggtcttta acggtttgtt tgagattttg gtaaatttga ctttctccta
    18841 tctcccgctt tggcgcctct ttattgactg tcatcacacc atcttttatc gtcacaaagc
    18901 ctagttcttc aaatacttga atcatcttga ccagcaagat ttgttgaata ttaagatatg
    18961 cagccaaatc tttcagcttg tagcgaatat caaactctgg gaactggtaa atagtcttgt
    19021 acaatttagc aaactgatct ctagtcccat aacctgtcag ataataggtc ttgtcaatat
    19081 catttttgaa atagacagca gagaaatgct gttcctgaaa aatggtcttc agctgagtaa
    19141 tatcctctgg aatgtttttt acgacaacag cttcactagc cgcaagattt ggcagttctc
    19201 caggaaaatc caagactgga acaccttctg gcaagactgc attttttcca cgaatgttaa
    19261 aaagttgaac accttccact cgcgcatcca ccatcatcaa ctggagggca gtttggccat
    19321 tccattggtt gacagacaat ttaaccgcta actctagatt cttggtttga gaaaactctg
    19381 tcgcccatct gccttgacca aaggctacca cttcaaaact cgcctcaccc ttggaaattt
    19441 tcagctttag atgggcatta cctgccccca tagtacgagc actttcgacc tgaaaattct
    19501 tgatataaaa aataggtttc tgattatcca ttccaaaagg agctaaacgt tcaaaacttt
    19561 tgaccgtttc caagctaagt gcctccaaat ccaactcttc atctaggttt aacttattct
    19621 tgccaccagc atctgcacct ttttcacgaa cataatcttc caaaacctga gataaatctg
    19681 agagttgctc aacttccagc gtcatacccg ctgcacctgc atgacctcca aaggcgatga
    19741 agaggtctcg atggggatcc agagcttcaa aaatatcgac cgcttccaca ctacgagcac
    19801 tgcccttggc acgaccgtct tctatattaa gaacaatgac tgtctgtccc aattcttcca
    19861 ataaacgacc agccacgatt cctagaaccc caggattcca gccttccttg gccaagacct
    19921 gaaccttctt ctcaggatcc accatggtct tggcttcttc atagatagac tgaacgattt
    19981 ccttgcgctc ttcgtttttc tggtgaatca taagggcaat ctcatgcgct tcctcatcat
    20041 caaatccagt caacaaatca atggcaggat tgggatcatc caagcggccc aaggcattca
    20101 aacgaggagc aatctggaaa ccaaccgttt cttctgttac ttcgttggca gcaatcccag
    20161 ccatgtccag catttcttgc agaccaatgc gctgggtatg acccaacatt tccagaccat
    20221 attgaactaa gatacgattt tcatccgtca gactcaccat atctgcaata gttccaatag
    20281 cgaccaaatc aagcaattcc acttgcactt cttctaacag ggcacaagcc aacttgaaag
    20341 caactccaca accagccaaa tatttaaaag gataatccgc atctggatgt tcaggatgga
    20401 caatagcata agcatctggc agggtttcag gcatggaatg atggtctgtc acaatgacat
    20461 ctactcccat agactgagcc aatgcaatag cctcatgacc agcaacccca ttgtccaccg
    20521 tcacaatcaa ggaaattcct tcttgctcga taaagtattt ataaacacta gcattagggc
    20581 catagccatc ggtaaaacga tttggcaggt aaactcggca ctcagcacca agttgttcca
    20641 aactttcctt cacaatagaa gccgaagtca tgccatccgc atcatagtct ccataaacga
    20701 gaatattttc cccttcttca atagcctgac gaatccgctc cactgccttg tccatatcat
    20761 ggagcagata agcatcatgt aagtcctcca aggaaggttc taaaaacttc ttcagacttt
    20821 cttggtcctg aatccctctc tcaaacaata accgagccac ctcaggaccc agtccagcct
    20881 tcttggctat ctttgtaaaa tccgcatctt ctacctgcag ggcaaactgc cattcataag
    20941 taggtgttat caaaaagaca tccactcttt ctaagaattc tattgcttca ttataacatg
    21001 atttagacgt tttctctatc cagattgctt ttttataaca ttttatagta tattgaaact
    21061 agaatagtac acctctactt ctaaaatatt gttagaaatc gatttgactg tcccgatcga
    21121 tttgtcctgt tcttatttca ctatagtgaa ttttttcaga tatggtttga caagaacatt
    21181 ctttcattgt agaatcgtgt tataaaatat aacacaaagg agatctctca tggctttagt
    21241 agaatttaaa aacgtcgaaa aatattacgg agactaccac gcactccgca acatcaatct
    21301 ccgttttgaa aaaggacaag ttgttgtcct gcttggacct tctggctctg ggaagtccac
    21361 tcttatccgt acgatcaatg gtttagaggc tgttgacaaa ggaagtctcc tagtcaatgg
    21421 gcaccaagtt gctggtgcca gccagaaaga tttggtacct cttcgcaagg aagtcggcat
    21481 ggtttttcaa cattttaacc tttatccaca caaaacggtg ttagaaaacg tgacacttgc
    21541 gcccattaaa gttctaggaa ttgataaaaa agaagctgaa aaaaccgccc aaaaatatct
    21601 ggaatttgta aatatgtgag acaagaaaga ttcctatccc gccatgctat ctggtggaca
    21661 aaaacagcgg atcgccatcg ctcgtggtct tgctatgcat ccggaactcc tcctctttga
    21721 tgaaccaaca tctgctcttg atcctgagac tatcggagat gttctagcag ttatgcagaa
    21781 actggcgcat gatgggatga acatgatcat cgttacccac gaaatgggct ttgctcgaga
    21841 ggttgcggac cgcattatct ttatggccga cggagaagtt ttagtagata cgacagatgt
    21901 cgataacttt tttgacaatc caagcgaacc tcgtgcccaa caattcctca gcaaaattat
    21961 caaccacgaa agtgacaaag tcaaataagg aggcgcctat gaaaaaaaat tctttttatc
    22021 agcattattg attagccttt tcggccttgc tgctgccaaa ccagtccagg ctgatactag
    22081 tatcgcagac attcaaaaaa gaggcgaact ggttgtcggt gtcaaacaag acgttcccaa
    22141 ttttggttac aaagatccca agaccggtac ttattctggt atcgaaaccg acttggccaa
    22201 gatggtagct gatgaactca aggtcaagat tcgctatgtg ccggttacag cacaaacccg
    22261 cggccccctt ctagacaatg aacaggtcga tatggatatc gcgaccttta ccatcacgga
    22321 cgaacgcaaa aaactctaca actttaccag tccctactac acagacgctt ctggattttt
    22381 ggtcaataaa tctgccaaaa tcaaaaagat tgaggaccta aacggcaaaa ccatcggagt
    22441 cgcccaaggt tctatcaccc aacgcctaat tactgaactg ggtaaaaaga aaggtctgaa
    22501 gtttaaattc gtcgaacttg gttcctaccc agaattgatt acttcccttc acgctcatcg
    22561 tatcgatgcc ttttccgttg accgctctat tctgtctggc tacactagta aacgcacaga
    22621 actactagat gatagtttca agccatctga ctacggtatt gttaccaaga aatcaaatac
    22681 agagctcaac gactatcttg ataacttggt tactaaatgg agcaaggatg gtagtttgca
    22741 gaaactttat gaccgttaca agctcaaacc atctagccat actgcagatt aaggaggaca
    22801 ccccatgata gatttatcat cttggacagc ctattttcag gattttggac aatttttcaa
    22861 tggtttcctc tttactcttg ccctagcgat tggatccttt atcctcgcca tggtcttagg
    22921 aatcttcttt ggtgccatgt caaccagtaa acgtccaatt ttacgcattt tagctcacat
    22981 ctttgtggaa ttttaccaaa acactcccct cttggtgcag tttgttattg ttttttatgg
    23041 cctacctctt atcagtgacc atactatcat gattccaatt tattggacag ctgttctctg
    23101 catgggactc tatcacggcg cttatatcgc tgaggttatt cgttcaggga ttcagtctat
    23161 tcctagtggt cagatggagg ccgccttgtc gcaaggtttt acctatatca gtgccatgcg
    23221 cttgattatc ttgcctcaga ccttccgcat cattctccct ccattgacca accaaattgt
    23281 taacctcatc aagaacacct ctactgtagc tatcatctct ggagtagact tgatgtttgt
    23341 gactaagtct tggtcggctc tcaacggaaa ctatatccca gcctttttag gtgctgctct
    23401 tctctacttt gctctatgct tccctgttgc ccagtttggt cgcaagatgg agcaagccaa
    23461 caaaaaagcc tattcacttt aggaggttac tatggaatct attttagaag ttttaacccc
    23521 agataaccta gtctttatct ttaaaggatt tggcttgacc ctctatattt ctctgattgc
    23581 catcatcctc tctactatca tcggtacggt gctagctgtc atgagaaatg gcaaaaatcc
    23641 tgtcttacgc attatttcca gtatttatat cgagtttgtg cgcaacgttc ccaaccttct
    23701 ctggattttt actatctttt tggtgttcaa aatgaaatcc acaccagcag gtattacagc
    23761 ctttactctc tttacatcag cagccttggc tgagattatt cgaggcggtc tcaataccgt
    23821 agacaaggga cagtacgaag caggaatgtc acaaggcttc acctcagccc aaatcctcta
    23881 ctacatcatt ctcccacaag ccatccgcaa aatgctacca gccatcattt ctcagtttgt
    23941 taccgtgatt aaggatacca gtctcctcta ctctgttatc gccctacaag aactctttgg
    24001 agccagccaa attctcatgg gccgttattt cgaaccagag caggtcttca gtctttgcat
    24061 cctgattgcc ctcatctact tcagctttaa cctagcaatt tctagcctgt ctcatatgct
    24121 agccaaacgt tggcaacaag ctgcagaata atactcttcg aaaatctctt caaaccacgt
    24181 cagcttcacc ttgccgtata tatgttactg acttcgtcag ttctatccac aacctcaaaa
    24241 cggtgttttg agcagcctgc ggctagcttc ctagtttgct ctttgatttt cattaagtat
    24301 aaacagccac tctccagttc aattggagag ttttttgatg agagtagata tttatagacc
    24361 tcaatttgac accatacatt ttctatgata aaatgtaaca aattcattta caacaaatcg
    24421 aaatctaaat gaaatggaat tttctatgaa atcagtcaaa ggactactct ttatcatagc
    24481 tagttttatc ttgactcttt tgacttggat gaacacttct ccccaattca tgattccagg
    24541 actagcttta acaagcctat ctctgacttt tatcctagcc actcgtctcc cactactaga
    24601 aagctggttt cacggtttgg agaaggtcta caccgtccac aaattcacag cctttctctc
    24661 catcatccta ctaatctttc ataactttag tatgggcggt ttgtggggct ctcgcttagc
    24721 tgctcagttt ggtaatcttg ccatctatat ctttgccagc atcatccttg tcgcctattt
    24781 aggcaaatac atccaatacg aagcttggcg atggattcac cgcctggttt acctagccta
    24841 tattttagga ctctttcaca tctacatgat aatgggcaat cgtctcctta catttaatct
    24901 tctaagtttt cttgttggta gctatgccct tttaggctta ctagctggtt tttatatcat
    24961 ttttctatat caaaagattt ccttccccta tctaggaaaa attacccatc tcaaacgctt
    25021 aaatcacgat actagagaaa ttcaaatcca tcttagcaga cctttcaact atcaatcagg
    25081 acaatttgcc tttctaaaga ttttccaaga aggctttgaa agtgctccgc atcccttttc
    25141 tatctcagga ggtcatggtc aaactcttta ctttactgtt aaaaattcag gcgaccatac
    25201 caataatatc tatgataatc ttcaagccgg cagcaaagta accctagaca gagcttacgg
    25261 acacatgatc atagaagaag gacgagaaaa tcaggtttgg attgctggag gtattgggat
    25321 cacccccttc atctcttaca tccgtgaaca tcctatttta gataaacagg ttcacttcta
    25381 ctatagcttc cgtggagatg aaaatgcagt ctacctagat ttactccgta actatgctca
    25441 gaaaaatcct aattttgaac tccatctaat cgacagtacg aaagacggct atcttaattt
    25501 tgaacaaaaa gaagtgcccg aacatgcaac cgtctatatg tgtggtccta tttctatgat
    25561 gaaggcactt gccaaacaga ttaagaaaca aaatccaaaa acagagctta tttacgaagg
    25621 attcaagttc aaataagtaa tcatactctc ctgggatttc ccaggagagt tttttatagc
    25681 caaatgaaat aaaaccggaa cgatggaatt ttggcattca aatcaattga taagaatatt
    25741 ttatagtgga gtgaaatagg atacgaacaa attgattagg aaaatcaaat gaatttatag
    25801 aaatctttta gcagttatgt tgtcctattc tagtttcaaa acgctataga agcagcattg
    25861 tgctagtcta gattcagttt actatactaa aacgagtagc ttgaaatcaa aaaacccacc
    25921 ctcacaggca ggttttatct gtattattca gctagattat gctttacctt ctgaaccgaa
    25981 tacgtcgata cgttcttcaa ccgatgcttg gatagctttt acaccgtcag ccaagaattt
    26041 acgtgggtcg aagagttttt tcttgtcgta ttctgcttcg tttgcttcgt agtcacgagc
    26101 aaatttacga gttgcgttag cgaatgcgat ttggcattct gtgttaacgt taactttggc
    26161 aacaccaagt ttgatagctg cttggatttg ctcatcagga atacctgatc caccgtgcaa
    26221 tacgattggg aatcctggaa gagcttctgt caatttttgc aagtggtcaa ggtcaagacc
    26281 ttcccagttt actgggtaag ggccgtggat gttaccgata ccagctgcca agaagtcgat
    26341 accagtttca accattgctt tagcgtcttc gattggagcc aattcacctt taccgatgat
    26401 tccgtcttct tcaccaccga tagtaccaac ttcagcttct actgagatac ctttagcgtg
    26461 tgctttttca acaacttctt tagccaattt aaggttttct tcaactggaa ggtgtgaacc
    26521 gtcaaacatg attgaagtat aaccaacttc gatacactca agtgcatctt cgtagtgacc
    26581 gtggtcaagg tggatagcta ctggtacagt gatacccatt gattcaacaa ggttagcgat
    26641 caagttgcga gcaactttgt aaccacccat gtatttagca gcacccattg aagtttggat
    26701 caaaactgga gcttttttag cttctgctgc gcgcaagata gcttgagtcc actcaaggtt
    26761 gtttgtgtta aatccaccaa ctgcataacc gttgtcacgg gctgcttgga caaatttttc
    26821 tgctgaaacg attgccattt tatcaggcct cctgtatatt tttatgggtc atcccattta
    26881 cattgttcat tttatcactt tttgccaaaa aaatctagtt tttcccgcag tttcgattga
    26941 ttttcttcta actccatcta tgtaaaccct ttctctccct agtcttggac gacttttgga
    27001 aaatctataa agaaggttaa acgattctcc tccatctcga aacgataagc taatttttca
    27061 tgttctaata gactcttaac cacaaagagc cccataccag accccttgac cttgcgactg
    27121 gcattgtcag aaaaagactg ggctagtttt tcttgttcct ctgagctaca gctattttcg
    27181 ataaaaagtt ctccttctct ttctccaatt cgaactaagc cacctggaac agagtgctta
    27241 atggcattgc tgatgagatt agaaagaatc aacttcataa ctgatgggtt tagataagcc
    27301 tgctgatggg tcaaactatt gtctatctgg agctctcttt ccttggctag caaggcataa
    27361 tctttgacca gattttgcgt catctggagg aggtcaattg tttccctatc atctcgcaat
    27421 tcctgcacag aagagaggga aagtatctgc agaacatggt gattgagttc atccacaatc
    27481 cccaaggcaa ctcccagata ctggtctcta tccttataac gaccgatatt ctctctcata
    27541 ttttcgatta ggattttcaa actagccagc ggtgttttca attcatgaga agctcctcgt
    27601 aggaattcga ccttcatctt ctccagctgg agaatggctt cattcttttc atgcaagtcc
    27661 gcaataacag tcaagagatg ctggtagagg ctattgattt gttccttgag attacctatc
    27721 tcatccttag aatccacgcg caatcgcact tgggaatcca ggtccatcat ccgacgggtc
    27781 acccgcttga tttccaagat cggtgcaaca atagtccgag cgtagatgta ggccaccaag
    27841 agggaaatca gaaaggaggc cagcaaggta tagggaagaa actggagact gatttgctcc
    27901 gcttcctttt gtaaatccat ggaagctaga aactggagaa tcatagtagc accgtcttgc
    27961 gttttcacct cgcgctcctc aataaagaga gaggttgtct ggcggtctgt gtccagagga
    28021 agactgtcct tgacttctaa cttgtcctcg gtcatctcac ctttgacggt ccccttgata
    28081 tcactagtct gggaatacaa gtctaacact tgctcgatac tctgcctatc tttcccttct
    28141 agggactggg caatggctgt tgccttttga ccaatggttt cctgacgatg actcagataa
    28201 gtcgaaggaa aaagaaaata aatagctaaa tgaaggcaga taaccagaac actaaatatc
    28261 gagaaggtat agataaatat ctttgcaaat aaacctgttc gtttcatttt cgctccaatt
    28321 tataaccaac attgcgcaca gtgaggatac aatccaagtc tagctttttc cgcaattcct
    28381 tgatataaac atcaataaca cggtcaaagg gaacctcatc tgtcgctttc cagacggcat
    28441 cgataatctg agatcgagtc aaggcccggc cttcattttt cactagatag tccagaattt
    28501 ccaactcttt ggcattgata ggcacttctt gacctgcgat gcttgcactg tagctttcaa
    28561 agtccacctt ggtatccttg taagaaaaga ttcgtcctgt atcgtagtag cgcttgaaaa
    28621 tcgcgtccac cctcactttt aaaagggaga gggagaaagg tttttccaga tagccatctg
    28681 ccaaagaggc aaaggcactc atcttgtatt cctcatcttg aaaagctgtc aacatcaaga
    28741 caggaacctg actggtttta cgaatctcag ctaggacttc taagccgttg agcttgggca
    28801 tctggatatc cagtaaaacc agggccacct catagctaga aaattgctcc agagcttcct
    28861 gaccgtccgc tgcctcaata gtttcatagc cacaatccgt caaataatca ctgaccccct
    28921 cacggatcat ctcttcatct tctacaatta aaattttcat actttaactg ctctctattt
    28981 tttatttttc ttagaataaa tacctactct attttctatt atagtctctt gctggccttt
    29041 tgtctgcaag caactgacca ctagataaaa cgttgtgaaa ttcctttctc ataaattcca
    29101 taactttagt atattatatt taagcactaa agtacaaaga aagcaactga aagcaatgat
    29161 tttcaccact gctttcggat ttattttgaa ttgttaaata gccattccta tccactattc
    29221 ttgaatagaa acacaagatg caatctttat tctagactca ttttttcaaa tttattcacc
    29281 atccagcaag agctcttttg gttgttttct aaggagattg cttgaagcaa gcgccataac
    29341 gagaaccact agaaccaagg caaggacaaa aatgatgata aagtctgatg tctgaatgga
    29401 aatgtctagg ctcgacaagg tcttgctaaa gccatctact tctgcaccac caccaaggtt
    29461 agaggcttga gccgccttac tagcctgttt ggcaacacct gaagtcacat tggcaaggac
    29521 agtgtttcca attgcacggg cagtgtaatt agctaggaag taagcagaaa ctagagcagg
    29581 gatagcaatc aagatagatt cggtgatgaa ttgacccaag atacttgcct gcttgaggcc
    29641 gatagagagg agaattccca cttccttgcg acgggcgttg atccaaaggc tgagcaagag
    29701 ggcaaggagg agaactgaga agctcaagct accccagaag aggaggttgg ccatcttgta
    29761 cataccagag atagattgct caagagctgg gtagttagag gagctcttga cgagtgtgta
    29821 gctcttccag ttgataccac tgatgccatt caactctttc ataacatcat ccaagttctt
    29881 gtctgctgtt acaaagaagg ttgcgtcccc ataaatggct gtgtcttctg tgtatccata
    29941 aagttttgca gcagtgtgaa tgtctgtaat agctgtgttt tcgtaaagtt cttgtgagta
    30001 ggttactgct gacttattat gaccatcaaa gagtcccttg attgtcactt caactgtttc
    30061 cttggctcct ttttcattat ctgcatcgta gatattagag tccagtttaa ccttgtcccc
    30121 tactttccag ccgtgtttgg ctgccaagtc cttgtgcaag aggattttat ccttgtcgtc
    30181 gttggttaag tgctctcctt cgactagttt ataagaacca gagacaaact tgtcttcttt
    30241 agaggagtca ttgacacctg taatcatcaa gctacttcca aaacgcttgg cacgatcagc
    30301 agtgagattc ttcttggttt ctggcgtttc aatcaggtca tatccagtca aatctccgat
    30361 agcgttgata cgtttgacat aagactcgat ggccttgttt tcggtgattt ttttgatgtc
    30421 ttcacccttg atattcccag caccacgagg cgttccttgg ttgacgcgac gattgatttg
    30481 catggagaag ctattagtga tatttttaaa ggtctcctga gaagccttgg cagtagctcc
    30541 cttgattgac aagccgacca aactcaagct cgccatgagg agaataatca ggaagatgac
    30601 aatcgatttg aaaaacttcc ttgtaacata ggcaaatgcg ttgtgtaaca tagattccct
    30661 ttctagattt tgttttaatc attctatcaa aataagctca aattatttac tagtattgcg
    30721 cgtttcagtc agtttcttat cctttaattc aagtgtaata tctgacgctt gtgccacttc
    30781 tttactgtga gttacgacaa tcacacattt acctgttttc tgggcaagtg atttgagtag
    30841 ttcgacaata tctccagcag ttttaggatc cagatttcct gttggctcat cagctagaat
    30901 aactggagct tctgagacca aactgcgagc aatggcaaca cgttgctgtt gaccacctga
    30961 taactggaga acattccgct tgatctggct ttcatccaaa ccaagctcaa gaagtgtatc
    31021 cttgcttgcc tttttgttga ccaagcggat attttccagc ggagaaagat aatctatcaa
    31081 gttataattt tgaaagacca gggaaatatg gtgcatgcga tggtaagaat agcccttctt
    31141 acgaatatcc tctccttgaa aaaggataga accttcaaca ggactatcta gaccagcaag
    31201 tagggacaag agtgtggatt ttcctgctcc tgactcccca ataatactgt aaaattttcc
    31261 aggttcaaaa ttataatcga tctgatatag gactgcttca gcagtattct tataacggta
    31321 ggtaacatct tgtaattgta ataaagtcat gatttctcct tcttaactaa tagatgataa
    31381 aatttctttc ggtgattttc taaataagaa taggaaacaa agggctacag ataagcaact
    31441 aagcagaact agaaaaacat aggattctgc aaaagataag atgctagttg ataaactgct
    31501 tgctttggct agtgtatctt gtaagcttgc ctgatctcca cttgctagta gagtttggag
    31561 tagataactt gtgattccgt ttcctgcaac aaatgctgga agcaaagctc caagagatac
    31621 caaaactacc tctaaacaga attgtaggaa gatcgagctc ttgccttttc caagtgcaag
    31681 taaaatcccc acttcataga cccgttctct caaccagaga gacaaaacca gaattaaggc
    31741 tccagctcct gctatcaaca tcccataaag gaagatggtc aagaaggttt ggaaagttgc
    31801 aactgagtct ttgatttgtt caaaagcctt gttttccttt tcgacttggt agccttgatt
    31861 ttccaaggcc aagttttcta cctgcttcat gagtccgtcc atttccttag gattttctac
    31921 atagaagcgt gctgcactga cttgagcttc actattgccc aaaagggttt ggctactttc
    31981 atagtctgta aagacttgat tttcactgaa gtcagaagac aagcctgtga atttctcttg
    32041 ttttttacca gaaaagatgc cgataatctc aaactctact gtttgtcctt ttccagattc
    32101 agactgacca gcatccaagc caatcttgtc atgaagtgaa agaccgttct tcttagccaa
    32161 ttcttcgtgg ataaggattt tcttggaatc ccctttttga aggtgtcgcc cttcttttag
    32221 attgaaagcc gaactggtaa aggttacatc cttggatgaa tcctcaagag ccgttaagct
    32281 aaccaagtta ttgtctgcag ctgataaatc atcacgctcc acgctctgct caccagtcac
    32341 tgcttccttg tcttttagtt ttgcgaccgt ctcaagttca ggagagacat tttccagccc
    32401 cttaatcttg cttacagatg ctaggtctga caacttgaat gtctgaccat tctctatctt
    32461 cttaatagaa aaagatgtat tgagtgattt ataaagattg ctttctactg ttttgttgga
    32521 cttcatcaga gtcaaacagg ctgaaattcc ggccaataag accaataaaa tcagaaataa
    32581 aataaaactt ctcagtcgct ttctgctgac ataagcccaa gatctttgga ttggattcat
    32641 ttgtcacctc catatttgta agactattat aaaacccaaa tatgaaatgt ttatgaaata
    32701 cgaaaaaaaa tatcgagtag
//
LOCUS       DAVBCA010000020        31002 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.020, whole genome shotgun sequence.
ACCESSION   DAVBCA010000020 DAVBCA010000000
VERSION     DAVBCA010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31002)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31002)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31002
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.020"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(298..516)
                     /locus_tag="VQU19_000865"
     CDS             complement(298..516)
                     /locus_tag="VQU19_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2480135.1"
                     /translation="MVLNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
     gene            complement(762..1040)
                     /locus_tag="VQU19_000866"
     CDS             complement(762..1040)
                     /locus_tag="VQU19_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480136.1"
                     /translation="MKKDKEVYDKVCEYLSPHLNKDMEMLELACWFRVIIVIEANSYV
                     NIRSSRLLPKFKTQKINSWCAAYSIHFNNGYCKQHTNEFKDSLKSLIL"
     gene            complement(1254..2885)
                     /gene="rlmD"
                     /locus_tag="VQU19_000867"
     CDS             complement(1254..2885)
                     /gene="rlmD"
                     /locus_tag="VQU19_000867"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HET2480137.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSLHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWCTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVVIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSQKNASLNKITNAHYVCDTAENAMKKWLKEGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMDLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(2959..3933)
                     /locus_tag="VQU19_000868"
     CDS             complement(2959..3933)
                     /locus_tag="VQU19_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HET2480138.1"
                     /translation="MRKKLFLTSAAVLWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGMEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDVRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(4007..4621)
                     /gene="pmp23"
                     /locus_tag="VQU19_000869"
     CDS             complement(4007..4621)
                     /gene="pmp23"
                     /locus_tag="VQU19_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HET2480139.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(4621..5595)
                     /locus_tag="VQU19_000870"
     CDS             complement(4621..5595)
                     /locus_tag="VQU19_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HET2480140.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSRKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQKENGTYSILIKNIEDIQSK"
     gene            complement(5603..6859)
                     /locus_tag="VQU19_000871"
     CDS             complement(5603..6859)
                     /locus_tag="VQU19_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HET2480141.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYETLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYEE"
     gene            complement(6921..7352)
                     /locus_tag="VQU19_000872"
     CDS             complement(6921..7352)
                     /locus_tag="VQU19_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2480142.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEQEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIF"
     gene            complement(7354..7956)
                     /locus_tag="VQU19_000873"
     CDS             complement(7354..7956)
                     /locus_tag="VQU19_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HET2480143.1"
                     /translation="MMDRIRQELENGGAVVLPTETVYGLFAKALDEKAVDHVYQLKRR
                     PRDKALNLNIASFEDILHFSKNQPTYLQKLVETFLPGPLTIILEANDRVPYWVNSDLA
                     TIGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFL
                     TGQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(7940..8779)
                     /gene="prmC"
                     /locus_tag="VQU19_000874"
     CDS             complement(7940..8779)
                     /gene="prmC"
                     /locus_tag="VQU19_000874"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HET2480144.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALELASENASDQNLN
                     IFFKKSDCFAEISEKYDIIVSNPPYISREDESEVGLNVLHSEPHLALFADEDGLAIYC
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKKVRTLKDQFGQNRMVVVDD
                     GQD"
     gene            complement(8779..9858)
                     /gene="prfA"
                     /locus_tag="VQU19_000875"
     CDS             complement(8779..9858)
                     /gene="prfA"
                     /locus_tag="VQU19_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HET2480145.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(9855..10445)
                     /locus_tag="VQU19_000876"
     CDS             complement(9855..10445)
                     /locus_tag="VQU19_000876"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HET2480146.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRGLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPEINKENEEK"
     gene            10568..10750
                     /locus_tag="VQU19_000877"
     CDS             10568..10750
                     /locus_tag="VQU19_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HET2480147.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            10887..12260
                     /gene="mnmE"
                     /locus_tag="VQU19_000878"
     CDS             10887..12260
                     /gene="mnmE"
                     /locus_tag="VQU19_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HET2480148.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNIRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTKLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEANLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLIEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(12307..13242)
                     /gene="dapA"
                     /locus_tag="VQU19_000879"
     CDS             complement(12307..13242)
                     /gene="dapA"
                     /locus_tag="VQU19_000879"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HET2480149.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKTIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAILNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(13298..14374)
                     /locus_tag="VQU19_000880"
     CDS             complement(13298..14374)
                     /locus_tag="VQU19_000880"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HET2480150.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGSSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPCDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(14716..14788)
                     /locus_tag="VQU19_000881"
     tRNA            complement(14716..14788)
                     /locus_tag="VQU19_000881"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(14753..14755),aa:Thr,seq:ggt)
     gene            complement(14888..15397)
                     /locus_tag="VQU19_000882"
     CDS             complement(14888..15397)
                     /locus_tag="VQU19_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HET2480151.1"
                     /translation="MKKLTIRDIADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(15395..15491)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            15520..15951
                     /locus_tag="VQU19_000883"
     CDS             15520..15951
                     /locus_tag="VQU19_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HET2480152.1"
                     /translation="MKIPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKAYIFRK"
     gene            16033..16410
                     /gene="mscL"
                     /locus_tag="VQU19_000884"
     CDS             16033..16410
                     /gene="mscL"
                     /locus_tag="VQU19_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HET2480153.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(16452..17546)
                     /gene="hemH"
                     /locus_tag="VQU19_000885"
     CDS             complement(16452..17546)
                     /gene="hemH"
                     /locus_tag="VQU19_000885"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HET2480154.1"
                     /translation="MKKAILMMTFGSPEEISFEGVAEFFTNIRRGVRPQDHEIQTLYD
                     NYIRIGGTPLQRITREEVNLVKERLGEEYGIYFANKFSRPFIPDVIKQMETDGVEECI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEVLLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            complement(17624..18456)
                     /gene="srtG2"
                     /locus_tag="VQU19_000886"
                     /pseudo
     CDS             complement(17624..18456)
                     /gene="srtG2"
                     /locus_tag="VQU19_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000218039.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus system class B sortase SrtG2"
     gene            complement(18534..19532)
                     /gene="srtG1"
                     /locus_tag="VQU19_000887"
     CDS             complement(18534..19532)
                     /gene="srtG1"
                     /locus_tag="VQU19_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000851047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus system class B sortase SrtG1"
                     /protein_id="HET2480155.1"
                     /translation="MKTKREKPKKSLSRRLVLAVDGVINHLLLIFAALIFLFGFYALW
                     DSNQVYSLASSSEYEAYRPVTTQQDELASFSGFSKLQELNPEVLGWINVYGTNIDYPL
                     VQAKDNEKYLNKDSKGEFAATGAIFLDARNNPKFEDFNTIIYGHHVENGVMFGDVAKF
                     ADQEFFDQHRYGSIYYNGVEKGLEIFEMLEVDAYDFNIYDPGIQGEDRQQAYLDHLLS
                     VAMHKRDISLSPSDRIILLSTCFLDVTNGRHIVVAKITDTVPKNTFHTKKSKPFPYSV
                     FDDSSLGRFLSSIPLWIWYLILFVLFLLLIFLLLVLYLILRRRRESKKNARSRPFY"
     gene            complement(19550..20746)
                     /gene="pitB"
                     /locus_tag="VQU19_000888"
     CDS             complement(19550..20746)
                     /gene="pitB"
                     /locus_tag="VQU19_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus major pilin PitB"
                     /protein_id="HET2480156.1"
                     /translation="MKKTFFKKLFTASIAAITALSVFRGVPTFADDNSAITKANGENN
                     AVVKINKTLNIAEGITTPTATFTFKFTEKTGQSSNGAPYQTGVAIPDRNVEYNKNDHP
                     TADKIQKATEDIFSGVAYGHAGEYVYDVAEAKTGWQAITKNGKTIDAMRYDKRTYEMH
                     VIVKNKVNGGVYISSVYFKENNKSNAPKVEPSEQGVYNLFDNTYTKDASKEPNPDDPS
                     QVDPNAKALTITKKVDGASGDKTRDFQFHIKIQLPSTNKTAETPVTNIIVKHGSKSEV
                     LAVVTPADTVEYNFTLKDGETFTVEQLPAGSKYTVTETGVAGYTDSSIYTTNGAEQTS
                     QGQKNVDFTLTDILIGEKKNDNKVTNKIDDVTPTGLLIDNLPFILMIGLGLAGFVVLS
                     KKRREA"
     gene            complement(20791..21342)
                     /gene="sipA"
                     /locus_tag="VQU19_000889"
     CDS             complement(20791..21342)
                     /gene="sipA"
                     /locus_tag="VQU19_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus system signal peptidase SipA"
                     /protein_id="HET2480157.1"
                     /translation="MLLKKKHKKPVTQVNRDKSPPSVWGDILYLVSKLLMVGFVLAIL
                     YFFVFGLLRYNDDGMKPALKDGDLVVYYRLDKRYSIGDLLVYSYKGKERVARVIATEG
                     STIDINENGLIINGSPQQEQDIYKETLLYKEGATFPMKVPAGQLFVLGDNRTTAVDSR
                     AFGTIPIQDTQGKVVTVIRRRGF"
     gene            complement(21342..23105)
                     /locus_tag="VQU19_000890"
     CDS             complement(21342..23105)
                     /locus_tag="VQU19_000890"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480158.1"
                     /translation="MIDTPYWFTSGLERGMLNISSLIAPKIDGFYSIKFRYYIGSNDS
                     ITSLKGYISGYNSGIPNEIFSANNENDLQQKFKEITDKILPLGVHHVTISDVLSKYVQ
                     LLPGDASHLRVVKIKDGNEQELNDNQVTIETKKNEQGLVEVTAKFNPSYTLEDDAKYV
                     LKFTVTSSQEAFDAIAGDKTLTSDDAEEADATKLYSNKGAKVAYSYGIGTSRTKIKDY
                     SEKPTFKPSDPLTVPVEIEWKGVDGKSNPSANRPPSVELNLNQKKDGSIKDSYRKVTS
                     PVQTNSFTENTSFAKVAKGYDYELKAPDAPGYTVEVQKTGTKEKPSFKVIYRQLPSLT
                     VKKILEGEQSPNKSFTINVTFSDKDGKPINGKFGNTTVTNGKAQISLKNSQETALSYL
                     PRDTHYKVEEVENSRTGYHVTYEKQEGTLSEDVQTIVTNHRLPTLSVTKKVTGAFANL
                     LQSFKITINVKDAQNKPLNGSYSAIVNNQKTTLQFTNGKATVDLKKDKTIKILDLPLN
                     ARYSIEEEASSSRGYQVSYDKKEGTLDANKSATVTNNKNSVPETGIDFLSSTLVLGVV
                     LPLGGIFFIILLGHLVVNRRK"
     gene            complement(23427..23930)
                     /locus_tag="VQU19_000891"
     CDS             complement(23427..23930)
                     /locus_tag="VQU19_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adhesin"
                     /protein_id="HET2480159.1"
                     /translation="MNVQYDFKKIQYFTSSLVIFLAILFLCAPINSLRADSITEPQTT
                     LHKTITPISGQKDQYELSLDITSKLGTETQSEPLDVVLVADLSGSMEERDVWSYSSRR
                     YISRIEALKHTLKGVNGRQGLIDTILSNSQNRLSIVGFAGKIDNQYNDRYYNEYYLSY
                     QYGTWPN"
     gene            24289..25512
                     /gene="pepT"
                     /locus_tag="VQU19_000892"
     CDS             24289..25512
                     /gene="pepT"
                     /locus_tag="VQU19_000892"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HET2480160.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPRQTLITTDGTTLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEV
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSDRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(25548..26177)
                     /locus_tag="VQU19_000893"
     CDS             complement(25548..26177)
                     /locus_tag="VQU19_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480161.1"
                     /translation="MNKANQLLEQIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDSQTLVLYQKLYDILMSLHSYLESNNGSDADFDKVDA
                     LLDQLSANSKDKTALLESTKAILVLNHQIQSKVSASEETSPARNAEANSDNTSAENQP
                     NATAESNIETASDENKPSNTRDSKPAESTSENETTESSTTTGNQEKPVE"
     gene            26142..26363
                     /locus_tag="VQU19_000894"
     CDS             26142..26363
                     /locus_tag="VQU19_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480162.1"
                     /translation="MDLFQELICLVQKTFYFFLAICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNML"
     gene            complement(26634..26982)
                     /locus_tag="VQU19_000895"
                     /pseudo
     CDS             complement(26634..26982)
                     /locus_tag="VQU19_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(27087..27647)
                     /locus_tag="VQU19_000896"
                     /pseudo
     CDS             complement(27087..27647)
                     /locus_tag="VQU19_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(27873..30992)
                     /gene="phtE"
                     /locus_tag="VQU19_000897"
     CDS             complement(27873..30992)
                     /gene="phtE"
                     /locus_tag="VQU19_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HET2480163.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQISQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPSN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
BASE COUNT         8835 a         6360 c         5686 g        10121 t
ORIGIN      
        1 aaaaggatct agtttttatt tttagttaaa ttatgtctat atttttcatt aactcatcaa
       61 taaaaatttg tttgctaata tctctttctt ctgattttgt ttcaaggatt attgctacat
      121 cattcatatt tttaggtaaa taccaaccat ctggcttatc tgaatatccc ttgaagccta
      181 attgattaaa agtagttatt tgaccagtac cttgattgat gttttcttca acttcattaa
      241 agcctatact tctcttgcat aatccctaac ttgatcttct gtccttaaag tcattttcta
      301 ttcctcgtca ctaaaattat cttcaaaact aataatatca ttaggagtgc aagataaagc
      361 cttacatatt ctttctaaat tcttaaatgt aattggttta tcctttccca tttgtgccat
      421 aacatttgtt gtaagtcctg ccatagctat tacatctgtt ttctttagtc ctttttttgc
      481 taactgtatc cataatggtt tatagttaag taccataata tccctctttt tttcttcatt
      541 aaatttattt aattatagca taaatattga tttcattcaa tcttacattg atttagtgat
      601 ttgttttaga gaatttgttg tgttattccg tccttatttt gccataaatt gttttaagtg
      661 ggacctctta tccttaccat ttttacctcc taattttgag tataaaaaag acgatagagt
      721 ttttaatttc tatcgtctga gatttacata ttaaattttc atcacaaaat aagactcttt
      781 aaagaatctt taaattcatt ggtatgctgc ttacaatatc cattattaaa atggatacta
      841 taagcagcac accaactatt tattttttga gttttaaact ttggtagaag tcttgaactc
      901 cttatattta cataactatt tgcctctata actattatga cacgaaacca acaagcaagt
      961 tcaagcatct ccatatcttt attcaaatga ggactaagat attcacaaac tttatcataa
     1021 acctctttat cttttttcat aaaaggggca tacaacttag caaatttatc ctaaaatttt
     1081 ttgttgcctt tatcaatcat ttcaacgctc ctttaaatat aaaaataatc ctatcaatct
     1141 ttatattgag cctattttct aattgatacc ttgcaagaaa ggaataatag ctgttcctat
     1201 accaagtagg aatgtaataa atgcagaaag tcatatactg tcattctttt ctattaaatc
     1261 attttgaagt gtctcaaagc atccatgatg gcttcttctt tttcaggtgt acactgtgga
     1321 ataatttgtt tatccttttt agacttgttg taatgttctc gtaattctat tccacatttc
     1381 ttttttatct gtgcaatata taatgtcgaa acttttaatt caaatttatt ccaaacatat
     1441 tctttgattt gagcatatgt tgctttgctc tccgcacttg tcaaatccat ctcatccagc
     1501 tcaatttcaa cacttatgtg cttatcgaca tcgagtttgg acaaaagtgc taccgtctcg
     1561 acgtgatgcg tttgaggaaa tagatccacc ggctggactt tcttcaattc atatcccaat
     1621 tcttggtaga gtttgatatc acgcgccatg gttgcgacat tgcaggagat ataggcgatg
     1681 cgatcggctc ctgtttgggc gcttgctttg ataaagcttt ctgtcaagcc cttgcgtgga
     1741 ggatcaacca agataacggt tggttgaata ccttccttga gccatttctt catggcattt
     1801 tcagccgtgt cacagacata gtgggcatta gtaatcttgt tcaaagaagc attcttctgg
     1861 ctattctcaa ccgcttctgg aatcagttca acaccgtaga cttctttgac atgcttggcg
     1921 actgataaac caatggttcc aataccagaa taagcatcaa taaccacgtc atcttttttt
     1981 aactctgcaa agtcaatggc tgtttgatag agtttctccg ccatttcagt attgacttgg
     2041 taaaaggctg ggccagcgat ttggaagtca tttcccaaca tctggtccgt aatatagtct
     2101 tgaccataaa gagtgcacca ctccttacca aaaatcgcat tggtattctg gtcgttgata
     2161 ttttgcatga cagacacaat ctctgggaac tgcttgataa cttgttcaat caattggtca
     2221 acacgaaaaa cttttggacg agttgtcacc aaaacgacca tgatttgtcc tgaatagtga
     2281 ccacgacgca ccacaagatt ccgaatcaat ccagactgtt ccttttcgtc ataaggtttt
     2341 aaatcaaaac gacggagcag gtctcgaaga gctactacga cttggtcaat gacaggatcc
     2401 tggataaaga aatcttcaag gggcatgagg ttgtgcgaat tcttacggaa aaatcctgtt
     2461 tccaagacac cattcactcg acgaacgggc acctgcgcct tattgcgata cttgactgga
     2521 tgttccatac caagcgtttc agcaacttct acatctgcaa ttccagcaat cttgtagaga
     2581 ctgtccttga cttgcttggt tttaaacttg agctgttctg gataagaaag gtgtcctaaa
     2641 tccgcgattc ctgaacgcag gtaagccaaa tctagatctt gattacggtg tagtgactgg
     2701 acaaggtatt tttcaacttt tccaaagcca atctttttat tgaccttgag gacacgcatg
     2761 agaatttttt cactcggtaa agcattctct acaaaaaaga ccaaaccatc taccttggca
     2821 actcctgccc cttcatgggt caaatcaaca atttcaactt ctacaatatc atttttcttt
     2881 aacattcttt tctctttcta ttggccgaca aaaaagacgg caacgttacg attaccatcc
     2941 attataccat gaaatttctt aagaaccaaa actcttgaag aagttgacaa gggcttgcca
     3001 gagggagctt aagaagttac caccgtcctc tagcgcctta tccgcatcaa agttaaggtt
     3061 gatattttta aaactgtcgc cagcttgtga tacgatgctt tgtttaaggt catttagggt
     3121 tttagtgaaa tctgcattgc tgaggatatc actctttgag agattcaagg caaaattgat
     3181 gatgatattg atctggtttc ctgttatgac ctgatcaagt ttgtaatttt ttaaggtatc
     3241 ttcaacaatc ttgcggacat cttcttctgt cagatttccc ttgctttctt tagctttggc
     3301 gagtcctgac ttgatatcag ctagggcaac gtttaattta ttagcatcat agcctgattt
     3361 gtccttgttt tcagcattga tatctgacaa agcctttagc tcttcttgag ccaaatcttt
     3421 attggcttgc ggcaccttgg ctccattagc ttctagcgaa tagtagatcc cagccaaagc
     3481 actctcacct gtaactggaa taggggctgc tacagtgatt ttggcatgtt ccatacccag
     3541 cgttactgct gcgtttcggt acatatcctg agtcacctta gtgatatttt ctggtgtttc
     3601 aatcttgacc tcaagtggcg atttgtcacc tagcttttga atcttggctg atgaatacaa
     3661 ctgtaagcta gagtcattgg ccacattcat gattttagaa taaacatcag gtgtcatggt
     3721 cttgagttct ttggtatctg ttgaggcatt gtagcccagt tttttaagag tttgattttt
     3781 ttggtcttca gatagggagg aacctaggac atattcaggt tggacatagg tttcatcgat
     3841 aaccttttga acatctgttg ctgcatggac gctattcata gctgttactg cccacaagac
     3901 cgcagcactg gtcagaaaga gtttctttct catagggaat ttcctccttt acttttctag
     3961 agtaatatat ctatcttaaa gaaaacttat aacaaaaaca cctggtctag ccagatgttg
     4021 aaaagagagt gaaacatttg atgatgtaaa ggttaagtcg tacctgtcta gaataataat
     4081 agtttcctcc atttacatag agttcagcac cgtgaaaaat ggaaatgggg tgaatataac
     4141 tataagtctt tccagtcgta ttaccaagca agggggcaac agtctcacga gagtactgtt
     4201 tggctagagc caaggtattt tccttgccat tttgggcgat aaaatcgata taggcaggtc
     4261 caaaattata ggcttgaaca gctgtccaga tatctacccc cttcttctgc gccagataga
     4321 gattgcctgt cagagtttga atgccttgcc gaatgctaga ggcattatca ttgatggtgt
     4381 tggttgaacc acttgcagac tcactagact gcataacatc gccttctttt ccttttgttt
     4441 cagtataaat catagcaagc acaagctctt cgtttgctgg ggtgtctttt tcactcaaga
     4501 tttctcgcac catgggttga taggtcatga cttgtttgac atcttgatga acgcggtaag
     4561 ctttatagcc agcaaaaagg aagactgcta gtacaagcac tcttcgaatt cgtttaaaca
     4621 ttatttactt tggatatcct cgatattttt gattaagata gagtaggttc cattttcctt
     4681 ttggataaac tcaacagact cggcgtcttg atagacgtta ttgggaacga tgagctcaat
     4741 tccatttgat aaggagagtt tttggttttc aaatttcttt aattggcgac tggcatcaat
     4801 ttcatcaaat tgaacaggtt ctggtacggc ttctttgact tggtcaataa agctcaaacg
     4861 agccgtcaga ttgttgtcaa aaaggtcatt agccaatttc tcaggtgaca attcattgct
     4921 ttcttctagg ttgttgaaaa tcgctgattt gaccttggat tgaaattgaa aatcatctgt
     4981 gttaaaagat tcagcaattc tctgggctgt tttttccagt tccttgatag attttttagg
     5041 agaaatctta ggagcgacag caagaagatt atctgaaaaa tagttcaaaa aagtcccgtt
     5101 gtacttgatt cgtttttcaa tcaggtgata cttgcgactc tgaagattga ccaccaaggc
     5161 ctcgtcagca cccgttccaa atccaggcag gttattctga gtcagcttga ttggattatc
     5221 aacttctcct ccgaggtggg tcaaggtctc ccgcagggca attcgcaaga aagcgaaatg
     5281 ttctacacct tctttagaaa attgaacaaa aatcaagtca ttggtcttga gattttcaga
     5341 aatgctaaac tcctctttcc agagattagc cagcgttact gatgtctcca acaaatcgtc
     5401 tgtaatatga ttgaagaagg gattttcttc ttcgaaaatc ccagtcttgg cttcatctga
     5461 atacacatgt tcaatttttt tacgtaggta ttcttcgatt tttggagtaa tattgagaaa
     5521 cttatctgct aagaacagct cggtatcatc cggactgaac tggtgaataa tggctttctt
     5581 aatataaatg tccataaaag ttttattcct cgtataatgg gaaggcatct gtcaattctt
     5641 tgactgcact tctcacttct tctaatacag cctcattttc tgaattctta agggttttaa
     5701 tgatgagttc agccactttg cgactttctt cttcaccaaa tccacgtgca gtaatagctg
     5761 ctgctccgat acgaatccca cttgtcttga atggtgacaa ggtttcgtaa gggattgaat
     5821 ttttatttag ggtaatattg acttcatcca gcaagttttg agcaactttt ccgttttcta
     5881 caaccttagt cacatcaaca aggaagagat ggttttcagt tccacctgaa ataatacgga
     5941 aatcagggtc ttgcaagaag acatctgcca tagccttgct gttcttaatt acattggcag
     6001 catattcctt gaaggctgga tccaaaactt ctttgaagga aactgcctta gccgccacaa
     6061 catgctctaa aggaccgccc tgaatacctg ggaaaatagc tgaattgatt tttttagcaa
     6121 gttcttcgtc attggtcaaa atcaaaccac cacgaggtcc acgaagggtt ttgtgggtcg
     6181 ttgttgtagt gatatgagcg tatggcactg ggcttgggtg aagaccagct gcaaccaagc
     6241 cagcgatgtg ggccatatca accataagct tcgcaccgac agcatctgcg atttcacgga
     6301 attttgaaaa gtcaataatt tgagaatagg ctgaagcacc agctacaatc agttttggtt
     6361 ttacttcttg ggcttgtttc aagatagcat caaagtctaa gagttccgtt tcaggatcaa
     6421 cactataaga aacaaagttg taggtttgac cagagaagct aacaggagcc ccatgagtca
     6481 aatgaccacc tgatgccaaa tccattccca taaccgtatc acctggctca atcaaggaca
     6541 tgtaagccgc acagttggcc tgacttcctg agtgaggttg gacattggca aatttagcac
     6601 cgaaaatttc ttttgcgcgt tcaatagcaa gagtctctac aacgtctact acatcagttc
     6661 caccataata acggcgtcct gggtaaccct cggcatattt atttgtcaag atagaccctt
     6721 gagctgccat aacagccttg gaaactacgt tttccgaagc aattaactcg atattatttt
     6781 gttggcgttc ttcttctttg gcaatagcat tccagagatc agcatcatat gctttaaaat
     6841 catctttgtc aaaaatcata ggtcttctcc tttattgtgt gactagtcca ttagtttgat
     6901 tttacaataa gaaaatcaaa ctaaaagatg cgaataaacc gtttctgcat tttatcacaa
     6961 gtatagccaa ctttttcata aaatgcatga gcacccagac gatgattggc agaatttaag
     7021 cggataaacc cataaccaca tcttttggct tcttgttcca acccttgtag taaactttta
     7081 ccgatacctt gaccttgcgc ttgaggtgaa actgctaaag ctaagatatt aaatcctgct
     7141 ttggaataga gtgattcgta aacttcagcg tggacatatc caagtaagac atgattagct
     7201 gcatcctcat agccaagtag gaaatgatgg gaatcctgag acagtctagc tagttggcta
     7261 gccgtttcct ctggactaaa agtataaccc aaagcctctt ggttgatgtc acatatcgct
     7321 ttcacatctg tttcttgcaa atctcttagc atttcaagcc tcctcaaaag aaatctctgg
     7381 caaccgagca agaatatctt ctcgtttaat tgcgccttgg cgtaagattt tcaccttgtc
     7441 tccagacaaa tccacaatag ttgaatcctg tccagttaga aaagcatcgt cttccagacc
     7501 cagaacctct tggtcaaaat ccttcagaat ttgttcaaag gttacaccac ttgcctgacc
     7561 tgagatattg gcagacggcc caatcaaggg acctgtctct cgaattaaat ccagtgtgat
     7621 agggtgactg ggcatccgaa atccaatagt tgcaaggtca gaatttaccc aatagggaac
     7681 tcggtcattg gcttcgagaa taatggtcaa gggacctggc aaaaaggtct ctacaagttt
     7741 ttgtagataa gttggctgat tcttagaaaa gtgcaagata tcctcgaaag aggcgatatt
     7801 gagattgagt gccttatctc taggacgacg tttgagttgg taaacatggt caactgcttt
     7861 ttcatctaag gccttggcaa aaagaccata aacagtctct gtaggtagaa cgacagctcc
     7921 accattttcc aactcttgtc taatcctgtc catcatcaac cacaaccatc ctattttgac
     7981 caaattggtc tttgagtgtt cgaacttttt tttcaggaag atgttttcta aaaagttcgg
     8041 gaacactttg accttgcttg tatccaattt caaggtaaat cttaccacca tccttgagat
     8101 agtcttttgc atcttccgca attctacagt aaatagctag gccatcctcg tctgcaaaga
     8161 gagctagatg aggctccgaa tgcaaaacat tcaagcctac ctctgactca tcttcacgag
     8221 agatataggg tggattggat acaattatat catatttttc agaaatttct gcaaaacaat
     8281 cagatttttt aaaaaatata ttaagatttt gatcgctagc attctctgat gcaagctcta
     8341 aggcctcttg agaaacatct gctgctgtca ctgaccaatc tggtctattt tttgctagag
     8401 cgagagcaat agctccacta cctgttccaa tatccagaac tgagagattc gtctcaagat
     8461 tttcagttag aataagctcc actaactcct ctgtttctgg acgaggaatc aaaacccgtt
     8521 catccacctt taaatgcatt ccataaaaat ctgcctgtcc aatgatgtac tgagctggct
     8581 tgtgagctgc tagttgctgg taaatatctt ctacaaattg tttttcttcc tctgttgtca
     8641 cctcctgctg gagggcaaaa ataaagtctg taaaagatag atttttcaga ctacgataga
     8701 caaaagagag gctttccgct tcctctcctt gtcttatcaa ctcttcttca aaatttgaaa
     8761 ataattgagc taatttcatt atttgtttaa ttcttctagt ttttgtgttt ggtcataaag
     8821 caccaaggca tccacaactt cgtccaattt accagacaaa atcgtatcta gtttttggag
     8881 ggtcaagccg atacggtggt ctgtgacacg gttttgaggg aagttataag ttcggatccg
     8941 ttctgaacgg tcaccagtac cgattgtcga cttacgctca gcgtcttgtt catcctgagc
     9001 aatctgagca aagtggtcag cgacgcgtgc acggataatc ttcatagcct tctcacggtt
     9061 cttctgctgg gtacgttctt cctgcatctc aaccttgata ttggttggca agtgaacgat
     9121 acgaacggca gtcgcaacct tattgacgtt ctgtccacca gcacctgatg cgtggtaaat
     9181 atcaacacga agatcttttg gatcgatatc gtattctact tcttcgactt caggcatgac
     9241 aagaactgtg gcagttgagg tatgaacacg accttggctt tctgtcacgg ggacacgctg
     9301 cacacggtgg gcacctgatt cgtacttaag cttagagtat acagactgac ctgaaaccat
     9361 agcaaccact tctttaaacc caccgacacc attcatagag gcttccatga cttcaaagcg
     9421 ccagccttgg gcttccgcat acttttggta catagttagc aaatctccag cgaaaagtgc
     9481 cgcttcgtct ccaccagctg ctccacggat ttcaaggatg atattcttgt catcgtttgg
     9541 atcctttgga aggagcaaaa ttttcagttt ttcttcatat tcttcttttt cagccttggc
     9601 atctttgagt tcttgcttgg ccatttcttc caagtccgca tctccgcctg attccttaat
     9661 catctcttcg gcatcgacga tattttgaag gacttgttta tactcacggt aggctattac
     9721 ggtatcacga ttggaagctt cttcttttga aagctccata aaacgcttgg tgtctgaaac
     9781 gacatcaggg tcactcagca attctcctag ttcttcataa cggtcttcta cagcttgtag
     9841 ttgatcatag atgttcattt ttcttcattc tccttattga tttcaggggc aaaataatgt
     9901 ttacggcaaa ccgagatata ggtttcatta ccaccaattt ggatctgttc tccatcgtaa
     9961 acgggcagtc catcctgtgt tcgcaacacc atggtcgcct ttttcttgca atactgacag
    10021 atggtcttga tttcgtcaat cttgtctgct aaaagcaaga gatatttgga accttcgaac
    10081 aattcattgc gaaagtcatt tttcaagcca aaagccatga cgggtatgtc taactcgtcc
    10141 acaacacgag ctaggtcata aacatggtgg cgtttgagaa actgggcttc atcgaccaac
    10201 acacagtaag gtttttctgg taggcctcgg atatagccaa agatatccgt tgtttcctca
    10261 atcgcaaggg cagggcgttt catgccaatt cgactcgaca catagccaac accgtcacgc
    10321 gtatccagag ctgaagtcat aatcacaaca ccttttcctt gctcctcata gttataggcc
    10381 accttgagaa tctcgattgt ctttccagag ttcatggtcc cataacgata atacaactgt
    10441 gccatgtttc ttgcttcacg tccatttcta aatttttgct acattctagt atatcataat
    10501 tttcttaagc tttaaacggc aaaatgtggt aaaatggaag aaatcaaaac tagtggagga
    10561 agctattatg ccatttgtac gcatcgattt atttgaagga cgcacgctcg agcaaaagaa
    10621 agctcttgct aaggaagtaa cggaagcagt tgtccgcaac actggagccc ctcaatctgc
    10681 tgtccatgtc atcatcaacg acatgccaga aggaacttac ttcccacaag gggaaatgcg
    10741 tactaaataa gctagcttaa gcagaattgc ttaggctttt tcaatctcca agtagcattc
    10801 attgaagaaa tatcctaaat ttgttacaat ttgaaaagaa acttggagaa tttccaagaa
    10861 aagagctatt aattaaagga aacattatga ttacacgtga atttgatacc atcgctgcta
    10921 tctctactcc actaggtgaa ggggctattg gtattgtccg cctgagcgga acagacagtt
    10981 ttgctattgc gcaaaagatt tttaaaggaa aagacttgaa caaggttgcc agccacactc
    11041 tcaactacgg tcacattatt gatcctctga ctggtaaagt catggacgag gttatggttg
    11101 gggctatgaa gtctccaaag accttcactc gtgaggatat tatcgagatt aacacccacg
    11161 gtggtattgc ggtgaccaat gagattctcc agctagctat ccgtgaagga gctcggttgg
    11221 cagaacctgg tgaatttacc aaacgtgcct ttttaaacgg tcgcgtagat ttgacacagg
    11281 ccgaggcggt gatggatatc atccgcgcca agacagacaa ggccatgaac atcgcggtca
    11341 aacaacttga tggttccctt tctgatctta tcaataatat ccgtcaagaa atccttaaca
    11401 cacttgccca agttgaggtc aatatcgact atcctgagta tgacgatgtt gaggaagcca
    11461 ctactgctgt tgtccgagag aagacaatgg agtttgagca attactaacc aagctcctta
    11521 ggacagcacg tcgtggtaaa atccttcgtg aaggaatttc aacggctatc attggacgtc
    11581 ccaacgttgg gaaatcaagc cttctcaaca acctcttgcg tgaggacaag gctatcgtaa
    11641 ccgatatcgc tgggacaaca cgagatgtca tcgaagagta cgtcaacatc aatggtgtac
    11701 ctctcaaatt gattgataca gctggtattc gtgaaacgga tgatatagtg gaacaaatcg
    11761 gtgttgagcg ttcgaaaaaa gccctcaagg aagccaactt ggttctacta gtgctaaatg
    11821 ccagtgaacc actgactgcg caagacagac aacttcttga aattagccaa gataccaatc
    11881 gcattattct acttaataaa accgacctgc cagaaacgat tgaaacttcg aaactacctg
    11941 aagacgttat ccgtatttca gtccttaaaa accaaaacat cgacaagatt gaagagcgaa
    12001 tcaacaacct cttctttgaa aatgctggct tgattgagca agatgctact tacttgtcaa
    12061 acgcccgtca catttccctg attgaaaaag cagttgaaag cctacaagcc gttaatcaag
    12121 gtcttgagct ggggatgcca gttgatttgc ttcaagttga cttgactcgt acttgggaaa
    12181 tcctcggaga aatcactggg gatgctgctc cagatgaact catcacccaa ctctttagcc
    12241 aattctgttt aggaaaataa gaaaaatcca tgatccttca ttcggtcatg gattttattg
    12301 tctttattag taatctggtc ttaagacccc tgttacagtt gccttagttg cttcgtagtc
    12361 gccatctacg acaaccttga taatgcgttt ggcatcttct tctggtgctg gaacaagagg
    12421 tagacgagtg ggtccagctt caaatcccat atagttaaga attgccttaa ctggagcagg
    12481 acttggataa gagaagagag cattaacctt aggaatgaat ttacgctgaa ttgctgcggc
    12541 tttcttcata tcgctttctg caatggcagt aaacatctcg tgcatttcat ccccatttgt
    12601 atgagaggca acagaaataa ccccatccgc cccaaggttc atggcatgga aagcatctcc
    12661 atcctcacct gtataaatca agaactcttc aggcttgtgc tcaatcaagt aagccatatt
    12721 agccaagcta gtacattctt tgacaccgat aatatttgga tggtcagcca agcgaagcat
    12781 ggtttctgga gtcaattcga caactacacg ccctggaatg ttatagataa taattggtag
    12841 gtcagaagca tctgcaatag tcttaaagtg ctgatacatc ccttcttgag aaggtttgtt
    12901 gtagtaagga acaatagcaa gcccagctgc gaaaccacca aattccgcta cttctttgac
    12961 aaactcaata gagtcacgcg tatcattagt acctacaccc gcaatcaaag gaacgcgtcc
    13021 attgacaacc ttttgtacag ccgcaaacaa ctccaactcc tcatcgtggg tcaaagttgg
    13081 actctcagca gtcgttcctg cgagaagaat tccatccgta tgatgggcca ataaatgctc
    13141 aatcaaggct ggaatagcat caaagttaat agaaccatcc tcatgaaagg gggtaataaa
    13201 ggctgtaatg attttacatt cttttaaatc ttgataagac atgaaaacac ctctctattt
    13261 caaagaagga gttcatctga actcctaaac gatatgacta ttttaattca aatttcaatt
    13321 cggctgttgg acgaaccaat ccacgttcat gaagagtttc agcaatctga actgagttcc
    13381 aagcagcacc tttgagaagg ttatctgaaa caacccacat gtgaattcct ttttctgcat
    13441 ccaagtcttt acggatacga ccaacaaagg tatcacgcga accaactgca ttgatagctt
    13501 gaggatagat ttgatgagct acatcatctt caagaacagc acctgggaag gctgcgatag
    13561 ctgcttttac ttcttcgatt ggagccactt cttttgtttc gatataaaca gactcagagt
    13621 gagctgacaa gactggaata cgcacacatg ttgcagatac tgcaatgcta tcatcttcca
    13681 taattttctt agtttccttg gtcatcttca tctcttcgta cgtgtaatca ttatcagtga
    13741 aaacatcaat ttgtggaaga gcgttaaagg cgataggata atgtttcttg tcaccacctg
    13801 aaggcaaaat ttccgcatgc aaatcacatg gtttcacacc atcattcaag acttcacgaa
    13861 gttcacgttg tgtctcaaga attgctccca taccagcacc tgaaacggct tgataagttg
    13921 aaacaatgat acggtccaag ccccattttt ggcgaaccgg ctcaagagcc accatcattt
    13981 ggattgttga acaattaggg caggcaatga ttccgttgtg ggcatcaagt gcatgagcat
    14041 tgacctctgg aacaaccaaa ggaacatctg gattttgacg gaaataagat gtattatcca
    14101 ctactaccac gccagctttt actgcgtatg gtgcatactt agctgatgta gaactacctg
    14161 ctgaaaagag agcaatatca actccttcaa aagctgtttc agtcgtttct tcaattgtaa
    14221 tatcttgatc tttaaatttc aatgacttac ctgctgaacg tgcagaagca aggtaacgga
    14281 ttttatcgat tggaagtgtt gattcttcca acatttttat catctgagca ccgacagcac
    14341 ctgtcgcgcc gactacagca actgtatatc ccataaataa cctctttcgg aattttctaa
    14401 aaatttctat aatagaagta ttatactact ttttccatga attgcaaagc tttttcatca
    14461 ttttttggaa aataaaaatc ccagtcgcta gactagggac taagaggcat cttcatgtga
    14521 tgagcaggtt cacacaactc atcaaggtcc gctcctgcgt tatgacctcc ttatgctcaa
    14581 tagtagtccg aagactacct atcgactcat cgcatattct atattactag agatacttga
    14641 ttttgtcaat aagaaatttt ttcgatcgag tataacaaaa aactctcgta ttcaagagtt
    14701 tccctataca tatcatgcta attgccggga tcgaaccggc gacctcatcc ttaccatgga
    14761 tgcgctctgc caactgagct aaatcagctt acttaagaag tatactatat tcagaaaaac
    14821 ttgtcaagtt tccttagaaa ttttccatag gaaaaagcca ggtaagaact acctagctta
    14881 tcttcttcta tttacttaaa tcaattcgac gaccaatttt accaataata atcgccccaa
    14941 taatcaatga agcaaattca ccgattcctg ttgtaaacca agtaaggaag aatggtaatt
    15001 ctgctacaat atttaactct gcagcgatag taaacatgga aattgaaaag aggattgaaa
    15061 agaagaaatg atcttttcga atcaatccgt taaagaggta atccttgcta tattttgcaa
    15121 aaagccaaac acctaaactg aggaatacta aggttgaacc accaccaaca aagacatcta
    15181 gcagtccgaa gctaaagaaa ttagcaatca tacaaccgat ggtaactccg atgatgtact
    15241 taggattgta aaaagccata aagttcatca tttctgaaat acgaaactga taagcaccat
    15301 agctgatggc atttaggggc ggtgtgacag tcaaaacgac gtagatagca gcgacgattg
    15361 caatatctgc aatatcacga atagttaatt ttttcatctt ttctcctttg gcggttgccc
    15421 gcgtgtaata tgcttggtga aagaagctaa gcaccaaggg ttgctttatt caaccctact
    15481 agtatagcac aatagcctgc tttatgctat acttaacaca tgaaaattcc tattcaaaaa
    15541 ttttttaaca atgaaatctt agcctatctc ttttttggcc ttgcgacaac tctagtttcg
    15601 attctctcac gactagtcat ttatcaacta agtcatcagg aactcctggc tactgcccta
    15661 gcaaatatta tcggtatcct atttgccttt atcacaaatg atacgattgt atttaagcaa
    15721 aaaaagaaaa atagacttat ccgtttagtg aaattttctc ttgctcgcct ttctactttt
    15781 ctgttagact tgtttttaac ttttctcttt gtaacccaat ttcctcacat tatagggcaa
    15841 ttcgtaactg aaaacattga taagataaat gctattgaaa caataattgc acaaatattc
    15901 attattatca tcaattatat attgagcaag gcctatattt ttagaaaata atgctccatt
    15961 tatgagcctt ttaattgcct tctataatga tttaggatac aatgaaacac gaaacattga
    16021 aaggaaaaca gtatgttaaa aaatctaaaa tcgttcttgc ttcgaggaaa tgttattgac
    16081 cttgctgtcg gtgttgtaat tgcctctgct tttggtgcta tcgttacttc acttgtaaac
    16141 gacattatca ctcctcttat tttaaatccc gctttgaaag ctgctaaagt tgaacgtatc
    16201 gctcaacttt cttggcatgg agtcggctat ggtaacttct taagtgctat tatcaatttt
    16261 atctttgtgg gtaccgccct cttctttatt atcaagggca ttgaaaaagc acagaaactg
    16321 actggcataa agaaagaaaa aactgccgaa aaaaaaccaa ccgaattgga agtccttcaa
    16381 gaaataaaag ctctccttga gaaaaaataa tcgattaaaa ggatctagcg caaagctaaa
    16441 tccttttttc tttactcttt gggtaacttg cctgcttttt caagcatttt tttgatcaga
    16501 taaggcatct taacattctc ccgccctttt ttctcaatca gttttttcac aaattctggc
    16561 atttgtaaat cttcagattc agctaaaatg tttttcgtct cgtctgaagg aactaactca
    16621 tcaaaggtct cttcttctgg gagaaattcc ttaaactctt gattttcatt gactctaact
    16681 gtattgacca aagcatcaat caaacgagaa tctgtatttg gcattggtgg acgatggtag
    16741 tttaccccaa attcctggca taagtcataa cattctacat cattgtcaaa caagacctca
    16801 atatgctcac tgatgaaact aataggtaca aaaatataat ggtctggatg ttctgtctgt
    16861 tctctgagat actccaaaac atctggttta atccatggaa taccaatatc actctcactc
    16921 tgccaagtgt tggtatattg ttctgaactc aagcccagtt tttcagcgac tagcttgcta
    16981 ttttcgaaaa tttggtctat ataaggatca ccaaagtcca aggcaaaaat gggcacacta
    17041 tgggctgaaa agatgacttt aaagctgtct tgctttactt cttcttttaa aatcttagca
    17101 atttcatctg cccaatagtt taagagcact tcttcctgat accagtcctt aatgaccaaa
    17161 aattgaattt gtttgctttc taaaaatttt tcatagccca tgacagagta gaaagaataa
    17221 tggggctcca aaatcaagca gatacattct tcaacaccat cagtttccat ctgcttgatc
    17281 acgtctggaa taaagggacg agaaaatttg ttggcaaagt agataccgta ctcctcccct
    17341 aaacgttctt tgactaaatt gacctcctca cgtgtaatcc gctgcaaagg cgtcccaccg
    17401 atacgaatat agttgtcata gagagtctgg atttcgtggt cttggggtct aactccacga
    17461 cgaatgtttg taaagaattc tgctactcct tcaaaactaa tctcctctgg agatccaaag
    17521 gtcatcatta atatggcttt tttcatgtta tcatccttat gatattattt tctctatcca
    17581 ttctatcatg aaagaaaaaa atagtaaacg tttcctacgt ctactatttc ttttgctctt
    17641 ttgttttttt atctcgtctt ataattagga tgataaggac aagaagtaag aggacgataa
    17701 taaggagtag aaaggctaga atgtaaatcc aatgactggg aattccgtga tcgaaatacc
    17761 gtgttcctac tgcttcccca ctttcatcct gtgctacttt caccggtgca tccgttattt
    17821 tagctaaaag gatatgtcgt ccattagtta tgttaaggaa acatctcgct tgtacttggc
    17881 tttacttagc agatattgat agtaagcctg gtgttcctca tccttggaac tcaaggttcg
    17941 ataaatctcc gtgtcatagg catccacttc taaaatccca aaaatttcaa gaccacgttc
    18001 tcgaccattg tagtagatag aaccgtagcg atgctggtcg aagaattcct tatcagcaaa
    18061 tttcttaatc tcaccgaaca tagcccctga agccatagag tgtccgtaga tgatcgtatt
    18121 aaaatcagta aagttgggat taaagcgata gtcgagaaaa attgatccca ttatcgtata
    18181 atcgccaaag gcattgcggt caaggtattt gacattatcc tgactttgta gaagcggata
    18241 gtctaccttg gtcccatcaa ggctaatcca accgcaaaca tctttgttca agtgctgtag
    18301 ggtttcaaaa cctgtgctcg aagcatcctt ttcaatagga ttatagtgat catagtcact
    18361 tgcttctact actctctgcc aactaaaaag agctacaaaa acacagaaga ataccagaaa
    18421 tacgttttta aatcgcgctc ttttttgaac cgtcatcagc actcctttct atgcgagatt
    18481 tcttaaaagg aaaggaggcg ggacaaaacc gcctcttttc tattcaccct tagtcagtaa
    18541 aagggtctgc ttcttgcatt ttttttactc tctcttctac gacgtaggat caagtagagg
    18601 acaaggagta agaaaatcaa gagcaagaac aatacaaaca agataaggta ccaaatccat
    18661 agtgggattg atgagaggaa acgtccaaga gacgagtcat caaagacact gtatggaaat
    18721 ggttttgatt tttttgtatg gaaagtattt ttagggacgg tgtctgtaat ctttgcgact
    18781 acgatatgac gaccattggt cacatcgaga aaacaggtac tgagtaggat gatacgatca
    18841 ctcggtgaga gtgagatatc ccgcttgtgc atggcgactg agagcaggtg gtctagatag
    18901 gcctgctggc ggtcctcacc ctgtattcct ggatcataga tgttaaagtc ataggcatca
    18961 acctccaaca tctcaaagat ctcgagccct ttttccacac cattgtagta tatactaccg
    19021 taacgatgct ggtcaaaaaa ttcctgatca gcaaacttag ccacatcacc aaacatgacc
    19081 ccattttcta cgtggtgccc gtagataatg gtattaaagt cttcgaactt aggattattt
    19141 cgtgcatcga gaaagatagc gcctgtcgct gcaaactcac ctttggagtc cttgttgaga
    19201 tacttttcat tgtccttggc ttggactaag ggatagtcga tattggtgcc atagacattg
    19261 atccaaccga ggacttcggg attgagttct tggagtttgc tgaagcctga aaaactggcc
    19321 agctcatcct gttgcgtcgt gacaggtcga taagcttcgt actcacttga cgaagctaag
    19381 gagtagactt ggttggaatc ccaaagggcg tagaaaccaa agagaaagat caaagctgca
    19441 aaaatgagca gcaagtgatt gatcacccca tccacagcaa gaacgagacg cctagacaga
    19501 ctcttttttg gtttctcacg cttggttttc atcatctgcc cccagccgtt taggcttctc
    19561 tacgtttttt agacaagaca acaaatccag ccaaaccaag accaatcatc aaaatgaatg
    19621 gaaggttatc aatcaagaga ccagtaggag taacgtcgtc gattttgtta gtaactttgt
    19681 tgtcgttttt cttttcacct atgaggatat ctgttaatgt aaaatctaca tttttttgtc
    19741 cttgagatgt ttgttctgca ccatttgtag tataaattga tgaatctgta taacctgcta
    19801 ctccagtttc agttactgta tatttagaac ctgctggtag ttgttcaact gtaaatgttt
    19861 caccatcttt aagagtaaaa ttgtactcaa ctgtatctgc tggggtcact actgccaaca
    19921 cctctgactt agatccatgt tttactataa tattcgtaac aggggtttct gctgttttat
    19981 ttgtacttgg aagttgaatc ttgatatgga attggaaatc tcttgtttta tcccctgaag
    20041 ctccatcaac ttttttagta attgttaatg ctttcgcatt ggggtctact tgactcggat
    20101 catcaggatt aggctcctta cttgcgtctt tggtatatgt gttatcaaat aaattataaa
    20161 cgccttgttc acttggttct actttagggg cgttagattt attattttcc ttaaagtata
    20221 ctgatgaaat atagacacca ccatttactt tattcttaac aataacgtgc atttcatatg
    20281 tacgtttgtc gtatctcatg gcatcaattg ttttaccatt tttggtaatc gcctgccatc
    20341 cagtttttgc ttccgctaca tcataaacgt attcaccagc atggccataa gcaactcccg
    20401 aaaaaatgtc ttctgttgct ttttgaatct tatcagcagt tgggtgatca tttttattgt
    20461 attctacatt tctatctgga attgcaactc cggtttgata tggcgcaccg ttagaagatt
    20521 gtcctgtttt ttctgtaaac ttaaatgtaa atgtcgctgt tggtgttgtt attccctctg
    20581 caatattcaa cgttttatta atcttcacaa cagcattatt ttcaccattt gctttggtta
    20641 ttgctgaatt atcatccgca aaagtcggga cacctctgaa tacggacaaa gcggttatag
    20701 ctgcaatgct tgcagtgaat agctttttaa agaatgtttt tttcatgatt atttcttttg
    20761 tttttttatt ttcttttttc attatgatca tcaaaagcct cgtcttctaa tgactgttac
    20821 aactttgcct tgagtatcct gtatagggat ggttccaaaa gcacgactgt ctacagccgt
    20881 tgttcgattg tccccgagga caaaaagttg tcctgctggg actttcatcg ggaaggttgc
    20941 cccttcctta tagagcagcg tttctttgta gatatcttgc tcttgttgag gagaaccgtt
    21001 gatgatgaga ccattttcgt ttatatcgat tgtacttcct tcggttgcta tgacacgcgc
    21061 cactctttcc ttacctttat aactatagac tagcaaatca ccaatcgaat agcgtttatc
    21121 caacctataa tagacgacca agtcgccatc ttttaaggcg ggcttcatgc catcgtcatt
    21181 gtatcttaat aatccaaaga cgaaaaagta aaggatggct agtacaaatc caaccatcag
    21241 aagtttactg actaagtaaa ggatatctcc ccagacactc ggcggagact tatcccgatt
    21301 gacttgtgtt actggtttct tatgtttctt tttaagcagc atcacttcct cctattcacc
    21361 acaaggtgac caagtaagat gataaagaag atccctccta gaggaagaac gactccaagc
    21421 acgagagtgc tactcaagaa gtcaattccc gtttcaggta cgctgttttt attattcgtg
    21481 actgtcgcag acttatttgc atcaagagtt ccttcttttt tatcatagga cacctgatac
    21541 ccacgagacg aacttgcttc ttcttcgata ctataacgag catttagagg aaggtcgaga
    21601 atcttgatgg ttttatcttt ctttagatca actgtcgcct taccattggt gaattgtagc
    21661 gttgtttttt gattatttac tattgcacta tacgatccat tcaatggttt attttgcgca
    21721 tcctttacgt taatggtaat cttaaaggat tgcagaagat tagcaaaagc acctgtaact
    21781 ttttttgtga ctgaaagtgt cggaagtctg tggttggtga cgattgtttg aacatcctct
    21841 gacaaagtcc cctcttgttt ttcataggtg acatgatatc ccgttctaga gttctctact
    21901 tcttccacct tatagtgggt atcacgaggc agataactga gggcagtttc ctgactattt
    21961 ttgagagaaa tctgtgcttt cccgttagtc actgttgtat tcccaaactt gccgttaatc
    22021 ggcttgccat ccttatctga aaaggtaaca ttaattgtga aagatttatt aggtgattgt
    22081 tcaccttcta ggattttctt tacggtgaga cttggaagct gtcggtaaat aactttgaag
    22141 gatggtttct ctttcgtacc tgtcttttga acttcgactg tgtatcccgg agcgtctggt
    22201 gctttcagtt cgtagtcata tcccttagct acctttgcaa aactagtatt ttcagtaaaa
    22261 ctattcgttt gaactggact agtgaccttt cgataggaat cctttatact tccatctttc
    22321 ttttggttta agtttaattc gacactaggt ggacgatttg ctgatggatt tgattttcca
    22381 tccacacctt tccactcaat ctctacagga accgtcaatg gatctgacgg cttgaaagtg
    22441 ggcttctcag aatagtcttt tattttggta cgtgaggtcc caataccata ggaataggca
    22501 acttttgccc ccttgttgga gtagagttta gtagcatcgg cttcttcggc atcatcacta
    22561 gtaagtgtct tatcacccgc aatcgcatca aatgcctctt ggctagaggt gacagtaaac
    22621 ttgagaacgt acttggcgtc atcctccaaa gtgtaactcg gattaaactt ggctgttact
    22681 tccactaatc cctgttcgtt cttcttagtt tcaatcgtaa cttgattgtc attcagttct
    22741 tgctcgttac catccttgat tttgacgaca cgaaggtgtg aagcatcacc aggtaacagc
    22801 tgcacgtact tggacaagac atctgatata gttacatggt gtacgcctag aggtagaatt
    22861 ttatctgtga tttctttgaa tttttgttgc aagtcatttt cattattggc agaaaatatt
    22921 tcgttgggga ttccagaatt ataaccactg atatatcctt taagagatgt gatactatcg
    22981 tttgaaccta tataatatct gaatttgatt gaataaaagc catctatttt tggagctatt
    23041 aaactagata tattcagcat tcctctttct aaaccagagg taaaccaata tggagtatca
    23101 atcatacgtc ccacatttgg attagaataa tagttatata ttgttctccc actattagac
    23161 tcgtaataca tattagcttc gccatctgac agcagaataa ctactttttt tgccccagcc
    23221 cttgcacttt gcaacaatct ttgagcttca gttaacccag catttatatt tgtcccagtg
    23281 ccaatgcccg cgtccatacc ataagaacga ctagagtcag caattgttaa cgaactaaca
    23341 atattttttg agctattaga atccgtgctc caagatacta aagttttagc atcatcatat
    23401 gaagagatat ttgaatacca accagctcaa tttggccaag ttccatattg ataactcaga
    23461 taatattcat tataataacg gtcattatac tgattatcaa tctttccggc aaaaccaact
    23521 atagacagac ggttttggga attagaaaga attgtatcaa tgagcccctg acgaccattc
    23581 acacctttca gtgtatgttt tagtgcttca atcctactaa tgtatcgtct actagagtaa
    23641 gaccacacat ctcgctcttc catactccct gaaagatcgg caaccaagac tacatccaag
    23701 ggttctgact gggtctccgt tcccagttta gatgtgatat ccagtgacaa ctcatactgg
    23761 tctttttgcc ctgatatcgg agtaatcgtt ttgtgcagag ttgtctgagg ttcagttatt
    23821 gaatctgcac gtaaagaatt aattggtgca cacaaaaaaa gaatagcgag aaagataact
    23881 aaactactgg taaaatattg aatcttctta aaatcatatt gaacgttcat gctatctccc
    23941 ttgctagaat atgttttaat ctgatactat ataaatctga gacttccata agataattgt
    24001 ataataatat taacttcgtg tcaattaatg tgtttgaaaa catgttatta taaattacaa
    24061 aaaagtatga ttcttctttg tttttcaact ttttctgtgg taaaatggaa aaaatagtaa
    24121 aaaatttcat aaaataaaga tgcatatatt tattctaatc gctcgaaaat ttcttttgaa
    24181 agtcttctga atttgaatta ttatattttt tcaaaattca taaaatttct caaatcatat
    24241 ttttccgaag ttttgtattc tattttatga taaaaaagga gtttttttat gacttatcca
    24301 aatctcttgg accgcttctt aacctacgtt aaggtcaaca cgcgctctga tgaacactct
    24361 actactactc caagtacaca gagtcaggtt gacttcgcaa caaatgtcct aattcctgaa
    24421 atgaaacgtg ttggactgca aaatgtttac tatctaccga atggttttgc tattggaacc
    24481 ttgccagcca acgatccgtc tttaacacgt aagattggtt ttatatcgca catggatact
    24541 gctgatttta atgctgaagg agtcaatcca caggtaattg aaaactacga tggtggtgtg
    24601 attgaactag ggaattctgg tttcaaactc gatccagccg acttcaagag tcttgaaaaa
    24661 tatccaagac aaacactcat cacaacagat ggaacaacct tgctaggtgc tgatgacaag
    24721 tcaggaattg ctgaaattat gacagccatt gaatatctaa ctgctcatcc tgaaattaag
    24781 cactgtgaga ttcgtgttgg ttttggtcca gatgaagaaa tcggtgttgg tgccaataaa
    24841 tttgatgcag aagattttga tgtggatttt gcctacactg ttgatggtgg tccactaggt
    24901 gaacttcagt acgagacttt ctcagccgct ggtgctgaat tgcatttcca aggccgtaat
    24961 gtccaccctg gtactgccaa agggcagatg gtcaatgccc ttcagctagc aattgatttt
    25021 cataatcaac ttccagaaaa tgaccgacct gagttaactg aaggttacca aggtttttac
    25081 catctaatgg atgtgacagg tagtgttgag gaggtgcgtg caagctacat cattcgtgat
    25141 tttgaaaaag atgcctttga agcgcgtaaa gcatccatgc aatctatcgc tgataagatg
    25201 aatgaagaac ttgggagcga ccgtgtcact ctcaacttga cagaccagta ctacaatatg
    25261 aaagaagtca ttgaaaaaga tatgactcca attaccattg ctaaagccgt tatggaagat
    25321 ctaggtatca cgcctattat cgaaccaatc cggggtggaa cagacggctc taagatttcc
    25381 tttatgggaa tcccaactcc gaatatcttt gcaggtggcg aaaatatgca cggacgtttt
    25441 gaatacgtta gccttcagac tatggaacgt gcagttgata ccatcattgg catcgtagct
    25501 tataaaggct aaaaagacga ggtggctcag ctacttcgcc tttcttttta ttctactggt
    25561 ttttcttgat ttccagtagt tgtagaagat tctgttgttt cattttctga agttgattca
    25621 gcaggtttag aatctcttgt attgcttggt ttgttttcgt cgctagcagt ttcaatgtta
    25681 gattctgcag ttgcgtttgg ttggttctca gcactggtgt tatcactatt tgcttcagca
    25741 tttcttgctg gacttgtttc ttcacttgcg ctaacttttg actggatttg atgattcaaa
    25801 actagaatag cttttgtcga ttcaagtaaa gctgttttgt ctttactatt agcagaaagt
    25861 tgatctaata atgcatccac cttatcaaag tccgcatcag atccattatt actttctaaa
    25921 taagagtgaa gcgacatgag aatatcgtag agtttttgat agagtacaag tgtctgagaa
    25981 tcttgctcag cattttcctt ttcttgttga agggcgctag cgatacgagt caaaacatct
    26041 tttacctgac tgtttacttc atccaagtct gcatcagcct tgtttgtggc agcttttaga
    26101 ttttctactt cttctgccaa ggattgtctg attccttctt catggatttg ttccaagagt
    26161 tgatttgcct tgttcaaaag actttctact tcttccttgc tatctgtcgc agattattgg
    26221 ttgctatcta ccatgtactc ctaaaacagg agagttataa tccaagatta caaggcctta
    26281 cagaaataag aaatccagat aagacaatgt tcgtccaaga cgctattcgc ttcgcacagc
    26341 agcacggatt caatatgctt taattttaaa gtttaggtgt caagacctct ttttagtgtg
    26401 cccaaaattt agagaagtaa tcaatcaact aacttttatt tttttcaaac tttcagtaaa
    26461 ctgacctaaa gctaactcaa tctgtctttg tagatgcttc tgctatcagc tagaagttga
    26521 tctacttttg ccaagactgc cttctcatca aaagttccag gttgatagtt ggattgcagg
    26581 gatggaatct tgtttttcaa agccgcttca tatcccttag tttgaacctt gatgtagtga
    26641 ttgtggtcgc catgaggaat cacaaaacct tctgaatctt cacttataat tcgattggca
    26701 tcaaaaacca taaccatctt cttcctcatg gtggacatgt agtgacggat tacttaatac
    26761 agaactagaa gaacttccta cctcttccgt gttagagtgt gatgggggat tgttaagaga
    26821 tgacttagga atatagtgat agtgttcccc atgtcttact atataagcat cacctatatc
    26881 tctgacaata tcattagggt taaagacata tgtggctgct aattcacctg ccgacaagtc
    26941 actctcagga atgaaatgat agtgaccacc atgtggtact attagtagat tgaaatagaa
    27001 tatgagcaaa ttgataaggg gattttaaag taatttctaa caatgattta gaaactatga
    27061 tgtgctattc taaattcaac tcactatata taaccatcat cggtagtata acgtccctgt
    27121 aattttgcta cagatacttc tgcactagct cctttatcgt ctttaccatg ttcttgtttt
    27181 tggcgattga tttcatcttt tgttcgtaca ttttctgcat gagcttgatc tttaaggtaa
    27241 acataatact ttccatctac cttaataata tatcctccct taacctaact gacaatatct
    27301 tgatctttcg gctgatagtt gggggctttc attaatggct cttcactaaa gagcgcatca
    27361 aaaggaactt taccattata gtagtgataa tgatcgccat gagaagttac ataaccttga
    27421 tctgtaatct taataacaat ttgttttgct tgaattcctt ctttttgact aacctagtct
    27481 ggagtcaaat tttcagtctt cttagtgtct ttattactgt ttacatatga aacacgattt
    27541 ttatctgtat tggcctgtta gctatgttgg ttcagagcat aaacacacag acttaaggaa
    27601 aggataacaa cagatccagc tgctatatat ttctttttaa atttcataat tacctcattt
    27661 ctataattat ttatatgatg tcttcattat taaatgatta tagaaattaa ttaaccaatt
    27721 aattaactag taaatattcc acctcttttt aagttgtatg tcaagaaatt ttatatatta
    27781 ataataaaat gaaattctcc caaagtcaga gttttatttc taacttttga gagaacttca
    27841 tttttgattc agactttttc tactgctatt ccttacgcta tgagatcaga taaattcttt
    27901 tttatcactt ctccacttgg caatcttaat tcaatcgttc catccatatt gaatataaca
    27961 ctatctaagc ctaatccgta actagctgta aatttttcta atttttcttg tacaggatct
    28021 actgctggag cttcctctaa tgctggatct aacatagggt cactccccac attcccttct
    28081 ggattcaaca ttccattatc cgttgagttt tctggtttta caggtttttc gtttggtgcc
    28141 tctggtaaag aatctgctgg tttattttct gttggttggt tctcaactgt tccagtagat
    28201 acttttccat tttcagatgg tttattttca ccatttcctt gaggtgcttc tcctgtaaaa
    28261 tctgccatat tctttttaat gacttctccc gatggtaaat ataattcaat tgttccgtcc
    28321 atattaaaca agacattttc tagcttcatc ccataacttt cagcaaattt tgctactttt
    28381 tcttgtacag gatccactgt aggaacttct tctaacgttg aattactagt actattccca
    28441 gtttcagaaa gtttttcttt ttctaccttc tcactagtct ttggttcttc taccttttca
    28501 tcaagttttg agttttcttg tgctttattc cttttaaatt gtggtagaat acttggttta
    28561 tcagtttgat tttctttttc caagataggt acttccacaa tataagtcga ttgattgtcc
    28621 aaataagcat ttgccatgaa ggttacagga attttatttc cggccgttct ggttgttcct
    28681 tggtttaatt tcggaatcgg taatttgatt tcaccaactt tatagttatt ttctaaataa
    28741 gcatttccat gaaattcatc aaacactctg actaaagcat cagttccttt aggcactgca
    28801 aattgagggt tcactcttaa ataagtatcc cctgcatgga aaggatagaa aatcgtttga
    28861 ctggccattt tgtaagctaa agaggttgga actgtaaatg taccatcata acttacttct
    28921 ggataatctt ttgaagcgat agtatactta aatgtttgtc ctggtaaata aggttgatct
    28981 aattcaaagt ttgcaatatt ccctactcct tctccaaata ctttaccaga tactttctcc
    29041 aatacttttc catctggtgt tattaatttt actagcatat tgatacctaa ttttttctcc
    29101 aattcaggcg gaaaactaaa agaaacgcgt ttttgaccat tggctagagt aaagttttga
    29161 ttattaaacg tactattttt taacaaatta acaacattcg ttaattcttc tccagtataa
    29221 actttattcc cttctttttt agcaactcct tcttcgggtt taaacagttc atagttactg
    29281 tgagaatgac caattccaac cggtttatgt tcatcaatcg gatctgcatg atggtgatct
    29341 ccatgcggat aaataatcgc atttttttct ttattcacga caatactttc acgtttgaca
    29401 ccatattgtt tcataatgcc agcaattttt tcttcgattt ttttatctaa atctttcatt
    29461 tctttggcat tacttggata atcctgttca tgagatgaca aagaatctaa tccattatga
    29521 ctagttttaa cttcctctaa atgtttttgc gcagccttaa tttgctcttc tgtcaagtcc
    29581 ttcttgaaga aataatgatt gtggtctccg tgactcatga caaaacctga ttcatcttca
    29641 gcgataatac gattagcatc aaatccgtat ccatcttctt catgtttctc atgtgaagtt
    29701 cctggattga ttggaagaga tggagaaggt gttgctagac tattgtttgg aagagtcggt
    29761 tgcccaattt gatttgattt tggaatgtaa tggaaatgat caccatgtct tacaatataa
    29821 gctgtagccg tttcttcaac gatatctttt ggattaaaaa tataaccatc agatgctgaa
    29881 gagagctcct tacttgtcgt taaagaagaa ggattgcttg aaagactgcc tagactagac
    29941 actacttcat taggttttgc atttgtagaa actgtagaac cagttccact gataggcacc
    30001 attctggcaa tcttttcttc taaggcagaa agcttgctgt aaggaataaa gtggtaatgg
    30061 tcgccatgcg gaatcgcaac tccatttggt gtacgactga taatcttagc agggtcaaag
    30121 accaggccat ctgattcact gtaacgttgg gcgctaggtg aatcatagag ttccttcaaa
    30181 agactctgga gattttcaga tttatttgct ggcttgctag ttgatccttt tgctacagat
    30241 tgcgtgttat tgtcactagc tgttgaagaa tagcttaact gactcggttg catatttttt
    30301 ccagccagat gtgctttagc tgctgctaat tcactagcag ataaatcgct tttgggaatg
    30361 tagtgatagt gacctccatg aggaacgata taagcattac ccgtatcttc gataatatca
    30421 gctggattaa agacataacc atcatttgtc gtatatcgtc cctgagacct tgctacagca
    30481 acattagagt taaccttctc attatctttg acatgttctt gtttttgacg attgatttca
    30541 tctttagttc gaacattatc agcatgagct gcatctttca ggtagacata atattttcca
    30601 tcgaccttga tgatataacc acccttgact tcattgacaa tatcagcgtc tttaagttga
    30661 tagtttggat ccttcatcaa gagttcttca ctaaagaggg catcataagg aactttccca
    30721 ttatagtaat gatagtggtc accgtgtgac gttacatagc cctgatctgt aattttgatt
    30781 acaatttgct cggcctgaat tccttctttc tggctaatct ggtctggtgt caagttttca
    30841 cttttctgac ttgactggct gccatctaca taagagacac gattattgtc cttattttcc
    30901 tgcgaacgat gctggtttag tgcataggca catagactca aggatacgat aacagctgat
    30961 ccagctgcta tatatttttt actgaatttc ataaatccct ca
//
LOCUS       DAVBCA010000021        30864 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.021, whole genome shotgun sequence.
ACCESSION   DAVBCA010000021 DAVBCA010000000
VERSION     DAVBCA010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30864)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30864)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30864
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.021"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..83)
                     /locus_tag="VQU19_000898"
     CDS             complement(<1..83)
                     /locus_tag="VQU19_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HET2480164.1"
                     /translation="MNYEASKQLTDARFKRLVGVQRTTFEE"
     gene            78..332
                     /locus_tag="VQU19_000899"
     CDS             78..332
                     /locus_tag="VQU19_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HET2480165.1"
                     /translation="MHRTTIPYFVSQEVYWKVRNIGAEAIRRNCERGAIFSGKIKHHE
                     DSQFKGDHYVECYAVLDNTVIARDRITVPIDPLCGKDFIE"
     gene            676..2010
                     /gene="trmFO"
                     /locus_tag="VQU19_000900"
     CDS             676..2010
                     /gene="trmFO"
                     /locus_tag="VQU19_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HET2480166.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVANHPLIEVVRDEITELPTDVITVIATGPLTSDALAEKIHALNDGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRIFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEAIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            2094..2831
                     /locus_tag="VQU19_000901"
     CDS             2094..2831
                     /locus_tag="VQU19_000901"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HET2480167.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            2840..3397
                     /gene="frr"
                     /locus_tag="VQU19_000902"
     CDS             2840..3397
                     /gene="frr"
                     /locus_tag="VQU19_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HET2480168.1"
                     /translation="MANAIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRIHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVV
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            3457..4311
                     /gene="cvfB"
                     /locus_tag="VQU19_000903"
     CDS             3457..4311
                     /gene="cvfB"
                     /locus_tag="VQU19_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HET2480169.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTSLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            4320..4535
                     /locus_tag="VQU19_000904"
     CDS             4320..4535
                     /locus_tag="VQU19_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HET2480170.1"
                     /translation="MRKSFYTWLMTERNPKSNNPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            4621..5589
                     /locus_tag="VQU19_000905"
     CDS             4621..5589
                     /locus_tag="VQU19_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HET2480171.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMALVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            5769..6269
                     /locus_tag="VQU19_000906"
     CDS             5769..6269
                     /locus_tag="VQU19_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2480172.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVMDFVYAYPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIA
                     EQSLED"
     gene            6272..6532
                     /locus_tag="VQU19_000907"
                     /pseudo
     CDS             6272..6532
                     /locus_tag="VQU19_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(6899..8010)
                     /gene="ald"
                     /locus_tag="VQU19_000908"
                     /pseudo
     CDS             complement(6899..8010)
                     /gene="ald"
                     /locus_tag="VQU19_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253293.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
     gene            8187..8756
                     /locus_tag="VQU19_000909"
     CDS             8187..8756
                     /locus_tag="VQU19_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2480173.1"
                     /translation="MESIFVKFAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKDNGKFIGTIDLHKIDPVLKKAAIGYI
                     INKKYWNQGLTTEANRAVIELAFEKIGMNKLTALHDKANPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            8824..9474
                     /locus_tag="VQU19_000910"
     CDS             8824..9474
                     /locus_tag="VQU19_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HET2480174.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTSVKETNLQ
                     AEVAAVSKDSSTGKEVNKEEKEEPVEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGAKTIEKLKDYVTVD"
     gene            9458..11698
                     /locus_tag="VQU19_000911"
     CDS             9458..11698
                     /locus_tag="VQU19_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HET2480175.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSVSYFALLGFVFLLVCL
                     FIQFPWKSAGKVLVICGVFGFWFLFQTWQQSQVSQNLVDSVERVRILPDTIKVNGDSL
                     SFRGKSDGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFDYQGY
                     LKTQGIYQTLNIKRIQSLQKVGSWDIGENLSSLRRKAVVWIKMHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMDGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     VFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVASRPLVFGQPNEWLLILLLI
                     SLALVYDLRKNIKKLTVLCLLITGLFLLTKHPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIKKWQEKMTTSNAQRSLIPYLKSRGVAKIDQLILTNTDKEHVGDL
                     SEMTKAFHVGEILVSKDSLKQKEFVAELQATQTKVRSMIVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGLDSW
                     KIESVR"
     gene            11878..12066
                     /locus_tag="VQU19_000912"
     CDS             11878..12066
                     /locus_tag="VQU19_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480176.1"
                     /translation="MTVTKSYKYDWNTVLEYSTNYHDHQYAWIPEWSRYYSYSEYKVG
                     GGWNYARYEVINYYTGGY"
     gene            12098..12685
                     /locus_tag="VQU19_000913"
     CDS             12098..12685
                     /locus_tag="VQU19_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2480177.1"
                     /translation="MLNLTHVTLKTRQVILQDADFTFKKGRIYGLLAINGSGKTTLFR
                     AMSKLLPLSSGHIAVPPSLFYYESVEWLDGNLSGMDYLRLIKNIWKSDLNLRDEIAYW
                     EMADYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDICDRVVTIHQGQIEEV"
     gene            12689..13864
                     /locus_tag="VQU19_000914"
     CDS             12689..13864
                     /locus_tag="VQU19_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480178.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIILALFVSVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWKDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLPKQIDNVDLNWSMGMVLLPCLIIFLLLGILFIERWGSSQKKRIF"
     misc_feature    14038..14169
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            14185..14715
                     /gene="infC"
                     /locus_tag="VQU19_000915"
     CDS             14185..14715
                     /gene="infC"
                     /locus_tag="VQU19_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HET2480179.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     gene            14748..14948
                     /gene="rpmI"
                     /locus_tag="VQU19_000916"
     CDS             14748..14948
                     /gene="rpmI"
                     /locus_tag="VQU19_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HET2480180.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            15000..15359
                     /gene="rplT"
                     /locus_tag="VQU19_000917"
     CDS             15000..15359
                     /gene="rplT"
                     /locus_tag="VQU19_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HET2480181.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            15417..15797
                     /locus_tag="VQU19_000918"
     CDS             15417..15797
                     /locus_tag="VQU19_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET2480182.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            16047..16847
                     /locus_tag="VQU19_000919"
     CDS             16047..16847
                     /locus_tag="VQU19_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HET2480183.1"
                     /translation="MNPTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVNQRVCEDGPVFRTGTVVL"
     gene            16810..17796
                     /locus_tag="VQU19_000920"
     CDS             16810..17796
                     /locus_tag="VQU19_000920"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HET2480184.1"
                     /translation="MVLFSAQEQLYYKEKIMTTNRLQVSLPGLDLKNPIIPASGCFGF
                     GQEYAKYYDLNLLGSIMIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAE
                     KLPWLEREYPNLPIIANVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGL
                     LIGQDPDLAYDVVKAAVEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVG
                     MRFDLKTRKPILANGTGGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEM
                     YLAGASAIGVGTANFTNPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            17838..19739
                     /locus_tag="VQU19_000921"
     CDS             17838..19739
                     /locus_tag="VQU19_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HET2480185.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKIAEKEWVYDS
                     HSQAWYYFKSGGYMTANEWIWDKESWFYLKSDGKMAEKEWVYDSHSQAWYYFKSGGYM
                     AKNETVDGYQLGSDGKWLGGKATNENAAYYQVVPVTANVYDSDGEKLSYISQGSVVWL
                     DKDRKSDDKRLAITISGLSGYMKTEDLQALDASKDFIPYYESDGHRFYHYVAQNASIP
                     VASHLSDMEVGKKYYSADGLHFDGFKLENPFLFKDLTEATNYSAEELDKVFSLLNINN
                     SLLENKGATFKEAEEHYHINALYLLAHSALESNWGRSKIAKDKNNFFGITAYDTTPYL
                     SAKTFDDVDKGILGATKWIKENYIDRGRTFLGNKASGMNVEYASDPYWGEKIASVMMK
                     INEKLGGKD"
     gene            complement(19800..21455)
                     /gene="pavA"
                     /locus_tag="VQU19_000922"
     CDS             complement(19800..21455)
                     /gene="pavA"
                     /locus_tag="VQU19_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HET2480186.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEI
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTKSLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPLANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            21560..22057
                     /gene="ybeY"
                     /locus_tag="VQU19_000923"
     CDS             21560..22057
                     /gene="ybeY"
                     /locus_tag="VQU19_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HET2480187.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLGYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            22038..22433
                     /locus_tag="VQU19_000924"
     CDS             22038..22433
                     /locus_tag="VQU19_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HET2480188.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFAITGIFTAIKEERNMRKHAVTAL
                     VVILAGFGFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            22450..23349
                     /gene="era"
                     /locus_tag="VQU19_000925"
     CDS             22450..23349
                     /gene="era"
                     /locus_tag="VQU19_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HET2480189.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPDRFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            23398..24222
                     /gene="mutM"
                     /locus_tag="VQU19_000926"
     CDS             23398..24222
                     /gene="mutM"
                     /locus_tag="VQU19_000926"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HET2480190.1"
                     /translation="MPELPEVETVCRCLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARSSQTLTAEEATAIHDQTIAVLSQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQGCVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            24222..24827
                     /locus_tag="VQU19_000927"
     CDS             24222..24827
                     /locus_tag="VQU19_000927"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HET2480191.1"
                     /translation="MGKIIGITGGIASGKSTVTNFLRQQGFQVVDADAVVHQLQKPGG
                     RLFEALVQHFWQEIILENGELNRPLLASLIFSNPDEREWSKQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            24814..26013
                     /locus_tag="VQU19_000928"
     CDS             24814..26013
                     /locus_tag="VQU19_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HET2480192.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSEQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            26013..26162
                     /gene="rpmG"
                     /locus_tag="VQU19_000929"
     CDS             26013..26162
                     /gene="rpmG"
                     /locus_tag="VQU19_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET2480193.1"
                     /translation="MRVKINLKCSSCGSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            26202..26435
                     /gene="secG"
                     /locus_tag="VQU19_000930"
     CDS             26202..26435
                     /gene="secG"
                     /locus_tag="VQU19_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HET2480194.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            26537..28891
                     /gene="rnr"
                     /locus_tag="VQU19_000931"
     CDS             26537..28891
                     /gene="rnr"
                     /locus_tag="VQU19_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HET2480195.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKEYHK
                     IVSSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGRSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSHSGRGRGSNRRSDKKEDKRKS
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            28854..29321
                     /gene="smpB"
                     /locus_tag="VQU19_000932"
     CDS             28854..29321
                     /gene="smpB"
                     /locus_tag="VQU19_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HET2480196.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            29337..30197
                     /gene="tehB"
                     /locus_tag="VQU19_000933"
     CDS             29337..30197
                     /gene="tehB"
                     /locus_tag="VQU19_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HET2480197.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEDVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            30270..>30864
                     /gene="coiA"
                     /locus_tag="VQU19_000934"
     CDS             30270..>30864
                     /gene="coiA"
                     /locus_tag="VQU19_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HET2480198.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQG"
BASE COUNT         9168 a         5715 c         7071 g         8910 t
ORIGIN      
        1 atctcttcaa aagtcgtgcg ctgaacacca acaagacgct taaatcgtgc atcagttagt
       61 tgtttacttg cttcataatt catagaacta ctataccata ttttgtttcg caggaagtct
      121 attggaaagt aagaaatatt ggagctgagg cgattagaag aaattgtgag cgtggtgcta
      181 ttttttcagg taaaataaaa catcacgaag attctcagtt taaaggagac cactatgttg
      241 aatgttatgc tgttttagat aatacggtta tagcaagaga tagaataaca gtccctatcg
      301 atccgttatg tggaaaagat tttatagagt agcatataat tgattcttaa ctggaatact
      361 ctctatctct ttacatcaag aaaatgacta aacagggaag tttgccttct tccctttttt
      421 tgttatacta gtagaagaaa aaaatagaaa gatttgtggg agtgaaaaag tccgggggac
      481 tttttcagct tgagccaaga aattcgagag cgaggaaagt ccgggggact ttttcagcct
      541 gagccaagaa attcgagagc gaagtaagtc caatggactt tttcagcctg agccaagaaa
      601 ctcgaaagct cgtaagtctg attggctttt tcaatgtgaa tcttaacttc acactcccaa
      661 agaggtatta gtgtcgtgtc tcaatcttat atcaatgtta tcggtgctgg tttggcaggt
      721 tctgaagcag cttaccaaat cgcagagcgt ggtattccag ttaaactata tgaaatgcgt
      781 ggtgtcaagt cgactcccca gcataaaaca gacaattttg ctgagttggt ttgttccaat
      841 tctttgcgtg gggatgcttt gacaaatgca gttggtcttc tcaaggaaga aatgcgtcgc
      901 ttgggttctg ttatcttgga atctgctgag gctacacgtg ttcctgcagg tggtgccctt
      961 gcagtggacc gtgatggttt ctctcaaatg gtgaccgaaa aagttgccaa ccaccccttg
     1021 attgaagtgg ttcgtgatga aattacagaa ttgccgacag atgttattac ggttatcgct
     1081 actggtcctt tgacaagtga tgccttggct gaaaagattc atgcccttaa tgacggtgat
     1141 ggtttttatt tctacgatgc ggcagcgcct attatcgatg tcaacactat cgatatgagc
     1201 aaggtctacc tcaaatcacg ttatgataag ggagaagcgg cctacctcaa tgcccctatg
     1261 accaagcaag aatttatgga tttccatgaa gctttggtca atgcagaaga agcaccgctt
     1321 aattcttttg aaaaagaaaa gtactttgaa ggctgtatgc ctatcgaagt catggccaaa
     1381 cgtggcatta aaactatgct ttatggccct atgaagccag tcggtcttga gtacccagac
     1441 gactatacag gacctcgtga tggagaattt aaaacacctt atgcggttgt gcaacttcgt
     1501 caggacaatg cagctggtag cctctacaat attgttggtt tccagaccca cctcaaatgg
     1561 ggagaacaaa agcgtatctt ccaaatgatt ccgggtcttg aaaatgcaga gtttgtccgt
     1621 tatggtgtca tgcatcgcaa ttcttacatg gattcaccaa atcttcttga gcagacttac
     1681 cgttctaaga aacaaccaaa tctcttcttt gctggtcaga tgacgggggt ggaaggctat
     1741 gttgagtcgg cggcttcagg cttagttgcg ggaattaacg cagctcgtct cttcaaggaa
     1801 gaaagcgagg ctattttccc cgagacgaca gcgattggaa gcttagctca ttacattacc
     1861 catgccgaca gcaaacattt ccaaccaatg aatgtcaatt ttgggatcat caaggagttg
     1921 gaaggcgagc gtatccgtga taagaaggct cgttatgaaa aaattgcaga gcgtgccctt
     1981 gccgacttag aggaattttt gactgtctaa tttttttgaa agaattgctc atgatactat
     2041 aaaaatctta gaaattgtga taaaataggt aggatgaaag aaggagagtg aaaatggcga
     2101 atcccaagta taaacgtatt ttaatcaagt tatcaggtga agcccttgcc ggtgaacgtg
     2161 gcgtagggat tgatatccaa acagttcaaa caatcgcaaa agagattcaa gaagttcata
     2221 gcttaggtat cgaaattgcc cttgttattg gtggaggaaa tctctggcgt ggagaacctg
     2281 cagcagaagc aggtatggac cgtgttcagg cagattacac tggaatgctt gggactgtta
     2341 tgaatgctct tgtgatggca gattcattgc aacaagttgg ggttgatacg cgtgtacaaa
     2401 cagctattgc tatgcaacaa gtggcagagc cttatgtccg tggacgtgcc cttcgtcacc
     2461 ttgaaaaagg ccgtatcgtt atctttggtg ctggaattgg ttcaccatac ttctcgacag
     2521 atacaacagc ggcccttcgt gcagctgaaa tcgaagcgga tgccatcctc atggctaaaa
     2581 atggtgtcga tggtgtttac aatgccgatc ctaagaaaga taagacagct gttaagtttg
     2641 aagaattgac ccaccgtgac gttatcaata aaggtcttcg tatcatggac tcaacagctt
     2701 caaccctctc aatggacaac gacattgact tggttgtctt caacatgaac caatcaggca
     2761 acatcaaacg tgtcgtattt ggtgaaaata tcggaacaac agtttcaaat aatatcgaag
     2821 aaaaggaata agaaagaata tggctaacgc aattattgaa aaagctaaag agagaatgac
     2881 ccagtctcac caatcacttg ctcgtgaatt tggtggtatc cgtgctggtc gtgccaatgc
     2941 aagcttgctt gaccgtatac atgtagaata ctatggagtt gaaactcctc ttaaccaaat
     3001 cgcttcaatt acgattccag aagcgcgtgt tttgttggta acaccatttg acaagtcttc
     3061 attgaaagac atcgaacgtg ccttgaacgc ttctgatctt ggtatcacac cagctaatga
     3121 cggttctgtg attcgcttgg ttgtcccagc tcttacagaa gagactcgtc gtgaccttgc
     3181 taaagaagtg aagaaggtcg gcgaaaatgc taaagtggct gtccgcaata tccgtcgcga
     3241 tgctatggac gaagctaaga aacaagaaaa agcaaaagaa atcactgaag acgaattgaa
     3301 gactcttgaa aaagacattc aaaaagtaac agacgatgct gttaaacaca tcgacgatat
     3361 gactgccaac aaagagaaag aacttttgga agtctaaaaa taaacagaaa aactcagttg
     3421 gcattgctgg ctgagtttta ttcgaaagaa ggaaatatga atacaaatct tgcaagtttt
     3481 atcgttggac tgatcatcga tgaaaacgac cgtttttact ttgtgcaaaa ggatggtcaa
     3541 acctatgctc ttgctaagga agaaggccaa catacagtag gggatacggt caaaggtttt
     3601 gcatacacgg atatgaagca aaaactccgc ctgacaagct tagaagtgac tgccactcag
     3661 gaccaatttg gttggggacg tgtcacagag gttcgtaagg acttgggtgt ctttgtggat
     3721 acaggccttc ctgacaagga aatcgttgtg tcactcgata ttctccctga gctcaaggaa
     3781 ctctggccta agaagggcga ccaactctac atccgtcttg aagtggataa gaaagaccgt
     3841 atctggggtc tcttggctta tcaagaagac ttccaacgtc ttgctcgtcc tgcctacaac
     3901 aacatgcaga accaaaactg gccagccatt gtttaccgtc tcaagctatc aggaactttt
     3961 gtttacctac cagaaaataa tatgcttggt tttattcatc ctagcgagcg ttacgcagag
     4021 ccacgtttgg ggcaagtatt agatgcgcgc gttattggtt tccgtgaagt ggaccgcact
     4081 ttgaacctct ccctcaaacc acgctccttt gaaatgttgg aaaacgatgc tcagatgatt
     4141 ttgacttatt tggaaagcaa tggcggtttc atgaccttaa atgacaagtc atctccagac
     4201 gacatcaagg caacctttgg catttctaaa ggtcagttca agaaagcttt aggtggtctt
     4261 atgaaggctg gtaaaatcaa gcaggaccag tttggtacag agttgattta gggaggctta
     4321 tgagaaaatc attttacact tggctcatga ccgagcgcaa tcctaaaagt aacaatccca
     4381 aagcaatttt ggcagacctc gcttttgaag aggcagcttt tccaaaacat acagatgatt
     4441 ttgatgaggt cagtcgcttt ttggaggagc atgccagttt ctcttttaac ctaggagatt
     4501 ttgacagcat ttggcaggaa tatctagaac actagcattt attcattggg tttgggctag
     4561 taatttctcc atccctctgc tataataaaa agaaataaaa ggattagaga ggttctttat
     4621 ttgaaggaac attcaataga cattcaactg agtcatccag atgacctgtt tcatcttttt
     4681 ggttccaatg aacgccatct tcgtttgatg gaagaagagc ttgatgttgt gattcatgct
     4741 cgtacggaga ttgtccaggt tttgggagaa gagtctgctt gcgaggaagc ccgtcaggtt
     4801 attcaagctc tcatggcctt ggtaaatcgt gggatgaccg ttggtacgcc agatgtagtg
     4861 acggctatta gtatggtcaa aaatgatgaa attgacaagt ttgtcgccct ttacgaagaa
     4921 gaaatcatca aggataatac tgggaagcct atccgcgtca aaaccttagg tcaaaaactt
     4981 tatgtggaca gtgtcaaaca gcatgatgtg acctttggaa ttgggccagc aggtacaggg
     5041 aagaccttcc ttgcagtgac cttggcagtg actgccctta aacgtgggca agtcaagcga
     5101 attatcctaa ctcgtccagc ggtggaagcg ggagagagtc ttggatttct tccgggtgat
     5161 cttaaggaga aggtggatcc ttaccttcgt cctgtttacg atgccttgta tcaaattctt
     5221 gggaaagacc aaacgactcg tctcatggag cgtgaaatta tcgaaattgc gccccttgcc
     5281 tatatgcgtg gccggacctt ggatgatgcc tttgtcattc tcgatgaggc gcaaaacacg
     5341 accatcatgc agatgaagat gttcttgacg cgtttaggct ttcattctaa gatgattgtc
     5401 aatggagata tcagtcagat tgacctgcca cgtaatgtca agtccggttt gattgatgct
     5461 caagagaaac tcaagaacat ccatcagatt gactttgttc atttttcagc caaggatgtg
     5521 gttcgccatc cagttgtcgc tcagattatc cgagcctatg aatattctac tgaagttgca
     5581 cacgactgat tttgaggaag ttcgcctgca aaagaatata cttttgagag aggaaaatcc
     5641 agttgtatag gctaaaggtt tgagacaacg attaggcacg atggaaagaa cttttatgtg
     5701 gctgatgacg atcagtgcat cttcctgtgt cataatcaca gggcacaaga aagtaggaat
     5761 ttgaaaagat gattgaccaa ctatctaagt attacagttg taggatacta actgaaaagg
     5821 atattccaag tattttatct ttatatgaaa gtaatcctct gtattttcag cattgtccac
     5881 cagagccaaa ttttgcaact gtaaaagagg acatgctttg tctacctgaa ggtaaagcta
     5941 aggctgataa gttttttgtt ggattttgga atggctctga ccttgtggct gttatggatt
     6001 ttgtctatgc atatcctgat gaggagactg tttttattgg tttgtttatg gttgatcaag
     6061 cctatcagag gaaagggatt ggtagtcata ttgtgacaga agcactagct tattttgcta
     6121 agaactttcg aaaggcacgt ttggcttatg ttaagggaaa tccgcaatct cagcattttt
     6181 gggaaaagca gggctttaaa tcaattggat gcgaggttaa gcaagaactc tatacggttg
     6241 ttatcgctga acagagccta gaagattaga aatggcatca agtaagaact atttggaatt
     6301 tgttttggaa caattatcag gattagatga tgtgacttac cgttccatga ttggggagta
     6361 tattctttac ttccgcggca agattattgg cggcatttat gacgatcgct ttttagttaa
     6421 acccgtgcaa gcagtcttag ataagattga ccaatcttct tttgagtttc catacaaagg
     6481 tgccaaagaa atgatttgag tggaagaact tgataataag atgtttctat aagacctgat
     6541 tttagctatg tataaccaac tgccaacgcc caaacctaaa aagaaaaagc aagggtgaac
     6601 gaagtaaaaa agaagtctgc taaggccctg tctttgcacg ggtaaaattt tatatataaa
     6661 aagaagctgg gactaaagag ctcagcttcc tttggtttat ataattgtca ttacaagacg
     6721 aagtggttgg gcgaaactct gttgacttta ttcaatttag agtttcttat gcacaattga
     6781 gtctggaacg aaagtctcca gttgcaaagt atacagtaca ataaaccaac gatgtaatag
     6841 ctgatgacac aaagcacagt gggtaggact tgcgaagtca cccttttctt ttcaaaattt
     6901 atactaaatc attgatatca gtgtagtcac gattaagtcc ttgagcaact ggtaggctag
     6961 tcaagtaacc ttgataagtg gtcacacctt gacgcaagcc ttcatcttca gagattgctt
     7021 gtgcgaatcc tttgccagcc aaagcttcga tataaggaag agtgacattg gttagggcga
     7081 tggttgaagt gcgggcaacc gcaccaggga tattggcaac ggcatagtgg agaacaccgt
     7141 gtttttcata gacgggttca tcgtgcgttg tcacacggtc agctgtttcg ataacgccac
     7201 cttggtcaac agcaacgtca acgatacaga gcctggacgc atttgtttga ccatctcatc
     7261 tgtcaccaat tccggtgctt ttgcaccagg gatgagaatg gctccaatca ccacatcagc
     7321 atctctcaca cttgcttcaa tgttgaatga attagatata atagtttgaa tttgacttcc
     7381 aaagacttct tctagaactg agagacgctt ggcactaata tctaaaatag tcacttgagc
     7441 accaagacca agggcgatgc gggcagcatg tgtaccgacg acaccatcac cgatgatagt
     7501 tacttttcct tttggaacac ctggtacacc accaagtaga acaccagagc caccagcttg
     7561 cttagtaagg aagtgagctc cgatttgaac agccatacga cctgcaacct cactcatagg
     7621 aacgaggagc ggtagttgtc cttgattgtc acgaacagtt tcataggcaa ttcctgttgt
     7681 ttttgctgct aacatagcat ctgctaattc tggagcagcg gccatgtgca agtaggtgaa
     7741 gagaagaaga tcgtcgcgca agtaaccgta ttcagaactt aaaggttctt ttactttcac
     7801 aaccaactct gctgcccaag cttcaccagc agtagcgaca atctcagctc cttgcttttg
     7861 atagtcagca tcagtaaagc cagaaccgag accagcattt gtttcgataa ggacacgatg
     7921 accacgacta actaagctat gaacacctgc aggtgtgagg gcgacacggt tttcgttatt
     7981 tttaatttct tttgggattc cgattaacat tgagataacc tacctttcaa ttgacggtct
     8041 tgttttggtt gtcacattcc agttcataaa tcaaaaatgt gacggtttca ttgtatatga
     8101 aaccgcttca aaaatcaaga aaaacttgtc atccaaattt ttttatgcta gactagtgaa
     8161 aatcaagctc taatggaggg aaaagtatgg aatcaatatt tgtgaaattt gcccagtatc
     8221 cgtctataga aacggagcgt ttattgctta gacctgtaac tttggatgat gcggaagcaa
     8281 tgtttgacta tgcctcggac aagggtaata cacgttacac ttttccaacc aatcaaagct
     8341 tggaagaaac caagaataac attgctcagt tctacttggc taatcccttg ggacgttggg
     8401 ggattgaatt aaaagataac ggcaagttta tcggaactat tgacttacac aagattgatc
     8461 ctgttcttaa gaaggcagct attggctaca ttatcaataa aaagtattgg aatcaaggat
     8521 taacgacaga agccaatcgt gctgtgattg agctagcttt tgagaagata gggatgaata
     8581 agttgactgc ccttcacgat aaggctaatc ccgcgtcagg aaaggtcatg gagaaatcag
     8641 gcatgcgttt ttcccatgca gaaccatatg cttgtatgga ccagcatgaa aaaggccgaa
     8701 tcgtgacaag agttcattat gtcttgacca aggaagacta ttttgcaaat aaataagcag
     8761 ttgaaaagaa atttttcgac tgttttttct tcctcttacg aataatctaa gagaggagaa
     8821 aatatggaag caattatcga gaaaatcaaa gagtataaaa tcatcgtcat ctgtactggt
     8881 ctgggcttgc ttgtaggagg atttttcctg ctaaagccag ctccacaaac atctgtcaaa
     8941 gagacgaatt tgcaggctga agttgcagct gtttccaagg actcatcgac cggaaaggaa
     9001 gtgaacaagg aagagaagga agaaccagtt gaacaagatc taatcacagt agatgtcaaa
     9061 ggtgctgtca aatcgccagg gatttatgac ttgcctgtag gtagtcgagt caatgatgct
     9121 gttcagaagg ctggtggctt gacagagcaa gcagacagca agtcgctcaa tctagctcag
     9181 aaagttagtg atgaggctct ggtttacgtt cctactaagg gagaagaagc agttagtcaa
     9241 cagactggtt cggggacagc ttcttcaaca agcaaggaaa agaaggtcaa tctcaacaag
     9301 gccagtctgg aagaactcaa gcaggtcaag ggactgggag gaaaacgagc tcaggacatt
     9361 attgaccatc gtgaggcaaa tggcaagttc aagtcagtag acgagctcaa gaaggtctct
     9421 ggcattggtg ccaagaccat agaaaaactt aaagactatg ttacagtgga ttaagaattt
     9481 ctctattccc ctaatttacc tgagttttct attactatgg ctttactacg ccattttctc
     9541 agtatcctat tttgctttgt tgggttttgt ttttctgcta gtctgcctct ttatccaatt
     9601 tccttggaaa tcagcaggta aagttctagt gatttgtgga gtctttggct tctggtttct
     9661 gtttcaaact tggcaacaga gtcaagtgag tcaaaatttg gtggattctg ttgaaagggt
     9721 acggatttta ccagacacta ttaaggttaa cggtgacagt ctgtcctttc gtggtaagtc
     9781 tgatggtcgt gctttccaag tctattataa actccagtcc gaggaggaga aagaagcctt
     9841 tcaagcttta actgaccttc atgagatagg actagaaggg aagctttcgg agccagaagg
     9901 gcagagaaat tttggtggct ttgactacca aggctatctg aagactcagg gaatttacca
     9961 gacactcaat attaaaagaa tccagtcact ccaaaaggtt ggcagttggg atataggtga
    10021 aaacctgtcc agtttacgtc gaaaggctgt ggtttggatt aagatgcact tcccagaccc
    10081 tatgcgcaat tacatgacag gactcttgct aggacatctg gacaccgatt ttgaggagat
    10141 gaatgagctt tattccagtt taggaattat tcaccttttt gccttgtcag gtatgcaggt
    10201 agggtttttc atggacggat ttaagaaact acttttacga ttgggcttga cacaagaaaa
    10261 gttgaagtgg ctgacttatc ccttttccct tatctatgcg ggactaactg gattttcagc
    10321 atcggttatt cgcagtctct tgcaaaagct actggctcaa catggggtta agggcttgga
    10381 taattttgcc ttgacggtgc ttgtcctctt tattgtcatg ccaaactttt tcttgacagc
    10441 aggaggagtc ttgtcctgtg cttatgcttt tatcctgacc atgaccagca aagaagggga
    10501 ggggctcaag gctgttacta gtgaaagtct agtcatctcc ttgggcatat tgcccattct
    10561 atccttctat tttgcggaat ttcaaccttg gtctatcctt ttgacctttg tcttttcctt
    10621 tctttttgac ttggtcttct taccgctctt gtctatctta tttgtccttt cctttctcta
    10681 tccagtcatt cagctgaact ttatctttga atggttagag ggcattattc gcttggtctc
    10741 gcaggtggca agtagaccgc ttgtctttgg acaacccaat gaatggcttt taatcctatt
    10801 gttaatttct ttggctttgg tctatgattt gaggaaaaac attaaaaagc taacggtatt
    10861 gtgcttattg attacagggc tctttctcct gaccaagcat ccactggaaa atgaaatcac
    10921 catgctggat gtggggcaag gagaaagtat tttcctacgg gatgtaactg ggaaaaccat
    10981 tctcatagat gtaggtggta aggcagaatc ttataagaaa atcaaaaaat ggcaagaaaa
    11041 gatgacgacc agcaatgccc agcgaagctt gataccctat ctcaaaagtc gaggagtagc
    11101 taagattgac cagctaattt tgactaacac ggacaaggag catgttggag atttgtcaga
    11161 gatgaccaag gctttccatg taggggagat tctagtatca aaagacagtc tgaaacagaa
    11221 ggaatttgtg gcagaactac aggcgactca aacaaaggtg cgtagtatga tagtagggga
    11281 gaacttaccc atttttggaa gtcagttaga agttctatct ccaaggaaaa tgggagatgg
    11341 aggacacgat gataccctag ttctgtatgg gaaattcttg gataagcaat ttctcttcac
    11401 gggaaatttg gaggagaaag gagagaagga cttgctgaag cactatccag acttgaaagt
    11461 aaatgttttg aaagctagcc aacatggcaa taaaaaatca tcaagtccag cctttctaga
    11521 aaaactcaaa ccagagctta ctcttatctc agttggaaag agcaatcgaa tgaaactccc
    11581 ccatcaggaa acattgacac gactggaagg tatcaatagc aaagtttatc gaactgacca
    11641 gcaaggagct atacgtttta aggggttgga tagttggaaa atcgaaagtg ttcgatagga
    11701 aggataaatg ttgtagatta gtgaaataaa ctaaaaattt gttgcataat aatgataaaa
    11761 acggcataat gaaaacgtat tcaatattga ggatataaaa tcattaaaaa tcagcaaaag
    11821 ttgttttagt tagttagttt ataatctatt ggtcttcttc agtccagtgt atctgctgtg
    11881 acagtcacta aaagttacaa gtatgattgg aatacggttt tggaatatag taccaactat
    11941 cacgaccatc agtatgcttg gattccggaa tggtctcgtt attacagcta ttctgagtat
    12001 aaagttggcg gaggctggaa ctacgctcgt tatgaggtca taaactacta tactggaggt
    12061 tattaatcct taaagagtga gaaaaggagg gctggatatg ttaaatctta ctcatgttac
    12121 cttaaaaacg cgacaagtca tcttgcaaga tgcggatttt acctttaaaa agggtaggat
    12181 ttatggcctt cttgctatca atggctcggg aaagacgaca ctattccgag ctatgagcaa
    12241 gttgcttccc cttagtagtg gacacatcgc agttcctcct tctttgtttt attatgagag
    12301 cgttgaatgg ctggatggaa acttaagtgg gatggactac cttcgtctca taaaaaacat
    12361 ctggaagtca gacctaaact tgagagatga aatcgcctac tgggaaatgg ctgactatat
    12421 cagtcttccc atccgcaagt attccttagg gatgaagcaa cgcttggtga ttgctatgta
    12481 ttttctcagt caggccaaat gctggctcat ggatgagatt acaaatggct tagacgagta
    12541 ttatcgacag aagttttttg ataggctagc acaaatcgat agacaagaac agctggttct
    12601 tttaagttcc cactataagg aagagttggt tgatatctgc gatagagtag taaccattca
    12661 tcaggggcag atagaagagg tttagtttat gaaagatgtt agtctatttt tattgaaaaa
    12721 agttttcaaa agtcgtttaa actggattat cttagcttta tttgtatctg tactcggtgt
    12781 taccttttat ttaaatagtc agactgcaaa ctcacacagc ttggagagca ggttggaaag
    12841 tcgcattgca gccaacgaga gggctatcaa tgaaaatgaa gagaaactct cccaaatgtc
    12901 tgataccagc tcggaggaat accagtttgc taaaaataat ttagacgtgc aaaaaaatct
    12961 tttgacgcga aagacagaaa ttctaacttt actaaaagaa gggcgctgga aagaagccta
    13021 ctatctgcag tggaaagatg aagagaagaa ttatgaattt gtatcaaatg acccgactgc
    13081 tagctctggc ttaaaaatgg gggttgaccg cgaacggaag atttaccaag ccctgtatcc
    13141 cttgaacata aaagcacata ctttggagtt tccgacccac gggattgatc agattgtctg
    13201 gattttagag gttatcatcc caagcttgtt tgtggttgcg attattttta tgctaacaca
    13261 actatttgca gaaagatatc aaaatcatct ggacacagct cacttatatc ctgtttcaaa
    13321 agtgacattt gcaatatcct ctcttggagt tggagtggga tatgtaactg tgctgtttat
    13381 cggaatctgt ggcttttctt ttctagtggg aagtctgata agtggttttg gacagttaga
    13441 ttatccctac ccaatttata gcttagtgaa tcaagaagta actattggga aaatacaaga
    13501 tgtattattt cctggcttgc tcttagcttt cttagccttt atcgtcattg tggaagttgt
    13561 gtacttgatt gcttactttt tcaagcaaaa aatgcctgtc ctctttcttt cactcattgg
    13621 gattgttggc ttattgtttg gcatccaaac aattcagcct cttcaaagga ttgcacatct
    13681 gattcccttt acttacttgc gttcagtgga gattttatct ggaagattac ctaagcagat
    13741 tgataatgtc gatctaaatt ggagcatggg aatggtctta cttccttgcc tgattatctt
    13801 tttgctattg ggaattctat ttattgaaag atggggaagt tcacagaaaa aaagaatttt
    13861 ttaatagatt ctagctttcc tataggtagg gaaaataagt aaaaactaac atagagaggg
    13921 aatcaacttg attctctctt tttgattcga aaaccaaacc aaaatacaaa cacaaacttt
    13981 tcaaaaaata actttttatc ttgacaagag ctagaaaact tggtatcata taaaagttga
    14041 gaaaagcaga agtgagagct tctcgccttg tgacattaag ttgcctggcc ctacggatga
    14101 aaagtttcga agaaacgcta tcataacgtg cgggcttgta tatttacgag tccgctattg
    14161 tttttctcta ataaaacaaa agaggtgaaa accatagcaa agcaagactt attcatcaat
    14221 gatgagattc gtgtacgtga agttcgcttg attggtcttg aaggagaaca gctaggcatc
    14281 aagccactca gtgaagcgca agctttggct gataacgcta atgttgacct agtattgatt
    14341 caaccccaag ccaaaccgcc tgttgcaaaa attatggact acggtaagtt caaatttgag
    14401 taccagaaga agcaaaaaga acaacgtaaa aaacaaagcg ttgttactgt gaaagaagtt
    14461 cgtctaagtc caactattga caagggtgac tttgatacaa aacttcgtaa tgcacgtaag
    14521 ttccttgaaa aaggaaataa agttaaggta tctattcgct ttaagggtcg tatgattacc
    14581 cataaagaga ttggtgcaaa agttttagcc gagtttgctg aagcaactca agatattgcc
    14641 atcatcgaac aacgtgctaa aatggatgga cgtcaaatgt tcatgcaatt ggcgccagcg
    14701 actgacaaaa aataattgtc agaaagttaa ataaaggaga aaaaattatg ccaaaacaaa
    14761 aaacacaccg cgcatcagct aaacgtttca aacgtacagg ttctggtgga cttaaacgtt
    14821 tccgtgctta cacttctcac cgtttccacg gaaaaactaa gaaacaacgt cgtcatcttc
    14881 gtaaagcatc tatggtgcat tcaggagatt acaaacgtat caaagcaatg cttactcgct
    14941 tgaaataata gcttgactgt aagtaaacaa ttctaggaaa tatttggagg aaataaaaca
    15001 tggcacgtgt taaaggtggc gttgtatcac gcaaacgtcg taaacgtatt cttaaattag
    15061 caaaaggtta ctatggagct aaacacatct tgttccgtac tgcaaaagaa caagtaatga
    15121 actcttacta ctatgcatac cgtgaccgtc gtcagaaaaa acgtgacttc cgcaaattgt
    15181 ggatcactcg tatcaatgcg gcagctcgta tgaacggact ttcatactca caattgatgc
    15241 atggtttgaa attggctgag atcgaagtta accgtaaaat gcttgctgac ttggctgtta
    15301 acgatgcagt agctttcaca gctcttgcag atgcagctaa agcaaaactt ggtaaataac
    15361 aactgatgag actggaacag gattgtccag tctttttaaa aataaaggag aaaaatatgg
    15421 cttcaaaaat gctacacact tgcttacgag tagaaaatct tgaaaaatca atcgcatttt
    15481 atcaagatgc ttttggtttt aaagaattgc gtcgcagaga ttttccagac catgccttca
    15541 cgattgtcta tctaggtctt gagggtgatg actatgagtt ggagttgact tataactacg
    15601 atcacggtcc gtatgtggtt ggtgatgggt ttgcccatat cgccctcagt acacctgatc
    15661 ttgaggcact tcatcaagaa cacagtgcaa aaggctatga agtgactgag ccaaatggtc
    15721 taccaggaac tacaccaaac tattactttg tcaaagaccc tgatggatat aaggtcgaag
    15781 tcattcgtga aaaataattt cgtgcaagtt aagtagaata ttcgtttttt acttgacttt
    15841 ttttagctga aagagtatac taataaaaat tcaaccttta aggggagtcc agagagactc
    15901 acaaggtgtc agataaaaga atagtgcaat tttctagagg agactttttg agtgtgctct
    15961 cttgtgttgt acgattttaa ctgaggcctt gcactagcaa ggtcttttct ttatctggtc
    16021 cccttaaaat ttaaggagga aaagttatga atcccacatg taagaagcgt ttgggtgtca
    16081 ttcggttgga aaccatgaag gtggttgcac aagaggaaat cgcgccagca atctttgaat
    16141 tagtcctaga aggagaaatg gttgaagcca tgcgagcagg ccaatttctt catctgcgtg
    16201 taccagacga tgcccatctt ttacgtcgtc ctatttcaat ttcgtctatt gacaaggcaa
    16261 acaagcagtg tcacctcatt tatcggattg agggagctgg gactgcaatt ttttcaacct
    16321 taagtcaggg agacactctt gatgtgatgg ggcctcaggg aaatggtttt gacttgtctg
    16381 accttgatga gcagaatcag gttctccttg ttggtggtgg gattggtgtt ccacccttgc
    16441 ttgaggtggc caaggaattg catgaacgtg gagtgaaagt agtgacagtc ctcggttttg
    16501 ctaataagga tgctgttatt ttgaaaacgg aattggctca gtatggtcag gtctttgtaa
    16561 cgacagatga tggttcttat ggcatcaagg gaaatgtttc cgttgttatc aatgatttag
    16621 atagtcagtt tgatgctgtt tactcgtgtg gggctccagg aatgatgaag tatatcaatc
    16681 aaacctttga tgatcaccca agagcctatt tatctctgga atctcgtatg gcttgtggga
    16741 tgggagcttg ctatgcctgt gttctaaaag taccagaaag cgagacggtc aaccaacgcg
    16801 tctgtgaaga tggtcctgtt ttccgcacag gaacagttgt attataagga gaaaattatg
    16861 actacaaatc gattacaagt gtctctacct ggtttggatt tgaaaaatcc gattattcca
    16921 gcatcaggtt gttttggctt tggacaagag tatgccaagt actatgattt aaacctttta
    16981 ggttctatta tgatcaaggc gacaaccctt gaaccacgtt ttgggaaccc aactccaaga
    17041 gtagcagaga cgcctgctgg tatgctcaat gcaattggct tgcaaaatcc tggtttagag
    17101 gttgttttgg ctgaaaagct accttggctg gaaagagaat atccaaatct tcctattatt
    17161 gccaatgtag ctggtttttc aaaacaagag tatgcagctg tttctcatgg gatttccaag
    17221 gcaactaatg taaaagctat cgagctcaat atttcttgtc ccaatgttga ccactgtaat
    17281 catggacttt tgattggtca agatccagat ttggcttatg atgtggtgaa agcagctgtg
    17341 gaagcctcag aagtgccagt ttatgtcaaa ttaaccccga gtgtgaccga tatcgttact
    17401 gtcgcaaaag ctgcagaaga tgcgggagca agtggcttga ccatgatcaa tactctggtt
    17461 ggaatgcgct ttgacctcaa aaccagaaaa ccaatcttgg ccaatggaac aggtggaatg
    17521 tcaggtccag cagtctttcc agtagccctc aaactcatcc gccaagtagc ccaaacaaca
    17581 gacctgccta tcattggaat ggggggagtg gattcggctg aagctgccct agaaatgtat
    17641 ctggctgggg catctgctat cggagttgga acagctaact ttaccaatcc ttatgcctgc
    17701 cctgacatca tcgaaaattt accaaaagtc atggataaat acggtattag cagtctggaa
    17761 gaactccgtc aggaagtaaa agagtctctg aggtaaactg caatcaatct gttcttgatt
    17821 ttttattagt ttgtaatatg aatttaggag aattttggta caataaaata aataagaaca
    17881 gaggaagaag gttaatgaag aaagtaagat ttattttttt agctctgcta tttttcttag
    17941 ctagtccaga gggtgcaatg gctagtgatg gtacttggca aggaaaacag tatctgaaag
    18001 aagatggcag tcaagcagcg aatgagtggg tttttgatac tcattatcaa tcttggttct
    18061 atataaaagc agatgctaac tatgctgaaa atgaatggct aaagcaaggt gacgactatt
    18121 tttacctcaa atctggtggc tatatggcca aatcagaatg ggtagaagac aagggagcct
    18181 tttattatct tgaccaagat ggaaagatga aaagaaatgc ttgggtagga acttcctatg
    18241 ttggtgcaac aggtgccaaa gtaatagaag actgggtcta tgattctcaa tacgatgctt
    18301 ggttttatat caaagcagat ggacagcacg cagagaaaga atggctccaa attaaaggga
    18361 aggactatta tttcaaatcc ggtggttatc tactaacaag tcagtggatt aatcaagctt
    18421 atgtgaatgc tagtggtgcc aaagtacagc aaggttggct ttttgacaaa caataccaat
    18481 cttggtttta cataaaagaa aatggaaact atgctgataa agaatggatt ttcgagaatg
    18541 gtcactatta ttatctaaaa tctggtggct acatggcagc caatgaatgg atttgggata
    18601 aggaatcttg gttttatctc aaatttgatg ggaaaatagc tgaaaaagaa tgggtctacg
    18661 attctcatag tcaagcctgg tactacttca aatccggtgg ttacatgaca gccaatgaat
    18721 ggatttggga taaggaatct tggttttacc tcaagtctga tggcaaaatg gctgaaaaag
    18781 aatgggtcta cgattctcat agtcaagcct ggtactactt caaatctggt ggttacatgg
    18841 cgaaaaatga gacagtagat ggttatcagc ttggaagcga tggtaaatgg cttggaggaa
    18901 aagctacaaa tgaaaatgct gcttactatc aagtagtgcc tgttacagcc aatgtttatg
    18961 attcagatgg tgaaaagctt tcctatatat cgcaaggtag tgtcgtatgg ctagataagg
    19021 atagaaaaag tgatgacaag cgcttggcta ttactatttc tggtttgtca ggctatatga
    19081 aaacagaaga tttacaagcg ctagatgcta gtaaggactt tatcccttat tatgagagtg
    19141 atggccaccg tttttatcac tatgtggctc agaatgctag tatcccagta gcttctcatc
    19201 tttctgatat ggaagtaggc aagaaatatt attcggcaga tggcctgcat tttgatggtt
    19261 ttaagcttga gaatcccttc cttttcaaag atttaacaga ggctacaaac tacagtgctg
    19321 aagaattgga taaggtattt agtttgctaa acattaacaa tagccttttg gagaacaagg
    19381 gcgctacttt taaggaagcc gaagaacatt accatatcaa tgctctttat ctccttgccc
    19441 atagtgccct agaaagtaac tggggaagaa gtaaaattgc caaagataag aataatttct
    19501 ttggcattac agcctatgat acgacccctt acctttctgc taagacattt gatgatgtgg
    19561 ataagggaat tttaggtgca accaagtgga ttaaggaaaa ttatatcgat aggggaagaa
    19621 ctttccttgg aaacaaggct tctggtatga atgtggaata tgcttcagac ccttattggg
    19681 gcgaaaaaat tgctagtgtg atgatgaaaa tcaatgagaa gctaggtggc aaagattagt
    19741 actataagtg aatatgattt gagtgaatag taagttaaaa atcctgattt caagtaaaat
    19801 caggattttt tcatggatgc aatttttttg gagtctggtg tgacgcggag ggtcttttgt
    19861 cctgtgtaag tgacaaagcc gggttttcca ccagttggtt tattgagttt tttgacttca
    19921 atcatatcta cctgcaccag attcgacagg cgcccttgag agaagtaggc agctaactct
    19981 gctgcgtctg tcttgactgc atcagatggg tcaagatttc ctgagatgac aacatggctt
    20041 ccaggaatgt ccttagcatg gaaccaaagt tcctccttgc gggccatttt aaaggtcaat
    20101 tcctcatttt gaagattgtt tcgtccgaca tagatgatgg ttttgccatc gcttgctaga
    20161 tattgttcta gttttttgcg tttctggatt ttctcccgtt gtcttctgcg gataaaacct
    20221 gtttgaatca attcttcacg gatttcagcg atttcttcca gtccagcttg gttgaggacg
    20281 gtttctacac tttccagata gagaatagtg gctttggttt cttcaatcaa atcagtcaag
    20341 tatttgacag cttctttgag tttctgatac cgtttaaaat agcgttgggc attctggttg
    20401 ggagtcagag ccttatcaag cgcaatcatg ataggttggt tggtatagta gttgtctagg
    20461 ataacctggt cttggtcgtt aggcacttgg tggaggaagg ttgtcagcaa ttctcctttt
    20521 tgacgaaatt cttcagcgtt gtctgtcgcc agtaactctt tttcctgttt tttgagtttg
    20581 tgtcggtttt tctgaagttc attttcaaca cgacgaatca gttcactggc ctgctgtttg
    20641 acgcggtcgc gctcagcctt atccttatag taggtgtcca acaaatcaga aagatttgca
    20701 agaggctctc ccacctgatt tgcaaaagga actggactga aggaagtctc agtcaagcat
    20761 ggcttggttt cttgattgaa aaaatttcgg aaagcggaaa gtttttcact aaccagtatc
    20821 ctttccaatt catttgccgt atcgcgtccc agaccttgaa agaggctttg aagatttttt
    20881 gctgttagtt cttgggtttg caggatttca aagagctttt catccttgat agtaaaagga
    20941 ttgagagatt ttgtacttgg cggagcgata taggtcgatc ctggaagtaa ggtgcggtag
    21001 ctattttgtg aaaagccgac gtgtttgata acttcgagga ttttatgact gcttttatcg
    21061 accagtagaa tattactgtg tttccccata atttcgataa tcaaggtagc ctggatatgg
    21121 tctccaatct cgtttttatt ggaaactgta atttccacaa tacggtcatt ttccacttgc
    21181 tcaatcgact caatcagggc cccctgcaaa tactttctca aaaccatgat aaaggtagaa
    21241 ggttgggctg gattttcaaa agtcgtttgg gtcagctgaa tgcgtccaaa aactggatgg
    21301 gcagaaagga gcaggcgatg gctttggcga ttgctgcgga tttgcaagac caactcttgt
    21361 tcaaaaggct gattgatttt ctggatgcga ccattcacta attcgcttcg caattcctca
    21421 actatgtggt gtaaaaaaaa tccgtcaaat gacatcgttc tctccttgtg attgtattcc
    21481 atagtattat atcaaaaagg tagaataaaa tcatggaaat gtggtataat aaagccaagt
    21541 aaagagaaac gagaagcaca tgtatattga aatggtagat gaaactggtc aagtttcaaa
    21601 agaaatgttg caacaaaccc aagaaatttt ggaatttgca gcccaaaaat taggaaaaga
    21661 agacaaggag atggcagtca cttttgtgac caatgagcgt agtcatgaac ttaatctggg
    21721 gtaccgtgac accgaccgtc cgacagatgt catcagcctt gagtataaac cagaattgga
    21781 aattgccttt gacgaagagg atttgcttga aaatccagaa ttggcagaga tgatgtctga
    21841 gtttgatgcc tatattgggg aattgttcat ctctatcgat aaggctcatg agcaggccga
    21901 agaatatggt cacagctttg agcgtgagat gggcttcttg gcagtacacg gctttttaca
    21961 tattaacggc tatgatcact atactccgga agaagaagcg gagatgttcg gtttacaaga
    22021 agaaattttg acagcctatg gactcacaag acaataaacg aaaatggaaa aatcgtgacc
    22081 tgatatccag tttagaattt gccatcacag ggatttttac tgctatcaag gaagaacgca
    22141 atatgcgaaa acatgcagtg acggctctag tggtcatcct tgcaggtttt ggttttcagg
    22201 tgtcacgaat cgaatggctc tttctcctat tgagcatttt cttggtggta gcctttgaaa
    22261 ttatcaattc tgctatcgaa aatgtggtgg atttggccag tcactatcac ttttccatgc
    22321 tggctaaaaa tgccaaggat atggcggctg gcgcggtatt agtggtttct ctttttgcag
    22381 ccttaacagg cgcattgatt tttctcccac gaatctggga tttattattt taaacagtaa
    22441 gaggaaatta tgacttttaa atcaggcttt gtagccattt taggacgtcc caatgttggg
    22501 aagtcaacct ttttaaatca cgttatgggg caaaagattg ccatcatgag tgacaaggcg
    22561 cagacaacgc gcaataaaat catgggaatt tacacgactg ataaggagca aattgtcttt
    22621 atcgacacac cagggattca caaacctaaa acagctctcg gagatttcat ggttgagtct
    22681 gcctacagta cccttcgcga agtggacact gttcttttca tggtgcctgc tgatgaagcg
    22741 cgtggtaagg gggacgatat gattatcgag cgtctcaagg ctgccaaggt tcctgtgatt
    22801 ttggtggtga ataaaatcga taaggtccat ccagaccagc tcttgtctca gattgatgac
    22861 ttccgtaatc aaatggactt taaggaaatt gttccaatct cagcccttca gggaaataac
    22921 gtgtctcgtc tagtggatat tttgagtgaa aatctggatg aaggtttcca atatttcccg
    22981 tctgatcaaa tcacagacca tccagaccgt ttcttagttt cagaaatggt tcgcgagaaa
    23041 gtcttgcacc taactcgtga agagattccg cattctgtag cagtagttgt tgactctatg
    23101 aaacgagacg aagagacaga caaggttcac atccgtgcaa ccatcatggt cgagcgcgat
    23161 agccaaaaag ggattatcat cggtaaaggt ggcgctatgc ttaagaaaat cggtagcatg
    23221 gcccgtcgtg atatcgaact catgctagga gacaaggtct tcctagaaac ctgggtcaag
    23281 gtcaagaaaa actggcgcga taaaaagcta gatttggctg actttggcta taatgaaaga
    23341 gaatactaag tagaggtggg ctcatgcctg cttcttgttt ttacagaagg aggacttatg
    23401 cctgaattac ctgaggttga aaccgtttgt cgttgcttag aaaaattgat tataggaaag
    23461 aagatttcga gtatagaaat tcgctacccc aagatgatta agacggattt ggaagagttt
    23521 caaagggaat tgcctagtca gattatcgag tcaatgggac gtcgtggaaa atatttgctt
    23581 ttttatctga cagacaaggt tttgatttcc catttgcgga tggagggcaa gtatttttac
    23641 tatccagacc aaggacctga acgcaagcat gcccatgttt tctttcattt tgaagatggt
    23701 ggcacgcttg tttatgagga tgttcgcaag tttggaacca tggaactctt ggtgcctgac
    23761 cttttagacg cctactttat ttctaaaaaa ttaggtcctg aaccaagcga acaagacttt
    23821 gatttacagg tctttcaatc tgcccttgcc aagtccaaaa agcctatcaa atcccatctc
    23881 ctagaccaga ccttggtagc tggacttggc aatatctatg tggatgaggt tctctggcga
    23941 gctcaggttc atccagctag atcttcccag actttgacag cagaagaagc gacagctatt
    24001 catgaccaaa ccattgctgt tttgagccag gctgttgaaa aaggcggttc caccattcgg
    24061 acctatacca atgcctttgg ggaagatgga agcatgcagg attttcatca ggtctatgat
    24121 aagactggtc aaggatgtgt acgctgtggt accatcattg agaaaattca actaggtgga
    24181 cgtggaaccc acttttgtcc aaactgtcaa aggagggact gatgggaaaa atcatcggaa
    24241 tcactggggg aattgcctct ggtaagtcaa ctgtgacaaa ttttctaaga cagcaaggct
    24301 ttcaagtagt ggatgccgac gcagtcgtcc accaactaca gaaacctggt ggtcgtctgt
    24361 ttgaggctct agtacagcac ttttggcaag aaatcattct tgaaaacgga gaactcaatc
    24421 gccctctcct agctagtctc atcttttcaa atcctgatga acgagaatgg tctaagcaaa
    24481 ttcaagggga gattatccgt gaggaactgg ctactttgag agaacagttg gctcagacag
    24541 aagagatttt cttcatggat attcccctac tttttgagca ggactacagc gattggtttg
    24601 ctgagacttg gttggtctat gtggaccgag atgcccaagt agaacgctta atgaaaaggg
    24661 accagttgtc caaagatgaa gctgagtctc gtctggcagc ccagtggcct ttagaaaaaa
    24721 agaaagattt ggccagccag gttcttgata ataatggcaa tcagaaccag cttcttaatc
    24781 aagtgcatat ccttcttgag ggaggtaggc aagatgacag agattaactg gaaggataat
    24841 ctgcgcattg cctggtttgg taattttctg acaggagcca gtatttcttt ggttgtacct
    24901 tttatgccta tcttcgtgga aaatctaggt gtagggagtg agcaagtcgc tttttatgca
    24961 ggcttagcaa tttctgtctc tgctatttcc gcggcgctct tttctcctat ttggggtatt
    25021 cttgctgaca aatacggccg aaaacccatg atgattcggg caggtcttgc tatgactatc
    25081 actatgggag gcttggcctt tgtcccaaat atctattggt taatctttct tcgtttacta
    25141 aacggtgtat ttgcaggttt tgttcctaat gcaacggcac tgatagccag tcaggttcca
    25201 aaggagaaat caggctctgc cttaggtact ttgtctacag gcgtagttgc aggtactcta
    25261 actggtccct ttattggtgg ctttatcgca gaattatttg gcattcgtac agttttctta
    25321 ctggttggta gttttctatt tttagctgct attttgacta tttgctttat caaggaagat
    25381 tttcaaccag tagccaagga aaaggctatt ccaacaaagg aattatttac ctcggttaaa
    25441 tatccctatc ttttgctcaa tctcttttta accagttttg tcatccaatt ttcagctcaa
    25501 tcgattggcc ctattttggc tctttatgta cgcgatttag ggcagacaga gaatcttctt
    25561 tttgtctctg gtttgattgt gtccagtatg ggcttttcca gcatgatgag tgcaggagtc
    25621 atgggcaagc taggtgacaa ggtgggcaat catcgtctct tggttgtcgc ccagttttat
    25681 tcagtcatca tctatctcct ctgtgccaat gcctctagcc cccttcaact aggactctat
    25741 cgtttcctct ttggattggg aaccggtgcc ttgattcccg gggttaatgc cctactcagc
    25801 aaaatgactc ccaaagccgg catttcgagg gtctttgcct tcaatcaggt attcttttat
    25861 ctgggaggtg ttgttggtcc catggcaggt tctgcagtag caggtcaatt tggctaccat
    25921 gctgtctttt atgcgacgag cctttgtgtt gcctttagtt gtctctttaa cctgattcaa
    25981 tttcgaacat tattaaaagt aaaggaaatc tagtgcgagt aaaaattaat ctcaaatgct
    26041 cctcttgtgg cagtatcaat tacctaacca gtaaaaattc aaaaacccat ccagacaaga
    26101 ttgaggtttt aaagtattgt cccaaggaaa gaaaagtaac cctacatctt gaatctaagt
    26161 agattttatg gtaaaataat agggatttta aggagtttga tatgtataac ctattattaa
    26221 ccattttatt agtattatct gttgtgattg tgattgcaat tttcatgcaa ccaaccaaaa
    26281 accaatccag caatgtattt gatgccagtt caggtgattt gtttgaacgt agtaaagctc
    26341 gcggttttga agctgtaatg cagcgtttga cagggatttt agtctttttc tggctagcca
    26401 ttgccttagc attgacggta ttatcaagta gataagaaaa taatgggcag gactaggtct
    26461 ttgcctcttt ttatttttaa aggatgtttg agaaggtttt acagtaaaag aaaattaaaa
    26521 aatctagaaa gaaaatatga aagatagaat aaaagaatat ttacaagaca agggaaaggt
    26581 gactgttaat gatttggctc aggctttggg aaaagacagt tccaaggatt ttcgtgagtt
    26641 gattaaaacc ttgtccttaa tggaaagaaa gcaccaaatt cgttttgaag aagatggtag
    26701 tctgacatta gaaattaaga aaaaacatga gattaccctc aaggggattt ttcatgccca
    26761 taaaaatggc tttggctttg ttagtctgga aggcgaggag gacgaccttt ttgtagggaa
    26821 aaatgatgtc aactatgcta ttgatggtga taccgtcgag gtagtgatta agaaagtcgc
    26881 tgaccgcaat aagggaacag cagcagaagc caaaattatt gatatcctag aacacagttt
    26941 gacaacagtt gtcgggcaaa tcgttctgga tcaggaaaaa cctaagtatg ctggctatat
    27001 tcgttcaaaa aatcagaaaa tcagtcaacc gatttatgtt aagaaaccag ccctaaaatt
    27061 agaaggaaca gaagttctca aagtctttat cgataaatac ccaagcaaga aacatgattt
    27121 ctttgtcgcg agtgttctcg atgtagtggg acactcaacg gatgtcggaa ttgatgttct
    27181 tgaggtcttg gaatcaatgg acattgtatc cgagtttcca gaagctgttg ttaaggaagc
    27241 agaaagtgtg cctgatgctc cgtctcaaaa ggatatggaa ggtcgtctgg atctaagaga
    27301 tgaaattacc tttaccattg acggtgcgga tgccaaggac ttggacgatg cagtgcatat
    27361 caaggctctg aaaaatggca atctggagct tggggttcac atcgcagatg tttcttatta
    27421 tgtgaccgag gggtctgccc ttgacaagga agcccttaac cgtgcgactt ctgtttacgt
    27481 gacagaccga gtggtgccaa tgcttccaga acgactatca aatggcatct gctctctcaa
    27541 tccccaagtt gaccgcctga cccagtctgc tattatggag attgataaac atggtcgtgt
    27601 ggtcaactat accattacac aaacagttat caagaccagt tttcgtatga cctatagcga
    27661 tgtcaatgat atcctagctg gcgatgaaga aaagagaaaa gaatatcata aaattgtatc
    27721 aagtatcgaa ctcatggcca agcttcatga aactttagaa aacatgcgtg tgaaacgtgg
    27781 agctctcaat tttgatacca atgaagcgaa gattttagtg gataaacaag gtaagcctgt
    27841 tgatatcgtt cttcggcagc gtggtattgc cgagcggatg attgagtctt ttatgttgat
    27901 ggctaatgaa acagttgccg aacatttcag caagttggat ttgcctttta tctatcgaat
    27961 tcacgaggag cctaaggctg aaaaggttca gaagtttatt gattatgctt cgagttttgg
    28021 cttgcgcatt tatggaactg ccagtgagat tagtcaggag gcacttcaag acatcatgcg
    28081 tgctgttgag ggagaacctt atgcagatgt attgtccatg atgcttcttc gctctatgca
    28141 gcaggctcgt tattcggagc acaatcacgg ccactatgga ctagctgctg actattatac
    28201 tcactttacc agtccaattc gtcgttatcc agaccttctt gttcaccgta tgattcggga
    28261 ttacggccgt tctaaggaaa tagcagagca ttttgaacaa gtgattccag agattgcgac
    28321 ccagtcttcc aaccgtgaac gtcgtgccat agaagctgag cgtgaagtcg aagccatgaa
    28381 aaaggctgag tatatggaag aatacgtggg tgaagagtat gatgcagttg tatcaagtat
    28441 tgtcaaattc ggtctctttg tcgaattgcc aaacacagtt gaaggcttga ttcacatcac
    28501 taatctacct gaattttatc atttcaatga gcgtgatttg actcttcgtg gagaaaaatc
    28561 aggtatcact ttccgagtgg gtcagcagat ccgtatccgt gttgaaagag cggataaaat
    28621 gactggagag attgattttt cattcgtacc tagtgagttt gatgtgattg aaaaaggctt
    28681 gaaacagtct agtcatagtg gcagagggcg tggttcaaat cgtcgttcgg ataagaagga
    28741 agacaagaga aaatcaggac gctcaaatga taagcgtaag cattcacaaa aagacaagaa
    28801 gaaaaaagga aagaaacctt tttacaagga agtagctaag aaaggagcca agcatggcaa
    28861 agggcgaggg aaaggtcgtc gcacaaaata aaaaggcacg ccacgactat acaatcgtag
    28921 atacgctaga ggcagggatg gtcctgactg gaactgaaat caagagtgta cgagctgctc
    28981 gaattaatct caaggatggc tttgctcaag tgaaaaatgg agaagtttgg ctgagcaatg
    29041 ttcatatcgc gccttacgaa gagggcaata tctggaacca ggaaccagaa cgtcgtcgta
    29101 aactcctgct ccataaaaag caaattcaaa aattggaaca agagaccaaa gggacaggaa
    29161 tgaccttagt tccccttaag gtctatataa aagatggcta cgctaagctt cttttaggac
    29221 ttgccaaagg gaagcatgac tatgacaaac gggagtctat caaacgtcgt gagcaaaatc
    29281 gagatatcgc gcgtgtgatg aaagctgtta atcagcgata aaaagaggaa ttgaaaatgg
    29341 aaaaattagt tgcctataaa cgcatgcctt tgtggaataa acaaacaatg cctgaagatg
    29401 ttcagcaaaa gcacaataca aaagttggga cttgggggaa aattactgtc ttgaagggag
    29461 ctctcaagtt tattgaattg acagaagaag gggaagttct agctgaacac ctctttgaag
    29521 caggggcaga caatccaatg gcccaacctc aagcctggca ccgagtggaa gctgccacag
    29581 atgatgtgga atggtacttg gaattttatt gtaaacctga ggattatttt gctaaaaaat
    29641 acaataccaa tcctgttcat tcagaggtcc tagaggccat gcagacagtg aaacaaggga
    29701 aagctttgga tttgggttgt ggtcaggggc gtaattctct ttttctagcc cagcaagatt
    29761 ttgatgtgac ggctgtagat caaaatggac tagctcttga aatcttgcaa agcattgtgg
    29821 agcaggaaga tttggacatg cctgttggcc tttacgatat caattcagct agcattgaac
    29881 aagaatatga ttttatcgtt tcaacagttg ttctcatgtt tctacaagcg gaccgcattc
    29941 cagctattat tcaaaatatg caggagaaaa ccagtgttgg tggttacaac cttatcgttt
    30001 gtgccatgga cacggaggat tatccttgct cggttaattt cccattcacc tttaaagaag
    30061 gagaactggc agactattac aaggattggg aattggttaa gtacaatgaa aatccaggcc
    30121 atttgcaccg tcgcgatgag aatggcaatc gtattcaact acgctttgcg accttactag
    30181 ctaagaaaat caagtaaaca cacatgaaga ttaggaattt tcctgatctt ttttcttttt
    30241 tacgaatgat atagaaaagg agggaattca tgtttgttgc gagagatgct aggggagaat
    30301 tggtaaatgt gttagaggat aaacttgaga agcaagcata cacctgccca gcttgtggag
    30361 gccagctcca tttgcgtcaa ggaccaagtg tacggacgca ttttgcccat aaatccttaa
    30421 aagactgtga ttttttcttt gaaaatgaaa gtccagaaca cctggccaat aaggaatccc
    30481 tctatcactg gttgaaaaaa gagacaaagg ttcaattaga gtacccgctt tcagaactta
    30541 aacagattgc ggatgtattt gtaaatggca atctagctct agaagttcag tgtagtccct
    30601 tgcctcagaa agtccttaaa gagcgaagtg agggatatcg tagtcagggt taccaagtac
    30661 tgtggttgct gggtcaaaaa ctgtggctca aggagcgttt gactcgtcta cagcaaggtt
    30721 ttctttattt cagtcaaaac atgggctttt atgtttggga attagacaag gaaaaacaag
    30781 ttttaagact caaatacctg atttaccagg atctccgcgg taaactccat tatcaaatca
    30841 aggaattttc ctatggtcaa ggta
//
LOCUS       DAVBCA010000022        30074 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.022, whole genome shotgun sequence.
ACCESSION   DAVBCA010000022 DAVBCA010000000
VERSION     DAVBCA010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30074)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30074)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30074
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.022"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            51..1100
                     /locus_tag="VQU19_000935"
     CDS             51..1100
                     /locus_tag="VQU19_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HET2480199.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRAEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAVHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGSNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(1200..5042)
                     /gene="spuA"
                     /locus_tag="VQU19_000936"
     CDS             complement(1200..5042)
                     /gene="spuA"
                     /locus_tag="VQU19_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HET2480200.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPGNANASLEKTEEKPAASPA
                     DPAPQTGQDRSSEPTTSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDD
                     VEKPSENWPNGALSFKDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVE
                     KLVPKMNEAWLDQDYKVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQW
                     PDGTDFTATGKYGRYIDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQ
                     IFLKDDDESIYTNPYYVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHL
                     GNKVTITDVAIDEAGKKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGK
                     LGADLKEEGKQVDLTLWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDST
                     NKLGITDFTGYYYQYQIERQGKTVLALDPYAKSLAAWNSDDSKIDDAHKVAKAAFVDP
                     AKLGPQDLTYGKIHNFKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDY
                     LKDLGVTHIQLLPVLSYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSD
                     PKNPEKRIAEFKNLINEIHKRGMGAILDVVYNHTAKVDLFEDLEPNYYHFMDADGTPR
                     TSFGGGRLGTTHHMTKRLLIDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARAL
                     NPNLIMLGEGWRTYAGDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPA
                     FITGGKRDVNTIFKNLIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKA
                     ENYAEIHRRLRLGNLMVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHL
                     LRDKDGNPFDYPYFIHDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQS
                     TDAFRLKSLQDIKDRVHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKARE
                     FNLGTAFAHLRNAEVLADENQAGSVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTS
                     HESTAEEKPDSTPSKPEHQNEASHPEHQDPAPEARPDSTKPDTKVADAENKPSQATAD
                     SQAEQPAQEAQASSVKEAVRNESVENSSKKNIPATPDRQAELPNTGIKNENKLLFAGI
                     SLLALLGLGFLLKNKKEN"
     gene            5459..5872
                     /gene="rpsL"
                     /locus_tag="VQU19_000937"
     CDS             5459..5872
                     /gene="rpsL"
                     /locus_tag="VQU19_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HET2480201.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            5892..6362
                     /gene="rpsG"
                     /locus_tag="VQU19_000938"
     CDS             5892..6362
                     /gene="rpsG"
                     /locus_tag="VQU19_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HET2480202.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            6787..8868
                     /gene="fusA"
                     /locus_tag="VQU19_000939"
     CDS             6787..8868
                     /gene="fusA"
                     /locus_tag="VQU19_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HET2480203.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEEIRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            8972..13363
                     /locus_tag="VQU19_000940"
     CDS             8972..13363
                     /locus_tag="VQU19_000940"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HET2480204.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPAFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHDLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFESVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYRSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            13465..13728
                     /locus_tag="VQU19_000941"
     CDS             13465..13728
                     /locus_tag="VQU19_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HET2480205.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQALTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            13721..13999
                     /locus_tag="VQU19_000942"
     CDS             13721..13999
                     /locus_tag="VQU19_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HET2480206.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            14020..14172
                     /locus_tag="VQU19_000943"
     CDS             14020..14172
                     /locus_tag="VQU19_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480207.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALKEK"
     gene            14194..15435
                     /locus_tag="VQU19_000944"
     CDS             14194..15435
                     /locus_tag="VQU19_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HET2480208.1"
                     /translation="MVLPNFKENLGKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEEFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFKNAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            15445..15675
                     /locus_tag="VQU19_000945"
     CDS             15445..15675
                     /locus_tag="VQU19_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HET2480209.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAILGAMIVLAIFWRRGS"
     gene            15898..16620
                     /locus_tag="VQU19_000946"
     CDS             15898..16620
                     /locus_tag="VQU19_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HET2480210.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNNGQLAHVLLSPKRHVDKTYQAQVKGIMTQEDVETFIKGIPLKDFTC
                     QPARLEILSTDAEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            16837..18171
                     /gene="pepC"
                     /locus_tag="VQU19_000947"
     CDS             16837..18171
                     /gene="pepC"
                     /locus_tag="VQU19_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HET2480211.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALECRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQATVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
     gene            complement(18227..19138)
                     /locus_tag="VQU19_000948"
     CDS             complement(18227..19138)
                     /locus_tag="VQU19_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET2480212.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(19162..19965)
                     /locus_tag="VQU19_000949"
     CDS             complement(19162..19965)
                     /locus_tag="VQU19_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HET2480213.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            complement(19993..20982)
                     /gene="manX"
                     /locus_tag="VQU19_000950"
     CDS             complement(19993..20982)
                     /gene="manX"
                     /locus_tag="VQU19_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HET2480214.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            complement(21215..22234)
                     /gene="adhP"
                     /locus_tag="VQU19_000951"
     CDS             complement(21215..22234)
                     /gene="adhP"
                     /locus_tag="VQU19_000951"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HET2480215.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLTLAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            complement(22573..23385)
                     /locus_tag="VQU19_000952"
     CDS             complement(22573..23385)
                     /locus_tag="VQU19_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET2480216.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKRTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKEMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            23575..24993
                     /locus_tag="VQU19_000953"
     CDS             23575..24993
                     /locus_tag="VQU19_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HET2480217.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHAMIWILDALFILNYISMAL"
     gene            25046..25753
                     /locus_tag="VQU19_000954"
     CDS             25046..25753
                     /locus_tag="VQU19_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2480218.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVTGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            25848..26822
                     /gene="folP"
                     /locus_tag="VQU19_000955"
     CDS             25848..26822
                     /gene="folP"
                     /locus_tag="VQU19_000955"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HET2480219.1"
                     /translation="MMKILEGVTDMSSKANHAKTVICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDT
                     WKSQVAEAALAAGANLVNDITGLMGDEKMAHVVAKAGAKVVIMFNPVMARPQHPSSLI
                     FPHFGFGQTFTEKELADFETLPIEDLMVAFFERALARAAEAGITPENILLDPGIGFGL
                     TKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEESGFEVNPETELGFRNRDTAS
                     AHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            26824..28146
                     /locus_tag="VQU19_000956"
     CDS             26824..28146
                     /locus_tag="VQU19_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HET2480220.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGIPLVTGRIAPEALTVIDRIAEGKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALEDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLEQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            28127..28681
                     /gene="folE"
                     /locus_tag="VQU19_000957"
     CDS             28127..28681
                     /gene="folE"
                     /locus_tag="VQU19_000957"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HET2480221.1"
                     /translation="MDTQKIEAAVKMIIEAVGENANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            28724..29536
                     /gene="folK"
                     /locus_tag="VQU19_000958"
     CDS             28724..29536
                     /gene="folK"
                     /locus_tag="VQU19_000958"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HET2480222.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFEFYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIDKLRARGIYILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPTLKQPIRNLYDALKK"
     gene            complement(29581..29898)
                     /locus_tag="VQU19_000959"
     CDS             complement(29581..29898)
                     /locus_tag="VQU19_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HET2480223.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMYGRETILLPEEN
                     DLF"
BASE COUNT         8527 a         5841 c         7006 g         8700 t
ORIGIN      
        1 ttagaataat ttttcaaatt gaaggacaga gatagacaag gagaatcaca atggtagaat
       61 tgggaatttc aacatttggg gaaataacgg agcttgaagg gactggacaa acttacagtc
      121 atgctgaacg cattcgccag ttggtggcag agattgagct ggctgacaag gttggtttgg
      181 acgtatatgg gattggcgag caccatcggg cggattttgc agtatcagcc ccagagattg
      241 tcctggccgc tggggcagtc aataccaaga aaatccgttt gaccagtgca gtcagcattc
      301 tgtcaagcat ggatccgatt cgtttgttcc aacagtatgc cactatcgat gctttgtcaa
      361 atggacgagc ggagattatg gctggaaggg gctctttcac ggaatctttc cctctgtttg
      421 gttatgactt gaaagactac gactctcttt ttgatgagaa attagacttg cttcagttag
      481 tcaatgaaaa gaccaagtta gactggcaag gtcgattgac tcaaacgatt gctggtaaag
      541 aagtttatcc tcgtccagtt caggacaaat tgcccttgtg gatagctaca ggtggtcatg
      601 tcgaatcaac agtgaagatt gctcaggctg gtctaccgat tgtatatgct attattggtg
      661 gtaatccacg ttattttaaa aagttgattc aggcttatcg tgagattgga agcgaagcgg
      721 tccatgctga caaagacttg aaagtgggag cccattcttg ggggtggatt gcggaagatg
      781 gtgagcaggc ggtgaaagat tatttccatc cgactaagca agtggtggat gctatttcca
      841 aagaccgtcc gcactggcag gaattgcgtt atgagcaata tttggagcag gtagggtcaa
      901 atggcgccat gtttgttggc aatccagatc aggtggccga aaaattgatt cgcatgatag
      961 aggatttagg attggaccgc ttcatgcttc atctaccgct tggttctatg cctcatgacc
     1021 aggttctgag agctattgaa ctcttcggaa cacaagttgc acccaaagta cgagcttatt
     1081 ttgctatgaa agaggcttaa taaaaaatcc taatcaagtt tattaggaca acaaatattg
     1141 tacgaaaatt aatcccccga gctataatgc ttgggggatt tttctatagg agggctagtt
     1201 tagttctctt ttttattttt tagtaagaaa ccgagaccaa ggagcgcaag gaggctgatt
     1261 cctgcaaata ggagtttgtt ttcgttttta attcctgtat ttggaagttc agcttgtcta
     1321 tctggggttg caggtatatt tttcttgcta gagttttcta ccgattcgtt tcgaaccgct
     1381 tcttttacag atgatgcttg tgcttcttgt gctggttgtt cagcttgtga atcagctgta
     1441 gcttggctag gtttattttc cgcatcagct actttggtat ctggtttagt agaatcaggt
     1501 ctagcttctg gagctggatc ttgatgttca gggtgagaag cttcattttg atgttcaggc
     1561 ttggaagggg ttgagtctgg tttctcttct gcagttgact catggctagt tccattttga
     1621 gagactcgaa gaacagtagc tgtaagggca ttcaatttca agcctttttc agtccattca
     1681 agtcctttcg ggttggcaat tccgactgat cctgcttggt tttcatctgc caaaacttcc
     1741 gcatttctta gatgtgcaaa ggcagttccc aaattaaatt cgcgagcttt ttcatccgca
     1801 ttgacaaaga ctgcgtagat atcgccgttt ggagcagtga tttgatagcc aatcactaca
     1861 tcctcttttt ccacaccatt ttggcctggg acagtgatga ggtggacacg gtctttgata
     1921 tcttgaagac tcttaagtcg gaaggcatct gtagattgac gaagggcaat caaacctttc
     1981 atatagtcac ggctcttgac attttcagga taagctttac catctgtagc cttagtccag
     2041 tcaaacttgt tgactgcatc actagaatcg taagagtcat ggatgaagta aggatagtca
     2101 aatgggttgc cgtccttatc acgcaacaag tgagatttgt ttggaacctt atcctctgct
     2161 actggagtct tgtaggctgg gtcacggaat tgtttagtac gtccatattc ctgaccggag
     2221 tggataaatg gagttccttg agctgtcaag accatgagat ttccaagtcg taaacgacgg
     2281 tggatttcag catagttctc agccttgctt gggtcttttt tgatagactg ggcaatgatg
     2341 tcaaagaggg tcaagttatc atgggctgcg atgtattgga tgacatctcc agggctgtca
     2401 gcttcaaagt tagttggttg agcaatgaga tttttaaaga tggtgttgac atcacgcttg
     2461 ccacctgtga taaaggcagg ttgaccttcg tttggataac cagatttgag gttgttacgg
     2521 atgtcatctg aaaagacagc gacagtatcg gtatgtttca tccaatcttg gtcagcagct
     2581 ttagtaggca tgttttcatc accggcatag gttctccaac cttcaccaag catgatgagg
     2641 tttggattga gggcgcgtgc agccttgtaa gcttcttcga tagaagcggc gtcatggtct
     2701 cccatcatat cgaaacggaa gccatccact ttgtaggtat caactaggta tttgatagag
     2761 tcaattagga gccgtttggt catatggtgg gttgtcccca agcgtccacc accaaagcta
     2821 gttcgaggtg tgccatcggc atccataaag tggtagtagt ttggttccaa atcttcaaag
     2881 agatcgactt tggctgtgtg gttataaacg acatctagga tagctcccat accacgtttg
     2941 tggatttcgt tgatgaggtt tttaaattct gcgattcgtt tttctggatt cttaggatcg
     3001 cttgagtaca taccagtcaa ggagaagtag ttttgagggt catatcccca gttgtagttg
     3061 ctgttgcttg aagcgtagtc agacaagcgt tcatggtttt tcaattcatt gacaaagtag
     3121 taagacaaga ctggaaggag ctggatatgg gttacaccca agtctttgag atagtctagt
     3181 ttttcaatga aggcttcaaa agtcccaaat ggtttggtca agtcttttgc aatggcagga
     3241 tctgaagtga aatcacgcac atgagcttcg tagataacgg cgtcttcacg agtcttgaaa
     3301 ttgtgaatct taccataagt caagtcttga ggtccgagtt tagctggatc tacaaaggcg
     3361 gctttagcca ctttatgggc atcgtcaatc ttggaatcgt cgctattcca agcagcaaga
     3421 gatttagcgt aaggatcgag tgcaagaaca gttttacctt gacgctcgat ttggtattga
     3481 taatagtagc cagtgaaatc tgtgattccg agtttgtttg tgctgtctag agtttgtttc
     3541 caagttcctc tttccccttt ttcaagagcg acagttccaa ctactttgtc agggtcattc
     3601 ttgtcgtaga caacaacaga aaccttatca gcacttggtg accaaagggt caaatcaact
     3661 tgttttcctt cttcttttag gtcagctccc agtttgccat catagctgta tgtctcatct
     3721 ttcaggcgcc agcttgtttt ggtagtgaat tggtcggaat tgtagctaac agtataagga
     3781 tgttttgtgt cagagaaatc tccgctgtag gtcactttct taccagcttc atcgattgca
     3841 acatcggtaa tagttacctt gtttcctagg tgattagtga tgttggagtg tttgaggata
     3901 tcttcttttt tagcaccgac aagtgttgaa aagctacttt caatgctaga agtgcctacg
     3961 tgttgggctc ctgtcatacg gatatcatgg acatagtatg gatttgtgta aatcgattca
     4021 tcatcgtctt ttaggaaaat ttggctatga tttttcaaat ctgtgaactt ataattttct
     4081 ttacggattt tcacgtcgtc tccttgtttg ctctcatcta gtaataaaaa tccaaattct
     4141 cttgcggctt cattaagagg aatgtcgata tagcggccat atttgcctgt agccgtaaag
     4201 tctgttccgt caggccattg agcgctactt ggatttttca catctcccca gtaccagaga
     4261 gatttcttgt catagttgcc atctgtgcgg tagtagttga cgcgaacagt tcctgcaggc
     4321 tgtggctcgt aagagaaaac cttgtaatct tggtctaacc aagcttcgtt catttttgga
     4381 actagttttt ctacagattt atcgccggtt agattttttc cagctgtatt gttgatgagg
     4441 aagctaattt tcttggcttg ttctcccttt aatttgacat ctaggtaata gccgtagtca
     4501 tctttcttgg catccttgaa ggacaaagct ccgtttggcc agttttcaga tggtttttca
     4561 acatcgtccc aagtccatag tccttgagca tccttgtttt cttcaggaag ttttttgaca
     4621 tggatacgga agtagttatc ttcgatgggc tcttctgcct tagtttcagt tgttactgga
     4681 ctagtagaag tagttggctc acttgaacga tcttgtccag tttgtggtgc tggatcggct
     4741 gggcttgcag caggtttttc ttctgttttc tctagggaag cgtttgcatt tccaggtgaa
     4801 gaaatatcac tttcgttctt accagagcca gctgctgtat cagtaagagg ttgggcaagg
     4861 gtggttgtat ttctgttgtt gggttcgtta gtggttggtg tactttcgtc ggatgagata
     4921 gttggtgtag ccatggcaag caagacaagg cttgcgccga taaggacaga accagttcca
     4981 tttttgaggg aacggatgct gtagaccatt tttttctcag tgtgagatgg tgtttttctc
     5041 ataatgattc tccaatcaat aaatttctat atcagtatag catgtagtaa aacaatatgc
     5101 aagcgttttc tttgatttgt gaaagaaatt cttacttttg agaagttttc cgtactattt
     5161 tatatatcag tataaatgac ggagataaaa atgtcacgta agccaagccg tgttattagg
     5221 aagatgatgt gttctcagct atttttattc agaaattgat ctctaacatt accaataaaa
     5281 aagaaaaata tcttgacaag caagggaaaa ttttgttaca ataatagacg gtacttttta
     5341 cttttggtct ctcaagagtg tacagggacg tgctgacaaa tgttgcaaaa gtacacacag
     5401 atgatatctg tcaccaagtg tatcatcacc aaaaataaaa aaacacagga gaatgtagat
     5461 gcctacaatt aaccaattgg ttcgcaaacc gcgtaaatca aaagtagaaa aatctaaatc
     5521 accagctttg aacgttggtt acaatagtca taaaaaagtt caaacaaacg tttcttcacc
     5581 acaaaaacgt ggtgttgcaa ctcgtgttgg aacaatgaca cctaaaaaac ctaactcagc
     5641 ccttcgtaaa ttcgctcgtg tacgtttgag caaccttatc gaagttactg cctacatccc
     5701 aggtatcgga cacaacttgc aagagcacag cgtggtgctt cttcgcggtg gacgtgtaaa
     5761 agaccttcca ggggtacgtt accatatcgt ccgtggtgca cttgatactg caggtgttaa
     5821 cgatcgtaaa caaggccgtt ctaaatacgg tactaaacgt ccaaaagcat aaggaaaggg
     5881 gataaagaga aatgagtcgt aaaaatagag ctccaaaacg tgacgtattg ccagatccgc
     5941 tatacaattc acaactagtt actcgtctta tcaaccgcgt tatgcttgat ggtaaacgtg
     6001 gtactgctgc ttcaatcgtt tacggtgctt ttgagcaaat caaagaagct actggcaacg
     6061 atgcacttga agtatttgaa acagctatgg aaaacatcat gcctgtactt gaagtacgtg
     6121 cacgtcgtgt tggtggttct aactaccaag tcccagttga agttcgtcca gaacgtcgta
     6181 caacacttgg acttcgttgg ttggtaacaa tcgctcgtct tcgtggtgaa cacacaatgc
     6241 aagaccgtct tgcaaaagaa atcttggatg ctgctaacaa cactggtgca gcagttaaga
     6301 aacgtgaaga tactcaccgt atggctgaag ctaaccgtgc attcgcacac ttccgttggt
     6361 aagataggat gcgaaagcgt taagaaagtc ccagagaaaa tagggaatcg aagcaggttg
     6421 cggttgcaac caatgagatt catctttttc tccagacttt tagcttgagc tcaactaaat
     6481 catgatgcta ggaacggtaa ggatgcaagg taaaaatagg aaactgacgc agtattcgac
     6541 gaatacaagg agttttatct ttttcacgca gcatcccgtt ccagctcaca tcggctaact
     6601 aactttagcc cgggttcaaa ttagctaaat cgattagtat tagctataac tcagcttacc
     6661 atctcgtaag ttgaaaccaa caatagcatg aaaacattga gaacgggtag gtcctgccta
     6721 tccgttttta ttaaaatcgt gttataatag aatagaaatc aaaaataaat aggagaaaca
     6781 aacctcatgg cacgcgaatt ttcacttgaa aaaactcgta atatcggtat catggctcac
     6841 gtcgatgccg gtaaaacaac aactactgag cgtattcttt actacactgg taaaatccac
     6901 aaaatcggtg aaactcacga aggtgcgtca caaatggact ggatggagca agagcaagaa
     6961 cgtggtatca cgatcacatc tgctgcgacg acagctcaat ggaacaacca ccgcgtaaac
     7021 atcatcgaca caccaggaca cgtggacttc acaatcgaag tacaacgttc tcttcgtgta
     7081 ttggatggtg cggttaccgt tcttgactca caatcaggtg ttgagcctca aactgaaaca
     7141 gtttggcgtc aagcaactga gtacggagtt ccacgtatcg tatttgccaa caaaatggac
     7201 aaaatcggtg ctgacttcct ttactctgta agcacacttc acgatcgtct tcaagcaaat
     7261 gcacacccaa tccaattgcc aatcggttct gaagatgact tccgtggtat cattgacttg
     7321 atcaagatga aagctgaaat ctatactaac gaccttggta cggatatcct tgaagaagac
     7381 atcccagctg aataccttga ccaagctcaa gaataccgtg aaaaattgat tgaagcagtt
     7441 gctgaaactg acgaagaatt gatgatgaaa tacctcgaag gtgaagaaat cactaacgaa
     7501 gaattgaaag ctggtatccg taaagcgact atcaacgttg aattcttccc agtattgtgt
     7561 ggttcagcct tcaaaaacaa aggtgttcaa ttgatgcttg atgcggttat cgactacctt
     7621 ccaagcccac ttgacatccc agcaatcaaa ggtattaacc cagatacaga cgctgaagaa
     7681 attcgtccag catctgacga agagccattt gcagctcttg ccttcaagat catgactgac
     7741 ccattcgtag gtcgtttgac attcttccgt gtttactcag gtgttcttca atcaggttca
     7801 tacgtattga atacttctaa aggtaaacgt gaacgtatcg gacgtatcct tcaaatgcac
     7861 gctaacagcc gtcaagaaat cgacactgtt tactcaggtg atatcgctgc tgccgttggt
     7921 ttgaaagata ctacaactgg tgactcattg acagatgaaa aagctaaaat catccttgag
     7981 tcaatcaacg ttccagaacc agttatccaa ttgatggttg agccaaaatc taaagctgac
     8041 caagacaaga tgggtatcgc ccttcaaaaa ttggctgaag aagatccaac attccgcgtt
     8101 gaaacaaacg ttgaaactgg tgaaacagtt atctcaggta tgggtgaact tcaccttgac
     8161 gtccttgttg atcgtatgcg tcgtgagttc aaagttgaag cgaacgtagg tgctcctcaa
     8221 gtatcttacc gtgaaacatt ccgcgcttct actcaagcac gtggattctt caaacgtcag
     8281 tctggtggta aaggtcaatt cggtgatgta tggattgaat ttactccaaa cgaagaaggt
     8341 aaaggattcg aattcgaaaa cgcaatcgtc ggtggtgtgg ttcctcgtga atttatccca
     8401 gcggttgaaa aaggtttggt agaatctatg gctaacggtg ttcttgcagg ttacccaatg
     8461 gttgacgtta aagctaagct ttatgatggt tcatatcacg atgtcgactc atctgaaact
     8521 gccttcaaga ttgcggcttc actttccctt aaagaagctg ctaaatcagc acaaccagct
     8581 atccttgaac caatgatgct tgtaacaatc actgttccag aagaaaacct tggtgatgtt
     8641 atgggtcacg taactgctcg tcgtggacgt gtagatggta tggaagcaca cggtaacagc
     8701 caaatcgttc gtgcttacgt tccacttgct gaaatgttcg gttacgcaac agttcttcgt
     8761 tctgcatctc aaggacgtgg tacattcatg atggtatttg accactacga agatgtacct
     8821 aagtcagtac aagaagaaat tattaagaaa aataaaggtg aagactaatc cgtcctcact
     8881 ctagaaggaa gtcacttagt ggcttccttt tgtctttaga aaatacctct aaatatggta
     8941 aaatagtaga agaataatgt gaggaaaatg aatgtcaaat agttttgaaa ttttgatgaa
     9001 tcaattgggg atgcctgctg aaatgagaca ggctcctgct ttagcacagg ccaatattga
     9061 gcgagttgtg gttcataaaa ttagtaaggt atgggagttt catttcgtat tttctaatat
     9121 tttaccgatt gaaatctttt tagaattaaa gaaaggtttg agcgaagaat tttctaagac
     9181 aggcaataaa gctgtttttg aaattaaggc tcggtctcaa gaattttcaa atcagctctt
     9241 gcagtcctac tatagggagg ctttctctga aggtccatgt gctagtcaag gttttaagtc
     9301 cctttatcaa aatttgcaag ttcgtgctga gggtaatcag ctatttattg aaggatctga
     9361 agcgattgat aaggaacatt ttaagaagaa tcatcttcct aatttagcca aacaacttga
     9421 aaagtttggt tttccaactt ttaactgtca agtcgagaag aatgatgtcc tgacccaaga
     9481 gcaggaagag gcctttcatg ctgaaaatga gcagattgtt caagctgcca atgaggaagc
     9541 gctccgtgct atggaacaac tggagcagat ggcacctcct ccagcggaag agaaaccagc
     9601 ctttgatttt caagcgaaaa aagctgcagc taaacccaag ctggataagg cggagattac
     9661 tcctatgatc gaagtgacga cagaggaaaa tcgtctggta tttgaagggg ttgtttttga
     9721 tgtggagcaa aaagtgacta gaacaggtcg tgttttaatc aactttaaaa tgacggacta
     9781 tacttcaagt ttttctatgc aaaagtgggt taaaaacgag gaagaggccc agaagtttga
     9841 cctcatcaag aagaattctt ggctccgagt tcgagggaat gtggagatga ataacttcac
     9901 acgcgatttg actatgaacg tacaggatct gcaggaagtt gttcactatg agcggaagga
     9961 tttgatgcca gaaggtgagc gtcgggttga gtttcatgct catactaaca tgtcgactat
    10021 ggatgctttg ccagaggtcg aagagattgt tgcaacagct gctaagtggg gacacaaggc
    10081 ggttgctatc acggaccatg ggaatgtcca gtcctttcca catggctata aggcggctaa
    10141 gaaagcggga atccagctga tctatgggat ggaagccaat atcgtggagg accgtgtccc
    10201 tatcgtctat aacgaagtgg agatggactt gtcagaagca acctacgtgg tctttgacgt
    10261 ggaaacgacg ggactttcag ctatctataa tgacttgatt caggttgcgg cttctaagat
    10321 gtacaagggg aatgttattg ctgaatttga tgaatttatc aatcctgggc atcccttgtc
    10381 agcctttact acagagttaa ctggaattac agatgatcat gtcaaaaatg ccaaaccact
    10441 agaacaagtt ttgcaagaat tccaagaatt ttgcaaggat acggtcctag ttgcccacaa
    10501 tgctaccttt gacgttggct ttatgaatgc taattatgag cggcatgatc ttccaaagat
    10561 tagtcagcca gttattgata cgctggagtt tgctagaaac ctctatcctg agtataaacg
    10621 ccatggtttg gggcctttga ccaagcgttt tggtgtggcc ttggaacatc accacatggc
    10681 caactacgat gcggaagcga ctggtcgtct gcttttcatc tttatcaaag aggtagcaga
    10741 aaaacatggt gtgaccgatt tagctagact caacattgat ctaatcagtc cagattctta
    10801 caaaaaagct cggatcaagc atgcgaccat ctatgtcaag aatcaggtag gtctaaaaaa
    10861 tatctttaag ctggtttcct tgtctaatac caagtatttt gaaggagtgc cacggattcc
    10921 gagaacggtt ctagatgccc atcgagaggg cttgatttta ggttcagcct gttcagaggg
    10981 tgaagttttt gacgtggtcg tttctcaagg tgtggatgcg gcggttgagg tggccaagta
    11041 ttatgatttt atcgaggtca tgccaccggc tatctatgca cccttgattg ccaaagagca
    11101 ggtcaaggat atggaggaac tccagaccat tatcaagagt ttgatagagg ttggagaccg
    11161 ccttggcaag cctgttctgg ctacgggaaa tgttcactat atcgaaccgg aagaagagat
    11221 ttatcgtgaa attatcgtcc gtagtttggg acagggtgcg atgattaatc gaactatcgg
    11281 tcatggtgaa catgcccaac cagcaccact tccaaaggct cattttcgaa cgactaatga
    11341 gatgttggat gaatttgcct ttttgggaga ggaactggct cgtaaactgg ttattgaaaa
    11401 caccaatgcc ttggcagaaa tatttgaatc cgttgaagtc gttaagggtg acttgtatac
    11461 gcctttcatc gacaaggctg aagaaacagt tgctgagttg acctataaga aagcttttga
    11521 gatttatgga aatccgctgc cagatattgt tgatttgcgg attgaaaaag aattaacatc
    11581 catactgggg aatggatttg ctgtgattta tctggcatcg cagatgctgg tgcaacgttc
    11641 taatgaacgg ggttatttgg ttggttctcg tgggtctgtc ggatctagtt tcgttgcgac
    11701 catgattggg attacggagg tcaatcctct ctctcctcac tatgtctgtg gtcagtgtca
    11761 gtacagtgag tttatcacag atggttcgta cggttcagga tttgatatgc cccataagga
    11821 ctgtccaaac tgtggtcaca aactcagtaa aaacggacag gatattccgt ttgagacctt
    11881 ccttggtttt gatggggata aggttcctga tattgacttg aacttctcgg gagaagatca
    11941 gcctagcgcc cacttggatg tgcgtgatat ctttggtgaa gaatatgcct tccgtgcggg
    12001 aacggttggt acggtagctg ccaagactgc ctatggattt gtcaagggtt acgagcgaga
    12061 ttatggcaag ttttatcgtg atgcagaagt agaacgcctc gctcaaggag cggcgggtgt
    12121 caagcggaca acaggccaac acccgggggg aatcgttgtt attccgaact acatggatgt
    12181 ctacgatttt acgcctgtcc agtatccagc agatgatgtc acggctgaat ggcagaccac
    12241 tcactttaac ttccacgata tcgatgagaa cgtcctcaaa ctcgatgtac tgggacatga
    12301 tgatccgacc atgattcgaa aacttcagga tttgtctggt attgacccta ataaaattcc
    12361 tatggatgac gaaggcgtga tggcactctt ttctgggact gatgtactag gggtaacacc
    12421 tgaacaaatt ggaacgccta cgggtatgtt ggggattcca gagtttggaa caaatttcgt
    12481 acgtggaatg gtagacgaaa cccatccgac aacctttgcg gaattgcttc agctgtctgg
    12541 tctgtcccac ggtactgacg tttggttggg gaatgctcag gatctgatta agcaaggaat
    12601 agcggaccta tcgactgtta tcggttgtcg ggacgacatc atggtttacc tcatgcatgc
    12661 gggtctggaa cctaagatgg cctttaccat tatggaacgg gtacgtaagg gtttgtggct
    12721 aaagatttca gaagaggaga gaaatggcta tatcgaagcc atgaaggcta ataaggtgcc
    12781 agagtggtat atcgaatcct gtgggaaaat taagtacatg ttccctaagg cccatgcggc
    12841 agcctacgtt atgatggcct tgcgtgtagc ttacttcaag gttcaccatc ctatttatta
    12901 ctactgtgct tacttctcca ttcgtgctaa ggcttttgat atcaagacca tgggtgcggg
    12961 cttggaggtc atcaagcgca gaatggaaga aatctctgaa aaacggaaga acaatgaagc
    13021 ctctaatgtg gaaatcgatc tctatacaac tcttgagatt gtcaatgaga tgtgggaacg
    13081 aggtttcaag tttggtaaat tagatctcta ccgtagtcag gcgacagagt tcctcatcga
    13141 cggggatacc cttatcccac catttgtagc aatggatggt ctgggagaga acgttgccaa
    13201 gcaactggtg cgggcgcgtg aagagggaga attcctctct aaaacagaac tacgcaagcg
    13261 tggtggactc tcatcaacct tggttgaaaa gatggatgag atgggtattc ttggaaatat
    13321 gccagaggat aaccagttga gtttgtttga tgagttgttt taaaaaattg cttaataatc
    13381 tattaaaaga ggctaacgta tatccaatag atttacatta gctttctttt ttgttaaaat
    13441 agtctatgga aagagggtga gagtatgtca aagatgagta taagcatccg tctggatagt
    13501 gaggttaagg agcaggccca acaggtgttt agtaatctgg gaatggatat gacaacagct
    13561 attaatattt tccttcgtca ggcaattcaa tatcagggat taccttttga tgttagacta
    13621 gacgaaaatc ggaagttgct ccaagcgtta acggatttag accaaaatcg taatatgagc
    13681 cagtcttttg aatcagtctc agatttgatg gaggacttac gtgcttaaga ttcgttatca
    13741 taaacagttt aaaaaagatt ttaagttggc tatgaagcgt ggtttgaagg cagaattatt
    13801 agaagaagtt ttgaattttc tggttcaaga aaaagaacat cctgccagat atcgtgatca
    13861 ttcattgacg gcatccaagc attttcaagg agttcgtgaa tgccataccc agccagattg
    13921 gcttttggtt tataaagtag acaagtcgga attgatttta aatttgctga ggacaggcag
    13981 tcacagtgat ttattttaat ctattttaag ggggttctca tgaaactaag aatatttgcg
    14041 gaagataagc cggctaagaa ggtatttgaa tatcaattag aacttgctga tcgtacaatt
    14101 cttctatcga cagcactctt gtcaggtgct attgctttag caggaatctt ttctgctttg
    14161 aaagaaaaat aaaaatagaa aagagaaaac agaatggttt taccaaattt taaagaaaat
    14221 ctaggaaaat atgcgaaatt gttggttgcg aacggaatta acgtgcaacc tggtcacact
    14281 ttggctctct ctattgatgt ggagcaacgt gaattggcac atctaatcgt gaaagaagct
    14341 tatgccttgg gtgcgcatga ggtcatcgtt cagtggacag atgatgtgat taaccgtgag
    14401 aaattcctcc atgccccgat ggagcgtttg gacaatgtgc cagaatacaa gattgctgag
    14461 atgaactatc ttttggagaa caaggctagc cgtcttgggg ttcgttcatc tgatccaggt
    14521 gccttgaacg gagtggacgc tgacaagctt tcagcttctg ctaaagctat gggacttgcc
    14581 atgaagccta tgcgtatcgc aactcaatct aacaaggtta gctggactgt agcagccgct
    14641 gctggacttg agtgggctaa gaaagtcttc ccaaatgctg cgagcgacga agaagcagtt
    14701 gatttccttt gggatcaaat cttcaaaact tgtcgtgtct acgaagcaga tcctgttaag
    14761 gcttgggagg aacatgcagc cattctcaag agcaaggccg atatgcttaa taaggagcaa
    14821 ttttcagccc ttcactacac agcgccagga acagatttaa cacttggttt gccaaagaac
    14881 cacgtttggg aatcagctgg tgctgtcaat gcacagggcg aagaattctt gccaaatatg
    14941 ccgacagaag aggtcttcac agcgcctgac ttccgtcgtg cagatggtta tgtcacttct
    15001 acaaaaccgc ttagctacaa cggaaatatc attgaaggca ttaaggtgac ctttaaggat
    15061 ggacaaatcg tagatatcac tgctgagaag ggtgatcagg ttatgaaaga ccttgtcttt
    15121 aaaaatgcgg gtgcgcgtgc cttgggtgaa tgtgccttgg taccagatcc aagtccaatt
    15181 tctcagtcag gcattacctt ttttaacacc cttttcgatg aaaatgcgtc aaaccacttg
    15241 gctatcggtg cagcctatgc gactagcgtt gttgatggag cggagatgag cgaagaggag
    15301 cttgaagctg cagggcttaa ccgttcagat gttcacgtag actttatgat tggttctaac
    15361 caaatggata tcgatggtat tcgtgaggat ggaacgcggg tacctctttt ccgtaatggg
    15421 aattgggcaa attaaggaga taatatgtta ggaagtatgt tcgttggtct cctagtggga
    15481 tttttagcag gtgctatgac caatcgtgga gagcgaatgg gatgttttgg aaaaatgttt
    15541 ctcggttgga tcggagcctt tctaggtcac ttgctctttg gaacttgggg gccagtttta
    15601 tcaggaacag ctattatccc agcgatttta ggagccatga ttgttttagc tattttttgg
    15661 agacgaggaa gttaatttcc taaatctgat actcaatgaa aatcaaagag caaactagga
    15721 aactagccgc aggttgctca aagcactgct ttgaggttgc agatagaact gacgaagtca
    15781 gtaacatata tacggcaagg cgacgttgac gcggtttgaa gagatttttg aagagtatga
    15841 aacgaaaagg aggttggtca ttgtactagc ctccttttga tatgatataa tagttctatg
    15901 agattagata aatttttagt tgcctgtgcg gtgggaagtc ggactgaggt caaaaacttg
    15961 ctcaaggctg ggcgcgtgac tgtaaatggt aaaaaagaaa aatcagctaa attgcagatt
    16021 gatgaaaaaa tagatgagat tcgctttgat gggcaagtgt tggagtatga agagtttgtc
    16081 tactacatga tgaacaagcc caaaggagtt atctcagcga ctgaggatcc caagcacaga
    16141 accgttctgg acttgttgga tgacttggcg cggagtaagg aagtttttcc agtaggacgc
    16201 ttggatattg acacgcatgg tcttttgctc ttgaccaata atggtcagct ggctcatgtt
    16261 cttctttcgc ccaagcgtca tgtggacaag acttatcagg ctcaggtcaa gggaattatg
    16321 acccaagaag atgtggagac atttatcaag ggcattccgc tcaaagactt tacctgtcag
    16381 cccgctagac tggagattct ttccacagat gcagaaaaga atcagagcca aatccgtgtg
    16441 accattgcag aagggaagtt tcatcagatc aagcgtatgg tgggctactg tggcaaggaa
    16501 gtggtggact tgcaacgatt gactatggga actttagtat tagatgagaa cctggaacga
    16561 ggggaatggc gtcgcttgac caaggaagaa ttagaaattc tccgcgctaa tattatttaa
    16621 tttagtttaa tactcaatga aaatcaaaga gcaaactagg aaactagccg caggctgtac
    16681 ttgagtacgg caaggcgacg ttgacgtggt ttgaagagat tttcgaagag tataaattcg
    16741 aaaaaggtga gggacaatgt cctcgccttt tatgtttttt agttgcttcc tttgtgaaaa
    16801 gagttataat agactgtaga ataaaaggag gaatctatga acgcgattca agaatcattt
    16861 actgataaac tatttgccaa ctatgaagca aatgtaaaat accaagcgat tgaaaatgct
    16921 gccagccaca acggaatttt tgcagctctg gaatgtcgcc aaagccatgt agacaacaca
    16981 cctgttttct cattggattt aaccaaggac aaggtcacta accagaaagc gtctggtcgt
    17041 tgctggatgt ttgcggctct caacaccttc cgccacaaac tcatctcgca atacaaattg
    17101 gagaactttg agttgtcaca agcccacact ttcttctggg ataagtatga gaaatcaaac
    17161 tggttcttgg agcaagtcat tgcgacttca gaccaagaat tgactagccg caaggttagc
    17221 ttcttactcc aaacacctca acaagatggc ggtcaatggg atatggtcgt ttccctcttt
    17281 gaaaaatacg gtgtcgtgcc taagtcagtt tatcctgagt ctgtttcatc tagcagcagt
    17341 cgtgagctaa atgcgatcct taataaattg cttcgtcaag atgctcaaat cttgcgtgat
    17401 ttgcttgttt ctggtgcaga tcaagcgact gttcaagcta agaaagaaga cctcttgcaa
    17461 gaaatcttta actttcttgc tatgtcatta ggacttccac cacgcaagtt tgactttgct
    17521 tatcgcgata aagataacaa ctataaaagt gaaaaaggaa tcacaccaca agagttttac
    17581 aagaaatatg tcaatcttcc tttagaagac tacgtttctg ttatcaatgc tccaactgct
    17641 gataaacctt acggaaaatc ttacacagtt gagatgttgg ggaatgtggt tggtagccgt
    17701 gcagttcgct acatcaacgt tccaatggag cgcttgaaag aattggcgat tgcccaaatg
    17761 caagcaggtg agactgtttg gtttggttct gatgtcggcc agctcagcaa ccgtaaggct
    17821 ggcatccttg cgacagatgt ttatgacttt gaatcaagca tggacattaa acttactcaa
    17881 gacaaggctg gacgtttgga ctatagcgaa agcttgatga cccacgccat ggtcttgaca
    17941 ggtgttgact tggacgaaaa tggtaaatca accaagtgga aggttgaaaa ctcatgggga
    18001 gacaaggtcg gtacagatgg ttactttgtt gcctcagacg cttggatgga cgaatacaca
    18061 taccaaatcg ttgttcgtaa ggaattgctg acagcagaag aacaagctgc ctatggagca
    18121 gaaccaatcg tacttgcacc atgggatcca atgggagcct tggctgaata aaagcataga
    18181 aaaaaggaat cagattttag aacctggttc ctttttagtt gcttgattac atgatgtgaa
    18241 gaacatgtgc cacaataccc actgcgaaga gggcaaggat aatagtgatt ggagatactt
    18301 ttttcttaag taagtacatg caaagtaaag taaggagtag tcctgataat ccaggaatca
    18361 acatatccaa gttttgttgg aaagtagtaa ctttttcagg agtttgagac aatccttgtc
    18421 ctacttgtgc gaatgcttct tggatacctt tagacccttc tggcaattta tcccaatgga
    18481 tataagcctt ttcatctagt tgaactttag aaacatcgaa agcaaattta atatttaccc
    18541 agcgttgaac aaggacagca agaatgaaca tcccaaggat agaagctcct ttagtgatat
    18601 cttgaaggat accaccagac atatctttag tgatttctga tccagccttg tatccaatct
    18661 cttgaacata ccacaagaat gacatacgaa tcaagttcca tgcaacaaag aagaggagtg
    18721 gccccaagat attgccagta agggcaagtg aagcaccgag agatccaagg attgggcgta
    18781 ctgtaaacca gaatactggg tcaccgatac cagcaagagg tcccatcata ccgattttaa
    18841 ccccttggat agcagcgtca tcgatttcca caccgttagc acgttcttct tcaagcgcaa
    18901 gagtaacccc catgactgga gcagctacgt atggatgagt gttgaagaac tcaaggtgac
    18961 gctcaagagc agcgatttga tcttcttttt tagtatagag ttttttgata gctggaatga
    19021 gtgtataagc ccagcccaag ttttgcatcc gttcaaagtt ccaagaccct tgtaagaagg
    19081 ttgaacgcca ccaaactttt ttacgatctg atttagttaa ttgaagtttt tcagtcatga
    19141 tgttttcagt cctttcttat cttagtagtc ttctaggata tcgccgattg ggtcgttaga
    19201 agttgcggct cctccgccac catttccacc agttttagaa aggtgaaggt agataagagc
    19261 gatagcaaca ccgatagcac cgaatccgat tagagtaata tctgacacag cagcaagaac
    19321 gaaaccaaga gcgaagaatg gccatacttc acgagttgcc atcatgttga taaccatggc
    19381 gtaaccaacg gcaacgacca taccaccacc gatagccata ccatctttga gccagtctgg
    19441 catggcacta aggatacttt gtacagtttc agttggtacc ataaggagaa gagctgcagg
    19501 aagcgcgata cgaagtcctt ggaaaagtag cgcaatgaaa tgagcacgct ccacagcgcc
    19561 gaagtcacct tttttagcgg cagcatcagc agtgtgaacc aatccaactg aaattgtacg
    19621 aacaatcata gttaagaata gaccagctac ggcaagaggg atagcaaccg cttgggcaac
    19681 accgatacca gtcttggtaa agtcaccacc aagaaccatg ataatggcag cagcgacaga
    19741 agcaagtgca gcatcaggag cgatagcagc accgatattt gaccaaccaa gggcaatcat
    19801 ttgaagcgat ccaccgagga taatccctgc ttccaagtga cctgttacaa gcccaataag
    19861 ggtacaggct acaagtggtt ggtgaaattg gaactggtcg aggatgcctt caagacctgc
    19921 aaagaaggct acaacgacta ctaaaaccat agaaataata gacatgttta aaatcctttc
    19981 ataaataatg gcttatttga cattggcttt gttaatcaag tcaaacaaat cttttttaga
    20041 atcatttggt actttacgga catcaaattc aacacccaag tcacgcattt tttcaaatgt
    20101 agcaacatct tctttgtcca tagacaaaac ggtattgacc aatgttttac ctgttgagtg
    20161 agccatagaa ccaacgttaa gagtcttgat tggcacgccg ccttcgatgg cacgaagggc
    20221 atcttgaggt gtttcaaaca agataagggc atgtgtttct ccaaaacgtg ggtcttttga
    20281 aatctcaatc agtttttgaa ttggaaccac gttagccttg acattacctg gagctgcttg
    20341 tttaatcaat tctttacgaa ggtcgtcttt agccacgtta tctgaagcaa cgatgatacg
    20401 atttgctttt gaatctggag tccaagcagt tgcaacctga ccgtgaagta gacgtgtgtc
    20461 aagacgggca agattgattt tcaatttacc gtctccgata acagttcctt ctgggatagc
    20521 agtttgggca actggagcag ctgcagcgct tgcaacttct tcaactggat ttagctcttc
    20581 tggaagagct ttgatgccat ctttggcttc tttaatgata ttagcagcga ctttttctac
    20641 acctgcagca gcgtccatga ggcgctctgt gtaggcttga atcaacatcg gtaagttaag
    20701 tcctgtgatg atggcaaact tacgctcagg attttctccc atcacgcgac tagcttggtt
    20761 aaatggagaa ccactccaaa ggtcagccaa aactagaacc tcatcttctg cgtcaaatgc
    20821 agcaacagcg ttattaaact tagcgtatag atcatcagga ccttcatttg gcataaaggt
    20881 cacaacttga accttttctt gttcaccaaa gatcatagat cctgactgat gaatacccgc
    20941 agcaaattcg ccgtggctcg caataatgat tccgatactc attattgtca ttcctccttt
    21001 tttgttttag ttttcattta agaaaacttt aagactgttt aagtataaac cgttttcata
    21061 aaaaaagcaa ctatttatca taaaaaatta aaaaattttt atttttgtat gttgatatgt
    21121 tgagtttttg aggagtaatc ttgaattctt atttaaaatt taatataaaa aagttggaag
    21181 aagcttccaa cttttaaaat aggtttctat taaattagtg ggtgaagtcg agtaccatac
    21241 gtccttggat ttggcctttt tccatttcgt cgaaaatggc aacagcatct tctactggac
    21301 gtttttgaac aactgggact accagacctt ctgcaccaaa ttggaaggct tcttctaagt
    21361 ctttacgagt tccgacaaga gaaccgatga cttggattcc atcgaggact gttttaacga
    21421 tgctgagttc catcatttca gaaggaagac caacagcgac gacgcgacca ccagcacgaa
    21481 tggagtcaac agcctggttg aaggcaactt tagacacagc agttacgaca gctgaatgag
    21541 ctcctccatc agttttttct ttaatgagtc cagctacatc ttcaacttcg aggccgttaa
    21601 tcacaatgtc agcgcctact tcttttgcaa gggtaagttt gtcattgttg atatcgactg
    21661 cgataacatg agcattgaat acttttttag cgtattgaac agcgaggtta ccaagtccac
    21721 cagcaccgta aagaacaacc cattggcctg gttcaacttt tgcttctttg atagctttat
    21781 aggttgttac tccagcacat gtgatagaag aagcttgggc tggatcaagt ccgtcaggaa
    21841 ctttgacagc atagtcagca gttacgatac attgttcagc cataccaccg tctactgagt
    21901 agccagcatt tttcactgta cggcaaaggg tttcgcgacc agttgtacag tattcgcaag
    21961 tgccacatcc ttcaaagaac caagcaacgc tgacgcggtc accgacttta aggcttttca
    22021 catctggagc aatctcttta acgataccga taccttcgtg cccaagaaca cgtcctggga
    22081 cttgaccaaa gtcaccatga gcaacgtgga ggtcggtgtg gcaaacgcca cagtattcaa
    22141 cttctacaag tgcttcccca gtttcaagtg gacggagtac tttttcttca atagcaacac
    22201 cagtgctttc tggatttaca acaacagctt tcatagctat cctccttgat attgaccgag
    22261 aacagggaca acgggactgg attgattttt tgtcaacaga gtcgagtgtg acgagctctc
    22321 ttgtatttat atgtgaagta tatcacaaaa ggaagccttt tccaaggttt tggagacaaa
    22381 aagtagaaca atcgattaac tggttgatga gactgtgaaa agagcacaaa gaccagcttg
    22441 caagctggtc atactcttcg aaaatctctt caaaccacgt cagcttcatc tacaacctca
    22501 aagcagtgct ttgagcaacc tacggctagc ttcctagttt gctctttgat tctcattgag
    22561 tatcagtata ggttataaga ataagtcttg tagggttttg gcaaccccat cttggtcgtt
    22621 ggtaagggaa atttgctcat ctgcataagg gagtagctct ggattggcat ttttcatggc
    22681 ataacccttc ccagcaaaag cgagcatttc ggtatcattg tgttcatctc caaaggcaat
    22741 caaatctttt ttgtcacgat tcattatctt gagcaagtag tccaaagcaa aggccttgtt
    22801 gacacctttt ggggtacatt caaggatatt gagcggacct ccccaggtat tgatagaaag
    22861 ttgatgctgg tagaaggcgt tcatttcttt tgccaaggca tatttgtcac tggctctggt
    22921 ctgcaagagg atacagttag ggtccttggt caccaattca ggctggaatt gatcttcagg
    22981 ctggaaagct tctacaccaa atagtttggg attggcaatt tcttcattgg gatttgtaat
    23041 gtagaatttt ttacgatatt ctccagcgat aaaatcggct tgaatgtcct ctgaacgttg
    23101 aaccatatct agcagatatt ttttgtctac agtcaaacac ttttcaaaat cccaaacttg
    23161 gtctggtaaa tgagtaaggg atccgttgaa gttaatcata ggagtgtcta agcccagttc
    23221 acggtaaaaa tcttttgaca tacggtaagg gcgacctgtc gtaataataa cctgatggcc
    23281 tttttcagca acttttttga tggttctttt ggtaaagtca gaaatttgac tgtctgagtt
    23341 gagcagggtt ccatccaggt caactgcaat aatttttttc gtcatatgga cctttctagt
    23401 gtgttttcag ataagatgtc ttctattata acagaaagca ggcagaaaag cagattccaa
    23461 acaaaaaatg aaattggatt aatttcttaa acaaatcaaa caaagacatt gaaaaagtga
    23521 atgataaatg atataattct attattgttc gtaaaaatta aaaggagatt gatgatggac
    23581 aaattattta aactaaaaga gaacggtaca gacgttcgta cagaggttct cgctggttta
    23641 acaactttct ttgcaatgag ctatattctc tttgtaaacc cacaaatact ttcacaaaca
    23701 ggaatgcctg ctcagggcgt cttcctagcg acgattattg gtgcagtagc gggtaccttg
    23761 atgatggctt tttatgctaa cttaccttat gcccaagcac caggtatggg actcaatgcc
    23821 ttctttacct ttacagttgt attcgggctt ggttattctt ggcaagaagc cctagctatg
    23881 gtcttcatct gtgggattat ttcattgatt attaccttga caaatgttcg taaaatgatc
    23941 attgaatcga ttcccaatgc tcttcgctca gctatttcag ctggtatcgg tgtcttcctt
    24001 gcctatgtag ggattaagaa tgctggactt ttgaaattca cgattgatcc aggcaactat
    24061 actgttgtag gagaaggggc tgacaaagct caagcaacga ttgcagcaaa ctcttcagca
    24121 gttccaggat tggtcagctt taataatcca gctgttttag tggctcttgc aggacttgcc
    24181 attactatct tctttgtcat caaagggatt aaagggggaa ttattctctc tatcttgaca
    24241 acaactgttc ttgctattgc agttggtttg gttgatttgt ctagtatcga ttttgctaat
    24301 aaccatgttg gtgcagcttt tgaagatttg aagacaatct ttggtgcagc tcttggttca
    24361 gaaggtttgg gagctttggt ttcagataca gctcgcttgc ctgaaactct gatggccatt
    24421 cttgccttct cattgacaga tatttttgac acaattggta ccttgatcgg tacaggtgaa
    24481 aaagttggta ttgtagcgac aaatggtgaa aatcaccaat cagccaaatt ggataaggct
    24541 ctttactctg atttgattgg aacgacagtc ggtgccattg caggtacttc aaacgtaacg
    24601 acttatgttg agtctgctgc tggtatcggt gcaggtggac gtactggttt gacagccttg
    24661 gttgtagcta tctgttttgc gatttcaagc ttctttagcc cacttctagc gatcgtacca
    24721 acagcggcta cagctccaat cttgattatc gttgggatta tgatgcttgg tagcttgaaa
    24781 aatatccatt gggatgatat gtctgaagca gttcctgcct tcttcacatc tatctttatg
    24841 ggattcagct actctatcac tcaagggatt gcagttggtt tcttgactta cactttgact
    24901 aagcttgtca aaggtcaagt taaagatgtt catgccatga tttggatttt ggatgccttg
    24961 tttatcctta actacatcag catggcctta taatagaatg acccaggggg atttcccccc
    25021 ttttttaata caaaggagat aggtgatgaa agagaaaaat atgtggaaag aattgttgaa
    25081 tcgtgcaggc tggattttgg tctttttact tgccgtcctt ttatatcagg ttcccctagt
    25141 ggttacctct attttgactt taaaagaagt agccctgcta cagtcagggc tgatagttac
    25201 tggcctttca attgtggttc tggctctatt tattatggga gctcgtaaaa ccaagttagc
    25261 tagttttaat ttttcttttt ttagagctaa agatttggca cgtttgggct tgagttattt
    25321 agttattgtc gggtcaaata tacttggttc tatcttgttg caactgtcaa atgagacgac
    25381 aacagctaac cagtctcaga ttaacgatat ggttcagaat agttctctga tttctagctt
    25441 cttcttgcta gccttgcttg ctccaatttg tgaggaaatc ttgtgccgtg ggattgttcc
    25501 taaaaagatt ttccgaggca aggagaactt gggatttgta gtcggtacga ttgtgtttgc
    25561 tttattgcat caaccaagta atttaccttc tttattgatt tatggaggta tgtcgacagt
    25621 tctatcttgg acggcctaca agacccaacg tttggaaatg tcgatcttgc ttcacatgat
    25681 tgttaatggg attgctttct gtttgttggc tcttgtggtg attatgagtc ggacattagg
    25741 aatttctgtg taaaagtttt tatgtaggaa ccgacctctt tctactaggg aaagatgaat
    25801 gcaatcgtgt ccatcttttt ctttttatgg taaaatagaa aaataatatg atgaaaatcc
    25861 ttgagggagt gaccgatatg tcaagtaaag ccaatcatgc aaagacagtt atttgcggaa
    25921 ttatcaatgt aaccccagac tccttttcgg acggtggtca attttttgct cttgagcagg
    25981 cactccagca ggctcgtaaa ttgatagcag aaggagccag tatgctcgat atcggcggag
    26041 aatcgactcg gccgggcagt agctatgttg agatagaaga ggaaatccag cgtgttgttc
    26101 cagtgatcaa agcgattcgc aaggaaagtg atgtccttat ttctatcgat acttggaaaa
    26161 gtcaggtggc agaggctgct ttggctgctg gtgccaatct agttaatgat atcactggtc
    26221 tcatgggcga tgaaaaaatg gcccatgtgg ttgctaaagc tggagcgaaa gtagtcatca
    26281 tgtttaatcc agtcatggct cgacctcaac atcctagttc gcttatcttc cctcattttg
    26341 gctttggtca aacctttaca gaaaaagagt tagctgactt tgaaacattg ccaatcgaag
    26401 acttgatggt ggctttcttt gaacgagcac tagcgagagc ggcagaagct ggtattacac
    26461 cagaaaatat cctgttggat ccaggaattg gctttggtct gaccaagaaa gaaaatctcc
    26521 tccttttacg ggacctggat aaactacatc agaagggcta tccaatcttt ctcggagtgt
    26581 cgcgcaagcg atttgtcatc aatatccttg aagaaagtgg gtttgaagtc aatcctgaga
    26641 cagagcttgg tttccgaaat cgggacacgg cttcggctca tgtaactagt atcgctgcga
    26701 gacagggtgt agaagtggtg cgcgtgcatg acgtagctag tcacaggatg gcagttgaaa
    26761 ttgcctctgc cattcgtctg gctgatgaag cggaaaattt agatttaaaa caatataaat
    26821 aagatgaaag aaattgaaaa caatcagtgg attgctaact accggacgga tcaaccgcat
    26881 tttggattgg aacgaatggt ggaactgtta gctttgcgtg gcaatcccca tctcaaactc
    26941 aaggtcctcc atatcggagg gactaacggc aagggctcga ctattgcttt tttgaaaaag
    27001 atgctagaaa agctagggct gagagttggc gtgtttagct cgccctatct cattcattac
    27061 acagaccaga ttagcatcaa tggggaatcg atctcagaag cgaggctaga agctctcatg
    27121 gcagactatc agtctttgct ggagggagaa gcggtcgcca atttacaggg cacaaccgag
    27181 tttgagatta tcacagccct ggcctatgac tactttgcct cagagcaagt agatgtggcc
    27241 atcatggaag ttggcatggg tggacttttg gatagtacca atgtctgtca gcccattttg
    27301 acaggaatta caactattgg cttggatcat gtggccctac ttggtgacac cttggaggcc
    27361 atagcagagc agaaggcagg tattatcaaa caagggatac ccttggtaac agggcgtatt
    27421 gctccagaag ccttgactgt gattgaccgc attgcggaag ggaaagatgc gccgagactt
    27481 gcctacggga cagattatca ggttcgtcat caagaaagtg tggtgacagg ggaagtcttt
    27541 gactatacaa gtgctgtcag acaaggtcgc ttccagacta gcctgcttgg tttgtaccaa
    27601 atagagaatg ctgggatggc catagcttta cttgatactt tttgtcaaga agatggtcga
    27661 gagctagcaa gcaatgactt tcttggtcaa gccttggaag aaacaagttg gccagggcgt
    27721 ttggaaatcg tgtcaagaga tcccttgatg attttggatg gagcccataa tccccatgct
    27781 atcaaggcct tgttggtaac cttgcaagaa cgttttgcgg attatcataa ggaaatcctc
    27841 ttcacttgta tcaaaaccaa agccttggag gatatgttgg acttgctggg agccatgcca
    27901 gataccgagc ttactctaac acattttgcg gatagtcggg cgacggatga aagcgtgctg
    27961 aaagaggcag ctaagtctag aaatctcagc taccaagatt ggcatgattt tctagagcag
    28021 aatttgacag ataaaaaaga agagaaacaa acagttagga ttgtcacagg ttccttgtat
    28081 ttcttgagcc aagtgagggc ctatctgatg gagaggaaga acgagaatgg atacacaaaa
    28141 gattgaagca gctgtaaaaa tgattatcga ggctgtagga gagaacgcta atcgcgaggg
    28201 cttgcaggaa acacctgctc gtgtagcccg tatgtatcaa gagatttttt caggtcttgg
    28261 tcaaacagca gaggaacatt tgtcaaaatc ctttgaaatt attgacgata atatggtggt
    28321 agaaaaggat atctttttcc ataccatgtg tgaacaccac ttcttgccat tttatggtag
    28381 agcgcacatt gcctacattc cagatggtcg tgtggcaggc ttgtctaagc tagcccgtac
    28441 ggttgaagtt tattcgaaaa aaccacaaat tcaagaacgt ttgaatatcg aagtggccga
    28501 tgccttgatg gactatctag gtgctaaagg agcctttgtt gtcattgagg cggaacatat
    28561 gtgtatgagt atgcgtggtg ttagaaaacc aggcactgca accttgacga cagtagctcg
    28621 tggtctattt gaaacagata aggacctccg cgaccaagct tatcgtttaa tggggctata
    28681 aaaagaatcc gcttcaagcg gatttttcta gaaaggaatc attatggatc aactgcagat
    28741 taaggatttg gaaatgtttg cctatcatgg tctttttcct agtgagaaag aattggggca
    28801 gaaatttgtc gtttcagcca tcctatccta tgatatgacc aaggcagcta cagacttgga
    28861 tttaacagcc tctgtccatt acggagaatt atgtcagcag tggacgactt ggtttcagga
    28921 aacgagtgaa gatttgattg aaacggtagc ctataaactg gtggaacgta cctttgagtt
    28981 ttatcctctt gtccaagaaa tgaagttgga actgaaaaaa ccttgggcac cggtgcattt
    29041 gtcactagat acttgctcgg taaccattca tcgccgcaag caacgagcct ttatcgccct
    29101 aggaagcaat atgggagata aacaagcaaa cttgaagcaa gccattgaca aactgcgagc
    29161 tcgtggcatc tatattctca aagagtccag tgtcttagcg acggagcctt ggggtggagt
    29221 ggagcaggat agctttgcca atcaagtggt tgaggtggaa acctggctac cagcacaaga
    29281 cttgttagaa accttgttag ccattgagtc agagctggga cgggtgagag aagtgcattg
    29341 gggacctcgt ttgattgatt tggacttgct ctttgtggag gaccagatcc tttatacaga
    29401 cgacctcata ttgcctcatc cttacatagc ggaacgcctt tttgtccttg agtccttaca
    29461 ggaaattgcg cctcatttta tccatccgac attaaaacaa ccgatccgca acttgtatga
    29521 tgctttgaaa aaatagaaaa actctagttt tcagttactt gcaactgaag gctagagttt
    29581 ttaaaatagg tcattttctt ctgggaggag gatagtttct ctaccgtaca tgtctaaaac
    29641 cagtactctt gggggataac gagggtcgaa aggatggtta aagtcaaaat caatggctgt
    29701 agggaggtgt tgacttgaaa agtggaaggt aatctttcct tggttattaa gcaattgaaa
    29761 ctcgagttct tcttccaatt caaagacatt ttttaagaaa tgatcgatga tataccaaaa
    29821 agagtcaatg atgtcatcgg gcaagctggt aacaatgcca aaactagcag accgcatgtg
    29881 ggtattggta aaagccatat ctctgtcccc tttcttttcc cttatcatac agcaaatagg
    29941 attaaaaatc aagaaaaggt gattttttga aaaggatttt aactacaggg aaaaataagg
    30001 aaaaaaattc ccaaaaatct accgaagtta ataggtaaat tcccaaatta acttgattat
    30061 ataactttca gtta
//
LOCUS       DAVBCA010000023        29768 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.023, whole genome shotgun sequence.
ACCESSION   DAVBCA010000023 DAVBCA010000000
VERSION     DAVBCA010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29768)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29768)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29768
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.023"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            132..494
                     /locus_tag="VQU19_000960"
     CDS             132..494
                     /locus_tag="VQU19_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480224.1"
                     /translation="MRLASESRQILDKLKDDVYNKLGYEVSYSSIVSQAVREYVPKKE
                     RIDWIKLKETAIPFSSLKQSNNWEYQTSLMLEKDVLILLSELQNFFLDVFQAKRIHRA
                     FCIRLCLRAQFLLSNNDS"
     gene            902..1201
                     /locus_tag="VQU19_000961"
     CDS             902..1201
                     /locus_tag="VQU19_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480225.1"
                     /translation="MNRNVLNFLRTESAERVSLYIDKANRLEGDVTLLAPSSQDLEDI
                     KNAMFSNPNLELKVARLDVMKKIAYASTRNHYLTGATIFGDISKGTYNCDPKSYV"
     gene            complement(1296..1733)
                     /locus_tag="VQU19_000962"
     CDS             complement(1296..1733)
                     /locus_tag="VQU19_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480226.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFITRLETSFEWLLLSGLIFFLA
                     QGLLLFLLVVRLKHQFAEIYPQINKKIRFYYLGVLTIDFLFFVLLAFISSQRFSSLMP
                     IITACHSTFYYMTADYLRENYPDFYDKHISNTYTILSISSFLV"
     gene            complement(1864..2498)
                     /locus_tag="VQU19_000963"
                     /pseudo
     CDS             complement(1864..2498)
                     /locus_tag="VQU19_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819460.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
     gene            complement(2709..3359)
                     /locus_tag="VQU19_000964"
     CDS             complement(2709..3359)
                     /locus_tag="VQU19_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HET2480227.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRMHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            3471..4313
                     /locus_tag="VQU19_000965"
     CDS             3471..4313
                     /locus_tag="VQU19_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HET2480228.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADARQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            4389..4826
                     /locus_tag="VQU19_000966"
     CDS             4389..4826
                     /locus_tag="VQU19_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HET2480229.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKKSKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTDIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            4894..5196
                     /locus_tag="VQU19_000967"
     CDS             4894..5196
                     /locus_tag="VQU19_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480230.1"
                     /translation="MYLVIGIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(5287..6360)
                     /locus_tag="VQU19_000968"
     CDS             complement(5287..6360)
                     /locus_tag="VQU19_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HET2480231.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPREPTMLTSKNRLQLLDKLAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHKIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSQQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILEAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYQAWKNR"
     gene            6516..7193
                     /locus_tag="VQU19_000969"
     CDS             6516..7193
                     /locus_tag="VQU19_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2480232.1"
                     /translation="MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            7186..8160
                     /locus_tag="VQU19_000970"
     CDS             7186..8160
                     /locus_tag="VQU19_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET2480233.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVEMQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLLLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQEICIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(8209..10152)
                     /gene="thrS"
                     /locus_tag="VQU19_000971"
     CDS             complement(8209..10152)
                     /gene="thrS"
                     /locus_tag="VQU19_000971"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HET2480234.1"
                     /translation="MINITFPDGAIREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHGDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(10210..10386)
                     /locus_tag="VQU19_000972"
                     /pseudo
     CDS             complement(10210..10386)
                     /locus_tag="VQU19_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166032.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
     gene            complement(10393..10533)
                     /locus_tag="VQU19_000973"
     CDS             complement(10393..10533)
                     /locus_tag="VQU19_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HET2480235.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDFKWTVEEDLLALSNDIGN
                     FQ"
     gene            complement(10964..11164)
                     /locus_tag="VQU19_000974"
     CDS             complement(10964..11164)
                     /locus_tag="VQU19_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480236.1"
                     /translation="MRRFYSHLPYYLVILFFYWPLYELFLLVVSDPLTLKGLYINNLL
                     FFTPMVILIVSLLYSYRFRFSL"
     gene            11403..11948
                     /locus_tag="VQU19_000975"
     CDS             11403..11948
                     /locus_tag="VQU19_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001852743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HET2480237.1"
                     /translation="MKLAVIAANGQAGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGSGS
                     LYIDETKTTRLLDTPDFPEEFKSLAKAQADELDLLRTKNNLNWAFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNEKRNKPD"
     gene            12174..12443
                     /gene="rpsO"
                     /locus_tag="VQU19_000976"
     CDS             12174..12443
                     /gene="rpsO"
                     /locus_tag="VQU19_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HET2480238.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            13259..13873
                     /locus_tag="VQU19_000977"
     CDS             13259..13873
                     /locus_tag="VQU19_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HET2480239.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(14165..14914)
                     /locus_tag="VQU19_000978"
     CDS             complement(14165..14914)
                     /locus_tag="VQU19_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HET2480240.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            15047..17383
                     /locus_tag="VQU19_000979"
     CDS             15047..17383
                     /locus_tag="VQU19_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HET2480241.1"
                     /translation="MDKNKIMGLTQREIKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAVASILTSYMA
                     HSEDKNPTAQAIRQRFQGQVVYPMLSNLPFSSDRKWGAMELEGLGIVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLNY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELIALAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRKSMLRALPSALMVVFSVLFVKIF
                     GTSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEISTLTEQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            17485..18162
                     /locus_tag="VQU19_000980"
     CDS             17485..18162
                     /locus_tag="VQU19_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HET2480242.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            18149..18946
                     /locus_tag="VQU19_000981"
     CDS             18149..18946
                     /locus_tag="VQU19_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HET2480243.1"
                     /translation="MLASEVIHAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            18963..20066
                     /locus_tag="VQU19_000982"
     CDS             18963..20066
                     /locus_tag="VQU19_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HET2480244.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQKIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLAILDQASANELFPGLQGFDRLLYASGGARVDGQLLVTRL
                     LEASHVKLVKEKVTLTPLASGYQIGEEEFEQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLVQDMEAYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDETLLQQME
                     EATLTHYLILAEATSKSERVGIRAYTSDFSPFFGQVPDLTGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPENYPIENYVKRVKSE"
     gene            20073..20264
                     /locus_tag="VQU19_000983"
     CDS             20073..20264
                     /locus_tag="VQU19_000983"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480245.1"
                     /translation="MKIKEQTRKLAAGYSKHCFEVVDRTDEVSSKHCFEVVDRTDEVS
                     NHTHGKATLTWFELDFRRV"
     gene            20367..21386
                     /gene="galE"
                     /locus_tag="VQU19_000984"
     CDS             20367..21386
                     /gene="galE"
                     /locus_tag="VQU19_000984"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HET2480246.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTATLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAIEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            21388..22341
                     /locus_tag="VQU19_000985"
     CDS             21388..22341
                     /locus_tag="VQU19_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET2480247.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTYYLDYPNVERQAGKTSWSFRKLFFYSIE
                     GIINFSDFPLIIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDDRLKKIEFI"
     gene            22493..23158
                     /locus_tag="VQU19_000986"
     CDS             22493..23158
                     /locus_tag="VQU19_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000949235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480248.1"
                     /translation="MLSKEDYTEEIGLIKKQNYVEAELYPIVADIIKPTLKDSLSKRY
                     VFGRQRRGLGQIYYGLSNFPDIVILDKTYENKSRKSIKIEEWKKLRGCVEVKNLNYSL
                     ITEEKIKSTISNSFEHITGEMEQLTGEMGQLIGDLLWYKKVIYTNGIEWRFLSLDDKE
                     EIDNTIVEVVNKRIETEEAGNSFDWWKNIKDLSFNYTDICLSKDCRQEWNEFVKRVKE
                     IEW"
     gene            23197..23298
                     /locus_tag="VQU19_000987"
                     /pseudo
     CDS             23197..23298
                     /locus_tag="VQU19_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677122.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group 2 glycosyl transferase"
     gene            complement(23349..23555)
                     /locus_tag="VQU19_000988"
     CDS             complement(23349..23555)
                     /locus_tag="VQU19_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HET2480249.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            23607..24083
                     /locus_tag="VQU19_000989"
     CDS             23607..24083
                     /locus_tag="VQU19_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HET2480250.1"
                     /translation="MAKEPWQEDIYDQEESRAERRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            24092..24763
                     /locus_tag="VQU19_000990"
     CDS             24092..24763
                     /locus_tag="VQU19_000990"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HET2480251.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDFETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            24894..25232
                     /locus_tag="VQU19_000991"
     CDS             24894..25232
                     /locus_tag="VQU19_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HET2480252.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLADGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            25235..25864
                     /locus_tag="VQU19_000992"
     CDS             25235..25864
                     /locus_tag="VQU19_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HET2480253.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITKHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            26104..27255
                     /locus_tag="VQU19_000993"
     CDS             26104..27255
                     /locus_tag="VQU19_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET2480254.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            27568..28317
                     /gene="truA"
                     /locus_tag="VQU19_000994"
     CDS             27568..28317
                     /gene="truA"
                     /locus_tag="VQU19_000994"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HET2480255.1"
                     /translation="MTRYKATISYDGYAFAGFQRQPHARSVQEEIEKTLTRLNKGQAI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFTVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            28307..29080
                     /locus_tag="VQU19_000995"
     CDS             28307..29080
                     /locus_tag="VQU19_000995"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HET2480256.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            29058..29519
                     /locus_tag="VQU19_000996"
     CDS             29058..29519
                     /locus_tag="VQU19_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET2480257.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
BASE COUNT         8722 a         5366 c         6695 g         8985 t
ORIGIN      
        1 taaattttta gattgtggaa tttttttcaa cttaattctt gatttttttt ctaaattgtt
       61 atatacttaa tttacgggat aacagaatcc cgtcagaaag gggtgataat atgggaaaag
      121 agaatgttag aatgcgttta gcgtctgaat ccagacagat attagataag cttaaagatg
      181 atgtttacaa taaattaggc tatgaagtaa gctattccag tattgttagt caagctgtta
      241 gagaatacgt tcctaaaaaa gaacgtatag attggataaa attaaaagag acagctatac
      301 ctttttcatc gttaaaacag agcaataatt gggagtacca gacatcactt atgttagaga
      361 aagatgtatt aatcttactg tctgaactac aaaatttttt cttagatgtc ttccaagcga
      421 aacgtataca tagggcattt tgtatacgtc tatgtttgag agcgcaattt ttattaagta
      481 ataatgattc ttaatactat caatattaat gcggagtgta atgctccgca aaaataaaac
      541 ctattacggg ataaaaacac tactttattt aggatggaaa taagaacgta ttttttacta
      601 atattgttta gaaaggagtt tctttatgac accagaagaa caaactgctt tggaatactt
      661 ttatgaggaa ctcgagagtt acggtgaaga tgagcaagga gaggtctttg atttgtatga
      721 taattaaatc atctccatag tttctgagaa taattgagaa actatactct aaatcatagg
      781 tttatgtaaa gctagatata cacaaaagga ggtacgaatg aagatgaaag ctagagcttc
      841 accgttgaat tgattttgtt tctagaaaaa atcaataatt agaaaaatac gaggtaaaaa
      901 aatgaataga aatgtactaa attttctgcg aacagaaagt gctgaaagag ttagtcttta
      961 tatagacaag gctaatagat tggagggcga tgtaactcta ctcgcaccta gttctcaaga
     1021 tttggaagat attaaaaatg ctatgttttc caatcctaat ctcgagctaa aagtagcgag
     1081 actggatgtg atgaagaaaa tagcatatgc ttctacaaga aatcattatt taacaggggc
     1141 tacgattttt ggggatattt cgaaaggaac atacaattgt gatcctaaaa gttatgtcta
     1201 atataaggga ggttaatccc tccccttgtt tttgaaaatc gaaaggaaaa gtataaaaat
     1261 gaaagttaat gaatatttct ggagaacgag ctgtcttata ctaaaaaaga agaaatcgat
     1321 aaaatagtat acgtgttaga gatgtgtttg tcgtaaaagt ctggatagtt ttctcttagg
     1381 tagtcagctg tcatataata aaaagtagaa tggcaagcag tgatgattgg cataagagat
     1441 gaaaaacgct gagaactaat gaaggctaag agaacaaaaa atagaaaatc aatggtgaga
     1501 acccctaaat agtagaagcg aatcttttta ttgatttgag gataaatctc agcgaattga
     1561 tgtttgagtc ggacgaccaa gagaaatagc aggagtcctt gagcaaggaa gaaaattaaa
     1621 ccagagagca agagccactc aaaagatgtc tcgagtctag tgataaaaaa tgcaaatagt
     1681 agcaaatcaa taactgcaat tgctataaaa tggattctat agagtttttt catgacaaga
     1741 cctccctctt ttatctaact tcattctact ctaaaagaat gggagttaca actaaaatga
     1801 taaaaatagc agaggggaga ttctcttaag ttggctagta ttctttattt gagtttcctt
     1861 ctattatcta acttcttcat cattccagac aaataaagct ccgattgcat tgaggatata
     1921 aaagatgtat ttaccgatat tggcgaagtt tccttgaata ccagcttttg tcagctgaac
     1981 gaaattgtaa atcaaccaaa agccccactg tccctcattg ccaatgcatt caaagcattg
     2041 gcaatgaggg acagtgcaaa ggcaatagtt gttacgtagg caaggagatt catcttgccc
     2101 ccatatccga tatagttggt cacaaaggca aagaggaagg cgatgatgga aatgatgatg
     2161 gccgccaatt ttacctgttt ttggctcatt tggttgggtc tgccttcttg cgaagctttc
     2221 catttcttta tagcaaaggt ataaatgagg aaggtgacgg gataggtaat gatggccgcc
     2281 ttatttccaa ggatataatc aatagcaccg gacaaaatgg tattaacaat accaaagtaa
     2341 ttttcccatt tgcttaattt ccccgtgaaa cgagtggaca acatggaaat cccaacgttg
     2401 gttacggaaa tcaatccaaa gggtacaaga gctgtccatg gtccccagtc tacaaattta
     2461 tcgaggcgtg agttgaggta accagatgca atcgcaatcc aacgaccaaa gcaaccccga
     2521 agaggtcaaa ctatttagat gtagcaaaaa tttttagtga ttttttcata ggttaaacta
     2581 cctttctttt tttcaaatat tctcccattt ttttttcaaa tattctacca ccaaatgaaa
     2641 gtaaaataaa atgatagaaa taaaaccctg aaaataaaac tttcagggtt ggtaggggac
     2701 ttgagaaatt agttgatttt ctcgacatag agttgttttg caatgtccat attcacttgt
     2761 aaatcctcgt cgttactgag gatagtgaag gtattgctga agccatcaaa ctgcttaact
     2821 tggagctggt caccgatgtg aagtgagtgc ttgtccagat aatggagaat gtcaaaacta
     2881 tcgtgcatcc gagtcaggcg gtaggcgcca gcttccttga tatcagctag tgggaggtta
     2941 ttgatttcaa cgaggagttc tcccttggca ggaatagttc ctccgtgggg gcaggtttta
     3001 gggaaaccta gcagtttatc tagtctttcc acgaacaggt cagagacagt gtgttccaag
     3061 acctcagctt cctcgtgaat ctggtcactt gtatagtcta aatgatgaac tagaaaaact
     3121 tcaatcaagc ggtgcttacg atagagctca gagaccagtt tgagaccgag gtcagtcagt
     3181 agatagccac attccttgtc ctttaggatg agattttcac ttttcattcg tttgatcatt
     3241 tcagttacgg cagggggaga gacttgcatg cgagccgcaa tttccttgtt ggtaatctta
     3301 tgcaggtcta tgccaatttc ataaatacat tttagatagt cttctttgtt tggggtcatt
     3361 cgtttcctct tgtctaatat ctttatctag tatatcaaaa aaagctagat ttctctagct
     3421 gtgacttttt atgttatact tattgcaaga gaaaaaacga ggagatggat atgacgaaaa
     3481 tagctcttct ttcagatatt catggaaata ccaccgcctt ggaggctgtt ttggcagatg
     3541 ctcggcagct aggagtggat gaatactggc ttttgggaga tattctcatg ccagggacag
     3601 ggcgtagaag gattttggac ttgttggatc aactaccgat tacggctaga gttttgggaa
     3661 actgggaaga cagtctttgg catggtgtcc gtaaggaatt ggatagtact cgccctagtc
     3721 aacgctatct cttgcgccag tgccagtatg ttttagagga aatttcccta gaagaaattg
     3781 aagtgctcca caatcaacct cttcaaattc atcgtcagtt tggggatttg acagtgggaa
     3841 ttagccatca tctgcctgat aagaactggg ggcgagagtt gattcatact ggcaaacaag
     3901 aggaatttga ccgcttggtg actcatcctc cctgtgatat tgctgtttat ggacacattc
     3961 accagcagtt gcttcgttac gggactggtg ggcaattgat tgtcaatccg ggttcgattg
     4021 gccaaccttt ctttttggac gctcagctac ggaaggactt gcgggcccag tatatgattt
     4081 tggagtttga tgacaagggc ctggtagata tggacttccg acgggtagat tacgatgtgg
     4141 cagctgaatt gcagctggct aaagacctga gacttcccta ttttgaggtt tactatgaaa
     4201 gtctggtcaa tgggatccac catactcatc atcaggaatt tttgagagaa ttggctcaga
     4261 aagagggttg cgatcgggag ttagacgact ggttgaaaag tggtaacgat tgacattaca
     4321 actaaaaagg gtataataat agaaaaagaa gagtagaggc agggtagcct cgtaaaaagg
     4381 agaagaggat gcaaattcca agtagattta ccattgcgac tcatatgctg ataatcattg
     4441 ccctcgaggg gaagaaaagc aaggtgacca gtgattttct ggctgctagt gtcggggtca
     4501 atcctgtcat tatcagaaag atcttgtccc agttgaagaa ggcagagctg atttcagtag
     4561 cgcgtggaac gggcggaaca gatattgtca aggaccttaa ggatattagt cttttagatg
     4621 tttatcaggc ggtcgaatgt cttggtaaga caggtcaact cttcagtttc catgacaatc
     4681 cgaatccaaa ttgccctgta ggagctcata ttcatgatgt tttggatcaa aaattggaga
     4741 gaattcagtt gactatggag gcagaacttg gtcaaaccag tctagaaaaa gtcgtggccg
     4801 atgcagagag tcagatgaag gattaagagg gataaatgcc ctcttttttc tttggataat
     4861 tatgataaaa tgtagctatt aaaggagtaa gaaatgtatc tcgttatagg aattgtatta
     4921 gcctttatag tgtcattttg gaaggataat agaagtttgt ggaatccagt attattttta
     4981 ttatccctca tttcaagtta tttttatcta tcctaccttt tttataaaaa tggatacgag
     5041 aatgttcagt tagcttttta tgtatttgcc tttgtcttac ttcctttttt gctttttcta
     5101 agtggcatct ttttaatcta taatggggtc attttgttga agcgagaggg acgttccaag
     5161 ccccattatc tctcaatgct ctttgatttt tattgactat tagattctat ttaaaaagac
     5221 ttagaatgca catgaaagta tgtattctag gtcttttgtt ttgtatacat ttaattttca
     5281 agagtattat ctatttttcc atgcctggta acgagtatca atcaataact gggtaaggcg
     5341 acccaaggtt tctctttctt ctggagtgag ggattgagct tggacaaaga gatgatgaat
     5401 gtattcaagc gcctttaagg aagccaagtc attgatagag ctaataccag cctcaagaat
     5461 agtgccaaag aagaggtcga agtagagctg aagttcttcg tcagggactg tggccaccca
     5521 ttctttaaag gttgtgtcta cttgctggct atcactgttg gtcttatcca gttggacgaa
     5581 gtgcttgtcc tcaatctgcc aactaaaggt atcgtgctgg gcgatgccac ccagggcagt
     5641 actctgaacg atgattttgt gagcaggaat ttccagcatc ataccgataa tggaaccttg
     5701 tggaatgaat atcttgcttc tatccattat cctttgataa cccgcagtct gtgtcaattc
     5761 ttgatggaga ccaggtgcat caaatgtata aactgctgtg atctgatttt gcaaactttg
     5821 ctcaatttgg ctagcagcat agatagcgag atttcctccc ttggaatgcc cagctagaat
     5881 aaccttttgc ttaggatgat gggcaaaaaa gttctttaaa tagcgaaggg cgtgcttttg
     5941 agcaggaatt tccttcatat aggtcaggtg gaaatcttcc ttccagccaa tgatactgtc
     6001 atctgtccca cgaaagacaa tcagataggt atcgaggctg acacgataag tcatagccgc
     6061 aaattgcttt tgcagttcag ggtcgatgtc gttgataaaa tgggagagtt tgcaattttt
     6121 gaagcgcttg tgttgagcca atttatctaa taattgaagg cgatttttgc tagtaagcat
     6181 ggtgggctct cttggaacct gaggtgctag atctaaaaga cgttgaggaa gtgtggagac
     6241 cagattatca aaggagaggt aggtgatttc tattaaggtt agaatgtcta actcattcaa
     6301 gggaaggtcg taataagaat catatgcgac atctttcaga tagtcaaaaa tattggccat
     6361 aagagctcct ttctttttat ttatcttagc aaatttccct caaattagct agtagcatag
     6421 cctgtttgca ctggctaaaa acaggctatt tcaaattcag tttcagacca tctagcatgg
     6481 aaaaatctgt tataataatg gaaaaggaga agcgcatgca caagatttta ttaatagaag
     6541 atgatcaggt cattcgtcaa cagattggga aaatgctctc tgaatgggga tttgaagtgg
     6601 tcctggtaga agactttatg gaagttttga gtctatttgt tcagtcggaa cctcatctgg
     6661 tcctcatgga tattggtttg cccttgttta atggttatca ctggtgtcag gaaatccgca
     6721 agatttccaa ggtacctatc atgtttcttt cttcgagaga ccaggctatg gatattgtca
     6781 tggcaatcaa tatgggggcg gatgactttg tgaccaagcc ttttgaccag caggttcttt
     6841 tagctaaggt tcagggcttg ttgcgtcgtt cctatgagtt tgggcgtgat gagagtttgc
     6901 tggaatatgc tggtgttatc ctcaatacca aatccatgga tttacattat caagggcaag
     6961 tcttgaattt gaccaagaat gaattccaga ttttacgcgt gttatttgag catgcaggca
     7021 acatcgtagc acgtgacgac ctgatgcggg aactttggaa cagtgacttt ttcattgatg
     7081 ataataccct ctctgtcaat gtggctcgtt tgcgtaaaaa gttggaggag cagggattgg
     7141 taggatttat cgagaccaag aaaggaatag ggtacggatt gaagcatgct tgattggaaa
     7201 caattttttc tagcctatct gcgctcccgt agtcgtcttt ttatctatct gctttctttg
     7261 gcatttcttg tcttactctt tcagttttta tttgccagtc taggaattta cttcctctac
     7321 tttttcttct tgtgttgctt tgtaaccatc ttatttttca cttgggacat attggtggaa
     7381 atgcaggtct atcgccagga acttctctat ggagagaggg aagccaagtc tcctttggaa
     7441 atagctttag cagaaaaatt agaagcgcgt gagatggaac tctatcagca gaggtcaaaa
     7501 gcagaaagaa aactgacgga tttgctggat tactatacct tgtgggtcca tcagataaag
     7561 acccccattg cagccagtca actcttagtt gcagaagtgg tcgaccgcca actgaagcag
     7621 cagctagaac aggaaatttt caaaatcgac tcttatacca acctagtttt acagtacctg
     7681 cgtttagaaa gtttccatga tgatttgctc ttaaagcagg ttcaaattga ggacttggtc
     7741 aaggaaataa ttcgtaaata tgctcttttc tttattcaaa aaggcttaaa tgtcaatcta
     7801 catgaccttg ataaagaaat cgtgacggat aaaaagtggc tgctagtggt tattgagcaa
     7861 atcatctcaa acagtctcaa gtacaccaag gaaggtggtc tggagattta tatggatgac
     7921 caagagattt gtatcaaaga tacgggaatc gggataaaaa acagtgatgt cctccgagta
     7981 tttgaacgtg gcttttcagg atacaatggc cgtttgaccc agcagtcctc tggacttggc
     8041 ctttatctat ctaagaaaat ttctgaagaa ctggggcacc agattcgtat cgagtctgag
     8101 gtcggaaaag gaacgacagt gcggattcag tttgctcaag tgaacttagt ccttgagtaa
     8161 aaatagatga gaaaaagcct ccagattgga ggcttttatg ctagactctt atttctcaac
     8221 gcgtgatttg ttggcgatat cagctaggat agcttgaaca aaattatcaa ctgagacagt
     8281 ttgtgtttct ttttggccgt agcgacgaac gttgactgtt tcgtcttcca tttctttgtc
     8341 tccaacaatt aattggtaag gaatcttgct ggtttgtgaa gcacggatct tgaactgcat
     8401 tttttcattg cgctcatcta cgtctgcacg gacaccgcgg tcacggagtt tcttggctac
     8461 ttcccaagcg tagtccacgt gtttttcgtt agatactggg atgagggtta cttggtgtgg
     8521 tgccagccat gttgggaagg cccccttgta gttctcaatc aagatagctg tgaagcgttc
     8581 catagttgag ataaccccac ggtggatcat gactggacgg tgatcttcgc catcagctcc
     8641 gatgtatttg aggtcgaagc gttctggcaa caagaaatca agttggatag tagaaagggt
     8701 ttcttctttt ccaagggcag ttttaatctg gatatccaat tttggtccgt agaaggctgc
     8761 ttcaccttcg gcttcaaagt agtccacgcc catttcatca agagctgcac gaagcatggt
     8821 ttgggcattt tcccacatct catcgttatc aaagtactta tgagtatctt gagggtcacg
     8881 aagagagagg cggaagcggt agtcagtcaa gttgaagtct tcataaacat cgataatcaa
     8941 ctgaagggca cgttggaatt cttcttggat ttgttctgga gtaacgaata ggtgaccgtc
     9001 gttgagtgac atttcacgta cacgttgaag gccagtgagg gcaccagatt tttcgtaacg
     9061 gtgcatcata ccgatttcag cgatacggat tggcaattca cggtaagagt gaacatggtg
     9121 tttgaaaact tggatgtggt gcggacagtt cattggacga aggacaaatt cttccccgtc
     9181 acccatgtcc atggttggga acatgtcttc ttggtaatga tcccagtgac cagaagtctt
     9241 gtaaagctca acagaagcaa gtggtggagt gtagacgtgt tggtagccag aagccaactc
     9301 tttgtttacg atgtagcgtt ccaattcacg acggatagtc gcaccatttg gcaaccagaa
     9361 tggcaaacct tgtcccactt cttgtgaaat cataaagagg tcaagctctt taccaagttt
     9421 acggtggtca cgttccttag cttcttcacg catttgaagg tagtttttca agtctttctt
     9481 gtcaaaccaa gctgtaccgt agatacgttg catcatagcg ttgtcgctgt ttccacgcca
     9541 gtacgcacca gctacatgga gaaggtggaa gatttggata cgacctgttg atggaacgtg
     9601 aggtccacgg cagaggtcta catattcacc ctgacgatag atagtcaaac cgccttcgtc
     9661 ttctgagtgt tcttcaatca attccaactt gtaagggtca tttttgaaga tttcacgtgc
     9721 ctcgtcttta gtcacttctt cacgaataga tgggaagttt tctttgacga ttttttgcat
     9781 ttcttcttcg atacgaggaa ggtcttcgtt agagatttga ccagctgtgt tgtcagtatc
     9841 gtagtagaaa ccatcttcga tggctggacc aactcccaag tgaatgtctg ggaaaagacg
     9901 acgagctgct tgggcgaaca agtgagctgc tgagtgacgc aagattggaa gggcatctcc
     9961 gtgatcaggt gtcacaattt cgatgcttcc atcttcagtg atagcgcgag tagtgtcgat
    10021 gagtttgccg ttgaatttac cagccaaggc ttttttagct agggaattgc tgatagattg
    10081 ggcaatttca aaagttgtta cgccagattc gaattcacga atagcgccat ctgggaaagt
    10141 aatgttaatc atgatgttct ccttttttat tatttcatag tttctaagca ttgatttttt
    10201 atcagcagac tacttccaag ttctaacgtt caattgcttt tctttatcag agaggaagtt
    10261 ttccatttcc gtcagaatat ctatatccaa acgttgagaa agttctaata gtcaccagat
    10321 attttctgaa agtttttgtt ccagtgtgta gggtgtttca tcatagtagc gtccttgctt
    10381 tgtcatcacc agtcattgga aatttccaat atcattagat aaagccaaga ggtcttcttc
    10441 taccgtccac ttgaaatcat gatgcttaac ttccagttcg tgataagctt gtcggattgc
    10501 ccaactgcgc tccactaatt cttgcaactc cataattagt atcctaataa aaaaatgcga
    10561 catcctcgaa aggacgtcgc aacgtggttc caccttcatt tatgtacctc aaaagagagg
    10621 gacacctctg atcggctcta acgtggccac cgttttatgt tttcataaaa aactcaagag
    10681 tagtatcagt ttagacttcc tatgcgtttc cagcaaccac gcactctcta gtagaaaggg
    10741 actaagtgac ttgtctctat ggattattat agcatgattg tgagattttt caaggatttt
    10801 gtgaaagttt tttgtttttc attttttgta gaatatgctt gatgctaata ccagaatcca
    10861 tgcccaccag agcaactgtt tcatagatta gcaagtaaat tagtataaac acaccaaagg
    10921 ttatgatagt aaagtaaaag agcagtccgt taccaactaa ccatcaaagt gagaaacgga
    10981 aacggtagct atagagtaac gatacaatca agattaccat aggtgtaaag aagagaagat
    11041 tgtttatata gagtcccttg agtgtaaggg ggtcagaaac aactagcaag aacaactcat
    11101 aaagtggcca ataaaagaat aatatgacca gatagtaggg gagatgggaa tagaatctac
    11161 gcatgataat cacctcgttt taaaaaaaca gacaacttag atctcttgct atgattatta
    11221 tagtatgttt aaaacaagaa agtaaatttg ttgacaaaga agatttttct tttcactaga
    11281 atcatggtta gttttcttgg tagaaatatt ttgataataa ttaagcaaga ctattgacat
    11341 tgattattaa gagtgtcaca attgttgtaa ctaaaataat tacaacaaga ggggtataaa
    11401 aaatgaaact agcagttatt gcagcaaatg gacaagcggg gaaggcaatt gttgaagaag
    11461 cagtcaaacg aggacatgaa gtaacggcta ttgttcgttc tgaaaacaaa agtcaagctg
    11521 agtctattat taaaaaagat ttatttgagt tgacaaaaga tgatcttact ggatttgatg
    11581 ctgttatttc agcgtttggt gcttatacac cagatacgct accgctccac agcaaatcaa
    11641 tcgaactatt taatcagctt cttgctggaa cacagacacg ttttctagtt gtagggggat
    11701 caggaagcct ttatatagat gaaacaaaaa cgacacgact tttagatacg cctgattttc
    11761 ctgaagaatt taagtcacta gcaaaagctc aagcggatga attggatctt cttcgtacaa
    11821 aaaataatct caactgggct tttgtcagtc ctgctgtaga ttttattccc gatggtgaaa
    11881 aaacaggaaa ctacattcta gcaggagaaa tttttactac taatgaaaaa aggaataagc
    11941 cagattagtt atgcagatta tgctattgga ttggtagatg aacttgaaaa aggtcatcat
    12001 ataaaagaac gtatctcttt acttgaaaaa taataactat gagagtatta atgtttgaca
    12061 gaaaatttaa atcttggtag aatagggatt gtcgtaaaga caaataactt cttcttggtt
    12121 acaggcatgc caacctgtca ctcggatgaa gccaaataaa aaggagaaac atcatggcaa
    12181 tctcaaaaga gaaaaaaaat gaaatcatcg cacaatatgc acgtcacgaa ggtgatacag
    12241 gttcagtaga ggttcaagtt gctgtcctta cttgggaaat caaccacctt aatgaacaca
    12301 tcaaacaaca caaaaaagac cacgctactt accgtggatt gatgaaaaaa atcggtcgcc
    12361 gtcgtaactt gcttgcatac ttgcgtaaaa acgacgttaa ccgttaccgt gagttgatca
    12421 actctctagg acttcgtcgc taattcaaga tacaaaggct gtcaaaagca caaagtaaaa
    12481 ataggaaaat ttacgaagaa acttcagttt ctaggagatt ttatcttttt tgccaagtgc
    12541 ttaggccgtg ttcaattgag catatcttga taatgaagct actctaaatt gggtagcttt
    12601 tttgtgttgt caccttacct cgatatactc aagtataatc tttggttacg gttcctagca
    12661 ctgtaaggta aaataaacca gcttttctcc cttcggggag attttttttg tttcactgaa
    12721 agtttcgtac gatcttcgcc tcgtcgccta gtctataaac gatttatcta gcaagaatca
    12781 tgatgctaag ggcgtcaaaa atccgtatga aaatagggaa atgacacagt gttcgatgag
    12841 cacaaggagt ttcatctttt tcactaggat tttagcccgg actcaaatca gctctctgac
    12901 ttcagagggc ttttttattg aggttttatc ggtaacaatt ttggagacta caaaaacctc
    12961 aaacggtatc agctaattac accataaagg tgcgcagtta ctcggctttt caagccgagt
    13021 agttgtatgc aagcccccta gaagagccca ctctttacaa agtaaagtat agtatgttat
    13081 actttacatg gaagtagtca ctgaattcca gttagaaatt actttgtaac tacgttttga
    13141 ggaggagtaa aatgctttcc tacgttcgat attacccact agcgatagct aaattaatgt
    13201 gtctgtgctc tcctaaaatc tgctgattta ttactgacta atacaggagt ttttttttat
    13261 gggacagaca atcatatctg ctattggtgt ttatatttcc accagtatcg attatttaat
    13321 tattttaatt attttatttg cacagctatc acagaataaa cagaaatggc atatttatgc
    13381 ggggcaatat ctaggcacag gcttacttgt aggggcgagt ttagttgctg cttatgtcgt
    13441 taatttcgtg cctgaagaat ggatggttgg attgcttggt ttaatcccta tctatttagg
    13501 gattcgcttt gcaattgttg gagaagatgc ggaagaagaa gaggaagaaa ttattgaaag
    13561 attagaacaa agcaaggcaa atcaactgtt ttggacagtt acattgctga caattgcgtc
    13621 tggcggagat aatttaggta tctatatacc ttattttgct tcgttagatt ggtcacagac
    13681 cctcgtggcc ttgcttgtgt ttgtaatcgg cataattatc ttttgcgaga ttagtcgggt
    13741 gttatcttct attccgttaa tattcgagac aattgaaaaa tacgagcgaa tcattgtgcc
    13801 cttagtattc attctacttg gactatacat catgtatgaa aatggcacga tagagacttt
    13861 tctgatcgtg tagatttttt tgtttcacta ggattttagt ccgagctcaa atcagctctc
    13921 tgattttcag agggcttttt cattgagtat aaatggacaa tcttaaagtt actctattgt
    13981 agagtggctt ttgatttgat taggagattc ttataaatat agtaaaatga aataagaata
    14041 ggacaaatcg atcaggacag tcaaatcgat ttctaaaaat gttttagaag tagaggtgta
    14101 ctattctagt ttcaatttga tatataaatg aaaaccttag ctgtttggcc aaggttcatt
    14161 tcttctatgc aagttcttct cttttcttat ctgggttcca gatgaagctt gcgataaagc
    14221 taaagatgat ggttaggata gcgagaataa tagcaaggat gagggcaggg atgcggataa
    14281 accaccagag tggatttggt tttttatcat tgtgccattg tttcgtttct tcgtccagac
    14341 gttggaattc tgtttgaata cgattggcga ctgtttcaat gccttcatca ttcattttct
    14401 tgatatctga gatatcgatt ggatttccaa agttcatatc gacacgttca cggctaatca
    14461 agcccttcaa agtcatggga ccggtgtagg taaccggcat gatacggacc ttggccattt
    14521 tggcaatcag tgctgcgccc cccttgacat cgtttgagtg gcggctacca cttggaaaca
    14581 tgatgagaga gcggtcactt tttttgagaa cgttgatagg atatttgatg gctgaggcgc
    14641 tgggattttc acggtcgatg ggaaaggcgc cacacatacg aatccaccaa ccaaagatac
    14701 ggttggtaaa gagttctttt tttgccataa agatgaactg ttttggcttg gtcgcaaagg
    14761 ccatataaac aggatcccac caggtacggt gaggcgcaac taaaatataa ttttcatctt
    14821 gattaggaat tttatcagta ttatgatagt gagcattgcc attgatggac cataagagca
    14881 atacaactaa tccacgcaaa taagtataaa acatgcgatc tccttcgatt gttttcttgt
    14941 tattattata ccttatcaaa ggagggctgg caaacttttc ccttgactag atgcatattt
    15001 gggatgaaat tagaattctg ttaaaaaaaa tgatataata gaatttatgg ataaaaataa
    15061 gattatggga ttaacccaaa gagaaatcaa ggaaagacag gctgagggtt tggtcaatga
    15121 ctttaccgca tcagccagta ccagcacttg gcaaatcgtt aaacgaaatg tctttaccct
    15181 ttttaacgct ttgaactttg ccattgcttt ggcccttgcc tttgtgcagg cttggagcaa
    15241 tctggtcttc tttgctgtta tctgctttaa cgctttttct gggattgtga ccgagctacg
    15301 agccaaacac atggtggaca agctcaatct catgaccaag gaaaaggtca aaaccatccg
    15361 tgatggtcag gaagttgctc ttaatcctga agaattagtg ctaggagatg tcattcgttt
    15421 gtctgcagga gagcagattc ctagtgatgc cttggttttg gaaggctttg cggaagtcaa
    15481 tgaagccatg ttaacgggag aaagtgattt ggtgcaaaag gaagttgacg gcttactttt
    15541 gtcaggaagt ttcctagcca gtgggtcagt tttatctcaa gttcaccatg tcggtgcaga
    15601 caactatgct gccaaactca tgcttgaggc taagaccgtt aaacccatca actcccgtat
    15661 catgaaatcg ctggacaagt tggctggttt tactgggaag attatcattc cctttggtct
    15721 ggctctcttg ctggaagcct tgcttttaaa aggcctgcct ctcaagtcat ccgttgtaaa
    15781 ctcgtcgaca gctcttttgg gaatgttgcc taagggaatt gcccttttga ccattacttc
    15841 gctcttgact gcagtgatta agttgggctt gaaaaaggtc ttggtgcagg agatgtactc
    15901 tgttgagacc ttggcgcgcg tggatatgct ctgtctggac aagacgggta ccatcaccca
    15961 aggaaagatg caggtggagg ctgttcttcc actgacggaa acttatggtg aagaggctgt
    16021 tgccagcatc ctgaccagct atatggccca tagtgaggat aaaaatccaa cagctcaagc
    16081 cattcgccag agattccaag gtcaagtagt ctatcctatg ctctctaatc ttcccttctc
    16141 cagcgaccgc aagtggggag ccatggagtt agaaggtttg ggaatagttt tcttaggggc
    16201 acctgagatg ttgctggatt ctgaggtccc agaagccaga gaggccttgg agagaggatc
    16261 acgtgtcttg gtcttagctc tcagtcagga gaaattagac catcacaaac cacagaaacc
    16321 atctgatatt caggctctag ccttgctgga aatcttggat cctattcgag agggagcggc
    16381 agagacgctg aactatctcc gttctcagga agtggggctc aagattatct ctggtgacaa
    16441 tccagttacg gtatccagca ttgcccagaa ggctggtttt gcggactatc acagctatgt
    16501 cgattgttca aaaatcacgg atgaggaatt gattgctctg gcggaggaga cagcgatttt
    16561 cggacgtgtt tcccctcatc aaaagaaact cattatccaa acgctgaaaa aagcgggtca
    16621 tacaacagct atgactgggg atggagttaa tgatatcctg gctcttcgtg aggcggattg
    16681 ttctatcgta atggcggagg gagacccggc aacccgtcag attgccaacc tggttctctt
    16741 gaactcagac tttaatgatg ttcctgagat tctttttgaa ggtcgtcgtg tggtcaataa
    16801 cattgcccac atcgctccga ttttcttgat aaagaccatc tattccttcc tgttagcagt
    16861 catctgtatt gccagtgctt tactaggtcg gtcagagtgg attttgattt tccccttcat
    16921 tccgatccag attaccatga ttgaccagtt tgtggaaggt ttcccaccat tcgttctgac
    16981 ttttgagcga aatatcaaac ctgttgagcc aaatttcctc agaaaatcca tgcttcgtgc
    17041 cctaccaagt gccctcatgg tcgtgtttag cgttcttttt gtgaaaatct ttggaacgag
    17101 tcaaggttgg tctgagttag aaatctcaac tctcctctat tatctcttgg ggtcaattgg
    17161 tttcttatcc gtatttagag cctgcatgcc attcactcta tggcgagtcc tcttgattgt
    17221 ctggtcagta ggaggcttcc tagccacagc tctcttccca agaatccaaa aactgcttga
    17281 aatttcaacc ttgacagaac aaacgttgcc tgtttatggt gtcatgatgt tggtctttac
    17341 agtgattttc atcctgacta gtcgctatca agctagaaaa taaagaaaga ctgcaatctg
    17401 tggattgcag tttttttagg tacaagattg ccagccgaaa tgtggtataa taagaggtaa
    17461 tagagttttg gaaagtgaga gaagatgatt tcaaagagat tagaattggt agcttccttt
    17521 gtgtcacagg gggctatttt actagatgtg ggaagtgacc atgcttatct gcctatcgag
    17581 ttggttgaga gaggccaaat caaaagcgct attgcaggtg aggtggtgga aggtccctat
    17641 cagtctgcgg ttaaaaatgt tgaggctcac ggcctaaagg agaaaatcca agtccgttta
    17701 gccaatggct tggcagcttt tgaagagact gaccaagtgt ctgtcattac cattgctggc
    17761 atgggtggtc gtttgattgc taggatttta gaagaaggtt tggggaagtt agctaatgta
    17821 gagcgtttga tcctccagcc caataatcgt gaagacgact tgcgtatctg gctacaggat
    17881 catggattcc agattgtagc agaaagcatc ttagaagaag ctggaaagtt ttatgagatt
    17941 ttggtggtgg aagcaggaca aatgaagcta tcagccagtg atgttcgctt tggtcccttc
    18001 ttgtccaaag aagtcagtcc agtatttgtc caaaaatggc aaaaagaagc tgagaagcta
    18061 gagttcgctc tcggacaaat cccagaaaaa aatctggaag aacgtcaagt tctagtagat
    18121 aagattcaag ctatcaagga ggtgctccat gttagcaagt gaagtgattc atgcttatga
    18181 agccttttgc cctcaggaat tttctatgga gggagacagc cgtggtctgc aaattggcac
    18241 tttagacaag ggtatccaaa gggtcatggt tgccctcgat attcgtgaag agacagtggc
    18301 agaggccatt gaaaagggtg tggacttgat tatcgtcaag cacgcgccta tctttcgtcc
    18361 tatcaaggac ttgcttgcca gccgtccgca aaatcagatt tacatcgacc tgattaagca
    18421 tgacatcgca gtttatgtca gccataccaa tattgatatc gttgaaaatg ggctcaatga
    18481 ctggttttgt cagatgctag gaatcgagga gacgacttat ctgcaggaaa caggtccaga
    18541 acgtggaatt ggacgtattg ggaatattca gcctcagaca ttttgggaat tggcccaaca
    18601 ggtcaagcaa gtctttgacc tagatagcct tcgaatggtg cattatcaag agaatgattt
    18661 gcagaagcct atttcaagag tagcaatttg tggtggaagc gggcagtctt tctataagga
    18721 tgctttggca aagggggcag atgtctatat cactggtgat atctactacc atactgctca
    18781 ggatatgctg tctgatggct tgttagcatt ggatccaggt cactatatcg aagtgctttt
    18841 tgtggaaaaa atcgcagcac tccttactca atggaaagag aaaaaaggct gggaactaga
    18901 gattttacct agtcaagcat cgaccaatcc tttccgtcat atctagttag aaagtgaaga
    18961 caatgaaaaa agttgccatt attggagcag gaattgtggg agcaacagct gcctactacc
    19021 tctcgagaga aagtgaccta gaggtgaccg tttttgacca tgagcaaggt caagccacca
    19081 aggccgcagc aggaattatc agtccttggt tttccaaacg ccgtaataaa gcctggtaca
    19141 agatggcgcg cttgggggct gatttttatg tggatttatt agctgattta gagaaatcag
    19201 gacaaaaaat cgacttttac cagcgttcgg gagtctttct cttgaaaaag gatgaatcca
    19261 agttggaaga actttatcaa ctggccctcc agcgcagaga agaatctccc ttgatagggc
    19321 aattagccat tctggaccaa gcctcagcta atgaattatt ccctggtttg cagggatttg
    19381 accgcctgct ctatgcttct ggtggagcga gagtagatgg ccaactcttg gtaactcgtc
    19441 tgctagaagc cagtcatgtc aagctggtca aagaaaaagt gactctgaca ccgttagcat
    19501 caggctacca gattggtgaa gaggagtttg agcaggttat tttggcgacg ggagcttggt
    19561 tgggggacat gttagaaccc ttgggttatg aagtagatgt tcgtcctcaa aaaggacaac
    19621 tacgagatta tcagctggtc caagacatgg aagcttaccc tgttgtcatg ccagaagggg
    19681 agtgggattt gattcctttt gcaggtggga aattgtcctt aggcgctacc cacgaaaatg
    19741 acatgggatt tgatttgacg gtagatgaaa ccttgctcca acaaatggag gaggccacct
    19801 tgactcacta tctgattttg gctgaagcta cttcaaaatc tgagcgtgtt ggaatccgtg
    19861 cctacaccag tgatttctct cctttctttg ggcaggtgcc tgacttaact ggtgtctatg
    19921 cagccagtgg actaggttca tcaggcctca caactggtcc tattattggt taccatttag
    19981 ctcaactgat ccaagacaag gagttgacct tggaccctga aaactaccca attgaaaact
    20041 atgtcaaacg agtaaaaagc gaataatact caatgaaaat caaagaacaa actaggaaac
    20101 tagccgcggg ttactcaaag cactgctttg aggttgtgga tagaactgac gaagtcagct
    20161 caaaacactg ttttgaggtt gtagatagaa ctgacgaagt cagtaaccat acccatggca
    20221 aggcgacgtt gacgtggttt gaattggatt ttcgaagagt ataagcattt tactgaaatt
    20281 ttatcaggta gtttaggatg gcaaatgaca ttccctgtca aaaatggtaa aataagaaaa
    20341 aataatctga gaatcgagga aaaaagatgc aagaaaagat tttggtaact ggtggtgccg
    20401 gttttattgg aacccacact gttattgaat tgatccaagc aggccatcaa gttgttgtgg
    20461 tggataatct tgtcaatagc aatcgtaaga gtttagaagt tgttgaaaga atcacaggag
    20521 ttgagattcc tttctatgag gcagatattc gtgacacagc taccctcaga gatattttca
    20581 agcaggaaga accgactggt gtcattcact ttgctggttt gaaggctgtt ggcgaatcaa
    20641 cacgtatccc tcttgcctac tatgacaaca atatcgctgg aactgtcagc cttttgaaag
    20701 ccatagaaga aaacaactgt aaaaacatca tcttcagttc ttctgcgaca gtttacgggg
    20761 atccgcacac agtgcccatc ttggaagatt tcccactttc agtgaccaac ccatacggtc
    20821 gtactaagct catgctagag gaaattttga ctgatattta caaagcagac tcagaatgga
    20881 atgttgtctt gcttcgttac tttaacccaa tcggagccca tgagagtggt gatttgggag
    20941 aaaatccaaa cggtattcca aacaatctct tgccatatgt gactcaagta gccgttggaa
    21001 aattagagca agtgcaagtg tttggagacg attacgatac ggaagatgga acaggtgttc
    21061 gtgactatat ccacgttgtc gatttggcta agggtcacgt tgcagctttg aaaaaaatcc
    21121 aaaaaggttc aggactaaac gtttataacc ttggaactgg taaaggttac tcagttcttg
    21181 aaattatcca aaacatggaa aaagcggtgg gacgtcctat tccttaccgt atcgtagaac
    21241 gtcgcccagg tgatatcgct gcctgctact cagacccagc aaaagctaaa gcagaactcg
    21301 gttgggaagc agaactcgac atcacccaaa tgtgtgaaga cgcatggcgt tggcaaagca
    21361 agcatccaaa tggatttgaa gactaagatg atgatttcaa tcatcgtccc ttgtttaaac
    21421 gaagaggaag tacttcctct tttttatcag gctctggaag ctttacttcc agatttggaa
    21481 acagaaatcg agtatgtctt tgtcgatgat ggatcaagtg atgggacctt ggaactctta
    21541 aaggcctatc gggagcaaaa tccggcagtc cattatattt ctttctctcg aaattttggc
    21601 aaagaagcag ccctttatgc aggcttgcaa tatgcgacag gagatttggt ggtggtgatg
    21661 gatgcagacc tccaagatcc tcctagtatg ttgtttgaga tgaaaaatgt actagacaaa
    21721 aatgtagact tggactgcgt tgggacacgg agaactagtc gggagggaga acccttcttt
    21781 cgcagtttct gtgctgttct cttttatcgc ctcatgcaaa aaatcagccc agtggctctg
    21841 ccgtcgggtg tccgtgattt tcgtatgatg agaaggtctg tagtcgatgc cattttaagc
    21901 ttgaccgagt ccaatcgttt ttcaaagggg ctcttcgcct gggtgggttt caaaacctac
    21961 tatttggact atccaaatgt cgaaaggcag gctggcaaga ccagttggag ttttaggaaa
    22021 ctctttttct actccattga agggattatt aatttttcag attttccctt gattatagcc
    22081 tttgtagctg gtctcctatc ttgttttctt tctctgctga tgaccttttt tgttgtggtt
    22141 cggaccctca ttttgggcaa tccgacatct ggttggacct ctctgatggc tgttattctc
    22201 tttcttggag gcattcaact cttgaccatt gggattctcg gcaagtatat cagtaagatt
    22261 tatttagaga ctaaaaaaag accactttat cttatcaaag aaaaaagtga tgataggcta
    22321 aaaaagatag aatttatctg acatagtcac tttttgttat ttgtaattct tttagttcgg
    22381 agtttgggtg atttttaaaa gaattaggga tttgaaatga tttaaaaaat ctatgtagac
    22441 taaatttaaa ttgtagtgac ttaataaata aaaaatttag gagtattatg ttatgctaag
    22501 taaagaggat tatactgaag aaatcgggct aataaagaaa caaaattatg tagaggctga
    22561 attgtatcct atagttgctg atataattaa gccaacttta aaagatagtt tatcaaaaag
    22621 atatgtcttc ggaagacaaa gaaggggttt gggacaaatt tattatggtc taagtaattt
    22681 tcctgatata gttattttag ataagactta tgaaaacaaa tctaggaaaa gtataaaaat
    22741 tgaagaatgg aagaaacttc gaggatgcgt ggaagttaag aatttaaatt atagtttaat
    22801 tacagaggaa aaaatcaaat caaccatatc gaacagtttt gaacatataa ctggagagat
    22861 ggaacaacta actggagaga tgggacaact tattggagac cttttatggt ataaaaaagt
    22921 aatttataca aatggaattg aatggagatt tctaagttta gatgacaagg aagagataga
    22981 taatacaatt gttgaagtag ttaacaaaag aatagaaaca gaagaagcgg gaaattcttt
    23041 tgattggtgg aagaatatta aagatttatc gttcaattat acggatatat gcctatctaa
    23101 agattgtaga caagagtgga atgaatttgt aaaaagggta aaggaaatag aatggtagaa
    23161 gtctattctc attgagaaat ttagatttta agttacagta agatttattt agagactaaa
    23221 aaaagaccac tttatcttat caaagaaaaa agtgaccttc ctgattttac agaaaaaaat
    23281 aaagtgaaaa gactataatt ttacatggaa atgtgctaaa ctagagggag tggattatcg
    23341 ccattgattt aggcttcctg gtttccaatc agggcgcgag ttgggcaatt tttaacagcc
    23401 tctaagacat cctgactagg agaaatttct ttttccagtt ggtcagggtc atcgtaaaaa
    23461 cgcacgattc cattatcgtg gtaatcaaat aaatcagaat aagtttggca aagcccacag
    23521 gcgatacatc gttcaggtat aagtgtgatt ttcatgttca tatttatatt gtaataagaa
    23581 aagtaaaaaa aaacaaggag taaggtatgg caaaagaacc gtggcaagaa gatatctatg
    23641 atcaagaaga atcaagagca gagcgtcggc atcgaaacca cggaggggct gataggatgg
    23701 ctaatcgtat tttgacgatc ctagctagta ttttctttgt aattgtggtg gtgatggtca
    23761 tcgttctcat ctatctatca tcggggggaa gtaatcgcac agcagcctta aaagactttc
    23821 atgattctga tgcaagtgta gtacaaatct catcttcaag cagttctcag cctgagcaga
    23881 gttcagagcc agaatctact tctagtagtt cagaagaagc tgctaatcct gaaggaacga
    23941 ttaaagttct cgcaggagaa ggggaagcag ctattgccgc tcgtgcagga atctccattg
    24001 ctcagttaga ggccttgaat cctgggcaca tggctacagg atcttggttt gctaatccag
    24061 gtgatgttat aaaaataaaa taggagccga tatgaaaaca attcaaattg ctattgatgg
    24121 tcctgcttcc agcggtaaga gtacggtcgc aaagattatt gctaaggatt ttggattcac
    24181 ctaccttgat acaggagcta tgtatcgtgc agcgacctat atggctctta agaaccaatt
    24241 aggagttgaa gaagtcgaag cccttctagc cttgttggac cagcatccaa tcagctttgg
    24301 acgttcagaa actggagacc agcttgtttt tgtaggagat gtggatatta cccatcctat
    24361 ccgtgaaaat gaagtgacca atcatgtttc tgctattgca gcaattcctg aagtgcgtga
    24421 gaaactggtt tctctccaac aagaaattgc ccagcaaggc gggattgtca tggatggtcg
    24481 cgatattgga actgttgtat tgccacaagc agaattgaaa attttcctag tagcttctgt
    24541 tgatgagaga gcagagcgtc gttacaagga aaatattgcc aagggaattg aaacagactt
    24601 tgaaacccta aaaaaggaaa ttgctgcgcg tgactacaag gatagtcatc gtgagacttc
    24661 tcctctcaaa caagcagagg atgctgtcta ccttgataca actggtttga acattcaaga
    24721 agtagttgaa aaaatcaaag cagaagctga aaaaagaatg taaatgtaga aaagccgata
    24781 gattgatatc ggtttttttc taaatttgtc aaaatgctga ttttagggta taatagttgc
    24841 tgttcgagaa attttgattt tcaaagaata gtgaatgatg ataaggagaa accatgaaca
    24901 atttaccaaa ttgtccaaaa tgtaactcag agtatgtcta cgaagacggt gccctactgg
    24961 tttgcccaga gtgtgctcat gagtggaatc ctgctgaagt tgcagaagta gaagaaggtc
    25021 ttgtcgctat cgatgccaac ggaaataaat tggctgatgg tgatacagta actctcatca
    25081 aggacttgaa agtaaaaggt gcgccaaaag atttgaaaca agggacgcgc gtgaaaaata
    25141 tccgcatcgt agaaggcgac cacaatatcg actgtaagat tgatggtttt ggtgccatga
    25201 aacttaaatc agagtttgtg aggaagattt aagcatgtca aaacactata aacttgtatt
    25261 ttatagccgt atcttcttgt ttctagcggc ttttacggga gtttatcttg aaattactaa
    25321 gcatggtggt tttgggatgc ttctctatta cacggttctg tccaacctct tggtaactat
    25381 ttttaccctt tatcttctaa aggttatgag ccgtgtaggt gaaaattggc aaaggccaag
    25441 tctcttgcgc ttaaaaggtg gggtcaccat gagtatcatg attacctgtg tgatttacca
    25501 tttcctcttg gcgcccattg cgactaattt ctatacccta gaaaatttcc tttgccacta
    25561 tatcgttccc atctggtttt tagcggatac cctctttttt gacaaacagg gtcaatacaa
    25621 gatttgggat ccagcagtgt ggaccatttt accctttctg tatatgatgt ttgctctttt
    25681 taatggcttg gttctaaaac tcaatattcc aaatgccaag gataatcctt tcccttactt
    25741 ctttttgaat gtgaacaagg gttggaatgt tgtgtttaag tggtgtctga ttatctttgt
    25801 tgcctatatg gtagcaggat ttattttcta ctttatcaag caaatcaaga gaaagtcatc
    25861 ctaatactct tcgaaaatct cttcaaacca cgtcagtttc catctgcaac ctcaaaacac
    25921 tgttttgaac aacctgcggc tagcttccta gtttgctctt tgattttcat tgagtataag
    25981 atacaaggga ttcattttcg aatttaagaa ggagtctaca aaccaatgag gcttcttctt
    26041 ttcttgctta tttgataact atcaaaaaag tagaagatta agagaaatat agaaagagat
    26101 ttcatgaaac aatttttaga acgggccagc attttggctc tctccctcgt tttgattacc
    26161 tccttttcca tttcgagtgc cctaccagcc atgtttgact attatcaggg ttattctaag
    26221 gaacaaattg agctcttggt gagcttgcct tcctttggaa tcatgatgat gttactgcta
    26281 aatggtttct tagaaaaaat atttcctgag cgcttacaga ttagtttggg cttgctgatt
    26341 ttatcattga gcggtacagc tcccttctgg taccaagcct atccctttgt ctttggaaca
    26401 cggcttctct ttggtttggg tcttgggatg atcaatgcca aggccatttc tattatcagt
    26461 gaacgctacc aaggaaaaag gcgaattcag atgttagggc tacgcgcttc tgcagaggtc
    26521 gttggagctt ctctcattac cttggccgtc ggtcagttgt tggcctttgg ttggacagct
    26581 atctttctag cctatagtgc tggatttttg gtgctgcccc tttatctgct ctttgtccct
    26641 tatggaaaat caaagaaaga agtcaagaaa agagcgaagg aagcaagtcg tttaactcga
    26701 gaaatgaaag gcttgatttt taccttagct atcgaagcgg cagttgtagt ttgtaccaat
    26761 acagctatta ccatccgtat tccaagtttg atggtggaaa gaggattggg ggatgcccag
    26821 ttatctagtt ttgttcttag tatcatgcag ttgatcggga ttgtggctgg ggtgagtttt
    26881 tctttcttga tttctatctt taaagagaaa ctgctcctct ggtctggtat tacctttggc
    26941 ttggggcaaa tcgtgattgc cttgtcttca tccttgtggg tggtagtagc aggaagtgtt
    27001 ctggctggat ttgcctatag tgtagtcttg acgacggtct ttcaacttgt ctctgaacga
    27061 attccagcta aactcctcaa tcaagcaact tcatttgctg tattaggctg tagtttcgga
    27121 gcctttacga ccccatttgt tctaggtgca attggcttac taactcacaa tgggatgttg
    27181 gtctttagta tcttaggagg ttggttgatt gtaatctcta tctttgtcat gtacctactt
    27241 cagaagagag cttaggattg attcctaagt ttttcttttg atactcaatg aaaatcaaag
    27301 agcatagttg attgagtttg gaatagtacg ctgtagctgc taaaatattt ctagaaatta
    27361 atttgacttt tctaatagag ttattcatat cttatttcaa tctactatag aaagctagcc
    27421 gcaggttgct caaaatagtg ttttgaggtt gcagatggaa actgacgtgg tttgaagaga
    27481 ttttcgaaga gtatgagatt tttataccca tacaatattt gttttaggtc cttgtttaca
    27541 gactaatttc ttgataaaat agaggttatg acgagatata aagcaactat ttcctatgat
    27601 ggttatgcct ttgctggctt tcagcgccag cctcatgcgc gtagcgttca ggaagaaatt
    27661 gaaaaaacct tgaccagatt aaataaaggg caagccatta ctgttcacgg tgctggtagg
    27721 acagatagtg gggttcatgc cctgggacag gtcattcatt ttgacctgcc ttatcagatg
    27781 gatgaggaga aactccgttt tgccttggat acccagtctc ctgaagatat tgatgtgatt
    27841 tcgattgagc ttgtggcaga tgattttcat tgccgttatg ccaagcatag caagacctat
    27901 gagtttactg tggatagagg acgtcccaaa aatccgatgc gccgtcacta tgccacccac
    27961 tttccctacc cactcgatgt ggaacgaatg cagattgcaa tcaaaaagct agagggaacc
    28021 catgatttta ccggttttac agcctctggg actagtgtag aggataaggt tcgcaccatc
    28081 acagaagcta gtttaatagt cgatgagaca ggacaatttt tgacctttac cttttcagga
    28141 aatggtttct tgtataaaca gattcgcaat atggtgggga ctcttctcaa aatcggtaac
    28201 aaccgcatgc cagtagagca gattgatctc atcttggaga agaaggacag gcaacttgca
    28261 ggtcccactg cagcaccaaa tggtttgtat ttaaaggaga ttcgttatga agaataatcg
    28321 tattttagca ctttctggaa atgatatttt tagtggtggt ggactgtcag ctgatttggc
    28381 tacctatacc ttgaacggct tgcatgggtt tgtagcagtg acttgtttga cagccttgac
    28441 agaaaaagga tttgaagtct ttccaactga tgataccatt tttcaacatg aattagatag
    28501 cttgcgtgat gtggaatttg ggggaattaa gattggtctt ctccctactg tcagtgtggc
    28561 tgagaaggcc ttggacttta tcaaacaacg cccaggagta cctgtggtgt tggatcctgt
    28621 cttggtctgc aaggaaacgc atgatgtagc tgtcagtgag ctctgccaag agttgattcg
    28681 ctttttccct tatgtcagtg tgattacgcc taatctccca gaagcagaat tattatccgg
    28741 tcaggaaatt aaaaccttgg aagacatgaa aactgcagcg cagaaattgc atgatttagg
    28801 agcgccagca gtcattatca agggaggcaa tcgtcttagt caggacaagg ctgtggatgt
    28861 cttttatgat ggacagacct ttactatcct agaaaatcca gttatccaag gccaaaatgc
    28921 tggtgcaggt tgtacctttg cctctagcat tgccagtcac ttgattaaag gtgataaact
    28981 tttgccagca gtagaaagct ctaaggcttt cgtttatcgt gctattgcac aagcagatca
    29041 gtatggagta agacaatatg aagcaaacaa aaacaactaa aatcgccctt gtatccctat
    29101 taaccgccct ttctgtggtt ctaggttatt tcttaaaaat cccaacacct acaggaattc
    29161 taactctttt agatgctggt gtcttctttg cggcctttta ctttggtagt cgtgaaggag
    29221 cggtagtcgg aggactagca agtttcttga ttgacctctt atcaggctac cctcagtgga
    29281 tgttctttag cttggtcaac catggcttgc agggattttt cgcaggattt aaaggaaaaa
    29341 gtcagtggtt aggccttatt ttagcaacta ttgccatggt aggaggctac gccttgggtt
    29401 ctactttgat gaatggctgg gcagcagccc tcccagaaat tctaccaaat ttcatgcaaa
    29461 atatggtagg gatgattgta ggatttattc ttagtcaaag tatcaagaag attaagtaat
    29521 actcttcgaa aatctcttca aaccacgtca gcttccatct gcaacctcaa aacactgttt
    29581 tgagcagcct gaggctagct ttctagtttg cactttgatt ttcattgagt ataaagaggt
    29641 tgagtaaaaa gtatttcaaa taagaaaaac gcatagtatc aggtgttgaa tgaactgccc
    29701 cccaaaaagt tagacagaaa aaatctaact ttttggggtg tttttattat gaaattaagt
    29761 tatgatga
//
LOCUS       DAVBCA010000024        28617 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.024, whole genome shotgun sequence.
ACCESSION   DAVBCA010000024 DAVBCA010000000
VERSION     DAVBCA010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28617)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28617)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28617
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.024"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(482..2209)
                     /gene="ezrA"
                     /locus_tag="VQU19_000997"
     CDS             complement(482..2209)
                     /gene="ezrA"
                     /locus_tag="VQU19_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HET2480258.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(2291..4237)
                     /gene="gyrB"
                     /locus_tag="VQU19_000998"
     CDS             complement(2291..4237)
                     /gene="gyrB"
                     /locus_tag="VQU19_000998"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HET2480259.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEVVGDTDRTGTTVHFIPDPKIFTETTTFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(4252..4815)
                     /locus_tag="VQU19_000999"
     CDS             complement(4252..4815)
                     /locus_tag="VQU19_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET2480260.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEDILNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(4900..5454)
                     /locus_tag="VQU19_001000"
     CDS             complement(4900..5454)
                     /locus_tag="VQU19_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HET2480261.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYRDVFGKNQ"
     gene            complement(5465..6688)
                     /locus_tag="VQU19_001001"
     CDS             complement(5465..6688)
                     /locus_tag="VQU19_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HET2480262.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVSLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(6725..9175)
                     /locus_tag="VQU19_001002"
     CDS             complement(6725..9175)
                     /locus_tag="VQU19_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HET2480263.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLEPRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIHISSTKSGRTLLSSL
                     LPESCQAMGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIIGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(9374..10303)
                     /locus_tag="VQU19_001003"
     CDS             complement(9374..10303)
                     /locus_tag="VQU19_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HET2480264.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELLVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARSLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVK"
     gene            10443..10730
                     /locus_tag="VQU19_001004"
     CDS             10443..10730
                     /locus_tag="VQU19_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HET2480265.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(10764..12098)
                     /gene="ciaH"
                     /locus_tag="VQU19_001005"
     CDS             complement(10764..12098)
                     /gene="ciaH"
                     /locus_tag="VQU19_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HET2480266.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(12088..12762)
                     /gene="ciaR"
                     /locus_tag="VQU19_001006"
     CDS             complement(12088..12762)
                     /gene="ciaR"
                     /locus_tag="VQU19_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HET2480267.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(12871..15417)
                     /locus_tag="VQU19_001007"
     CDS             complement(12871..15417)
                     /locus_tag="VQU19_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HET2480268.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHIAYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(15541..15981)
                     /locus_tag="VQU19_001008"
     CDS             complement(15541..15981)
                     /locus_tag="VQU19_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HET2480269.1"
                     /translation="MIPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQSVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQVHEDFFTDCLGEVGLTFTPESKVVLEEFRKVYPL"
     gene            complement(15956..16825)
                     /locus_tag="VQU19_001009"
     CDS             complement(15956..16825)
                     /locus_tag="VQU19_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HET2480270.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYRFTELTNTEANCLVGTKEFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSVIFPFVNDADQLKQAITVLRQYGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDLESPIMLDMLRDMQDKA
                     RKNKINFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(16867..17595)
                     /locus_tag="VQU19_001010"
     CDS             complement(16867..17595)
                     /locus_tag="VQU19_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2480271.1"
                     /translation="MELFKTWKKNMVLYGLKSQIGTVYRNNDRTTSFYDVGNFLYLAG
                     ELDSRFWEDFVRKYGLDYKIIISENTNWQDFLHRKVGLNSFTRYSFKDKANFQVEFLN
                     NLVTHLEEGYNIVPIDNHIYNCFSTEEWSQDLQGDFESYQDFVLKGGFGFVILKNNEL
                     IAGISSGLVYRKAVEVEVATRPNEQGNGFAKKLGAAMILESLNRDMFPLWDAHNEASK
                     KVAEFLGYELSEPYEAFELEEILI"
     gene            complement(17603..18082)
                     /locus_tag="VQU19_001011"
     CDS             complement(17603..18082)
                     /locus_tag="VQU19_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET2480272.1"
                     /translation="MEIKKHFGVYAVCLENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELTNFMVDHVMALYDVEMNESAPQV
                     TTSEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGFPELDKTSYMNWKVK"
     gene            complement(18093..18791)
                     /locus_tag="VQU19_001012"
     CDS             complement(18093..18791)
                     /locus_tag="VQU19_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HET2480273.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(18784..19050)
                     /locus_tag="VQU19_001013"
     CDS             complement(18784..19050)
                     /locus_tag="VQU19_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HET2480274.1"
                     /translation="MKNVELKEKNMTFEEILPGLKAKRKYVRTGWGGAENYVQLFDTI
                     EQNGLALEMTPYFLINVSGEGEGFSMWSPTVCDVLATDWVEVHD"
     gene            complement(19116..20042)
                     /locus_tag="VQU19_001014"
     CDS             complement(19116..20042)
                     /locus_tag="VQU19_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HET2480275.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFNLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCQLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSRAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(20117..20932)
                     /locus_tag="VQU19_001015"
     CDS             complement(20117..20932)
                     /locus_tag="VQU19_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480276.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPAPWDSLSVFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            complement(20936..21256)
                     /locus_tag="VQU19_001016"
     CDS             complement(20936..21256)
                     /locus_tag="VQU19_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HET2480277.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLTKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
     gene            complement(21553..21633)
                     /locus_tag="VQU19_001017"
                     /pseudo
     CDS             complement(21553..21633)
                     /locus_tag="VQU19_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(21677..23674)
                     /gene="metG"
                     /locus_tag="VQU19_001018"
     CDS             complement(21677..23674)
                     /gene="metG"
                     /locus_tag="VQU19_001018"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HET2480278.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEYDGKLTLLTVDPAVPNGSVIG"
     gene            complement(23798..25057)
                     /locus_tag="VQU19_001019"
     CDS             complement(23798..25057)
                     /locus_tag="VQU19_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2480279.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKKSKIYGFGGLP
                     ITTNISLAANFNIDEIASIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            complement(25059..25760)
                     /locus_tag="VQU19_001020"
     CDS             complement(25059..25760)
                     /locus_tag="VQU19_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2480280.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            complement(25744..26943)
                     /locus_tag="VQU19_001021"
     CDS             complement(25744..26943)
                     /locus_tag="VQU19_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HET2480281.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTAVKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAQAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILIPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            27229..28575
                     /gene="gor"
                     /locus_tag="VQU19_001022"
     CDS             27229..28575
                     /gene="gor"
                     /locus_tag="VQU19_001022"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HET2480282.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESIAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTASEEFVTMR"
BASE COUNT         8560 a         6297 c         5109 g         8651 t
ORIGIN      
        1 ctatcctatc ttctagaatg tcttccaaac gagaaaactc tcgtaaacaa agaggtttta
       61 gaggcctatt taccgtggac taaagttgta caagaaaagt gcaaataaga aatctccaga
      121 ttaggaacta tccgtgagtt ctctagtctg gagatttttc aatagacttc gttattggac
      181 ggttaccaag ttacttcaaa gtacagattt gaagctgcag ataagactga cgaaatcact
      241 ttaatactaa atgaaaatca aaaagcaaac taagaagcta gcctcaggct gtacttgagt
      301 acggtaaggc gacgctgacg tgatttgaag agattttcga agagtataaa acactgtttt
      361 gaagtggtgg ataaatcggc tgggtaaaaa ctcaatctca ggagaaaatg aagtaaatct
      421 ccccacaact atagaaaaag atttgattct gctcctcaca caataaaatc tttttctttt
      481 attaaaaacg aatcgtttca cgtgttttct catatgaggt aacaaagcga ttggttacac
      541 caggctctgc cacttccaat gcttgagaaa tcttgtcaaa tgaagcgtga taatcaaatt
      601 ctttttcaaa aatatctaaa gcttcgttaa atgcttcttg aatgcgttca tcaaatgagc
      661 gatagcggtt agaatattgc aagagttgct ctgtcaaagt tgcatattgt acaatattat
      721 aagtttccgt ttctaaagct tccatatcat tcgttgcaat ttcaagaact cgggtaacag
      781 attcaatgtt aatcattttt tgttctaact caaccattaa atcctcggta ttattgcttg
      841 ccgtaaagaa taacttcaag aaagtttgtg gaatacctgg cagattgcgt ttttccatgt
      901 atcgcttgat agtatggaga cgattgacat aaacattggc cttttgacgt gcattaatat
      961 catctttctc aatttgtgtc aggcgctcac taactgaaat ttgctcatct tcaatatctt
     1021 ttagttgagt ttgtaaatcc tcaagatttt cttcaagaac tgaataagct tgggttggtt
     1081 cttcttgatt tgaagttacc tcaacaatag ctgcctcaaa actctctaat tctgtctgaa
     1141 tacgacgaac atggcttgca gctgtctcag gaagtaaata ggtcttgttc aaacgtgcaa
     1201 tatcttctcc caataaagta ttattctctt tcatatgttg aaggtaagtt ggaagagttg
     1261 caagtagatt ttccactact ttctgagcag caatttctcg agtaaaaata tcatacaagg
     1321 cattgatttc ctcttgtgcc tgtccattct catattcggc attatccaat tccaactgac
     1381 gaatattctc ttggtttttc ttgaatgctt cataaagcaa gtggaaacgc gcttcaatat
     1441 ccgtttcaac aaaatgataa ttagcatcaa ttagtttacg ataaccggct tccaaatcct
     1501 gtaattgatc tggcaattct gtagaaagcg tcgtaaccaa ggctggaaca cgatccacaa
     1561 tatgacttaa ggccaaaatg tgattttctg tattatccaa aatcactgcg gcttccacag
     1621 ggtcacccga tgaattcaag gttacaaatt gtgaaaattc agattggata ttttctaatt
     1681 gtttttcaat ttcatccaag gcttgaccat actgttctga attttcagca actctatgct
     1741 gaagttcctc aaataaatcc aaagcatgaa gaacacgacc actattttta gattcttgct
     1801 tctctaagtc tgccaaagca ttgcgaattg ccgcaatatc ttcttcaatc aaagtaattt
     1861 gactctcaat ttggtcaatt tgatgactgg ccttgagaaa acgaaatgaa tggttataac
     1921 cttctgcttc aaagagatta ttttcaatat cggcaaaaga gttgagagat aaatcgaccc
     1981 atttttgatt ccattcacgg aaagccactt gactttgtcc aatcaagtgc atatttttta
     2041 cagcttctac ttcatcattt actggaagat tgtatagttc ttcttttctt tcttctagcg
     2101 cctctaatct cccctcgttt cgcttacgta gaaagattgc cactacataa gccagaacta
     2161 aaatgactgc aattgcaacc attaaataaa ttagttgtcc attagacata tcaaactcct
     2221 tttttacttg aaacaatcgt aacgattata tcatattttt tagaccaagg gaactacttc
     2281 tccctatttt ttagacatca agtgtactat agacagcatt ttcttcgata aactcacgac
     2341 gaggctctac tcgatccccc atcaacatat caaagatttt atctgcttct gcagcatcat
     2401 ctacagaaac tctagccatc aagcgatgtt cgggatccat ggttgtttcc cacagctgat
     2461 gatcgtccat ttcacctagc cccttataac gctgaatagt cggtttggta cgaccttcac
     2521 tataacgggc taaagcttct tggagtttga tttcttgatc tgcacccggc tggatatatt
     2581 ctttaatctc gcttccaacc ttgacaccat agattggtgg ttgggcaata taaacataac
     2641 cagcttctag gattggtttc atataacgat aaatcaaggt taaaagaagg gtacgaatat
     2701 gggctccatc gacatcggca tcggtcatca aaacgagttt ttggtaacgg gctttcgaaa
     2761 catcaaattc tgcgccaaat cctgttccca tggctgtgaa aagactacga atttcttcgt
     2821 tagctagaat cttatccata cttgcttttt caacgttcaa aatcttaccg cgaattggaa
     2881 ggatagcctg aaactcacgg ttacgaccag atttggctga tccaccagct gagtctcctt
     2941 cgacgatgaa gagttctgtt tcagcagggt tattagaaga acagtctgct agtttccctg
     3001 gaaggttgga aatttccaaa ccagattttt tacgtgtgac ttcacgcgca cgcttggcag
     3061 ccacacgagc cttggcagct aaaatccctt tttccacgat acgtttggca atctgtggat
     3121 tttccatgag gaaatcggag aaggcttcac tgaagaggcg attggtaatc ttgaccactt
     3181 cgctatttcc caatttggtc ttggtttgtc cttcaaactg tggatttggg tgtttaactg
     3241 agataactgc agttaatcct tcgcgaacat cttcccctgt taaattatct tcattgtctt
     3301 tcagtaactt attcttacga gcataatcat tgataacacg agtcagtgcc gtacggaaac
     3361 cttgttcatg cgttccacct tcatgggtat gaatattatt ggcgaaactc atgacatttt
     3421 catggtaacc tgttgtgtac tgcatggcta cctcaactgt gatatcatcc atctcaccgt
     3481 ctgtatagat tggtgtatca aagattacat ccttgttctc gttgatatat tcaacgtaac
     3541 tagcaatccc accttcataa tgataatgct tggtttgttc caaaccttgg cgcttatcag
     3601 tgatagaaat ttgaagaccg cgatttagaa aggccaactc ttgaatccgt ttatttaatt
     3661 tatcaaaatc aaaggttgtt gtttcagtaa agatttttgg gtccggtatg aagtgaaccg
     3721 ttgttccagt tctatctgta tccccaacca cctcaaggtc tgcaacaaca tgaccacgac
     3781 ggtattcttg gtaatgaatc ttaccgtttt tatggacatg aacgtctaat tgagtggaaa
     3841 gggcattaac tactgacgac cccaccccgt gaagaccacc tgaaaccttg tatccaccac
     3901 cgccgaactt tcctccagca tgaaggactg taaagacggt ctcaacagca ggacggcctg
     3961 ttttttcctg aatatcgact gggataccac gcccatcatc cacaacagta atcgaatcat
     4021 ctggctcaat aaaaacttga atatggctgg caaatcctgc caaggcctcg tcaattgagt
     4081 tatcaacaat ttcccagact agatggtgaa gaccttcttt tgaggttgat ccaatgtaca
     4141 tccctggacg catacgaaca gcctctaagc cctctaaaac ttgaatttga ctggcatcat
     4201 aatcctgtgc ctgcagattt ttgatttctt ctgtcatctt attccttttt cttatatgtc
     4261 taatacttgt cttaaattca cgatactggt aaacaagtgg gtatcaagtc ctgcagcttg
     4321 acctgcttcg atatcaatcg gccgatcacc aatgacaaga ccagagctaa tctgatactt
     4381 ttctcttaaa taaagcatgg attcgggatt tggctttctc ttaaagcctg agctagaagt
     4441 caccacttct gtaaaataag ctgctataga ggttttttct aaaatttcca aaacctgatc
     4501 atttcgatga gagaccaaaa aatgacggcc accttgattt aaaatgtctt ccaataggtc
     4561 agaaactcct tcaaataaaa tcgggtgttc aagctctctg gcttcatttt ccttgtactt
     4621 ttctaaaaaa ttctctaaat tgggagcgaa tgtctcaatc gcaaaaggag tagaaacctt
     4681 taaagcttga tagacactgt catggtcttg tgtgatacca tacagtgcca atgtttcaac
     4741 aaatgcagct gttgaagttt cataattatc cagtaaagtt ccacctaaat cccagatgta
     4801 atcgtgatat ttcataccct tcattatagc atttttttat gaaaaaagcg atgatttccc
     4861 tgagttttcc acataaaaaa cgagagaata actcccgttt tactgatttt taccaaagac
     4921 atctcgatag agcattcctg ttcgtaaact ctctgcgtcc cctcctagtt gctccaccaa
     4981 ctcgtaggca aaggcaaggg ctgttgaagg accccgactg gttgtcaact gaccatctac
     5041 cactactgtt tccttgacgt agtgaccatc aaggatttgc tcttgaacgc cgtcataaca
     5101 agtgtatcgc ttatttttca atatctctgc ttgattgagg gcaattggtg ccgcacaaat
     5161 ggctgctagt ttcttccctt cttgctcgaa gctttgcaat tcttgaatca aggtctgatt
     5221 atcacgtaaa tgtgcagaac caggcatacc tccaggaaga acaatcatat catagtctga
     5281 taaatctcca tcaaagacat gatctgctct tacttggatt gcatgcgaac ccgttacttg
     5341 ctcttcaaaa ccaaccatat cacatgtgat attggctcga cgcaagacat ctacaactgt
     5401 caaggcttca atttcttcaa agccctgagc taacataact gctactttta ccatgatttt
     5461 ctccttattt aatttgtttt aatacaacct ttttccgttt gaatgggact tttccgctct
     5521 tttcttcagc tagattagtc tggtaactca tcgataaaag caaaccaaca ccaatcagat
     5581 tactgataat agctgatccc ccttgcgaaa tgaaaggcaa gggaatcccc gtcaaaggaa
     5641 gtagtccagt cacagcaccg atattctcaa agatgtggaa gagcaacatc ataatcaaac
     5701 ctgtggaaat ataagtgtag aactggttat ttgatttaag agtaatcttc aacatacggt
     5761 aaatcaacat gagatagagg gcaataacca ggacagagcc aataaagcca aaatcttctg
     5821 caataaccgt aaaaatcata tctgactctc gaactgggat aagcagattc gaagcattaa
     5881 atccctgacc aaataagcca ccactcccaa tggcaatctg cccttgagcc tgctggtaag
     5941 tcgttgtttg ggcaaactca aagggattga gccaagccaa aatccgattg atttggtagg
     6001 tcggcattcc aatctggtga agaaaagctc gtccgtcctt gctaataaag atagctaaga
     6061 aaccagcaac tcctgttaca gcagtcacaa atactgggat aataattttc caagaaaccc
     6121 ctgataataa aacgattcct gagaaaatgg ctacaaaaac caaagccgtc cccaagtcac
     6181 tttgaagtgc taaaagaact aggactggaa tggtaaagag aatcatccag aaaattaaca
     6241 aaaagtccag cgaaaccgtg cgtctccatt ccttatgttt ctttgtaaat tggacaatga
     6301 cacgagccaa catgaggata taggatatct tcataaattc tgacggttga aatagggtaa
     6361 ttccatttat tgatacccag tttttggcac ccgttgatgc aactaagctt ggattataaa
     6421 atacaatcgg caagatcata agtcccaagc ctaaaatata tagaaagggg gtcaccttcc
     6481 aaagaaattc tgtattaaag agcatgacca caaaaccaat cacaagcccc aaggcaatcc
     6541 aggcgacctg ctgccctaaa atgggcagaa tattattggg ataatcatga ctaacggcta
     6601 tatagatagc caccacaccg atgaccagta gaaaaaatac tggcaagagc aaactataat
     6661 cgactctaga gtcgagagaa cgtttcatat atactaacct tatactttca tacaatacta
     6721 tttatcaaag ttcattaaaa aatctatcaa tagcctcgtc aacttcggat cgagagatgg
     6781 ttttaacagt cgcttcttct gctagagatg ctactatttg tttgccgtat cgttttccga
     6841 tgattctcct atccaaaata agagttaagg aacgttggta ttcacgtctc atacttcttc
     6901 ccaaagcctg ttttaaacga ataatggcca ttggcaattg ataatcataa aaggcatttt
     6961 tcccttcttg attcagttct tgattaatct ttttcgtcaa gggttcttga ggattttgga
     7021 aaggaagcct cggtacaact tgaatcacaa aaggatggct tgaaaaatca actccctccc
     7081 agaaacttgc tgcaccaagc aagatttgtt gttcaccttt ttcaaagcgt ttctttagct
     7141 gatgaacatc cccattttta tactgggcca agtggctaac tgtaagtaaa tccgatactg
     7201 ctagaagcat gtctttagcg gtaaagagaa ccaaaatcgg ttgctggaaa gcttgaattt
     7261 ccactagtaa agcagctacc tctctggcat agacttctaa ggaggtttct gttaccagag
     7321 ggaaatcttt gaccataacc acttcttgtt cctgttttcc ccgagattca atcttgacaa
     7381 atttggcttc aggatagcct aaaaggtctg ccaaagaaac cctctgacta atctcaagag
     7441 tagccgatac tcccatggct tggcaactct caggaagtaa agaggacaga agagtacggc
     7501 ctgattttgt agaagaaata tgaattttct tttgactcgt ttcagttact tcaagccagt
     7561 aatcaccttc agctgtaaaa tagcgaacca gctcatcaaa gccttctact tctaattctg
     7621 aaaaatactg atggagattg tccagagaat ctaagatatt tttcctagat ttaccagact
     7681 gaaattgttc tatcaagtag agacactcaa agcgaatact ttctagtatc cgttgttgaa
     7741 ccctgttttc ttctcctact aaagccttat caattaaatc gataatagat tgtatatcgt
     7801 aggtctcttg aagcagattt tctagagcta acaaaatctt ttggacttca tcaataatca
     7861 gtaaacggtc actgacaaat tcaggattat cttcaagtct ggtcacgaga taggcatgat
     7921 tagtcactaa aagcttgcaa gtctctgccc tttcttgact acgtttccaa aaatcttccg
     7981 tcacaaataa gctctgggat gataaattcc catcatgacg aaggtctgct agaaaatgtt
     8041 ggtaacgata gagttgcccg atttcatcca aatctcctgt ctctgtctca gtaagccaga
     8101 ccaagacttg cattttaaag cgtctaaata agcgattttc atcattttcc tgcaaggaat
     8161 gataaaaggc atccaacttc agataatttt gtggtccctt taagctatga atatctgtat
     8221 ggaacacttc cttgaggcgt ttaccttctt cttccatgat ttgattttga agaatctttg
     8281 tcggaacact aagaacaatt tgtcgctctt tggattgaga taaagcgggt aagagatagc
     8341 cataggtttt cccaatccct gtcggcgctt gaatcagaga gacaggttca tctttcaata
     8401 gcaagccaac ctctttagca aaactttctt gttcctccct cacttcaagg ttcaacagag
     8461 aaatattttt agaaaagtct tgagatagtt ttcgtggctc cagagaagct gccgttttct
     8521 taaaatacag accttgaact tggaccaagt ctggagaact caggatagat tggttgcgat
     8581 aagtttcctc aataaccagg taggactcat ataggagagc gtcagccatt tccagcaagc
     8641 gttccaagag acctttagga agctgagtca tcttttcccg taaaaaaaga agtaattctg
     8701 ctgtagcttg ggcatctgaa agggctgtgt gtgcgtgttt aagaggaatt cctaattctc
     8761 gacacaaaat cggcaagcta tatttttcca gttcagggaa aaagacctgg gccaattcga
     8821 ccgtatcaac acgagggttt cttagctcat agccttcaaa aaataaattt tccgccaaga
     8881 gattagcatc aaactgaaca ttatgggcta caaaaatccc atcctccacc aagtcaaata
     8941 tttttctggc aacttgcgaa aaatcaggtg cttgcgccag acgttggtct gtcaatcctg
     9001 tcagttcttt gatatgagca tccaagggtt catgtggatt gacatccgtc gtatagtgat
     9061 cgacgatttc tccgtcctca atcacgacaa ttcccacttg gataatttta gccttactac
     9121 ctgtgctagt tgcctctaaa tccaccacaa catagcgatt accaatcgtt ttcattataa
     9181 aaaattatac caaaaaaagg gccatttggc acctgcaaac ataggataat tttcaaactc
     9241 aagaacacta cttttcttaa aaatcccatc gaatagagca ttctagcctg ctgatttttt
     9301 aaaatagtga agaaatacga aaaattgaga gaagaaatgt tttcatcttc cttctctcaa
     9361 cgaatcatgt attttattta accatgtcag gatcgtagtc ataaaatcct gtatcaagga
     9421 aacggttttt agggtgaagt ttacgaactt cttcatccag caagaaggct tggtcatggc
     9481 taaagttgcc ctcttgaatc aagctacgcg cttggataaa gagttttgca atctcaacaa
     9541 agttctgacc aggagtgtag agcccttcta gtttccagcg agtaaagcca tgctccacca
     9601 attctgttaa tttgatcatc aaatcaaggt cattgttggc aaagatatgg gtcccatgat
     9661 tatcttcaaa aatggaatag tggctctctg gatcacttgg ctcagccaag aagaggtcac
     9721 gtttatgcgt cttttcatca tcgatatgtg taaagttata gtagttttgc aagagtggac
     9781 gtttagaatg atggatgacg ctagcaccgt aaaccaaaac ttcagcagga atttccaaaa
     9841 tctctggcat tttgaaaagt tcagctgatg gaatttcacg cgccaaaaca gcctcagatg
     9901 cgccagcctt ttgtccccag aagttaatct gacgactgct agttaccatg gttgaagcat
     9961 cgtagatggt cttaaatgaa taaccatcgc ggttaactac gtaaaagacg cctgcatccc
    10021 caatcgtaat atagtctgtc ttgatttctt ccaagaagtc taagaaaggc ttgatacggt
    10081 ccatcatatc ttggtgcatg agagcattga ccgcaacgag caattcctta ccagcatcat
    10141 gaaccaactt agcgatttca cgtaattggt cataactaaa ggtcgttggc agacgaaggc
    10201 caaaatcttt ctcaccgaca tagatacggt ctacgccagc ttcgagtagt tgttcaactt
    10261 gttcaatact ttcagcagtt gctgtaatga caatcttttc cataagaaaa attataccac
    10321 atttctccaa aatcatccat gctttgaaaa tgaaaaggga ctttattctt tttgtaacct
    10381 ttctgtaata attctctgcc gaaaaaatga taaaataggt atgtactgtt aaggagagaa
    10441 ttatgcccgt aagaaaatta caatcctatg aggtagacta tcaagaagaa ttaaaccagc
    10501 agcttcctca ttaccaagct tatacacctg aagcgcaatc tgatgccaat ctcaaggaaa
    10561 tcctattttt tattaatatc gctgtttttt gtatctgtat tgctatcttt agttttatct
    10621 ttttagcatt aaaattatca actgctcttg cctttgccgc agcaatcgga ttcagcttac
    10681 ttgttttaaa agttcaacgg tctattatca aacgaaaacg tagaagataa atccaaaata
    10741 tcgccccagt tggagcgata tttttatttt ttctttttag atggtgtctg aatggcaatc
    10801 ttcacttcaa agattgttcc cttgggttta ttatctttga cagtaacagt tccttttaga
    10861 gcatctacaa tttgcttggc tagggataat cctaaaccaa aaccaccttt ttgccgagtt
    10921 ctagccttgt ctactcgata aaaacggtca aaaattttct ttttatcttc tgtcgaaata
    10981 ccgattccat tatcagaaac aagtaaataa agattgcgat cggtcgccga gataagaaaa
    11041 tcaatttcac catcctcctc agtatacttg acggcattat cgaaaagaat ggtcatcagt
    11101 tgtttcagaa gaagctgatc tgtgacaatt gttcgatgga tacgattttc aaaacggaag
    11161 acacgattat tttccgaagc aatcatctcg tagtttgtga aagttgtatt aaaaaagcta
    11221 gttggaactt ctgcaagctc cggcttaatc ccatcatctc tccgagctaa gttcagcaag
    11281 cttgtcgtta aaaaacgcat atttcggact tcttccaaac tcgatgcaat gctttcgctc
    11341 acatccataa tggtagcttc tggcttacga aaaagggtct ctaagcgatt ttgcaaaact
    11401 gcgagtggag ttcgtaactc atgactggca ttttccacaa aagactgttg cttctgcata
    11461 ctctcaagca ggggcctaac actgacccta gctagataga gactggcaag taaagacaaa
    11521 atccagaaac tagccatcac gaccacaatc aattgctcat gcttttgact agcctgttcc
    11581 aactgactgg tattaatcaa gacagcagca tacttgatat tggttgaaac cgaactaata
    11641 ttggtctcca tcaaaatcac acgatagatt tcttcctgcc catagctatt aaaaacctga
    11701 atctggtaga tatgtcctag ttctttcttt tctaacttaa tcttatccaa gcccaaaaat
    11761 cgatttccag aaagaagttg agtaaagtct ttatcaaaga gaatgacttc cgtattggaa
    11821 ctgacattag gttttatttc tactttacta gcgtccgccc tagcattttc taaatcttta
    11881 atctcttctg ttgccctatt tatagccagc tgaataactg cttgaggatt ttcactcagt
    11941 ccatgaagct tatcgtccac cgaagtataa agactcgaat gcatgacttg taaaataatc
    12001 agagtcattg tagaaaaaat cagggtgaag acaccgaagt tgcggataaa ataactaaag
    12061 tcatccgcat accatgtttt tttaagttta ctgaacatct tttaaaagat acccaacact
    12121 acgcaaagtt tgcaaattct ctgcaaaagt ggttcccttt aatttcttac ggacttttga
    12181 aacatagact tcgacaaccg aaatcgttgt atcactatca aatccccata gacggtcaaa
    12241 aatctgcgtc ttaggcaaaa tcacattttg attttgaagg aaataaacta gtaaatcgaa
    12301 ctctttcccc agcaattcga caggagtatc ttcaacttta acggtattgg ttgataaatt
    12361 aaccacgata ttcccataag tcaaggtgtt ttcattaaac ttccctgaac gtttgagaag
    12421 ggcctgaatc cgcattttaa gttcttctag gtagaaaggt ttggtcagat aatcatccgc
    12481 tcccagttca aatccatgtc ccttgtcatc caaactttcc ttggcagtca taatcagaac
    12541 tggtgtcgta attccctttt cacgcaattc ttttaagact tggaaaccat ttttttctgg
    12601 caacatcaaa tccagcaaaa tcaagtcata gacaccactc tcagcttcgt agagaccttc
    12661 ttctccatca aatacctgca taacatccgc aaaatcgtct aaaaagtcaa atactgaatt
    12721 tgacagacct aggtcatcct caaccaataa gatttttatc atgagaaact cctccttatt
    12781 aaaactatta taccaaattt gccttaaaaa aaactcaact ctctgcattt tacatgagat
    12841 agctgagttt tctttttatt ttaggcttat ttatgcattt ccgtattgaa gaacaactgc
    12901 ttcgactgca gctttttcac ggctaatcaa gtcaacacgc gctgcaattt ccttgattcc
    12961 cataccgatg ttacggctaa gagcaaggtc agaaagttgc ggctcaaaga actccttgta
    13021 ttccgccaag cgttgctgag tcttaaatac atgagcagga aggataacaa agctatcaaa
    13081 gctcatatct cctccaaggg ctgccttaat ccaagcccag ttttcacgcg cccaagacca
    13141 agctgttttc tgagttgctt gatgagctag gaattggtaa taccaagcag acaagtcctg
    13201 tggtttgacc acaaatttgt ccttccaaga agtaatcaag ttttggatat tatccgcatc
    13261 tgtactgtat gcaagagctg ctgccaactg gcgtttaaag acagcatctg ttgcgtgagt
    13321 ataagtatca agataaagtg ctaacaagtc tttagtctca tgatgtttca tctcattaat
    13381 cagaacttgt gaacgaatag ctgctgggag tcctgcaaga ttctccttgt gtgttgcgaa
    13441 gatttggcta gcgacttgac tagcttctgc atcatttgag cgaatcatca tcgaaacagc
    13501 cagctgacga accaattcat cctcatctga ttctccgtct ttagcttcaa aaccaagacg
    13561 gtcatagtta tgacgagcca atttagcaac cagtcctttg aaggctgttt cagcatccgt
    13621 tccttcatca ataaagcgct caagggctga aatcacttga gaaacagctg aaaccaccag
    13681 ataagactct tccttagcaa gtttatcaag aactggaagc aagtctgcat aagcaatgtg
    13741 ccctgcctca gccaacaaac gacgttcttg aacaatttgc agtttgcttg tgttatcaag
    13801 tgtctctagc tcagcaagaa cagcttctaa caagtctcct tgatagtcgg taatatagtg
    13861 ggcagtattt tcagtgttga gacgaagagc tccttcattt tcagcaagaa gagctgcgta
    13921 gccagggatt tcgatacttt cagtttcgag tgtatcaggc aagcctttcc agttgctatt
    13981 gaggggcacc acccagagac ggttcttgtc ttcgttctca ccgatgaaga attgtttttg
    14041 tgaaatcttc aagacatcat tttcaacttt aacagtaaga actgggtaac caggctgttc
    14101 caaccaagaa tccatgaagg ctgcgacatc acgtcctgac gcttgaccaa gggcatccca
    14161 aaggtcacta ccaatggtgt tgctgtattg gtgtttttca aagtaggcgt gcaaaccttt
    14221 agcaaaatca gcatctccta gccaacggcg aagcatgtgc atgagacggc ttcctttggc
    14281 atagacgata gcgccgtcaa agagtgtatt gatttcatct ggatgtttaa cttcgacgtg
    14341 gacagactga acgccatcag tagcgtcacg ttcaagagca agaggtactc cacctgtttg
    14401 gaaatcttca aagatattcc agcttggttc gatggtatcc acacagacgt attccatcat
    14461 attagcgaaa ctttcattga gccaaaggtc atcccaccat ttcatagtca cgaggttccc
    14521 aaaccattgg tgagccaatt catgggccac aacaagggca acttgttgac ggctagcaaa
    14581 tgtagagttc tcatcgacaa ccaagtaaac ttcacggtag gtcacaagac cccagttttc
    14641 catagcacca gctgagaagt caggaagggc gatgtggaga gattgaggaa ttgggtactt
    14701 aactccatag taatcttcgt aaaactcgat agagcgaaca gcgatatcca gtgagaaatc
    14761 aagatttgaa agtggatgtg ctttggttga gtagacacct accagggtac catttttagt
    14821 tttagcggtc accccttgca aatcaccagc aacaaaggcc aacaagtaag aagacatgcg
    14881 aggtgttgtc tcaaacttcc agatacctgt ttccttacgg ttttcaacat cgatttctgg
    14941 catgtttgac aaggccaatt caccttctgc ttggtcaaag cgaagagaga ggtcaaaagt
    15001 tgctttggct tcaggctcat ccacacatgg gaaagcttcg cgcgcaaaat ggctctcgaa
    15061 ctgagtagac aagacctcct tcttgactcc atcaactgta taataagaag ggtaaatccc
    15121 tgtcatgttg tctgtaattt taccagaaaa ggcaagaacc aattcaactt gaccagcctc
    15181 agccaattcg atatgaaggg cttcattgtc atggtcaact gtaaatggac gagcttgacc
    15241 tgcaacttct acagaggtga tttccaagtc tttttggtgg agggagatgc ggtcactctg
    15301 tgcttgacca gtgatggtca ctttcccaga aaaagtcttg gtctcacgac tcaaatctaa
    15361 aaataaatca taatgttcag gaacaaattg cttaataaaa tgttcaactg cttgcatagt
    15421 tttctcctat tctaagttta agagctactg ctcttcttca aacaaactta ttatatcata
    15481 ttttgcttga gaaaaaagga ttggacagcg atttccaaaa ctttcttcct tctaaatagt
    15541 ctacagtggg tagaccttgc gaaattcttc taaaacaacc ttgctttcag gtgtaaaagt
    15601 cagccctact tcacccaaac agtctgtgaa aaagtcctca tgaacctggc gccaataggc
    15661 aagtgatttg tctccctcac cttccttaaa ggcatgttgc gcagaaactt gattgaagag
    15721 ttcaacagaa acctttgtaa tttcgacaat gcagacagac tgattttgac tatctaaaat
    15781 gacatcgaag gtccctactt ggggaagtgg ttcgtcttct agtacataga ggtcataggc
    15841 tgatgctgtt gctgtctttt ctcctttaaa caccaaatcc gctaaaaggt ctggttcaac
    15901 tccaaaagcc caagcatcga tttcatctcc gatcaaagga ttgatttgct tgtatttatt
    15961 ccacatttct tgcggtatca tgggtactcc tttgtaattt tttactttct tcttttatgt
    16021 gtttaagatg atctggatgg tcaatctcta aatcaaaaat ctctggaata gaactgtagt
    16081 ggataatgca cttgataccc aactgattca ttttttgtat gaaagaagta ttcagatagc
    16141 ctgctacagc aaaattaatc ttgttctttc ttgctttatc ctgcatatct cttagcatat
    16201 ctaacattat tggactttcc agatcatgcc attgactgtt tctcatagtc gcaaaaacaa
    16261 aggaagtcaa atcattcatt ccaactacaa tctttgaaat gcccgtttcc agtatactag
    16321 ataagtcaaa atacgctgac ggtaattcaa tcatcgttcc gactttccca gtaaagccat
    16381 actgacgcaa tactgtaata gcttgtttta attggtcggc atcattgaca aaaggaaaga
    16441 taacagatag attggggttg gtttgataaa cttctgtaac gacatgtgct tcagcctgaa
    16501 attcatccaa acacgccagt aaacgcctgg ttcctctata gccaaacaag ggatgccctt
    16561 cgtcaaaaaa ctctttagtc cccactaaac aattggcttc tgtattcgtt aattcagtaa
    16621 aacgatacca aacttcttca tctgagtaca gggagcagat agtctctaga taatctttta
    16681 caaattgctg acaacttgct aatatgatgt tttgattaag ctctctcaac aaatattccc
    16741 cacgaatcat gccgacgtgg tgaaatagtt gaggataaat tttttcaaga attttttcgc
    16801 cactaagggc aagttgattt ctcatagcca ttcacctcgt cttaaaagat acaatatcat
    16861 atataattat atcaaaattt cctctagttc aaaagcttca taaggttcag ataactcata
    16921 tcctaaaaat tctgctactt ttttggaagc ctcattatga gcatcccaaa gtggaaacat
    16981 atctctattt aaactctcta gaatcattgc agcaccaagc tttttagcaa atccatttcc
    17041 ttgttcgttt ggtctagttg caacttccac ttcaactgct ttacggtaaa ctaaccctga
    17101 ggaaatccca gcaatcagtt cattattttt aagaatcaca aagccaaatc caccttttaa
    17161 aacaaaatcc tgataggact caaaatcccc ctgtaaatcc tgtgaccatt cttccgtaga
    17221 aaagcagtta taaatatgat tatcaatagg cacaatattg taaccttcct ctaaatgagt
    17281 aactagatta tttaaaaatt caacttgaaa atttgcctta tctttaaaag aatagcgagt
    17341 aaaagaattt agccccactt ttcgatgcag aaaatcttgc caattagtat tttctgaaat
    17401 aataatctta taatctaaac catattttct aacaaaatct tcccaaaatc tggaatccaa
    17461 ctcccctgct aggtatagaa aattcccaac atcataaaag cttgttgtcc tatcattgtt
    17521 tcggtagaca gttccaattt gagatttaag accatagaga accatatttt tcttccatgt
    17581 tttaaatagt tccattatcc ctctacttca ccttccaatt catgtaagaa gtcttgtcca
    17641 gttctggaaa tcctaataat tcagacttaa ccttcaagac taatggcgat gcattttctt
    17701 ctgtaatctc ttgaatatcc atccaaatat atccaagtga atcattcgca ccatcagaca
    17761 cagcttccga agtcgtaact tgaggtgcac tctcattcat ttcaacatca tacaaggcca
    17821 tgacatggtc aaccataaaa tttgttaact cttctctgac gaaaacatcg tagattcgag
    17881 gattagagta gcttctaaca gtaaatcccg tctcttccat aacttctcta gtcagcgttt
    17941 ccgtcagtcc ttcaccaagt tgctgactgc ctccaggtag atcataccga tgttgataag
    18001 ggcctctcgt tttttcaatg cagagtaact tcccattttc taagcaaaca gcgtagactc
    18061 caaagtgttt tttgatttcc atccaactcc tcctacttca aagaccagcc accatctatt
    18121 gtcaagattt gtccttgcat ggcgctcgct tttccacttg ctaaaaaaag actaagctct
    18181 gctatttcct ctggctcaat ccagcgcttg attggagttt cactagccac ccagtcagcc
    18241 aaaccacctg gttcaaaatc cgcagcggtc atagctgtct tgactgctcc tggagcgata
    18301 ccaaagacct gaatcccagc ttcagcatag tctagagcca actgcttggt gaagccagcc
    18361 aaggcatgct tggatgaagt ataggcgtga ccacctccac ctgctaggct agaagcaatg
    18421 gaacacatat tgatgatgat tcccttttta ttttccagca tttgtgtcaa ataataccga
    18481 gtcaactcta ctggaataat gtagttgatt tcaaaaatct cttgaatgtc ctgcgccgtt
    18541 tgttccaaca gtggtttgta atcatccaaa actccagcag tattacacaa aacatccacc
    18601 tgagggcacc agtcaaaaat aggttccaag tccaaggtca aatctctctg taaaaagtga
    18661 aaatcaccct ctaagagtgg cttttcacct tggtcaactc cataaacttg atagcccttc
    18721 tctaaaaaga ggcgagcttg agccaatccg atccctgaac tcactcctgt aatgagtaca
    18781 cgtttagtca tgcacttcta cccaatccgt tgccaaaaca tcacaaactg tcgggctcca
    18841 catggaaaaa ccttctcctt cgccagaaac gttgattagg aaataaggtg tcatttcaag
    18901 tgcaagccca ttttgctcga tggtatcaaa gagttggaca tagttttccg cacctcccca
    18961 accagttcgt acatattttc tcttagcctt taacccaggc aggatctctt caaatgtcat
    19021 gtttttctcc tttaattcta cattcttcat ttaattatag caaaaaaccg ctttatacgg
    19081 ctttttgaat gtgagttatt caaacctgct actacttacg gcaaattatt ccctgcagca
    19141 agataaattt cataccattc ttttcttgtt aagctaaagt ttgccgctcg gctaacttct
    19201 ctcaagtgct taggatttgt tgtacctacg actgcctgca tttttgctgg ataacgcaat
    19261 atccaagaaa tggcaatagt tgaagaggtt actccatatt taatagctaa acgatcaagt
    19321 acttgattta aagcttgaaa tttctcattt ccaacaaaat tccctttaaa atacccgaat
    19381 tgtaagacag accatgcttg aatgaccaca tcgtgtaatt ggcaatattc aaaaatgctg
    19441 ccatctcgca tagctgcttg actatcttcc atattaacat gaaaagctga ttcaaatcct
    19501 ggagtaaaag ccgcactcaa ttgtagctga ttaacagcta acggctgctt gacatctttt
    19561 ttaagcaact ccatcatcat aggattttga ttagaaactc caaaatctcg aactttacct
    19621 tgtttataaa ggagattaaa ggcttctgct acttggtcag attccatcaa agcatctggt
    19681 cgatgaagga gcaagctatc tagatgatca atcttcaatc tttgcaaaat accgtctact
    19741 gattttataa tatagtcctt agaaaaatca aaataggtaa attcttcaat gcgaatgcca
    19801 catttggact gaatccacat cttttctctt aaatctggac gattttttag gacaagacct
    19861 aacagttctt cacaacgacc acgaccataa atatcagcca agtcgaaggc attgattcca
    19921 acagaaagtg ctgtttctac aagctcttca acttctttta cagacttatc ttttattctc
    19981 atcattccga gaacaatttc tgataattct ttgtcatctt gaccaagagt tatgtatctc
    20041 atcaaatttt tctcctttaa tttctaacat tcttcccttc attataacaa aaaaccgctt
    20101 tgcaacggct ttttgactat acttcactcc attttatctt cttaaaccca cggaacaaga
    20161 caaagattcc aataaagagg acagctaaag gaataacttt tgtaaggaaa acatttgaaa
    20221 ttcccatcca ctcataataa cggagcagag aacccaccac aagatgggca ataatcatac
    20281 tgacaaatgg acgaaagacc gcttctttcc aattccaaat accgataact agcgaaatcg
    20341 taaagacaga caaactatcc cagggagccg gaatataaaa ggctccttct tgtatgaagc
    20401 ttgccattcc tacatatcct aaaacaacta gaagaactat agtcccaaca acaatgtaag
    20461 tgccaatttt cattttagga gaatcttgga ctaaacttct tcgtaaaatt gtggccacaa
    20521 gtccaaatcc aatcagaaaa ataagaagtt gccctaaaaa tgtgagcaaa ttgactgtta
    20581 agagaggacc tttagaaaaa tcacttagta gttgataata acgtaataca gccaggacaa
    20641 gaattggcgt caaaagggac tctttgatag aactgcgagg tgctcccttg agaatctctt
    20701 tcattatttt tttaggattc ttacctagat aatcctctgc actcatgcca tctcgttctg
    20761 cttctgagaa atctagcatc atcaaataga tctgctctct gagatagtct tcatcataga
    20821 gaaatccagc aagattaaaa ctttcccaca actcctcaaa atacttttga ttctcctcag
    20881 aaaactcatg tagcaaagcg cttgtttctt cgtaatactt cattttcttc atggtttaac
    20941 ccccattctt aatcccttct actttttgac tcaaatcgtc ccattgctgc caaaagactg
    21001 agacacgctc ttctccttct ttcgttaatg aaaaatactt ccgatctgga ccatctggcg
    21061 acgggcgcat gtcgcctctt atccattgat ttttttctaa cttttgcaac aaaggataaa
    21121 tagttcctgg aacgatagta tcaaatccag cctctcgcaa agtctgaacc aactcataac
    21181 cataccgctc tttttgacca atcatatcca agacacaacc ttcaagaaca ccttttaata
    21241 gctgagtttc tttcatcact tctcccttct aatctatttt gtaataccta ctagtaactt
    21301 cacctatagt atattacttc tacactagtt tgtaaagcat aatagttaat actcttcgaa
    21361 aatctcttca aaccacgtca gcgtcgccct accgtatgta tggttactga cttcgtcagt
    21421 ttcatctaca acctcaaaac agtgttttga gctgacttcg tcagtttcat ctacaacctc
    21481 aaaacagtgt tttgagctga cttcgtcagt ttcatctaca acctcaaaaa catgttttga
    21541 gctgacttcg tcagttctat ctacaacctc aaaacagtgt tttgagcaac ctgcggctag
    21601 cttcctagtt tgctctttga ttttcattga gtataaataa aaaaacagaa ctagtctgaa
    21661 ctagtcctgt ctacttttac ccaatcacac ttccatttgg tacagctgga tcaactgtga
    21721 gaagggttaa tttgccatca tattcagctg atagaatcat accctggctg acatattttt
    21781 tcatcatttt acgtggtttg aggttagcaa cgatttgaac tttcttgccg accaattctt
    21841 gttcatttgg atagtatttt gcaattcctg aaagaatctg acgatcttct ccatcaccag
    21901 catccaagcg gaattgaagc aacttatctg aaccttctac tttagacact tctttgactt
    21961 ctgcgacacg gatttcaacc ttgtcaaagt cttcaaactt gatttcatcc ttgtttagtt
    22021 tgagctcaac ttcgtccgga ttccattctt tttcgactgc tggtttattg ccttccattt
    22081 gttccttgat ataggcgatt tcttcttcca tatttagacg tggaaagata ggtgttcctt
    22141 tggcaactac agtcacatct gctgggaagt cagccaaact caagttttca agactagaaa
    22201 cttcttccaa accaagttga gtcaaaactg cacgactagt ttccatcata aatggttcaa
    22261 tcaagtgagc aactacacga atgctggctg ccaagtggct catgacactt gccaattggt
    22321 cacgaagagc ttcatccttg gccaagaccc atggtgcggt ctcatcgatg tatttattgg
    22381 tacgagagat cagagtccag actgcttcaa gcgcacgtgg atagtcaact gcttccatgt
    22441 gtgtatggaa gtctgcgatt gattgttctg caacctcagc aagaacatga tcaaattcag
    22501 tcacaccttc tacataggca gggatttgtc catcaaagta cttattaatc atggaaaccg
    22561 tacggttaag gaggttccca aggtcattag ccaattcata gttgatacgg ccgacatagt
    22621 cttcaggagt aaaggttccg tctgaaccaa ctggaaggtt acgcatgagg tagtaacgaa
    22681 gtggatctag tccataacgc tctaccaaca tttcagggta aacgacattc ccttttgact
    22741 tagacatttt tccgtctttc atgacaaacc aaccatgggc aatcaaacga tcaggtaatt
    22801 taacatccaa catcataaga aggattggcc agtagataga gtggaagcga aggatatctt
    22861 ttcctaccat atggaagact gttccattcc agaacttgtc aaagttacca tgttcgtctt
    22921 gagcgtagcc aagagctgtc gcatagttaa gaagggcatc aatccaaacg tagacaacgt
    22981 gttttggatt tgatgggaca ggcactcccc atgtaaaggt tgtacgagat accgccaaat
    23041 cttccaagcc tggctcgatg aagttgcgta gcatttcatt aaggcgacca tctggcgtga
    23101 taaattcagg atgagctttg aaaaattcga ccaaacggtc ttggtatttg ctaaggcgaa
    23161 ggaagtatga ttcttcagaa acccattcaa cctcatgacc tgatggagca ataccaccag
    23221 tcacatttcc agcttcatca cggaaaactt ctgccagctg gctttctgta aagaattctt
    23281 cgtctgatac tgaataccaa ccagagtatt cacccaagta gatatcatct tgagcaagta
    23341 agcgttcaaa gacctgtgcg acaacttttt catggtagtc atcggttgta cggataaatt
    23401 tatcgtatga gatatctagt aattgccaga gttctttaac tccaaccgcc attccatcaa
    23461 cataggcttg aggtgtaata ccagcttctt ccgctttctg ctggattttc tgaccatgtt
    23521 catcaagacc tgtcagataa aatacatcgt agcccatcag gcgtttgtaa cgtgctagga
    23581 catcacatgc gatagttgtg taggcagaac cgatatgaag tttcccagat ggatagtaaa
    23641 tcggcgttgt aatataaaaa tttttttcag acataatttt tcctttccag gcaaatgaaa
    23701 cctgtttttc taacacttca ttatatcaca tttttaatga atttcgatag ggaaatccat
    23761 acaaaaacaa gatagacgag tgtccatctt gttgatctca ttcataacga agggcttcaa
    23821 ttggatcaag tttcgatgcc ttgttggctg gcaagactcc aaaaatcata ccaacactag
    23881 ccgaaactgc aagactaaat agggcaactg ggattgatac tccaacttct ataccttcta
    23941 ttaaaccttg cagtaacaaa cctgctaagg cagttaaacc acttgcaatt gtcaagccaa
    24001 ttaagccacc taacaaggtc aaaatcatgg attcaatcaa aaactgaatt aaaatattgg
    24061 cacgtgttgc acccaaagct ttacgaagac caatctcacg agtgcgctct gtcaccgaaa
    24121 ccagcatgat gttcatgaca ccagttcctc caacaaagag agaaatccct gcgatggaac
    24181 taataatcgt cgtcataaaa ctaaacgatt gttgaatttc tgcaaataca acggactcat
    24241 ctgccacctg gtattctccc tgttgtaagc ctgcaagctc tgtcattttt cgtgccagtt
    24301 ctggacccag agttggggtt aaactggtat cattcactcg aaagacaata ctagctattt
    24361 catctatatt aaaattcgca gcaagggaga tattggtagt aataggcaag ccaccaaacc
    24421 catatatttt tgacttttta gcctccggac tagtataaac cccaatgacc cggtaactaa
    24481 atccattgac ttctacaacc ttgttaatag cctcttgagg agattcaaat aaactaatgg
    24541 acaattcctc atctagcaaa ataacacttg caaactcttt gaaatcttgc tctctcagac
    24601 tacgacctgc aataatttca ttcttaacag cgtccatgta agttctgttt ccacctgtca
    24661 aattagcatt ctcaaccttt ttatcttgat aggtcaagat ggcattcgtt gaattggtta
    24721 catagtaact atccactccc ttcagtttag ctgcctcttg aacccaggat tcttgcggtt
    24781 ttggcggttc aacaggaact tcctcttcct ttccagaaac cgtaaaagct gattgtttct
    24841 gagtaaaaga cccatcttta ctttttttag gagagaaaaa gacgctaata tttttctgag
    24901 atttagtcat atctttattg acttgacgag atagggaatc acccaaagcc ataatcacaa
    24961 caactgatga aacaccgata ataatcccaa tcatagtaag caaagaacgc atcttgtgag
    25021 ccatgataga tgaaaaggca aatttcagat tctgcatctt agttttcctc ctttcctaac
    25081 tgagcactgt cagacgaaat gaccccatcc cgaatgacaa tctgacgttt ggcataggca
    25141 gcaatctcag gctcatgcgt taccatgata atggtttttc cttctttatt caaatcaacc
    25201 aataattgca taatttggtt acctgttttg gtatccaagg ctcctgtcgg ttcatccgct
    25261 aggataatag aaggattgtt taccaaggca cgcgcaatgg ctacacgttg cttttgacca
    25321 ccagataatt ctgaaggtaa atggtgacta cgttctgtca attcaacctt gtctaaatat
    25381 tcctcagcca acttgcgacg ttttgaagac gaaactcctg cgtaaatcaa gggcaattct
    25441 acattttgca gagcattgag cttcgataga agaaagaact gctgaaagac aaaaccgatt
    25501 tgttggttac ggaccttagc tagttgtttt tcaccaagcc cagccacttc ttgaccttca
    25561 agataatatt ctccactggt tggtgtatcc aacatgccaa tcgtattcat cagagtggac
    25621 ttaccagacc cagatggtcc catgatggct acaaattcac cctcattcac ttctagattg
    25681 atatttttga gaacctgcag ttcttggtca ccattacggt aacttctgaa gatatttttt
    25741 agactaatta gttgcttcat cagccttcac ctcttttcct tcttccaagg aagatgttgg
    25801 attactgatg accttagcac cgttcgttaa accagaagtg atttcttgat tttctgcgtc
    25861 agcatttccc aatgaaacct caactttttt agccttttgt tgttcatcca caatccagac
    25921 ataattttta ctatcatcca ttactagact gctaacagga ataagaatag ccttagtttt
    25981 gcttttaacc tcaatgttga cagaaaaacc ttgtttcaaa tcaccaacct cgcctgtcac
    26041 atcaatagta taagggtatt tagaacctgt attattcccg gctgctggac tagctgcttc
    26101 accattgttt ttaggatagt cagaaatata gcttaatttc ccagtccatt ttttatcagg
    26161 atacacttta gaagtaaagc ttacttcttg acctacagaa aggttggcta gattgtactc
    26221 agacaattct cccttgactt gtaaattttc attgctgaca atatgaacca taacttgact
    26281 cgcccctgtt ggagatttag aaacattgct attgacttcg actacagttc cctctagggt
    26341 actgagaaca gttgttgcat ccaattgact ttgagccttg cttaattgcg ctgcagcatc
    26401 tgcacgcgca tcacgggcat cacccaattg agcatcaata gaagcaacag aatttccagc
    26461 cactggagtt gggctttgca ccgttgcatc ttctcctcct actggcgctg gtaactgtgg
    26521 agcctgagct gaagcggctt catttcgtgc ttgattgagt tcattgatat gacgatctgc
    26581 cttagctact gctcgactag ctgaatcata ggccgcctgc gcttctgaac tactgtactt
    26641 gactaaagcc tgcccttcgc tgaccttatc gcccacagaa acaaggattt catctaaatc
    26701 acccttacta gcatcaaaat aaacatattg ttcatttttt gctgttactg tccctgacaa
    26761 taaaacagag gatgccacgc ttccttcctt ggcaacaaca agatgagtag gctcatcttt
    26821 tacagcagtc tgagaaggtt gtctaaaaag taaaatcccc ccggcaccca atacaactac
    26881 actcgcagca ccgattgctg catacagttg ccacttttta gctttaccat tctttttctt
    26941 cataatgaaa ctccttttct tttttacaat actttgctat tataccaaat ttccctccag
    27001 caaacaatgc agttcagatg gaaataatgg cagttcagga ttaaacaatc gttcggaatt
    27061 ttgcttttct attgtactag atatataata cactatcttg acttatttgg caagcttttt
    27121 tgcaattttt tgtgcgtagc agatttttgc aatcaaatca aaaaaagaat aaaatataac
    27181 tatcaaaaaa gacactctac tatttaaaag attacaaagg agttttcaat gagagaatat
    27241 gatatcattg ctatcggtgg aggtagcgga ggaatcgcta ccatgaaccg tgctggtgaa
    27301 catggagcca aagcagccgt tattgaggaa aagaaattag gtggaacctg tgtcaacgtc
    27361 ggttgtgttc ctaaaaaaat catgtggtac ggggcgcaaa tcgctgagac tttccatcaa
    27421 tttggagaag actacggctt taagactact gatcttaact ttgactttgc aaccctacgt
    27481 cgcaatcgtg aagcctacat tgatcgcgct cgttcttctt atgatggtag ttttaaacgc
    27541 aacggtgtag acttgattga aggtcatgct gaatttgtag attctcatac tgtaagcgta
    27601 aatggtgaac tgattcgtgc taaacatatc gtgattgcta caggtgccca tccaagtatt
    27661 cctaatattc ctggtgctga gctaggtggc tcttctgatg atgtatttgc ctgggaagaa
    27721 cttccagagt caattgccat tctaggcgct ggttatatcg ccgttgaatt agctggcgta
    27781 ctccacactt ttggtgtcaa gacagatctc tttgttcgcc gcgatcgtcc tttacgtggt
    27841 tttgattcct acatcgttga aggtttggtc aaggaaatgg aaagaacaaa cttaccactt
    27901 cacactcaca aagtccctgt caagttagaa aaaactactg acggcattac cattcatttc
    27961 gaagatggta ctagtcacac agctagccaa gttatctggg ctacaggtcg ccgtccaaac
    28021 gttaagggct tgcaacttga aaaagctgga gtgactctga acgaacgtgg ctttatccaa
    28081 gtggatgaat accaaaatac tgttgttgag ggaatctatg ctctaggtga tgtaacgggc
    28141 gagaaagaac tgactccagt tgcaatcaag gccggacgta ccctatctga acgtctcttt
    28201 aacggaaaaa ctactgcaaa aatggattac tcaactattc caactgttgt cttttcacac
    28261 cctgctatcg gaactgttgg tttgacagaa gagcaagcta ttaaagaata cggtcaagac
    28321 caaatcaagg tttataaatc aagctttgca tctatgtact ctgcttgcac tcgcaaccgt
    28381 caagaatccc gtttcaaact cataacagct ggttcagaag aaaaagttgt cggacttcat
    28441 ggaattggct acggcgttga tgaaatgatt cagggatttg ccgttgctat caaaatggga
    28501 gcaaccaagg ctgactttga tgcaactgtg gcaattcacc caactgcatc tgaagaattt
    28561 gtaaccatgc gttaatcgaa acaaaagaag ctgatataaa tatgtctgct tcttttt
//
LOCUS       DAVBCA010000025        28408 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.025, whole genome shotgun sequence.
ACCESSION   DAVBCA010000025 DAVBCA010000000
VERSION     DAVBCA010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28408)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28408)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28408
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.025"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            380..1333
                     /locus_tag="VQU19_001023"
     CDS             380..1333
                     /locus_tag="VQU19_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET2480283.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGATFLISLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGL
                     KYLKSDGYAIFLAPSDLLTSPQSDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            1384..2574
                     /locus_tag="VQU19_001024"
     CDS             1384..2574
                     /locus_tag="VQU19_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HET2480284.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGTDAIVFTAGVGE
                     NAENFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            2723..3094
                     /gene="rnpA"
                     /locus_tag="VQU19_001025"
     CDS             2723..3094
                     /gene="rnpA"
                     /locus_tag="VQU19_001025"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HET2480285.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            3069..3893
                     /locus_tag="VQU19_001026"
     CDS             3069..3893
                     /locus_tag="VQU19_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HET2480286.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAKIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            3912..4898
                     /locus_tag="VQU19_001027"
     CDS             3912..4898
                     /locus_tag="VQU19_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HET2480287.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QTENQDLKEMGLKVEQSYDIAQVATDVTAYVQAIVDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNRYSKTFYVTINVNDYVEHRAEVLQTYAQKL
                     AIRVLEEGRSHQTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            4949..5572
                     /locus_tag="VQU19_001028"
     CDS             4949..5572
                     /locus_tag="VQU19_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HET2480288.1"
                     /translation="MLNKIRDYLDFAGLQYRNPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPGWQLQQTSQWMNQAQRLRPHFWVYLQRDEQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQAKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            5703..7160
                     /locus_tag="VQU19_001029"
     CDS             5703..7160
                     /locus_tag="VQU19_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET2480289.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            7183..7464
                     /locus_tag="VQU19_001030"
     CDS             7183..7464
                     /locus_tag="VQU19_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET2480290.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            7541..8026
                     /locus_tag="VQU19_001031"
     CDS             7541..8026
                     /locus_tag="VQU19_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET2480291.1"
                     /translation="MNLKQALIDNDSIRLGLEANNWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            8043..8708
                     /locus_tag="VQU19_001032"
     CDS             8043..8708
                     /locus_tag="VQU19_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HET2480292.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAADPAGAARAFKDEIKR
                     IWG"
     gene            8712..9575
                     /locus_tag="VQU19_001033"
     CDS             8712..9575
                     /locus_tag="VQU19_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HET2480293.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFVEMSIDERDERL
                     ARLDWSKEERLEVVKEIYETGVRIPSICFSGHRRYPLGSKDPVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIN
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SRGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            9577..10281
                     /locus_tag="VQU19_001034"
     CDS             9577..10281
                     /locus_tag="VQU19_001034"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HET2480294.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVAWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            10460..12133
                     /locus_tag="VQU19_001035"
     CDS             10460..12133
                     /locus_tag="VQU19_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HET2480295.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALGDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVILQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVVQAFLEDI"
     gene            12245..13336
                     /gene="ulaG"
                     /locus_tag="VQU19_001036"
     CDS             12245..13336
                     /gene="ulaG"
                     /locus_tag="VQU19_001036"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HET2480296.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            13450..15426
                     /gene="tkt"
                     /locus_tag="VQU19_001037"
     CDS             13450..15426
                     /gene="tkt"
                     /locus_tag="VQU19_001037"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HET2480297.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVTDYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDANRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKVVRNLK"
     gene            15543..15842
                     /gene="yajC"
                     /locus_tag="VQU19_001038"
     CDS             15543..15842
                     /gene="yajC"
                     /locus_tag="VQU19_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HET2480298.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVEGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            15889..16317
                     /locus_tag="VQU19_001039"
     CDS             15889..16317
                     /locus_tag="VQU19_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HET2480299.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            16319..16729
                     /locus_tag="VQU19_001040"
     CDS             16319..16729
                     /locus_tag="VQU19_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480300.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            17029..19680
                     /gene="adhE"
                     /locus_tag="VQU19_001041"
                     /gene_synonym="adhC"
     CDS             17029..19680
                     /gene="adhE"
                     /locus_tag="VQU19_001041"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HET2480301.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITEPSMEATSALMNHEGIATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
     gene            complement(20665..20973)
                     /locus_tag="VQU19_001042"
     CDS             complement(20665..20973)
                     /locus_tag="VQU19_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET2480302.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
     gene            complement(20970..21278)
                     /locus_tag="VQU19_001043"
     CDS             complement(20970..21278)
                     /locus_tag="VQU19_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET2480303.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            complement(21283..22578)
                     /locus_tag="VQU19_001044"
     CDS             complement(21283..22578)
                     /locus_tag="VQU19_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET2480304.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTKFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPSAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGIVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            complement(22596..24005)
                     /locus_tag="VQU19_001045"
     CDS             complement(22596..24005)
                     /locus_tag="VQU19_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HET2480305.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLGLDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTEDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYGNIPWFISENGMGVENEARFIDENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSLCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            24163..24891
                     /locus_tag="VQU19_001046"
     CDS             24163..24891
                     /locus_tag="VQU19_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET2480306.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            25351..25545
                     /locus_tag="VQU19_001047"
     CDS             25351..25545
                     /locus_tag="VQU19_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2480307.1"
                     /translation="MKGKEYENRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDT
                     SSSDVTLITGKNGTGKSTLL"
     gene            complement(25911..27221)
                     /locus_tag="VQU19_001048"
     CDS             complement(25911..27221)
                     /locus_tag="VQU19_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HET2480308.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNFAITNGTLDVLAQHILYRTRTYPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYRKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTSIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            27458..28330
                     /locus_tag="VQU19_001049"
     CDS             27458..28330
                     /locus_tag="VQU19_001049"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HET2480309.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAILLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
BASE COUNT         8903 a         5055 c         5921 g         8529 t
ORIGIN      
        1 gtgcattggt tagttgttta ctttcttcat aaattttatt gtatcatatt tttgtttcac
       61 aggaagtcta ataaataaaa attctttaaa attttgttgg gaaaatggga aaagatataa
      121 atggaaactt agtataacac ttggaaaact ctgtaaaaat agtaagtcaa ttcatgtccc
      181 gttttttctc tagggaagtt gggcggctat atttatatga ccatttgtcg taataaacat
      241 ccctaccaag ggtcaataga aataaattca acgaaacttt tgctgtcaga tttagatgcc
      301 caatttgtca tttatactct ttcatatagg actttctata aggatggaaa aaagaaggga
      361 aatttgataa gataggaata tggattttga aaaaattgaa caagcttata cctatttact
      421 agagaatgtc caagtcatcc aaagtgattt ggcgaccaac ttttatgacg ccttggtgga
      481 gcaaaacagc atctatctgg atggtgaaac tgagctaaac caggtcaaag acaacaatca
      541 ggcccttaag cgtttagcac tacgcaaaga agaatggctc aagacctacc agtttctctt
      601 gatgaaggct gggcaaacag aacccttgca ggccaatcac cagtttacac cggatgctat
      661 tgctttgctt ttggtgttta ttgtggaaga gttgtttaaa gaggaggaaa ttactatcct
      721 cgaaatgggt tctgggatgg gaattctagg cgctactttc ttgatctcgc ttgataaaaa
      781 ggtggattac ttgggaatgg aagtggatga tttgctgatt gatctggcag ctagcatggc
      841 agatgtaatt ggtttgcagg ctggctttgt ccaaggagat gccgttcgtc cacaaatgct
      901 caaagaaagc gatgtggtca tcagtgactt gcctgttggc tattatcctg atgatgccgt
      961 tgcgtcgcgc catcaagttg cttctagcca agaacatact tacgcccatc acttgctcat
     1021 ggaacaaggg cttaagtacc tcaagtcaga cggatacgct atttttctag ctccgagtga
     1081 tttgttgacc agtcctcaaa gtgatttgtt aaaagaatgg ctgaaagaag aggcgagtct
     1141 ggttgctatg attagtctgc ctgaaaatct ctttgctaat gctaaacaat ctaagactat
     1201 ttttatccta cagaagaaaa gtgaaatagc agtggagcct tttgtttatc cacttgctag
     1261 cttgcaagat gcaagtgttt taatgaaatt taaagaaaat tttcaaaaat ggactcaagg
     1321 tactgaaata taaaatagat tttgttataa tagttgaaaa cgcttaaaaa ggggtatcat
     1381 gttatgacaa aaacaattgc aatcaatgca ggaagttcaa gtttgaaatg gcaattatac
     1441 ttaatgccag aggaaaaagt gttagccaaa ggtttgattg aacgtatcgg tttgaaagat
     1501 tcaatttcaa ctgtaaaatt tgacggccgt tctgaacaac aaattttgga tatcgaaaat
     1561 catacacaag ctgttaaaat tttattggat gacttgattc gtttcgatat tatcaaggct
     1621 tatgacgaga ttacaggtgt tggccaccgt gttgtagcag gtggagaata tttcaaagaa
     1681 tcaacagttg ttgagggaga tgttttagaa aaagttgaag agttgagttt gttggctcct
     1741 ctacacaacc cggccaatgc agcaggtgtt cgtgctttca aggaattgtt gccagacatt
     1801 accagtgtag ttgtttttga tacttccttc cacacaagta tgccagagaa agcttatcgc
     1861 taccctctac caacaaaata ttacacagaa aacaaggttc gtaaatacgg tgctcatggt
     1921 acaagtcacc agtttgtagc aggagaagct gcaaaactct tgggacgtcc attagaagac
     1981 ttgaagttaa ttacctgtca tattggtaac ggaggctcaa ttacagctgt gaaagccggc
     2041 aaatctgtag acacttctat ggggttcact cctcttggtg gtattatgat gggaacgcgt
     2101 acaggggata ttgatccagc tatcattcct tatttaatgc aatatacaga ggattttaac
     2161 acaccagaag atatcagtcg tgttcttaac cgtgaatcag gtcttttggg agtttctgct
     2221 aattctagcg atatgcgcga tatagaagca gctgtagcag aagggaatca cgaggctagc
     2281 ttggcttatg aaatgtatgt tgaccgtatc caaaaacata tcggtcagta ccttgcagtg
     2341 ctaaatggaa cagatgccat tgttttcaca gcaggtgtcg gtgaaaatgc agagaatttc
     2401 cgtcgtgatg taatctcagg gatttcgtgg tttggttgtg atgttgatga tgaaaagaat
     2461 gtctttggcg ttacaggaga catctcaaca gaggcagcta aaatccgtgt cttggttatt
     2521 ccaacagatg aagaattagt cattgcccgt gacgttgaac gcttgaaaaa ataagtgaaa
     2581 ctaaaaaaat attcaataca aggagttggg aaagttattt ttccagcttc tttttctgat
     2641 gaaattgtcc aaaaccttgc tatgattggc ttttttgaaa aatatggtat aatagtagta
     2701 atttaataga tggagttgag ttttgaagaa aaactttcgt gtaaaaagag agaaagattt
     2761 taaggcgatt ttcaaggagg ggacaagttt tgctaatcgc aaatttgtgg tctaccaatt
     2821 agaaaaccag aaaaaccatt ttcgagtagg tctatcagtt agcaaaaaac tggggaatgc
     2881 cgtcactaga aatcaaatta agcgacggat tcggcatatt atccagaatg caaaagggag
     2941 tctggtagaa gatgtcgact ttgttgtcat tgctcgaaaa ggagtcgaaa ccttgggata
     3001 cgcagagatg gagaaaaatc tactccatgt attaaaatta tcaaagattt accgggaagg
     3061 aaatgggagt gaaaaagaaa ctaaagttga ctagtttgct aggactgtct ctgttaatca
     3121 tgacagcctg tgcgactaat ggggtaacta gcgatattac agccgaatcg gctgattttt
     3181 ggagtaaatt ggtttacttc tttgcgaaaa tcattcgctt tttatcgttt gatattagta
     3241 tcggagtggg gattattctc tttacggtct tgattcgtac agtcctcttg ccagtctttc
     3301 aggtgcaaat ggtggcttct aggaaaatgc aggaagctca gccacgcatt aaggcgcttc
     3361 gagaacaata tccaggtcga gatatggaaa gcagaaccaa actagagcag gaaatgcgta
     3421 aagtatttaa agaaatgggt gtcagacagt cagattctct ttggccgatt ttgattcaga
     3481 tgccggttat tttggccttg ttccaagccc tatcaagagt tgacttttta aagacaggtc
     3541 atttcttatg gattaacctt ggtagtgtgg atacaaccct tgttcttccg attttagcag
     3601 cagtattcac ctttttaagt acttggttgt ccaacaaagc tttgtctgag cgaaatggcg
     3661 ctacgactgc gatgatgtat gggattccag tcttgatttt tatctttgca gtttatgcgc
     3721 caggtggagt cgccctatac tggacagtgt ctaatgctta tcaagtcttg caaacctatt
     3781 tcttgaataa tccattcaag attatcgcag agcgcgaggc cgtagtacag gcacaaaaag
     3841 atttggaaaa tagaaaaaga aaagccaaga aaaaggctca gaaaacgaaa taaataagga
     3901 ggaatctggt aatggtagta tttacaggtt caactgttga agaagcaatc cagaaaggat
     3961 tgaaagaatt agatattcca agaatgaagg ctcatatcaa agtcatttct agggagaaaa
     4021 aaggctttct tggtctattt ggtaaaaaac cagcccaagt ggatattgaa gcgattagtg
     4081 aaacgactgt tgtcaaagca aatcaacagg tagtaaaagg cgttccgaaa aaaatcaatg
     4141 atttgaacga gcctgtgaag acggttagtg aagaaaccgt tgaccttggt catgtggttg
     4201 atgctattaa aaaaatagag gaagaaggtc aaggtatttc tgatgaagtc aaggctgaaa
     4261 tcttaaaaca tgaaagacat gccagcacta tcttagaaga aactggtcac attgagattt
     4321 taaatgaact tcaaatcgag gaagcgatga gggaagaagc aggcgctgat gaccttgaaa
     4381 ctgagcaaga tcaaactgaa aatcaagact tgaaagagat gggcttgaag gtcgagcaaa
     4441 gttatgatat tgcccaggtg gctacggatg tgactgccta tgttcaagcg attgtggatg
     4501 acatggatgt tgaagctaca ctttcaaatg attataaccg tcgtagcatc aatctacaaa
     4561 ttgacaccaa cgaaccaggt cgtattatcg gctaccatgg taaagtcttg aaggccttgc
     4621 aactgttggc tcaaaattat ctttacaacc gctattccaa aaccttctac gttacaatca
     4681 atgtcaatga ttatgtcgaa caccgtgcag aagtcttgca gacctatgcg caaaaattgg
     4741 cgattcgtgt tttagaagaa ggacgtagtc atcaaacaga tccaatgtcg aatagtgaac
     4801 gcaagattat ccaccgtatt atttcacgta tggatggcgt gaccagttac tctgaaggtg
     4861 atgagccaaa tcgctatgtc gttgtagata cagaataagt aaaatcaggg ttgacctgat
     4921 tttttgctag ctagaggagg ttaaactaat gttgaataag ataagagact atttagactt
     4981 tgctggtttg cagtaccgta atcctgataa agcgggagca gagcgagaga agatgctggc
     5041 attccgccac aaaggacaag aggcccgaaa ggcttttaca gaactggcca aagcctttca
     5101 agcaagccat ccaggatggc aactccaaca gactagtcag tggatgaatc aggcccagcg
     5161 tttgagacca catttttggg tttatctaca gagagacgaa caagtgacag aacctatgat
     5221 ggccttacgt ttgtatggga catctactga ctttggaatt tctttggaag tcagtttcat
     5281 cgaacgtaag aaggatgagc aaacactggg caagcaggcc aaagttttag acattccaac
     5341 cgttaaaggg atttattatc taacctactc taatggtcaa agtcaacggt gggaggcgaa
     5401 tgaagaaaag cgtcgtactt tacgcgagaa ggtgagaagt caagaagttc gaaaagtttt
     5461 agtgaaggta gatgttccta tgacagaaaa ttcgtctgaa gaagaaatcg tagaaggctt
     5521 attgaagtct tattctaaaa ttcttcccta ttatctagct acgagaaaat aagataattt
     5581 gtaaaacatc ataaatcata cagtccaaga gtgaacagtc cgctgtgtaa ttcttggtct
     5641 ttttgtttgc gctttcgcat tatataataa acttacaaaa acaattcaaa aggagaacaa
     5701 ttatggaagt cgtttcaagt gttctaaatt ggttttctag caatattttg cagaatcccg
     5761 catttttcgt aggtttattg gtgttgatag gatatgcact tttgaaaaaa cctgcccatg
     5821 acgttttttc agggtttgtt aaagcaacag tagggtatat gttgcttaac gtgggtgctg
     5881 gtggtttggt tacaaccttt cgtccaatct tagcagctct taactacaaa ttccaaattg
     5941 gtgcagcggt tatcgaccct tactttggac ttgctgcagc aaacaacaaa attgcagcag
     6001 agtttccaga ttttgttgga actgcaacta cagctctatt gattggtttt ggaataaata
     6061 tcttgctcgt agctcttcga aagattacga aggtaagaac cctctttatt actggtcaca
     6121 tcatggtaca acaagctgca acagtatctc ttatggttct attcttagta ccacaattgc
     6181 gcaatgctta cggtacagca gcgattggta tcatctgtgg actttactgg gcagttagtt
     6241 caaatatgac tgttgaggca actcaacgct tgactggtgg tggcggattt gcgattggtc
     6301 accaacagca atttgcaatc tggtttgtag ataaagtagc aggacgcttt ggtaagaaag
     6361 aagaaagttt agacaatctt aaattaccta agttcctctc aatcttccac gatacagttg
     6421 ttgcatctgc taccttgatg ctcgtattct tcggagccat tcttttaatc ttgggtccag
     6481 acattatgtc taataaagaa gtcatcactt caggaactct attcaatcct gctaaacaag
     6541 atttctttat gtacattatc caaacagcct ttaccttctc agtttacttg ttcgttttga
     6601 tgcaaggtgt ccgaatgttc gtatctgagt tgacaaacgc cttccaaggt atttcaaaca
     6661 aattgttgcc aggttcattc ccagcggttg acgttgcagc ttcttatgga tttggttctc
     6721 caaatgctgt cttgtcagga tttacctttg gtttgattgg tcaattgatt acaattgttt
     6781 tgctcatcgt ctttaaaaat ccgattctta ttattacagg atttgtacca gtgttctttg
     6841 acaatgcagc cattgcggtc tacgctgata aacgcggcgg atggaaagcg gctgttatcc
     6901 tttcctttat atcaggtgtc cttcaagttg ctctaggagc tctttgtgtg gcccttctcg
     6961 atttggcatc ttatggtggc taccatggaa atatcgactt tgaattccca tggcttggat
     7021 ttggatatat cttcaaatac cttggtattg ttggttatgt acttgtgtgt ctcttcttgc
     7081 ttgttattcc tcaacttcaa tttgccaaag caaaagataa agagaaatat tacaacggtg
     7141 aagttcaaga agaagcttag tatctagaaa aggagaaata aaatggttaa agtattagca
     7201 gcgtgcggaa atggaatggg ttcatcaatg gttatcaaga tgaaggttga aaatgctctc
     7261 cgtaagctta atcaaacaga ttttacagtc aattcatgca gtgtcggtga agctaaaggt
     7321 ttagcagtag gatatgacat tgtaatcgct tctcttcatt tgattcaaga attggaaggg
     7381 cgaactaatg ggaagttaat tgggcttgat aacttgatgg atgataaaga aatcaccgaa
     7441 aaactcagtc aagcactaca gtaaaaggtt ggagggggct ggacagaaac tgagagttat
     7501 cgtttctgtc cagccccctc tttaaataaa ggaggcagat atgaatttaa aacaagcttt
     7561 aattgacaat gactcgatcc gactaggttt agaggctaac aattggaaag aagcagtcaa
     7621 ggtagcagta gatcccttga ttgaaagtgg ggcaattttg ccagagtatt acgatgctat
     7681 cattgaatcg actgaagagt atgggcctta ctatatcttg atgccaggta tggctatgcc
     7741 ccacgctaga cctgaagctg gtgtgcaaag tgatgccttt tcattgatta ccttacaaaa
     7801 tcctgttgta ttttcagatg ggaaagaggt atctgttttg ttggcactag cagcaacaag
     7861 ttcaaaaatt cacacaagtg tagccattcc acaaattatt gccctgtttg aattagaaga
     7921 ttctattgca cgtttacagg cttgccagac taaagaagat gtcttggcta tgattgaaga
     7981 atctaaggat agcccttatc tcgaaggatt ggatttggaa agttagaaag aggaataaag
     8041 aaatgacaaa aagaatacct aatttacaag ttgcattaga ccattcagac ttgcaaggag
     8101 cgattaaagc agctgtttct gttggtcagg aagtagatat tatcgaagct ggaactgttt
     8161 gcttgcttca agttggaagt gaactggctg aagtcttgcg tagccttttc ccagataaga
     8221 ttattgtggc agacacaaaa tgtgctgatg ctggtggaac agttgctaaa aataatgcgg
     8281 ttcgtggagc agactggatg acttgtatct gttgtgcaac catccctact atggaagcag
     8341 ctctaaaggc tatcaagact gaacgaggag aacgaggcga aatccagatc gagctttatg
     8401 gcgattggac ttttgaacaa gctcagcttt ggctagatgc aggtatctca caagctattt
     8461 atcaccaatc tcgtgatgct cttcttgctg gtgaaacttg gggtgaaaaa gaccttaata
     8521 aggttaaaaa actcattgac atgggcttcc gtgtatctgt aacaggtggt ctagatgtag
     8581 atactctcaa actctttgaa ggtgttgatg tctttacctt tatcgcaggt cgtggaatta
     8641 cagaggctgc ggatccagca ggagcagcgc gtgccttcaa ggatgaaatc aaacgaattt
     8701 gggggtaaat catggtacgt ccaattggaa tttatgaaaa ggcaacccca acacacttta
     8761 cttggctaga acgtttaaat tttgccaagg agttaggctt tgattttgtc gagatgtcta
     8821 ttgacgaacg tgacgagcgt ttagcaagac ttgactggag taaggaagaa cgcttggaag
     8881 ttgtcaaaga aatctatgaa actggtgttc gtattccttc tatctgtttt tcaggccatc
     8941 gtcgctaccc attgggttca aaagatccag ttctagagga aaaatctcta gaactcatga
     9001 aaaaatgtat cgaattagct caagacttgg gagttcgtac gattcaatta gctggttacg
     9061 atgtttacta tgaggaaaag tcaccccaga cacgccaacg ttttatcaaa aatttgagaa
     9121 aagcctgtga ctgggctgaa gaagctcagg tggtacttgc tattgaaatt atggatgatc
     9181 ctttcatcaa tagcatcgaa aaatatttgg ctatagaaaa agagattgac tctcccttcc
     9241 tctttgtata tccagatatt ggtaatgtgt ctgcatggca taatgatatc tatagtgagt
     9301 tttatcttgg tcatcatgcc atcgcagctc tccatctcaa ggatacttat gcagtgacag
     9361 aaagttcaag gggccagttc cgagatgtac cttttgggca aggttgtgtc aaatgggaag
     9421 aagctttcga tattttaaag gaaaccaatt ataatggacc tttcctaatc gaaatgtggt
     9481 ctgaaaattg tgaaacagta gaagaaacac gcgcagccat tcaagaggcg caagcttttc
     9541 tctatccact cattaagaaa gcaggtttga tgtaagatga atcaagtaat caatgctatg
     9601 cgtaaacgag tctgtgatgc caatcaatca ttgccaaaac atggacttgt caaatttacc
     9661 tgggggaatg tatctgaagt caatcgcgaa ctcggtgtca ttgttatcaa accatcaggc
     9721 gtggattatg acgaattgac acctgaaaac atggtagtga ctgatctaga tggtaagatc
     9781 ctagaagggg atttaagacc atcttccgac ctcccaactc atgtgcaatt atataaggct
     9841 tggtcagaaa ttggtagtgt ggttcacacc cattcgacag aagctgttgc ttgggctcag
     9901 gcaggtcgtg atattccttt ctacggaaca acccatgcag attatttcta cggttcaatc
     9961 ccttgcgccc gtagtttgac caaggacgaa gtagaagtgg cctatgaaaa agatactggc
    10021 ctggttatcg tagaagagtt tgaacatcgc ggacttaacc cggttgaagt accaggaatt
    10081 gttgtacgca atcacggtcc attcacctgg ggcaaaaatc cagagaatgc tgtttatcac
    10141 tctgtcgtac tagaggaagt atcaaagatg aatcgcttta cagaacaaat caatccaaga
    10201 gttggacctg ctccccagta catactagaa aaacactacc aacgtaaaca tggaccaaat
    10261 gcttattatg gtcaaaagta agaacgatga aggaggagaa aaagataaat ttagctcctc
    10321 tttttacatt tgatttttat tgagagtaaa gttggagttg aagtaatttt aaaagatttt
    10381 ttagaaatag cgcttgatat atatatggta aaataaaaag aattgctgtg atatcaatag
    10441 atttggggga ttttttaata tggtactgga taaggcaagt tgtgatttgc ttcaatattt
    10501 gatggatcaa gaaacgtcca aaacgattat ggcgatttcg aaagatttga aagagtcaag
    10561 aaggaaaatt tattatcaca ttgacaaaat caatgctgct ctgggtgacg aggcgcttca
    10621 catcattagt attccacgaa ttggtattca cttaacggaa gagcagagag atgcttgttg
    10681 taaactatta tcggaagtag attcgtacga ttatatcatg agtgcgcatg aacgtatgat
    10741 gataatgtta ctatggatag gtatttctaa agaacgtatt acgattgaaa aattgataga
    10801 gttaacagag gtatctagga atactgttct caatgatttg aatagtattc gttatcaact
    10861 aactttggaa caatatcagg tgatcttgca agtgagcaag tcacagggat accaccttca
    10921 tgcccaccct cttaataaaa ttcagtatct tcaatcgctt ctatatcata tttttatgga
    10981 agaaaatgcc acttttgtat ctattttaga agataagatg aaagagaggt tagatgatga
    11041 gtgtttgctt tctgttgaaa tgaaccaatt ttttaaggaa caggttcctt tagttgaaca
    11101 agatttaggg aagaaaataa accatcatga aataactttt atgttgcagg ttctacctta
    11161 tttgctgtta agctgtcata atgttgaaca gtatcaagaa agacatcagg atatagagaa
    11221 agaattttct ttgataagaa aaagaataga gtatcaggtg tctaagaaat taggagaacg
    11281 gttgtttcaa aagtttgaaa tttctttgtc aggacttgaa gtttctcttg tagctgttct
    11341 cctcctctcc tatcgtaaag atttggatat tcatgcagaa agtgatgatt ttcggcaatt
    11401 aaaacttgct ttagaagaat ttatctggta ttttgaatca caaatccgaa tggagattga
    11461 gaacaaggat gatttgttac gaaatttgat gatccactgt aaagccttgt tatttagaaa
    11521 gacttacggt attttttcta aaaatcctct aacaaaacaa attcgatcca agtatggaga
    11581 attattttta gtcactagaa aatctgcgga aattttagaa ggagcatggt ttattcggct
    11641 aacagacgat gatattgcct atttgacgat tcatattgga ggatttttaa aatatacacc
    11701 atcatctcaa aaaaatatga aaaaagttta tctcgtttgt gatgaaggtg ttgcggtttc
    11761 gagacttttg ctgaaacaat gcaaacttta ttttccaaat gagcaaattg acactgtatt
    11821 tacaacagaa caatttaaga gtgtggaaga tattgcacaa gttgatgtag tgattactac
    11881 taatgatgat ttggatagca gatttccgat tttaagggtt aatcctatcc ttgaagcaga
    11941 agatattttg aaaatgctag actatcttaa acacaatata tttcgtaata agagcaaaag
    12001 tttcagtgaa aatctttcta gtcttatttc gtcttatatt gtagacagca agttggctag
    12061 taagttccaa gaagaggttc aaacacttat aaatcaagaa atagtagttc aagctttttt
    12121 ggaagatatt tgaaggacag tccaatgatg aacacaaacc tgtgtttttc ttggtctttt
    12181 ttagtgtttt gaagggtggt atactaatct caaagataac aattatatcc aaaggaggca
    12241 acatatgcca aacgtcaaag aaattacaag agagtcatgg attttagcca ctttcccaga
    12301 gtggggaaca tggttgaacg aagaaatcga agaagaagtc gtacctgaag gcaactttgc
    12361 catgtggtgg ctaggcaact gtggtacttg gattaagaca ccagctggtg ctaacgttgt
    12421 catggacctt tggtcaaacc gtggaaaatc aaccaaaaaa gtgaaagata tggttcgtgg
    12481 gcaccaaatg gcaaatatgg caggtgttcg taagctgcaa ccaaacttgc gtgttcagcc
    12541 aatggttatc gatccatttg ctatcaacga actagactat tacttagttt cacacttcca
    12601 cagtgatcat atcgacccat acacagctgc agcaattctc aataatccta agttagagca
    12661 tgttaagttt atcggtcctt accactgtgg acgaatctgg gaaggatggg gtgttccaaa
    12721 agaacgtatc atcgttgtta aaccaggtga cactatcgaa ttaaaagata tgaagattca
    12781 tgcagtagaa tcatttgacc gtacttgctt ggtaactctc ccagtgaacg gtgctgatga
    12841 gacaggcggt gaacttgctg gcttggctgt tacagatgaa gaaatggctc aaaaggctgt
    12901 taactatatc tttgaaacac caggtggaac catctatcat ggtgcagatt ctcacttctc
    12961 aaactatttt gcaaaacatg gtaaagactt taaaattgat gttgctttga ataactatgg
    13021 tgaaaatccg gtaggtatcc aagacaaaat gacatctatc gaccttcttc gtatggcaga
    13081 aaatctgcgt accaaagtca ttatcccagt tcactatgat atctggtcta acttcatggc
    13141 ttctactaat gagattctag aactttggaa aatgcgaaaa gatcgcttgc aatacgattt
    13201 ccatccattt atctgggaag ttggcggtaa gtacacttat cctcaagatc aacacttagt
    13261 agaataccat catccacgtg gttttgatga ttgttttgaa caagactcta acattcaatt
    13321 taaagctttg ctataatata aaaatattct ttggaggtta tccgtatgtt gcatgatacg
    13381 gataattttc atataatagt aaaatagaat gtgtgattca ataatcacct caaatagaaa
    13441 ggaaattcta tgtcaaatct atctgttaat gcaattcgtt ttctaggtat tgacgccatt
    13501 aataaagcca actcaggtca tccaggtgtg gttatgggag cggctccgat ggcttacagc
    13561 ctctttacaa aacaacttca tatcaatcca gctcaaccaa actggattaa ccgcgaccgc
    13621 tttattcttt cagcaggtca tggttcaatg ctcctttatg ctcttcttca cctttctggt
    13681 tttgaagatg tcagcatgga tgagattaag agtttccgtc aatggggttc aaaaacacca
    13741 ggtcacccag aatttggtca tacggcaggg attgatgcta cgacaggtcc tctagggcaa
    13801 gggatttcaa ctgctactgg ttttgcccaa gcagaacgtt tcttggcagc caaatataac
    13861 cgtgaaggtt acaatatctt tgaccactat acttacgtta tctgtggaga cggagacttg
    13921 atggaaggtg tctcaagcga ggcagcttca tacgcaggct tgcaaaaact tgataagttg
    13981 gttgttcttt atgattcaaa tgatatcaac ttggatggtg agacaaagga ttcctttaca
    14041 gaaagtgttc gtgaccgtta caatgcctac ggttggcata ctgccttggt tgaaaatgga
    14101 acagacttgg aagccatcca tgctgctatc gaaacagcaa aagcttcagg caagccatct
    14161 ttgattgaag tgaagacggt tattggatac ggttctccaa acaaacaagg aactaatgct
    14221 gtacacggcg cccctcttgg agcagatgaa actgcatcaa ctcgtcaagc cctcggttgg
    14281 gactacgaac catttgaaat tccagaacaa gtatatgctg atttcaaaga acatgttgca
    14341 gaccgtggcg catcagctta tcaagcttgg actaaattag ttacagatta taaagaagct
    14401 catccagaac tggctgcaga agtagaagcc atcatcgacg gacgtgatcc agtcgaagtg
    14461 actccagcag acttcccagc tttagaaaat ggtttttctc aagcaactcg taattcaagt
    14521 caagatgcct tgaatgttgt ggcagctaaa ttaccaacct ttctaggtgg atcagctgac
    14581 cttgctcact caaacatgac ttatatcaag acggatggac ttcaagacga tgccaatcgc
    14641 ttgaatcgta acattcagtt tggtgttcgt gaatttgcaa tgggaacaat cttgaacggg
    14701 atggcccttc atggtggact tcgtgtatac ggtggaactt tcttcgtctt ctctgactat
    14761 gtgaaggcag ctgtccgctt gtcagcctta caaggacttc ctgtgactta tgtctttacc
    14821 catgattcaa tcgcagttgg ggaagatggt ccgactcatg aaccagttga gcatttagca
    14881 ggtcttcgtg ctatgccaaa tctaaatgtt ttccgtccag cagatgcgcg tgaaacgcaa
    14941 gcagcttggt accttgcagt gacaagtgag aaaacaccaa ctgcccttgt cttgacacgt
    15001 caaaatttga ctgttgaaga tggaacagac ttcgacaagg ttgctaaagg tgcttatgtt
    15061 gtatatgaaa atgcagccga ctttgatacc atcttgattg cgacaggttc agaggttaat
    15121 cttgctgtct cagctgctaa agaattggct agtcaaggcg aaaaaatccg cgtagtcagc
    15181 atgccatcta cagatgtctt tgataaacaa gatgcagctt acaaggaaga aattcttcca
    15241 aatgcagtcc gccgtcgtgt tgcagtcgaa atgggtgcaa gtcaaaactg gtacaaatat
    15301 gttggtctcg atggtgccgt tctaggtatt gataccttcg gagcctctgc cccagcacca
    15361 aaagtattgg cagaatatgg ctttactgta gaaaatcttg taaaagttgt tcgaaacttg
    15421 aaataatcct aaaaatcagg gcgtaagctc tggtttttct taccagaaaa gtaaggtaca
    15481 atcttgtaaa agtagctgaa atttgatata gtagtcctat gtaaaagaca aaggagaaaa
    15541 caatgaatcc aaatattact tttttaatca tgcttgtagg tatgatggcc ttgatgttct
    15601 ttatgcaacg ttctcaaaag aaacaagctc aaaagcgtat ggaaagctta aataaactac
    15661 aaaaaggcta tgaagtgatt acaatcggtg gactttatgg aacagtcgat gaagtagata
    15721 cggagaaggg aacaatagtt cttgacgtag agggagttta cttgactttt gaactagctg
    15781 ctatcaagac agtattaccg ctgaaagaaa cagcttcact agaaggcgca attgaaaaat
    15841 aagacgggat cacgaactcc cgtttttcta taaaagaaag gaaatgggat gaaaaaatta
    15901 gtctttgtct gtctgggaaa tatttgccgt agccctatgg ccgagtttgt tatgaaatca
    15961 atgacagata actacgaaat ccaaagtcga gcaacttcct cttgggaaca tggcaatccg
    16021 attcataagg ggactcaggg aatttttcaa gagtatgaga ttccttatga caagaacaag
    16081 acatcgcttc agattagtaa ggaagatttt gaagcctttg attatattat cggaatggac
    16141 gcttcaaata tttctgactt acgtcagatg tgtccagtag actgtcaaga taagatttac
    16201 tcattttcat ctgaaagtgt tccagaccct tggtatacag gagattttga agaaacctat
    16261 cgacgtgttc aagagggctg tcaagcttgg ttagaacgtt tagaaaagga gagttaaggt
    16321 ggaaaatctt acgaattttt acgaaaagta tcgtgtctat ctgactcgtc cacgtttaga
    16381 gcttttggca gtagttacca ttgttttctg tgctgtactc gtcttttttc taaatattcc
    16441 aggaaaaggt gtcttaaaac tcgataatgg aacgattgtt tatgatggca gtcttgtccg
    16501 cggtaaaatg aatggccaag gtaccattac cttccaaaat ggagaccaat atacaggtgg
    16561 cttcaacaat ggagccttca acggaaaagg tacctttcaa tctaaagaag gctggaccta
    16621 cgaaggtgat tttgtaaatg gtcaggctga aggaaaaggg aaactaacaa cagaacaaga
    16681 agtcgtttat gaaggaactt ttaaacaagg cgtttttcaa caaaaataaa gcctccttat
    16741 caaaggaggt attattagaa tcgcaaggta agcgcttacc tgcaaatccc tttctttcca
    16801 aatccctctt ccaagcaagt ttgtgaaata aaaaatattt gaaataaatt tcacaaactt
    16861 caaagataaa acctgataag aaaagaaaat gagaaaagtt tcacaagagt ttaaaaattc
    16921 tttgtgaaat gtttatgaaa ctgtttacaa agttgaaata atgcgttata ataaacttgt
    16981 gaaaaaatta acaaaggata tcgttccttg aaagctatgg aggaaaatat ggctgataaa
    17041 aaaactgtga caccagagga aaagaaactc gttgctgaaa aacacgtaga tgagttggtt
    17101 caaaaagctc tagttgccct tgaagaaatg cgtaaattgg atcaagaaca agttgactac
    17161 atcgttgcca aagcatcagt agcagctttg gatgcccacg gagaattggc tttacatgcc
    17221 tttgaagaaa caggacgtgg tgtatttgaa gataaagcaa ctaagaactt gtttgcttgt
    17281 gaacacgtgg taaacaacat gcgtcacact aaaacagttg gcgttatcga agaagatgat
    17341 gtaacaggat tgaccctgat tgctgaacca gttggtgttg tttgtggtat cactccaaca
    17401 acaaacccaa catcaacagc gatcttcaaa tcattgattt cattgaagac acgtaatcca
    17461 atcgtctttg ccttccatcc atcagctcaa gaatcatcag ctcatgcagc tcgtatcgtc
    17521 cgcgatgcag ctatcgcagc tggtgctcct gaaaactgtg tacagtggat cactgaacca
    17581 tctatggaag caactagtgc ccttatgaac cacgaaggta ttgcaacaat ccttgcaaca
    17641 ggtggtaatg ccatggttaa agccgcatac tcatgtggta aaccagctct tggggtaggt
    17701 gccggaaacg ttccagctta tgttgaaaaa tcagcaaaca ttcgtcaagc agcacacgat
    17761 atcgtcatgt ctaaatcatt tgataacggt atggtctgtg catctgaaca agcagttatc
    17821 attgataaag aaatttacga tgaatttgta gcagagttca aatcttacca cacttacttt
    17881 gtaaacaaaa aagaaaaagc tcttcttgaa gagttctgct tcggcgtcaa agcaaacagc
    17941 aaaaactgtg ctggtgcaaa attgaacgct gacatcgttg gtaaaccagc aacttggatt
    18001 gcagaacaag caggatttac agttccagaa ggaacaaaca ttcttgctgc agaatgtaaa
    18061 gaagttggcg aaaatgagcc attgactcgt gaaaaattgt caccagttat tgcagttttg
    18121 aaatctgaaa gccgtgaaga tggtattact aaggctcgtc aaatggttga atttaacggt
    18181 cttggacact cagcagctat ccacacagct gacgaagaat tgactaaaga atttggtaaa
    18241 gctgttaaag ctattcgtgt tatctgtaac tcaccttcta cttttggtgg tatcggggac
    18301 gtttacaatg ccttcttgcc atcattgaca cttggatgtg gttcttacgg acgcaactca
    18361 gttggggata acgttagtgc cattaacctc ttgaatatca aaaaagtcgg aagacggaga
    18421 aataacatgc aatggatgaa acttccttca aaaacatact ttgaacgtga ttcaattcaa
    18481 taccttcaaa aatgtcgtga cgttgaacgt gtcatgatcg ttactgacca tgccatggta
    18541 gagcttggtt tccttgatcg tatcatcgaa caactggacc ttcgtcgcaa taaggttgtt
    18601 taccaaatct ttgcggatgt agaaccggat ccagatatca caactgtaaa ccgtggtact
    18661 gagattatgc gtgccttcaa accagatacc atcatcgcac tcggtggtgg gtctccaatg
    18721 gatgctgcca aagtaatgtg gctcttctac gagcaaccag aagtggactt ccgtgacctt
    18781 gtccaaaaat tcatggatat ccgtaaacgt gccttcaagt tcccattgct tggtaagaag
    18841 actaaattca tcgcgattcc aactacatct ggtacaggat ctgaagtaac accatttgcc
    18901 gttatctctg ataaagcaaa caaccgtaaa tacccaatcg ctgactactc attgacacca
    18961 actgtggcaa tcgtagatcc tgctttggta ttgacagttc caggatttgt tgctgctgat
    19021 actggtatgg acgtattgac tcacgcgaca gaagcatacg tatcacaaat ggctagtgac
    19081 tacactgatg gtttagcact tcaagccatt aaattggtct ttgaaaatct cgaaagctca
    19141 gttaagaatg cagacttcca ctcacgtgag aaaatgcata acgcttcaac aatcgctggt
    19201 atggcctttg ccaatgcctt cctaggtatt tctcactcaa tggcccataa gattggtgcg
    19261 caattccaca caatccacgg tcgtacaaat gctatcttgc ttccatacgt tatccgttac
    19321 aacggtacac gtccagctaa gacagcaaca tggcctaagt acaactacta ccgtgcagat
    19381 gaaaaatacc aagatatcgc acgcatgctt ggacttccag cttctactcc agaagaaggg
    19441 gttgaatctt acgcaaaagc tgtctacgaa ctcggtgaac gtattgggat ccaaatgaat
    19501 tttagagacc aaggaattga cgaaaaagaa tggaaagaac attctcgtga attagccttc
    19561 ctggcttatg aagaccaatg ttcaccagct aacccacgtc ttccaatggt agaccatatg
    19621 caagaaatca tcgaagatgc atactatggc tacaaagaaa gaccaggacg ccgtaaataa
    19681 ttgtttatca gtctagaagc aagacaaaaa ctcaatttga gggaaagatc cagtaatttt
    19741 tctatgataa aaggcatcct atcaaggttt ttgaacacct gataggatgc ctttttatga
    19801 tattgaggcc tttttgccct ttttgaaaaa ctagaataga aacaaaatat ataatagatt
    19861 gaaactggaa tagtacactt ctgcttctaa aacattgtta gaattcgatt tgactgtcct
    19921 gatcgatttg tcctattcct atttcatttt actatataaa aaatatagta tagtagactg
    19981 aatctaaaat agtacgaaac aattgctaaa acatttatag aaattaattt tactttcctg
    20041 atagagttgt tcacatctta tttcaattca ctatagttta atttaagagt agtatttact
    20101 aaggcccaat taaaatcaaa gagcaaacta gaaaacgagt gccattcagc tcaaaacact
    20161 gatttgagat tgcagataag actagcccct cattaacagg tttacgataa aacgatgaca
    20221 aggtgtgttg ctttttgatt tctaaagagt ataatgatag atctctataa aataagtgcg
    20281 aaggaaatga gcttttatag tcctttcgtt ttaaaatact atctcagatg ttcttatatc
    20341 gacaagaagt ttttgagtca ttccctcatc atacatatta aataaatagt ggctcattca
    20401 attttttact agaataataa gctagtatag taaactgaaa taagatataa acaaataaat
    20461 tggagcttaa catctatttc cagcaatttt ttagaaactg cagtggacta ttctaaattc
    20521 aacacattat aaaaactaga gtaaaagaaa aggattggat cttgtgtaat gcaggatcta
    20581 atcctttcaa tcattttgtc caacttttgg aggttcctac aatgtagccg tcattaataa
    20641 agacagatgg gaacgacagt gttcctattt attttgatag agatcgatga attctttaga
    20701 tagcaactga ataatctctg ttgaagccat ttggtcttct gcatgcataa atagcaagga
    20761 gaatcctatt ttttctccag tagcttcttt ttgtatgaga ttagagtgaa tcttgtgcgc
    20821 ttctactaag gagtcttccg cttcttcaac tttaattttc gcttctttta aatttcctgc
    20881 cttagctagt tggatggctt caataaagga tgatttggct gctccactat tggcaatgag
    20941 ctgaaaacag atatattcca tttcttctgt catcttattt ctcctatcca tgcaagtgct
    21001 tgttccagaa cttttgctcc attcatcatt ccgtaatccc gcatatcaat ggtatctaca
    21061 gggatatttc ctgcaatttc tttcacagca agtaactcat aacgaatttg tggcccaatt
    21121 agaatgacat ctgcttcatg gatattcttt ttcgcttctg tcattgattt tgcttggata
    21181 gaaatttcaa tcccacgttc agtcgcactt tgttgcattt ttttaacaag catacttgtc
    21241 gacattcccg cattacatac taataaaatt tgtttcataa tcttaacctt ccatttcttg
    21301 ctcaacaact ttgtcattaa ctttgataaa tggaatgtat agaagaactc caagtgcaaa
    21361 gatgatgaat tgaactagaa ctgctctcac gtcccctgct gttgctaacc atgcatttaa
    21421 gaatactggt gtagtccaag gaacttgtat aaatgcagga ctcatgaatc ctgtaactgt
    21481 tgctaagtag ctgattaaaa taccaaggac tggaactgtg ataaatggaa tagctaatga
    21541 aatgttataa acgattgggt aaccgaataa tactggttca ttgatattga agataccagg
    21601 tccaaaagat aatttagcca cgtttttaga aacagcattg cgactcacta agaatgttgc
    21661 tattaataaa cataatgtag atccactacc acccattaaa gcgaatgttt gtatttgtga
    21721 taagttgatg atgtgtggaa tggcttgtcc attatttgct gcagtgatgt tttcagtaat
    21781 gttaattaat agtaatggtt ctaggatggc actgtaaata actgcttggt gaataccaaa
    21841 tagccataac atatttccta aagagtaaat aataatgacc ccgattaagc ttgtaccaat
    21901 atgacgaatt ggttcttgaa taaagattgt aatgattgag attaagttca ttccagttat
    21961 attgaataat aatgctgaaa caatcccaaa taaggagatg acagtcatga ctggaagtaa
    22021 tacgctaaat gatctactaa cagctggtgg aatattttca ccaaggttca tttgtaaagc
    22081 tttaacgttt gataattcaa tgaataattc tgttgcaata atcgctacga taaccccggc
    22141 gaacattgcg cctgtacctg tgttgttgaa tgaaagaaca cctgaaatgt ttacagcatc
    22201 ttttgctccg tcaggaacta cagaaactgt atttggcatc atcacaatta aagaaactaa
    22261 tgatagcatt gatgctgctg acgggttttc gaaatctctg tttttagcta agaaataacc
    22321 aaccattaca gcaataatca tacctgaaat acttaaagta ccgtttgcaa ttgttattcc
    22381 ccaatattgg aattttgtta atgtatcccc ttggaaaatc cacttaaata ccgtgttgtt
    22441 caaaagaacg attaaacctg ccaaaatata taatggcatt actgttacga atgcatctct
    22501 tagggttttt aaatgaattt ggttccctag tttaccagca aaggtggcaa attgatctat
    22561 aaattttgag tttttcatct gaatatctcc tctctttact cctcaatttc tacttcaaaa
    22621 ccgttattgt cacttacttt gcgataccat cttcctgagc tcttgatggt tctcttttgc
    22681 gtttctaaat caacggagat aaatccgtaa cgattcttat atgcattatt ccaagaccag
    22741 caatcaaatg cggtccaagc gtggtatcca aaacagagac ttccctcttc aatggcttta
    22801 tgtagccatc ttaaatgttc ttcataaaat tcaatacgat acacgtcatc gataactcca
    22861 ttttcatcga taaaccgtgc ttcgttttca acacccattc cgttctcact gataaaccat
    22921 gggatattac catattcttc cttcacaatc atagcaatat cataaatggc tttcggaaaa
    22981 atttcccaac cacgatatgg attcatgcga cgctccggcc attcatactc tttgaagtat
    23041 tggtctggca tccagggcgt ctgatattcc tcaggatttg cttgtgcttg aacacgtttt
    23101 ggatggtagt agtttactcc aagaaaatca accgtatttg atttcatcag ttgaagctct
    23161 ttttcggtat gactccataa cacgccatct ctctctagct gttttaccaa tctttctggg
    23221 aaagttcctt taacagctgg attcaagaag actttgttaa agaagtcttc tgtaaatcga
    23281 cttgcttcta agtcttctgg agaattactt cttggataag caggtgtcaa gtttaaaata
    23341 atcccaatct ttccatcaag tcctaatgag cgatatagtt gaatcacttt tgcactagca
    23401 aggtttagat tatagatgac ttgtacggcc tcttttccct ttccttttag atttggataa
    23461 tggaaagcat ataagtatcc tgcttctgga atgaccattg gctcattgaa agttgtccag
    23521 taatgaacct tatctccaaa gcatgtgaaa gcagtcttgg caaacttcac gaataactcc
    23581 actacatgtt tgctttccca accaccgtat ttttgaagaa gttccactgg taaatcaaaa
    23641 tgatgtaaat tcatcacaag atccatctgg ttctttttag cttcttcaat gatggcattg
    23701 tagaaagcaa taccttttgg atcaggctca cctgtctcta aattcttgat gagtcgactc
    23761 cattggatgg aagtgcggaa agaattaact ccaatttcct tcatcaagtg gaaatcttcg
    23821 gtgtaagtat gaaaaaagtt actggctaca agaggtccga cattatcgaa aaaatcttct
    23881 ggatgcgttt tgaaccagta gtccatcaca ttttcatgta cttttccata ttgaccttct
    23941 gtctgaggtc cgctagaagc agctccccac caaaacagat taggaaatac taactttttt
    24001 ttcatgctca acctcctttc tattatgcta tacataaagt atagcataat tttaaaattt
    24061 gtctagacat ttttaaaaat tgttgataca tatattgtgt ttgcctcatt tcttgaactt
    24121 tgttatacta ctattagaat attatagaga gaaccagatt aaatgagtac aaaatattta
    24181 tttatttaca atgagattcg tgaaaagatt ctctgtaata aatataccat gaacgaacaa
    24241 ttgcctgatg aaatgacatt agctaaacag tttgcctgta gtcgaatgac gatcaaaaaa
    24301 gctttagact tgttagtttc tgagggctta atttttagaa aacgtgggca gggaaccttt
    24361 gttctctctc gtggcagctc aaaaagaaaa ttaatcgttc cagaaagaga tatccgggga
    24421 ctgacaaaaa tatctgaaga tgctcattct acaattgact cgaggattat tcacttcaaa
    24481 ttagaatttg caaatgaatt tttagcagaa aaactacagg tcgctttgca gagtccagtt
    24541 tataatattt accgcctgcg tattattgac ggtaaacctt atgttctgga acaaacttat
    24601 atgagtaccg atgttattcc aggtattact gaagatattt tacaaaaatc gatttacaat
    24661 tacattgaag gaaagttagg attgcatatt gccagtgcta caaaaatctt gcgagcttct
    24721 tctagttcag aaaatgagca acattacttg cagctccttc caacagaacc ggtatttgaa
    24781 gtagaacaag tggcttattt ggataacgga actccgtttg agtactcgat tagtcgtcat
    24841 cgctatgatt tatttgaatt taattctttt gcattacgac attcctccta ggagaaaatg
    24901 tgaaaatgaa gccaatcttt tacaggctct agtttaagaa aaatttaaaa cagggcaaga
    24961 aggtcccatc tatgcttaaa tggtttctct tttctaaata agatggcttt aaaagagtga
    25021 tcgttttatc catcatgttg aaaaatatct tcgtatagct tatagagtag gtactgaaat
    25081 tgttcacctg atctacttct tatagttatt tagttttaaa tagtgtttca aacattctta
    25141 cactgacgag aagtttttga gtcttttctt gtaacacata tagtatactg aggttagaat
    25201 agtagactgt gacttctaac aaattgctag aaatgaattt caatctccca atttatttgc
    25261 ttatatatta ttttaatata ttaaataaat tctggatcat aatcatttaa aaaaatttta
    25321 tttttttatt tttcattacg aataatatag atgaagggga aagagtatga aaacagaact
    25381 gtttcttttg ctattagttc aaaaggagaa aaaatgaaag tagaaaatat ttcgtatagg
    25441 gtggatcatc gtatattgtt tgataatatt tcttttgata cttcgagttc agacgtgaca
    25501 ttaattactg gtaaaaatgg tacaggaaag tcaactttac tatagtggat tgaaactaga
    25561 atagtacaca tctacttcta aaatattgtt agaaatcgat ttgactatcc tgatctattt
    25621 gtcctgttct tatttcattt cactatatct caaattgagt atgacgaagt gcgctcccat
    25681 gtcctgggaa cgcactttct tcatattttt catattcttg aatccatcga taaagactat
    25741 tgggatgaat ttttaaagtt gaactaatca tttttacagg atgaggttta cagcagagag
    25801 tttgaaggct ttatcaaagg tttttcttgg cataatgact tttcctcgtt tccacttaat
    25861 tttgtgtcta ctttattata ccaagtccac ccttaagtta gataataaat ctaacttaag
    25921 gaagctagaa ggatgagaat ccaggtggtc aagagtccca aacttaagct gattgggaca
    25981 cccagaataa tttgcttttt gaaggcaagg ccacgttcct ctatattggg aagtgagagt
    26041 tgaatgagag aaccagctga tgaaaagggt gagatattag tagatagagc gccaataacg
    26101 gtggctgttg tgagtaagtg aatatcaatc tggggatttt gagcactgat gatagcaatg
    26161 atgggaaaga gggctggagc tacaacggat agggtggaac taaagagtga catcaccccg
    26221 gctatcacac aaaagaacag aggtaaccag aaatgaggaa tggatgttgt catgaggtgc
    26281 cctatcagtg tgactaaacc tgacttgacc gctagagaca ttagtaagct catgccgcag
    26341 agcatgataa ttgtagccca gggaacttta gccaaaatgg cttcttgctt ccctaatttg
    26401 agccttaagg cgaggcagac catgagtatt gagacaaagc caatatcaaa tgtttttcga
    26461 taagtagcta tccaggcgat gtttgggaaa atgagatgca acaagggaaa aagccaaacc
    26521 aaaaccatgc tgctgatcat gagcaaggtg gtttgtcttt gaaccttgct gaggagtggt
    26581 ggttggtcaa tagtcaagga tgagtttgtt cttcccttac tatagtgact gtaacaggat
    26641 aataaaagca agacaatgag tgggtagata atgctgacga taaagatatg attgccaagt
    26701 gaaaaagctt gctcttccca tcccatttgc ttaaacaggc cttgaaagac aatgcctgag
    26761 ctactggtta tcaaattagc ccctcctgaa gctccccaat tgacggcttg agctccaatc
    26821 aaagggtgtt tgtccgcttt ttgacagaga gtaatcgcta gaggacagca aacggccata
    26881 gtagtgaaaa atccagcacc taaagcagac aaaagggttg ccatcaggta taaaatcatg
    26941 tagagggcgt tagggtaggt gcgtgtgcgg tagagaatgt gttgagccaa aacatcaaga
    27001 gtaccgttag ttattgcaaa gttataaaag agagagacgc taaaaatggt aaaaaagagt
    27061 gaggttggcc aaaaatgaag aagttctttg gggcttaatc ccatgagagt ggttgcgatg
    27121 aggtaagaaa aagcaatagc cagcaggcca atattgattt tggtgcggta accaattcca
    27181 atggctagag caatggcgct aatcattatt aaatgaatca ttgaattgtc ctttcagtta
    27241 gaatatggaa ataggttggc aattttggcg ctcaaaagac cacctgtttc ctattggtac
    27301 ttgactatta tacacaaaaa aaatacaatt gtcttgacaa ttgtattgac acttgttaga
    27361 attaaaaatg aggtattcag gcttgtgatt tcctatggaa gttaatagtg attgcctcta
    27421 atgcttacaa gtgatattaa aaatagagga cctagtgatg tcaatcattt caactgattt
    27481 aacccctttt caaatagatg atacattgaa agcagccttg cgagaagatg ttcattccga
    27541 agattacagt accaatgcca tttttgatca tcatggccaa gccaaggtgt cgctttttgc
    27601 caaggaagct ggtgttttag cggggctaac cgtttttcaa agggttttta ccctatttga
    27661 tgccgaggtg accttccaga atcctcatca atttaaggat ggggatcgtt tgactagtgg
    27721 cgatttggtt ttagaaatca taggctcggt gagaagtctc ttaacatgtg aacgcgttgc
    27781 cttgaatttt ttacaacatt tatcagggat tgcttcgatg acagctgctt atgtagaagc
    27841 cttaggcgat gattgcatta aggtatttga tactcgaaaa actactccta atttacgtct
    27901 ttttgagaaa tatgcagtga gagttggcgg tggctataat catcgcttta atttatcaga
    27961 tgctatcctg ctaaaagaca atcacattgc ggcagtaggt agtgttcaaa aggcaattgc
    28021 tcaagcgcgt gcctatgccc cttttgtgaa aatggtcgag gtggaagtgg aaagccttgc
    28081 tgctgccgaa gaagctgcgg cggcgggtgc tgatattatc atgttggata atatgtcatt
    28141 ggaacagatt gaacaggcca ttaccctaat tgcaggacgt tctcggattg aatgttctgg
    28201 aaatattgat atgaccacta ttagccgttt tcgtggttta gcgattgatt acgtctccag
    28261 tggtagttta acccatagtg ctaagagtct tgatttttcc atgaaggggt taacctacct
    28321 tgatgtctaa gttgtaaaat aaactaactt tttaaaggat gtctttcctc tagaacgagt
    28381 tttatgtcag atagtttaaa cgcctctt
//
LOCUS       DAVBCA010000026        27275 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.026, whole genome shotgun sequence.
ACCESSION   DAVBCA010000026 DAVBCA010000000
VERSION     DAVBCA010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27275)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27275)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27275
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.026"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            228..1910
                     /locus_tag="VQU19_001050"
     CDS             228..1910
                     /locus_tag="VQU19_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2480310.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQTAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLANLDNMSIS
                     KGQVQLQNELVKETPELQSLFKLEDVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHRKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            1895..2725
                     /locus_tag="VQU19_001051"
     CDS             1895..2725
                     /locus_tag="VQU19_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET2480311.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVASLLLSLQNQGRFYNPWK
                     "
     gene            2918..3421
                     /locus_tag="VQU19_001052"
     CDS             2918..3421
                     /locus_tag="VQU19_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HET2480312.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKVYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     regulatory      3475..3709
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            3874..4437
                     /locus_tag="VQU19_001053"
     CDS             3874..4437
                     /locus_tag="VQU19_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET2480313.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTIGLTVAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYILLKPTLKHYER"
     gene            4451..5077
                     /locus_tag="VQU19_001054"
     CDS             4451..5077
                     /locus_tag="VQU19_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HET2480314.1"
                     /translation="MKGSFALLLFVILGYMVKFYPEMLVNFDQSIQTAIRGDLPDYLT
                     ILFRSLTRLIDIPVIITWVVIIAFVFYRKRWKIESFFMLGNLTLAGLLIVTFKNIYQR
                     PRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDQVWRKIVQIVLGLYLVS
                     VLVSRVYLGVHYPSDVLASLCVGLGALFIEFPFYDKLRFQWRFKGKQK"
     gene            5189..6061
                     /locus_tag="VQU19_001055"
     CDS             5189..6061
                     /locus_tag="VQU19_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000525616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2480315.1"
                     /translation="MGMLLATRLKNKRKELKLSQKELAEGICEQGQISRMEQGKYSPG
                     SELLFQLSKRLKVSMDYFFEDTEVSSLENIDKFKELSKKFLDEREYESLHYIYELEKS
                     KRARLSAKDQIYLDWIDTLVQFCYLNHQTGAVAKLEKILLSLKKSDFYYLQLGNTLAN
                     FYFDMGQEDTYQELYQLLKENLQSLSVHHLEQLELMIKFRYNYCRYLWLNERTSEAIE
                     EITETIAICKRYNSSYRLADLYCLLGSISEGFAERDRILGFYQVSYQLYKHEENQRMM
                     LEIEKEMKLLESED"
     gene            6191..6328
                     /locus_tag="VQU19_001056"
     CDS             6191..6328
                     /locus_tag="VQU19_001056"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480316.1"
                     /translation="MKRSQVVKRCILIALLLLFLLNVLSGSLSVTTRGVDPRPAYGVS
                     L"
     gene            6752..7666
                     /locus_tag="VQU19_001057"
     CDS             6752..7666
                     /locus_tag="VQU19_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000781144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
                     /protein_id="HET2480317.1"
                     /translation="MKLYQINDGIQIFESSNLEKIVIRNYRNGKKITIDHQPLLKKLL
                     LFLEVPKREEEILLYLPELSNKTLRSVLTNFMSLNIIHCQDTLIIHKKINILIIGLGT
                     TGGYLADGLCRSNINSKLFLLDKDRVDETNVGRQIYLRDDIGQYKVDVFKQKFSDKEI
                     KVFKIFINSKKDLEKICKREGIDLVIQCGDSPSPRELGKIVNTVCDTLQIPYIVNTGY
                     MSNVVPLPEFYYPNNRYNFNYKHQFSDEKLLFSQVLSKADYMVAIQSSFVMLMQIKNF
                     IFNEEPIYYGYRGYYNSVTLAWEVEKID"
     gene            7659..8672
                     /locus_tag="VQU19_001058"
     CDS             7659..8672
                     /locus_tag="VQU19_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480318.1"
                     /translation="MTKYLELDYSHSYILEGFRKNDAFIENHKECLDMLSDKIWRDNK
                     YMNTEKNISSPTRTILSRYTCNILSSLFIDISKNSIEKLIVTCENSDLNWIYNYYKSV
                     YNGVFCELRQLIQQYCKVKDKYEKWLFIKAIINQGIRQNEKEVVEFFLKQLKDNNQGI
                     FDYINSFSFYLLKFYSKDKSRIFLEEQLDIDDFLGSDKEDYARSLVFKNYASLLPDTS
                     ELKRNIMEKCLSQTPQDTDLWKEWFETYASQKEIRQKATEIFKHGYSDISLLKLVKIE
                     PDDTESLIRMIILCTSDLNSNIARYLISFLSDGRLKEFLELFVENFDFLNIIEGKTSE
                     INF"
     gene            8656..10248
                     /locus_tag="VQU19_001059"
     CDS             8656..10248
                     /locus_tag="VQU19_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001236730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2480319.1"
                     /translation="MRLIFRIIRKDIILYSILTFLLSIAMVSEAFLMQFIVDSIKFGE
                     KKYVLISIFIVIFLILQTLLYYYQQFLTAVLSKKSAYEYRKLIFKNIQQTSLRLVTGE
                     KNDSILASLTTQIDQIEYNYFYSVYWGGYLLCQLVVAIVMSLYLNPLMSVLTICLSLP
                     NLFVALLFKNSLEQKQEELINETNSSIAVTQDLIEGITDWKIANREPNIFRVFESKTL
                     KLLEKQVKVEKFQYIVVSLNQLFSNVLYFGSWIVGGFLIIRGQLSLGSLIAFSQLLAR
                     ISYPVYASSDLLSKYISGKKIVEILSKEFIFSDESRNYPDEFNVISFEHYFTNIDEKD
                     MPFDKEFYKNKKYLLKGKSGSGKTTILKSILREYDDYSGIVKINGVDVRDIKESVLFD
                     NIAYVSQKPHLFSASLRDNLTLFSEDFTDNEIVEVLKFVELSKWANKDCLDMMLSNDD
                     IKLSGGEVKRVSLARALLMNKNILLLDEFSAGIDYETLLKIEKKLIDLDKMIIYVTHV
                     DIDRSGKQFDDVIDLDCLFISS"
     gene            10440..11343
                     /locus_tag="VQU19_001060"
                     /pseudo
     CDS             10440..11343
                     /locus_tag="VQU19_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001091364.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            11361..11498
                     /locus_tag="VQU19_001061"
                     /pseudo
     CDS             11361..11498
                     /locus_tag="VQU19_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
     gene            11526..11867
                     /locus_tag="VQU19_001062"
     CDS             11526..11867
                     /locus_tag="VQU19_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480320.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETIQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLKNHI
                     LPLWIGMVSFF"
     gene            11840..12151
                     /locus_tag="VQU19_001063"
                     /pseudo
     CDS             11840..12151
                     /locus_tag="VQU19_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            12279..12866
                     /locus_tag="VQU19_001064"
     CDS             12279..12866
                     /locus_tag="VQU19_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HET2480321.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            13256..14863
                     /locus_tag="VQU19_001065"
     CDS             13256..14863
                     /locus_tag="VQU19_001065"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HET2480322.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDVEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
     gene            complement(15422..17053)
                     /locus_tag="VQU19_001066"
     CDS             complement(15422..17053)
                     /locus_tag="VQU19_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HET2480323.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGVGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGITITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            17346..22325
                     /locus_tag="VQU19_001067"
     CDS             17346..22325
                     /locus_tag="VQU19_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HET2480324.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHARENKLEKAEGVAIASETASPASNEAATTE
                     TAEAASAAKPEEKASEVVAETPSAEAKPKSDKETEAKPEATNQGDESKPAAEANKTEK
                     EVQPDVPKNTEKTLKPKEIKFNSWEELLKWEPGAREDDAINRGSVVLASRRTGHLVNE
                     KASKEAKVQALSNTNSKAKDHASVGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDA
                     GHRNGVPVYGTLFFNWSNSIADQERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFI
                     NQETTGDLVKPLGEKMRQFMLYSKEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYN
                     YQFMQPEGDKVPADNFFANFNWDKAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKT
                     KVKWNDILDENGKLRLSLGLFAPDTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGD
                     KDWYGIANLVADRTPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWR
                     WWQTSTGEKLRAEYDFTDAYNGGNSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVA
                     HKGGKGSKVYMAFSTTPDYKFDDADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFF
                     EHEGAVKDYQFNLGQLTISDNHQEPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADF
                     YEVYEKDGDSWKLLTGSSSTTIYLPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTT
                     FDWGMTVKDTSLPKPLAENIVPGATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSA
                     QLSGSVDIRLTKPRTVVRWVMDHAGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEV
                     RGNKAHVTDITLDKPITAQDWRLNVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMA
                     KAAARSLGNNKVQVGFADVPAGATITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQ
                     SGLLYYRTQLPGKEISNVLAVSVPKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLR
                     VQYEGGTEDELIRLTHAGVSVSGFDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEAS
                     PKTILGIEVSQEPKKDYLVGDSLDLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQK
                     TGRQTLTLRYQGHEVNFDVLVSPKAALNDEYLKQKLAEVEAAKNKVVYNFASPEVKEA
                     FLKAIEAAEQVLKDHETSTQDQVNDRLNKLTEAHKALNGQEKFKEEKTELDRLTGEVQ
                     ELLAAKPNHPSGSALAPLLEKNKALVEKVDLSPEELATAKQSLKDLVALLKEDKPAVF
                     SDSKTGVEVHFSNKEKTVIKGLKVERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVD
                     LSYASIVKIPIEKDKKVKKVFFLPEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESA
                     EKPQPAKPAPQNKVLPKPTYQPASDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRV
                     IIQGRDGLLRHVFEVDENGQRRLRSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQ
                     NTAVKSEEASKQLPNTGTADANEALIAVLASLGLASLALTLRRKREDKD"
     gene            22415..23611
                     /locus_tag="VQU19_001068"
     CDS             22415..23611
                     /locus_tag="VQU19_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HET2480325.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            23747..24274
                     /locus_tag="VQU19_001069"
     CDS             23747..24274
                     /locus_tag="VQU19_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HET2480326.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETILYVFVRVLETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            24351..24707
                     /gene="glnR"
                     /locus_tag="VQU19_001070"
     CDS             24351..24707
                     /gene="glnR"
                     /locus_tag="VQU19_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HET2480327.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            24744..26090
                     /gene="glnA"
                     /locus_tag="VQU19_001071"
     CDS             24744..26090
                     /gene="glnA"
                     /locus_tag="VQU19_001071"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HET2480328.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYIAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(26186..26305)
                     /locus_tag="VQU19_001072"
     CDS             complement(26186..26305)
                     /locus_tag="VQU19_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HET2480329.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            26793..27275
                     /locus_tag="VQU19_001073"
                     /pseudo
     CDS             26793..27275
                     /locus_tag="VQU19_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187281.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
BASE COUNT         8594 a         4569 c         5792 g         8320 t
ORIGIN      
        1 aaccatacct acggcaaggc gaaactgacg tggtttgaag agattttcga agagtataaa
       61 atgatgggga aggctgggca actagtcttt ttcgatgttt atagattagt taggcaagta
      121 agctaggata ggaatctttt tggtgctaag attttaagag aagagactgc aagaagggct
      181 tgatttatga taaaatagaa gtctaagaag cgaatgaaga gagtaagatg aaagaagcta
      241 taattgagtg gaaggatttc tctttccggt atgaaacaca acaagaaccg accttgcaag
      301 ggatagactt gaccatttac aagggagaga aagtcttaat tgttggacca tctggatcag
      361 gtaaatctac cttgggtcag tgtttgaatg ggattattcc caatatttac aagggtcaga
      421 catatggaga atttttgata aagggtcaaa cagcctttga tatgagcatc tatgataagt
      481 ctcatctggt tagcacagtt ttgcaggata cagatgggca gtttattggc ttgtctgtgg
      541 cagaagattt ggcgtttgct ctggaaaatg atgtgacagc cctagatgag atgaaaggtc
      601 gtgtttataa atgggctgaa aagctggacc ttcttccttt actggatcag cgtcctcagg
      661 atttgtcagg tggacaaaag cagcgagtca gtctggctgg tgtcttgatt gatgaaagtc
      721 cgattctctt gtttgatgag ccactcgcca atctagatcc caagtcaggt caggatatta
      781 tcgaattgat tgaccagatt cataaggaag aggggacgac gactcttatt atcgagcacc
      841 gtttggagga tgttctgcat cgccctgtgg atcggattgt cttgataaac gatggtcgta
      901 tcctttttaa tgggagccct gaccagttgc ttgcgactga tttattgact caaaatggaa
      961 ttcgagaacc cctttatcta accactctcc gtcaattagg tgtggactta gtcaaggaag
     1021 aacagttagc gaatctggat aacatgtcta tctcaaaagg tcaggttcag ctgcagaatg
     1081 aactggtaaa agaaactcca gaattgcagt cactctttaa attagaggac gtgtctttct
     1141 cttatgatga tagaccgatt ttaaaatccc tacatttaga tattaaaaag ggtgaaaaga
     1201 ttgctattgt cggaaaaaat ggagcaggga aatcaactct agccaaggct ataagtagct
     1261 ttattcagac ggaaggacgc tatctttggg aaaaacagga tataaaaggc gattctgttg
     1321 cagagcgggc ggaacgagta ggctatgtgc tacaaaatcc taatcaaatg atttcaacca
     1381 atatgatttt tgatgaggtg gctctagggc tccgtttgcg aggtgtggat gagaaggaaa
     1441 ttgaaacgag agtctatgaa accttgaaaa tctgtggact ttatgaattc cgtaattggc
     1501 ctatttctgc cctgtcattt ggtcagaaaa aacgtgtcac cattgcttca attttggtct
     1561 taggagctga aattattctc ctagatgaac cgactgcagg tcaagatcag aagaactata
     1621 ctgagattat ggaatttctc gaagagttac atcgaaaagg gcataccatt gtcatgatta
     1681 cccatgatat gcaattgatg ctggattatt cagaccgagt ccttgtcatg gtggatggag
     1741 aattgattgc cgatactgtt ccagccagtc tgttgagcga tcctgagctg ttagtaaaag
     1801 ccaatctaaa agaaacctcc atctttaact tggctaagaa actagatgtg gatccactgg
     1861 atttaacggc attttacaaa gaaaggagag agggatgcaa gctaaattaa tcggttacca
     1921 gcatagagat actgtgattc atcgcttgtc aggagctggg aaacttctct ttttcattct
     1981 ggtatcattg gcggccatga ttagctatga taccagaatg ctcttgctga ttgccatctt
     2041 ttcagtcttt ctcctctatt tatcagaaat tcgctttaaa gatgtttcct ttgtagccgt
     2101 ttttgcgacg gtatttgccg ttttaaacgt tttgatggtc tatctctttt ctcccgagta
     2161 tggggttgga ctttatggag agagaagtgt gatttggcag ggaatcggtg tctacactct
     2221 aaccagccag gagctctttt atctgctaaa tttggccatt aagtatcttt gcaccattcc
     2281 tctggctatt atctttttga tgacaaccca tcctagtcag tttgcttcca gtttaaatca
     2341 aattggtgtg ccctataaga ttgcttattc tgtcagcctg accttgcgct atattccaga
     2401 tttgcaggaa gaattcttta ctatcaagat gtctcaggag gcgcgtggga tggaattatc
     2461 caagaaagct tctcttatgc aacgaatcaa aggcaatctg ctcattatta cgcccttgat
     2521 ttttagctcg ctagaacgca ttgataccat tgcgactgcc atggagcttc gccgctttgg
     2581 gaaagaaaaa aaacgcacat ggtatagtta tcaggccttg aaaaaaggag actatattac
     2641 cttgctcttg gcaaccttgt ttttagtagc tagtttacta cttagcttgc agaatcaggg
     2701 acgattttac aacccttgga aatagcttga aaaaattgaa aaaatcaagt cgtttctatt
     2761 gacaatgatt ctgaaagtgt tatactaaga aagtagtttc gctgatttac ttcaaacctg
     2821 ttgtgaggta agttaacgat gccttaacca cgctgtttgc tgagcttgac tccgggcagt
     2881 gtggctattt ttttgcaatg gtgaaaggaa gcaagtcatg acaaatcaca ttgtattatt
     2941 tgaacctcaa attccacaaa atacgggcaa tatcgcgcgt acttgcgctg cgaccaattc
     3001 tcccctccac atcatcaagc ctatgggctt tcctattgat gaccgcaaga tgaagcgggc
     3061 tggattggat tactgggata agctagagat ttatttttac gagagtttgg aagatttcat
     3121 atctcagatg aagggaaaac tctatctgat ttcgaaattc gcggaaaaag tctattctga
     3181 ggtggattta tcgactgacg aggaccatta ttttctcttt ggacgtgaag acaagggctt
     3241 acctgaagat tttatgcgag aacatcctga gaaggctctc cgtattccca tgaatgatga
     3301 acatgtccgc agtctcaatg tgtctaatac cgtctgcatg attgtctatg aggctcttcg
     3361 ccagcagaac tttgcaggtc ttgaactcgt ccatacctat gaagtggata aattgaaata
     3421 aaaaatgaaa atgaacaaaa tgcttgcgct tgcaagcgtt ttttgttatg ataaaagagt
     3481 cttcagggca gggtgtgatt cccgaccggc ggtgacttta actaggaaat gatcttttcc
     3541 ttttatactt tgttgacaag ctttgcctaa ccagaagtta tgcctacagc ttgtcgccta
     3601 gtctaaaaga aaaatctcta tttccttctc tttaaagaag tccgcgagcg caagctgatg
     3661 tggtgagatt ccacaaccga cagtatagtc tggatgggag aagacgaaag aatagctttg
     3721 tctgttttga tagatttata gccggattgt aaccacttgc tttgtttttc tttaatagag
     3781 taggagggaa cttttgggat ataaaaagtg agaatagata gaggaatcct ttccaacttc
     3841 ttctgatttt atagaaaatt ggaggaacct gttatgacaa acacacgtcg actttcgacc
     3901 attgcaattt tatcagccat ctcatttgtg ctgatgtact ttgactttcc gcttttacca
     3961 gcggcatctt tcctcaagat cgaatttagt atcttgccag tccttgtggg tctggtggtc
     4021 atggatttgc ctgctgctct aggagtgctc ttgcttcgct cactcttgaa attgcttctt
     4081 aacagccaag gagtgaatac ttacattggt ttgccgatga atatcgtagc tttgggagtt
     4141 tttgtcatcg tatttgcttt gatttggaaa aaggaacgga caacccttcg tttcctacta
     4201 ggctctctag ctgggactat tggtttaacc gtggctatgt tagttctcaa ctatgtttat
     4261 gctgttcctt tgtacgctaa gtttgctaac tttgatattg gaaaaatttt gggactttcc
     4321 aactacctaa tgaccatggt attacctttt aacttgattg aaggtgtaat cttttccgtt
     4381 tcattctggt tgttgtacat tctcttgaaa ccaaccttaa aacattatga aagataaaca
     4441 aacattttta atgaagggca gttttgccct tttacttttc gttattcttg gctatatggt
     4501 caaattttac cctgaaatgt tggtcaattt tgaccaatcg attcagactg ccattcgagg
     4561 agacttacca gattatttga ctattctttt tcgatccctc acacgtctga ttgatattcc
     4621 agtgattatc acttgggttg tcattatagc ttttgtcttt tatcgtaagc gatggaagat
     4681 agaaagtttc ttcatgctgg gaaatctgac tttggcaggt cttttaatcg tgacctttaa
     4741 aaatatctac cagcgcccac gaccagctat cttacatctg gtggaggaga agggattttc
     4801 cttcccaagt gggcattctc tggctgtaac gctgatggta gggactttga ttgttattct
     4861 tagtcagcgg attaaagatc aggtctggag aaaaatcgta caaatcgtcc ttggcctcta
     4921 cctagtcagt gtgctggtat caagagtcta tctgggagtt cattacccat cagatgttct
     4981 tgccagtctc tgtgtgggct tgggagccct gtttatcgag tttccctttt atgataagct
     5041 ccgcttccaa tggcgattta aaggcaaaca gaaatgatgg aaaagataaa aaattgtaca
     5101 aatacaaata gaaccatatg aaatatatac ttgaaacatg ttttggagtt tgatatattt
     5161 taataaataa agcaaggagg aagaaagtgt gggtatgtta ttagcgacac gcttaaaaaa
     5221 taaaagaaag gaattaaaat tatctcaaaa agaattagct gaggggattt gtgagcaagg
     5281 gcagattagc cgtatggagc aaggtaaata ctcacctggg tcagaattac tctttcaact
     5341 atctaagcga ttgaaggtga gcatggatta tttctttgaa gatactgagg tttctagttt
     5401 agaaaatatt gataagttta aagaattatc taagaaattt ttggatgaga gggaatatga
     5461 atctctccat tacatctatg aactggaaaa atctaaacgt gctcgtctat ctgctaaaga
     5521 ccagatttat ttggattgga ttgatacatt agttcaattc tgttatttaa atcatcaaac
     5581 aggggcagtt gcgaaactgg aaaaaatact gttatctctg aaaaaatctg atttttacta
     5641 tctacaactg ggaaatacct tggctaattt ttattttgat atggggcagg aagacacata
     5701 tcaggaactc tatcaacttt taaaagagaa cctccagtca ctatctgttc atcatttgga
     5761 acagttagaa ttgatgatta aattccgata taactattgt agatatttgt ggttgaatga
     5821 acgaacatct gaagctatag aagaaattac agaaacgata gctatttgta aaagatataa
     5881 tagtagttat cgattagcag atttgtattg tttattggga agtataagcg agggctttgc
     5941 tgaaagggat aggatactag gtttttatca agtatcttac cagctttaca agcacgaaga
     6001 gaaccagaga atgatgctag aaattgagaa ggaaatgaaa ttattggaaa gtgaagatta
     6061 agcaaaaaga tttgtattct tagataactt taatacatat tataaaaaaa ataaaaaaat
     6121 atcataaaaa ttattgacaa accaaaattg atgtgttaga atatcaccaa tagttaagga
     6181 ggtttagaag atgaaaagat ctcaagttgt caaacgatgt atattaattg ctttattgct
     6241 tctatttcta cttaatgtgt taagtggttc tttatctgta acaactagag gagttgatcc
     6301 aagaccagca tatggagttt cgctttaaag ttgtgcatag ttcttctttt atagacggag
     6361 agtttttctc aatagtaagt gattcaaatt ttgatggatg attttccatt aaattaagtg
     6421 attgcgaaaa ctttttgaaa tacattctct ttggatattg aaagtttgtt ttggattttt
     6481 ttatgaagct tatcttagct gttagattgg ggttttatgg gatttgtcct caccgggaaa
     6541 aaatcttaaa tctttgaaga aagaggtttt tatcttatgg ttagagatac atcagaagaa
     6601 attgaagtta ttgacttgtc ttctatgacc gtttcctact catctgttat gctaggaaac
     6661 tcttggatga cgtggaattg atttattaag atagattatt tggtttttac caaaaatctg
     6721 tctttttaat ttttaaagga ctaatggtga tatgaaacta tatcaaataa atgatgggat
     6781 acaaattttt gaaagtagta atcttgaaaa aatagtaatt agaaattata ggaatggtaa
     6841 gaaaataact atcgatcacc aaccattatt aaaaaaatta ctactattcc ttgaagttcc
     6901 taaacgtgaa gaagaaattc tattatatct tccagaatta tcaaataaaa cattacgaag
     6961 tgttttgacg aattttatga gtttaaatat aattcattgt caagatacat taataattca
     7021 caaaaaaata aacatattga taataggttt agggactacg ggtggatatc tggcagatgg
     7081 gttatgtcgt agtaatatta attcgaagct atttctttta gataaggatc gtgtagatga
     7141 gactaatgta ggtagacaga tttatttaag agatgatatt ggtcaatata aagttgatgt
     7201 atttaaacaa aagtttagtg ataaagaaat aaaggtattc aaaattttta ttaatagtaa
     7261 gaaagatttg gaaaagattt gcaaaaggga gggtatcgat ttggttatac aatgtggtga
     7321 ctccccttca cctcgagaat taggaaaaat tgtgaataca gtatgtgata ctctccagat
     7381 accttatata gttaacactg gctacatgag taatgtagtt cctttgccag aattttatta
     7441 tccaaataat agatacaatt ttaattataa gcatcaattt tcagatgaaa agttactgtt
     7501 ctcacaagtt ttgtctaaag ctgattatat ggtggcaatt caatcatcat ttgtaatgtt
     7561 aatgcaaata aaaaatttta tatttaatga agaacctatt tattatggtt ataggggata
     7621 ctataattct gtaacattag catgggaggt ggaaaaaatt gactaaatat ttagaattgg
     7681 attattctca ttcatatatt ttggaaggtt ttagaaaaaa tgatgcgttt attgaaaatc
     7741 acaaagaatg ccttgatatg ttatcagata agatttggcg agataataaa tatatgaata
     7801 cagaaaaaaa catatcatca ccgacacgaa caatcttatc acgctatact tgtaatattt
     7861 tatcgtcttt gtttattgat attagcaaaa atagcataga aaaattgata gtgacatgtg
     7921 aaaatagcga tcttaattgg atttataatt attataaatc ggtttacaat ggagtatttt
     7981 gtgaattgcg acaacttata caacagtact gtaaggtgaa ggataagtat gaaaagtggc
     8041 tttttataaa agctattata aatcaaggta ttcgtcaaaa tgagaaagaa gttgttgaat
     8101 tctttttaaa acaattgaag gataataatc aaggtatttt tgattacatc aatagtttta
     8161 gtttttatct attaaagttt tattcaaaag acaaatctcg cattttttta gaagagcagc
     8221 tagatataga tgattttttg ggatcagata aagaagatta tgctaggtct ttagttttta
     8281 agaattatgc ttctctattg cctgatactt ctgaattaaa aagaaatatt atggaaaaat
     8341 gtttaagtca aacacctcaa gatacagatt tatggaaaga atggtttgaa acttatgcca
     8401 gtcagaaaga gattagacaa aaagcaacgg aaatatttaa gcatggttat tcagatattt
     8461 cgttactaaa attagttaaa attgagcctg atgacactga gagtttaatc agaatgatta
     8521 tcttatgtac cagtgaccta aatagtaata ttgcaaggta tttgatttca tttttgagcg
     8581 atgggcgatt aaaagaattt ttggagttat ttgttgaaaa ttttgacttt ttgaatatta
     8641 ttgagggaaa aactagtgag attaattttt agaataatta gaaaagatat tatattatat
     8701 tctatattaa catttttgct atcaatagcg atggtaagcg aagcattttt gatgcaattt
     8761 attgttgatt caattaaatt tggtgaaaag aagtatgttt tgatttctat ttttattgta
     8821 atttttttga ttcttcagac tttattgtat tactatcaac aatttcttac agctgtatta
     8881 agtaaaaaat ctgcatatga gtaccgtaaa ttaattttta aaaatattca gcagacttct
     8941 cttaggcttg ttacaggtga aaaaaatgat agtattctag cttctttgac aacgcaaatc
     9001 gatcaaatag aatataatta tttttattct gtttattggg gtggatattt gctttgccaa
     9061 ttagtggtag ctatagttat gtcgctttat ctaaatccat tgatgtctgt attaaccatt
     9121 tgcttaagtc tccctaattt atttgtagca cttcttttta aaaactcctt ggaacaaaag
     9181 caagaagagc taattaatga gacaaattcc tcaatagcag ttactcaaga tttaattgag
     9241 ggaattactg attggaaaat tgcaaataga gaacctaata tatttagagt gtttgaaagc
     9301 aaaacattga agcttttaga gaagcaagtg aaggtagaaa aatttcaata cattgttgtt
     9361 agtttaaatc aattgttttc aaatgtttta tattttggta gttggatagt aggtggattc
     9421 ttgattatac gggggcaact ttcattaggg agtttgatag cgttctctca attattagca
     9481 agaatttctt accctgttta cgcttcttcg gatttattgt caaaatatat tagcggtaaa
     9541 aaaattgtag aaattctttc taaagaattt atattttcag acgaaagcag aaattatcca
     9601 gatgagttta atgttatttc atttgaacat tattttacaa acattgacga aaaggatatg
     9661 ccttttgata aagaatttta caaaaataaa aaatatttgt tgaaagggaa aagtggtagt
     9721 gggaaaacaa caattttaaa atcgatttta cgagagtatg atgattatag tggaattgta
     9781 aaaattaatg gggtagatgt tagggatata aaagagagtg ttctttttga caatatagct
     9841 tatgtttccc aaaaacctca cttgttcagc gcaagtctta gagacaacct gacattattt
     9901 tctgaagact tcactgataa tgagatagtt gaggttttaa aatttgttga attatctaaa
     9961 tgggctaata aagattgctt ggatatgatg ctttcaaatg atgatataaa attatcagga
    10021 ggggaggtca aaagggtttc tttagctcga gccttattga tgaataagaa tattctgtta
    10081 ttggatgagt tctctgctgg gattgattat gaaacattgt taaaaataga gaagaaactc
    10141 attgatttgg ataagatgat tatttacgtg acgcatgtgg atatagatag atccggcaaa
    10201 cagtttgatg atgtcattga tttggattgt ctttttatat cctcgtgaca tgagagttga
    10261 gtcagttgaa ttattttgtc actctgttta gttcttgttg gtagtgtcag gtaatctttg
    10321 ttaatttttc aggaagtcta ttgaaatatc ctcttggtta tatattacga ggagtaatta
    10381 atggatattc tcgagaattc aatacaacaa tttgattcta aagttaagta tgtttcttta
    10441 tttgcggaat caatctttta tcagatacca tgagctattt tgcaggtgct atgatttctc
    10501 ctttgtatgt gaggattatc ggagatgata tgacagatgc tatgggggtt agacaggcaa
    10561 ctgctggtgt agttaatatt ctcagcaacc ttataggggg agttttgatt gggggtcatc
    10621 agtcttcaga tgtttgtagg tttgaatgct ttgacctttc tttttgcact gttgggtgtg
    10681 gtgtttattc gtacttcttt gagagatatt gaggaacaga tggaggttag taaaagatta
    10741 gccgcaaaat cttttggaga gcatttcctc cattcaatga agatattgtc aagttttcca
    10801 gccatcatca aattaatatt cattgcagct atgaaccaag tgattttaag cattattatc
    10861 cctttaacga ctttgatgtt aatccatcat ccatttatct tctttgacac tgggaaatcc
    10921 attgcagcat tgtcagtggt tattttttca ggaacgattg tgggaagttt tttgagtgga
    10981 ggtatcctaa aaaatattcc cataaaaatg attgtctact ttgaagaaat tatgcatctc
    11041 tgtattctct tttcttggtt gaccaatcat ttcctccttt tattggtagt tgtcttctta
    11101 tgcgcagttg cagtaggaat gatggggcct cggattttca accttgtatt ctcgatggtt
    11161 ccagaagaag tcatgggaac catccagtca gtgcttggag tattcaatgt tgttgtacca
    11221 ggaattctta gcatgctcat cgttgcctta gcgagtgcta caaacctaaa aatcacagtg
    11281 cttccacttt ttatttttgt attgactgcc ttagcaattg tgaaagcaat gaaaatagag
    11341 taatagtagt atgaactact gtctcttttt gggtgggagt tcattaccca tcagacgtcc
    11401 ttgccagtct ctgtgtgggc ttgggagttt tgtttatcga gtttcccttc tatgacaagc
    11461 tccgcttcca atggcgattt aaaggcaaac agaagtgagt atcgaattcc cttgaggaga
    11521 aagaaatgaa agtcaatata gcagatcttc atccgactca actatattta tcagaaaaga
    11581 agttgcaaga tattcagatg ctttaccagt cggcagaaac aatccaagtc gatccaatca
    11641 gtattcttgc ctttggagat tgtttgctga ttacagatgg gcatcacagg gcttatcagg
    11701 ctttattggc aggtcgggat acgatttctg ctgagtggga tagagatggt ggtgatgaac
    11761 tatatcatct ctatgcgcaa gcttgcgagg aaagaaagat ttactctgtt tttgatttaa
    11821 aaaatcatat cttacctctt tggatcggca tggtgagctt tttttgattg aagtcaagga
    11881 gaagggagaa tggtttccaa ttggggatat tacactatct caggataatc tccccattgt
    11941 gattgggaat tccgcttacc aacatcgagg acttggaaaa aagattctaa gtgctttgat
    12001 tgaattggct cgagtaaaag gatggaaaga attgagagtc aaggaaatct acacctacaa
    12061 tcatgcttct aggaggtgtt tcaagtcgct tggatttgtg gaaaatggag caacagaaaa
    12121 aggaaggagt tttatattgg aattagtcta atcctgccac tttctccccc ttaacctttg
    12181 actattccgc aaaattatcg taaaataaag agtaaatgat aaaatgaggt cagagtctgt
    12241 tcgctctgac gatagtagta taaatgagga gaaacgcttt ggaattagaa gtatttgctg
    12301 ggcaagaaaa aagtgaacta tctatgattg aggtagcgcg tgctatatta gaacttcgtg
    12361 gtcgcgatca tgagatgcat tttagcgatc ttgtaaacga aattcaaaac taccttggaa
    12421 catcaaacag cgatatccgc gaagctttgc ctctgttcta cacagagttg aactttgacg
    12481 gtagcttcat ctcacttggg gacaacaaat ggggtcttcg ttcatggtat ggtgtggacg
    12541 aaatcgacga agaaatcatc gctcttgaag aaaatgacga cgatgaagta gcaccaaaag
    12601 ctaagaaaaa acgtgtcaat gcctttatgg atggtgattc agatgccatt gactacaatg
    12661 cagatgatcc agaagacgaa gatgcatacg aagcagatcc agctctttca tacgatgatg
    12721 aaaatccaga tgatgaaaaa aatgaagtgg aagcttatga tgcagaaatc aacgaaatcg
    12781 ctccagatga cttgggagaa gatgtggatc tcaacgaaga cgacgacgag ttttcagatg
    12841 acgacgctga aaccagcgag gaataagagt tagctattga caattatcct atttttaggt
    12901 atcatattgt ttgggcacct cttttagagg tcggggctcc ctagttctta gggagctatt
    12961 tttgtttttt caagaagtta tcttcttgta ttttatactc aatgaaaatc aaagagcaag
    13021 ctaggaaact ggccgtaggc tgctcaaaac actgttttga ggttgtagat aagactgaca
    13081 aagtcaggaa cacatatcta cggcaaggcg acgttgacgc ggtttgaaga gattttcgaa
    13141 gagtattagt tgtgaatctg gtgcagtcgt cccagattat tcttattagt agggtcttgt
    13201 tttctatatc ccctcgtagt taacaagacc ttgagcattt tagaaagagg aatctatgtc
    13261 tacgaaatat atttttgtaa ctggtggtgt ggtatcgtct attgggaaag ggattgtggc
    13321 agcgagtcta ggccgtctct tgaaaaatcg tggtctcaaa gtaaccattc aaaagtttga
    13381 cccttatatc aatattgatc cgggaaccat gagtccttac cagcacgggg aagtttttgt
    13441 gacagatgac ggagctgaga cagatttgga cttgggtcac tatgaacgtt tcatcgatat
    13501 caatctcaac aaatattcca acgtgacaac tgggaaaatt tacagtgaag ttcttcgtaa
    13561 agaacgccgt ggagaatacc ttggggcaac tgttcaagtc attcctcata tcacagatgc
    13621 tttgaaagaa aaaatcaagc gtgccgctct aacgaccgac tctgatgtca ttatcacaga
    13681 ggttggtgga acagtaggag atatcgagtc cttgccattc ctagaggctc ttcgtcagat
    13741 gaaggcagat gtgggtgcgg ataatgtcat gtatatccat acaaccttgc ttccttacct
    13801 caaggctgct ggtgaaatga aaaccaaacc aacccaacac tctgtcaaag aattgcgtgg
    13861 cttgggaatc caaccaaata tgttggttat tcgtacagaa gagccagctg gtcaaggaat
    13921 taaaaataaa ctggcccagt tctgtgatgt ggcaccagaa gccgttatcg aatcgttgga
    13981 tgttgaacac ctttaccaaa ttccactgaa cttgcaggca caagggatgg accaaattgt
    14041 ttgtgatcat ttgaaattag acgcaccagc agcggatatg acagaatggt cagccatggt
    14101 ggacaaggtc atgaacctca agaaacaagt taagatttcc cttgttggta agtatgtgga
    14161 gttgcaagat gcctatatct cagtggtcga agccttgaaa cactctggct atgtcaatga
    14221 tgtagaagtt aaaatcaatt gggtcaatgc caatgatgtg acagcagaga atgtagcaga
    14281 actcttgtct gatgcggacg ggatcatcgt accaggtggt tttggtcaac gtggtacaga
    14341 agggaaaatc caagccatcc gctatgcgcg tgaaaatgat gttccaatgt tgggagtctg
    14401 cttgggaatg cagttgacat gtatcgagtt tgctcgtcac gttttaggtc ttgaaggtgc
    14461 caattctgca gagcttgcac cagaaacaaa ataccctatc attgatatca tgcgtgatca
    14521 gattgatatt gaggatatgg gtggaaccct tcgtttggga ctttatccgt ctaagttgaa
    14581 acgtggctct aaggctgctg ctgcttatca caatcaagaa gtggtgcaac gccgtcaccg
    14641 tcaccgttat gagtttaata atgccttccg tgagcagttt gaggcagcag gttttgtctt
    14701 ttcaggagtt tctccagaca atcgtttggt agaaatcgtg gaaattcctg aaaataaatt
    14761 ctttgtagct tgtcagtatc accctgaact gtcaagccgt ccaaaccgac cagaagaact
    14821 ctacactgcc tttgttactg cagcggttga gaacagcaat tagcaaaatc agaacctttg
    14881 agaaaaatct cagaggtttt ttgcatacga tgatattgca atatatctga ggtagggggc
    14941 ctctgtatgt acctgctacc gttgaaatca atagcgactc cctcttgccc tgtgctagtg
    15001 aatggattta tcagtatatt gaaatgaaat aaaatttgaa caaattaatt cggaaagcca
    15061 aatcaatttc tagcaaagtt ttaggaactg gattgtatag tgaattgaaa taagatgtga
    15121 acatctctat cagaaaagtc aaattaattt atagaaatat tttagcagtc aagatgtact
    15181 gttatagatt caatacatta tactttttta atttaatcca ctatagtaaa atgaaataag
    15241 aacaggacaa atcgatcagg acagtcaaat cgatttctaa caatgtttta gaaatagagg
    15301 tgtactattc tagtttcaat atactatata tctgcagaat actctttcag tttcattcag
    15361 cctagtcttg cttaggaaaa agtaaaaagc catccaatta tgatggatag cttcttggtt
    15421 cttagatttg ttctgcaaaa accttttcag caaggttcat agcgtggtct gatacacgag
    15481 tgtagtgtga gatgatgtcg ataaagttga ccccagcttg tgttgaacat tcgcctttgt
    15541 tgaggcgttt gatgtgggtt tttctgagaa cacgttctat cttattgatt gcttcatgac
    15601 gttctacaag actgcgtgct ttttcaatat cattgttttc cacactatcc agagcatctt
    15661 tgataaagtc actagtttgg cggtaaactt cctctaattc tttcaaggcg gcatcagaaa
    15721 attcaacatt tttccgttga agatagtcag tcagattgag tagagcctcc gtgtggtctc
    15781 caatccgttc caaatcacgg gaggaatcaa ggatattggt aagcacttca ctttcttttt
    15841 ggctgagagc ttcgcttgaa agggcaatga gataacgtgt taattgctca tcgatggtgt
    15901 taattgcttc ttcggtttta tgcccttttt cagcaacttt ttcatccaag tcaatgatgt
    15961 acttatagga aaggtcaaag gctttagcag cgtagtttcc taagtgcaag agctctttct
    16021 tagcatttcc tagagcgata gatggggcct gtttgatgaa atgttcatca agatataagg
    16081 gttcgtattt gacaacctcg tcctctccag gaataatctt ggttacaaag taagccagag
    16141 ctccgataaa tggaaattgg acaatggtgt tggtaatatt aaaggttccg tgagcaaagg
    16201 cgatggtcat ttccggtgct agatttagcg tagcttcaaa ccaatgaatc aggacagtaa
    16261 aaggaactag aaaaataacg cagacgactg ttccgataac gttgaaggca acatgagctc
    16321 ctgctacccg tttagctgca atattagccc ctaaagaggc aatgatggct gtaatggtta
    16381 tcccgatatt gtcaccaaat agaactggca aagctccctg taggtcaatt agattgccgg
    16441 cgtagaggtt ttgtaaaatc ccaatggtag ccgaagaagc ttgaattagc aaggtcaagc
    16501 cggtaccgac aaagacaccc aaaacaggat tcttacttag ctcaatcata tagtccttaa
    16561 agacctgtaa atccttgagt ggagccattg cgccgctcat gagattgagg gcaaaaaaga
    16621 taccaccgac accaaagagg atgcgtccga tattattgac tgtccgattt tttgtaaaaa
    16681 agagacagac ggcaccgata aagagcatag gtagggcata gttacctaat ttaaaaccga
    16741 tgagaaagga tgtgacagtt gtcccaatat tagcacccat gacaatcccg atagcctgac
    16801 gtaaggttaa gagaccggca ctgaccaggc cgactgtgat aactgttaca ccagaactag
    16861 actgaattag agcagtcatc ccaataccaa ccagaactcc aaagaaagga ttactagtat
    16921 atttgtcaat gtaaaaacga aggcgatctc cagcagcttg ttgcaaaccg tctcccatgg
    16981 tcttgatgct atataagaat agccccagac cacctaaaaa gtgaaataaa atttcctgcc
    17041 aattaatgga catttctttt tcctccgaaa aataatcgcg gaatatcttc tattctattt
    17101 taaaggataa aagtaaatct aacaagtgtt aatgtcaagt ttgtaaaaga aaattataat
    17161 tgataagtgt attattttta agagttttta accttatttt agatttgtgc aaacagttat
    17221 tgttttttgt ctaaaaatgt tttaggataa aaatgtgatt atcatggttc tagagtttga
    17281 taaaaaacta cagaatataa agcgctttct tgaaaacaac aaaatcaatc ttttaggagg
    17341 agaaaatgaa gaatccattt tttgaaagac gttgtcgtta cagtattcgt aagttatcag
    17401 taggagcctg ctcgctgatg attggtgctg ttttatttgc tggtccagcc ttggctgaag
    17461 aaactgcagt tcctgaaaat agcggagcta atacagagct tgtttcagga gagagtgagc
    17521 attcgaccaa tgaagctgat aagcagaatg aaggggaaca tgctagagaa aacaagctag
    17581 aaaaggcaga aggagtagcg atagcatctg aaactgcttc gccagcaagc aatgaagctg
    17641 caactactga aactgcagaa gcagctagcg cagctaaacc agaggaaaaa gcaagtgagg
    17701 tggttgcaga aacaccatct gcagaagcaa aacctaagtc tgacaaggaa acagaagcaa
    17761 agcccgaagc aactaaccaa ggggatgagt ctaaaccagc agcagaagct aataagactg
    17821 aaaaagaagt ccagccagat gtccctaaaa atacagaaaa aacattaaaa ccaaaggaaa
    17881 tcaaatttaa ttcatgggaa gaattgttaa aatgggaacc aggtgctcgt gaagatgatg
    17941 ctattaaccg cggatctgtt gtcctcgctt cacgtcggac aggtcattta gtcaatgaaa
    18001 aagctagcaa ggaagcaaaa gttcaagcct tatcaaacac caattctaaa gcaaaagacc
    18061 atgcttctgt tggtggagaa gagttcaagg cctatgcttt tgactattgg caatatctag
    18121 attcaatggt cttctgggaa ggtctcgtac caactcctga cgttattgat gcaggtcacc
    18181 gtaacggggt tcctgtatac ggtacactct tcttcaactg gtctaatagt attgcagatc
    18241 aagaaagatt tgctgaagct ttgaagcaag acgcagatgg tagcttccca attgcccgta
    18301 aattggtaga catggccaag tattatggct atgatggcta tttcatcaac caagaaacaa
    18361 ctggagattt ggttaaacct cttggagaaa agatgcgcca gtttatgctc tatagcaagg
    18421 aatatgctgc taaggtaaac catccaatca agtattcttg gtacgatgcc atgacctata
    18481 actatggacg ttaccatcaa gatggtttgg gagaatacaa ctaccaattc atgcaaccag
    18541 aaggagataa ggttccggca gataacttct ttgctaactt taactgggat aaggctaaaa
    18601 atgattacac tattgcaact gccaactgga ttggtcgtaa tccttatgat gtatttgcag
    18661 gtttggaatt gcaacagggt ggttcctaca agacaaaggt taagtggaat gacattttag
    18721 acgaaaatgg gaaattgcgc ctttctcttg gtttatttgc cccagatacc attacaagtt
    18781 taggaaaaac tggtgaagat tatcataaaa atgaagatat cttctttaca ggttatcaag
    18841 gagaccctac tggccaaaaa ccaggtgaca aagattggta tggtattgct aacctagttg
    18901 cggaccgtac gccagcggta ggtaatactt ttactacttc ttttaataca ggtcatggta
    18961 aaaaatggtt cgtagatggt aaggtttcta aggattctga gtggaattat cgttcagtat
    19021 caggtgttct tccaacatgg cgctggtggc agacttcaac aggggaaaaa cttcgtgcag
    19081 aatatgattt tacagatgcc tataatggcg gaaattccct taaattctct ggtgatgtag
    19141 ccggtaagac agatcaggat gtgagacttt attctactaa gttagaagta actgagaaga
    19201 ccaaacttcg tgttgcccac aagggaggaa aaggttctaa agtttatatg gcattctcta
    19261 caactccaga ctacaaattc gatgatgcag atgcatggaa agagctaacc ctttctgaca
    19321 actggacaaa tgaagaattt gatctcagct cactagcagg taaaaccatc tatgcagtca
    19381 aactattttt cgagcatgaa ggtgctgtaa aagattatca gttcaacctc ggacaattaa
    19441 ctatctcgga caatcaccaa gagccacaat cgccgacaag cttttctgta gtgaaacaat
    19501 ctcttaaaaa tgcccaagaa gcggaagcag ttgtgcaatt taaaggcaac aaggatgcag
    19561 atttctatga agtttatgaa aaagatggag acagctggaa attactaact ggctcatctt
    19621 ctacaactat ttatctacca aaagttagcc gctcagcaag tgctcagggt acaactcaag
    19681 aactgaaggt tgtagcagtc ggtaaaaatg gagttcgttc agaagctgca accacaacct
    19741 ttgattgggg tatgactgta aaagatacca gcctaccaaa accactagct gaaaatatcg
    19801 ttccaggtgc aacagttatt gatagtactt tccctaagac tgaaggtgga gaaggtattg
    19861 aaggtatgtt gaacggtacc attactagct tgtcagataa atggtcttca gctcagttga
    19921 gtggtagtgt ggatattcgt ttgaccaagc cacgtaccgt tgttagatgg gtcatggatc
    19981 atgcaggagc tggtggtgag tctgttaacg atggcttgat gaacactaaa gactttgacc
    20041 tttattataa agatgcagat ggtgagtgga agctagctaa ggaagtccgt ggtaacaaag
    20101 cacacgtgac agatatcact cttgataaac caatcactgc tcaagactgg cgcttgaatg
    20161 ttgtcacttc tgacaatgga actccatgga aggctattcg tatctataac tggaaaatgt
    20221 atgaaaagct tgatactgag agtgtcaata ttccgatggc caaggctgca gcccgttctc
    20281 taggcaataa caaggtacaa gttggctttg cagatgtacc ggctggagca actattaccg
    20341 tttatgataa tccaaattct caaactccgc tcgcaacctt gaagagcgaa gttggaggag
    20401 acctagcaag tgcaccattg gatttgacaa atcaatctgg tcttctttat tatcgtaccc
    20461 agttgccagg caaggaaatt agtaatgtcc tagcagtttc cgttccaaaa gatgacagaa
    20521 gaatcaagtc agtcagccta gaaacaggac ctaagaaaac aagctacgcc gaaggggagg
    20581 atttggacct tagaggtggt gttcttcgag ttcagtatga aggaggaact gaggacgaac
    20641 tcattcgcct aactcacgca ggtgtatcag tatcaggttt tgatacgcat cataagggag
    20701 aacagaatct tactctccaa tatttgggac aaccagtaaa tgctaatttg tcagtgactg
    20761 tcactggcca agatgaagca agtccgaaaa ctattttggg aattgaagta agtcaggaac
    20821 cgaaaaaaga ttacctagtt ggtgatagct tagacttgtc tgaaggacgc tttgcagtgg
    20881 cttatagcaa tgacaccatg gaagaacatt cctttactga tgagggagtt gaaatttctg
    20941 gttacgatgc tcaaaagact ggtcgtcaaa ccttgacgct tcgttaccaa ggtcatgaag
    21001 tcaactttga tgttttggta tctccaaaag cagcattgaa cgatgagtac ctcaaacaaa
    21061 aattagcaga ggttgaagct gctaagaaca aggtggtcta taactttgct tcaccagaag
    21121 taaaagaagc tttcttgaaa gcaattgaag cggccgaaca agtgttgaaa gaccatgaaa
    21181 ctagcaccca agatcaagtc aatgaccgac ttaataaatt gacagaagct cataaagctc
    21241 tgaatggtca agagaaattt aaggaagaaa agacagagct tgatcgttta acaggtgagg
    21301 ttcaagaact cttggctgcc aaaccaaacc atccttcagg ttctgcccta gctccgcttc
    21361 ttgagaaaaa caaggccttg gttgaaaaag tagatttgag tccagaagag cttgcaacag
    21421 cgaaacagag tctaaaagat ctggttgctt tattgaaaga agacaagcca gcagtctttt
    21481 ctgatagtaa aacaggtgtt gaagtacact tctcaaataa agagaagact gtcatcaagg
    21541 gtttgaaagt agagcgtgtt caagcaagtg ctgaagagaa gaaatacttt gctggagaag
    21601 atgctcatgt ctttgaaata gaaggtttgg atgaaaaagg tcaagatgtt gatctctctt
    21661 acgcttctat tgtgaaaatc ccaattgaaa aagataagaa agttaagaaa gtatttttct
    21721 tacctgaagg caaagaggca gtagaattgg cttttgaaca aacggatagt catgttatct
    21781 ttacagcacc acactttact cattatgcct ttgtttatga atctgctgaa aaaccacaac
    21841 ctgctaaacc agcaccacaa aacaaagtcc ttccaaaacc tacttatcaa ccggcttctg
    21901 atcaacaaaa ggctcctaaa ttggaagttc aagaggaaaa ggttgccttt catcgtcaag
    21961 agcatgaaaa tgctgagatg ctagttgggg aacaacgagt catcatacag ggacgagatg
    22021 gactgttaag acatgtcttt gaagttgatg aaaacggtca gcgtcgtctt cgttcaacag
    22081 aagtcatcca agaagcgatt ccagaaattg ttgaaattgg aacaaaagta aaaacagtac
    22141 cagcagtagt agctacacag gaaaaaccag ctcaaaatac agcagttaaa tcagaagaag
    22201 caagcaaaca attgccaaat acaggaacag ctgatgctaa tgaagcccta atagcagtct
    22261 tagccagcct tggtcttgct agtttagcct tgaccttgag acggaaaaga gaagataaag
    22321 attaaatatc gaaaaatctt gtgaaatctt tccttatatt tccaaagtgt gatataatag
    22381 tttcgaataa aataaataaa ggagtttttg taacatggca aaacttactg ttaaagacgt
    22441 tgacttgaaa ggtaaaaaag tcctcgttcg tgttgacttc aacgtaccat tgaaagatgg
    22501 cgtaatcact aacgataacc gtatcacagc agctcttcca actattaagt acatcatcga
    22561 acaaggtgga cgtgcaattc ttttctctca ccttggacgt gtgaaagaag aagctgataa
    22621 agctggcaaa tcacttgctc ctgtagcagc tgacttggca gcaaaacttg gtcaagatgt
    22681 tgttttccca ggtgtcactc gtggtgctga attggaagcg gcaatcaacg ctcttgaaga
    22741 tggacaagtt ctcttggttg aaaacactcg ttacgaagat gttgacggca agaaagaatc
    22801 taaaaacgat cctgaacttg gtaaatactg ggcatcactt ggagatggta tcttcgtaaa
    22861 cgatgcattc ggtacagctc accgtgcaca cgcatctaac gttggtatct cagcaaacgt
    22921 tgaaaaagca gttgctggtt tccttcttga aaacgaaatt gcctacatcc aagaagcagt
    22981 tgaaactcca gaacgtccat tcgtggctat ccttggtggt tcaaaagttt cagacaagat
    23041 cggtgttatc gaaaacttgc ttgaaaaagc tgataaagtc cttatcggtg gtgggatgac
    23101 ttacacattc tacaaagcac aaggtatcga aatcggtaac tcacttgtag aagaagacaa
    23161 attggatgtt gcgaaagctc ttcttgaaaa agcaaatggt aaattgatct tgccagttga
    23221 ctcaaaagaa gctaacgcat ttgctggtta cactgaagtg cgtgacactg aaggtgaagc
    23281 agtttctgaa ggcttccttg gtcttgacat cggtccaaaa tctatcgcca aatttgacga
    23341 agctttgact ggtgccaaaa cagttgtatg gaacggacct atgggtgtat ttgaaaaccc
    23401 agatttccaa gctggtacaa tcggtgtgat ggacgctatc gtgaaacaac caggagttaa
    23461 atcaatcatc ggtggtggtg actcagctgc cgcagcgatt aaccttggcc gtgcagacaa
    23521 gttctcatgg attagtacgg gtggtggagc atcaatggaa cttcttgaag gtaaggttct
    23581 tccaggactt gcagccttga cagaaaaata agattttata aacaaatcaa agaagagagg
    23641 gatgaaagtt cctcttttct tttgcttaaa ataaaaacgc ttcctctcaa ctattactca
    23701 taaaaatcac cgatttatga taaaatggaa atagaaagtt gagattatga gttattttaa
    23761 aaaatataaa ttcgataaat cccagttcaa acttggtatg cgaaccttta aaacaggtat
    23821 tgctgttttt ctagttctct tgatttttgg cttttttggc tggaaaggtc ttcaaattgg
    23881 tgctttgaca gccgttttta gcctgaggga gagttttgat gagagtgttc attttgggac
    23941 ttcgcgtatt ctaggaaata gtatcggtgg actctatgcc ttggtcttct tcttattaaa
    24001 tacttttttc cacgaagcct tttgggtgac cttggtagtt gttccaatct gcaccatgtt
    24061 aaccattatg acaaatgtag ccatgaataa caaagcaggg gttattggtg gtgtagcagc
    24121 tatgttaatc attaccctat caattccaag tggtgagaca attttgtacg tgtttgtgcg
    24181 tgtattagaa acgtttatgg gagtttttgt cgcaattatc gtaaattacg atattgatcg
    24241 tattcgtctc tttttagaga aaaaagaaaa ataatgttac attttataac attatcaatt
    24301 gacgtttgtc tttttttaga ctataataga cagaaagaag gaaattgtaa atgaaggaaa
    24361 aagaatttcg ccgaaatatg gctgtttttc ctatcggcag tgttatgaag ttgaccgatt
    24421 tatcggcgcg tcagattcgt tattatgaag atcaagagtt gatcaagccc gatcgaaacg
    24481 aaggaaatcg tcgcatgtat tccttgaatg acatggatcg tctgcttgaa atcaaagatt
    24541 atatctctga aggttataat atcgctgcca ttaagaaaaa atatgctgaa cgtgaagcga
    24601 aatccaagaa agcggttagt cagactgaag tacgtcgtgc acttcacaat gaactcctcc
    24661 aacaggggcg ttttgcttca gtacagtcac cttttggtcg cggttaggca accgcaagta
    24721 gtcatagatt aaggagaaaa cttatgccaa tcacagctgc agatattcgt cgtgaagtca
    24781 aggaaaaaaa tgttaccttt attcgtctta tgttctcaga tattttggga accatgaaaa
    24841 acgtcgaaat tcctgctaca gatgaacagt tagataaggt cttgtcgaac aaggttatgt
    24901 ttgatggatc ttctattgaa ggttttgtac gtatcaatga gtcggatatg tacttgtacc
    24961 cggacttgga tacatggaca gtcttccctt ggggagatga aaatggaagt gttgcaggtc
    25021 tgatctgtga tgtctataca acagaaggtg aaccatttgc gggtgaccct cgtggtaatt
    25081 tgaaacgagc tcttcgtcac atggaagaag ttggattcaa atccttcaac cttggtccag
    25141 agccagaatt cttcctattt aagttggatg aaaatgggga cccaacactt gaagtgaatg
    25201 acaagggtgg ctactttgat ttggcaccta ctgaccttgc ggacaacaca cgtcgtgaga
    25261 ttgtgaatgt cttgaccaaa atgggatttg aagtagaagc gagtcaccac gaggttgcgg
    25321 ttggacagca tgagattgac tttaagtacg atgaagttct ccgtgcttgt gataagattc
    25381 aaatctttaa gcttgttgtt aaaaccattg ctcgcaaaca cggactttac gcaacattta
    25441 tggcgaagcc aaaatttggt attgctggat caggtatgca ctgtaatatg tccttgtttg
    25501 atgcagaagg aaataacgcc ttctttgatc caaatgatcc aaaaggaatg cagttgtcag
    25561 aaacagctta ccatttccta ggcggtttga tcaagcatgc ttacaactat actgccatca
    25621 tgaacccaac agttaactca tacaaacgtt tggttccagg ttatgaagcg cctgtttaca
    25681 ttgcttgggc tggtcgtaac cgttcgccac ttgtgcgcgt acctgcttca cgtggtatgg
    25741 gaactcgtct tgagttgcgt tcagtggatc caatggcgaa cccttacatt gctatggctg
    25801 ttcttttgga agttggtttg tatggtattg aaaataaaat cgaagcacca gctcctatcg
    25861 aagaaaatat ctacatcatg acagcagaag agcgcaagga agctggtatt acagaccttc
    25921 catcaactct tcacaacgct ttgaaagctt tgacagaaga tgaagtggtt aaagctgctc
    25981 tcggagatca catctacact agcttccttg aagccaaacg aatcgaatgg gcaagttatg
    26041 caaccttcgt ttcacaatgg gaaattgata attatttaga cctttactaa tactaatata
    26101 gaagaaagat tgcctgtggg taaacagtca cacagcagtc taagccatca aatacctata
    26161 acccttaaaa tagcgatttc ggtcgctatt tatttttcga aaaatcctct tgactctttt
    26221 gcgaattaga tttatcatca gacgtgtaga agaaaatcaa ggagtcacta tggaaaaatt
    26281 caatttcaaa aacaatatcg ggcaagaaaa caagttactt caaatcgaaa tctacaagtt
    26341 tactaacttt tgcaagcttc aaaattacac atctgtaaat attttttcga aagatatatt
    26401 tgaagccata gtaaattgag actagaatag tacactacat ctgctaaaaa tttctagaaa
    26461 ttaatttaac tttcctaatc gatttgttta catcttattt caatctacta tattatctca
    26521 ataaatgatg atggcgactg ttttgtttgt gcttgtcgat ttttgaatcc tgatcgagcg
    26581 gaagaatatt tctgccgagg ttgtcaaggg gaaaatcctg aagatattga attttatgat
    26641 gaacaattac aggcagaaaa ggtggaggct ttgaatattc gattggaagt aaaaaattga
    26701 attatctaca atctcatcaa caataaacct atttcaaccc cattatctat aggcgtattt
    26761 ttacgccttt ttatatactt gaagcacata agaaacatta tgggaagttt gctgatggaa
    26821 gtactcaaga aattgatgtt ccttatgata ttcctgatac ttgggagtgg gtgaggataa
    26881 aatcaattta ttggaatttt gggcaaaata agccagagaa atcctttagg tatatagata
    26941 cgtctagtat tgatagaaaa aagaacataa tcaactacaa aaatctacaa tatctttcac
    27001 ctgaacaagc gccttcccgt gccagaaaat tagtttcgca gaatagtgtc ttattttcaa
    27061 cagttagacc atatctaaaa aatattgctg tagttagaga acttaaagag tatttgatag
    27121 ctagtacagc atttattgtt ttggatactt tacttaacga aacatatttg aaatattatt
    27181 tattatcaga taattttatc aatcgtgtta ataataaatc tactggaaca agttatcctg
    27241 caatcaatga ttataatttt aatctattat taatt
//
LOCUS       DAVBCA010000027        25336 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.027, whole genome shotgun sequence.
ACCESSION   DAVBCA010000027 DAVBCA010000000
VERSION     DAVBCA010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25336)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25336)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25336
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.027"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..309)
                     /locus_tag="VQU19_001074"
     CDS             complement(<1..309)
                     /locus_tag="VQU19_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter substrate-binding protein"
                     /protein_id="HET2480330.1"
                     /translation="MKKKWMYYAACSSNESADDSSSDKGDGGSLVVYSPNSEGLIGAT
                     IPAFEEKYGIKIELIQAGTGELFKKLESEKEVPVADIIFGGSYTQYATHGELFENYIS
                     K"
     gene            complement(897..1673)
                     /locus_tag="VQU19_001075"
     CDS             complement(897..1673)
                     /locus_tag="VQU19_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HET2480331.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGINALHPEDLIDYQKVFLNHHINCYF"
     gene            1795..2541
                     /locus_tag="VQU19_001076"
     CDS             1795..2541
                     /locus_tag="VQU19_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET2480332.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     HQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            2554..3534
                     /locus_tag="VQU19_001077"
     CDS             2554..3534
                     /locus_tag="VQU19_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HET2480333.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            3729..4049
                     /locus_tag="VQU19_001078"
     CDS             3729..4049
                     /locus_tag="VQU19_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET2480334.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            4095..4403
                     /locus_tag="VQU19_001079"
     CDS             4095..4403
                     /locus_tag="VQU19_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET2480335.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQSSGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            4420..5718
                     /locus_tag="VQU19_001080"
     CDS             4420..5718
                     /locus_tag="VQU19_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET2480336.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASANLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQTLGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVITQLVILAMSTLVYFPFFKVQDRLAYQNEIKQS"
     gene            5869..8307
                     /locus_tag="VQU19_001081"
     CDS             5869..8307
                     /locus_tag="VQU19_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HET2480337.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMTIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            8326..8994
                     /locus_tag="VQU19_001082"
     CDS             8326..8994
                     /locus_tag="VQU19_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HET2480338.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHEIRRQAGDDIFIKVPVTPAGLRAIKVLK
                     KEGYHITATAIYTVIQGLLAIEVGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVTQN
                     SRSI"
     gene            9012..10100
                     /locus_tag="VQU19_001083"
     CDS             9012..10100
                     /locus_tag="VQU19_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HET2480339.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNYPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            10555..13056
                     /locus_tag="VQU19_001084"
     CDS             10555..13056
                     /locus_tag="VQU19_001084"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HET2480340.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSTEQ
                     AEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEIPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVAWLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLIRSKEIVAENNGALD
                     KVYNETVKAVTEQIDSLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAATGESISYVTWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKAEIDGKEIVKVISVPNKLVNIVVK"
     gene            13250..13945
                     /locus_tag="VQU19_001085"
     CDS             13250..13945
                     /locus_tag="VQU19_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2480341.1"
                     /translation="MPVNEYGQMIGESMEGYTPGELPSIDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPQEMWTYLFQEPVADMGELVSLLHQMLARKDRFYYAIIDKATGKALG
                     SFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYVFEELNYRRYEWKCDAL
                     NLPSRRAAERLSFIYEGTFRQAVVYKGRTRDTDWLSMIDKDWPQVKDRLETWLRPENF
                     DKNGQQYESLREL"
     gene            13957..14373
                     /locus_tag="VQU19_001086"
     CDS             13957..14373
                     /locus_tag="VQU19_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2480342.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEQALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVLVQDLIVLPIYQRQGIGSALMKEALEDYKDAYQVQ
                     LVTEETERTLGFYRSMGFEILSTYNCIGMTWMNRKK"
     gene            complement(15000..15092)
                     /locus_tag="VQU19_001087"
     CDS             complement(15000..15092)
                     /locus_tag="VQU19_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HET2480343.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            15253..16224
                     /gene="ruvB"
                     /locus_tag="VQU19_001088"
     CDS             15253..16224
                     /gene="ruvB"
                     /locus_tag="VQU19_001088"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HET2480344.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            16205..16777
                     /locus_tag="VQU19_001089"
     CDS             16205..16777
                     /locus_tag="VQU19_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HET2480345.1"
                     /translation="MNTVKNKQEILEAFRENPDMMAILTIIRDLGLKDSWLAAGSVRN
                     FIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLEKKLREDFPQYQWELKNQVYMHQ
                     HSPHTASYTSSRDAMSKYPERCTAVGLRLNEESDFELYAPYGLEDILNFQVRPTPHFL
                     ENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            17008..17766
                     /locus_tag="VQU19_001090"
     CDS             17008..17766
                     /locus_tag="VQU19_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HET2480346.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            17775..18578
                     /locus_tag="VQU19_001091"
     CDS             17775..18578
                     /locus_tag="VQU19_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HET2480347.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            18600..19859
                     /gene="rseP"
                     /locus_tag="VQU19_001092"
     CDS             18600..19859
                     /gene="rseP"
                     /locus_tag="VQU19_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HET2480348.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            19872..21725
                     /locus_tag="VQU19_001093"
     CDS             19872..21725
                     /locus_tag="VQU19_001093"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HET2480349.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            21825..23204
                     /gene="bglA"
                     /locus_tag="VQU19_001094"
     CDS             21825..23204
                     /gene="bglA"
                     /locus_tag="VQU19_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HET2480350.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTVFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNELIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIHDNTVDFLGVNYYQPLRVMAPRFAKHPESPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KKLSDNNGF"
     gene            23396..25204
                     /gene="glmS"
                     /locus_tag="VQU19_001095"
     CDS             23396..25204
                     /gene="glmS"
                     /locus_tag="VQU19_001095"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HET2480351.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEDGLSVLEAFKKALHIIRGSYAFAL
                     IDSENPDVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNRRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDEAGQ
                     VVVDPDIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
BASE COUNT         7735 a         4313 c         5537 g         7751 t
ORIGIN      
        1 ttttgaaata tagttttcaa agagttctcc gtgggtagca tattgtgtat aagaaccacc
       61 aaagataata tcagctacag gaacttcttt ttctgactct agttttttga aaagttctcc
      121 agtaccagct tgaatcagtt ctattttgat accatatttt tcttcaaagg caggaatagt
      181 tgctccaatt aagccttctg agtttggtga ataaacgact agcgaaccac cgtctccttt
      241 atcagatgaa ctgtcatcgg cagattcatt agaagaacaa gcagcataat acatccattt
      301 ctttttcatg atggatacct ccgttgtgtt atttaagttt attttaaaac aatgtaagcg
      361 tttttaaaac ctacaattct attctatagt gtattgaatc tataacagta cacattgact
      421 gctaaaatat ttctataaat taatttgact ttcctgatag agatgttcac atcttatttc
      481 aattcactat attagagtaa aattctctac aaaaaaaaag aatagcctat tttactattt
      541 ttccgagtga tttcaattcc tttggggaaa tatggagata ctttttaaat cctgacaaat
      601 ggttgtttct ttttctaaat cggtgatact gtatcggaga atgcgcgtga ggtcacaaag
      661 gctgcgatag agcttctatg gagaatttct ttttggagag attttttaaa ggaatgagac
      721 atccgctacc tccttggaag gtttttttgt gataagtata gcagtttaaa aattctagag
      781 caaggtaaaa tagaaaaggt ttggctaaaa ttttttagct aaaccttttg aaaagttaag
      841 tatgtattat agatgcttgt tatctgcaaa tagctagagc atttcaagga aataaactag
      901 aaataacaat taatatggtg gttcagaaat accttttgat aatcaataag atcttcagga
      961 tgaagtgcgt tgattccatc catttcatat ttccgattta ataaacgata tttgttttca
     1021 ccaaattgat gaaaagggag tagttgaact tggtcgatat ttaatgagtt aaatagagta
     1081 gcgaattttt ctgcatcctc taaactattg ttaaaattag gaataactgg gattcttaaa
     1141 acgatagttt tattttgtga aaaagcataa tgaatgtttt taataatcat ttgattaaaa
     1201 accccagtca cttttttatg ttttatagaa ttataatgtt ttaggtctgt gtagataaaa
     1261 tccacatatt gaattaaatc aataaatttt tcatgatcaa caaaggcagt agtttcaatg
     1321 gcagtgtgta tgtgatgttc tttagctgat tttaagatag ctttagcaaa ttcaaactga
     1381 gcaaatattt cacctcctga taaagttaaa cctccaccgg attcttcgta aaattctttg
     1441 tcttttaata cctctgtaat aatttcttct acagtctttt cttcaccgac taaggtgaat
     1501 ttctctcgtt gagcatcttt cattttttca ggtttcattc tttgagattc aggattagaa
     1561 caccatggac agcgcagagg acatcctttt aaaaaaacag ttgtacgaat acccgggccg
     1621 tcatgaattg aaaagtgttg aatattaaaa ataattcctt tagatatttc cataagagtt
     1681 cctcctcttc ataagtctat cctatcacaa aaacgaaaga aaaacaatta cgaacgaaag
     1741 gttaatttgt tgttttttgc tttttatttt ggtagaataa aacggaggtg taaaatgaaa
     1801 agattggaac aaattattaa attagtatca gaatatgaaa agatcgacgt taatacatta
     1861 tcggaaaaat taaatgtatc gaaagtaacg attagaaaag atttagataa attagagtca
     1921 aaaggtttat tacacagaga gcatggatat gctgtattaa atagtggaga tgacttaaat
     1981 gtacgtttgt caattaatta tgaaattaag agaaaaattg ttcaggaagc agtaaaattg
     2041 gtgtcagata atgaaacgat aatgatagaa tctggatcga cctgtgcttt acttgctgag
     2101 gaaatttgca agcaaaaaag aaatgttacg attgtaacaa attcattttt tatagcaaat
     2161 tttgtgagag cttatgattc atgtcgtatt attgttcttg gtggagagtt tcagaaggat
     2221 tcacaggtta ctgtgggacc tttattaaaa gaaatgatac agacttttca tgtgcatcaa
     2281 gcttttgttg ggacagatgg atacgataaa gagatgggct ttacaggaaa agatttaatg
     2341 cgcagtgagg tagttcaata tatttcagca gcgtcggata aagtcattgt cctaactgac
     2401 tcaagtaaat ttgataaaag gggtacagta agaagatttg ctttaagtca agtctatgaa
     2461 gtaataacag acgaaaaact ttctaaacaa aatatagcta cattagaaaa tgctgggata
     2521 atggttaagg tagtttcgta agaggttaag tgtatgaatc aagataggaa taaactgctc
     2581 tctaaaattg cttatctgta ttatattgaa aacttaaatc agtcacaaat agcagcaaaa
     2641 ttaggaattt atagaacctc tattagtaga atgttaacag aagcaaggaa tgcaggaatt
     2701 gttaaaattg aaatagagaa ttttgatacc aatatgttta agttggaaaa ttatgtaaaa
     2761 gaaaaatatg gtctggaaag tttagaaatt attccaaatg aatttgatga taatccaaca
     2821 attttatctg aaagaatttc tcaagttgca gcaggtgtcc ttaggaatct aattgatgat
     2881 aatatgaaaa ttggcttttc ttgggggaaa agtttaagta atttagtaga tttaattcac
     2941 agtaaaagtg tccgaaatgt tcacttctat cctctagcag gtggtcctag tcacatacac
     3001 gctaaatacc atgtgaatac actgatttat gaaatgtcta gaaaatttca tggagagtgt
     3061 acatttatga atgcaacgat tgtgcaagaa aataaattgt tagcagatgg tattttgcaa
     3121 tcaagatatt ttgaaaattt gaaaaatagt tggaaagatt tagatatagc tgtagtcgga
     3181 attggtgatt ttagcaataa aggaaagcat caatggttag acatgcttac agaggatgac
     3241 tttaaagaat tgaccaaagt taaaactgta ggagaaattt gttgtcgatt ttttgattca
     3301 aaaggtaaag aagtctatga aaacttacag gaaagaacga tagcaatctc tttggaagat
     3361 ttaaaaaata ttcctcaaag tttagctgtt gcttacggtg atacgaaagt atcttcgatt
     3421 ctttctgtct tgcgtgctaa tttagtaaat catttgatta cagacaaaaa tacaatttta
     3481 aaagttttgg aagaagatgg ggatttgact tttagagaga ttctaggtga gtgaaaatga
     3541 tagactgatt cagtttatcg tttttctttt tagttgattg cacatttgtg cttatataaa
     3601 caaaaatagt ttatctgttg tttttggatt gacaacttta ttatgtagtt gtattctata
     3661 gttacaaaag aaaattttaa aatttcaaat gaaaaaagct ttttacatag tgaaatgagg
     3721 aggaatttat ggaaattatt gttccagatc aaattatcat gggtttaatt ttatatgctg
     3781 gtgatgcgaa acaacatatt tataaagcgt tagattacat aaaaaatggt acatgtgaac
     3841 ggtgtgaaga agaaatccag ttagctgatg ccgccttatt agaagcccat aatctacaaa
     3901 caaaattctt ggcacaagaa gcgtctggta caaagacaga aattacagct ctctttgttc
     3961 attcacaaga tcatctcatg actagtatga cggagattaa tttaatcaaa gaaattatta
     4021 gtttgagaaa agaacttcat aaaaaataat actagagtat tatcattgtt attaacatag
     4081 aggaggaaaa cataatggtg aagattggtt tgttttgtgc agcaggtttt tctactggta
     4141 tgcttgtaaa taatatgaaa attgcagcgc aatctagtgg agttgaggca gaaatagagg
     4201 cgttttctca gtctaaatta gcggattatg cgccaaatat agatgttgca ctattgggtc
     4261 cacaagttgc ttatacatta gataaatcaa aagaaatttg tgataagtgt gatgttccga
     4321 tagctgttat tccgatgatg gactatggta tgttagatgg gaaaaaagta ttagatttgg
     4381 ccctatcttt gattagtggg taagaaaagg agatttatta tgtcaaagat ggatgttcag
     4441 aaaatcattg caccgatgat gaagtttgtg aatatgcgtg gcattatagc tctaaaagat
     4501 gggatgttag caattttgcc attgacagta gttggtagtt tgttcttgat tatgggacaa
     4561 ttgccgttcg aaggattaaa taagagcatt gctagtgttt ttggagctaa ttggacagag
     4621 ccgtttatgc aagtatattc aggaactttt gctattatgg gtctaatttc ttgtttttca
     4681 attgcctatt cttatgctaa gaatagcgga gtagaggctt taccagctgg agttctatct
     4741 gtatctgcat tctttatttt gctaagatca tcttatatcc ctaaacaagg tgaggcgatt
     4801 ggggacgcta ttagtaaagt ttggtttgga ggccaaggaa ttatcggtgc tatcattata
     4861 ggtttggtag taggaagtat ttataccttc tttataaaga gaaaaattgt tattaagatg
     4921 ccagaacaag ttccacaagc tattgccaaa cagtttgaag caatgattcc agcatttgta
     4981 attttcttat cttctatgat tgtatatatt ttagcgaagt cattgactaa tggcggaaca
     5041 ttcatagaaa tgatttattc tgctattcaa gttccgttgc aaggtttaac tggatctttg
     5101 tatggtgcta ttggaattgc attctttata tcatttttgt ggtggtttgg tgttcatggg
     5161 caatcggtag taaatggagt agtgacagct ctgcttttat ctaatcttga cgctaataaa
     5221 gctatgttag cctctgctaa tctatcatta gaaaatggtg cacatattgt tactcaacaa
     5281 tttttagatt catttttaat tctatcaggt tcagggatta cgtttggtct tgtagttgcc
     5341 atgctttttg cagcaaaatc aaaacaatac caaaccttag gaaaagttgc agcttttcca
     5401 gcaatattta acgtaaatga gccagttgta tttggatttc cgattgtcat gaatccagtt
     5461 atgtttgtac ctttcattct tgttcctgta cttgcagctg tgatagtata tggagctatt
     5521 gcaacaggtt tcatgcagcc attctcaggg gtaacattgc cttggagtac accagctatt
     5581 ttatcaggat ttttggtggg tggatggcaa ggagttatta ctcagctggt gatattagcg
     5641 atgtctacat tggtttattt tccattcttt aaagtacagg atcgtttagc ttaccaaaat
     5701 gaaatcaaac aatcttagag gtatttgtgt gttactgtta aactcacaca tttgtgctaa
     5761 aaattagaga gttaaaattt ttctagttaa aagcttgaaa atttctataa aaatcggtat
     5821 tatattttcg aaagaaataa aaatattttc gaaagaaagg tggttacgat ggtaaataca
     5881 gaagtagcaa gaacaacaat caagacagaa tattttggca gccttactga aaggatgaac
     5941 aaatatcgag aagatgtttt aaataaaaaa ccttatattg atgctgagag agcagttcta
     6001 gcaacacgcg cctatgaacg atacaaggaa caacctaatg tcctaaaacg tgcatatatg
     6061 ctgaaagaaa ttttggaaaa tatgactatc tatattgaag aagaatctat gattgcggga
     6121 aatcaagctt cttccaataa agatgctcct atttttccgg aatatacgct agaatttgtt
     6181 ctcaatgagt tggatctttt tgaaaagcgt gatggagatg ttttctatat tacagaagaa
     6241 acaaaagaac aacttagaag tattgctccg ttttgggaaa ataataattt acgtgctaga
     6301 gctggtgcct tattacctga agaagtgtct gtttatatgg aaacaggatt cttcggtatg
     6361 gaaggtaaga tgaattctgg agatgctcac ctagcagtta actatcagaa acttttgcaa
     6421 tttggtttaa gaggttttga agagcgggct cgtaaagcaa aagtagctct agatttaaca
     6481 gatccagcaa gtattgataa atatcatttt tacgactcta tatttatcgt aatcgatgct
     6541 attaaagtat atgcaaagcg ctttgttgct cttgctaaaa gtttagccga aaatgcaaat
     6601 cctaaacgta agaaagaatt acttgagatt gcagatattt gctctagagt cccatatgaa
     6661 ccggcaacta cttttgcaga agctattcaa tcagtttggt ttattcaatg tattttacaa
     6721 attgaatcta atggccactc tctttcatat ggccgttttg atcaatatat gtatccatat
     6781 atgaaggctg atttagaaag tggtaaagaa acagaagata gcattgttga acgtctgaca
     6841 aatctttgga ttaagacaat tacaatcaat aaggttcgca gtcaatcaca tacattttct
     6901 tcagcaggaa gtcctttata tcaaaatgtt acaattggtg gacagactcg agataagaag
     6961 gatgctgtta acccattatc ttatttggta ttaaaatcag ttgcacaaac ccatctaccg
     7021 caacctaatc taactgtacg ttaccatgca ggtttagatg ctcgtttcat gaatgagtgt
     7081 attgaagtga tgaaacttgg ttttggtatg cctgcattta ataatgatga gattattatt
     7141 ccttctttta ttgcaaaagg agtattggaa gatgatgctt atgattacag tgccattgga
     7201 tgtgttgaaa cggcagttcc agggaaatgg ggctatcgtt gcacaggtat gagttatatg
     7261 aacttcccta aggttctact tatcacgatg aatgatggaa ttgatccggc ttcgggtaaa
     7321 cggtttgcac caagctttgg tcattttaag gatatgaaga acttttctga attagaaaat
     7381 gcttgggata aaacactaag atatttgaca cgaatgagtg ttattgttga aaattctatt
     7441 gatttatcat tggaacgaga agttcctgat attctatgtt cagcattgac tgatgattgt
     7501 attggtcgtg gaaaacacct taaagaaggt ggagcagtat atgattatat atcaggattg
     7561 caagttggaa ttgcaaattt gtcggattca ttagctgcaa ttaaaaaatt ggtgtttgag
     7621 gaagaacgta taagcccaag tcagctttgg catgcactgg aaacagatta tgccggagaa
     7681 gaaggtaagg tcattcaaga aatgttgatt catgatgcac ctaagtatgg taatgatgat
     7741 gattatgctg acaaattggt tactgctgct tatgacattt atgttgatga aattgctaaa
     7801 tatcctaata cacgttatgg aagagggcct attggaggaa ttcgttattc aggaacatct
     7861 tctatctcag ccaacgtagg gcagggacgt ggaacattag caactccaga tggacgcaac
     7921 gcgggtacac cgttagcaga gggttgttca ccatcacata atatggatca acacggccct
     7981 acatctgttt taaaatctgt ttcaaaatta ccaacagatg aaatcgtagg tggggttctc
     8041 ttaaatcaga aagtaaatcc tcaaacgtta gccaaagaag aagataaatt aaaactaatt
     8101 gctttgttac gaacattctt taatcgttta catgggtacc atattcaata caatgttgtt
     8161 tccagagaga cgttgattga cgctcagaaa catcctgaaa aacacagaga cttaattgtt
     8221 cgtgttgcag gatactctgc attcttcaat gttctttcta aggcaaccca agatgacatt
     8281 ataggacgta ctgagcatac tttgtaaaat aaagaggttc tttttatgga atttatgctt
     8341 gacacattaa atttagatga gattaaaaag tggtctgaaa ttttgccgct agctggggta
     8401 acttcaaatc ccactattgc aaaaagagag ggttctatta atttttttga acgaatcaaa
     8461 gatgtaagag aattgattgg ctctacaccc tctattcatg ttcaggtgat ttctcaagat
     8521 tttgaaggca tcttaaagga tgctcatgaa attcgaagac aagcaggaga tgatatattt
     8581 atcaaagtac ctgttactcc agctggatta cgtgcaataa aggtgctaaa aaaagagggc
     8641 taccatatca ctgcaacagc tatttataca gttattcagg gattattagc tatcgaagta
     8701 ggagcggatt acctagctcc atattataat agaatggaaa atctgaacat tgattcaaat
     8761 tctgtcattc gtcaattagc tcttgctatt gatagacaga actctcctag taagatttta
     8821 gctgcatcct ttaaaaatgt agcacaagta aataatgctt tagctgcagg tgcgcatgct
     8881 gttacagcag gagcagatgt ttttgaatca gctttcgcca tgccatctat ccaaaaggcg
     8941 gttgatgatt tttctgacga ttggtttgtt actcaaaata gtcgttccat ttagatagag
     9001 aggaaataca tatgagaatt tttgctagtc cttctagata tattcagggg gaaaatgcct
     9061 tgtttgaaaa tgccaaatca attttggatt tgggaaatta ccctattcta ttatgcgatc
     9121 agttggttta tgatattgtt ggaaaacgat ttgaagatta tctacatagg tatggtttcc
     9181 atattgttct ggcgctattt aatggtgaag cttctgacaa tgaaatcaat cgagttgttg
     9241 ccttggctga gaaagaaaat tgtgatagta ttatcggtct tggtggggga aagacgattg
     9301 atagcgcaaa agctattgca gatttgattg aaaagcctgt tattattgct ccaacaattg
     9361 catcgaccga cgcacctgta tctgctttat ctgttattta tacagatgaa ggtgcatttg
     9421 atcattatct attttattct aaaaatccag atttagtttt ggttgataca aaagttattt
     9481 cacaagcccc taagcgttta ttagcgtctg gtattgcaga tggtttagca acttgggttg
     9541 aggcgcgtgc ggttatgcag gcaaatggaa aaactatgtt gggacaacag caaacattgg
     9601 ctggagttgc aattgcgaag aaatgtgaag aaacgctgtt tgcagatggt ttacaggcta
     9661 tggcagcttg tgaagctaaa gtggtgacac cagcattaga aaatattgtt gaagctaata
     9721 ctttattgag tggcctaggt tttgaaagtg gaggattagc tgcggcgcat gcaattcata
     9781 atggttttac tgcattgaca ggtgacattc atcatttaac acatggtgaa aaagtagctt
     9841 atggaacttt agtacaacta ttattggaaa atagacctaa agaagaactt gataagtata
     9901 ttgagtttta caaaaaaatt ggtatgccaa caactctaaa agaaatgcat ttggatcaag
     9961 ttggatatga tgatttaata aaagttggta aacaagcaac tatggagggt gagacaattc
    10021 atcagatgcc gtttaagatt tcgccttcag atgttgctca agctattatc gctgtagatg
    10081 cctatgtaaa ttcaaaataa acaataagga ctactgtttt ccaaatggta gtcttttatt
    10141 gatcctcgta ttgaattcta tagcagattg aaataagatg agaacaaatc gattgggaaa
    10201 gtaaaattaa tttctataag tattttagca attgtttcgt actatttcag attcagtcca
    10261 ctatacgttc ttcataaatc aaaaagcgac ataggttgtc ggctatttat tgtgaataca
    10321 ttaattagca ttccagtttt atcttcggtc taaaataagt attttgtgct atacgagata
    10381 agtttcttga cttactcctt gatttactgc ataacaatgg gataaaaagt gggagataga
    10441 gcaattcata gtcatcaaaa ttaatgagat acagtataca gtttttcctt taaacacatt
    10501 tcaaattccc tcaaaaatgg tataatagta acatcacaaa attggagaga gaccatgagt
    10561 ttttacaatc ataaagaaat tgagcctaag tggcagggct actgggcaga acatcataca
    10621 tttaagacag gaacagatgc atcaaaacct aagttttatg cgcttgatat gttcccttat
    10681 ccgtctggag ctggtctgca cgtaggacac ccagaaggtt atactgcaac cgatatcctc
    10741 agtcgttaca aacgtgcgca aggctacaat gtccttcacc caatgggttg ggatgctttt
    10801 ggtttgcctg cagagcaata cgctatggat actggtaatg acccagcaga atttacagcg
    10861 gaaaacattg ccaacttcaa acgtcaaatc aatgcgcttg gattttctta tgactgggat
    10921 cgtgaagtca acacaacaga tccaaactac tacaagtgga ctcaatggat tttcaccaag
    10981 ctttacgaaa aaggcttggc ctatgaagct gaagtgccag taaactgggt tgaggaattg
    11041 ggaactgcca ttgccaatga agaagtgctt cctgacggaa cttctgaacg tggaggctat
    11101 ccagttgtcc gcaaaccaat gcgccaatgg atgctcaaaa tcacggctta cgcagagcgc
    11161 ttgctcaatg acttagatga actagattgg tcagagtcta tcaaggatat gcaacgcaac
    11221 tggattggta aatcaactgg tgccaatgta actttcaaag taaaaggaac agacaaggaa
    11281 tttacagtct ttactactcg tccggacaca cttttcggtg cgactttcac tgttttggct
    11341 cctgaacatg aattagtaga tgccatcaca agcacagagc aagcagaagc agtagcagac
    11401 tacaaacacc aagccagcct taagtcagac ttggctcgta ccgaccttgc caaagaaaaa
    11461 actggtgtat ggactggtgc ttatgccatc aatcctgtca atggtaagga aattccaatc
    11521 tggattgcgg attacgttct tgctagctat ggtacaggtg cggtaatggc tgtgcctgcc
    11581 cacgatcaac gtgactggga atttgccaaa caatttgacc ttccaatcgt cgaagtactt
    11641 gaaggtggaa atgttgaaga agctgcctac acagaagatg gccttcacgt taattcagac
    11701 ttcctagatg gactcaacaa agaagacgct attgccaaga ttgtggcttg gttggaagaa
    11761 aaaggctgtg gacaagagaa ggtaacctac cgtctccgcg actggctctt tagccgtcaa
    11821 cgttactggg gtgagccaat cccaatcatt cattgggaag atggaacttc aacagctgtc
    11881 cctgaaagtg aattgccact tgttttgcct gtaaccaagg atatccgtcc ctcaggtact
    11941 ggtgaaagtc cactagctaa cttgacagac tggcttgaag tgactcgtga agatggtgtc
    12001 aaaggtcgtc gtgaaacaaa tactatgcca caatgggcag gttcaagctg gtactacctc
    12061 cgctatattg acccacacaa tactgagaaa ttggctgacg aggatctgct caaacaatgg
    12121 ttgccagtag atatctacgt gggtggtgcg gaacatgctg tacttcactt gctttacgct
    12181 cgtttctggc ataaattcct ctatgacctc ggtgttgttc caactaagga accattccaa
    12241 aaactcttta accaaggaat gattttggga acaagctatc gtgaccaccg tggggctctt
    12301 gtggcgactg acaaggttga aaaacgtgat ggttctttct tccatgtgga aacaggggaa
    12361 gagttggagc aagcgccagc caagatgtct aaatcgctca agaacgttgt caacccagac
    12421 gatgtggtgg aacaatacgg tgctgatacc cttcgtgtct atgaaatgtt catgggacca
    12481 ctcgatgctt cgattgcttg gtcagaagaa ggtctggaag gaagtcgtaa gttccttgac
    12541 cgtgtttacc gtttgattag aagtaaggaa attgttgcgg aaaacaatgg cgctcttgac
    12601 aaggtttaca acgaaactgt taaagctgtc acagagcaaa ttgattccct caaattcaac
    12661 acagccattg cccaacttat ggtctttgtc aatgcggcta acaaggaaga caagctctat
    12721 gttgactatg ccaaaggatt tatccaattg attgccccat ttgcacctca cttggcagaa
    12781 gaactctggc aaactgttgc tgcaacaggt gagtcaatct cttacgtgac ttggccaaca
    12841 tgggacgaaa gtaaactggt tgaagacgaa atcgaaatcg ttgtccaaat caaaggtaaa
    12901 gtccgtgcca aactcatggt cgctaaagac ctatcacgtg aagaattgca agaaattgct
    12961 ctagcggatg aaaaagtcaa agcagaaatt gacggtaagg aaatcgtgaa agtgattagt
    13021 gtaccaaata aattggttaa tattgttgta aaataaccaa tttatttgct gatttccaac
    13081 ctcaaacagt ttcccaaact gtttgagcca actaaactcg ttaatatcgt tgtgaaataa
    13141 ggtaggaatc cttcagagta gaatctggag gattttttga atcttcttat gaaagtatgg
    13201 tatactatgg gcaactataa agtttgaaaa gtgaaaaaag gagaaagcta tgccagtaaa
    13261 tgaatatggt caaatgattg gggagtcaat ggaaggttat acaccaggtg aactgccttc
    13321 tattgatttc ttagaagggc gttatgctag gatagaggct ctttcagtgg aaaagcatgc
    13381 ggaggatttg ctagctgttt atgggcctga tacgcctcag gagatgtgga cctacctttt
    13441 tcaggagcca gtagcagata tgggggagct ggttagcctt ttacatcaga tgttggctcg
    13501 taaggaccgt ttttactatg caatcataga caaggcgact ggtaaggctt tgggatcttt
    13561 ttctctcatg cgcattgacc agaataaccg agtaatagaa gtcggagcag tcactttttc
    13621 tccagagcta aggggtacac ggataggaac tgaagctcag tatctcctag ctcgctatgt
    13681 ttttgaggag ctaaactatc gtcgctacga gtggaaatgc gatgccttaa atctgccatc
    13741 cagacgagct gcggagcgtt tgagctttat ttatgaagga accttccgtc aggcagtggt
    13801 ttataaggga cgtacgagag atacggattg gttgtctatg attgataagg actggcctca
    13861 agtcaaagat cgtttggaaa catggttgcg tcctgaaaat tttgataaaa atggacagca
    13921 gtacgagagc ttgagagaac tttaagaggt gttgagatga ttactattaa aaagcaagaa
    13981 attgtcaagc tagaggatgt tttacatctc tatcaggctg tcggttggac aaattatacc
    14041 catcaaccag agatgctgga gcaggcctta tctcattcat tagtaattta tctggcactt
    14101 gatggtgatg ctgtggtggg cttgattcgt ttggttggag atggattctc atcagtattg
    14161 gttcaggatt taatcgtttt accaatctat cagcgtcaag gaattggtag tgccttgatg
    14221 aaagaggctt tagaggatta caaagatgcc tatcaagtcc agctggtgac agaagagaca
    14281 gaaagaacct tgggcttcta tcgttctatg ggctttgaaa tcttatccac ctataattgt
    14341 atagggatga cttggatgaa tcgtaaaaaa taacaaaact tgttttttct taagcaaaat
    14401 ttaaggatgg tctagtatta tatagtcatt aaataaagac ctcctaactt tatttaataa
    14461 aatcctaaac ttttcttttt cataataatc tcccttaact ccacccaatc aggtggagtt
    14521 ttttagctct atttcaggct tttggggact attctaaaaa taatttttcg atatttttcg
    14581 gtatttttcg gattttggtc ggggaattgg cggggacttt tttagcgaat ataactaaga
    14641 aataggtctg tggtcgcttc agctagttca aactcaattt gattgtaagt gactgttaat
    14701 tgaagaactg gaactactgt aataatgatt ttgcttgtct agtagtggcg tattaaatga
    14761 gaagtgacat gtaagattgt ctcttcgttt acgaaatcaa aatttctatg aaattgatag
    14821 aatccctaac gttctcttaa tcttaaccgt cttgtcgtac agcggttgaa gaaaatgtaa
    14881 acctttgaca aaattcgtga actatgggat aataaaaagg aattgagtac tagttctata
    14941 tcataggcta gaaaagaccc caagctcacg accaaataag cttgaggtct tttttgacac
    15001 tatttgtcct tgtttagcca tttatcgact atacgaagaa cgacaccgac cacaattggt
    15061 ccgatgatag ttttgagtac taattccatc atgggctatc tcacctcctt tcgtaggcgg
    15121 tgtagcagtg tcgtagaata ttataccaca taagtgctaa acttaggagt cacccaatca
    15181 ggtggctttt ttgtttgtgg cttggttttt tgatataata gagccatgag tagaatttta
    15241 gataatgaga taatggggga tgaggagtta gtagaacgca cgctccgtcc tcagtattta
    15301 cgtgaatata tcggacagga taaggtcaag gaccagctac aaatctttat tgaagctgcc
    15361 aaaatgcggg atgaagcgct ggatcatgtg ctcttatttg ggcctccagg tctcgggaaa
    15421 acgaccatgg cctttgttat tgccaacgaa ctgggagtca atcttaagca gacgtcgggt
    15481 ccagtcattg aaaaagccgg agatctggta gctattttga atgagttaga gcctggggat
    15541 gtacttttta ttgatgagat ccatcgtttg ccaatgtcag tggaagaggt gctttatagt
    15601 gctatggagg acttctacat agatattatg attggggctg gtgagggtag tcgtagtgtt
    15661 catttggagt taccaccttt taccttgatt ggtgcgacga ctcgggctgg tatgctctcc
    15721 aatccgctac gggcacgttt tgggattaca ggccatatgg agtattatgc ccatgctgac
    15781 ttgacagaaa ttgtcgagcg gacggcagat atttttgaga tggaaatcac tcatgaggca
    15841 gcatctgagt tggccctacg tagtcgtggg acccctcgta ttgccaatcg tctcctcaag
    15901 cgcgtgcgcg attttgccca gataatgggg aatggggtaa ttgatgatat tattaccgat
    15961 aaggctttga ctatgctgga tgttgaccat gaaggtttgg actatgtgga tcaaaaaatc
    16021 cttcgtacca tgattgagat gtacagtgga ggacctgttg gtctaggaac tctttctgtg
    16081 aatatcgccg aagagcgtga gacagttgaa gatatgtatg agccttactt gattcaaaaa
    16141 ggttttatca tgcggacacg gtctggacgg gtggcgactg ctaaggcata tgagcactta
    16201 ggttatgaat acagtgaaaa ataagcaaga aatcttagag gcttttagag aaaatccaga
    16261 tatgatggcc attctgacga tcatccgaga ccttggtctg aaagactcgt ggttggcagc
    16321 aggttctgtc agaaatttca tttggaatct tttgtcagac aaatcccctt ttgatcatga
    16381 aacagatata gatgtgattt tctttgatcc agatttttct tatgaggaaa ccttattact
    16441 ggagaaaaag ctgagagagg attttcctca gtaccagtgg gaattgaaaa atcaggtcta
    16501 tatgcatcag cacagtcctc acactgcttc ctataccagt tctcgtgatg ctatgagtaa
    16561 gtatccagaa cggtgtacgg cagttggact gcgcttgaat gaagaatcag attttgaact
    16621 ctatgcacct tatggtttgg aggatatttt gaattttcaa gttcgtccaa ctcctcattt
    16681 cttagaaaat gaagaccgaa tggaactcta tcaaacacgt ttatccaaga aaaattggca
    16741 ggagaaatgg aaaaatttga tttttaaaaa tacttaagga aactttaagc tagggagtgt
    16801 acactaagtt cataagttaa gaagacctta acttaaactc ctaaaacttt ttcataataa
    16861 tctccctata aaaataaagt cgcccaatca ggcggcttat ttttttgaaa aatgggcatg
    16921 gtgcctgaga ataaatagct tagtgataga agaaaatggg gaaatatggt ataatgaaac
    16981 gatagatttt tgaataggaa taagatcatg tttggatttt ttaagaaaga taaggctgtg
    17041 gaagtagagg ttccgacaca ggttcctgct catatcggca tcatcatgga tggcaatggc
    17101 cgttgggcta aaaaacgtat gcaaccgcga gtttttggac ataaggcggg catggaagca
    17161 ttgcaaaccg tgaccaaggc agccaacaaa ctgggcgtca aggttattac ggtctatgct
    17221 ttttctacgg aaaactggac ccgtccagat caggaagtca agtttatcat gaacttgcca
    17281 gtagagtttt atgataatta tgtcccggaa ctacatgcga ataatgttaa gattcaaatg
    17341 attggggaga cagaccgcct gcctaagcaa acctttgaag ctttaaccaa ggctgaggaa
    17401 ttgactaaga acaacacagg attgattctt aattttgctc ttaactatgg tggacgtgct
    17461 gagattacac aggcgcttaa gttgatttcc caggatgttt tagatgccaa aatcaaccca
    17521 ggtgacatca cagaggaatt gattggtaac tatctcttta ctcagcattt gcctaaggac
    17581 ttacgagacc cagacttgat tatccgtact agtggagaat tacgtttgag caattttctt
    17641 ccatggcagg gagcctatag tgagctttat tttacggaca ccttatggcc tgattttgac
    17701 gaagcggcct tgcaggaagc tattcttgcc tataatcgtc gtcatcgccg atttggagga
    17761 gtttaggagg aaatatgacc caggatttac agaaaagaac cttgtttgca gggattgccc
    17821 tggctatttt cctaccaatt ttaatgattg ggggcctctt gcttcagata gcaatcggaa
    17881 tcatagccat gctagccatg catgaacttt tgaagatgag aggtctagag accatgacga
    17941 tggagggcct cttgaccctc tttgcaacct ttgcattgac cattcccttg gagaattacc
    18001 tgactttttt gccagttgat gggaatgtgg ttgcctatag tgttttgatt tcaatcatgt
    18061 taggaacgac cgtttttagc aagtcttata cgattgagga tgcggttttc cctcttgcta
    18121 tgagcttcta cgtgggcttt ggatttaatg ctttactaga tgctcgtgtt gcaggtttgg
    18181 acaaggctct cttagccttg tgtatcgtct gggcgacaga cagtggtgcc tatcttgttg
    18241 ggatgaacta tgggaaacga aagttagcac caagggtatc gcctaataaa acccttgagg
    18301 gtgccttggg tggtatttta ggagcaattt tagtaaccat tatctttatg atagttgaca
    18361 gtacagttgc tcttccatat ggaatttaca agatgtcagt ctttgctatt ttctttagca
    18421 ttgctggaca atttggtgat ttactagaaa gttcgatcaa acgtcatttt ggtgttaagg
    18481 attctgggaa atttatccct ggacatggtg gtgttttgga tcgtttcgat agtatgttgc
    18541 ttgtatttcc aatcatgcac ttatttggac tcttttaatc aaaagacgga ggaaacgcta
    18601 tgctcggaat tttaaccttt attctggttt tcgggattat tgtagtggtg cacgagttcg
    18661 ggcacttcta ctttgccaag aaatcaggga ttttagtacg tgaatttgcc atcggtatgg
    18721 gacctaaaat ttttgctcac attggcaagg atggaacggc ctataccatt cgaatcttgc
    18781 ctctgggtgg ctatgtccgc atggccggtt ggggtgatga tacaactgaa atcaagacag
    18841 gaacgcctgt tagtttgaca cttgctgatg atggtaaggt taaacgcatc aatctctcag
    18901 gtaaaaaatt ggatcaaaca gccctcccta tgcaggtgac ccagtttgat tttgaagaca
    18961 agctctttat caaaggattg gttctggaag aagaaaaaac atttgcagtg gatcacgatg
    19021 caacggttgt ggaagcagat ggtactgagg ttcggattgc acctttagat gttcaatatc
    19081 aaaatgcgac tatctggggc aaactgatta ccaattttgc aggtcctatg aacaatttta
    19141 tcttaggtgt cgttgttttt tgggttttaa tctttatgca gggtggtgtc agagatgttg
    19201 ataccaatca gttccatatc atgccccaag gtgccttggc caaggtagga gtaccagaaa
    19261 cggcacaaat taccaagatt ggctcacatg aggttagcaa ctgggaaagc ttgatccaag
    19321 ctgtggaaac agaaaccaaa gataagacgg caccgacttt ggatgtgact atttctgaaa
    19381 aggggagtga caaacaagtc actgttacac ccgaagatag tcaaggtcgt taccttctag
    19441 gtgttcaacc gggggttaag tcagattttc tatccatgtt tgtaggtggt tttacaactg
    19501 ctgctgactc agctctccga attctctcag ctctgaaaaa tctgattttc caaccggatt
    19561 tgaacaagtt gggtggacct gttgctatct ttaaggcaag tagtgatgct gctaaaaatg
    19621 gaattgaaaa tatcttgtac ttcttggcaa tgatttccat caatattggg atttttaatc
    19681 ttattccgat tccagccttg gatggtggta agattgtgct caatatccta gaagccatcc
    19741 gccgcaaacc attgaaacaa gaaattgaaa cctatgtcac cttggccgga gtggtcatca
    19801 tggttgtctt gatgattgct gtgacttgga atgacattat gcgactcttt tttagataat
    19861 cgaggaatat tatgaaacaa agtaaaatgc ctatcccaac gcttcgcgaa atgccaagcg
    19921 atgctcaagt tatcagccat gctcttatgt tgcgtgctgg ttatgttcgc caagtttcag
    19981 caggtgttta ttcttatcta ccacttgcca atcgtgtgat tgaaaaagct aaaaacatca
    20041 tgcgccaaga attcgaaaag attggtgctg ttgagatgtt ggctccagcc cttcttagtg
    20101 cagaattgtg gcgtgaatca ggtcgttacg aaacctatgg tgaagacctt tacaaactaa
    20161 aaaaccgtga aaaatcagac tttatcttag gtccaactca cgaagaaacc tttacagcta
    20221 ttgtccgtga ttctgttaaa tcttacaagc aattgccact caacctttat caaattcagc
    20281 ccaagtatcg tgatgaaaaa cgcccacgta atggacttct tcgtacacgt gagtttatca
    20341 tgaaggatgc ttatagtttc cacgctaact atgatagttt ggatagtgtt tatgatgagt
    20401 acaaagcagc ctatgagcgt attttcactc gtagtggttt agacttcaag gctattattg
    20461 gtgacggtgg agccatgggt ggtaaggata gccaagaatt tatggccatt acatctgctc
    20521 gtacagacct tgaccgctgg gttgtcttgg acaagtcagt tgcctcattt gacgaaattc
    20581 ctgcagaagt gcaagaagaa atcaaggcag aattgctcaa atggatagtc tctggtgaag
    20641 ataccattgc ttactcaagt gagtctagct atgcagctaa cttagaaatg gcaacaaacg
    20701 agtacaaacc aagcaaccgt gttgtcgctg aagaagaagt tactcgtgtt gcaacgccag
    20761 atgttaaatc aattgatgaa gttgcagctt tcctcaatgt tccagaagaa caaacgatta
    20821 aaaccctctt ctacattgca gatggtgagc ttgttgcagc ccttctagtt ggaaatgacc
    20881 aactcaacga agtcaagttg aaaaaccact taggagcaga tttctttgac gttgctagcg
    20941 aagaagaagt ggcgaatgtt gttcaagcag gatttggttc acttggacca gttggtttgc
    21001 cagagaatat taaaattatt gcagatcgta aggtgcaaga tgttcgcaat gcagttgtcg
    21061 gtgctaacga agatggctac cacttgactg gtgtgaaccc aggccgtgat tttactgcag
    21121 aatatgtgga tatccgtgaa gttcgtgagg gtgaaatttc cccagatgga caaggtgtcc
    21181 ttaactttgc gcgtggtatt gagatcggtc atattttcaa actcggaact cgctactcag
    21241 caagcatggg agcagatgtc ttggatgaaa atggtcgtgc tgtgccaatc atcatgggat
    21301 gttacggtat cggtgtcagc cgtcttcttt cagcagtgat ggagcaacac gctcgcctct
    21361 ttgttaacaa aacgccaaaa ggtgaatacc gttacgcttg gggaatcaat ttccctaaag
    21421 aattggcacc atttgatgtg catttgatta ctgtcaatgt caaggatgaa gaagcgcaag
    21481 ccttgacaga aaaacttgaa gcaagcttga tgggagctgg ttatgaagtc ttgacagatg
    21541 accgtaacga acgtgtcggt gttaaattta gcgatagtga cttgattggt cttccaatcc
    21601 gtatcactgt tggtaaaaaa gcggccgatg gcattgtaga agttaagatc aaggcaactg
    21661 gtgacaccat tgaggttcat gcagataacg tgcttgaaac gcttgaaatc ctaagcaaga
    21721 aataaaaact ataatcagaa gaaaaacaag gaaaaaatgt aactagtttt taccttgttt
    21781 tttctgtata atgggagaaa tgagtagata aagaggtaaa tgttatgcta agatttccaa
    21841 aggattttgt ctggggatcc tctacttctg gaccgcagac agaaggacgt gtagctggtg
    21901 acggtaaggg agacaatctc tgggattact ggttccaagt ggagccaaat cgttactata
    21961 atgggattgg ttcagataag acatcgactt tttatgaaaa ttgggagcgg gatattgagc
    22021 ttttgttaga gactggtcac acagtctttc ggacttctat tcagtggtca cggatttttc
    22081 cacaaggctg tggaaaagtc aaccctcaag gtgtggattt ttatcgtaag gtctttgagg
    22141 ctattaaggc taaaggaatt cgtctgttag tcaatctcta tcattttgat ttaccttttg
    22201 cccttcaaga ggatggtgat ggttgggaaa ataaggcgac agtctcagcc tatgaagact
    22261 atgctcgttt ttgttttgag acttatggag atttagtgga tcaatggatt acctttaacg
    22321 agctcatcgt tcctgtagaa tttggttatt tttatgatgc ccattatcca cataaggtgg
    22381 atgcagaggc agctgttaag gtagcctatc atacacaatt ggccagcagc cgggctgtta
    22441 aggcttgcca tgaacttttg cctgattcca agattgggat tgtcctcaac ttgacaccgg
    22501 cttatccacg tagccagcat cctgctgatg tcaaggcagc tcgtattgcg gccctttttc
    22561 aggcccaatc tttcttagat ccatctgtct tggggactta tccacaggag ttggtagaaa
    22621 tcttgcatga acacggtctt ttacctgatg ctacagagga agagttggaa ctcattcatg
    22681 ataatacggt ggacttcctt ggtgtgaact actatcaacc tttgcgtgtt atggctcctc
    22741 gatttgctaa gcatccagag agtccactct taccagaaca tttttacgag ccttatgtga
    22801 tgcctggacg taaaatcaat tctcaccgtg gttgggagat ttatgagcaa gggatttatg
    22861 acatcgccca aaatatcaag gaaaattatg gcaatattga atggatgttg actgagaatg
    22921 gtatgggtgt tgaaggggaa gaaaaattcc gtcaagatgg aatgattcaa gatgattacc
    22981 gtattgactt tgtaaaaggt catcttcgtg aacttcaccg tgccattgaa gatggtgcca
    23041 actgtaaggg ctacttgatt tggaccttta ttgactgctg gtcatggctc aacagctata
    23101 aaaatcgcta tggtttggtc gaattagact tggaaacgca agaacgtcgt ctgaagaaat
    23161 caggccactg gttcaaaaaa ttaagcgata ataatggatt ttaaaaagga ctctgactga
    23221 ttatcccaat cggtcagagt tttttgctta caggagctta atttgaacta taccaatttt
    23281 tactcttgac aagtgaaaga aacaagtata tactgttttt gctgattcta taaaagatga
    23341 attagactat accaatttta aggagaaagc acagcttgcc tgtgtcgtat atactatgtg
    23401 tggaattgtt ggtgttgttg gaaacacaaa tgcaactgat attttgattc aagggcttga
    23461 aaagcttgaa taccgtggct atgattctgc gggaattttt gtcctagatg gtgctgataa
    23521 ccatttggtg aaggctgttg gtcgtatcgc agaattgtct gccaagacag ctggtgttga
    23581 gggaacaact ggtatcggac atactcgttg ggcaactcat gggaaaccaa cggaagacaa
    23641 tgctcaccca caccgctctg agacagaacg ttttgtcttg gttcacaatg gggtgattga
    23701 aaactacctt gaaattaaag aagaatacct tgctgggcac cacttcaaag ggcaaacaga
    23761 tacggaaatc gccgtacatt tgattggaaa atttgcggaa gaagacggtc tctcagttct
    23821 tgaagccttt aaaaaagctc ttcatattat ccgtggttca tatgcctttg ccttgattga
    23881 ctctgaaaat ccagatgtca tctatgtagc gaaaaacaaa tctccacttt tgattggtct
    23941 tggggaaggc tacaatatgg tctgctcaga tgctatggct atgattcgtg aaaccaacca
    24001 atacatggaa attcatgacc aagagttggt aatcgtcaag gctgatagcg tggaagttca
    24061 agactatgat ggaaatcgtc gtgagcgtgc tagctacact gctgaacttg acttgtcaga
    24121 tatcggtaag ggaacttacc cttactacat gctcaaggaa attgacgagc aaccaactgt
    24181 tatgcggaaa ctcatccaag cctacacaga tgaggctggt caagttgtcg tagacccaga
    24241 tatcattaag gctgttcaag acgcagaccg catctacatc cttgcagctg gaacatctta
    24301 ccatgcagga tttgcttcta agaagatgtt ggaagaattg acagatacac cagttgaact
    24361 tggaatctca tctgagtggg gctacggtat gccacttctc agcaagaaac cactcttcat
    24421 ctttatcagc caatctggtg aaacagcgga tagtcgtcaa gttttggtca aggctaatga
    24481 aatgggaatt ccaagcttaa cagtgacaaa tgttccaggt tcaaccctct cacgtgaagc
    24541 caactatacc atgctccttc acgcaggtcc tgaaattgcc gtggcatcaa ctaaagccta
    24601 tacagcgcaa atcgcagccc ttgccttcct tgcaaaagca gtcggagaag caaatggtaa
    24661 tgctaaagcg caagcctttg acctggttca tgaattgtca atcgtagctc agtctattga
    24721 atcaactctt tcagagaaag aaaccattga agccaaggtt cgtgaacttc ttgaaacaac
    24781 tcgtaacgcc ttttacatcg gacgtggtca agattattac gtagccatgg aagcaagtct
    24841 caaactcaaa gagatttctt atatccagtg tgaaggtttt gcggcaggag aactcaagca
    24901 cggaaccatt gccttgattg aagaaggaac gcctgttttg gctctcttgt cagatccagt
    24961 tcttgccaac catactcgtg gaaatatcca agaggtcgca gcccgtggtg ccaaagtcct
    25021 cactatcgca gaagagaatg tagccaaaga taccgacgat atcgtcctta cgaccgtaca
    25081 tccatacctc tcaccaattt caatggtcgt accaacgcaa ttagtcgctt actttgcaac
    25141 cctccaccgt ggcctcgatg tggacaaacc acgtaacctt gccaagtcag taacggtaga
    25201 ataagctaaa aaagtctagt tatctaggct ttttcttgtg agcaaattgg ttgcttgtac
    25261 tcaagattcg tgttatactc ttagaaaatc tcttcaaacc acgtcaccgt cgccttgccg
    25321 taggtatggt tactga
//
LOCUS       DAVBCA010000028        24327 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.028, whole genome shotgun sequence.
ACCESSION   DAVBCA010000028 DAVBCA010000000
VERSION     DAVBCA010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24327)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24327)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24327
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.028"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..618)
                     /locus_tag="VQU19_001096"
     CDS             complement(<1..618)
                     /locus_tag="VQU19_001096"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HET2480352.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGIINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEK"
     gene            complement(769..2079)
                     /gene="secY"
                     /locus_tag="VQU19_001097"
     CDS             complement(769..2079)
                     /gene="secY"
                     /locus_tag="VQU19_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HET2480353.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            complement(2092..2532)
                     /gene="rplO"
                     /locus_tag="VQU19_001098"
     CDS             complement(2092..2532)
                     /gene="rplO"
                     /locus_tag="VQU19_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HET2480354.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            complement(2677..2901)
                     /gene="rpmD"
                     /locus_tag="VQU19_001099"
     CDS             complement(2677..2901)
                     /gene="rpmD"
                     /locus_tag="VQU19_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HET2480355.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            complement(2873..3367)
                     /gene="rpsE"
                     /locus_tag="VQU19_001100"
     CDS             complement(2873..3367)
                     /gene="rpsE"
                     /locus_tag="VQU19_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HET2480356.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            complement(3385..3741)
                     /gene="rplR"
                     /locus_tag="VQU19_001101"
     CDS             complement(3385..3741)
                     /gene="rplR"
                     /locus_tag="VQU19_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HET2480357.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            complement(3825..4361)
                     /gene="rplF"
                     /locus_tag="VQU19_001102"
     CDS             complement(3825..4361)
                     /gene="rplF"
                     /locus_tag="VQU19_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HET2480358.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEITLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            complement(4553..4951)
                     /gene="rpsH"
                     /locus_tag="VQU19_001103"
     CDS             complement(4553..4951)
                     /gene="rpsH"
                     /locus_tag="VQU19_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HET2480359.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            complement(5236..5505)
                     /gene="rpsN"
                     /locus_tag="VQU19_001104"
     CDS             complement(5236..5505)
                     /gene="rpsN"
                     /locus_tag="VQU19_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HET2480360.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            complement(5523..6065)
                     /gene="rplE"
                     /locus_tag="VQU19_001105"
     CDS             complement(5523..6065)
                     /gene="rplE"
                     /locus_tag="VQU19_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HET2480361.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            complement(6089..6394)
                     /gene="rplX"
                     /locus_tag="VQU19_001106"
     CDS             complement(6089..6394)
                     /gene="rplX"
                     /locus_tag="VQU19_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HET2480362.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            complement(6472..6840)
                     /gene="rplN"
                     /locus_tag="VQU19_001107"
     CDS             complement(6472..6840)
                     /gene="rplN"
                     /locus_tag="VQU19_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HET2480363.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            complement(6866..7126)
                     /gene="rpsQ"
                     /locus_tag="VQU19_001108"
     CDS             complement(6866..7126)
                     /gene="rpsQ"
                     /locus_tag="VQU19_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HET2480364.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            complement(7151..7357)
                     /locus_tag="VQU19_001109"
     CDS             complement(7151..7357)
                     /locus_tag="VQU19_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HET2480365.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            complement(7367..7780)
                     /gene="rplP"
                     /locus_tag="VQU19_001110"
     CDS             complement(7367..7780)
                     /gene="rplP"
                     /locus_tag="VQU19_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HET2480366.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            complement(7784..8437)
                     /gene="rpsC"
                     /locus_tag="VQU19_001111"
     CDS             complement(7784..8437)
                     /gene="rpsC"
                     /locus_tag="VQU19_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HET2480367.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            complement(8450..8794)
                     /gene="rplV"
                     /locus_tag="VQU19_001112"
     CDS             complement(8450..8794)
                     /gene="rplV"
                     /locus_tag="VQU19_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HET2480368.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            complement(8806..9087)
                     /gene="rpsS"
                     /locus_tag="VQU19_001113"
     CDS             complement(8806..9087)
                     /gene="rpsS"
                     /locus_tag="VQU19_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HET2480369.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            complement(9191..10024)
                     /gene="rplB"
                     /locus_tag="VQU19_001114"
     CDS             complement(9191..10024)
                     /gene="rplB"
                     /locus_tag="VQU19_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HET2480370.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            complement(10042..10338)
                     /locus_tag="VQU19_001115"
     CDS             complement(10042..10338)
                     /locus_tag="VQU19_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HET2480371.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            complement(10338..10961)
                     /gene="rplD"
                     /locus_tag="VQU19_001116"
     CDS             complement(10338..10961)
                     /gene="rplD"
                     /locus_tag="VQU19_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HET2480372.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            complement(10986..11612)
                     /gene="rplC"
                     /locus_tag="VQU19_001117"
     CDS             complement(10986..11612)
                     /gene="rplC"
                     /locus_tag="VQU19_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HET2480373.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            complement(11828..12136)
                     /gene="rpsJ"
                     /locus_tag="VQU19_001118"
     CDS             complement(11828..12136)
                     /gene="rpsJ"
                     /locus_tag="VQU19_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HET2480374.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            complement(12402..13019)
                     /locus_tag="VQU19_001119"
     CDS             complement(12402..13019)
                     /locus_tag="VQU19_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HET2480375.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNLLETDPYITSGRYLVVPKDAPNQKVTASLPVAHELESLQRDILALQAGMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            complement(13016..13606)
                     /gene="nrdG"
                     /locus_tag="VQU19_001120"
     CDS             complement(13016..13606)
                     /gene="nrdG"
                     /locus_tag="VQU19_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HET2480376.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVAGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLELLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKEIYEQVKRE"
     gene            complement(13599..14105)
                     /locus_tag="VQU19_001121"
     CDS             complement(13599..14105)
                     /locus_tag="VQU19_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2480377.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKSQSAHDGGFWDVEDFSYEEWL
                     EGNRNKEMGIWLPENRVPSIQFVLFGESGCALGFLNLRLRLNEGLLNYAGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDARNGVER
                     YWIEVANE"
     gene            complement(14149..14289)
                     /locus_tag="VQU19_001122"
     CDS             complement(14149..14289)
                     /locus_tag="VQU19_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480378.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            complement(14301..16508)
                     /gene="nrdD"
                     /locus_tag="VQU19_001123"
     CDS             complement(14301..16508)
                     /gene="nrdD"
                     /locus_tag="VQU19_001123"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HET2480379.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNCRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            complement(16628..18166)
                     /locus_tag="VQU19_001124"
     CDS             complement(16628..18166)
                     /locus_tag="VQU19_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HET2480380.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            complement(18203..18346)
                     /locus_tag="VQU19_001125"
     CDS             complement(18203..18346)
                     /locus_tag="VQU19_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480381.1"
                     /translation="MLTKEEVNDMIEFKQTHLHRFREIETFVKLCKKSLKQPSQADNP
                     RTF"
     gene            complement(18424..19956)
                     /gene="cls"
                     /locus_tag="VQU19_001126"
     CDS             complement(18424..19956)
                     /gene="cls"
                     /locus_tag="VQU19_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HET2480382.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            complement(20102..20659)
                     /locus_tag="VQU19_001127"
     CDS             complement(20102..20659)
                     /locus_tag="VQU19_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HET2480383.1"
                     /translation="MTPLFELVILGELLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPVAQQQVQQPAQQPAQQNTNTANAGGNQNQAAPVQNQPVAQP
                     TDIDGTYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKI
                     YTVNGNQIVVDDMDRDPSDQIVLTK"
     gene            complement(20656..21906)
                     /locus_tag="VQU19_001128"
     CDS             complement(20656..21906)
                     /locus_tag="VQU19_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HET2480384.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRIQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLADQVKE
                     MEKTLLQTPDQLSFFEMLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVNLYQA
                     GQDFLMLNGDFSSSLLNFSQLNIGLEGVYQQENAALALQTFLLFMGEGKEAVDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGALKRKD
                     YQGMLGYLTEKLPQVELKVTGFDYQGALDERDVTGYDIVSSCREFISSFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            complement(22114..22419)
                     /locus_tag="VQU19_001129"
     CDS             complement(22114..22419)
                     /locus_tag="VQU19_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HET2480385.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            complement(22435..22854)
                     /gene="ruvX"
                     /locus_tag="VQU19_001130"
     CDS             complement(22435..22854)
                     /gene="ruvX"
                     /locus_tag="VQU19_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HET2480386.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPLDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            complement(22858..23124)
                     /locus_tag="VQU19_001131"
     CDS             complement(22858..23124)
                     /locus_tag="VQU19_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HET2480387.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            complement(23211..23780)
                     /locus_tag="VQU19_001132"
     CDS             complement(23211..23780)
                     /locus_tag="VQU19_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET2480388.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLTIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            complement(23846..24244)
                     /gene="spx"
                     /locus_tag="VQU19_001133"
     CDS             complement(23846..24244)
                     /gene="spx"
                     /locus_tag="VQU19_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HET2480389.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
BASE COUNT         6740 a         5398 c         4560 g         7629 t
ORIGIN      
        1 tttttcaata tctgagaaga catcattgat atcttgatta ccttcgatgt catgaaccaa
       61 acctttggca cggtagtgag caatgattgg ttctccttga gcaatattaa catccaaacg
      121 acgttttact gtctcaggct tatcatcttc acgttggtag taatcttctt ctttatagtc
      181 aactggtggg ttaaagacct tgtggaaagt ttctccagtt acgcggtgga tgatacggcc
      241 actcaaacgt tccaagaggc tgtcagggtt cacttcaata ttgataatac cttctagttc
      301 aatgccaagt tcagccaatg ttttgtccaa ggcatgagct tgttcaattg tacgtgggta
      361 accatccaat aagaatcctg tttctttaat atcatcttgt gaaaggcgtt cttttacgat
      421 tccatttgta acttcgtcag gaaccaattc acccttgtca atatatgact tagcaagaac
      481 acccatttca gtttgatttg ccattgcagc gcggaacata tcacctgttg agatatgtgc
      541 aacatggaat tgttctacga tttttgctgc ttgagttccc ttacctgcac caggtaagcc
      601 cataatcaaa agattcatga tttgatctcc ttattttatt tttaaataga agcaaaaagt
      661 cttttcaccc ctatttaaaa acaaaataga agaggggaga tccaactctt acaaatgtca
      721 gagtttaaac ctccactccc tcagtattta ctgattcagt aaatactttt attctgttct
      781 gtccatgaaa ccaacatact tacgtttcaa taggtaacct tccaattgct tgattccttc
      841 gatacctgta gagataatga tcaagagact tgttccacca aaggcaacaa catcagaaag
      901 accaaataca tctttagctg caatcggtaa aatggaaatc acaccaagga agagggaacc
      961 aacagttgca agacgacgaa gaagtttaga catatattct tctgtacctt taccaggacg
     1021 aactccatgg atataggcac cactcttttg taggctctct gctgcttttt caggattaat
     1081 ctgtacaaac gtatagaaga atgtaaagag aataatcaac aaagcataca tggcaatacc
     1141 agttggagaa gtagttgcca acatctcttg tgctaccctt acccaagccc aatcatgacc
     1201 tgtggcactc aaaaactgaa gaatagccgc aggcgctgca gtaatcgaac tggcaaagat
     1261 aacagggata actccagcag ggtttacctt taacggaagg taagagctag atggagcacc
     1321 ttgtgcaacc ttagtatatt ggattggaat tttgtattct gcttgttgaa cataagttgt
     1381 aaagtaaata atcaacaata cagtaataat caaaatgatt acgaaaatga tagatgaagt
     1441 gatacggcta cttgggacgt tcacaaagta gtccacatag atgccctgaa tcatctctgg
     1501 aattgaggaa acaatcccgg caaagataat catggaaaca ccgtttccgt atcccttatc
     1561 tgtaatttgc tcacccaacc aagtgacaat catactacca gctgttaaga tgataccaat
     1621 cgtcagaaaa acttgtggag ttaaagcagt tttaatcaat tgagctccag ccaaggtatt
     1681 aaaaccagct gtaatcccga tagattgcac aaaagcgaga actagagcaa tataacgagt
     1741 agcttgattc aattttcttc gacctacttc cccttgttta ccccactcta caaacttggg
     1801 taaaatatcc atttgcaaga gttggacaac aatagaagcg gtgatatagg gactaactcc
     1861 tagggcaaaa atcgaaaagt tttttagggc attccccgac accaagctca acatgtttaa
     1921 gaaggataat ccacttaaag cattcaagct attggcattc acaccaggaa ctgtaatgct
     1981 agttccgata cgaaagacca aaacgataaa aattgtaaat aaaatttttg atcgaacctg
     2041 cttgacttta agagcttctc ttaataattt aaaaaacata ggtcacctct cttagatgac
     2101 ttctactgaa ccacctttag cagtgatagc ttcttcagct gatttagaga atttagctgc
     2161 tttcacagtc aatttcttag tcaactcacc gttaccaaga attttaatac ctgacttttc
     2221 agctttaaca attcctgctt cgataagaac aactggagtt acttcagcac catcttcaaa
     2281 gacgttcaat tggtcaaggt tcacaattgc gtattcttta gcgttgatgt tagtgaatcc
     2341 acgttttgga agacgacgga acaatggagt ttgtccacct tcaaaaccaa ggcgaactcc
     2401 gccaccgcta cgagcttttt gacctttttg accacgacca gatgttttac cgttacctga
     2461 tgaagtacca cgaccaacgc ggttacgtac tttacgagaa ccttctgcag gtttcaattc
     2521 atgaagtttc atttttattt tctcctcttt tgtaaaatgc tagcgccgat aagggagaaa
     2581 aggttgtctc ccccatcaac tcgcctatac gatgtcatca tagatgacta tatctagttt
     2641 taggggatgg tacagtgcac atcccctaaa acttcattag tttacttctt caactgttac
     2701 taagtgagat actgctgtaa tcataccacg gatagcagcg ttatcttctt taataacaga
     2761 gctgttcaat ttgccaagtc caagtgctac aacagtttta cgttgtgatg gaatgcgtcc
     2821 gattggagac ttagtcaaag taattttaat ttgagccatt ttatcccctt tcttatgcca
     2881 aatcagaaac tgaaatacca cgaagggcag caatttcttc agcgcgtttc aattgtttca
     2941 aaccttcaac agttgcacga acaatgttga ttggagtgtt agaaccaagt gatttagatg
     3001 taatatctgc cacacctgcc aattccacaa cggcacgaac tgcaccacca gcggcaactc
     3061 cagaaccttc tacagcaggt ttcaacaata ctttagctcc accgaattct gaaagaactt
     3121 cgtgtgggat tgttgttcca accataggaa cttcgatcaa gtttttctta gcatcatcta
     3181 ctgctttacg gattgcttct ggaacttctt gagctttacc agtaccaaat cctacgcgac
     3241 cattgtggtc accaacaaca acaagagctg cgaaacgaag acgacgtcca cctttaacaa
     3301 cttttgtaac acggttgaca gcaactacgc gttcttctaa ttcaactgca ttgtctttaa
     3361 atgccatttt ctagtgtcct cctattagaa tttcaatccg ttttcacgag ctgcatcagc
     3421 caaagctttc acacgtccgt gatatagata tccaccgcgg tcgaacacca cttctgaaat
     3481 acctttagcg tttgcacgtt ctgcaacgag tttaccgaca gcaacggctt gttcagtttt
     3541 agttcctttt gaaacttctt tatcaagagt tgaagcactt gcgagcgtta cacccgctac
     3601 gtcatcaatc acttgagcgt agatgcctgt attagaacgg aatacgttca aacgtgggcg
     3661 atcagcagtt ccagagagtt ttccgcgaac gcgacggtgg cgtttttggc ggagtttgtt
     3721 tttatctggt tttgaaatca cagttttcac ctctttagtt ttaaatcgtg tgctatgcac
     3781 aaagttggaa aataggttgg tggttgatga tcaaccactc aacattattt acctgtttta
     3841 ccttctttac ggcgaacgaa ttcaccaacg taacggatac ctttaccttt atatggttct
     3901 ggtgaacgaa ggctacgtac gtaagcagct gtttgaccaa ctacttcttt tgaaattccg
     3961 ctaacaacga ttgttgttgg gtttggaagt tcaaaagtaa ttccttctgg agcttcaact
     4021 tcgtctggat gagatttacc aacagccaaa acaagtttag atccttgaag ctgtgcacgg
     4081 taaccaaccc cacgcatttc aagttctttc ttgaatcctt ctgatacacc aacaaccatg
     4141 ttgttcaaaa gggcacgagt agttccgtgg atagttttca tttcttttga atcgtttgga
     4201 cggtgaagag ttatttcagt accttccaca cggatttcaa tatcttttga gaactcacga
     4261 gtaagttctc ctttaggtcc ttttacagtt acaacgttgt cattgttagc gagttcaaca
     4321 ccagcaggca acacgataac tttattacca atacgtgaca tgtttatttt ctcctgttaa
     4381 attgtcaggc cagaacggcc agttttcacg gggttcagat acttatttag ttcaagagct
     4441 gaactgaaca cgctctaaga actgtgcaaa atagataagt tggcttgttt gtaaacaaac
     4501 ttctccaact tcctaatttt gctttgttct ttacgagctt tgtatcttga ttttaccaaa
     4561 cgtaagcgat aacctcacca ccaacattct tttggcgtgc ttctttatca gtaagcaaac
     4621 cttcagaagt tgaaaggatg gcaattccaa gtccgttaag aacttttgga aggtcttcac
     4681 gttttttgta gacacgaagt cctggtttag aaacacgttt caagttagtg ataactttct
     4741 caccatttgg tccgtattta agaaatacac ggatgacgcc ttgtttgtca tcttcaatga
     4801 tttcaacgtt ttttacaaaa ccttcgcgtt taaggatttc agcaatccct tttttgatgt
     4861 ttgatgcagg tacttcaagt acttcgtgtt tagcttggtt agcattacga atacgagtta
     4921 ggaagtctgc gattgggtca gtcataacca ttttgttttt ctcctcttac tagtagtttg
     4981 caagttgcac ttgctagtta atacatgata caaagagcgt aacagcacga gcaaaaatag
     5041 acaatttaat gcagaagcaa tgctccaaag caaattggtc ttttttgcca aagctgtagc
     5101 tcgtgttcaa attggcaagc ccaattgaac ccgggctaaa ctctgtgtga aaaagataaa
     5161 ctttcctaga aactttagtt tcttcgtcaa gtttcctatt tttacttgga gttttgacgc
     5221 tcttgatatc ttaaattacc aagatgcttt tgttacacca ggaatttgac ctttatgcgc
     5281 aagttcgcga aaagcgatac gactcagacc aaatttgcgg taaactgaat gtgggcgccc
     5341 cgtaactcta caacgattat gtaaacgagt cggtgaggcg ttgcgaggta atttagataa
     5401 accttcgtag tcccctgccg cctttaatgc agcacgtttt tcagcataac ggtcaacaat
     5461 tttttggcgt ttagcctctc tagctaccat tgatttttta gccattagat ttacctccta
     5521 tattattttg caaaaggcat tccaaggcct gtaagcaatg cacgtgactc ttcgtcagtg
     5581 ttagcagttg ttacgataac gatgtcaaga ccacgagttt tgtcaacgtc atcgaagttg
     5641 atttctggga agattaattg ttctttcaca ccaagtgtgt agttcccgcg tccatcaaat
     5701 gattttgttg gaacaccgtg gaagtcacgt acacgtggaa gtgaaactga taccaattta
     5761 tccaagaatt cgtacatacg ttcaccacga agggtaactt ttgcaccgat cgcaacacct
     5821 tcacgaagac ggaagccggc gattgatttt ttagctttag tgataagtgg tttttgacct
     5881 gagataagtg ccaattcttc agcagctttt tcaaggcttt tagcgtttga tacagcttca
     5941 ccaacaccca tgttcaaaac aatcttatct actttaggca cagccatcac tgatgagtag
     6001 ttgaattgtt ctgtcaaagc aggaactact tcattaagat atttttcttt taaacgattt
     6061 gccattatac ttctcctttc cttcgtgatt aatcaagcac ttcgcctgat tttttgttgt
     6121 agcgaacttt tttaccgtct acaaatttgt aaccaacacg accagctaca ccatttttgt
     6181 ccaaaacttg aacgtttgat acgtggatag ctgcttcttt ctcgatgata ccaccttgag
     6241 gaagctcgtt agttggacgt tggtgtttct taacaatgtt aacaccttca acgataactt
     6301 tgtttacttt tggaagggca gtaaggacaa cagcttctgt tcccttatct ttaccagcga
     6361 ttacgcgaac tttgtcgcct ttttttacaa acattaggtt tctccttgat ttttcttacg
     6421 cccataaggg caccctagct tgaagctagg ggactagttt gttcctaaaa attaaagtac
     6481 ttctggagca agtgacacga tcttcatgaa gccaccttca cgcaattcac gtgcaactgg
     6541 gccaaagata cgtgttccgc gaggagtttt gtcttcacgg atgataactg ctgcgttttc
     6601 gtcaaatttg atgtatgaac catcagcacg acgagcacct gatttagtac gaacgataac
     6661 tgctttaaca acgtcacctt ttttaaccgc accaccagga gtagcttgtt ttacagatgc
     6721 cacgataaca tcaccgatgt ttgcaaattt acgtcctgaa ccaccaagaa ctttgatagt
     6781 caagatttcg cgagcaccgc tgttgtctgc gactttcaaa cgagtttctg tttgaatcat
     6841 ttcagttttc tcctttcagg tttgattaga tgatgaccgc ttcttcaaca acttctacaa
     6901 gacggaaacg ttttgtagct gaaagcgggc gagtttccat gatacgtacg atatcgcctt
     6961 ctttggcaac attgttttca tcatgagctt tgtatttttt agagtagtta atacgtttac
     7021 catagactgg gtggttacgt tttgtttcaa ctacaactgt gattgtcttg tccattttgt
     7081 cagatacaac acgtccaaca agaactttac gattattgcg ttccattgaa atttctcctt
     7141 ccctagtcta ttatttcgct tcagattgaa ctgttttgat acgagcgatt tgttttttaa
     7201 cttctttcaa gcgagctgtt tgttccaatt gaccagtagc agcttggaaa cgaagttcaa
     7261 acaattcttt tttcaattcg ttttcgcgct tcgcgagttc ttcttgagaa agaccacgaa
     7321 gttctttaac aaattctttt acttcattaa gtttcatgcc ttctccttat tctgcttcac
     7381 gttttacgaa tttacattta actggcaatt tgtggctagc aagtcgaagc gcttcacgtg
     7441 caatctcttc agatacacca gcgatttcga acatcacttt accacgttta actggtgcta
     7501 cccaaccttc aggtgcccct ttaccagatc ccatacgcac accgatagct ttagcagtgt
     7561 atgatttgtg tgggaagatt ttaatccaaa ctttaccacc acgtttcatg taacgagtca
     7621 tggcgatacg agcagcttcg atttggcggt tagtgatcca gtggctagtt gtagcttgaa
     7681 gaccgtattc accgaatgct acttcttttc caccttttgc ttcaccgcgc atttttccac
     7741 ggaactcacg acggtgttta acacgtttag gtactaacat tggttattta cctcctttag
     7801 tgtttttacg agctggaaga acttcaccac ggtagatcca tactttaaca ccaagtttac
     7861 cgtatgtagt atctgcttct tcccaagcgt aatcgatatc tgcacgaagt gtgtgaagcg
     7921 gaacagttcc ttcagagtat ccttcagcac gggcgatatc tgcaccgttc aaacgacctg
     7981 atacttgagt tttgattcct ttagctccag cacgcattgc acgttggatt gcttgttttt
     8041 gtgcacgacg gaaagcaaca cgttgctcca attgacgagc aattccttca cctacaaggt
     8101 gagcatccaa atcaggttgt ttgatttcga tgatgttgat gtgtacttgt tttccagtca
     8161 atttgttaag ttttgcacgg agtgcatcaa cgttagcacc acctttaccg ataaccatac
     8221 ctggtttagc agtgtgaagt gaaacgttaa ctttgtttac tgcgcgttcg atttcaatag
     8281 ttgaaactgc tgcgtcagca agttcttttt gaacgaattt acggattgca agatcttcat
     8341 gaaggtaatc cgcgtattct ttttcagcat accatttggc atcccaatca cggatgatgc
     8401 cgacacgcat accaattgga tgtacttttt gacccacgat tttacctcct tatttttctg
     8461 caacagctac agtgatgtga gctgtacgtt tgttgattgg tgaagctgaa cctttcgcac
     8521 gtggacggaa acgtttcata gttggtcctt cgtttgcgaa tgcttcagat actaccaaat
     8581 tagctttatc caaaccaaag ttgttttcag cgttagctac agctgagttc aaaactttca
     8641 agatgatttc agcagctttg tttggagtga atgtcaagat tgcgattgca tcggctacgc
     8701 ttttaccacg gatgttatca agaacaagac gtgatttacg aggtgaaaca cgtactgtac
     8761 gagccattgc tttagctgaa gtaatttctg ccatttatgt tctccttatt ttctacgtgt
     8821 tttcttgtcg tctgcagcgt gacctttgta agtacgagtt ggtgcaaatt caccaagttt
     8881 gtggcctacc atgtcttctt ggatgtaaac aggtacgtgt ttacgtccgt cataaactgc
     8941 aatagtgtaa ccaatgaaac ttgggaagat cgttgaacga cgtgaccaag ttttaataac
     9001 ttttttcttt tcgtcgttag cttgagcttc aacttttttc atcaaatgct catcgacgaa
     9061 aggtcctttt ttaagactgc gtcccatttt tatattttct cctttaaatg ttgtaccaca
     9121 gcggcttgca ctcctatgga gcgctaccga gctggcggat ttactagttg cttaagcgac
     9181 tagtttaata ttatttctcg ttgcgacgac gaacgataag tttgtcagat ttcgctttct
     9241 tgttacgagt tttaagacca agagcaggtt tgccccatgg agtagatggt gctttacgac
     9301 caactggtgc tttaccttca ccaccaccgt gtgggtgatc gttagggttc attacagaac
     9361 cacgaactgt tgggcggata cctttccaac ggctacgtcc tgctttacca aggtttacaa
     9421 gtccatgttg ttcgtttccg acaacaccaa ctgtagcacg gcaagttcca agaatcatac
     9481 gaacttcacc tgattgaaga cgaacaagaa catatttacc ttcagaaccc aatacttgag
     9541 cagatgcacc agcagcacgt accaattcac caccacgacc tggtttcaac tcgatgttgt
     9601 gaatcaaagt accaactggg atgttagcaa gtggaagagc gtttccgact ttgatatctg
     9661 cttctggacc tgaaacgata cgttgaccta cttcaagacc ttttggagcg atgatgtatg
     9721 ctttcacacc gtcagtgtag tgtacaagag cgatgtttgc agaacggttt ggatcgtact
     9781 cgattgtttt aacaactgct tcaacgttgt ctttattacg tttgaagtca accaaacggt
     9841 aaaaacgttt gtgtccacca ccttggtgac gaactgtgat acgaccgttg ttgttacgac
     9901 cagccttgct cttcaatgca acaagcaatg atttttcagg agtgcttgtt gtgatttcag
     9961 cgaaatccaa agaagtcata ttacggcgac cgtttgttgt tggtttataa acacgaattc
    10021 ccacgatatt tcctccttag attattcagc ttcagcagca aacaactcga ttgctttaga
    10081 atcagctgta agtgtgatga tagctttttt agttttgtta gtaaaaccag tgtaacgtcc
    10141 aacacgttta gcttttggtt ttacgttgat tgtgttaaca ttggcaactt taacaccttc
    10201 gaaagcagct tcaacagctt gcttgatcaa aagtttgtgt gcacgagtgt caacttcaaa
    10261 tacatatttt cctgcttcaa gttgagccat tgagctttca gtgatgacag gttttttgat
    10321 aacatcatac aaattcatta tgcaagaacc tcctcgattt tagagatagc tgcttgtgtg
    10381 acaagaagtt tgtcgctatt tgcgatgtca agaacacttg cagttgtagc agttgcaact
    10441 ttcacgtttg gaaggttacg agctgaaaga gctgcgaatt catttccttc ttcaaggata
    10501 acaagaactt tagaatcgat gctcaatgct gcaagaactt ttgcaaattc agcagttttt
    10561 ggagctgtaa atgaaagagc gtctacagct acgaatttgt tttcagcaac tttttcagag
    10621 taaactgatt taagagctag gcgacgaact ttttgtggaa gtttgtagcc gtatgaacgt
    10681 ggagttggtc cgaagacaac accaccacca cgccattgtg gtgagcggat agaaccttga
    10741 cgagcacgtc cagttccttt ttgacgccat ggtttgcgtc caccacctga tactgcagag
    10801 cggtttttaa cagcgtgtgt tccttgacga aggcttgcgc gttggctgat gattacatca
    10861 aacacaactg attcatttgg ttcgatacca aatactgcat cgctaagaac aacttggcca
    10921 gcttctttac cagtttggtc aaataatgtt acgtttgcca ttgtgactga tttccccttt
    10981 ctttattatt taccagcttt aactgctgat ttgatagtga taagagattt cttagcacct
    11041 ggtacgttac ctttgataag gataacgttc ttttctggaa caacttgtac aacttcaagg
    11101 ttttgaattg ttacgcggtc gccacccata cgccctgcaa ggtttttacc tttgaatacg
    11161 cggttaggtg caacaggtcc catagaacct ggacgacggt ggtaacgaga accgtgagcc
    11221 attggtccac gtgattgtcc gtggcgtttg ataacacctt ggaaaccttt acctttagaa
    11281 gtaccagtta cgtcaacaac gtctccagct gcgaatgttt caactgtaat ttcagcacca
    11341 acttccaagc cttcaacgtt tttgaattca cgaatgaagc gcttaggagc cgtgttagct
    11401 ttcgctacat gtcctttagc aggtttgttg ctcaatactt cgcgtttgtc atcgaaacca
    11461 acttggatag cgttgtatcc gtctgtttca acagttttaa cttgaagaac aacgtttgga
    11521 gttgcttcaa taactgttac agggatcaat tcgccagctt cagtgaagat ttgagtcatt
    11581 cccacttttt tccctaagat tccttttgtc atgagaaaat agttcctttt ctatattttt
    11641 attcaaaaag tttttaacga gcgtttttta tgctcaagtc taagatacaa agggcgtcaa
    11701 actcaacgtg aaaataggaa actgacacag tgtctagcag acgcgaggaa gtttatcttt
    11761 ttcacaccga gtttagcccg tgttcaatta gattgaaaca ccagcctctg ctcttttata
    11821 ttttagatta aagtttgatt tctacgttta caccacttgg aagatccaat ttcatcaagg
    11881 catcaactgt tttttgagtt gggttaacga tatcgatcaa acgtttgtgt gtacgcattt
    11941 caaattgttc gcgagagtct ttgtatttgt gagtcgcacg aatgattgtg tagaggctac
    12001 gttcagttgg aagtgggatt ggacccgcaa cttgtgcacc tgtacgagta gctgattcta
    12061 cgatttttgc agccgctgtg tcaagcgtac ggtgttcgta agctttcaaa cggatacgga
    12121 tttttttgtt tgccatcttt ttctcctttt cgtctattta agataatagg ctagctccac
    12181 aagaaaaccg acgcggtgtt gcgtggcaat gcaaccgagc gtgtcgcaac ctcttgcatc
    12241 aaaactaagg ctgtaattta cagcaccata atagaataac acaaatcccc tgcgattgca
    12301 agggatttgt taggtttttt cgttttttgg ggatgaaact gttttcctac tttttctttc
    12361 taaaattagg gattttcttc tatatttctt ctatacataa gttaagtcct cttgacatca
    12421 aatttatctt ctgattggtc cactaagata tccgccttag actcagtttc tttatagtat
    12481 cgcagatact gctcccgtct catctgatgg ctagccaata taaaggatgc atcgcgattt
    12541 ctcacagtcg tatctctagc aaggcgtcgc tttaattcgg tctcctcatc cgtgtagaaa
    12601 cagatggttt tttcaaagag ttccttgggt agaaagccaa cagacatccc ttcgacaatc
    12661 aaaattggtt tggctccaga caagacctca ctagccttcc aaggttcttc aattgtcaag
    12721 acatccatac ccgcctgcaa ggcaaggata tctctctgca aactctccag ttcatgcgcc
    12781 actggcagac tggctgtcac cttttgattc ggcgcgtcct tgggtactac caaatagcgt
    12841 ccggaggtga tatagggatc tgtttctagc aaatttactg tagtagaatc taaagcttgg
    12901 tacaattcct gtgcaaaggt tgatttacct gaagctccat gaccgtatat tcccagtgtc
    12961 ctgactttcc ccgtctcgat ctctgagact agttggtcta ctaagtcttt tttcttcatt
    13021 ctctcttcac ctgttcatag atttcttttc cgtcattgag cttgtcccaa atcactactt
    13081 gcccactttt gagcgatttt tgcacatcga taattcgttg gttagacgaa cctcgaaact
    13141 ggagcataag atttctctta gttcgatcat atcttccatc gacaagaatg tcaatcagtg
    13201 acaagagttc cagtttatct ggagtttcca acatcatttc ttcccaagtg tagcccgtcc
    13261 aggaccagat gtccttgtct ggcaattcct tccgaatccg cttaacaagt ggcaagagaa
    13321 tcccagtatt aagaaaaggc tcccctccta gtaaggttaa cccctgaaca taaggctggg
    13381 caagatctgc cataatctgt tcttccaact cagctgtata gggaatgcct gcattgaagg
    13441 accaggtcgc tacattataa cacccctcgc agtgaaacat acagcctgct acatagagag
    13501 agttacgcac gccttcgcca tcaacaaagt taaaggcctt gtagtcaatg atacgacctt
    13561 gactaagttc ctcgcttttc cattcttgtg gttttggatt attcattcgc tacctctatc
    13621 caataacgct cgactccatt gcgagcatcc tcaaatattc caccatttgc tagaatgact
    13681 gctctgctag caggattatt cacgctacag gtcaccagag ctttcttgat gttcttttcc
    13741 ttagcaactt gcaagccctg acggagagtc tcttttgcat aacccttgcc tctttcagat
    13801 ggacggatgg agtagccaat gtggccagca taattcagta acccctcatt cagtctcaat
    13861 cgcagattca aaaatcctag agcacaacct gattcaccaa acaatacgaa ctgtatcgat
    13921 ggaacgcgat tttcaggtag ccatattccc atttctttat tacggttacc ttctagccac
    13981 tcctcgtaag aaaaatcctc aacatcccaa aatcctccat catgggctga ttggctcttt
    14041 tcaaactctg tcatcatatc taaaacagct ttcttatccg ctaatcttgg tctgcgtaat
    14101 tccatcctta cctcccacta tgagaaaagc gagagctggc tctcactttt attttttctt
    14161 gttcttgttt aaaaattgtt ctctgaagct aagcaagcgt tctttcttac cagctccacc
    14221 tttagagtgt ttctcgtgat aacgggtcac ttgtgcgcgc cccttatcgt ctagttgata
    14281 ttttcccatt tcatttcttt ctaatttgtt acttgatgcc cagctatttt aatcgttgaa
    14341 ccattcatat gtttgacacg cgcagcgatt tccttgtgac gcccgttgac catcggtctt
    14401 gcttgaggat tacctaggta gccacaagtt cgcttcacca catctactgt tttagggtcg
    14461 ctattgccac agtttggaca agcaaaccct ctctcagttg gttcaaaatc cccttcaaag
    14521 tcacacttgt agcaacggtc aatcggagta ttggtgccta gatagcctac acggtcataa
    14581 gcataatccc agacagcttc caaggccttt ggattttgct gaaggactgg atactcacaa
    14641 taatggatga aaccacctga cgcacctgct tctggataga ctttctcaaa gtccaatttt
    14701 tcaaacggtg ttggattttt acgaacatcg tagtggaaag agttggtgta gtattccttg
    14761 tctgtgatat caggaataga gccaaacttg tctatatcta gtcggcagaa acggtctgtc
    14821 agactttcgg atggtgttga gtagatagag aaatggtagc catattggtc tgaccactct
    14881 tctacacggc gtttcatatc gtgaatgatg tctagcgtga attccttagc atctggatta
    14941 ctttcccagc tgttaccaaa gaaaactgtc gctacttcat acaagccgat atagcccagc
    15001 gaaacggtcg cacgacaatt cttaaagagc tggtcaacac tttcttcttt acctagacga
    15061 tggccaaaag caccgtactg ataaaggata ggagcattcg ctggtgtcgc ctctttagtg
    15121 cgttcgacac ggtaaacaag agcatcttct gcgatattca ttcgctcgtt gaagatttcc
    15181 cagaacttat tcatatcacc ttcagactca agagcaatac gaggcagatt aaccgtcaca
    15241 acacccagat tcatgcgacc tgaattgact tctacaccat tttcatcctt ccatccttgg
    15301 aggaaagaac ggcaacccat aggcaccttg aaggatcctg tcaagtcaac aatcttatcg
    15361 taagataaaa catctggata catccgtttg gttgcacact caagagccaa ctgcttgatg
    15421 tcgtagttgg gagttccttc ctctaaatta aggcctcttt tcagagtgaa aataagttta
    15481 ggaaagatag ccgtacggtg ttctgaacca agacccttga tgcgaatgtt taaaatagct
    15541 ttttgaattt ctcgttcaaa acgactggtt cccagaccaa aacctagcga agtaaaaggt
    15601 gtttgtccat ttgaagtgaa gagagtattg atttcatact caagagattg catggcatcg
    15661 tagatgtcct tttgcgtttt cttccaagcg taatcttccc gtttttcagg caatacccac
    15721 tcttctgcat ctttgagatg tttttgatag ttcttctctg cataaggcgc caaaatttca
    15781 tcgatacggt cagctgaaca gccaccgtac tggctagaag caacgttggc aatgatttga
    15841 gaaatctgtg ctgtcgcagt ctggatagac ttgggactct ctacctctgc atttccaatc
    15901 ttaaaaccat tttccaacat acccttaaaa tcaatcaaac agcagttggt cataggggta
    15961 tagggactgt agtccaaatc gtgatagtgg atatccccct tttggtgggc attggctacg
    16021 tgcttaggaa gcatttgcag tccgattgat ttcccaacaa tccctgctgt caaatcacgc
    16081 tgagtgttaa agacatcact gtctttatta gcattttcat tgacaactgt ctggtctttg
    16141 ttgagaagtt tatgaatact aaagttgata tccgtcgctt ttgagcgctc aaaatccctc
    16201 tgtgtccgat aagtaatata ctcctcagcc agcgcatatt ctttggcttc aaggagttca
    16261 tgttctacga tattttgaat ttcgtaaatc ttaattccct gtggaaagcg actatgaatt
    16321 tctgtaataa ttctctcagt cagatcattg aggcgttttt caaccagggg tgtcacatcc
    16381 ataaccttgt cagctgcctt gtggagagcc ttgtcaatct tgtccacatc aaatacaaca
    16441 cgtctcccat ctcgtttctc gacgaagaga gttggcaaaa ttgtaatttt ttcttctagt
    16501 gcaatcatat gcatgctctt ttctaaaatg ttctttctaa aaagtattat accactctaa
    16561 aaagaaaaat caatatcttg tgttaaaaat cctaaaattt ttaaaaatac acaagatatt
    16621 gatttggtta tttaatttta tagactttaa actctgagta atcagtcttt acttgttggt
    16681 aattttcttt taaaagtgtt tccacttcag accagactac caccttgtca tttaccacaa
    16741 tcaccttagg ttgtttttct ttcaagtcat taagtaactt attacgattt tcctcagttg
    16801 ctgtatagtg caacggggac aaaatcgccg atggcgacaa gcgctcactc ttacgataaa
    16861 gagtcgcagt atcatcccat gcatagatag catcttccgt atttgtctcc tcttttacca
    16921 aatcagcaag acgattacgt tcttgataag gtactggata aaggacaaac ttcatcaaaa
    16981 aaggaacaga caaaagatag acaaacccaa aaactagcag atatagattt cctttgaaga
    17041 aacgactcca taggctaact ggcgtttctc ttcggcttct tctagcacta cgccccctct
    17101 gttgactctt gatattggtt accaataaaa gtaggaaaac agggaagacg accatcaaat
    17161 aagaagcgtg cagaggctct tgtgaaaaga aaagtaaaat caaacctaaa attaccacaa
    17221 gacttgcagg aaccgaaatg acgtatagtt taaagggttt ggattgaaag agacctaaaa
    17281 agatacaaac cacaaatccc aaaccaaggg acaacaagcc ataaaaaaac atattctcta
    17341 aaattttaga agtaaaatca aagcgaatac tgtcaatagg ataacgaata ccactaatcg
    17401 catccccaaa acttcctgtt gcagcactat agtaggcagt tggataaaag acaagtgaaa
    17461 aacctaaagc cactgcaaga aactgataaa acccatgcgc aaagcgtcta tgcccaaggt
    17521 taaagaccaa caagcctaaa ctcactacag caataaacag gagtgatgat aagggagcaa
    17581 agaaaaatcc gcctgccaaa gctaacccaa tccgtacaaa tcccttatca tggcttggat
    17641 tgcttaggta agccgcaact aaactaaagg ctgcgaataa gaaaggaagc gctaaaagag
    17701 tcgcatagcc tccaccaaaa gcaagacctg taactagcat gtaaaaaata gtcaccagat
    17761 gtccagcttg gtctccttgc tctgtcaagg tgtccgctga tctaaaaagg aaaaatcctc
    17821 ctgctaccaa ggctaaccac tcaaagatgg caaagaaaaa tccgccctga ctcacgtaag
    17881 tcagcaaata ataaagcaaa ccttgacttc cataatagtc gctgtaaatc ttccctgtct
    17941 gatgaagcgc ccaacctgca taaaaatcct gcacttcttg tgcactcatt aagtcgagta
    18001 atagcggtac tcctagagtt atccccgtta caagcgtact ccatagtaaa attttcacca
    18061 aaggaagacg acttgattca cgatgatgcg attcttgctc gatttggtat tctagaggtt
    18121 cacgattctc cttatgaact tcttctactc taccatacac actcatatcg tttctcctgt
    18181 tcaatttatc tgtcttagta tatcaaaaag tcctaggatt gtcagcttgc gatggctgtt
    18241 tgagtgattt tttgcatagt ttcacaaagg tttcaatttc ccgaaagcgg tgtaaatgtg
    18301 tctgtttgaa ctcaatcata tcattcactt cttccttagt tagcatgaat tcccctcctc
    18361 tttctttcta ttcgtaaaag acaagaaaaa taggtcgggt ttgtatccta agttctagat
    18421 ttcttataag ataggggcga atagctgggc gatttctttt acaagctttt gataccagct
    18481 cgttttgata gaatgaggat agacttcctg agaatctgca aatatatttc gaaaatctcg
    18541 ggcgatttcc cttatagaag gagttttata gagtaagact gcattttcat aatggtgtac
    18601 caagctccgg tagtcgagat tgattgtccc caccaccgca aaatcttcgt ctaccaacat
    18661 ctgcttacta tgaataaaac ctggactata ctcataaatc cgaacaccag cagaaagaag
    18721 gtcgggataa gctcctctcg tgactaactg aatgaacttc ttatctggta tgtaaggggt
    18781 gataattcga acatcgaccc ctctcatagc tgcatttttg attgtctctg ttaaatcata
    18841 atctataatc aaataaggtg tcgtaatata gaccgattcc gttgcttgat tgattaaact
    18901 ctgataaact tttttcccta cctgcgctcg aaaaattggc ttgggtccac ttccgtatgg
    18961 aatggttaaa ccgtcactcg ggatagaatg attttctaaa tgatattgat caaaatcact
    19021 aatttctcct cgattaatgt accaagtggt caaaaataag cgtgtcaggg cttttactgc
    19081 tagtccgtct aagcgaattc cactatcctt ccaataacca aatctctcga cgtggttaat
    19141 gtactcatct gccagattga ccccaccagt ataggctatc tgaccatcaa caatcaatat
    19201 ttttctatga tctctgttat tataagccac tgtcaaacga ggaataactt tattgaattt
    19261 atgggcctcg atgcccagct gacgaagtcg atgtgcataa tctcctgtta aagtagccat
    19321 acagccgata tcatcataga gcatcttaac ctctacaccc tgagctacct tttgctctag
    19381 tatatctagt atgcgattcc acatcaaacc ttcttctata atgtaatatt ccaagaaaat
    19441 aaatttctca gcctttttaa gatcttctac catctttttc cacatagctt ctccgttagg
    19501 aaaaaatgta gaggcagttt gatcatagat gtcagcattg gtatccatac tcaataagga
    19561 cttgatgact ccataagctg ccttgtcact ttcttttaat ttctctttta gtagctggct
    19621 atttgcttct tggaaatgca tagagcctag cttcttcagt tgtttgattt cttttttgga
    19681 caatcgcctt tcaccaaaca tcagatagag taagggacca aatactggca caaaggctac
    19741 taacaaccag gttaccttat tctcaggagt cgtattacgg ttgactatcg aaatgattgt
    19801 gatgatactc agtagaatga ggacagtaat ccataaaatg ggagccatgc gtcctaaata
    19861 aagaaagaga ccaaaaacaa gacaaagttc aagtagcata atcgaaagac taaagccata
    19921 cttggacatc aataattgaa atttcctata tttcatatcc cctccttgat agtttgaatg
    19981 ctaaaaacaa gtaattgata ctagtataac gcaggtattc ggtagaaggc aagtatttat
    20041 gattattttc taggtaaaag taaaaaggct gaaaaatcca gccctttcta cttgcatagt
    20101 cttatttagt taaaacgatt tggtccgatg ggtctctatc catatcatct acgacgattt
    20161 gattaccgtt tacagtgtaa attttgacat catcgccaat aatcatgcgt tgatttgctg
    20221 aatcaaatgt aacctgtttg actttctgat ccccgtcaga ttcgagctca gtccatgtac
    20281 cagtcgttcc agttaccact aaagtgatac ggtctccgtc atcctgacca gtataagtcc
    20341 catcaatatc ggtcggttga gcaacaggtt ggttttgtac tggagccgct tgattttggt
    20401 tacctcctgc atttgcagta ttggtattct gttgagcagg ttgttgagca ggctgttgga
    20461 cctgctgctg agcaacaggc tgttgaacct gttgagctct ttgtgaacaa gctactaaga
    20521 gactaaaact tgctagagaa gcaagagaaa gtgtgaatct ttttaatttc atgatgaatt
    20581 tcctttctgc taccaattta gagaaatttt ctctaaccag caattcccct agtataacaa
    20641 gttcaaacaa gggggtcaat ttatctgctc acggtccagc aggtagcccc gtacttctga
    20701 gataaaatag agagaccctg taacgaacag caagtcttga gcgtctgccc tttcttcgaa
    20761 actgctgata aattctcggc aagaagaaac tatatcgtaa cctgtcacat ccctttcgtc
    20821 caaagccccc tgatagtcaa agccggtcac cttgagttcc acctgaggca atttttcagt
    20881 caggtaacct aacatccctt gataatcctt ccgtttcaag gctccaaaaa ggatttgagg
    20941 tcgatagcct tcctgctctt tttctttgat aaactcaacc aagcgagtca aggcagggag
    21001 gttatgagca ccatccaagt aaatctgtgg gcgaatacgc tccaagcgac cagcccaatg
    21061 ggtctgttcc aaggcctttc ttacagcctg ttcatcaaca gcttcctttc cttctcccat
    21121 aaaaagaaga aaagtttgca acgccaaggc tgcattctcc tgctgataga ctccttctaa
    21181 gcctatgttc agctgtgaaa aatttagtaa agagcttgaa aaatcaccat tcagcattaa
    21241 aaaatcttga cctgcctgat aaaggttaac agctaaagat tcggcttttt tctgacagac
    21301 aagcctagct tctggaggca atttcgcaat cactgccttc ttaccagcct tgaaaatacc
    21361 agctttctgc tctgcaattg cttctagact atcacccaag gtttcttgat ggtcaagccc
    21421 aatggaggtg atgacagcaa gctctccagt taccacattg gtcgtgtcaa gtaagccacc
    21481 aattcccact tctaataaaa ccaaatccac ctcttgctcc ctaaaataaa gaaaagcaac
    21541 caaggtcagc atttcaaaaa aggacaactg gtcaggagtt tgcagaagcg ttttctccat
    21601 ctccttgacc tgatcagcca aacggataaa gtctgcgtct gctataggtt gcccattaat
    21661 gcagattcgg tcattgatag agacgatatg aggggaggta aaggtcgcaa cttttttgcc
    21721 atgccccata aataattccc tcataaaagc aatggtagat cctttcccat tagtccctgt
    21781 tacgtggata atagggtaag actgctcagg atttcctaac aaatccaccg cttgctgtat
    21841 tcggcccaaa cctgatcgaa aattcaaacc aatccgacta tgaagccatt cttctacttc
    21901 aaacatacac atctccttga caaaagtcca atcaattatc gcattaaagt atggttacta
    21961 ataaaaacaa ggccaggatt ttcgtcccga cctcttacct ggttagctaa taactagcca
    22021 ctatgaatgt gaatatgggc taaaaacatc cactagatgt tccaactctt ccccatttct
    22081 gggagttggg ctgatacagt ctcccagact gtatcactcc tccataaagc tgttgaagac
    22141 ttcttcaatc atgttccatt cgtcttctga gtcttctggg attggttgca attcgccttc
    22201 tgttccatct tcattttcaa tgaatgagta agcttggatt tcaacttgtc cgtcttcgtc
    22261 ttcttctgcg ttaactggta ctagaagaac atagttttta ccaaattctt cttttccatc
    22321 aattgtcaaa aggatttcaa acaaggtttc atttccttgc tcatctacta gtgtgattag
    22381 ttcacgttct tcgtggtcgt ggttatgatc gtgtgacata gcctctcctt tatattaaaa
    22441 ttttctatct aaataatttt gtaaaatcag ctgagctgct aacttatcaa tgactttctt
    22501 gcgcttattg cgactgatat ctgcttgttc aatcaacatg cgctcagcag ccactgttgt
    22561 caagcgttca tcctgatagt ctaatggtaa accaaaaaac tcttctagct ttgctccgta
    22621 ggcttgacta gcttctacgc gcggtccact tgtattgttc atgtttttag gcaagcccac
    22681 tacaaatcgt tccaccttgt aagtatcaac caattcctta acgcggtcaa aaccaaattg
    22741 gccttgttct tcatttatct ggatgatttc aagcccttga gctgtaaaac caagcggatc
    22801 gctaatcgcc acccctaccg tttttgaacc gacgtccaat cccataattc tcataggtta
    22861 tagatcgact ccttgtcctt tgaggtagta gcgaaccaat tcctcaacga tttcatcacg
    22921 ctcatactta cggatttgat ttcgtgcatt attataacga ggaacgtagg cagggtctcc
    22981 actcaatacg taacctacga tttggttaat tgggttgtaa cccttatcgt tcaacgaagc
    23041 ataaacatct gtcaaagttt cgctaatttc ttttttattg gaatcgtcca atttaaaacg
    23101 tactgtttct tcagtaaatc ccattctaac accctctttc cttagaatag taccattata
    23161 gcataattcc ttaccttcta caattcaggc agtctattta tttggatttt ctattgttct
    23221 gtcgcgccat ttgccaatct atctgaaata tatttgcttg gttcattttt caaaagattt
    23281 tccaaaccaa tattcttcag atgttccaac tgggaagcct tcttgacatc cagaacttga
    23341 aaatcaaaac tagtcgttgt ttgaagttcc gttgcgctca atagttttgt ttcaagtttg
    23401 aaacctgcca atttacgagc ttcaatgata gacttatcct tctcctccgc ttcaagaaga
    23461 gctttttgag tttcctccac tccatgttgg tcaatataag tcttcaactc atcagagact
    23521 ggacgttttt gttggatagt tagactcaaa aaagtcttgt ccttgtatgt aatggtttgt
    23581 gtctgctggc taccatcatc tgacttgggc aagaccaaag tcttagttac aactgtattc
    23641 ttctcagcat tttcaataac tggcaatgcc gactgaagcg tatctttttc tgtttttgta
    23701 gctggtccag tttctttttt ctgtccgcaa ccaaccagga caaaaaggaa agctagacta
    23761 acaagaacta tttttttcat ttctttcttc tttctttttg aaattaaaat agaataagac
    23821 tgggaagtgc tcccagcctt gatgtttata gagctgcacg caaacgtgct tctgcatttt
    23881 ctacattacg gacagagcgt ggtaggaagg cacgaatatc gtcttccttg tagccaactt
    23941 gcaggcgttt ttcatctaca aggattgggc tctttaaaat tctcggtgtt tccataatca
    24001 gattgagaac ttcattgaca ctcaaatctt caatatccac tccaagggct ttggcatagc
    24061 gatttttaga cgaaacgatg ctggctattc cgttatctgt tttggttaga atatccagta
    24121 attcttctct cgtaattcct tctttaccaa ggttttgttc tttataactt aactggtggg
    24181 cattgagcca ggtttttgct tttttacagc tagtacaact tgagactgta taaattttaa
    24241 tcatgtacct acccctttcg ctacatgtta ctatcagttt agtctattat accataaaaa
    24301 acatccgact tgcgacctat ttttaat
//
LOCUS       DAVBCA010000029        23965 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.029, whole genome shotgun sequence.
ACCESSION   DAVBCA010000029 DAVBCA010000000
VERSION     DAVBCA010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23965)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23965)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23965
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.029"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(255..2513)
                     /locus_tag="VQU19_001134"
     CDS             complement(255..2513)
                     /locus_tag="VQU19_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET2480390.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(2742..2972)
                     /locus_tag="VQU19_001135"
     CDS             complement(2742..2972)
                     /locus_tag="VQU19_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HET2480391.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            3162..3845
                     /locus_tag="VQU19_001136"
     CDS             3162..3845
                     /locus_tag="VQU19_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2480392.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSEIVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            3845..4579
                     /locus_tag="VQU19_001137"
     CDS             3845..4579
                     /locus_tag="VQU19_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET2480393.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKVIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDIAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            4733..5590
                     /locus_tag="VQU19_001138"
     CDS             4733..5590
                     /locus_tag="VQU19_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HET2480394.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGYRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLTHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASHITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            5732..6604
                     /locus_tag="VQU19_001139"
     CDS             5732..6604
                     /locus_tag="VQU19_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HET2480395.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLMTVGTDRENIPALHSHLPEPMAFSLQDQQLLKEQLEKAEVILLGPGL
                     GDNAFGEDLVKQVFAGLKQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQERVSKDKLV"
     gene            6886..7569
                     /gene="rpiA"
                     /locus_tag="VQU19_001140"
     CDS             6886..7569
                     /gene="rpiA"
                     /locus_tag="VQU19_001140"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HET2480396.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            7583..8794
                     /locus_tag="VQU19_001141"
     CDS             7583..8794
                     /locus_tag="VQU19_001141"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HET2480397.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            8796..9338
                     /locus_tag="VQU19_001142"
     CDS             8796..9338
                     /locus_tag="VQU19_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HET2480398.1"
                     /translation="MTRYALLVRGINVGGKNKVVMAELRQELTNLGLEKVESYINSGN
                     IFFTSIDSKAQLVEKLETFFAVHYPFIQSFSLLSLEDFEAELENLPAWWSRDLARKDF
                     LFYTEGLDVDQVIATVESLELKDEVLYFGKLGIFWGKFSEESYSKTAYHKYLLKVPFY
                     RHITIRNAKTFDKIGQMLKK"
     gene            9354..10163
                     /locus_tag="VQU19_001143"
     CDS             9354..10163
                     /locus_tag="VQU19_001143"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HET2480399.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            10639..11619
                     /locus_tag="VQU19_001144"
                     /pseudo
     CDS             10639..11619
                     /locus_tag="VQU19_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855254.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
     gene            11644..12156
                     /locus_tag="VQU19_001145"
     CDS             11644..12156
                     /locus_tag="VQU19_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HET2480400.1"
                     /translation="MSAQITINHKKARYVRIELEGYNALSLAEVEVFRFIATNAETAT
                     QVSKPVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVPVDKDGNQVVRSHSWEGNGR
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPISAQPHRKITHWGTTL
                     NSKVSDDDVL"
     gene            12803..13513
                     /gene="deoD"
                     /locus_tag="VQU19_001146"
     CDS             12803..13513
                     /gene="deoD"
                     /locus_tag="VQU19_001146"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HET2480401.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLDDAVCFNEVRN
                     MFGYTGTYKGHCVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKKLGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(13536..14060)
                     /locus_tag="VQU19_001147"
     CDS             complement(13536..14060)
                     /locus_tag="VQU19_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HET2480402.1"
                     /translation="MKIAIIGYSGSGKSTIAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     CEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFSPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFEWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(14113..14349)
                     /locus_tag="VQU19_001148"
     CDS             complement(14113..14349)
                     /locus_tag="VQU19_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HET2480403.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(14417..15337)
                     /locus_tag="VQU19_001149"
     CDS             complement(14417..15337)
                     /locus_tag="VQU19_001149"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HET2480404.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEKKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVESFAHQVWISINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            15527..15931
                     /locus_tag="VQU19_001150"
     CDS             15527..15931
                     /locus_tag="VQU19_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480405.1"
                     /translation="MKILKRYILELCFILSFALPFIKGTNADNGRCFVETYYGFTFLM
                     EHAIVTAVFIYSFLIAFLLKKRWAKWIAAGSYCFLVLWIATEGYFFRMSLEDLIRLWT
                     SLEILTQTYQLGFYLNILLGILLIIKYFKVKQ"
     gene            16147..16728
                     /locus_tag="VQU19_001151"
     CDS             16147..16728
                     /locus_tag="VQU19_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET2480406.1"
                     /translation="MYYAENPDAAHDIHELRVDLLGQKMTFLTDAGVFSKKMVDFGSQ
                     LLLKCLDVNQGETVLDVGCGYGPLGLSLVKVYGVQATMVDINTRALDLARRNAEKNNA
                     KATIFQSNIYEQVEGHFDHVISNPPIRAGKQVVHEIIEKSKDFLETGGDLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            16725..18002
                     /locus_tag="VQU19_001152"
     CDS             16725..18002
                     /locus_tag="VQU19_001152"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HET2480407.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLVEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIRGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVHQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDALDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            18020..18682
                     /gene="deoC"
                     /locus_tag="VQU19_001153"
     CDS             18020..18682
                     /gene="deoC"
                     /locus_tag="VQU19_001153"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HET2480408.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYDFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKIVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVTLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            18669..19058
                     /locus_tag="VQU19_001154"
     CDS             18669..19058
                     /locus_tag="VQU19_001154"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HET2480409.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIE
                     NASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMAEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            19148..20200
                     /locus_tag="VQU19_001155"
     CDS             19148..20200
                     /locus_tag="VQU19_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HET2480410.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALNNAVKDAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            20344..21879
                     /locus_tag="VQU19_001156"
     CDS             20344..21879
                     /locus_tag="VQU19_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2480411.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            21872..22930
                     /locus_tag="VQU19_001157"
     CDS             21872..22930
                     /locus_tag="VQU19_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2480412.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            22933..23889
                     /locus_tag="VQU19_001158"
     CDS             22933..23889
                     /locus_tag="VQU19_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2480413.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGIIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
BASE COUNT         6956 a         4329 c         5459 g         7221 t
ORIGIN      
        1 tgcaatacct tttacgaggc tcttttgtcc tgctcttgtt tcaattgact atagcagatt
       61 gaaataagat gagaacaaat cgattgggaa agtaaaatta atttctataa atgttttagc
      121 aattgtttcg tactatttca gattcagtct actatatatc ataatggaca aagggcaagc
      181 tgtcaagaaa ttacagttat tttagtaaaa aaagaagcag aaaaatttaa ttttctactc
      241 cttttctata ggatttattt ttctttttca gaacttttaa cttcagcttt tttggcagat
      301 ttaatctgaa tgtttccctt gctagtcata actgctttga gatctttttc gcttggattt
      361 tcaaggtagt agtcagtgat tgtgtcctca atatagtctt gaatagtccg acgaagtggg
      421 cgtgctccca tttttggatc ataacctagg tcaaccaact tttccttgac cttgtcagtt
      481 acatccaaac gaatgttgtt gctagagagg cgcttgttaa catctgctag catgagctcg
      541 acaatctgaa ggaggttatc cttgctgaga gccttaaatt cgataatgcc atcaaaacgg
      601 ttcataaact ctgggctaaa gaagttaccg agttcaccga ggacagaatt ggtacgtcct
      661 tctctagcag caccaaatcc aacgctagct tcggtctttc ctgtacctgc atttgaggtc
      721 atgataatga tggcatcctt gaagctaacg gtgcgtcctt gcccgtctgt caaacgacca
      781 tcgtccaaga cttgaagaaa catgtgcata acatctgggt gagctttttc cacttcatcg
      841 agaaggatga gagaatatgg attgtggcga actttttcag ttaattgacc agcctcatca
      901 tagccaacat aacctggagg agcgccgacc aacttagcca cactatgttt ttccatgtat
      961 tcactcatat caaagcgaat catactatca gcagaaccaa aaagttcgat agccagttgt
     1021 ttggaaagtt ctgtcttacc gacaccagtt ggcccaacga agaggaagct tccgattggg
     1081 cggttagggg taccaagtcc gacacgatta cggcgaatag ccttggcaat cttatcgact
     1141 gcatcatctt ggccaataac atgagacttg agatcttcgg ctagatggat gagttgagat
     1201 tgttctttct ctttcaaatc accaacaggg atattggttt tctgctcgat aatgtgctca
     1261 atagttttct cgctgatgat aggagtatcc tggtctgtga tctttttctt ttgcatttcc
     1321 ttatacttgg caatctggtc gcggaagtag gccgccttct caaaatcttc ttctcgtgta
     1381 gcttgagact tgagattttc agcctcaatc aagcgctgat caattacttt aggatccaca
     1441 aaattcaagg tcaagttcat cttagaacca gcttcatcta ggaggtcaat ggccttgtca
     1501 ggcaagaagc gatcttggat gtagcgattg gaaagagttg cagctgcttc aatcgcagca
     1561 tctgtatatt gaacgtggtg gtaatcttcg tatttctttt gaatcccttt gagaatagtg
     1621 attgtttcgt ccaccgttgg ttcatcgact ttaacaggct gcatacgacg ctcgagggca
     1681 gcatcctttt caatgatacg gtattcattg agggtagtag caccgactag ttgcagttct
     1741 ccacgagcaa gggctggctt gaggatattt cctgcgtcca tattaccatc actcgcagaa
     1801 ccagcaccaa caatttcatg gatttcatcg ataaagagga tgatgtcttc acgtttgcga
     1861 atttcttcca tgagtttttg catgcgttct tcaaattgtc ctcgaatccc cgttccttga
     1921 actaagctaa ccacatccag acggatgact tgtttacctt ggagtttatg tggcacatcg
     1981 ccatcgacaa ttttctgagc tagaccttcg acaacggccg tttttccgac accaggttca
     2041 ccgataagga caggattatt cttggttcta cgattgagaa tctcgatgac acggataatc
     2101 tcatcgtcgc gcccaataac ggggtcaatg tctccacgac gggcaatttc agttacatta
     2161 ataccaaatt cttccagcag gcctttttct tggctaggtg gcggagtttg agcagatcca
     2221 cgattttggg aaccataacc gccgtttcca ccgtaacctc cacctgattg ggttggggga
     2281 ataggaggag tattgctaga aggtctgaaa ttgtttagat cattgaagaa atcaccaaag
     2341 ggatcgaagt cacgattgtt cagatccgtc atacctttga agaggctatt gttaggatct
     2401 gttttgataa tcttatagca gttttgacag aggtcaattt gtttttgttt tccattgaga
     2461 ttggtgtaaa gatgaattgt tgagtcgtta attttacagt tttgacaaag catacatcta
     2521 cctcatttct ttctttagcc tgacttgttt aaaggtcaaa aatagtcaaa ttctatactc
     2581 tcattataac aggattgggg tgtaaagcaa gtaaaaagat tgaagctttg agaagttgtt
     2641 acaatgaaaa tttttgtgaa tttggactat aaaaaaatcc tatttgtgag acaaaaagga
     2701 ttttacttag acatgcaggg acaatcccag cttgttttag attagtagag aagttcgtaa
     2761 atttccattg cgattaagtc aatgctatca aacgtatacg tttcgcgatc ttctacgtca
     2821 cgaagggtaa agattgggcc gttttcttcg tcgtggctgt acgcaacttc tgcaacaaca
     2881 actccttcgc gttcaaaatt acgttttaaa tttccgccat cgtttgccat tgcttcaagg
     2941 cggttgatga ttctaaccaa atgtgattcc attttgattc tccttcattt cttatcgtta
     3001 ctattttacc ataaaggagg ccaacttgac tagaaaaaac taagatttct cgctaattct
     3061 gctagtttaa agatttttaa ataaattgga taaaaaattt aaattttaat tcaaaacatg
     3121 ttataatcat acagtattct attttagaaa gcagtgtgac tatgaatttt tcttttttac
     3181 ctaagtattt accttatttt aactatgggg ctgttgtgac gattcttatt tctatctgtg
     3241 ttatcttttt gggaactatt ttgggtgttg tcttggcttt tgggcaacgt tcaaagttta
     3301 aaccgcttgt ttggttggcc aacttgtacg tttggatttt ccgtgggaca ccgatgatgg
     3361 ttcaaattat gattgccttt gctcttatgc atatcaatgc tccgactatt cagattggaa
     3421 ttttaggtgt tgatttttcg cgtctgattc cagggatttt gattatctct atgaatagtg
     3481 gtgcttatgt ttcggagatt gttcgtgccg gaatcaatgc ggttccaaaa ggtcagctag
     3541 aggcggctta ttcgctaggg attcgtccta aaaatgcgat gcgttatgtg attttgccac
     3601 aagcagtcaa aaatatcttg ccagcattgg ggaacgaatt tatcaccatt atcaaggaca
     3661 gctccctctt atcagctatt ggggtcatgg agttgtggaa tggggctaca acagtttcta
     3721 caacaaccta tctaccttta acaccacttt tatttgcagc attttactac ttgattatga
     3781 cctctattct gacagtagcc ttgaaagctt ttgaaaaaca tatgggacaa ggagataaga
     3841 aataatgaca gaaaccttga taaaaattga aaatttacat aaatcttttg gaaagaatga
     3901 agtattgaag ggcatcaacc tcgagattaa aagaggagaa gttgtcgtta tcatcggtcc
     3961 ttcagggagt gggaaatcta ccttgcttcg ctctatgaat ttgttggagg aagcaaccaa
     4021 ggggaaggtt atctttgagg gagtcgatat tacggacaag aagaatgacc tgtttgccat
     4081 gcgtgagaag atgggcatgg ttttccaaca atttaacctc tttcctaata tgactgtgat
     4141 ggaaaatatt accttgtcac ctatcaagac taaaggtgaa agcagggaag ttgctgagaa
     4201 gagagcccaa gagcttttgg aaaaagttgg tttgccagat aaggcagacg cttatccaca
     4261 gagtctgtcg ggtgggcaac aacaacggat tgccatcgcg cgtgggttgg ctatggaacc
     4321 agatgttttg ctctttgacg aaccaacttc agccttggat cctgaaatgg taggtgaggt
     4381 attggctgtt atgcaagaca ttgccaagtc agggatgact atggttatcg taacacatga
     4441 gatgggattt gcccgtgagg tggcagatcg tgttatcttt atggcagacg gtgtggttgt
     4501 tgaagatggg acacctgagc agatttttga acaaacccaa gaacaacgga ctaaagattt
     4561 cttgagtaag gttttataat ctattttaaa atttcaagac aagattagtg aaaagttcaa
     4621 ccagagcttt ttcttatagt ttgaaactat aggataacct aggaaagaag tgttagaggg
     4681 cactagcagt ttttggtata atggaagata tttgaaagaa aagagaagtg atatgacaca
     4741 gattattgat gggaaagctt tagcggccaa attgcagggg cagttggctg aaaagactgc
     4801 aaaattaaag gaggaaacag ctctagtgcc tggtttggta gtgattttgg ttggggataa
     4861 tccagccagc caagtctacg ttcgcaacaa ggagaggtca gctcttgcgg ctggttaccg
     4921 tagcgaagta gtgcgagttc cagagaccat tactcaagag gaattgttag acctgattgc
     4981 taaatataat caggatccag cttggcatgg gattttggtc cagttgccat taccaaaaca
     5041 tatcgatgaa gaggcggttt tattagccat tgacccagaa aaggatgtgg atggtttcca
     5101 tcccctaaac atgggacgtc tttggtctgg acatccagtc atgattccct cgacacctgc
     5161 aggaattatg gaaatgtttc atgaatatgg gattgacttg gaaggtaaaa atgcggtcgt
     5221 aatcggtcgt tcaaatatcg ttggaaaacc tatggctcag cttcttttgg ctaaaaatgc
     5281 gacagtaacc ttgacccact cacgaactca taatcttgcc aaggtggctg ctaaagcaga
     5341 tattcttgta gtcgcaatcg gccgcgccaa gtttgtgact gctgactttg tcaaaccagg
     5401 tgcggttgtc attgacgttg ggatgaatcg agatgaaaat gggaagctct gtggagatgt
     5461 tgattatgag gcagttgcac cacttgctag ccatatcacg ccagtccctg gaggtgtcgg
     5521 tcctatgacc attaccatgc tgatggagca aacttatcaa gcagcacttc ggacattgga
     5581 tagaaaataa gagaagcatt cgattaatag agtgtatttt ctatagctat atctaaaatg
     5641 gcagaaatga atattaaatt ttagatataa gattacaaaa ggaggtctgc gtctcctttt
     5701 tattgtataa taaaagtgag aggaaaaaag gatgaaagtg attaatcaaa ccttattaga
     5761 aaaagttatt attgaacgtt ctcgttcaag tcataaagga gattatggtc gtctgctgct
     5821 gcttggtggt acttatcctt atggaggtgc catcatcatg gctgctttag cagctgtaaa
     5881 aagcggtgca ggattgatga ccgttggaac ggacagggaa aatatcccgg ctctgcacag
     5941 ccatttacct gagcctatgg ccttttctct tcaagaccag caattgttaa aagagcaatt
     6001 ggagaaggca gaagttatct tgctggggcc tggtttagga gacaatgctt ttggagaaga
     6061 tttagttaaa caggtctttg ctggcttaaa acagaatcag attttgattg tagacggagg
     6121 tgccttgacc attcttgcta ggacaagttt gtcatttccc tcaagccagc ttatcctaac
     6181 tcctcaccaa aaagaatggg aaaaattatc tggaattacg attgaaaagc aaaaggaaga
     6241 tgcaacggct agtgttctga cttccttccc tcaaggaaca attttggtgg agaaaggccc
     6301 agctactcgt atttgggaag ttggccaatc tgattattac cagttacagg ttggtggtcc
     6361 ttatcaggcg actgggggaa tgggagatac tctggctggg atgatcgcag gatttgtagg
     6421 ccaattccga caggccagtc tctacgagcg tgtggcagta gcgacccatc ttcattcagc
     6481 catagcccaa gaactatctc aagaaaatta tgtggtctta ccgacggaaa tcagcaggta
     6541 tcttcccaaa ataatgaaaa ttatttgtca acaagagagg gtaagcaaag ataaacttgt
     6601 ttaaaataga cagataaatc tacttccttc tcttaattta tgattcttga aatgcgcctg
     6661 ctttaaggct aaactagacg tatcaaagtt aagagtttgt ttttgtaact ggaaagagat
     6721 gaacaaatca aatacataaa agataaactc atttttattc gttttgtaaa aataaaatgc
     6781 atatttttaa agaaagattg atgaaaaatg tagatttgat gtttttactt gaataaaaag
     6841 cggtttcata gtaaaataag aactgagaat gatggaggta aatcggtgga aaatctgaag
     6901 aaaatggcag gtatcaaggc tgctgagttc gtgagcgatg gaatggtcgt tggacttgga
     6961 acaggctcga ctgcctatta ttttgtcgaa gaaatcggtc gtcgtatcaa ggaagaagga
     7021 ttgcagatta cagctgtaac aacttctagt gtgaccacta aacaggcaga aggccttaat
     7081 atcccgctca agtctattga ccaagtagac tttgtcgatg tgacggttga tggcgcggat
     7141 gaagtggata gtcagtttaa tggaatcaaa ggcggtggtg gtgcccttct catggaaaag
     7201 gtggtcgcaa caccatcaaa agaatacatt tgggtggtgg atgaaagcaa gctggtcgaa
     7261 aaactaggtg cttttaaatt gccagtagaa gtggttcagt atggtgcaga gcaggtcttt
     7321 cgtcattttg aacgagctgg ctacaaacca agtttccgtg aaaaagacgg tcaacgtttt
     7381 gtgacggata tgcagaattt tatcattgac ctcgccttgg atgtcattga aaatccaatt
     7441 gcttttggac aagaattgga ccatgtcgtt ggtgttgtgg agcatggttt attcaaccaa
     7501 atggtggata aggtaatcgt tgctggacga gatggagttc agatttcaac ttcaaaaaaa
     7561 ggaaaataga agggggcata agatgtctaa atttaatcgt attcatttgg tggtactgga
     7621 ttctgtagga atcggtgcag caccagatgc taataacttt gtcaatgcag gggttccaga
     7681 tggagcttct gacacactgg gacacatttc aaaaacagtt ggtttgaatg tcccaaacat
     7741 ggctaaaata ggtcttggaa atattcctcg tgaaactcct cttaagactg tagcagctga
     7801 aagcaatcca actggatatg caacaaaatt agaggaagta tctcttggta aggatactat
     7861 gactggacac tgggaaatca tgggactcaa cattactgag cctttcgata ctttctggaa
     7921 cggattccca gaagaaatcc tgacaaaaat cgaagaattc tcaggacgca aggttattcg
     7981 tgaagccaac aaaccttatt caggaacggc tgttatcgat gattttggac cacgtcagat
     8041 ggaaactgga gagttgatta tctatacttc agctgaccct gttttgcaga ttgctgccca
     8101 cgaagacatt attcctttgg atgaattgta ccgtatctgt gaatacgctc gttcgattac
     8161 ccttgagcgt cctgcccttc ttggtcgcat cattgctcgc ccttatgtag gtgaaccagg
     8221 taacttcact cgtacggcaa accgtcgtga cttggctgta tctccatttt ccccaactgt
     8281 tttggataaa ttgaatgagg ctggtatcga tacttatgct gtgggtaaaa tcaacgatat
     8341 ctttaacggt gctggtatca accatgacat gggtcacaac aagtcaaata gtcatggaat
     8401 tgatacacta ttgaagacta tgggacttgc tgagtttgaa aaaggattct cattcacaaa
     8461 cctagttgac tttgatgccc tttacggcca tcgtcgtaat gctcacggtt accgtgattg
     8521 cttgcatgag tttgatgaac gcttacctga aattatcgca gctatgagag agaatgacct
     8581 tctcttgatt actgcggacc atggaaatga cccaacgtat gcaggaacgg atcacactcg
     8641 ggaatatatt ccattgttgg cctatagccc tgcctttaaa ggaaatggtc tcattccagt
     8701 aggacatttt gcagatattt cagcgactgt tgccgataac tttggtgtgg aaactgctat
     8761 gattggggaa agtttcttag ataaattggt ataagatgac gcgctatgct ttgctggtga
     8821 gaggtatcaa tgttggtggt aagaataagg tcgtcatggc ggagcttcgt caagaattga
     8881 caaacttggg actggaaaag gttgagagct acatcaatag tggcaatatt ttctttactt
     8941 cgatagattc caaagcccaa ttggttgaaa agctagagac tttctttgca gtccattatc
     9001 catttattca gagcttttct ttactgagtc tagaggactt tgaggcggaa cttgaaaatc
     9061 taccagcttg gtggagcaga gacttggcac gaaaagattt tctcttttac actgagggtt
     9121 tggatgtgga ccaagtcatc gcgacagttg aaagtttaga gctgaaagat gaagtgcttt
     9181 attttggaaa acttgggatt ttctggggga aattttctga agaatcctat tctaagactg
     9241 cctatcataa gtacttgctg aaggtgcctt tctaccgcca cattactatt cgtaatgcta
     9301 aaacctttga caaaattggt caaatgctaa aaaaataata aaggagacac acaatgacat
     9361 ttttaaacaa aatccatgaa actgctactt tcctgaaaga aaagggaatt gcagcccctg
     9421 agttcggtct aatccttgga tcaggacttg gagaattggc agaagaaatc gaaaatccag
     9481 ttgtagtaga ctatgctgag attccaaact ggggccgttc aacagtagtc ggtcatgctg
     9541 gtaaattggt atatggtgaa ctggcaggtc gcaaggtctt ggctcttcaa gggcgtttcc
     9601 atttctatga agggaatcct ctggaagtgg tgactttccc agttcgtgtg atgaaagttc
     9661 ttggatgtga aggtgttatt gtaaccaatg cagctggcgg tatcggattt ggtcctggta
     9721 ccttgatggc tatctcagac catatcaaca tgacggggca aaatccattg atgggtgaaa
     9781 acttggatga ctttggccca cgtttcccag atatgtctag ggcctacaca ccagaatacc
     9841 gtgccactgc ccatgaagtg gctaaaaaac ttaatatcaa gcttgatgaa ggtgtctata
     9901 tcggagttac tggtccgact tatgaaacac cagcagaaat tcgttcctat aagacactgg
     9961 gagcagatgc agttggtatg tctacggttc ctgaagttat cgtggcagcc cactctggct
    10021 tgaaagttct gggaatttca tgtatcacta actttgcggc cggtttccaa gaagaactca
    10081 atcacgaaga agttgtagaa gtgactgaac gtgttaaagg tgatttcaaa ggcttgctta
    10141 aagcgattct tgctgaattg taagaaaaaa gatttaaaag ggggagtgcc tctgtttttt
    10201 caggattgac tgcctatccg gattaaagaa gaaacagagg aatactatga gcttcttcct
    10261 gctcttataa ctgaaagaag cggaagaata ggtatgtctg atctgatagc cagcattgtg
    10321 aaagacaaga ttctaggata ctagcattag cttcctagcc aagcagacta gtatgataag
    10381 gagagatgag aatgaattga ctttctgaat ttctcagtct tatcatatat agcacaatga
    10441 gatttcgctt gagtctgctt gtaaataaac gaaaagaaag ataagaaata atgaaaattg
    10501 gtcaacgaat tatgcgcttt ggcataaaaa attaagtatc ggagttgtat ctgttgtagt
    10561 cggctttgat ttctagctcc agctggaatt tcagccaatg aagtaaagca agatgtaaca
    10621 tctgaagtgg taataggtgt gctagattct aaggaggaat tgaaagagtc agaaaatgat
    10681 gctccaaaac tagaaactcc tcttagagag gagccaagac tagctcctca aacgcttccg
    10741 gaagcaagtg aagttcttga aaacaaaagg gaagagtcaa aagtagagat aacataacca
    10801 gctcaagcgg atgatatccg caaggttgtt ggggaattag ccaaggatat aagtattact
    10861 aagttgtata tgacaggtca ttctcttgga tgttacctag ctcagattgc agcggttgaa
    10921 gcttaccaaa aatatcctga tttttataac catgtattga ggaaagtgac aactttcagt
    10981 gctcctaaag tgattacttc cagaactgtt tggaatgcta agaatggttt ctgggatgtt
    11041 ggtttggaaa gtcgtaaatt agctgttagt ggaaaaatta agcattatgt ggttgataat
    11101 gacaatgttg tgactccctt gattcataat aatcgtgata ttgttacatt tacaggtaat
    11161 tcacgcttta aacaccgttc tcgtggctat tttgaaagtc caatgaatga tattcctaac
    11221 tttaatattg gtaaacaagc taccttggat aaacatggtt atcgtgatcc gaaattggat
    11281 aaagtgcgat tctttaagaa acaggctctg cctcgatctt ctagtcaacc aagcgctgaa
    11341 ccaatggaaa atattgcctt aggaaaacag gttactcaaa gttcgacagc tttcggagga
    11401 gatgctagaa gagctgtgga tggcaaagtc gatggtaact atggtcacaa ttctgtcact
    11461 catacaaact tccaatctaa gccttggtgg caagtagatt tggctaaaga agaaaccatt
    11521 cgccaaatca atatttacaa ccgaacagac actgcccagg atagattggc aaactttgat
    11581 gtcattcttt tagacagttc tggtaaagaa attgagtgaa aacgtataat atctcctaaa
    11641 gatgtgtcag cacaaattac gattaaccat aaaaaagcgc gctatgttcg gattgagcta
    11701 gaaggctata atgccctcag tcttgcagaa gttgaagttt tccgctttat agctacgaat
    11761 gctgaaacgg cgacacaagt ttctaagcca gttcaaccaa tcagtcagac tcctgtgaaa
    11821 gataaaacat tgacaattca acacagtgga gcttacattg cccgctactc cataacttgg
    11881 gaagaagttc cagtagataa agatggaaac caagttgttc gtagtcattc ttgggaagga
    11941 aacggtcgca accagactgc gggttttgtc ctcaacctcc caatcaaaga aaatatgaga
    12001 aatctgcgag ttaagattga gaaaaagacg ggcctactat ggaatagatg gcaaacaatc
    12061 tatgaaaaca gaccaatttc agctcaaccc caccgtaaaa ttacccattg gggtacgaca
    12121 ttgaattcca aggtgagtga cgatgatgtc ttgtaatctg atggtacaat gacagttagt
    12181 ttgtctagtt tataagaaag tactacctga gcttgaatag aactcaggta gctctctgtg
    12241 aaagaacaaa attaatactc aatgaaaatc aaagagcaaa ctaggaaact agccgcaggt
    12301 tgctcaaagc actgctttga ggttgtagat aagactgacg aagtcagtca catatataat
    12361 ccaaggcgac gttgacgtgg tttgaagaga ttttcgaaga gtataaacag aaaggtagag
    12421 cgcgtgttct aatttgaaca cgagtagaaa acttttctaa aaacaaaaac gaaaggatgg
    12481 gtaaactgta ttcgctgaac tgaatacggg cgactctcct ctaaatcaaa attaagaaag
    12541 gaattgaccc caccctaaaa gtagtgggaa aaagatagtt ggtctagcga gcatcgctca
    12601 ctgcgcccaa ctcctatttt cccttcgctt tttgatgggt ttggtatctt tctcaatata
    12661 aaataaagaa aggtagagcg tgtgttttga tttgaacacg agcggaaaac tcggaaaata
    12721 gataatctga ctgaaaaatc aggatttctc gtcaggttcc taattttcag tcgttttctt
    12781 ctcgctcttt gtatcataaa ttatgtctat ccatattgct gctcagcagg gtgaaattgc
    12841 tgataaaatt cttcttcctg gggatcctct tcgtgctaag tttattgcgg agaatttcct
    12901 tgatgatgct gtttgtttta acgaagtgcg taacatgttt ggttacactg gtacttacaa
    12961 gggtcactgt gtatctgtca tgggaactgg gatgggaatg ccatctattt cgatttatgc
    13021 gcgtgagtta atcgtagact acggtgtgaa gaaattgatt cgtgtgggaa ctgcaggttc
    13081 tttgaatgaa gaggttcatg ttcgtgaatt agttttggcg caggcggctg caaccaactc
    13141 aaacatcgtt cgtaatgact ggccacagta cgattttcca caaattgcta gctttgattt
    13201 gcttgataaa gcctaccata tcgccaaaaa acttggtatg actactcacg ttgggaacgt
    13261 tttgtcatct gatgtctttt actcaaatta ctttgaaaag aatatcgagc ttggtaaatg
    13321 gggagtcaag gctgtggaaa tggaagcagc agctctttac tatcttgctg cccaatacca
    13381 tgttgatgcg ctagctatca tgaccatctc tgatagcttg gtcaatccag acgaagacac
    13441 aactgcagaa gaacgtcaaa ataccttcac tgatatgatg aaggttggtt tggaaacctt
    13501 gattgcagaa taattatagc caaaaaggaa gccctttatg aattgtagga cttccttttc
    13561 ttatccagaa attgatctag ctctctctga tttcgaagaa tagtgacttt atgtgaatat
    13621 tcttggcaaa gtttttggta attttctttt tgagttttgc tacgcccatc ccaaagaatc
    13681 catctgataa actcccactc aaagcgttca gggcaatctg ccgccatact ttctctgact
    13741 tttccacggt atttaagata acgcttaaag gctctaaaga gacaggtcaa tggcgaaaaa
    13801 ttgagaaaga tgatttggtc agcttcttgc attcgttctt ggtagtagca ccaagaataa
    13861 ttaccatcga tgacccaagc tttatgcttg gtgagaaagt tttttatctc ggttaacatc
    13921 cattcgcagt cactgtcttg ccaaccaggt tgaaattgga gtgtgtccat gtgcagtttt
    13981 ggaatggagt agtagttaga taacttttct gctatagttg acttaccaga accagaatat
    14041 ccgataattg cgattttcat tttctacttt ttcctatttg gagacaaaaa aacagcctct
    14101 atggactgtt tcttatttag caagtttagc tgaaagacga gctttatcgc ggcttgcttt
    14161 gtttttgtga atcaaacctt tagtttctgc tttatcgata gctgagctag cagcacggaa
    14221 aagttcttca gatgggtttg cttcgaaagc ttttatagca gtacgcatag ctgatttttg
    14281 agctgagttc ttttcgtttt gtttaacgtt caattcagcg cgtttgatag ctgatttaat
    14341 gtttgccaat gttcttacct ccatatttac taactatacc attatatatg aaaacttacg
    14401 ttttgacaag ggaaaattac ttttttaagt aaatttcatc gatttcatgg ttcttgcttt
    14461 tatgaagaat cacttctgca cgatttctgg ttggttcaat ataattttgc agatttgtga
    14521 gattgatact gatccagacc tgatgggcaa aggactccac ttccccaatc ggcatctgag
    14581 taaaacgata atagtagcta tcagggtcgt tttgggctag gctcagcatt ttcaagaaac
    14641 ggtccagata ccaactttca atatcatcca ctccagcatc tacatagatg gaaaagtcaa
    14701 agaagtcagt gatatagaga cgatcgtttt gtggattttg aaagacatta attccctcaa
    14761 caattacaaa atcagcagct ttgacacttt gtttcttttc gggtacgatg tcgtaaactt
    14821 catgagaata gacaggaata tctacatctt gtccattttt gatgcggtcc aagaagttga
    14881 gaagagcttc catatcatag ctttcaggaa atcctttacg atttaaaatc ccctgctcaa
    14941 tcaaggtttg attgggatag agaaaaccat cagttgtaac caactcaacc gtagcatctg
    15001 taaacgtacg ggacagtagg atttgaagta ggcgactggt tgtggatttt ccaacggcaa
    15061 cactcccaga aaccccaata ataaaaggtt gagatttact ttcacgttgg aggaaaattc
    15121 cttttgaaaa ggctaaatct tccttagttc gcttgtaaat ctgaatcaga tgagccaagg
    15181 ggagatagat atctgtaacg tcttggagac tgatttggtc attaaaactc ttgatagatt
    15241 ccaattcttc ttctgtcaaa ggaggtgttg tctttcgatg taaagattgc caagtctggc
    15301 ggctgatttt ttcaaaatgt aaaaattcgt tggtcatttg ttttccccta gatattttgt
    15361 ctatcatacc ataaaaagct aaaaaaataa agcggtttct tgaatgtggt aagtcaatgg
    15421 tatatagtat aagtgatcaa tttattgatg aaataggaga tagattctac tgatttataa
    15481 gcttataaag ggggcttttt agttcacaac ttataggagg tgtactatga aaatcttaaa
    15541 acgttacata ttggaactct gttttatttt aagttttgct ttacctttta taaaaggaac
    15601 caatgcagat aatggtagat gctttgtgga aacctattac ggttttactt ttttgatgga
    15661 acatgctatt gtaacagctg tctttatcta ttcgttttta attgctttct tactaaaaaa
    15721 acgatgggcg aaatggattg ctgctggtag ttattgcttt ttagtcctat ggattgcgac
    15781 agagggttat ttcttccgca tgtcactaga agatttgata cgactttgga caagtttgga
    15841 aatcctgaca caaacgtatc agttgggctt ttatctaaac attttgttag gaattttgtt
    15901 gataataaag tattttaagg ttaagcaata gaaataataa tctgcctgat tatagatgat
    15961 aaactttttg tttttatctg gactgtgata tttatagttc taaatggttt attatttata
    16021 agtgttgaaa gagattgaag aaaatggctt cgtgacttgc tttcttcggt ctttttcgtt
    16081 ttattatcaa tttgtaaacg atttacaatt tgagtcaaat tatggtaaaa tagtgtcatg
    16141 agtaaaatgt attatgcaga aaatcctgac gctgctcacg acattcatga gttgagagtg
    16201 gacttgttgg gacaaaaaat gacttttttg acagatgcgg gtgtttttag caagaaaatg
    16261 gttgactttg gaagtcaact cttgctcaag tgtctggatg tcaaccaagg agagacagtc
    16321 ctagatgtag gctgtggtta tggtccatta ggtttgtcct tggtcaaggt ttacggagtt
    16381 caggcgacca tggttgatat taacactcgt gccttggatt tagctcggag aaatgctgaa
    16441 aaaaataatg caaaagcgac gattttccag tccaacatct atgaacaagt tgaaggacat
    16501 tttgatcatg tcatttccaa tcctcctatc cgtgcgggca agcaagtcgt tcatgaaatc
    16561 attgagaaaa gtaaagattt cttggaaact ggtggggatt tgacaatcgt catccagaaa
    16621 aaacaagggg ctccaagtgc taagtccaag atggaggatg tgtttggtaa ttgtgaaatc
    16681 cttaaaaaag acaaaggata ctatatcctt agaagtgtga aagaatgaga gcagttgatt
    16741 taatacaaaa aaaacgagac ggtcaagaac tgacttcaag tgaaattgaa tggctggtag
    16801 aaggctatgt gtcaggaact gttcctgatt atcagatgtc tgcctttgct atggctgttt
    16861 attttaaagg aatgacgact cgtgaaattt ctgatttaac gatgaatatg gttaagactg
    16921 ggcaagagtt tgacctgtca gccattgatg gtgtgaaagt tgacaagcat tctactggtg
    16981 gtgtcggcga taaggtaacc ttgattttag ctcctcttgt tgctagcttc ggtgtgcctg
    17041 tagcaaaaat gagtggtcgt ggtcttggcc atacaggcgg aacaattgat aaattggagt
    17101 ccattagggg ctatcaagta gaacgtagtc aagaggattt tattcgtcag gttcaggata
    17161 ttggagtatc tgtcattggg caatcagacc agctggtcaa agcagataag cttctctatg
    17221 cccttcgtga tgtgaccgca actgtcgaca cgattccttt gattgcgagt tcggtgatga
    17281 gcaagaaaat tgcggcaggg gcggatgcta ttttgctaga cgtgactgtc ggtgagggtg
    17341 ccttcatgaa gacggttgat gaggcgcgtg agttggctca aactatggta gatcttggta
    17401 aggttgttgg acggaagaca gtagcagtga ttacggatat gagccagcct ttgggacgag
    17461 cgattggaaa tcgtctggaa atacttgaag cattggagat tttgcaaggt caaggacgtc
    17521 aggatattac ccactttatt tgtgaattgg ctcaaattat gcttggtttg gcaaatgtta
    17581 acaagactgt tgaagaagtt caccaacatc ttgagaatgg tcaagcactg gctaagtttg
    17641 aggaaatggt gcaagcccaa ggtggagact tggaagacct ctatcgtcct gtaaatgtag
    17701 ctcatgtggt ggaaatccct gctcaggaaa cgggtgtcat ttcagctctt ccagctatgg
    17761 actttggtct ttatgccatg aggctggggg ctggtcgtgc agttaagtct gatgccttgg
    17821 actatgaaac aggaattgtt tttgaaaaga agattggaga ctccgttcaa aagggtgaaa
    17881 ttgttgcaaa agtatacaca aatgaaaaaa ttccacctca actagttaca gatttccaaa
    17941 aatgtgttaa aataagtgat gaagtgaaaa aaatccgtga aattgtagaa atcatctcct
    18001 aaatggaggg aaaaccgaaa tgaaattaaa taaatatata gatcatacgc ttttaaaaca
    18061 agatgcaaag aaaaaacaaa ttgatagttt gttgtctgag gctagagagt atgactttgc
    18121 cagtgtttgc gttaatccga cctgggttga acatgctaaa aaaggacttg aaggcacaga
    18181 tgttaaggtt tgcacggtag taggtttccc tttgggagca acaacttcag ccgtgaaagc
    18241 atttgagaca aaagaagcta tccaaaatgg tgcagatgag attgatatgg tgatcaatgt
    18301 tggagctctc aaatcaggta atttagcctt ggttgagtca gatattcgcg cagtagtgga
    18361 agcaagtggt gataagttag tgaaagtcat tattgaagct tgccttctga cagaccaaga
    18421 aaaaattgtt gtttgccaat tggcccaaaa agctggggct gactttgtta aaacatctac
    18481 tggtttttca actggtggtg ctacgatagc agatgttaca ttaatgcgtg aaacagttgg
    18541 atctgatatg ggagtcaagg ctgctggtgg agctcgttct tatgcagatg ctcttgcctt
    18601 tgtcgaagca ggtgcgaccc gtatcggaac gtcagctggg gtagctattt taaaaggaga
    18661 attggcagat ggcgactact gagttgattg aactggcaat tgaaaccagc aaacatgcct
    18721 atgtccccta ttctcacttt cctatcggag cagttttagt agccaaagac ggaagtgttt
    18781 acacgggagt gaatatcgaa aatgctagct atcctttgac caattgcggt gagagaacag
    18841 ctatttttaa ggctatatct gaaggccaaa gagaattttc agaattgatt gtctatggtc
    18901 aaactgaaaa accgatctcg ccatgtggtg cttgtcgcca agtgatggct gaattttttg
    18961 aacaagatct aaaagtgacc ttagtcgcaa aagataaatc gacggtcgag atgacggtcg
    19021 gggaattact tccatactct tttacagact taaactagtc tgagtcgctc tctgagtggc
    19081 acggtccttg tggccaacca atccatactt gcaacatcgt tgcacatctt atttaggagg
    19141 ttcagtaatg aacaagaaac aatggctagg tcttggccta gttgcagtgg cagcagttgg
    19201 acttgctgca tgtggtaacc gctcttctcg taacgcagct tcatcttctg atgtgaagac
    19261 aaaagcagca atcgtcactg atactggtgg tgttgatgac aaatcattca accaatcagc
    19321 ttgggaaggt ttgcaggctt ggggtaaaga acacaatctt tcaaaagata acggtttcac
    19381 ttacttccaa tcaacaagtg aagctgacta cgctaacaac ttgcaacaag cggctggaag
    19441 ttacaaccta atcttcggtg ttggttttgc ccttaataat gcagttaaag atgcagcaaa
    19501 agaacacact gacttgaact atgtcttgat tgatgatgtg attaaagacc aaaagaatgt
    19561 tgcgagcgta actttcgctg ataatgagtc aggttacctt gcaggtgtgg ctgcagcaaa
    19621 aacaactaag acaaaacaag ttggttttgt aggtggtatc gaatctgaag ttatctctcg
    19681 ttttgaagca ggattcaagg ctggtgttgc gtcagtagac ccatctatca aagtccaagt
    19741 tgactacgct ggttcatttg gtgatgcggc taaaggtaaa acaattgcag ccgcacaata
    19801 cgcagccggt gcagatattg tttaccaagt agctggtggt acaggtgcag gtgtctttgc
    19861 agaggcaaaa tctctcaacg aaagccgtcc tgaaaatgaa aaagtttggg ttatcggtgt
    19921 tgatcgtgac caagaagcag aaggtaaata cacttctaaa gatggcaaag aatcaaactt
    19981 tgttcttgta tctactttga aacaagttgg tacaactgta aaagatattt ctaacaaggc
    20041 agaaaaagga gaattccctg gcggtcaagt gatcgtttac tcattgaagg ataaaggggt
    20101 tgacttggca gtaacaaacc tttcagaaga aggtaaaaaa gctgtcgaag atgcaaaagc
    20161 taaaatcctt gatggaagcg taaaagttcc tgaaaaataa tggatggaag tcatttctta
    20221 ggaagcggcc aagggccgct tttttaagag ttgagacaaa gtcattttgt ctcagtaaag
    20281 cttgctacta gacaaactag caagttttat tgaaataaaa taagactctg aaaggaagag
    20341 cacatggcac acgaaaatgt cattgagatg cgtgatatta ccaaggtgtt tggtggattt
    20401 gttgccaacg acaaaatcaa cttgcaccta cgaaaaggtg aaattcatgc acttttagga
    20461 gaaaatgggg ctggtaagtc cacgctaatg aacatgttag caggccttct tgaaccaact
    20521 agtggtgaaa tcgcggtcaa cggtcaagtt gtcaatctcg actccccatc taaagcagct
    20581 agcttgggaa tcgggatggt tcaccagcac tttatgttgg ttgaagcctt cacagtggct
    20641 gaaaacatca ttttaggtag tgaattgact aaaaatggtg tgctagatat cgctggagct
    20701 agcaaagaaa tcaaggctct ttctgaacgt tatggcttag ctgttgaccc ttctgccaag
    20761 gtagcagata tctcagttgg agcccaacaa cgtgtagaaa ttttaaaaac actttatcgg
    20821 ggggctgata tccttatctt tgacgaacca acggctgttt tgactccatc agaaattgat
    20881 gagttgatgg ctattatgaa aaatcttgtc aaagaaggaa aatcaattat cttgattacc
    20941 cacaaattgg atgaaattcg cgcagtttct gaccgtgtta cagttatccg tcgtgggaaa
    21001 tcaattgaaa ccgttgaaat tgcaggggct accaatgctg atttggcgga aatgatggta
    21061 ggacgttctg tttcctttaa aacagagaag caagcctcta aaccaaaaga agtggttttg
    21121 tctatcaaag atttggtggt caatgaaaac cgtggtgttc cagctgttaa aaatctgtcc
    21181 ttggatgttc gtgctggaga gattgttggt attgcgggga ttgatggaaa tggtcagtct
    21241 gaactgattc aagccattac aggtcttcgt aaggttgaat ctggtagcat tgagctaaaa
    21301 ggagattcaa ttgtaggctt gcacccacgt cagattacag aactaagtgt tgggcacgtt
    21361 ccagaagacc gtcaccgtga tggcttgatt ttggaaatga tgatatctga aaatattgcc
    21421 cttcaaacct actataaaga accacatagt aaaaatggaa ttttgaatta ttcaaatatt
    21481 acttcttatg ctaaaaagct gatggaagag tttgatgttc gcgctgccag tgaattagtt
    21541 cctgcagctg cactctcagg aggaaatcaa caaaaagcaa ttattgctcg tgaaattgat
    21601 cgagatcctg atctccttat cgttagccag ccaactcgtg ggttggatgt cggtgccatt
    21661 gagtatatcc acaaacgctt gattgaagag cgtgataatg gcaaggctgt ccttgttgtc
    21721 agctttgaat tggatgagat tttaaacgtc tcagaccgta ttgccgttat ccacgatggt
    21781 aagattcaag gtattgtatc accagaaaca accaataaac aagaacttgg tgtcttgatg
    21841 gctggtggaa acttgggaaa ggagaagagt gatgtctaaa aaattacaac aaatttcggt
    21901 tcccttgatt tctgtatttc taggaatttt actcggagcc attgtcatgt ggatcttcgg
    21961 ttatgatgct atttggggct acgaagaatt gttctataca gcctttggca gtctgcgtgg
    22021 gattggagaa atcttccgtg ctatgggtcc tctggtcttg attggtcttg gttttgcggt
    22081 tgccagtcga gctggtttct ttaacgtcgg acttcctggt caggctttgg caggttggat
    22141 tctcagtggt tggtttgcgc tgtcgcatcc agatatgccc cgtcccttga tgattctagc
    22201 aaccatcgtg attgccttga ttgctggtgg gattgtcgga gcgattccag gtattcttag
    22261 ggcctatcta gggacgtcag aggttattgt aaccatcatg atgaactaca ttgtcttgta
    22321 tgtagggaat gcctttatcc atgctttccc taaagacttc atgcaaagta cagattcgac
    22381 cattcgtgtt ggggctaatg caacctatca gacaccttgg ttggctgagt tgactggtaa
    22441 ctcacggatg aatattggta ttttctttgc catcattgcc gttgcagtta tttggttcat
    22501 gctcaagaaa acaactcttg gttttgaaat ccgtgcagtt ggtcttaatc cacatgcttc
    22561 agaatatgct ggtatttctg ccaagcggac tattatccta tctatgatta tttcaggtgc
    22621 cttggcaggt cttggtggag ctgttgaagg tttgggaacc ttccagaacg tctatgttca
    22681 aggttcgtca ttagctatcg gatttaacgg aatggcggtt agtttgcttg cggccaactc
    22741 accaattggt atactctttg cagccttcct atttggcgtt ctccaagttg gggctcctgg
    22801 tatgaatgcg gcgcaggtac catctgagct tgtcagcatt gtaacagcgt ctattatctt
    22861 ctttgtcagt gttcattacc ttatcgaacg ctttgtcaaa ccgaaaaaac aagttaaagg
    22921 aggtaagtaa agatgtctat tataaccttg ctccccctct tggtgtcttc tatgctgatt
    22981 tactcagcac ctctcatctt tacaagtatc ggtggtgttt tctctgaacg tggtggtgtg
    23041 gtaaacgttg gccttgaagg aattatggtt atgggtgcct tttctggagt tgtctttaac
    23101 cttgaatttg cagaacaatt tggagcagca actccatggc tatccttgct tgtagcagga
    23161 ttggttggta gtgttttctc tatcatccac gcagcagcga cggttcattt ccgtgcagac
    23221 catgttgtca gcggtacggt attgaacttg atggcgcctg ccttggctgt tttcttagtt
    23281 aaagttcttt ataacaaagg acaaaccgac aacctaagtc aaacttttgg acgctttgat
    23341 ttcccagtct tggcaaatat cccagtgatt ggtgatatct tcttcaagtc aactagtcta
    23401 cttggttatc tggcgattgc cttctcattc cttgcttggt ttattctctt taagactcaa
    23461 tttggtcttc gtctccgctc tgtcggtgaa catcctcaag cagcggatac cttgggaatc
    23521 aacgtctaca agatgagata tttagggatt attatttcag gttttctagg tggaattggc
    23581 ggagcgattt atgcgcaatc aatctcagtt aacttctcag tgacaactat tgttggacct
    23641 ggatttatcg cccttgctgc gatgatcttt gggaaatgga atccaatcgg tgctatgctt
    23701 tctagtctct tctttggact ttcacaaagt ttggctgtta tcggttctca attgccgttc
    23761 ctacaaggag tgccagcggt ttatcttcaa attgcacctt atgttttgac aattcttgtc
    23821 ttagcagcct tctttggaaa agcagtcgca ccaaaagcag atggtatcaa ctacatcaaa
    23881 tcaaaataag catacaaaaa aacgtcagtc caatgactga actgcccccc aaaagttaga
    23941 cagaaaaaat ctaacttttg gggtg
//
LOCUS       DAVBCA010000030        23312 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.030, whole genome shotgun sequence.
ACCESSION   DAVBCA010000030 DAVBCA010000000
VERSION     DAVBCA010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23312
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.030"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(196..654)
                     /locus_tag="VQU19_001159"
     CDS             complement(196..654)
                     /locus_tag="VQU19_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HET2480414.1"
                     /translation="MKKQVFHDAAAGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWAAIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(651..1091)
                     /locus_tag="VQU19_001160"
     CDS             complement(651..1091)
                     /locus_tag="VQU19_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2480415.1"
                     /translation="MKVELQISETYEEEKLIVQAPQPTDKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPTNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            1675..2541
                     /locus_tag="VQU19_001161"
     CDS             1675..2541
                     /locus_tag="VQU19_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2480416.1"
                     /translation="MGTLLATRLKNRRKELKMSQRELAEGICKQGQISRLESGEFTPG
                     ADFLHALAKKLKVSMDYFFDEQVVEKVEELSEFKKLAQTFITNRNYESLKYIYELENV
                     KAHRLSLADKIYMEWIKSLIDFYFYGQKEDAIVRLEGVLSQLSVSDLNYLQVSNTLFN
                     FYYDIGDLGRFNKIREKLEYQVNHLNLSTIEELELSIKFNYNVCRYLWLQKNIEEAIT
                     KITATIKQCKAYRTNYLLADLYLLMGNVSENFSSKSSVKEYFETAYFLYKLEENMSMT
                     LKVEHYIADITE"
     gene            2878..3435
                     /locus_tag="VQU19_001162"
     CDS             2878..3435
                     /locus_tag="VQU19_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase family
                     flavoprotein"
                     /protein_id="HET2480417.1"
                     /translation="MDKKNLLVLVTGSVGASNVDTYLYYIKKFYNVKVILSENSKKFI
                     SKELISYFCDKVYDEIFVEEVVPHVFLPYESDLLLILPATANVIGKIANGIADDLVTA
                     TVLNFNKKIIFCPNMNSTMWDNHIVQRNVSILKELGHIFLFESKKTYEVGLRKAIDST
                     CSMLQPQSLVKELIKLENIVLEEGH"
     gene            3656..4762
                     /locus_tag="VQU19_001163"
     CDS             3656..4762
                     /locus_tag="VQU19_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="HET2480418.1"
                     /translation="MINKKIQQVVLESLQNFLNGNFISPCVVYDFGLLETVLDEFKNQ
                     IPVTFNYQLFYAVKANSNEKILEFLVDKIDGVDVASLSELDVAKKFFPPTQISVNGPA
                     FSYETLYNLIKKQYKVDINFLEHLQQFSPKESVGIRVTEPDELNNRMSRFGINICSDN
                     WTSNLQNPLITRLHFHFGEKDDKFIVKLDKILFKLQEINKLREVREINLGGGFMKLFM
                     ENRLKEFFLSLMEIYKKYDIDSTVTTIIEPGSAITSFSAYMITSPVNVSEVNEQQVIT
                     LDTSIYTNTLWFVPHIITTLNSSSKERYSTILYGNTCYEHDKYKMKVSLPRLTQNSSI
                     VFFPVGAYIKSNHSNLHRNDFMREVYLWTKNLTY"
     gene            4738..6129
                     /locus_tag="VQU19_001164"
     CDS             4738..6129
                     /locus_tag="VQU19_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480419.1"
                     /translation="MDKKLDILDKVKEYLGNKTTQILDNQYKEFLKLNDIRRAFGISE
                     KVLNNSFNFTSKEFNDLINNENYLFEYACRIREEWRKKCFNHSYRFLCSPIITDDFLN
                     TKTLRSSQIEYKYERYLSKSSIGDRAVDGFVSFNTLTANGMSAIKLCLEILNSIFFKK
                     KIDLLYSTGYYETRFLLNNLAKSGISCYEVSNCELDKDKFYNVFMMEPNRADLTLQKT
                     DFKIVEYFVKYKNNSIKVVILDISYQGSNFKLVEFLEKFKFANVIIFVVRSLIKLDQM
                     GLELTNGGIIEVFIPNHLRKLKNFIEEEFNKFRNSHGANLSLYEYCLLDNSLTLKNDW
                     NYSDLVMKFTSNFYADIKDLFMENSDIEIIHEEGVPFVFLDLIGEGKKEYEMFFQWLN
                     FFYKQLGITLYARNSFGFRNLTVEYFGIIGTERYIFKICPGVYKGLSYYLMKFLLKSF
                     SNEYLKTTDEVNR"
     gene            6126..7304
                     /locus_tag="VQU19_001165"
     CDS             6126..7304
                     /locus_tag="VQU19_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET2480420.1"
                     /translation="MKNLIKLLIIRLIVNLADSVFYIVALWHVSNNYSSSMFLGIFIA
                     VNYLPDLLLIFFGPVIDRVNPQKILIISILVQLAVAVIFLLLLNQISFWVIMSLVFIS
                     VMASSISYVIEDVLIPQVVEYDKIVFANSLFSISYKVLDSIFNSFASFLQVAVGFILL
                     VKIDIGIFLLALFILLLLKFRTSNANIENFSFKYYKREVLQGTKFILNNKLLFKTSIS
                     LTLINFFYSFQTVVVPIFSIRYFDGPIFYGIFLTIAGLGGILGNMLAPIVIKYLKSNQ
                     IVGVFLFLNGSSWLVAIVIKDYTLSLILFFVCFMSKGVFNIIFNSLYQQIPPHQLLGR
                     VNTTIDSIISFGMPIGSLVAGTLIDLNIELVLIAISIPYFLFSYIFYTDNGLKEFSIY
                     "
     gene            7729..7962
                     /locus_tag="VQU19_001166"
     CDS             7729..7962
                     /locus_tag="VQU19_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000623387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET2480421.1"
                     /translation="MISIDLGGTNIKITVLSNDGEIETLWSITTDTSEKGSQIISDII
                     SSIKNKLTERNIPDSDLLGIGMGSCSSYFPCKS"
     gene            8245..10194
                     /gene="mutL"
                     /locus_tag="VQU19_001167"
     CDS             8245..10194
                     /gene="mutL"
                     /locus_tag="VQU19_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HET2480422.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKIQITDNGYGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(10519..10986)
                     /locus_tag="VQU19_001168"
     CDS             complement(10519..10986)
                     /locus_tag="VQU19_001168"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HET2480423.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(10987..12192)
                     /locus_tag="VQU19_001169"
     CDS             complement(10987..12192)
                     /locus_tag="VQU19_001169"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HET2480424.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(12212..12847)
                     /gene="ribE"
                     /locus_tag="VQU19_001170"
     CDS             complement(12212..12847)
                     /gene="ribE"
                     /locus_tag="VQU19_001170"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HET2480425.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLEQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(12832..13932)
                     /gene="ribD"
                     /locus_tag="VQU19_001171"
     CDS             complement(12832..13932)
                     /gene="ribD"
                     /locus_tag="VQU19_001171"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HET2480426.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(14067..14181)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            14338..14931
                     /gene="ruvA"
                     /locus_tag="VQU19_001172"
     CDS             14338..14931
                     /gene="ruvA"
                     /locus_tag="VQU19_001172"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HET2480427.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEA
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDGLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            14941..15504
                     /locus_tag="VQU19_001173"
     CDS             14941..15504
                     /locus_tag="VQU19_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HET2480428.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKIFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRDFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            15501..16178
                     /locus_tag="VQU19_001174"
     CDS             15501..16178
                     /locus_tag="VQU19_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2480429.1"
                     /translation="MMSNKNKGILIFAILYTVLFVFDGVKLLASLMPSAIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     VGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(16319..17350)
                     /locus_tag="VQU19_001175"
     CDS             complement(16319..17350)
                     /locus_tag="VQU19_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HET2480430.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLPHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGRALFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNAGHATPRAIVPFGVHAHVDAQE
                     QVIRFDYNK"
     gene            complement(17605..18288)
                     /locus_tag="VQU19_001176"
     CDS             complement(17605..18288)
                     /locus_tag="VQU19_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HET2480431.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILASVFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(18300..19244)
                     /locus_tag="VQU19_001177"
     CDS             complement(18300..19244)
                     /locus_tag="VQU19_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HET2480432.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            19376..22207
                     /gene="uvrA"
                     /locus_tag="VQU19_001178"
     CDS             19376..22207
                     /gene="uvrA"
                     /locus_tag="VQU19_001178"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HET2480433.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAIKASSVEQIVDKVLELPERQRLQILSPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDNSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPNASKTLHEGALAPWNPISSNYYPNMLEQAMTAFGVAMDKP
                     FEDLSEEDKNLILYGSDGKKFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCHGYRLNDQALSVRVGGEQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVIGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            22200..23261
                     /locus_tag="VQU19_001179"
     CDS             22200..23261
                     /locus_tag="VQU19_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HET2480434.1"
                     /translation="MNKRVQAFLAKMQEKELDGVIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMGLTRIGFEDEISVSYY
                     HRMQAAFAGLNLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
BASE COUNT         7035 a         4105 c         4754 g         7418 t
ORIGIN      
        1 agatctgaaa taactgttat gatatagagg attgaaacta gaatagtaca cctctgcttc
       61 taaaacattg ttagaaatcg atttgactgt cctgatcgat ttatcctgtt cttatttcat
      121 ttcactatag taaggtgcag caggataaag aaaaaccgag aagtttcttt ctcggatttg
      181 cttattatga ggttcctatt ttctatgctc caagagttga ttgatgtgat ctactttttt
      241 agcctctctt ttatagagaa tagcccagat gatgagatag acaatcgcaa actcgataat
      301 gagctggagg tagaaaatcc agtggaaagg gaaccaacca gcaagagttg ctagtgggac
      361 aaagccagcc agcataagga agaaatgagt cagagtggca cgaagcatgc tccagtcacg
      421 gctgaataag cgattgccaa agttgaagag cataccaatg gctgcccaga taagtgtgca
      481 gtagagcaag accaaggcac cgtgaacctg atgctgatcc atcacttggc cgatgagaga
      541 gtagggattt agtggtgcgt aggtatttgg tgcataaatg agtgaaaaga ggatagagag
      601 gatgaggccg ataagaacac cggcagctgc atcgtgaaat acttgttttt tcatagttct
      661 aatttctcct tgatggtttt tagataacgg cgtgaagagt aggtgaagct ttcgtttttc
      721 aagaaaattt ctaccagacc gtttggcgtg agcttgaggt gagagatgga atcgatattg
      781 atgatttctg attgggaaat ttggataaaa ttggttggca agagtttaag aacctgatag
      841 agtcgcaaat caatgctgta ggtctgactc gcggtttctg ctagaacctt ccgattctcg
      901 atatagaagc gctgaatctt gccaatctca actagataga cctgatcatc gattttccct
      961 ttgatttttt ctctttggtc cagattttct gcgaactcga tgactttctg aactttatct
     1021 gtcggctgag gtgcttggac aatcagcttt tcctcctcgt aagtctcact aatctgtaat
     1081 tctactttca taaatttctc tccttgtttt tcatacaaaa ttaatctcac ttcttgtaca
     1141 cctttattaa tactcttcaa aaatctcttc aaaccacgtc agcgtcgtct tgccgtagga
     1201 tagttgttga ctttgtcagt tttatctaca acctcaaaac agtgttttga gctgtctgcg
     1261 cctagctttc tagtttgctc tttgattttt attgagtata ccactatttt actccctctg
     1321 gcaaggtact ttgtctatgt ggagggattg ggctcctatg tggtggagct tttctgttct
     1381 ttctgaaata tggtataata gcactaatca atttctagga aaatagatac agaaaggggc
     1441 tgaaagaact aggggaacag ttgtaattag aaggtgatag gtatgaaaag tggcgttgaa
     1501 gctggataag tttataaaga gtttgaatga agaaatgaaa agtaaataag ttgatgatga
     1561 attgcaaaaa tagattttat atacaatttg tatctttcaa atcattgatt tgaattttag
     1621 atttaatcat gttacaatta aaaatgaaat caaatagaag aggaagatgc aaacgtgggc
     1681 acactattag caacaagatt aaaaaataga cgaaaagaat taaaaatgtc tcagcgagaa
     1741 ctagctgaag gtatctgtaa acaggggcaa atcagtcgat tagagagcgg agagtttact
     1801 cctggagcag atttcttgca tgcccttgct aagaagttaa aagtcagtat ggattatttt
     1861 tttgatgagc aggttgtaga gaaagttgag gagttatcag aatttaagaa attagcacag
     1921 acatttatta caaatcgcaa ttatgagtct ttgaaatata tatatgaatt ggagaatgta
     1981 aaagctcacc gcctatcttt agcagataaa atctacatgg aatggataaa atctctgata
     2041 gatttttatt tttacggaca gaaagaagat gcgattgtac gattagaggg ggtattatca
     2101 cagttaagtg tatctgattt gaactatctc caagtttcaa acaccctatt caatttttat
     2161 tatgatattg gagatttagg tcgtttcaat aaaattcgtg aaaaactaga gtatcaagta
     2221 aatcacctca atttgagtac aatcgaagag ttagaactat ctattaagtt taactacaac
     2281 gtttgtcgtt atctatggtt acagaaaaat attgaagaag ctattactaa aattacagct
     2341 actataaaac aatgtaaggc ttacagaacg aattatcttt tggctgattt gtacttattg
     2401 atgggaaatg taagtgaaaa tttttcttct aaaagttcgg tgaaagaata ttttgagacg
     2461 gcatattttc tatacaaact tgaggagaac atgtcaatga ctctgaaagt tgagcattac
     2521 attgcagata taacagaata atgaatacgg tgttcaagtg agcatcgttt ttcaaaccta
     2581 gttcagatac aaaaaagtat caaataaaaa aaaataaaaa aacattataa aaacaattga
     2641 caagctaatt ttgaagtgat aaaataaatg caagaaaaca aaaggagagg tatatgagaa
     2701 gtttgtttaa gaaaatagtt gctgtattag ttattggctt aattctgtta ggaattgcga
     2761 gaacacctca agttcataag atggctagag ggattgatcc tggtcctgcg aattttattt
     2821 agaaatcaat ttctactaat tgagtactaa ttgagtatta atgggtaaaa agattgtatg
     2881 gataagaaaa atttacttgt attggttact ggttcggtag gtgccagtaa tgtagataca
     2941 tacttatatt atataaaaaa attctataat gttaaagtga tactttctga aaattctaaa
     3001 aaatttataa gtaaggaatt aattagttat ttttgtgata aagtttatga tgaaatattt
     3061 gttgaagagg tagttccgca cgtttttctg ccatatgaat ctgacttact tcttatttta
     3121 ccagctacgg caaatgtgat tggcaaaatt gctaatggta ttgctgatga tttagttaca
     3181 gcaactgttt taaactttaa taaaaaaata attttttgtc ccaatatgaa ctctactatg
     3241 tgggacaatc acatagttca aagaaatgta tcaattctaa aggagttggg acatatattt
     3301 ttatttgagt ctaaaaaaac atatgaggta ggattgcgta aagcaataga ttcaacatgt
     3361 tcaatgttac aaccacagtc gttagtaaaa gaacttatca aattagaaaa tattgtcctt
     3421 gaagagggac attaaaaact actgagaata ttaaggaggg gaaaaaatgg aaaattcatc
     3481 aatcgatgta gatatgctgt tggaagaatt gacacaagaa gcaatggtcg ttgttgctgt
     3541 tgataaggac tgttaattta aacttatggc aatatatgaa aggttactgg atgttttaaa
     3601 ttatgcaggc agtagccttt tattatatac aaatggataa agtaaggata atacaatgat
     3661 taataaaaaa atacaacaag ttgttttgga atcattacag aattttttga atgggaactt
     3721 catttcgcct tgtgtagtct atgattttgg cttgctggaa actgtacttg atgaatttaa
     3781 aaatcaaatt cctgtaacat tcaattacca acttttttat gccgttaaag caaattcaaa
     3841 tgagaagata cttgaattct tagtagataa aattgatgga gttgatgtgg cgtcattatc
     3901 tgaattagat gtggctaaaa aatttttccc accaactcaa atttctgtta atggtcccgc
     3961 attttcttat gaaactttat ataatctgat taaaaaacaa tataaagttg atattaactt
     4021 tttggaacat cttcaacaat tttccccaaa agaatctgtt ggaataagag taacggagcc
     4081 agatgaactt aataatcgta tgagtcgatt tggaataaat atttgcagtg ataattggac
     4141 tagtaattta caaaatcctt taattacacg actgcatttt cattttggag aaaaagatga
     4201 taaatttatt gttaagttag ataaaatatt atttaagtta caagaaatta ataaacttag
     4261 agaggttaga gaaataaatc ttggaggcgg ttttatgaaa ttatttatgg aaaatcgttt
     4321 gaaagaattt tttctatcac ttatggaaat ctataaaaag tacgatattg atagtactgt
     4381 gactacaata atagaaccag gtagtgcaat tacttcattt tctgcctata tgattactag
     4441 cccagttaat gttagtgagg tgaatgagca gcaggttatc acgttagaca catcaatata
     4501 caccaataca ttatggtttg ttccgcatat tattacaacg ttaaattcaa gtagtaaaga
     4561 gcgttatagt actattctct atggtaatac ctgttatgaa catgacaagt ataaaatgaa
     4621 agtttcgctt ccaaggttaa ctcaaaatag cagtatagtg ttttttcctg taggagctta
     4681 tataaaaagc aatcattcaa atttacatcg taatgatttt atgcgggagg tatatttgtg
     4741 gacaaaaaac ttgacatatt agataaagtt aaggaatatt taggaaataa aactactcaa
     4801 attctggata atcaatataa agaatttttg aaacttaatg atataaggcg agcgtttggt
     4861 atttcagaaa aagtattaaa caattctttt aattttacga gtaaagaatt taatgattta
     4921 attaataacg aaaattattt attcgaatat gcatgtagaa ttagagagga atggagaaaa
     4981 aaatgcttta atcattctta tcgttttcta tgctcaccta taattacaga tgattttctt
     5041 aacacgaaga cattgagaag tagccaaatt gaatataaat atgagcgata tttatcgaaa
     5101 agttcgatag gcgatagagc ggttgatggc tttgtttcct tcaatacttt aacagctaat
     5161 ggtatgtctg ctattaaact atgtcttgag atattaaact ctattttctt caagaagaag
     5221 attgatttat tatattcaac cggatattat gaaacaagat ttttattaaa taatcttgct
     5281 aaatcaggta ttagttgcta tgaggtaagt aattgtgaat tggataaaga taaattttat
     5341 aatgtattca tgatggaacc caatcgagcc gatttaacat tacaaaaaac tgatttcaag
     5401 atagtagaat attttgttaa gtataaaaat aattcaataa aagtcgttat tttagatatt
     5461 tcatatcaag gttctaattt taaattagta gaatttttag agaaatttaa atttgcgaat
     5521 gtaattattt ttgtggtacg atctttgata aaattagatc aaatgggatt agaattgaca
     5581 aatgggggaa taatagaagt gtttattcct aatcatttga gaaagttgaa aaattttatt
     5641 gaagaggaat tcaataaatt tagaaattct cacggagcta atctaagcct ctatgaatac
     5701 tgtttgcttg ataattcttt aaccttaaaa aatgattgga actattctga tttagttatg
     5761 aaatttacga gtaattttta tgctgatata aaagacttgt tcatggaaaa ttctgatatt
     5821 gaaatcatcc atgaagaggg agtacctttt gtatttttag atttaatagg tgaaggtaaa
     5881 aaagaatatg aaatgttttt tcaatggtta aacttctttt acaaacagct tggaatcaca
     5941 ttgtatgcta gaaatagttt tgggtttcgg aatctaacag tagagtattt tggaattatt
     6001 gggacagaaa gatatatatt taagatttgt ccaggtgttt ataaagggtt aagttattat
     6061 ttgatgaaat ttttattaaa atctttttca aatgaatatt taaaaactac tgatgaggtt
     6121 aatagatgaa aaatttgata aagttgctaa taattagatt gattgttaac ttagcagaca
     6181 gtgtatttta tatagtagca ttgtggcacg ttagcaataa ttattcttcg agcatgttct
     6241 taggaatatt tattgcagta aattatctac cggatttgtt actaatcttt tttggaccag
     6301 ttattgacag agtaaatccg caaaaaattc ttataatatc aattttggtt caattagcag
     6361 tggctgtaat atttttatta ttattaaacc aaatatcatt ttgggtgata atgagtctag
     6421 tgtttatttc agtaatggct agctccataa gttacgtgat agaagatgtg ttgattcctc
     6481 aagtggtaga atatgataag attgtatttg caaattctct ttttagtatt tcgtataaag
     6541 tattagattc tatttttaat tcattcgcat catttttaca ggtggcagta ggatttattt
     6601 tattggttaa gatagatata ggcatatttt tacttgctct atttatattg ttgttgttaa
     6661 aatttagaac tagcaatgcg aatatagaaa acttctcttt caaatattac aagagagaag
     6721 tgttgcaagg tacaaagttt attttaaata ataaattatt atttaaaacc agtatttctt
     6781 taacgcttat aaactttttt tattcatttc agacagtagt tgtaccgatt ttttctattc
     6841 gatattttga tggtccgatt ttttatggta tttttttaac tattgctggt ttgggtggta
     6901 tattgggaaa tatgctagcg ccaatcgtaa taaaatattt aaaatcgaat caaattgttg
     6961 gtgtatttct ttttttgaac ggctcaagtt ggttagtagc aattgttata aaagactata
     7021 ctttatcact tattttattt ttcgtttgtt ttatgtctaa aggagtcttc aatattattt
     7081 ttaattcgtt gtaccaacaa atacctccac atcaacttct tggtagggta aatactacca
     7141 ttgattctat tatttctttt ggaatgccaa ttggtagttt agttgcagga acgcttattg
     7201 atttgaatat tgaattagtg ttaattgcta ttagcatacc ttattttttg ttttcttata
     7261 ttttttatac ggataatgga ttgaaagaat ttagtatata ttagaaatgt ttatgttcat
     7321 tcaaaagcat aatgactata actgaaaaag aaaagtgata tctttaaggt tgttcttctt
     7381 ggtggtgaga ttcgtgagac aacccaagct tttgtcggaa agattaccaa tgctttgatg
     7441 gataggatgt actttagcaa gatgttttta gtggtaacgg tatcgtggat ggacgtgtaa
     7501 taacctcttc tttcgaggag tattttacta aaaaactagc cttggagcgt tccccagaaa
     7561 cggacttact cattgactct tcaaagattt ggggagaaga ttttgcttca tctgttcctt
     7621 gaaaaaagtc acagcagtca tcacagacga tagtactgaa caaaactatg aagagttaga
     7681 aatttatacg caggtgattg tataaaggat ctggaaatag ataagaagtt gattagtatt
     7741 gacctaggtg gtacaaatat taagattact gttctttcaa atgacggtga gattgaaact
     7801 ttgtggagta ttacaacaga tacaagtgag aaaggttctc aaattatatc ggacatcatc
     7861 agttctatta aaaataaatt gaccgaacgg aatattcctg atagcgacct tcttggaatc
     7921 ggtatgggaa gttgctcatc atactttcct tgtaaatcat aggggctata aactctccgt
     7981 ctacttgtcc tgcaacaatt gaagtctgct caaaacgccg tccgctaatc ttttcataga
     8041 ctttctccct tttaggagcc tagctttcta gtttgttctt tgatttttat tgagtatacc
     8101 actattttac tccctctggc aagggacttt gtctatgtgg agggattggg ctcctatgtg
     8161 gtggagcttt tctgttcttt ctgaaatatg gtataatagc actaatcaat ttctaggaaa
     8221 atagatacgg aaaggggctg aaagatgtct catattattg aattgccaga gatgctggca
     8281 aaccaaatcg cagctggaga ggtcattgaa cgtcctgcca gcgtggtcaa agaattggta
     8341 gaaaatgcca ttgacgcggg ctctagtcag attatcattg agattgagga agctggtctc
     8401 aagaaaatcc aaatcacaga taacggttat ggaattgccc acgatgaggt ggagttggcc
     8461 ctgcgtcgcc atgcgaccag taagataaaa aatcaagcag atctctttcg gattcggacg
     8521 cttggttttc gtggtgaagc cttgccttct attgcgtctg ttagtgtctt gactctgtta
     8581 acggcggtgg atggtgctag tcatggaacc aagttagtcg cgcgtggggg tgaagttgag
     8641 gaagtcatcc cagcgactag tcctgtggga accaaggttt gtgtggagga tctctttttc
     8701 aacacgcctg cccgtctcaa gtatatgaag agccagcaag cggagttgtc tcatatcatt
     8761 gatattgtca accgtctggg cttggcccat cctgagattt cttttagctt gattagtgat
     8821 ggcaaggaaa tgacgcggac agcagggact ggtcaattgc gccaagcaat cgcagggatt
     8881 tacggtttgg tcagtgccaa gaagatgatt gaaattgaga actctgacct agatttcgaa
     8941 atttcaggtt ttgtgtcctt gcctgagttg actcgggcta accgcaatta tatcagcctc
     9001 ttcatcaatg gtcgttatat caagaacttc ctgctcaatc gtgctatttt ggatggtttc
     9061 ggaagcaagc ttatggttgg acgttttcca ctggctgtca ttcacatcca tatcgaccct
     9121 tatctagcgg atgtcaatgt gcatccaact aagcaagagg tgcggatttc caaggaaaaa
     9181 gaactgatga ccctggtttc agaagctatt gcaaatagtc tcaaggaaca aaccttgatt
     9241 ccagatgcct tggaaaatct tgccaaatcg actgtgcgca atcgtgagaa ggtggagcaa
     9301 actattctcc cactcaaaga aaatacgctc tactatgaga aaactgagcc gtcaagacct
     9361 agtcaaactg aagtagctga ttatcaggta gaattgactg atgaagggca ggatttgacc
     9421 ctgtttgcca aggaaacctt ggaccgattg accaagccag caaaactgca ttttgcagag
     9481 agaaagcctg ctaactacga ccagctagac catccagagt tagatcttgc tagcatcgat
     9541 aaggcttatg acaaactgga gcgagaagaa gcatccagct tcccagagtt ggagtttttc
     9601 ggacaaatgc acgggactta tctctttgcc caagggcgag atggacttta catcatagat
     9661 cagcacgctg ctcaggaacg ggtcaagtac gaggagtacc gtgaaagcat tggcaatgtt
     9721 gaccagagcc agcagcaact cctagtgccc tatatctttg aatttcctgc ggatgatgcc
     9781 ctgcgtctca aggaaagaat gcctctctta gaggaagtgg gcgtctttct agcagagtac
     9841 ggagaaaatc aatttattct acgtgaacat cctatttgga tggcagaaga agagattgaa
     9901 tcaggcatct atgagatgtg cgacatgctc cttttgacca aggaagtttc tatcaagaaa
     9961 taccgagcag agctggctat catgatgtct tgcaagcgat ctatcaaggc caatcatcgt
    10021 attgatgatc attcagctag acaactcctc tatcagcttt ctcaatgtga caatccctat
    10081 aactgtcctc acggacgtcc tgttttggtg cattttacca agtcggatat ggaaaagatg
    10141 ttccgacgta ttcaggaaaa tcacaccagt ctccgtgagt tggggaaata ttaaaagtat
    10201 aaaaaagtct gggaaaaatt ttcaaaatca gaaaaacgca taaaatcagg tgttcaaaaa
    10261 ccttgatttt atgcgtttta tcatggaaat agttacttca tgttttccta attcttttcg
    10321 aaactctttt taaaccacgt cagttttatc agtaatctca aaacagtgtt ttgagctaat
    10381 tttgccagtt ttatctgtaa catcgaagtt gtgtttgacc actctgcgac tggtttccta
    10441 gtttgctcta tgattttcac agagtattaa attgcgattt tgccaagttt ctttattcgt
    10501 ctaaaagtag agtctgttct atgcgtctaa tgtacgaatt aggttgacca tttcaatagc
    10561 tccttgtgca cactcagaac ccttatttcc tgctttggta ccagctcgtt ctatggcttg
    10621 ttcaattgta tctgtcgtta gcacaccaaa cataacagga atttcgctat ttaaactgat
    10681 ttgggcgatt cccttagata cctcgctaca tacataatca taatgacttg tattccctct
    10741 aatgacagct cccaagcaga taattgcatc atatttttta ctttttgcca tttttgatgc
    10801 aatcagtggt atttcaaaag ctcctggaac ccaggctacc tctatatctt tctcgtttac
    10861 attctctctt ttgagattat ctagtgctcc agataataat tttgaagtta taaattcatt
    10921 aaatctcgct acaacaatac ctattttaat attgtttgct actaaattac cttcataagt
    10981 gttcatttat ttttcctcca tatttaaaat gtgacccatt cgatttttct ttgtttctaa
    11041 ataaaaacta tcgtaaggat tggcttctat ttcgattgat attctactgg aaatggtaat
    11101 tccatatttt tctaactgtt caaccttgtc aggattattt gtcagtaaat gaagtgactg
    11161 aagtcccaga tctttaagca tttgtgctcc aatatgatat tctcttaaat caccttcaaa
    11221 gcctaatgca agattggcat caagcgtatc catgccttga tcttgtaaat gataggcttt
    11281 taatttattg ataagtccaa ttcctcgtcc ctcctgtcgc aagtaaagta agacacccga
    11341 accattctca acaatcattt tcatagcttt atcgaattgc tgtccacaat cgcaacgtaa
    11401 agagcctaaa acatctcctg ttaaacattc ggagtggacc cgacataata cattggcttc
    11461 atcctctata tttcccataa taagagcaag atgatgttcc ccatttagtt tatctatata
    11521 gctaattgct ttgaaattac cgtatctagt aggcatattg acagttgaaa ctcgttctac
    11581 cagctgatca tatacttttc tatattcttg taattctttg atggtaatta gtggaatgtt
    11641 gtgtttcttc gagaactgaa ttaaatcatc tgttctcatc attttgccat catgattcat
    11701 tatttcacaa cataggccac actcttttag tccagctaat tttaataaat caacagttgc
    11761 ttctgtgtgt ccatttcttt ctagaacacc accttttttt gcaattaaag gaaacatgtg
    11821 tcctggcctg cgaaaatcag agggtgttat atcttcagct acacacatac gtgcggtcag
    11881 tcctctctcc tcggcagaaa tacctgtggt cgtttcttta taatcaattg aaactgtaaa
    11941 agcagtctta tgattatctg tattgttttc aaccataggt gaaagcatta attgattagc
    12001 taaactttcg ctcataggca tacaaattaa tcctttggca taagtagcca taaaattaac
    12061 attttctgtt gtagctgctt gtgcagaaca aattaagtct ccttcatttt ctctatcctt
    12121 gtcgtctata acaagaacaa gtcgtccctt ctgcaatgct tctaatgctt cttgtatttt
    12181 tcgatattcc attgactgat tatcctttct gctaaaatcc attttgatat aatagttcct
    12241 tagatatttc tgattttgga gagttatcca tcagtttttg cacatattta cctaagatat
    12301 cattttcaag atttactgta ctcccgactt gtttactctt aagaatggtt tgttccaagg
    12361 tatgagggat aacagatact gaaaagttta ctttggagac tttagcgaca gtcagactaa
    12421 tgccgtcaat tgtaatagat cctttttcaa ctattaaatc taaaatttct ttttgtgtgt
    12481 tgatttgata ccatacagca ttatcatctt tttttattga cgagattttt cctgtaccat
    12541 caatgtgtcc tgtaacgacg tgacccccaa gtcgaccgtt gacagataag gctctttcta
    12601 gattcacctc acttccatgt tttaatagag taagagctgt tcgactccat gtttcattca
    12661 ttacatcaac tgtaaaggat tgatgattga aatgagtaac tgtaagacag ataccattta
    12721 ctgctatact atcgcctaaa tggatatccg ttaatatttt tgaggcttta attgatagtt
    12781 tacaattacg agagtctttc tgtattcttt caacttttcc gatttcttca attattcctg
    12841 tgaacatgga taaatcactt cactttctat gagatagtca tttcctattt gagaaaaagc
    12901 ataaggtttc aatctaatag cgtcatttgg caaagaaatg ccttcacctc cgacaggaaa
    12961 cttggcactg cctccaaaaa tttttggtgc aatatatatt ttcagctcat caacaatttg
    13021 ttgttccaaa gcactccaat tcattagact gcccccttct agaactaggc tatcaatctg
    13081 catgtttcct agatgttgca ttaaactcga taagtctata tgattgcctt ttttctttat
    13141 ggaaagtatt tcacagccat gattttgata tagcttcatt ttatttttgt cttcagagga
    13201 agtggcaatg taagttttaa tatcatttgc tgtttttacg attttagagg taagaggagt
    13261 tcgtaaatgt gtatcgcata tgatacggat aggatttttc ccttcctcca atctacatgt
    13321 cagcaaagga tcgtcttgaa taacagtatt gactcccacc ataattgcac taacatggtg
    13381 tcgtaactga tgcacatgct ttcttgcttc ttcttcagta atccatttgg attgatttgt
    13441 tttagtggct atttttccat ccattgacat tgcatatttc ataaaaacat agggtacatg
    13501 ctgggtaata tactttctaa aactttttat taagttaaga cactcatttt ctaaaattcc
    13561 aacagtaact tgaagattat tttcctcaag tatctttact ccttttccag atacaatagg
    13621 attacagtct aggcttccaa tgactactct tgtaatacca ctatcgatta tagcatctat
    13681 acagggaggt gttttcccga agtgacaaca gggttcaagt gttacataaa gcgtcgctcc
    13741 gacaggggat tctctacagt ttttaagagc atttctctca gcatgtgggc caccaaaaaa
    13801 ctcatgataa ccttgtccga tgatgtgatt atcttttaca ataactgcgc cgaccatagg
    13861 attgggattg acgtaaccag cccctttttg tgccagtttt attgctaatt tcatatattt
    13921 tgaatcgctc atctcactac ctccaaaaaa aatatacctt gaatagggga ctactcaagg
    13981 catacaaaag aaaacttatg cgattaacaa aaatactctg aaatgacaag taatcatttc
    14041 agagcacgca aaaagcacaa atatactttt atcttctttc atccagacta tactgtcggc
    14101 tttggaattt caccaaatca tgcctttcgg ctcgtgggct ataccaccgg tagggaatta
    14161 caccctgccc tgaagatagt tattcaatta cagatgatta tagtacttaa ttttgaatat
    14221 gtcaacagat aaataccgat tgtttttgat atactgtatt tgtgataatc gattctcgct
    14281 cctcggataa agaaaatatg atatactaga taaacgaaat aagagagaag gaatactatg
    14341 tacgcatatt taaaaggaat cattaccaaa attactgcca aatacattgt tcttgaaacc
    14401 aatggtattg gttatatcct gcatgtggcc aatccttatg cctattcagg tcaggttaat
    14461 caggaggctc agatttatgt gcatcaggtt gtgcgtgagg acgcccattt gctttatgga
    14521 tttcgctcag aggatgagaa aaagctcttt cttagtctga tttcggtctc tgggattggt
    14581 cctgtatcag ctcttgctat tatcgctgct gatgacaatg ctggcttggt tcaagccatt
    14641 gaaaccaaga acatcaccta cttgaccaag ttccctaaaa ttggcaagaa aacagcccag
    14701 cagatggtgc tggacttgga aggcaaggta gtagttgcag gagatggcct tcctgccaag
    14761 gtcgcagtgc aagcaagtgc tgaaaaccaa gaattggaag aagctatgga agccatgttg
    14821 gctctgggct acaaggcaac agagctcaag aaaatcaaga aattctttga aggaacgaca
    14881 gatacagctg agaactatat caagtcggcc cttaaaatgt tggtcaaata ggagcagaga
    14941 atgacaaaac gttgttcgtg ggtcaagatg accaacccac tctacatcgc ctatcatgat
    15001 gaggagtggg gccagcccct ccatgatgac caagcgttgt ttgagttatt gtgtatggaa
    15061 acctatcagg caggcctgtc ttgggaaacg gtactcaaca aacgccaagc tttccgagaa
    15121 gcctttcata gctatcaaat tcactcagtc gcagagatga ctgacactga attggaagcc
    15181 atgctggaga atccagctat cattcgaaat agagccaaga tttttgctac acgcgctaac
    15241 gcccaagctt ttctacagtt acaggcagag tacggctctt ttgatgccta tctttggtct
    15301 tttgttgagg ggaaaactgt cgttaacgat gttcctgatt atcgccaagc cccagctaaa
    15361 acacccttat ctgagaaatt agccaaagat ctcaaaaaac gagacttcaa gttcacaggc
    15421 ccagtcgccg tattgtcttt tctacaggct gcagggctag ttgatgacca cgagaatgat
    15481 tgtgagtgga aaggtcttaa atgatgtcta acaaaaataa gggaattctg atttttgcga
    15541 ttctctatac agtcctcttt gtgtttgatg gcgttaaatt gctggcttct ttaatgccat
    15601 ctgccattgc aaattatctt gtttatgtag ttttagctct atatggctcc ttcttattca
    15661 aggatagatt gatccaacaa tggaaggaga ttagaaagac taaaagaaaa ttcttctttg
    15721 gcgtcttaac aggatggctc tttctcattc tgatgactgt tgtctttgaa tttgtatcag
    15781 agatgttgaa gcagtttgtg gggctagtcg gacaaggtct aaatcagtct aatattcaaa
    15841 gcacttttca agagcaacca ctactgatag ctgtttttgc ttgtgtcatt ggacctctgg
    15901 tagaagaatt atttttccgt caggtcttat tgcattactt gcaggaacgg ttgccaggtt
    15961 tactaagcat tattctggta ggacttgttt ttgctctgac tcatatgcac agtttggctc
    16021 tatcagagtg gattggtgca gttggttact taggtggagg ccttgccttt tctattattt
    16081 atgtgaaaga aaaagagaat atctactatc cactacttgt tcacatgtta agcaacagcc
    16141 tctccttaat cattttagct atcagtatag taaaatgaaa taagaacagg acagtcaaat
    16201 cgatttctaa caatgtttta gaagtagatg tgtactattc tagtttcaat ttgctgtaat
    16261 atgtgatgaa aatgccagta atgataccga gaaaaaagct gagaaacttt tcccagcttt
    16321 atttgttata gtcaaagcga atgacttgtt cctgtgcatc tacatgagca tggaccccaa
    16381 agggtacaat tgctcttgga gttgcgtggc cggcattcag attatagaca atcgggatat
    16441 tgctgtcaat gatatccaat agtgcctctt tatagtcgtc atggaaagtt tcatccatag
    16501 gttttccgac caagagtcca ttgatgaccg cgaatatgcc agtgtccttt aaagttagca
    16561 acatcttttt gaagtcttct ggcttaggct tttcttcgct tgtttcgagc aagaggattt
    16621 tcccttccca gtctgacaag tcagggaaaa gtttgtattt ttggcagagc tccgtgctat
    16681 ctgcgtatcg agagttgtca aagatatcgt agagggattc gaggcaacca ccgaggattt
    16741 tcccctcgaa tagtgccctt ccttgcaaca agtcaaaacc tgtatttgta tgactgacac
    16801 gaggtgttcc cagggccgtg ggactaaaat cagttcgttc ctcataccaa acgtcactag
    16861 ggcggatttc tgaaattctt cccgtctcaa tcaattcttt aaagtagtga aggctatagg
    16921 ctagcatttc tttgtctaat tcacaaatgt ctgctaaaaa ggattgacca taaaaagtct
    16981 tgattcctaa tttatgcaac atgaggtggt tcatggttgt atccgagaag ccaagaaaaa
    17041 ttttttgctt gataaccttt tggagttggt cattttcaaa aagataaggt agcaagcgat
    17101 aggtatcgtc tccaccgatg gcacatagga tcatgtcgat gctatcatca gaaaaggcat
    17161 gaatcaaatc ctctgcacga gcttcaggat ggtccttgat aaagtctaat ccttttaacg
    17221 aatggggcaa aaagatggga ttgagtccca gatccttgag acgttggata cccaagtcca
    17281 cttcgtgttt gacaaaatcc tctccgataa tgccactaga taaactaaca ataccaatag
    17341 tagaaaccat atctcatcct cctagaaata gattgagcct attttatcac aaaatataag
    17401 agaaagctat gtgggatttc agaagaatac ttttaatact cttcgaaaat ctcttcaaac
    17461 cacgtcagtt ttatctgcaa cctcaaagct gtgctttgag caacctgcag ctagcttcct
    17521 agtttgctct ttgattttca ttgagtataa ctcaaaaaag taagtgaaaa agcaaccgca
    17581 cctgcagttg cttttatcgt tttcttattc ttgatagcgt gttggtcctg cacttgcact
    17641 acggatattc aagcgtttct tgagatagaa gcgaagggct aggagggctg ctccaataat
    17701 agctagtggc aatggatcca gtactgggtt aaggctagct ggtaggaagc ttgttgcaaa
    17761 gaagacaagc aaccaaagga acacagaagc taggataact agtacagatt tccagaaagg
    17821 tggacgttga ctgcgatcca tatctggtcc atagtattgg taaacaaagt agtacatcaa
    17881 gtagaaggca aatccaccaa ccagtccaac taatagaaga gtaatcaatc catagccgaa
    17941 agcttgatct gccgcaaaga aggttgtgag ggcgctgaca agggcaaaga ggctagtgat
    18001 gaaaagagct gagtccataa tcatcagttt tgggtcatca ttttcttttg gatgctcttt
    18061 ttcgtactgc tctttgacag tgaagctatg agcccaatga gttggtgcgc cgtataggga
    18121 acgggcagtt gtacctttag attgctcctc aaggatttgg ggaatgactt cctcaaaaat
    18181 agtctggatt tcagcgtctg ttttcccatc tttgatgaat tgttgggtag caatgtggac
    18241 aaactcttgg tttttcttag ttaatttttg tagatcaatt tgagacatag gaactccttt
    18301 tagaaccatt ttttatggat gagatagaga gtgagcgaga cactcatagc aaaggcgata
    18361 aagacgatta accagaaggc atttggctct ccgtttaggg gaatttcatt atccttaaag
    18421 ttcatcccgt aggcagaaaa gaccatggtt gggatggaca tgacgatggt cacaagggcc
    18481 aaggttttca tgatgttgtt ctggttgtta gaaatgatag aggcaaaggt ctctgtcata
    18541 gaatgcaaga cgtttccata aatatctgcc atctcgatgg cctgttgggt ttcaatcagg
    18601 gtgtcttcaa gcaggtcttc gtcctcaagg tatttcttga tattgctggt tgaactggtc
    18661 aatttcttaa tcacgcgctc atttgttttg agggaggcct tgaaatagac gatagttttt
    18721 tccaattcca tgagctcaat caattcttca ttacgagttg attgatgcag ttgactttcg
    18781 atttgttcac tcttgcggtc gattgaacga agggctgtta ggtaaagctc tgcattgcga
    18841 taaagaattt gaaagataaa acgtgaacgc atgaaggtat agaaattacg caatcgacgg
    18901 ttgataaaga catcaaggac aggtagtggt tccaaacacg tagtgataat ggtttcctca
    18961 gtgatgataa taccaagcgg gatggttacg tagtaggtgc ggttatttct ttcctccgtg
    19021 accggcacgt ctacgataat cagggtatac tcgtcttcaa tggtaatacg agacatttct
    19081 tccgcatcga gcggtgctcg aaggtcggca atatcaatat cgaaggtgtt ggcgatttcg
    19141 agtgattcat tttgagtcgg attgacgaga ttgatccaag tacccggttc aagcgtatcg
    19201 atctctttaa attcagttgt tgtagagaga aaaacttgtt tcatatccct tatcctttct
    19261 catttttcag attttttcac actgtactat tatactacaa aatcggcctt ttgggtaata
    19321 gaatctcact ttttttggta taatggtaag caataatgga ctagaaagaa caaagatgca
    19381 agataaaatt gtcattcatg gggcgcgtgc ccataattta aaaaatattg atgtggagat
    19441 tccgcgagac aagttggttg tcgtgactgg cttgtcaggt tcagggaagt ccagtttggc
    19501 ttttgatacc ctctatgcgg agggacaacg tcgctatgta gagagtttgt ccgcctacgc
    19561 tcgtcagttc ttgggaaata tggaaaaacc agatgtagat gccattgatg gtctcagccc
    19621 agctatttct atcgaccaga aaacgactag caaaaaccct cgctcgacgg tgggaacaac
    19681 gactgaaatc aatgactatc tgcgtctcct ctacgcgcgt gtggggacgc cttactgtat
    19741 caacgggcat ggggctatca aggcttcttc tgtggagcaa atcgttgata aggttttgga
    19801 gttacctgaa cgccagcgct tgcagatctt gtctcctgtc atccgcaaga aaaaaggcca
    19861 acataagagt gttatcgaga aggttcagaa agacgggtat gttcgtgtcc gtgtggatgg
    19921 ggaagtctat gatgtgaccg aagtgccaga gttgtctaag agcaagcaac acaatatcga
    19981 tgtcgtggtt gaccgtattg ttatcaagga gggcattcgt agtcgtctct ttgattccat
    20041 tgaggctgcc cttcgtattg cagaaggtta tgtcattatc gacaccatgg acaactctga
    20101 gttgttgttc tctgagcatt atgcctgtcc agtttgtggt tttactgtcc cagagttaga
    20161 gcctcgtctc ttttctttca atgctccttt tggctcttgt agtgagtgtg acggcttggg
    20221 catcaagctg gaggtggata ctgatttggt agtgccaaat gccagcaaaa ccttacatga
    20281 gggagcgctg gcaccttgga atcctatctc atccaactac tatccaaaca tgctagagca
    20341 ggccatgacg gcttttggag tggctatgga taagcctttt gaggacttgt cagaagaaga
    20401 caagaacttg attctctacg gctcagatgg taagaaattc catttccact atgagaatga
    20461 atttggtggc gtgcgcgata tcgacattcc gtttgaggga gttatcaata atatcaaacg
    20521 tcgttaccat gaaaccaata gcgattacac tcgcactcag atgcgcctct acatgaatga
    20581 gctgacttgc ggaacctgtc acggttatcg tctcaatgac caggccttgt ctgtccgtgt
    20641 gggtggtgag caagggccac atatcggaga aatttcagac ctgtctatcg cagatcactt
    20701 ggacttggtg agccagttaa ctttgtctga aaatgaagcc atcattgctc gtcccattct
    20761 caaggaaatc aaggatcgtt tgaccttcct taataatgtg ggtcttaact atctaaccct
    20821 gtcacgttca gcaggaaccc tttcaggtgg ggaaagtcag cgcattcgtt tggcaaccca
    20881 gattggttcc aacctatcag gcgtcctcta tatcctagac gagccgtcaa tcggtcttca
    20941 ccagagagac aatgaccgcc tgattgccag tctgaaaaag atgcgtgact tgggcaatac
    21001 tcttatcgtg gtggaacacg acgaagatac catgcgtgaa gctgattatc tgattgacgt
    21061 tggtcctggt gccggtgttt ttggtggtga gattgttgca gcaggtacac ctaagcaagt
    21121 ggctcgcaac agcaagtcta tcacaggtca gtacttgtca ggcaaacgtg tcatcccagt
    21181 accagaagag cgccgtgtcg gaaatggtcg ttttattgaa gtgataggag cgcgtgagaa
    21241 caacttgcaa aatgtcacgg ctcgctttcc actaggaaaa tttatcgcag tgacaggtgt
    21301 gtcgggttca gggaaatcga ctctaatcaa cagcattctc aaaaaagcca ttgcccagaa
    21361 gctcaaccgt aattcagaca aacctggtaa gtttaagact attacaggga ttgagcatgt
    21421 cgaccgtttg attgatattg accagagccc tatcggacgg acgccgaggt ctaacccagc
    21481 tacctataca ggagtttttg acgatatacg tgaccttttt gctcagacaa atgaagccaa
    21541 gattcgaggc tacaagaagg gacgcttcag tttcaacgtc aagggaggtc gctgtgaagc
    21601 ttgctcaggt gacgggatta tcaagattga gatgcacttc ttgccagatg tttatgtggc
    21661 ttgtgaagtt tgccacggaa cccgctataa cagtgaaacc ctagaagttc actacaagga
    21721 aaagaatatt tcgcaggtct tggatatgac ggtcaacgat gcggtagaat ttttccaaca
    21781 cattccgaaa attcaacgca aactccagac catcaaggat gtagggctag gctatgtgac
    21841 cttgggacag ccagctacca ccctttctgg gggagaagcc caacgtatga agttagctag
    21901 cgaactccac aaacgctcga caggaaaatc tttctacatt ctggatgaac cgacgacagg
    21961 gcttcataca gaggacattg ctcgcctgct caaggtttta gctcgctttg tagacgatgg
    22021 caatacagtc ctcgtcatcg agcacaatct ggatgttatc aagacggcag accatatcat
    22081 tgacttggga cctgagggcg gtgtcggtgg tggaaccatc atcgtaacag gaactccaga
    22141 agaagtagct gccaacgaag ccagctatac aggacactat ttgaaaggaa agttacatca
    22201 tgaataaacg cgtacaagca tttctagcta aaatgcaaga aaaagaacta gatggtgtca
    22261 tcatcaacaa tcttaaaaac gtctattatt tgactggttt ttggggctca aacggaacag
    22321 tctttatcag ccgtgaccgt caggtattag tgacagactc tcgctatatc atcgcagcta
    22381 agcaagaaac cagtggtttt gagattgtgg ctgatcgtga tgaattggct gtcattgcag
    22441 gaattgttaa ggacatgggc ttgactcgta tcggttttga agatgagatt tcagtgtctt
    22501 attaccaccg tatgcaggca gcttttgcag gtttgaactt gcttccacaa actcagtttg
    22561 tggaaggtct tcgtatgatt aaggatgagg cagagattgc agcgattcgc aaggcttgtt
    22621 ctatctcaga ccaagctttc cgcgatgcgc ttgactttat caaaccagga aaaactgaaa
    22681 ttgagattgc caacttcctt gatttccgca tgcgtgagtt gggagcatct ggcttatctt
    22741 ttgatacgat cctagctagc ggtatcaatt cttctaaacc ccatgcccat ccaatgcaca
    22801 aaccagtgga gttgggagaa gccattacca tggacttcgg ctgtctctat gaccactatg
    22861 tcagtgatat gacccggact atctatctag ggcatgttag cgatgagcag gcagagattt
    22921 acaatacggt tctaaaagct aaccaagcct tgattgacca agctaaggca ggcttaggtt
    22981 tccgtgactt tgacaaaatc cctcgtgata ttatcattga ggcaggttat ggtgactact
    23041 ttactcacgg cattggccac ggtattggtc tggatatcca tgaggaaccc tactttagtc
    23101 agacttctac agaaactatt aagacaggta tggccttgac cgatgaacca ggtatctata
    23161 tcgaaggcaa atatggcgtt cgtatcgagg atgatatcct gattacagag acaggttgtg
    23221 aattattgac cctagctcca aaagagttga tagtcattta gttgtttgtc aagaaaaaag
    23281 tacgaaaatg acgaaaaaag tcaaaaaaaa tt
//
LOCUS       DAVBCA010000031        22207 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.031, whole genome shotgun sequence.
ACCESSION   DAVBCA010000031 DAVBCA010000000
VERSION     DAVBCA010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22207)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22207)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22207
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.031"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(71..2029)
                     /gene="ftsH"
                     /locus_tag="VQU19_001180"
     CDS             complement(71..2029)
                     /gene="ftsH"
                     /locus_tag="VQU19_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HET2480435.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEETGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMFGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNREIHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDEK"
     gene            complement(2045..2587)
                     /gene="hpt"
                     /locus_tag="VQU19_001181"
     CDS             complement(2045..2587)
                     /gene="hpt"
                     /locus_tag="VQU19_001181"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HET2480436.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKAREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            complement(2591..3868)
                     /gene="tilS"
                     /locus_tag="VQU19_001182"
     CDS             complement(2591..3868)
                     /gene="tilS"
                     /locus_tag="VQU19_001182"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HET2480437.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEEEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ESIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            complement(3865..5133)
                     /locus_tag="VQU19_001183"
     CDS             complement(3865..5133)
                     /locus_tag="VQU19_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HET2480438.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKAWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            complement(5253..5621)
                     /locus_tag="VQU19_001184"
     CDS             complement(5253..5621)
                     /locus_tag="VQU19_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HET2480439.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            complement(5614..5880)
                     /locus_tag="VQU19_001185"
     CDS             complement(5614..5880)
                     /locus_tag="VQU19_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HET2480440.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            complement(5938..9447)
                     /gene="mfd"
                     /locus_tag="VQU19_001186"
     CDS             complement(5938..9447)
                     /gene="mfd"
                     /locus_tag="VQU19_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HET2480441.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYAQHAFIHQLKENG
                     YQKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERELAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPIQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTSICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNIDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKEFKEENSI"
     gene            complement(9448..10017)
                     /locus_tag="VQU19_001187"
     CDS             complement(9448..10017)
                     /locus_tag="VQU19_001187"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HET2480442.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVKYYLQEKNFEKTMQRYNG"
     gene            complement(10088..11203)
                     /gene="ychF"
                     /locus_tag="VQU19_001188"
     CDS             complement(10088..11203)
                     /gene="ychF"
                     /locus_tag="VQU19_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HET2480443.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIIEFRFNV"
     gene            complement(11287..11481)
                     /locus_tag="VQU19_001189"
     CDS             complement(11287..11481)
                     /locus_tag="VQU19_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HET2480444.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            complement(11546..12682)
                     /gene="dnaN"
                     /locus_tag="VQU19_001190"
     CDS             complement(11546..12682)
                     /gene="dnaN"
                     /locus_tag="VQU19_001190"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HET2480445.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            complement(12841..14202)
                     /gene="dnaA"
                     /locus_tag="VQU19_001191"
     CDS             complement(12841..14202)
                     /gene="dnaA"
                     /locus_tag="VQU19_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HET2480446.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYNYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            complement(14415..15173)
                     /locus_tag="VQU19_001192"
     CDS             complement(14415..15173)
                     /locus_tag="VQU19_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HET2480447.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            complement(15231..16412)
                     /locus_tag="VQU19_001193"
     CDS             complement(15231..16412)
                     /locus_tag="VQU19_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HET2480448.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLKSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVVVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            16595..17074
                     /gene="rlmH"
                     /locus_tag="VQU19_001194"
     CDS             16595..17074
                     /gene="rlmH"
                     /locus_tag="VQU19_001194"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HET2480449.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            17118..17191
                     /locus_tag="VQU19_001195"
     tRNA            17118..17191
                     /locus_tag="VQU19_001195"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17152..17154,aa:Arg,seq:tct)
     gene            17356..17481
                     /gene="comC"
                     /locus_tag="VQU19_001196"
     CDS             17356..17481
                     /gene="comC"
                     /locus_tag="VQU19_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HET2480450.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRLSKFFRDFILQRKK"
     gene            17502..18827
                     /locus_tag="VQU19_001197"
     CDS             17502..18827
                     /locus_tag="VQU19_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET2480451.1"
                     /translation="MDLFGFGTVIVHFLIISHSYHFICKGQINRKELFVFGAYTLLTE
                     IVFDFPLYILYLDGLGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDEDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            18824..19576
                     /locus_tag="VQU19_001198"
     CDS             18824..19576
                     /locus_tag="VQU19_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2480452.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            19628..19699
                     /locus_tag="VQU19_001199"
     tRNA            19628..19699
                     /locus_tag="VQU19_001199"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19661..19663,aa:Glu,seq:ttc)
     gene            19705..19778
                     /locus_tag="VQU19_001200"
     tRNA            19705..19778
                     /locus_tag="VQU19_001200"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19739..19741,aa:Asn,seq:gtt)
     gene            complement(19819..20361)
                     /locus_tag="VQU19_001201"
     CDS             complement(19819..20361)
                     /locus_tag="VQU19_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HET2480453.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            20540..21307
                     /locus_tag="VQU19_001202"
     CDS             20540..21307
                     /locus_tag="VQU19_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HET2480454.1"
                     /translation="MIGISLIPDLYNIIFLSSMWDPYGQLSDLPVAVVNNDKEASYNG
                     NTMAIGKDMVSNLKENKTLDFHFVDEEEGKKGLEDGDYYMVVTLPSDLSEKTTTLSNI
                     QSTAAYQSLTSEQQTEISDSVSQNSTDSIQSAQSIVALVQDLQGSLENLQNQSSNLST
                     LKNQSNQVSPITSTSLIGLSSGLTEIQGDVTSKLVPASQSIASGVNAYTTGVDKVSQG
                     ASQLSEKNATLTGSLDKLVSGSNTLTQKSSRLTAGVG"
     gene            21392..22072
                     /locus_tag="VQU19_001203"
     CDS             21392..22072
                     /locus_tag="VQU19_001203"
                     /inference="COORDINATES: protein motif:HMM:TIGR03057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HET2480455.1"
                     /translation="MADGSGKLAEGGTKLTSGLEDLQTGLASLGQGLGNASDQLKSVS
                     TESKNAEILSNPLNLSKTDNDQVPVNGIAIAPYMISVALFVAAISTNMIFAKLPSGRH
                     PESRWAWLKSRAEINGIIAVLAGILVYGGVQLIGLTANHEMRIFILIILTSLVFMSMV
                     TTLTTWNSRIGAFFLLILLLLQLASSAGTYPLALTNDFFRSINPWLPMSYSVSGLRQT
                     ISINKSFS"
BASE COUNT         6867 a         4089 c         3633 g         7618 t
ORIGIN      
        1 cattttctcc attctgttcc ctttagctcc taaactgcac aaaaaagaga ggctccagcc
       61 tctctcaggg ttatttttcg tcattcattt ttgactttac ttcatcatag gatagtgcat
      121 gagattcctc ttctactgct tcaggcatct ttcctgtttc gtaaagagct ttaatttgtg
      181 tactatccaa tgtttcgtat ttcaataatg cttctgcaat taacttgtga atttcacgat
      241 ttgactgaat aatttcagca gctttatttc gtgcctcatt taataatgaa cgaacctctt
      301 catcaatttc ataagctgtt tgttctgaaa ttgatttttg aggactctgt gcaccaaaca
      361 tagcatggtt tccttcatat tgtactgggc caagtttttc actcataccg tactctgtaa
      421 ccattgcacg cgccatttgt gtcgcttgtt caaagtcgtt tgaagctcct gtagtttgga
      481 cattaaagat aatttcttca gctacacgtc cacccattaa gccagccaat tgctctttca
      541 tatcttcttt agatagaagc atttgatcct ctttaggaag tgcaatcatg tatccgcctg
      601 cacggccgcg tggtacaatt gtaaccttat ggacaacgcg agcattcgac aagactagac
      661 caacaatggt atgtcctgcc tcatggtaag caaccaattc tcgttctttt tgtgaaactg
      721 tcttatcttt cttagaaggt ccagcaataa ctctatcttc tgcttcatca atatctgaag
      781 catcaattat cgatttattg cgacgagcag caactaaagc tgcttcattc aagacattct
      841 ctaaatcagc accaacaaag cctggagttt gttgagccac taatttcaaa tcaacatctt
      901 ctgctaaagg cttgttctta gcgtgaactt tcaagattgc ttcacgacct ttaacatcag
      961 gacgaccaac caatactttt ctatcaaaac gtcctggacg caaaagggca ggatcaagta
     1021 catctgaacg gtttgtcgca gcgatgacga taatcccttc atttccctca aaaccatcca
     1081 tctcaatcaa aagttggttc aaggtttgtt cacgttcgtc attacctccg ccgagaccga
     1141 ctccacgttg acgtccaaca gcatcaattt catcgataaa gatgatagct ggtgctgctt
     1201 ttttggcatc ctcaaaaaga gagcgaacac gactagctcc aactccgaca aacatttcta
     1261 caaagtcaga acctgagata ctaaagaatg gaacacctgc ttctccagcg actgccttag
     1321 caagcaaagt tttacctgtc cccggaggtc cctccaaaag aacacctgct ggaatacggg
     1381 ctccaagttt tgtgaatcgt tttggatctt ttaagaactc aacaacttca actagttctt
     1441 gtttttcttc ctcagctcca gcaacatctg aaaatcttac tttaatatct tctttatttg
     1501 ctgctttagc cttactacgt ccaaaactca ttggattacg gccattgcct cctcccatat
     1561 ttcccatcat agagaatagg aagaagaata gaattccaaa tggcacaatg gatacgagta
     1621 gattaatcca tataccactt gaactttcat gcttaacagt tacttctgct ttatggtcag
     1681 tagcaagttt ttgcaattct gatacggtag tatctgcagg aagaatagtg ctggtaaatt
     1741 tctctacctt agtaacagat ggcgtgaaaa actgaatacc tgtttcttct ttacttgttt
     1801 taggattttt atagacacca gaaacttcga taacactacc atttggttgg taagttaatt
     1861 cttttacatt accatcggta atttcttgta ccaactcagt atagttgatt tgctgacttc
     1921 ctcctgagtt attcccagaa tagaaatact ggaatcctgt cacaaggaaa aagataaata
     1981 ataaccatag aaaaggattt ttaattaaac cattattttg ttttttcatt aaagattatt
     2041 ctttctaatt tgaatacact tcctctttca atactccaat ataaggaaga ttacgataat
     2101 tttctttgta gtctaaacca taacctacta caaactcatt tgggatagta aagcaggtat
     2161 agtctgcctc aatttctaca acacgtcctt ctggtttatc caacaaggtt gcaattttaa
     2221 cagaagctgc ttctcttgct ttaaacatat ctcgcaaatt cttcaaagtt tgacctgtat
     2281 caatgatatc ttctacaaat agaacatgtc ttcctttgat atcttgagtc acatcttgtt
     2341 taatattgat aacaccacta cttgctgttc caccatggta gctagaaacc atcatgaagt
     2401 ccatttcaat atgtgtatca atatgtttga ccaattcagc cataaaagga atagatcctt
     2461 ttaaaatccc aactaagatt ggattttttc ctgcatagtc tttagttaat tgagcaccta
     2521 gttttttagc tgcttctgta atttcatcgt gtgaaacgag gactttttta atatcgtttt
     2581 ctaacatttt ttacctatct attttttcta tataaagtac agtgttcatt atatcatttt
     2641 tcgttttttt actcaaatta ttggtcgcaa ttcccaaaat tgagacaatt tcaccaaatt
     2701 gctcaataat aagagcagag tttctctttt ccatagggat tttcaaatca ataaataaac
     2761 gtctgagttt ttttctatgc ccattttgaa tcaaaacatc tcctgttttt cgatgacgaa
     2821 tgtgtatgga tgtttcacgt gaaacaggta tttgttgaat tgattcacct tctaatggaa
     2881 gtccaaagga aaataaatat ccttgataag ctacctgatt ttgatagtgt aacacaagtt
     2941 catcttcctc ttcatcagcc tgcggactga ttttacaaat ctgaaactgt tggtactctt
     3001 ttatcaattc atagccattt ttaatcggat gacgatactg gcttttagat tttaaaatct
     3061 gctgaacttc agcaaactga gcttttgtaa gattcaaatc tggaaaacga ttcagataag
     3121 tttgaagtaa aactctttgt gtagactcag agtaagaaaa taactgctgt aaatcttcca
     3181 cattaatatt gttagataat tcagctattg ccaaatcata atctaaaatt tcattgccaa
     3241 tgcctaagat tgcatcccta aatcgaggat tttctttttc caattctggt aagtaagagt
     3301 ttcgaatacg atttcgaaaa taatgattct cctgatttga tgtatcttca aagtgaaaaa
     3361 ttgatggaaa gtcttttttc tgaaaatgca agaagggacg aatgatttct atctctccga
     3421 ctacttgctt ctccttaatt cctgatagat agcgcaagcg agttcctcga atcaagcgca
     3481 tcaaaatcgt ttccacctga tcatcagcat ggtgggcagt gactaaagct gtcgcacctg
     3541 tctttttcat gacctcttga aaaaaatcat aacgaaaatt tcgtgcacgc gcttctgaaa
     3601 attctcctga aaaattgctg atataaatag gaagctctgc ttcagcagcc aacttcctta
     3661 attccttttc ttcccaatct gattcaattc tctgcttatg attcacatga gctagaatca
     3721 attcaatctc taactctttt tgataagtag acaatacctt aaatagaaac atggaatcta
     3781 atccaccaga aagagctaga accgccttag catgcttttt gaaatatccc ttcttgagaa
     3841 aatgatttaa aaaatctggt tccctcattt tagaacctca taaacatcct tggctatctt
     3901 agaaatcgta tcataatcag aattcttagt gaaaatagaa agaataaatg gagaatctgc
     3961 atagacaaca cccgtatcat gcttaaattc atccgcatct ccaattttat gagctacttt
     4021 aacagaaaca cctttggcaa ttcgctgact atcaaaatct gttttagtca aagactctaa
     4081 cacaaatcca ttttgattat aaatagcttc cataaacttc ccggccatct tagaagaaat
     4141 caatttttct tttggatccc aatcatctcc cataatggca gacatcttgg atttgaatgt
     4201 ggcatcagat tggtttgaaa tgtaatatcc caatagatta tgagctacat tatcagattc
     4261 ttttgatact ttcgtaatta aatcctttaa agaatattct ttattatctt cttttttagg
     4321 aagactacca cttccctctg gtttataaga acctggaaaa tcattgactg cagatacgta
     4381 ttttacagtc gtatctaact gataaagacc ctcatttatt ttttcttgcg tataatagag
     4441 ataagagagt ttcaaaacgc tggctgcata catcttttca tcttgattga taccagcttc
     4501 ttttccagta gtcagttgct taacataaat agagaaagaa tctttctgat atttttcaga
     4561 taacatttct tgaactttac tcatccgatt atcttcttca gaagttgatt ctttagctac
     4621 ccatccagcc tgatcaatat gtagaaattc tcttccttct acaaacatgg tcttgtcgat
     4681 tgatacttgc gaataagctg ataaggatga tttcacttct tttaaatcat aaggactatt
     4741 gtacagttta aagtcagatt ctaaccatgc tttttttatt gttggagtta cctctgattg
     4801 atcatataaa aatcgtttgt ccgcagctat aaattgatga tttgatagct taaatactgg
     4861 aattccttgt ttatttaagc gccactcggt tatttgaaaa cttgttttgg gagtcaattt
     4921 cccagattcc actactaaat cttcattcgc ataaacagga acctctccat aaaccatggg
     4981 agaacttaat ttttctctaa aataaatacc aaagtcagat tgtgaaaggt aataaatttc
     5041 tttcgaagta tagacgactt ctttttctgt gctaacgact tttgaaatgg tcaaaaaact
     5101 tggtagcaac aaaataatta agaatttacg cattcttcct ttccttttct tcttgtaaac
     5161 gcaataattg atttttatca gccaattctt ccagcttttc atctgacaaa ctcaaaaatt
     5221 gctctattac gtctaataaa ttttccattt tatcaccttt gaagcaagtc aggaatcgta
     5281 taaacttttt ccctcgactt agaataatag tacttcgctc gtgtatattt ggcagcataa
     5341 tcttcatctt tcaacttggt agcaaatgct gtctccttat ccttttcatc actcaaagtt
     5401 tgatactgag tttgcaagtc tgctaattgc tgacgtcttt ggagtaattg ctgataactc
     5461 tgcgctaaat taaaagttgg caagataaat aatagcataa tcaaaatcaa tacccctccc
     5521 ataaaacgat tccgtttttg tcgttctttc atcaggtagc gacgacgttg gtattcattt
     5581 tgaataaaag aattattcaa ttgtacaata tttttagaca ttttcttcta cccgtgtttc
     5641 actgataatt tcatacattc ctgctgcatc ttcttttttt gtactatctt tcatctctag
     5701 tacttttaca agcagcaact tattgccaaa gcgaatttca acttggtcat taactttcaa
     5761 gtccgttgaa cttttggcca agattccatt aaccttgatt ctacctttat ctgctacttc
     5821 ctttgcgact gtacgacgct tgataattcg cgatactttt aaatatttat ctaatctcat
     5881 ccttattacc tcaatttatt attgtaccat ttttatctat tttatagaag aaaaatatca
     5941 aatggaattt tcttccttaa actcttttat ctctaataaa ctttctccaa aaatcagcag
     6001 accttctaaa atttcataat ctttcttatt ttggacatca aatacaagct ccattaatcc
     6061 cttattctca gcgatgcctg cttttaagtt cgttacggat aaagctttaa aataatcttg
     6121 agctaaaaac aatcgttgag tgactttttc aaattgaatt gtaattttat tatcttttct
     6181 ttccacacgt tgaacaaaga ccttgtccaa gtatgattta accaaaccaa tctctaaaag
     6241 ataggctact acatctgggt attctccaaa acggtctatc aactcctctt gtaactcttc
     6301 ataattgaca cggttgtcaa tttgacgaat tttcttgtaa atttcaatct tatgtcgttg
     6361 atcagaaata taagtatcag gaagataggc atcaatttgc aaaatcaact cagcattccc
     6421 tttggttctt gtgttagcgt tagcattacc gtttcgttta gcaatagctt cctctaataa
     6481 ctgcgaatac aattcaaaac caacagaatc aatgaaacca gactgggatt ttcctaaaag
     6541 atttcctgct ccacgaatcg aaagatctcg cattgcaatc ttaaagccag agcccaattc
     6601 tgtaaatcct ttaatcgctt ctaatctctt ttcagagact tcactgattg atttttctgg
     6661 acgatacatg agataagcat aagcaatacg attactacga ccgactcttc ctcttaactg
     6721 atataaggtt gacaagccca tatggtccgc attttcaata aataaagtat tagcatttgg
     6781 aatgtccacc cctgtctcaa taatagtagt cgtcaccaag atatcgtatt gtccctcaat
     6841 aaagtctaat agagtatttt ccaactggac ttcactcatt cgaccatgaa catatccaat
     6901 cgaagcctcc ggaatcaact cctgtaattc tgaaaccttc tgaacaattg tgtcaacttt
     6961 gttgtaaaga taataaactt gacctccacg ctccatttca cgcaagacag catcacgaat
     7021 gacactatca ttcttttcca aaacataggt ctgaacagga tagcgattag tcggcggagt
     7081 ttcaataaca gataaatctc tgattcccag catagacata tggagggtac gagggattgg
     7141 cgtagcggtc aaggttagga catccacttg tttcttcagt tctttcaaag tttccttatg
     7201 cttgacacca aatcgctgtt cctcatcaat aatcatcaag cccaaatcag caaacacaac
     7261 atcttttgac aaaacacgat gtgttccaat caaaatatcg acttgaccgt ttttcaattt
     7321 ttcaagtgtt gcagtctgct cttttttact tctaaagcga ctcaacacat caatattaac
     7381 tgcaaaattt tggaatcgtt ccttaaaatt cgtatagtgc tgttgcgcta aaaccgtcgt
     7441 cggaactaga atgacaacct gtttgtgatc attgactgct ttaaaggctg cacgcatagc
     7501 aacttcagtc tttccaaaac caacatcccc aactaaaagt cgatccattg gctgagaagc
     7561 ctgcatatcc ctcttgattt cctcaatact acgaagttga tcatccgttt caacataagg
     7621 gaaagcatca tcaaaggcat cttgatcatc atcatcagct gagaaagcaa aacccttcaa
     7681 ctgactacgt tcagagtaga gtttgattaa atcatcagct atatcctcta cctggttctt
     7741 aaccttttgc ttggcctttt taaaatgacc gtcatttaat ttattgagtt ttggagcttt
     7801 accatcactt gaaatatatt tggacagtag atgaatctgt tccacgggga tagaaatttg
     7861 atcaccattt tggtattgga cactgacata atcgcgatga attcccttga tttcaatggt
     7921 ttcaattcct agatattgac caatcccatg gatatgatgg acaacatagt cccctttttc
     7981 aagttcattg taatctttta atctctctgc atttgaaaca tgttgtcttc gaaaacgacg
     8041 ctttaatttc ttttgaaaaa tctcatgttc agttatcaat aaaatctttt catctacaaa
     8101 atgaaaacca tgtctgagat taccctctat taaatttaca gattctttac agatacttgt
     8161 cttatctcta gaatccaatt taatctgata ttcctctaac atatcctcca atgttttact
     8221 tcccattgaa ttgctagact gcagaataat ggtgtaatcc atttttttat atcgttcaat
     8281 ttcttctttt agaaaagaaa actgattgaa aaattcctgt ataggatatt gattgaattg
     8341 ataaattttg tcaaatttga gatttcctaa acccttttga agattagaga aaaaggtcac
     8401 tggactttgt tttttataga tttgttcaat atcagaaaaa tactgcatat cagaaaatgc
     8461 tttactattc tgtaattctt ctgtaaagta ctgcgctaat tctctttcaa agacttcata
     8521 ctgattcatc aatttttgat aatcatcaaa gaatattgga gtatcttttt caatataatc
     8581 aaagacagtc catgtcttat catagcacaa agataaaaac ttccgagaat ctgcatgact
     8641 ttgtttttgg tgaaaacttg aaagaatttc ttctaggtat gatttcaaaa taggtgataa
     8701 agtttttgaa atttgttttt ctaaagctga ctgtcctcgt tgataatcct tttctctcaa
     8761 aagcatatca ctagctggaa agatagtgag ttctgtctta ttttctttcg ataattgtgt
     8821 ttctacttca aatgacctga taccatcaat ttcatcacca aaaaactcaa ttcgacaagg
     8881 ttctaactgg gatatttcaa aaatatctaa aatatctcct cgaagactaa attcgccctg
     8941 agtttgtact tgagtaactt tttgatagcc attttccttt aactgatgga taaacgcgtg
     9001 ttgagcatat tcttcaccaa ctgagatttt tacaatacta tctttgaatg cattgggaga
     9061 cggtaaaatc aatcgacttg ctgcgatatt acaaactaaa atccctttct tagatgaatc
     9121 agtcaaaaaa cgcaaggctt caacccgtga aataattttt tcctgtgaag acatcaaaaa
     9181 ctccaccata ggagcatcat ctaccaaaaa tggatagacg agttcctcac ccaagataga
     9241 aataagatca ctaacaagtc cttctgcttc tccataagtt gacgtcaata acacaatcct
     9301 atcttctttt tctaaactgc ttgcaattgc aagagcctta gtagatgttg ataaaccaag
     9361 tattagttgt cttttcttat ctgttaaatt ttgatgccat tttttaatct gatcattttc
     9421 tgagaataaa tctaataagg tcaccattta tccgttatac ctctgcattg ttttctcaaa
     9481 atttttctct tgtaaatagt attttacaga atcgtcaact ttgtcaacag actgtaaaat
     9541 accgatataa tcatccctgt caaacttact caaaacatga tgaacaactg acataccatt
     9601 tttaggtctt ccaattccaa tcttaacacg gttaaagacc tgagttccta tatgttgaat
     9661 aatagacttg ataccattat gaccacctgc tgagcctttt gctcttaaac gaattttccc
     9721 aacttccatg tcaagatcat cgtaaatgat aagtaaatcg tcaatatcca aaccatagta
     9781 agttaataaa gcatgaactg cttttccact ttcattcata aaggtcgttg gtttaaccag
     9841 ataaattttt tctccattta ggaaaaagga tgctaggtca gcttgaaata tcttatcgtg
     9901 tgtaaaagtg acattctgtt tcttcgctag ttgatcaatc aacataaaac caacattgtg
     9961 ttttgtttca aaatatttat cccctggatt tcccaaacct acaagtaatt tggtcattta
    10021 tttttccttt caaaagccaa aagggttgga atttttttcc aacctaattg acaccattta
    10081 ttaattttta gacattaaag cggaattcta tgatgtcgcc atcttgaacg atatattctt
    10141 ttccttcttc acgcaagcgt ccagcttctt ttacggcctt ttcagatccg tatttcacta
    10201 gatcttcata tgacatggtt actgcacgaa taaagccttt ttcaaagtct gagtggataa
    10261 taccagctgc ttgaggagcc ttcataccac gtttgaaagt ccaagcgcga acttcttttt
    10321 caccagctgt gaagtaagtt cccaatccaa gcaagtggta agctgcacgc gtcaacttat
    10381 ctacacctga ttctgtcaaa ccaatggctt caagaaactc ttttttatct tcatcatcca
    10441 attcagaaat ttcttcctca gcacgcgcag aaataacgac tacttcagca ttttctgtcg
    10501 ctgcaaattc acgaatttgt ttgacatagt cgatagagtc aggttctgaa accacatcct
    10561 cgtccacatt agctacataa agaactggtt tagtcgtcaa aaggaaaaga cctttgacaa
    10621 ccttttgttc ctcatctgta aattcaatgg tacgagctga tttcccgtct tctaggactg
    10681 gtttaatctt ttgaagaaca ttgaattctg ctactgattc tttatctttt tgcgtacgtg
    10741 ccatcttttc tacacgcgca tatcgtttgt tcactgattc taagtcagca agaattaatt
    10801 ccagattaat tgtatcaata tctgcaagtg gatctacaaa ggcgtcttca cgtccttgct
    10861 cgcgcatcac attttcatca tcaaaagcac gaactacgtg aacaatcgca tctacttcac
    10921 gaatattggc caagaattta ttccctagcc cttctccttt tgaagctcct tttacaatcc
    10981 ctgcaatatc cgtaaattca aatgttgtgg gaactgtctt tttaggagtt atcatttcag
    11041 ttagtttttg taggcgttca tctggaactt ccaccattcc aacatttgga tcaatcgtcg
    11101 caaatgggta gtttgctgcc tctgctcctg cttttgtaat tgcattaaat agtgttgatt
    11161 taccaacgtt tggcaaacca acgatacctg ctgtcaaagc catatttctc attctccgtt
    11221 ttcatttcaa tccctaatat tataacacaa aaagggataa agtgctaacc ctctaactaa
    11281 gggttctcag tcaataattt tattcatttt tcgctcaaaa tcatatcgcc ccatcatgac
    11341 aacatgctca caattactgc attttatttt gatatctgct cctacacgtg taatttccca
    11401 acgattagcc tttttaccag tcgacttgat tgtacaagcg tgtgattttt tcatctcaac
    11461 aaaatttcca acttgataca tactactctc cttttctttt tcgattatat cataaaagag
    11521 gcgagccagg ctcaacctct ttcacttaat ttgtacgaac tggtgtaatg agctgcatga
    11581 agtcttcgtc agtatctgct ggcacaagag taaatggacg aacagctgag ataaagctaa
    11641 tggtcacctt ttcgctattt aaagctttaa gagaatcaat caagtaagtt gggttgaaac
    11701 taatggtcaa atcttcacca gtaacctgat cagtatcgat ttcttcgttt actttaccaa
    11761 cttctggaga gtgaacatgg gcgctaacaa ccccatcctt aatttcaagt ttcacagtac
    11821 cattttgagt cgcacttgat aaaagacggg cacgctccat tgactggcgt aagtttacca
    11881 cattaaaagt aatagtagtg ttaaagtctg ttggaatcaa gcgatctgta tcaggatagt
    11941 ttccttctag gagacgagta tagaagctaa tattttcgct tctaaagagg atttggttat
    12001 tggcaaagaa aatctctaca gtttcgatat catctgtaaa taccgctgaa aattcgcgta
    12061 gagaacggct aggaattacg acatcaaaat catcactatt tttttcaaga gtcaattttt
    12121 tctggcttag gcgatgagag tctgttgcaa ctgtttttaa ctctttgtgt tgactcaata
    12181 cgaagtggac acctgttaaa atcggacgac tctcttgtgt acttgcagca aaggctgttt
    12241 cattaataat tttcttgagt aattttgttt caagtattaa aggagtgctt gctgaaattt
    12301 cttggattcg tggatattgt tcgctatctt ttccttttag ggtaatttct gatttgccac
    12361 tggttaaaac aatttgattt tgttcaattt ctttaaaatc aagagttaca tcaggtaaac
    12421 tagatactac attgataaag aaagaagctt caagaaggat cgaacctaaa gaagtaatta
    12481 acaaaccagc atcttcattt ttttgagaaa taaaattttc aattgaaatt tgaccatttg
    12541 aaccaattaa agtaatacct tcattggtca cgtcaatttt tactgttgat aaaataggaa
    12601 tggcattttt agaactaata gctctcttag tagtatttaa tgcttgtaga aataaatttt
    12661 tattaattga aaaatgaatc atggattctc ctttatttat ttttagtatt agaaagataa
    12721 tagtaataat agagtctgtg aaatctgtgg aaaacagcct ttaaacaagt catatcaagt
    12781 tttttagctt gtttaaaaaa tgtggataaa aaagataaaa aactaaaagt tatccacaaa
    12841 ttatttgatt ttctttttga ttgattcaat ttctaaacgt aaattatcgt cttgatcaat
    12901 caaagatttt attttggcat gggcatgaat gactgtggta tgatcttttc ccccaaattc
    12961 cttcccaatt tttggaagac tattatctgt tagttctcta gataaataca tggctacttg
    13021 acgggccaaa acaatatttt gaaggcgtct acttcccttc atttctttga tactaacacc
    13081 ataaaagtta ccaacttcag tttggatttt atcaattggg atgacgagca tttggctaac
    13141 atcttgtttg cgggctctaa tggcttctgc agcaatatca atagtgatat ccttgatttt
    13201 ttttactctg gcaattaaag tgatgtcgtt gatggctccc tcaagatctc gaacatttga
    13261 atcaaattgc ccagctaggt attctagagt atcactttgg aaattgtagc ctaaatgttc
    13321 cgttttactt tgtaaaatgg caatacgtgt ttcaaagtca gggggtgtga tagtttgtgt
    13381 caatccccaa ctaaaacgcg tgacaagcct ctcctcgagc ccttctagat gttttggact
    13441 acgatcactc gttaggacaa tctgtttttg cttgtcatga agggcgttaa aggtattgaa
    13501 aaattcttcc tgagttgcga ctttttttcc gctgagtgac tggatatcat cgattaacaa
    13561 aagatcaaga ctacgatagg tctttttaaa cttttccatt tccccaagtc ttaggtgatc
    13621 aagaaagtca ttaataaagc tttcggcagg gatatattta acacgcgcat taggaatatt
    13681 ttttagaatt tcatttccaa tagcgtttaa taagtgagtc ttaccaaggc ctggtcctcc
    13741 atagataaaa agagggttat aggtcagagc caaatcttca gagacagcta aagcggctga
    13801 cacagcccaa acatttccat ccccttgaat aaagttatca aaggtatact tttcttttaa
    13861 tcccgtatct gaataaggaa tagatactaa ctttggacta tagttataaa gagttaaatt
    13921 tgtagcttct tcaacttgtg agctagtcgt atcttgaggt ttggtgaaaa tatagtgggg
    13981 agttatttca gcgtcataaa tttcaaaacc agctactaca ataatatctt ttagttgttt
    14041 ttcccagacc atttccattt cagagcgagg tagaaatata gtggcaacat tttcctctac
    14101 cttgatgagt tcagcttgaa tagcatagaa atcatacatg gatcgagtca gtctttcttg
    14161 tgcaaattct aatatacgat tccaaaattg tttttctttc aatcctttct cctcctttac
    14221 tatttaaaag tttaatacta gagatatttt accatagata gcaagaattt tccacaagct
    14281 gtgaaaaata atccacaatg ttaccaaact ttatccacag gttggggata aaagaagaaa
    14341 ttattgattt attaagcttt ttattgaaaa acatagtgga taaccttgtg agataaaaaa
    14401 ataaaagaac agccttattt caggctgttg ataattctac tatattcttc ttgatttgaa
    14461 aaagaaataa tgatttttcc actgtctttt ttagatagtt taatttctac atctaatccg
    14521 agtagttttc ttaactgttt ttcttcattt tgtatgaaat gattagtttt ttgctgtttc
    14581 ttttgttttt tctctgtcag aagagcttct aatttcctta cagaaatatc ttcttctata
    14641 atccgttgaa agaaatagtc ttgttgttcc ttatttaacc caactaggga acgcgcatgg
    14701 gcttgtgata gtttgccatt ttctacttct gaaagaatct gttctggcaa ggaaagtaaa
    14761 cgaatggagt tgctgatata tggacgagac ttgcccatct tatctgcaat ttcagcatgg
    14821 gtgaatcctt tctctacgag agattcatag gcgcgtgctt cttctattgg gtttaaattt
    14881 tctctctgta aattttcaat aatggactgg accatcatct cttggtctga aatctgttta
    14941 acaacagctg ggatagaccg tagaccagct aaaagtgaag cccgatagcg tctctctcct
    15001 gcaaggattt cataaccaat aacaggagat tgacgaacaa taatcggttg aatgacccca
    15061 ttttctttga tagactgtgc tagttcatct agtttttctc tatcaaattc ttttcggggt
    15121 tgatagggat ttttttgtat atctgtgata gaaatcattt caaatttttc catgattcta
    15181 cactaacaca tcttttctct tatgtaaagc tttctttaca tagatgtcaa ttaagattct
    15241 aaatcacctg aactcttgtt aagtttgata gaggtagttt cttctttccc gttacgatag
    15301 taggttatct taatggtgtc tccgatagaa tggttgtaaa gagcactttg taagtctgtt
    15361 gatgaagcaa tctctttgtc atctactttt gtaattacat cgtatttttc aaggtgacca
    15421 ttggcaggca tattactttg taccgaacga acaactacac cagatgtaac attacttgga
    15481 atattgagtc ttctgatgtc gcttgtactc acattagata aattaaccat ctggattccc
    15541 aaagctggac gcgtcacttt tccgtttttt tctaactgtt caataatatt gatagcatca
    15601 tttgcaggaa ttgcgaaacc aagaccttct acagatgttc ctccatttgt agcaatttta
    15661 cttgaggtaa ttccgataac ctgcccttga atattgatca gtgggccgcc agagttacct
    15721 gggttaatag cagtatcagt ttggatggct tttgtagaaa tagcttgtcc atcttccgat
    15781 tttaaggata catttctatt gagactggat acgatacctt gagtgacagt atttgcatat
    15841 tcagaaccta acgggctacc gatggcaata gcagtttctc ctacagttaa cttactagaa
    15901 tcaccaaact cagctactgt tgtcactttt tctgaagaga tttttacgac agcaatatca
    15961 gagaaagtgt cagctccgac aatttctcca ggtactttag tcccatctga caatcgaata
    16021 tctactttgc tggcgccatt tataacgtga ttgttggtga cgatgtaagc ttctttatca
    16081 ttctttttat aaataactcc agatccttca ctagagattc gctgagaatc tgtgtcagta
    16141 tcatcattgc caaatacgct attttgtctg tttgccgaat aagtaataac agaaacaaca
    16201 gcatctttta ctttgttaac agcctgtgtt gttgaatttt cgttcttata ggcagtttgt
    16261 gtaatagtac tattgttgtt agagttgttt acactacttt tttgagttag ttgagttatt
    16321 gaaaaactac ccaaggctcc actaaaaaag ctaatgacga taacgactaa taattgaaac
    16381 cattttttgt aaaatgtttt tagatgtttc atatttgcct ccatatgttt gaattactga
    16441 aagtataaac tgactagctt aattataact taaacacaaa agttttacac aaactgtgga
    16501 taactctttt gaaactgtga ttttcttaat tgaaatctat tttttatttt gtgaataaga
    16561 tgtgaaaaaa tagagaatat gttagaatag agtcatgaaa attaaagttg taacagttgg
    16621 gaaactgaaa gaaaagtatt taaaagatgg tatcgcagag tattcaaaac gaatttctag
    16681 atttgctaag tttgaaatga ttgagttatc agatgaaaaa acaccagata aggccagtga
    16741 atcagaaaat caaaagattt tagaaataga aggtcagaga attttatcaa aaattgctga
    16801 ccgtgatttc gttattgtgt tagccattga agggaaaact ttcttctcag aagaatttag
    16861 taagcagtta gaagaaactt ctataaaagg attttctact cttactttta ttattggggg
    16921 aagtttagga ttgtcatcat ctgtaaaaaa tagagccaat ctttctgtca gttttggtcg
    16981 cctaacctta ccccatcagt taatgagact agttcttgtt gaacaaatct atcgcgcttt
    17041 tacgattcag cagggattcc cctaccataa atagaaaatt gacttttaat tgaatttttg
    17101 gtagaataat tgtattaggt ctcatagctc agctggatag agcattcgcc ttctaagcga
    17161 acggtcgcag gttcgaatcc tgctgggatc aatataatag caaagctggg aattttcccg
    17221 gcttttttct taaaaaagta cactttggga gaaaaaaatg acagttgaga gaattttatc
    17281 taaaacgaaa ttccattttg tataatggtt tttgtaagtt agcttacaag aaaaaacatt
    17341 ttaggagatt ttattatgaa aaacacagtt aaattggaac agtttgtagc tttgaaggaa
    17401 aaagacttac aaaagattaa aggtggggag atgaggttgt caaaattctt ccgtgatttt
    17461 attttacaaa gaaaaaagta atgaaataag gggaaagagt aatggattta tttggatttg
    17521 ggacggttat tgttcatttt ttaattatta gtcacagtta ccattttatt tgtaaaggtc
    17581 aaataaatag aaaagaatta ttcgtttttg gtgcttatac attactaaca gaaatagtat
    17641 ttgattttcc cttatatatt ctatatttag atgggttagg gattgaaaga tttttatttc
    17701 ctttgggatt atattcctat tttcgatgga tgaaacagta tgagagggat agaggactat
    17761 tcctaagttt actactatct cttttatatg agagcactca taactttctg tccgtaactt
    17821 tctcctctat aacaggagat aattttgttt tacaatatca tttcccattc tttttcgttg
    17881 tgacggtgtt aacctatttt gttacattaa aaatcattta ctatttccat ttggaactag
    17941 cctattttga cgaggactac ctttatcctt tcttgaaaaa agtatttttt gctttactat
    18001 tgctacatat tgtatctttc gtttcagata tggtaagtac gattaaacat ttgaatagtt
    18061 ttggaagtat tttgtcatct attgtcttta tctctctcct tttgaccttc tttgcaatga
    18121 attctcataa agttcaaatg gagaaagaga ttgctttgaa gcagaagaaa tttgaacaga
    18181 aacatttaca gaattacaca gatgaaattg ttggtctgta taatgaaatc cgtggttttc
    18241 gacatgatta tgctggaatg cttgtcagca tgcagatggc aattgacagt ggtaatttac
    18301 aggaaattga cagaatttac aatgaagttt tagtcaaagc aaatcataaa ttgcgttcag
    18361 ataagtacac ttactttgat ttgaacaaca tagaagactc agctttacga agtttggttg
    18421 ctcagtcaat tgtctatgct cgaaataatg gtgtagagtt tacactggaa gtaaaagata
    18481 cgattaccaa gcttccaatt gaactattgg atttggttcg tatcatgagc gttttattga
    18541 ataatgctgt cgaaggatcg gctgatagct ataaaaagca gatggaagta gcagttatta
    18601 agatggaaac tgaaacagtt attgtgattc agaattcatg taaaatgacg atgactcctt
    18661 caggagatct atttgcctta ggattctcca ctaagggaag aaatcgcgga gtcggattaa
    18721 ataatgtgaa agaactacta gataagtaca acaatattat tttagaaaca gagatggaag
    18781 gcagtacatt tagacaaatc attagattta agagggaatt tgaatgaaag ttttaatttt
    18841 agaagatgtt attgaacatc aagtgagact agagagaata ttggatgaaa tttcgaaaga
    18901 atcgaatatt ccaatatcat acaagacaac gggaaaagtc cgtgaatttg aagaatacat
    18961 tgaaaatgat gaagtaaatc agctttattt cctagatatc gatattcatg gaattgagaa
    19021 aaagggattt gaagtggctc agctcattcg tcattacaat ccttacgcta ttatcgtctt
    19081 tatcactagt cgatcagagt ttgcgactct aacctataaa taccaggtat cagccctaga
    19141 ttttgttgat aaggatatca atgatgagat gtttaagaag agaattgagc aaaatatctt
    19201 ctacacgaag agtatgttac ttgaaaatga agatgttgta gattatttcg actacaatta
    19261 caagggaaat gatttaaaaa ttccttacca tgatattttg tatattgaaa caacaggggt
    19321 ctctcataaa ttgcgcatta ttggtaagaa ttttgcaaaa gagttttatg gtaccatgac
    19381 agatattcag gaaaaggaca aacatactca gcgattttat tctcctcaca agtcattttt
    19441 ggtaaatata ggcaatatca gagaaattga tcgaaaaaac ttagaaattg ttttctatga
    19501 agaccatcgt tgtcctattt caagattaaa aattagaaaa ttaaaagata ttttagagaa
    19561 aaaatctcaa aagtgattga caattagcaa gaaattgata taatggttat atctgctaca
    19621 gatagaaggt ccgttggtca aggggttaag acaccgcctt ttcacggcgg taacacgggt
    19681 tcgaatcccg tacggactat tttatccgcc atagctcagt tggtagtagc gcatgactgt
    19741 taatcatgat gtcgtaggtt cgagtcctac tggcggagta tagataaaag ggaacacagc
    19801 tgtgttcctc tttttgtatc aatttgtatc accaagcatt ttcataagga agtctgttat
    19861 ttcttgagaa ctttcttttt ttccatgtgc aatccaagtt tggcagacac caaaaagtgc
    19921 atgagttaga tagatgctac tatattctaa ttcggtggta tttagattca gttgcataaa
    19981 tcgcttttgt aaatctgtac taagcatgat atgaagttta tttcgtaaga aattttggat
    20041 ttctttagtc ccattttcag aaagaagggc agccagaagt ggttctgact ctagatattc
    20101 aaaaacttct aaaatagcgt ctcttttgtg atgagcatgt ttttgaaaaa tatattcaaa
    20161 tgtatggaat agcttgcttt gatagtgctc aatcatatca tacttatcct tatagtgagt
    20221 atagaagctg gaacgactaa ttccggcttt ttctactaat ttgacagtag aaattttatc
    20281 aaatggctgt tccatcagta attgtaccat agcattttca atagttcgct ttgtttttaa
    20341 gcgtttgtta ctttcttgca tatttcctcc ttgtaaacaa attagactat atgtttaaaa
    20401 atagattttt tatcttgtaa tttagatttt ttaatgtata atctattata tcaaaatttt
    20461 agacaatatg tttaaaaaag gagaaactaa gtttaaagaa tggaaagcaa tttaaaaaaa
    20521 accaaccttt attattgtca tgatcgggat ttctcttatt ccagatctgt acaatatcat
    20581 atttttgtca tcaatgtggg atccatatgg gcaattgtct gacttacctg tggcagttgt
    20641 aaataatgat aaagaggctt cctataatgg taatactatg gcaataggaa aagacatggt
    20701 gtccaattta aaagaaaata aaaccttgga ttttcatttt gtagatgaag aggaaggaaa
    20761 gaagggattg gaagatggcg attactatat ggtagtgact ttaccaagtg atttatctga
    20821 aaaaacaact acattatcca atattcaatc gacagcagct tatcaatcat tgacaagtga
    20881 gcaacaaact gagataagtg attctgtatc tcaaaattca actgatagta ttcaatcggc
    20941 tcagtcaatt gtagctttag tacaagattt acagggaagt ttagaaaact tacaaaatca
    21001 atcttctaat ctttcgactt taaaaaatca atctaatcaa gtatcaccta ttacttctac
    21061 ttctttgata ggattgtcaa gtggattaac agagatacaa ggagatgtta ctagcaaatt
    21121 agttcctgcc agtcagtcga ttgcatcagg tgtaaacgca tatactacag gtgttgataa
    21181 agtttctcag ggcgcaagtc aactaagtga aaaaaatgcc accttgacag gtagtttgga
    21241 taaactagtt tcaggctcaa acaccttgac acaaaaatct tctagattga cagcaggagt
    21301 tggttaatta caatcaggat ctgggcaatt agcagacaaa tccagtcagt tactttcagg
    21361 tgcttctcca ttagagaata gagctaataa attggcagat ggatctggga aactagcaga
    21421 aggtggaaca aagttaactt ctggattgga agatttacag acaggacttg cttctttagg
    21481 acaaggacta ggtaatgcta gtgatcaact caaatcagta tcaacagaat ctaaaaatgc
    21541 agagattttg tcaaatccac tcaatctttc aaaaacagac aatgatcaag ttcctgtaaa
    21601 tggaatcgca atagctcctt atatgatatc agttgctctt tttgttgcag caatatcaac
    21661 aaatatgata tttgcgaaat tgccttcagg acgtcatcca gagagccgtt gggcttggtt
    21721 gaaatctcga gctgaaataa atggtattat agctgttttg gcaggaattt tggtatatgg
    21781 aggagttcag cttattggtt taactgctaa tcatgagatg agaatattta ttctcatcat
    21841 cctaacaagt ttagtattca tgtctatggt gaccacttta acaacgtgga atagccgtat
    21901 aggagctttt ttcttactta ttttgctttt actacagtta gcatcaagtg caggtactta
    21961 tccacttgct ttgacaaatg atttctttag atctattaat ccctggttac caatgagcta
    22021 ttcagtttcg ggattacgac aaacaatctc tatcaacaag tcattttcct agctgtcata
    22081 ctagctctat ttactggttt aggtatgcta gcctatcaac ataagaaaat ggaagaagat
    22141 taaaaaaatc gaccgattaa tgaactgcac cccaaaagtt agacagaaaa aatctaactt
    22201 ttgaggt
//
LOCUS       DAVBCA010000032        21993 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.032, whole genome shotgun sequence.
ACCESSION   DAVBCA010000032 DAVBCA010000000
VERSION     DAVBCA010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21993)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21993)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21993
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.032"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..217)
                     /gene="tnpB"
                     /locus_tag="VQU19_001204"
     CDS             complement(<1..217)
                     /gene="tnpB"
                     /locus_tag="VQU19_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HET2480456.1"
                     /translation="MTIHLSSLGQVYLVCGKTDMRQGIDSLAYLVKTHFELDPFSGQV
                     FLFCGGRKYRFKALYWDGQGFWLLYKRF"
     gene            complement(198..383)
                     /locus_tag="VQU19_001205"
     CDS             complement(198..383)
                     /locus_tag="VQU19_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480457.1"
                     /translation="MPQPIVPVEIPQSRPFDSKKRNDILLKIRIGKLEVSFFQSLNLE
                     MVEQLLDKVLLYDNSSI"
     gene            complement(687..2249)
                     /gene="guaA"
                     /locus_tag="VQU19_001206"
     CDS             complement(687..2249)
                     /gene="guaA"
                     /locus_tag="VQU19_001206"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HET2480458.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            2391..3089
                     /locus_tag="VQU19_001207"
     CDS             2391..3089
                     /locus_tag="VQU19_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET2480459.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(3132..4028)
                     /locus_tag="VQU19_001208"
     CDS             complement(3132..4028)
                     /locus_tag="VQU19_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HET2480460.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLLIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAIFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLISLKDLFLEK"
     gene            complement(4037..4972)
                     /locus_tag="VQU19_001209"
     CDS             complement(4037..4972)
                     /locus_tag="VQU19_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HET2480461.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(4969..5694)
                     /locus_tag="VQU19_001210"
     CDS             complement(4969..5694)
                     /locus_tag="VQU19_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HET2480462.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLGKDRNNVELWFEEV"
     gene            complement(5778..6413)
                     /locus_tag="VQU19_001211"
     CDS             complement(5778..6413)
                     /locus_tag="VQU19_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HET2480463.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEGEEYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKSLKDYLY"
     gene            complement(6415..7242)
                     /locus_tag="VQU19_001212"
     CDS             complement(6415..7242)
                     /locus_tag="VQU19_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET2480464.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALAHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(7264..7600)
                     /locus_tag="VQU19_001213"
                     /pseudo
     CDS             complement(7264..7600)
                     /locus_tag="VQU19_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
     gene            complement(7601..8317)
                     /locus_tag="VQU19_001214"
     CDS             complement(7601..8317)
                     /locus_tag="VQU19_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HET2480465.1"
                     /translation="MAHGDLLYHDGLFFSAKKEDGTYDFHENFEYVTPWLKQADLAIG
                     DFEGTINKDHYLAGYLLFNAPVEVMDAIKEAGYHVLDLAHNHILDSQIEGVISMADII
                     EKAGITPIGVYTHEPRDQAPLVIKEVNAIKVALLAYSYGFNGIEQYIFQEDYNRYLSD
                     LNEDKIKAEVERAEKEADITIIMPQMGVEYRLEPTEEQKALYHKMIDWGADIIFGGHP
                     HVVEPSKTVEKDGDKKLIIY"
     gene            8840..9451
                     /locus_tag="VQU19_001215"
     CDS             8840..9451
                     /locus_tag="VQU19_001215"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HET2480466.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRAIAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEGIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            9496..10224
                     /gene="rlmB"
                     /locus_tag="VQU19_001216"
     CDS             9496..10224
                     /gene="rlmB"
                     /locus_tag="VQU19_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HET2480467.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEMTEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFLNRL"
     gene            complement(10263..11174)
                     /gene="trxB"
                     /locus_tag="VQU19_001217"
     CDS             complement(10263..11174)
                     /gene="trxB"
                     /locus_tag="VQU19_001217"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HET2480468.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVKEIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDSHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(11240..11464)
                     /locus_tag="VQU19_001218"
     CDS             complement(11240..11464)
                     /locus_tag="VQU19_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HET2480469.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTARARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(11542..12285)
                     /locus_tag="VQU19_001219"
     CDS             complement(11542..12285)
                     /locus_tag="VQU19_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET2480470.1"
                     /translation="MIKISNLSKSFSGQTVLDHLNLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILLLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(12285..13085)
                     /locus_tag="VQU19_001220"
     CDS             complement(12285..13085)
                     /locus_tag="VQU19_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2480471.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(13243..13599)
                     /locus_tag="VQU19_001221"
     CDS             complement(13243..13599)
                     /locus_tag="VQU19_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HET2480472.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(13612..14124)
                     /locus_tag="VQU19_001222"
     CDS             complement(13612..14124)
                     /locus_tag="VQU19_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001170346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HET2480473.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDINK"
     gene            complement(14124..14618)
                     /locus_tag="VQU19_001223"
     CDS             complement(14124..14618)
                     /locus_tag="VQU19_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2480474.1"
                     /translation="MEIRLAFPNEVDAIMQVMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            14753..15199
                     /locus_tag="VQU19_001224"
     CDS             14753..15199
                     /locus_tag="VQU19_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HET2480475.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            15196..15843
                     /locus_tag="VQU19_001225"
     CDS             15196..15843
                     /locus_tag="VQU19_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HET2480476.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASALQYIAIVYYM"
     gene            complement(15864..16445)
                     /gene="pdxT"
                     /locus_tag="VQU19_001226"
     CDS             complement(15864..16445)
                     /gene="pdxT"
                     /locus_tag="VQU19_001226"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HET2480477.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(16446..17321)
                     /gene="pdxS"
                     /locus_tag="VQU19_001227"
     CDS             complement(16446..17321)
                     /gene="pdxS"
                     /locus_tag="VQU19_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HET2480478.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(17473..18852)
                     /locus_tag="VQU19_001228"
     CDS             complement(17473..18852)
                     /locus_tag="VQU19_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HET2480479.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKDKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            19147..20070
                     /locus_tag="VQU19_001229"
     CDS             19147..20070
                     /locus_tag="VQU19_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HET2480480.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGISPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            20130..20735
                     /locus_tag="VQU19_001230"
     CDS             20130..20735
                     /locus_tag="VQU19_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET2480481.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFADKAEIELVEIKTIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLTHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            20753..>21993
                     /locus_tag="VQU19_001231"
     CDS             20753..>21993
                     /locus_tag="VQU19_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET2480482.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRNFKFKFELEVLEIDEVPMF
                     NQDEKWDESFQLRFLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGGHGGDADATAGAS"
BASE COUNT         6572 a         4954 c         3992 g         6475 t
ORIGIN      
        1 caaagcgttt atatagtagc caaaatcctt gaccatccca gtaaagggct ttaaagcggt
       61 atttacgtcc accacaaaag agaaaaactt gacctgagaa aggatctaat tcaaagtggg
      121 ttttaaccag ataagccagt gaatcaatgc cttgcctcat atccgttttc ccacatacga
      181 gatagacctg ccctaggcta gatagatgaa ttgtcataga gcaacacctt atccaaaagc
      241 tgttctacca tttcgagatt gagagattga aaaaaactta cttcaagctt gccaatacga
      301 attttaagca gaatatcatt tctcttttta gaatcaaaag gacgagattg tggaatctct
      361 acaggaacaa taggttgtgg cattaaaata tcctccaata gttttacttt actaatagta
      421 tacaggagga actccatgaa tgatagatac cttgttatga cgcgattact atattagaaa
      481 gttggctctc taattaaatt aattctcatt atatatatca aaagaccgca gcttgaaaac
      541 tacggtctaa ttttttgtcc aaatgtaaac cacttggaac tattattcaa tttattcttt
      601 ttagtaaatg ttcccgtttt aatcccagtt acagttttta atcctctgta accgttgatt
      661 ttacaaagct tttaattttt ttgcgattat tcccactcaa ctgttgcagg tggtttactt
      721 gtaatatcgt agacgatacg gttaacatga tccacttcat ttacgatacg tactgagatt
      781 ttttgaagta cttcccatgg aattttggca aaatcagcag tcataccatc gatagaagtg
      841 atagcacgga ttgcaatcgt gtagtcatat gtacgaccgt cacccataac accgactgaa
      901 cgaacgcctg tgttaacagt gaagtattgc caaatatcgc ggtcaagtcc agctttagcg
      961 atttcttcac gaagaatagc gtctgattca cgaacggttt caagtttctc ttcagtgatt
     1021 tcacccatga cacggatagc aagtcctggt cctgggaatg gttggcgcca tacgatatgg
     1081 tctggcatac caagctctgt accaagagca cgaacttcat ccttgtaaag agtattgagt
     1141 ggttcaatca attcaaactg catatcttct ggaagaccac ccacgttgtg gtgtgacttg
     1201 atagtttgag ctgtatccgt accagactcg ataacatctg tatataaagt accttgagca
     1261 aggaatttca catctttgag cttgcttgct tcgtcatcga atacatagac aaactcgtta
     1321 ccgatgattt tacgtttttg ttcaggatca gaaacgccag caagtttgtc aaggaaacgt
     1381 ttagcagcgt ctgctttgac gatattcaaa ccaaacttac caccgagcat gtccataact
     1441 tgatcagctt cgcctttacg aagaagaccg tggtctacga agatacagat caattgatcg
     1501 ccaatcgctt tttggagaag aaccccaacg acagatgagt caacaccacc tgatagacca
     1561 agaaggacac gtttatcacc gacggtttca cgaatttttt tgatctgcat gtcaatgaaa
     1621 ttatccattg accagtcacc tttagcctta caaatgttaa gggcaaagtt acgaaggata
     1681 tcatttccgt atacagaatg acgaacttct gggtggaatt ggataccgta aatgtgttta
     1741 tctgggtttt cgatggctgc gtatgggcag tcagctgatg tacctgtacg aacaaagtca
     1801 gcaggaatct cagtaaccgc atcaccatgg ctcatcaaaa cagtctgttc atcaggtgtt
     1861 gattcaaaaa gcgctgatgg tgtgtgagtt agggttgatt gaccgtattc acgatttcca
     1921 gcatcacctg caggaacaac ttttcctcca agtttatggg tcaataactg cataccataa
     1981 cagattccca aaattggaat tccgagttcg aagatttctg ggtcaatatc aaatgaacca
     2041 tcttcatata cagaatttgg accacctgat agaataattc ctacaggatt gacttcacga
     2101 acttcagcag ctgaaatttt atggcttttt agttctgaaa aaacaccaat ctcacggata
     2161 cggcgtgaaa tcagctggtt gtactggcta ccatagtcca atacgatgat tttttctaca
     2221 tcttgcaaat cagttgaaat gttgctcatc tttttccttt ctcaaaagaa atatcttttc
     2281 tcaatattct atcacaaata agggcgaatt accaactaaa caaggcgaag tttgactttt
     2341 tctagtttat tggggtacaa tagagaaaag atagaaatga agtgaaaaat atgctacctg
     2401 cttatatgaa aatccatgat cagataaaaa aggatattga cgagcaccgt tgggctattg
     2461 gtgagaggct tcccagtgaa agagatttag ctgagcagtt tgcggtcagt cgcatgaccc
     2521 tccgccaagc cgtatctcta ttagtcgaag aaggcgtctt agagcgccgt gtaggaagcg
     2581 gcacctttgt ttccagtact cgagtacaag aaaagatgcg agggacaacc agttttactg
     2641 aaattgtcaa atcccaaggt aaagttccct ctagccagct catttcctac aaaaaaacca
     2701 ttcccaatga gcaagaagtt gccaagctag gaatttttcc aacggacaat attatccgaa
     2761 tggagcgggt ccgctatgcc gaccaagttc ccctagttta tgaagttgct tctattcctg
     2821 aaaaattcat taaggacttt aaaaaagaag aaatcacaag tcatttcttc caaaccttgc
     2881 aaaaacatgg ctatcgtatc ggcaaatctc aacagaccat ctatgctcgc cttgctaaag
     2941 aaaagattgc ccactatttg gaagttgaaa aaggacatgc tattcttgga ttgacccagg
     3001 tttcctacct agaagatggt actgcttttg aatacgtaaa aagtcaatat gtaggcgaac
     3061 gctttgaatt ttatcttgaa aataattaga ttaccacgca aaaactctct gtcacggaca
     3121 aagagtcttt tttatttttc taagaataaa tctttcaaag aaatcaaagt tacagcaaac
     3181 aatatcattg ccataccaag aaaatcaatg ggataaaatt gttcattcat tattaagaag
     3241 gcaaagaaaa tcgccgatat tggctcaatt gaagccaaca agcttgactt gaccggtcct
     3301 atcagactgg ctcctttaag gaaagctgta taggcaaaga cagtcccgat aaggataatg
     3361 cctgcaaacg caaggagaaa atcaagacta gtcgggatat cggcctgtag aacccctgta
     3421 aaaggaaggg cgaccaaacc tgctatgacc attcccacac caatgagcaa gctgctcccc
     3481 cactttttaa tcaaggctat gggtaaaatg atatacagag cataagtcaa ggcagaaaag
     3541 agaccccaga acagaccagc aggtgtcatg gataactggt ccaactgccc atgtgttgcg
     3601 atcaggaagg ttcctccgat ggcgaatatg atggaaacta tctctcccag tgtcggtgcc
     3661 accctatcct tgatacagct ataaattaaa attccgacag gacaaacata ctgaagcacc
     3721 gtcgctgttc ccgcattggt ctcctgaata gcagacagat aggcgaattg gttgagaaaa
     3781 agaccaatca gagcaaaaat aagaagagac agcaaactct ttctatcctt taaaaagacc
     3841 agtattttat cctttgcagt agcataagcc aagagcatga gaattccacc agcgattaaa
     3901 agacgcaagt tggtcaagac cagagccgaa attccgtgtg ccattaggta ttggccactc
     3961 gttcctgaca acccccaagc aataccagcc acaactgtta gtaaagtccc ttttaaacta
     4021 tttgacatgt ctctccttac tcttctttgc gaatcaagtt catcacttga ttgcggtcta
     4081 atatccattg agctctctcg tccttttcat aggtacgatt cgataggaaa atagtggctt
     4141 cttgcttctg acgattccac atgataaagg tacctgtata gcccgtatgg tctagccaat
     4201 ctccttccaa attccatgct aaagaacgtt ccttgtcatc caaaggagaa aaattttgat
     4261 ttaagtctct tgcaaaatca tctgctaaat agtgttctaa aaagatttgt aaatccttta
     4321 tagtcgaaaa taaaccagca ctcccagcat gtctacccag gagacgagcc ttgggatcat
     4381 gcactatgcc tgcctctaca cctctaactg ttggaacagc aagctcaact ggcccaaact
     4441 tggtttccgt cattccccaa ggtttccaga cttgatcctt taaaatcaca tccaaatctt
     4501 gattaaaaat tctttccaaa ataaagccca acagcaaaaa atggacatcc gaataaagaa
     4561 aggctggctg acttcgtctg ttgagatgaa acatcgcttc ctttaattca ggggctgtta
     4621 aaagatcacg attaggaata aaaggatcaa ggtctgttgc atgagtcaag agctggcgaa
     4681 tagtgatgtc tggataatca ctctcaggta aaaaatctat taccagtcta tcaatatcta
     4741 attgacctat ttcccacaag aaggtacaaa ctgtgccaac cccaacaacc ttgctgacac
     4801 tagctagatc ataaactagt cctgcctcag tctgcaagcc atgctctggg tcactctggc
     4861 ctaaatagaa ctctgtccat tgattgtcct taaaatacgc aaaagaggct ccgggataaa
     4921 ttcctgcctc gatttgttct tctatttttt taataatctt ggtccacttc atacttcttc
     4981 aaaccacaat tcaacattat ttctatcttt accaaggaag aatttttcag acttaggaat
     5041 aaaatattca gtagactcaa acttctggcg aagacttgct atgtctaatt cattgaccaa
     5101 gaacttgagc atagataagt cccaggtaac cgtattgtcc acagtcaaat cctgcccctg
     5161 agctggaata aaatcaaggg atgccccaat ttcagatgat tccaagaaac tttcgatatc
     5221 agttgggaga tgtaattcca tagaaatctc aaatttactt aaagaaattg atgccaaatc
     5281 tgtttgaaat tcaggctttt ctcctacttc tactagactt gctctgtcat cttccgcatg
     5341 aatcaaaatc aaatcatctt ctggtgagaa aatttcaaaa gcgtagccat tttgaccttt
     5401 atataatcga tgaatcgaat ctgttttaga taagattcct tcaatttcta agggattttc
     5461 caccttgaca atcaatctag ctagtttttt tcttccctct accttacgag tacgcatact
     5521 gggagcttct tctaaaacca gcttttcaag acccgtttgg tcacctagtg acagaaaggc
     5581 cgattcttct aacaaggcct tcattccaag ggtttcaata taaaatgttt catttaattt
     5641 tctattatta gcttttaaag taggaataat ccgtacaatc tgatttacat tcataaattc
     5701 ctccgtcact ttttatttta aaggatttta gaatttttta caagatatta tgctcaaatt
     5761 taacattatt tagctattta gtaaagatag tctttcaagg attttgacaa agcctgataa
     5821 ccagcaatac tgaggtgcag tccatcagtt gtatattctt ttttgagttg gcctgcttgg
     5881 tctgtcaaac aatcaaatac tggcacaaat tccacctgca tataggcaga tgcaagctct
     5941 tgataggctt gattccagtt ctgaattttt tcattcgagc ggatatagac tgcctgctgg
     6001 tactcctctc cctcattgac aggcaaaatg gaaagcaatt taatctctgt caatggataa
     6061 tcgcgagcaa cggattgaat gatagcttcg agattattga gagcctcatt cacaggaaca
     6121 tcctttccga tatcatttgt cccaatcaga agaaaaattt tatctactgc tccaccatat
     6181 agatgagcat caagattctc tagtaacagt cctgtctgat agccacgaat tcctcgattg
     6241 acaatcgtct ttgaagtccc aaatagctcc tgtagaggat aatactcgac aatggaatcc
     6301 ccaataaaaa gaatgtttgg ttctacaaca gaaatgtgat ttaggtgacg atacttagtt
     6361 tgaatttttt cttgttcctt taggagccaa ttttctaata actgtactgc cacttcattc
     6421 tcctttttct aaccagtttt ccaagacttg ataaactcct ccttggctgt tggctggtgc
     6481 tagagcagtc gccacagctt tggctttctc atcagcattt tccatcgcat aggcaattcc
     6541 agccatttca agcatttcaa catcattttc actatcacca aaagccatga tttcttggga
     6601 tttcaagtcc cagcgcttga gtaattcctc caagccccat gctttatgaa tcccagcttg
     6661 gaggatatca atgcaaccat agccactgga tacagctcgg acacggccat caaagagagc
     6721 attgatttct tccaaaaccg aactcaaacg ttcctcacca acaaccatgc tcatcttgag
     6781 cacaccacca aagaggtcag atgttaattc atccacaaat tgcatccgtt ggtagaattt
     6841 ttcaatcatt tctggagtca taaaactttc aagatctgta aaaatcgtac cttccttgac
     6901 aaaatcaccc ttcatccccg ttacaacaaa ctggtcctga cacgctcgac ccttgaaatg
     6961 agccaaagcc ttgttgacaa tggcgtcatc ccatgtctga gcctgaatca attcattgtt
     7021 ttcaaaaata cgagcgccat tagcaacaac cagaaccact cgatccacca agggactcag
     7081 tagttgtctc atgcggtgaa tttcattgcc cgtcgcaatg acaaaacgaa tgcccctttg
     7141 atccaactga tctaaaatct tttccaatcg tgggagatca agctgacccc tagcatccag
     7201 caaggtccca tccatatctg tcgcaattac cttaatcatc atttactttc ctctggattc
     7261 aagctaatac cacttcaatc ccacatgttc attcatttct ttataggctg tatcaattcg
     7321 ttccttagtc gcttcatcta actggtcacg atgactgcca cccctctata aaatcttcca
     7381 aaatataagt ttggtaatga tacaagggat atccttctgg tgaaaaggtt ccctttggtg
     7441 ttcgattgac ccaagtagga tgagctttag ctgttccgat agttgttttt ccatccttct
     7501 tcttgatggt gacatccatg agaacaccac gttcagtcca cttagcattc tcttcatctc
     7561 ccatagattc aatccgttga ttggaaatga agttccccat ttaatagata atgagtttct
     7621 tatctccatc tttttcaacc gttttagatg gttcaacaac gtgaggatgc cctccaaaga
     7681 taatatccgc tccccaatcg atcatcttgt gataaagagc tttttgttct tcagttggtt
     7741 ccaatcgata ctcaacaccc atctgaggca tgataatggt gatatctgct tccttctctg
     7801 cccgttcgac ttcagccttt atcttatctt cgtttaaatc tgaaagataa cgattatagt
     7861 cttcctgaaa aatatactgc tcaattccat tgaaaccata ggaataggct aacaatgcaa
     7921 ccttgatagc attcacttcc ttaatgacca gcggagcctg atcacgtggt tcgtgcgtat
     7981 aaactccgat tggagtgatt ccagctttct caataatatc ggccattgaa ataactccct
     8041 caatttgcga atccaaaata tgattatgag ctaaatccag cacatgataa cctgcttcct
     8101 taatagcatc cataacttca acaggagcat taaagagaag ataacccgct aaataatgat
     8161 ccttattaat ggttccttca aaatcaccaa tagctaaatc tgcttgcttg agccaaggag
     8221 tcacatactc aaaattttca tgaaagtcat aggtaccgtc ttctttttta gctgaaaaga
     8281 aaagtccatc gtggtagagc aaatccccgt gggccataat tctggcagtt ttttcctctt
     8341 cctactcctg agacttttgc ttagtcccct cttgagaaat agtatctcgt ttttgactag
     8401 tcaagggatt ccttggaagc tttcaaacaa caagaccaag cccattgata aaccaactgc
     8461 tagcaagagt atcgccacaa atcccttatt gctccacttg cgataactcc taaaaagttt
     8521 accaagccct tcataaaacg aaaagctaaa ccaccctgat ttcgattttg tcttctttgt
     8581 atcttcattc tccctacttt cttatgcaag ccttttcttt ttattatatc acagataagt
     8641 atttctttca caattgaatt gaacttccca tctattttct ataaatccta aatgccataa
     8701 tgctttcaat tcttgtcatt ttgtgatatc atgtagaggt aatgaaagga aatgaactaa
     8761 tccacagtgg cttattccaa gtataccact tgggctttgg cagtagttaa ctgcactaaa
     8821 cataatataa ggagagaaaa tgtctgcaat agaacgtatt acaaaagctg ctcacttaat
     8881 tgatatgaac gatattatcc gtgaagggaa tcctactcta cgcgcgattg ctgaggaagt
     8941 cactttcccc ctatctgacc aggaaatcat cctaggcgaa aagatgatgc aattccttaa
     9001 acattcccaa gatcctgtca tggctgaaaa aatgggactc cgcggtggtg ttggactggc
     9061 tgctccccag ttagatatct caaaacgcat tatcgctgtt ttggtaccta atattgttga
     9121 agaaggcgaa actccacagg aagcctacga tttggaaggc attatgtaca atccaaaaat
     9181 cgtctctcac tctgttcaag atgctgctct tggcgaagga gaaggttgcc tgtctgttga
     9241 ccgtaacgtg cctggctatg ttgttcgcca tgcccgcgtt actgttgact actttgacaa
     9301 agatggagaa aaacaccgta tcaaactcaa aggctacaac tccattgttg ttcagcatga
     9361 aattgaccac attaacggta tcatgtttta cgatcgcatc aatgaaaaag acccatttgc
     9421 agttaaagat ggtttactga ttcttgaata aagaaaatcc cgttgcaaga cggggttttg
     9481 tgttataata gaggcatgaa aacaaatgat attgtctatg gtgtccacgc cgttaccgaa
     9541 gccctccttg caaatacagg aaacaaactc tacctccaag aagatctccg aggtaagaat
     9601 gttgagaaag tcaaggaact agctacagaa aagaaggtgt ccatttcttg gacatcaaaa
     9661 aaatctctct ctgagatgac tgaaggtgct gttcatcaag gttttgttct acgagtgtct
     9721 gaatttgcct atagcgagct agattacatc cttgcaaaaa cacgccaaga agaaaatcca
     9781 cttctattga ttctagatgg tctaaccgat ccccataatc tgggttctat cttgcgaaca
     9841 gccgatgcga ccaatgtttc aggtgtcatc attcccaagc accgtgctgt cggagtaact
     9901 cctgtcgttg ccaaaacagc cacaggtgct attgaacacg ttccaattgc ccgagtgaca
     9961 aacctcagtc aaaccttaga taaactcaag gatgaaggct tctggacctt tggaacggat
    10021 atgaacggta ctccttgcca caagtggaat acaaaaggga aaatcgccct catcatcgga
    10081 aatgaaggaa aaggcatctc tagcaacatc aaaaaacagg tcgatgaaat gattaccatt
    10141 ccgatgaatg gacatgttca aagcctcaat gccagtgttg ctgcagccat tctcatgtac
    10201 gaagtttttc taaatagact ataaaaaagt ttccagtcat ctgattggaa acttttttat
    10261 gattaactat gttctgtgat aaacttgtag gcttcttgac cagcgatagc tccatctcca
    10321 actgctgttg ttacttggcg aaggtctttc aagcgaacat ctccaactgc aaagataccg
    10381 tcgactgcag tcttcatgtg gctatctgtc acaatccagc ctgcctgatc ttggatattc
    10441 aattctttaa caaaatcgct aagagggtcc aaaccaacat agataaagac accaccgaag
    10501 gcttgctctg tcacttgacc tgttttcaca ttttcaaaaa cgacagattc tactctgttt
    10561 tcacccttga tttccttcac tacagaatcc cagataaagc tgattttttc attcgcaaag
    10621 gcgcgatctt gtaaaacctt ttgggcacga agttggtcac gacggtgaac aatggtaaca
    10681 gtcttagcaa aacgagtcaa gaagagggct tcttcaacag ctgaatctcc accaccaact
    10741 accaataaat cttggtcacg gaagaaagca ccatcacaca cagcacagta agaaacacca
    10801 cgactgttca gttcttcttc tccaggcact cccaaaggac ggtgtttaga accagttgct
    10861 acgataactg tacgtgtttc atatgtttgg tcatcagtca tcactttctt aaaatcacca
    10921 tggtcttcga cattttcaac ataaccataa atgtgctcaa caccaagatt ttcaagtggt
    10981 tcaaacatct tttcagccaa ttcaggtcca ctaatattag cgtatcctgg gtaattttcg
    11041 atatcagatg tattattcat ctgaccacct ggcagaccac cttcaatcaa agctactttt
    11101 agattgcttc gagcagcata caaggccgca gtcatccctg caggtccagc accgataata
    11161 atagtatcgt acatatagat tccttctttc ttgttgtaac tatctttatt ctaactcttt
    11221 cttgtcaatc acgcaaggat tatgccttga aaacaagaat taaactcata accgcaaagg
    11281 ataatactgg gacaaccaag actccaatca taatcatatc atagagatgg gcttggcgag
    11341 ccctggctgt cttatcaact cccgacatgg ctctcagacc aatccaaatc cctaaaaaaa
    11401 tcagaacaag gatggtggtc aagatcaaac tctcgaaata taaagaaaat agttgcagta
    11461 gcatgatttc tctcatttct atctttttta aagagtaaac tcagctagtc caactaactg
    11521 agttttcctt tatctattat atcaaatata agtccgtttg taactagcga agaattcttt
    11581 tgtccgctct tctttagggg tgtggataat ctcatccgga gttccagact cgatgatttt
    11641 ccccttatct aataagagaa ttttatccgc aacttgggct acaaaggaca tgtcatgact
    11701 gaccaaaatc atggtctgac ctgacttagc agcatctgca atagactttt ctacttcacc
    11761 gaccaattct gggtcaaggg ctgaagttgg ttcgtctaag agcaaaacat ctggtttcat
    11821 agcaagcgca cgcgctaggg caacccgttg cttctgtcca cctgataaat ggcgaggata
    11881 atggttttca cggtccgaaa gcccaacctt agccaactct tccttggcaa tcttagtcgc
    11941 ttcttggtca gataatttct tgacaacaac caagccttct ttcacattat caagtgctgt
    12001 tcgacgttca aataaattaa actgttggaa aaccatagac aacttacggc gtagggcaag
    12061 gatttcttct tgagtgattt tagaaaaatc aactgaaaaa ccatcaatct gaatagagcc
    12121 actgtcaggt gtttcaagat aattgagact gcgaagaaag gttgattttc cagctcctga
    12181 agaaccaatc aaggctacaa cttccccttt ttgaatatcc aagttcagat gatccaagac
    12241 agtctgtcct gaaaaggatt tgcttaaatt cgaaatctta atcattaacg aaggtctcct
    12301 ttcacatctg tttgcactgt atcaggtgca gaaatagcca tttttctctc gatgaaacga
    12361 ccgaggcttt caattccgat attgactacc caataaacaa gggcaacaga gatgaagcgt
    12421 tcaaaatagc gataatcagc tccacctaga atctgagctt gggcaaagac ttccacaaca
    12481 cccgcactaa aagctagaga tgttcccttg gtcaaaccga tgagggaatt aatcaaggtt
    12541 ggagtagcta ccaccgctgc attaggaata atcactcgtc gataaacttg cgctcgggtc
    12601 atacccagac tgcgcgccgc ctcaatctca ccaggattaa ctgagagaat ggctgcacga
    12661 atggtttcac tagcataagc tgcctcatta aaggcaaaag cgacaatcgc aaaagctgca
    12721 gctggaatcg cattgatatt gagaccagtt ccccattgct gattgagggc tttcaaagcc
    12781 aaagggattc cgtagtaggt caacatgagt tgcaccaaaa tcggtgtccc ttttaagaaa
    12841 ctaacaaaga aggcctgcaa gggatataaa atcttgacac gattgatctt cacaatggca
    12901 aaaagaagcg ccaaaaccaa gccaaaaagg gcaccaccaa ttgtcaacat aattgttgtt
    12961 ggaagttgtt ggacaattct agggattcca tcaaagaccg aacgtaggct aaacagcttg
    13021 ccatccggaa tcaattgcat caagttttgg taccaatctg atgctaaaat cgttgtaaca
    13081 ttcataaaaa catcctcttc tgataatgat tcattctacc atgcttctgc cgtcaatgaa
    13141 attatttgct acggtcagat acagactttg tctacctact agtttatcat actttgaaac
    13201 agggaagtta tatattttat ctatcaaaga gatagataaa aactatttca gtcccagttc
    13261 ttcataagat tttcgataac cgatttgctt aacagttcca ttttctacta aaatgggccg
    13321 ttttaacaac ataccgtcac ttgctagcaa ctcagccgct tcttggtttg acaaacttcc
    13381 taccttatct tttagcccta attcacggta tttgatacca ctggtgttga aaaattgctt
    13441 caattcaaat cctgaggttt ctagccaatt caaaatgact tcttggctag gtgtttcttc
    13501 cacgatatgg acggctttat agtccacacc taattgattt aattcttgtt ttgctttttt
    13561 acaagttgaa catttggggt attcgataaa ttctaacatg tgcttctcct tctatttgtt
    13621 tatatcttta aaatctacgc cttcatgctc caagagccaa gctttctttt ccactcctgc
    13681 agcatagcct gtcagacgct tgcctgctcc caacacacga tgacaaggta ctaggataga
    13741 ccaaggattg cgtcccactg ctccaccaat tgcttgagca gaagccactt gcaggtcttg
    13801 agcaatttgt ccataggtca ctgtctgacc ataaggaatg ccctgtaaat agtcccaaac
    13861 tctcttttca aaattcgttc cgattggcgc caagagcaag ttggataaat cctgaggctt
    13921 gcctttaaag taatcatcta agcaagcaat aactgggtct aaaataggat gactaacaac
    13981 ttcttctatc gtttcatctc ctagtcccct ctcaaaatgc ttctgctcct gaacccaaat
    14041 tccatacaaa taatggtcat cagctacaag tgatagaata ccaattggtg aggagtagag
    14101 tatttttaca tacttctttt gcattatttc tttaattttt gataggccaa gcgttcgcca
    14161 tctactggca ccttaccaac ttgtttaaaa ccaagttttt caaaaatatg ttgcataacc
    14221 ttgttttcag catgcgtatc tgagcgaaaa tcaagataat caaaaccttc aatcaagccc
    14281 tctaagaagg tttgagcaac tccttttccc tgcacatctg ctgccacagc aatacggtga
    14341 aagactagat actctgactc tccagcttgc cagtttccct cataaatagc ttcataggcc
    14401 tcctctggac tcttggtcac agcagcatag gctagcagtt ctccctcttc caaggctacg
    14461 taggcttgcc ctgagatgat atcatcgata ataacatctg catttggata gccattttgc
    14521 cactggtcac taccagcatc tgctaaacat tttttggcat cctccatcac ctgcatgatg
    14581 gcatctactt catttggaaa agctaaacga atttccatct tttttcctca tttctgacta
    14641 gtttctccca tcatagcata atttaagtat ttctacaagc agttaaaact tgactttgtg
    14701 tttttgttat tttataatct agttatcaaa actatataaa aaggagttga aaatgaaaac
    14761 taccttttcc tacccaaaat gggcagaaat tccaaacatt gacctctatc tggaccaggt
    14821 tttgctctat gtcaatcagg tctgcgcccc tatctctcct aataaagaca agggcctaac
    14881 agcatctatg gtcaacaatt atgtgaaaaa tggttacctg acaaagcctg acaaaaaaaa
    14941 ataccaacgc caacagattg cccgtttgat tgctatcaca accctcaagt ctgtattttc
    15001 tattcaagaa atagcccaga cacttaatac tctacaaact caagcaagtt cagaccaact
    15061 ctacgatgct tttgtggact acatgaacca aggaattgac ccagctaacc ctattatcca
    15121 aaccagctgc caaaccgtca aactctatca tcaaactcta gacttaatcg atcatactca
    15181 agaggaggta atccaatgaa cactagtctt aaactcagca aacaactcag ttttggagag
    15241 gagattgcta atagcgtgac ccatgctgtg ggtgcagtca tcatgcttat cttgctgcct
    15301 atttcatcca tctatagtta tgaagcacac ggatttttat cctctatcgg cgtttccatt
    15361 ttcgtcatca gtctctttct catgttccta tcatccacca tttatcactc tatggcctat
    15421 ggttcgaccc acaaatatgt tttgcgaatc attgaccatt ctatgattta cgttgccatt
    15481 gccggctcat acacgcccgt tgtcttgacc ttgatgaata actggtttgg ctatctgatt
    15541 attgtcatcc aatggggaac gaccatcttt ggtattctct ataaaatctt tgctaaaaag
    15601 gtcaatgaga aatttagcct tgctctttac ctgattatgg gctggttggt tctggctatc
    15661 attcctgcca ttatcagtca aacgacaccc gttttctgga gtctcatggt aactggcgga
    15721 ctctgttata cagttggagc tggattttat gccaagaaaa aaccttattt ccacatgatt
    15781 tggcatctct ttatcctagc tgcgtccgca cttcaataca tcgctattgt ttattacatg
    15841 taaaaaagtt gagaaattca atctcaactt ttttctttac acatattgat aaagtactgg
    15901 tgcaagcgca catcatcagt caattctgga tgaaaagaac ttaccaacat atttttttct
    15961 tgggctgcaa caatttgatt gttcactgtt gctagaattt ctacaccctc accaacacta
    16021 ctgataatcg gaccacggat aaaggtcatt ggaatcttgc caactccctt acattctgct
    16081 tccgtgtaga aacttcctaa ttggcgccca taagcattac gctcgaccac catatccata
    16141 gttcctagat gactctcttt ctgagaagtg atttccttag ccagcaaaat taagcccgca
    16201 caggtcccaa acactggtaa gccagataga atggcttctc ggatgggaag tagcatgttc
    16261 tggtcacgta agagcttgcc catggttgta gactcaccac caggcaaaat caaacccgac
    16321 aagtcactct gatcttgctg aaaatcatct agatttctga gttctacact ctcgacacct
    16381 aattgatcta gcacttttgc atgttctgca aaggcccctt gcaaggccaa tattccaatt
    16441 ttcatctatt ttcctcgttc agccatgaga atttggattt cattttcatt aataccaacc
    16501 atggcttctc ctaaatcttc agagatttga gctaggattt gaggattacg gaagttagtc
    16561 acagccttaa caatggcact cgctcgttta acaggatctc ctgacttgaa aatacctgaa
    16621 ccgacaaaga ccccctctgc ccctaattgc atcattaacg cagcatctgc tggcgttgca
    16681 acacctccag cagcgaaatt tacaactggc aattttccat gttcatgaac atattggacc
    16741 aattctacag ggacttgcaa atccttggca gcaacataaa gctcgtcctc acgtaagttt
    16801 tgaatgcggc gaatttcctg attcatcata cgcatatgac gaacagcttg gacgatatcc
    16861 cctgtccctg gttctccttt ggtacgaatc atggaagcac cttcagcgat acgacgcaag
    16921 gcttcaccca aatccttagc accacagaca aaaggaactt ggaattcttt cttgtccaca
    16981 tggaaacggt catcagctgg agatagaact tcactctcgt cgatataatc aatttcaata
    17041 gcctctaaaa tctgagcttc aacaaaatgc ccgattctga ccttagccat tactggaata
    17101 ctaaccgctt cttggatttc cttaatcatc tttgggtcgc tcatgcggga aactcctcca
    17161 gctgcacgaa tatcagccgg aattcgttcc aaggccatca cagctgccgc accagcagct
    17221 tctgcgatac gagcctgttc aggattctgc acatccataa taacaccacc cttgagcatc
    17281 tgtgccaagt ttttatttag ttcataacga ttttcagtca tttgttttat cctcatcatt
    17341 tgtattggta gctacctttt cattttaagt cagaacagaa tgaagcacaa gataaaaaaa
    17401 ctataattgt atggggacag attggctaaa aactatctga ccttaactta aggccagata
    17461 gctcattcat ttttattttt cagccgtaag ggcagccatt gtgatgtagt tgtatggttt
    17521 attgaagtgt ggcaagaaga agaggtctgt caatgccaat ttatcaattg tcacatgctc
    17581 ttggatagca agtgagaaca tgtggattcc catgctaatt gcaatatcat gtgaaaccat
    17641 ttgggcacca agaatttcac ggctatcttt gtcaaagaca atcttaattg ctacttcatg
    17701 gttgtcatgt ttcatgaatt ctggtttttg aagatcgtta aagcctgttt cagttgcgtt
    17761 gtaaccagca gctttcgctt tttcaagagt caaaccagtt gaaaccatgt gaagaccgta
    17821 gattgagata ccatttgaac cttgaacacc gattccttcc aattcatgtc cacaagcgtt
    17881 gtaggcacca acgataccag tgcgaacagc atttgaagca agagcgatat agcttgtatc
    17941 tttacgagca ttgtcataaa cagtcgcaca gtcaccaaca gcgtaaacgc ctgggataga
    18001 tgtttcttgt ttcttgtcta caaggaaggc accgttgcgg aagagttcga tcttaccatc
    18061 agcaagggct gtgtttggac ggaaaccaac tgcaaggata accatatcca cgtcaaagct
    18121 ttctttgtca gtaatcaagc gttcaacttt accatcacct tcgattgctt taacagtttg
    18181 acctagagcc aagcggatgt tgtgatcttc caagttcttc gccatcattt gtgtgaagtc
    18241 tttgtcatag taaccgttca agacagtatc aacgatatca acaaggacaa cttcttttcc
    18301 aagacgttca aaggcttcag caagttcaac accgatgtaa ccaccaccaa caacggcgat
    18361 acggtcgaga tgttggctct tgtcagaaag tttattgata acttcttcag cattttggta
    18421 caatttcacg aattgtacgt tttcaagagt tgctttaaat tcgcggtttc ctttaacaat
    18481 ttcaacacct tcgattggtg gcaagattgg tgtagaacct gtagcgaaaa tcaatttctc
    18541 gtatgattct ttgtgttctt ttccttcaac ttctgctgta accactttgt tatcatagtc
    18601 gattgaaaga actggtgaat tcatataaac cttagcacct ttagcttcta atttgtcttt
    18661 atcagaatag aacaagcctt cagcaccgtc aatttgttca ccaatccaaa gagccattcc
    18721 acatcctagg aaagagatgt tagagttttg gtcaaataca acaatttcgt tctcatttcc
    18781 aaaattatcc aacatggtat tgatacatgc tgtaccagcg tggttagcac cgactacaac
    18841 gattttactc ataaaaaatt tcctgccttc attctaaatt tactttacta gtataccatt
    18901 taccgttagc gtttacaagg gggggactat tatttcagca ttttttatca aaaataattc
    18961 cccatttatc ctgttttcaa gcctcatgaa ttttatgagc atatttcttg actttttcca
    19021 aattttgttt gtgaaaattc taactttatg gtattataat aacatgaaaa taaaatgtaa
    19081 gggcttcaat ttagatgatt atttgatatt gcaacttatt ttctataaga gaaaggagtt
    19141 ggtagcttga ctcttcgttc acattctgaa cggctaatgg ggactactat cactatttca
    19201 ttagtggatg agcaagccga tatctttctc caaaaatcct ttgacttgct caaagagctt
    19261 gaataccgct tcaacgccaa tagtcaagaa tctgagttga tggaaatcaa ttatcaagca
    19321 ggaatatccc ccgtcacagt tcatccagac ctgtttgagc tgatttcact tgggttagag
    19381 catagcctag cgctctctag ccacctcaat atcagcattg gtcccttaat tcaaacctgg
    19441 cgtatcggtt tttcagatgc caaggtcgcc cagcctcaag aaattgaatc ggtgctgcct
    19501 ctaatcaatc ctcatggtat cgagttagat tcttctactt ctactgtgtt tttaaaacag
    19561 aaaggaatga agatcgatct aggttgttta gccaaaggat acagtgcgga taaggttgcc
    19621 caatttctta ggaaagaggg ggtgacttct gccttgatca atctgggagg gaatatcctg
    19681 accattggaa aaaatcaggc aagaggggat aacccatggc aaatcgggat tcaagaccca
    19741 gccaatccta ggggaaatca tttaatgacc atccctgttg tcaataaatc tgtcgtgact
    19801 tcaggcattt atgaacgtca cctgaccgtc gatggacaag attaccatca catttttgac
    19861 agtcaaacag gatatcctgt tgaaacggaa ctagcgagtc taacaatcat ctctgataaa
    19921 tcagtcgatg gcgaaatctg gacgactcga ctctttggag aaagacctgc ttctatcctc
    19981 tggcaagtcg aaagtttgga gggcatcgaa gtcatcctca tcgataaaga aggccaccta
    20041 agctgttctt caggaattcc tactctatag agacaactgt ttcaatggaa ttttaaaatt
    20101 gtattatgta aaaagagaaa ggaaatatca tgttaaaact tattgctatt gttggaacaa
    20161 attcaaaacg ttctacaaac cgtcaattgc ttcaatacat gcaaaaacac tttgctgaca
    20221 aagctgaaat tgaacttgtt gaaatcaaga ccattcctgt cttcaacaaa ccagctgaca
    20281 agcaagtacc tgctgaaata ttggaaattg ctgctaaaat cgaagaggca gatggcgtta
    20341 ttatcggtac tcctgagtat gatcactcta ttccagctgt tttgatgagc gctcttgctt
    20401 ggttgtctta tggtatttac ccacttttga acaaaccaat catgattaca ggtgcttctt
    20461 acggtacgct tggttcatct cgtgcccaat tgcaacttcg tcaaatcttg aatgctcctg
    20521 aaatcaaggc aaatgttctt ccagatgaat tcttgctcac acactctctt caagcattta
    20581 acccaagtgg cgacttggtt gaccttgatg ttatcaagaa attggatgcc atctttgatg
    20641 acttccgtat cttcgtgaag attactgaga aattgcgcaa tgcgcaagaa ttgcttcgca
    20701 aagatgctga agactttgac tgggaaaatt tgtaagatag gagaccgaaa gaatgaaatt
    20761 tgttggactt gttggatcaa actacgatca atcatataac cgcaaactct tggaatttat
    20821 ccgtcgcaat ttcaaattca aatttgaatt agaagtactt gaaatcgacg aagttccaat
    20881 gtttaaccaa gacgaaaaat gggacgaaag cttccaattg cgtttcttgt ataacaagat
    20941 tacacgtgct gatggtgtca ttatcgccac tcctgagcac aaccacacta tctcagcttc
    21001 actcaaatct gtacttgaat ggctttcata cgaagttcat ccatttgaaa acaagcctgt
    21061 tatgattgtg ggtgcatcat actatgacca aggaacatca cgtgctcaag ttcaccttcg
    21121 taaaatcctt gatgctccag gtgttaatgc ctacacgctt ccaggtaacg aattccttct
    21181 tggtaaagct aaggaagctt ttgataacaa cggaaatatc accaacgaag gcactgttaa
    21241 attccttgaa acttgcttag ataactttgt taaatacgta ggagtcgttt cgaaattgaa
    21301 aaaaccaaaa ccaatcgaat cagaagactt ggattgtgga aaaccaatcg ctacaaccat
    21361 cacagaagtt gaccctgacg atccagaatg ggtagaaaaa gttgcagcaa tcactggtgc
    21421 tgtttctggt gatacctatg tcaaattgga ccacggtatc ctaacagtta accaaattga
    21481 tatgttcttg aaagctatgc catttgaatt gacatacgct gacgacaaca accaattcct
    21541 ctactacaac aacgctcacc aagatccaga cactatgttc gctaaacgtg taccacctca
    21601 atcaggtagc cgtatgtcga ctgttcatgg ttctcttcca ccagcacgta tgaagaacgt
    21661 agagtgggtt atcggaacac ttcgcaacgg aaaccaagaa tacgtccgta cgatcgttcc
    21721 aggttctcct gcaggtgtta tcaacactca caactaccaa gcaatgtact atcctgatgg
    21781 atcatacgct ggtatcaatg aaatcgtctt taacttccaa ccatggcttg actggtacct
    21841 aaaagagact ggtcaacgtt tggtgggtgg tagcggacca tttgctcctg ctgccggagg
    21901 tcatggagac gccgatgcta cttctggcgc ttctgattca ggggatgctg gaggccacgg
    21961 tggtgacgca gacgctacag ccggtgcaag tta
//
LOCUS       DAVBCA010000033        21414 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.033, whole genome shotgun sequence.
ACCESSION   DAVBCA010000033 DAVBCA010000000
VERSION     DAVBCA010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21414)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21414)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21414
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.033"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            66..287
                     /locus_tag="VQU19_001232"
     CDS             66..287
                     /locus_tag="VQU19_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2480483.1"
                     /translation="MYRRLRDLREDHDLTQKQIAKILSFTNSAYAKIERGEHTLTADV
                     LVTLSNFYDVSTDYLLELTDFPDKIRFRK"
     gene            804..1043
                     /locus_tag="VQU19_001233"
                     /pseudo
     CDS             804..1043
                     /locus_tag="VQU19_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558195.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            1187..2416
                     /locus_tag="VQU19_001234"
     CDS             1187..2416
                     /locus_tag="VQU19_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HET2480484.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSAASVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            2436..5132
                     /gene="ppc"
                     /locus_tag="VQU19_001235"
     CDS             2436..5132
                     /gene="ppc"
                     /locus_tag="VQU19_001235"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HET2480485.1"
                     /translation="MSLQKLENSSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATNLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYEIILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     misc_binding    5215..5432
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5545..6549
                     /locus_tag="VQU19_001236"
     CDS             5545..6549
                     /locus_tag="VQU19_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET2480486.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNVTGVSDHNPAQQQ
                     IELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTIKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     gene            6618..7484
                     /locus_tag="VQU19_001237"
     CDS             6618..7484
                     /locus_tag="VQU19_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2480487.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            7481..8239
                     /locus_tag="VQU19_001238"
     CDS             7481..8239
                     /locus_tag="VQU19_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2480488.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEDLTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            8329..10089
                     /gene="dnaG"
                     /locus_tag="VQU19_001239"
     CDS             8329..10089
                     /gene="dnaG"
                     /locus_tag="VQU19_001239"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HET2480489.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVTFMEAVQILGQRVGIEVEKPLYSEQ
                     KPASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKKSSGKTSEIYLMEGFMDVIAAYRAGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAAILKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYTQIEQIVNESRQVQRQNRMERISRPTPITMPVT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            10092..11201
                     /gene="rpoD"
                     /locus_tag="VQU19_001240"
     CDS             10092..11201
                     /gene="rpoD"
                     /locus_tag="VQU19_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HET2480490.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            11215..11544
                     /locus_tag="VQU19_001241"
     CDS             11215..11544
                     /locus_tag="VQU19_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HET2480491.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            11659..12702
                     /gene="cpoA"
                     /locus_tag="VQU19_001242"
     CDS             11659..12702
                     /gene="cpoA"
                     /locus_tag="VQU19_001242"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HET2480492.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAVLKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            12718..14043
                     /locus_tag="VQU19_001243"
     CDS             12718..14043
                     /locus_tag="VQU19_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET2480493.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGILIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGALYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFRTVLYLPQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            14074..14250
                     /locus_tag="VQU19_001244"
     CDS             14074..14250
                     /locus_tag="VQU19_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HET2480494.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            14309..14443
                     /locus_tag="VQU19_001245"
     CDS             14309..14443
                     /locus_tag="VQU19_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HET2480495.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            14507..15817
                     /gene="obgE"
                     /locus_tag="VQU19_001246"
     CDS             14507..15817
                     /gene="obgE"
                     /locus_tag="VQU19_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HET2480496.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLSENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            15827..15985
                     /locus_tag="VQU19_001247"
     CDS             15827..15985
                     /locus_tag="VQU19_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480497.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            17035..18294
                     /locus_tag="VQU19_001248"
     CDS             17035..18294
                     /locus_tag="VQU19_001248"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HET2480498.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            18310..18861
                     /locus_tag="VQU19_001249"
     CDS             18310..18861
                     /locus_tag="VQU19_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2480499.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLFIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            18854..20131
                     /locus_tag="VQU19_001250"
     CDS             18854..20131
                     /locus_tag="VQU19_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET2480500.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIDRLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            20147..21007
                     /locus_tag="VQU19_001251"
     CDS             20147..21007
                     /locus_tag="VQU19_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HET2480501.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
BASE COUNT         6551 a         3678 c         4805 g         6380 t
ORIGIN      
        1 ccagttagga cactttgaat gatttcttag ttttatatat tatacttttc tcaggagaaa
       61 gctagatgta cagacgtttg agagatttga gggaagatca cgatttgacc caaaaacaaa
      121 tagctaaaat actttcgttt acaaactcag cttatgctaa aattgaacgg ggtgagcata
      181 cgttaacagc agatgtattg gtaactctct caaactttta cgatgtcagt acagactacc
      241 tattggaatt gacagatttt cctgataaaa ttcgctttag aaaataatct cctcaatttc
      301 atagagtgtg aaaatgagga gattttttat ttgttctttg aaaattaaat agtccaaaat
      361 ggtactttcc tcatttgtgg agcaaatttg aatggctcgc catgataaga gcgattttaa
      421 agccatcaat aaaatagagc gatactttat atgccatgat acaaatgata tacaatgata
      481 cttctgaccg ttcaggctgc catcgtaaaa gagcagcaag tgaaattctt atgatgactt
      541 catcagtcat gccacgttga atgtgtgagt ttgttagaga aacgcaatta atcctcaaaa
      601 ggttccccga accttttgag ttccacagac gcatcacgtg gagtgtgtaa gcttgttgct
      661 aaaagcgtaa aaaccttgga acgaaaggaa taatagactt cctgcgaaac aaaaatacaa
      721 tacaataaaa ctatggatga tgaagcaagt aaacaattaa gcgatagccg tttcaagagc
      781 cttgtaggtg ttcagcgcac gagatgttag ctgtgttaaa aacagcttat caacgcaacg
      841 taaacgcgca aaaggtggac gaaaaaccaa attaagccta gacgatctcc tcatggtaac
      901 tattcaatac atgcgagaat agcgcactta tgaacaaatt gcggctgatt ttggcattca
      961 cgaaagcaac ataattagtc ggaggtcaat ggattgaagc aactcttatt caaaatggtt
     1021 ttacgatttc aaattctgcc ttaattctgt aaaaacagta aaattcgaag gattgtaagg
     1081 taagagtttt tttctttctg aaaaaatggt ataatagcaa tcaaaactag aaaataaaac
     1141 ggaatttgga acagatttgt ctgtatccta gtagagtggt gatactatga agattagtaa
     1201 gaggcactta ttaaattatt ccatcttgat tccctacttg cttttatcta ttttgggctt
     1261 gattgtggtc tattcgacca ccagtgctat tttaattgaa gaaggcaaga gcgccttgca
     1321 gttggttcga aaccaaggaa tcttttggat tgttagtttg atactgattg ccttaattta
     1381 taaattgaga ctagattttt tgagaaatga gcgactaatc attttagtta tattaataga
     1441 aatgctttta ttgttcttgg ctcgttttat tggtatttca gtaaacgggg catacggttg
     1501 gatttcggtt gcaggagtaa ctattcagcc agctgagtac ttaaaaatca ttattatttg
     1561 gtatttagct caccgattct ccaaacagca agaagaaata gctacttatg attttcaagt
     1621 tttgactcaa aatcaatggc ttccccgtgc ttttaatgat tggcgattcg ttctcctagt
     1681 tctgattgga agtttgggaa ttttccctga tttaggaaat gcgactattt tagtcttggt
     1741 ttccttgatt atgtatacag ttagtggaat cgcttatcgc tggttttcaa ccattctggc
     1801 gctcgtatct gccgcttctg tctttgtctt gaccactatc agcctaatcg gtgttgagac
     1861 cttttcaaaa attccagtat ttggctatgt agccaaacgc tttagtgcct tttttaatcc
     1921 ttttgccgat cgtgctgatg caggtcacca gttagctaat tcttattttg ccatggtcaa
     1981 tggtggttgg tttggtctag gtcttggaaa ctcgattgaa aaacgaggtt atttgccaga
     2041 agctcataca gactttgtct tttctatcgt gattgaagaa tttggctttg ttggtgccag
     2101 tcttatttta gctctcttgt ttttcatgat tttgcggatt atcttggtcg gtattcgagc
     2161 ggagaatcct ttcaatgcca tggttgcact cggtgtcgga gggatgatgt tggttcaggt
     2221 atttgtcaat atcggaggga tttcgggctt gattccatct acaggagtaa ccttcccctt
     2281 cttatcccag ggtggaaata gtcttctagt cttatcagtg gcagtagcct ttgtcttaaa
     2341 tattgatgcc agtgaaaaac gcgctaagtt gtaccgagaa ttggaaaatc aaccaatgaa
     2401 ccttctgttg aagtaggata aagaaaggat agtttatgtc tcttcaaaaa ttagaaaatt
     2461 ctagtaataa aagtgttgtg caagaagaag tcttgattct aacagaatta ctggaagata
     2521 ttactaaaaa tatgcttgcc ccagagacct ttgaaaaaat aatacagttg aaagaattat
     2581 caacgcagga agattatcaa ggtctaaacc gtctagtgac tagcttatca aatgatgaaa
     2641 tggtctatat ttcacgctat ttctctatct tgcctctttt gattaatatt tcagaggatg
     2701 tggatttagc ttatgaaatc aatcatcaaa ataatattga tcaggactat ttaggtaaat
     2761 tatctacaac gattaaattg gtagcagaaa aggaaaatgc cgttgagatc ctagaacact
     2821 tgaatgttgt tccggttttg acagcccatc caacacaagt gcaacgcaaa agtatgttgg
     2881 atttaacaaa tcatattcat agtcttttgc gtaaataccg tgatgttaag ttggggttga
     2941 tcaataaaga taaatggtac aatgatttgc gtcgttacat cgaaattatc atgcagacag
     3001 acatgattcg tgagaaaaaa ttaaaagtga ctaacgaaat cacgaatgct atggaatatt
     3061 ataacagctc ctttttgaaa gctgtacctc atttgacgac ggagtataag cgcttagcgc
     3121 aagcgcatgg tctgaattta aaacaggcta aaccaatcac catgggtatg tggataggtg
     3181 gtgaccgtga tggaaatcca tttgttacag caaagacctt gaagcagtct gcactcactc
     3241 aatgtgaagt catcatgaac tactatgata aaaagattta ccaactttat cgtgaatttt
     3301 ctctttcaac tagcattgtc aacgtcagca agcaagtcag agaaatggct cgtcaatcca
     3361 aggataactc gatttaccgc gaaaaagagc tttaccgtcg tgccttgttt gatattcaat
     3421 caaaaattca ggcaactaaa acctatctga ttgaggatga agaagttggg actcgttatg
     3481 aaaccgccaa tgatttctac aaggatttga ttgccattcg agattctcta ctagagaata
     3541 agggcgagtc cttgatttca ggtgattttg tggaattatt gcaggcagta gagatatttg
     3601 gtttttacct agcatcaatt gatatgcgac aagactctag cgtctatgaa gcctgtgtgg
     3661 cagaactctt gaaatcagca ggaattcatt ctcgttatag cgagttgagc gaagaagaaa
     3721 agtgtgacct tcttttgaaa gaattagaag aagatccccg aattctttct gcgactcacg
     3781 cagaaaaatc agaattatta gcaaaagaac tagctatttt taagacggct cgtgttttga
     3841 aagataagtt gggagatgat gtcatccgtc agaccatcat ttcacatgca accaaccttt
     3901 ctgatatgct agaattagct attctgttaa aagaagtagg actggtggat acggaaaggg
     3961 cgcgtgttca gattgttccc ctttttgaaa caattgaaga cttggatcat tcagaggaaa
     4021 caatgagaaa atatctttct cttagccttg ccaaaaaatg gattgactca cgaaataact
     4081 accaagaaat catgcttggc tactctgaca gtaataaaga tggcggttac ttgtcatcat
     4141 gttggaccct ctacaaggct caacaacaat tgactgctat tggagatgaa tttggcgtta
     4201 aggttacctt cttccatggt cgtggtggta ctgtcggtcg tggtggtggg ccaacctatg
     4261 aagccattac atctcaaccg ctcaagtcta tcaaggatcg tatccgtttg acggagcagg
     4321 gtgaagtaat tgggaataaa tacggtaaca aagacgccgc ttactataac cttgaaatgc
     4381 tagtatcggc agctattaac cgtatgatta ctcagaagaa gagcgatacc aataccccaa
     4441 atcgttatga agccattatg gatcaagtag tggaccgtag ttacgatatc taccgtgatt
     4501 tggtctttgg taatgagcat ttctatgatt atttcttcga gtcaagtcca atcaaggcta
     4561 tttcaagttt taatattggt tctcgtccag ccgctcgtaa gactattact gaaatcggtg
     4621 gtttgcgtgc catcccttgg gtattctcat ggtcacagag tcgtgttatg ttccctggat
     4681 ggtacggggt tggttcaagc ttcaaggaat ttatcaataa aaatccagag aatattgcta
     4741 tcttacgaga tatgtaccaa aattggcctt tcttccaatc gcttctttca aatgttgata
     4801 tggttttgtc aaaatcaaat atgaatattg cttttgaata tgctaaactt tgtgaagacg
     4861 agcaagttaa ggccatctat gagattattt taaatgaatg gcaagttact aagaacgtta
     4921 tcttggctat tgaaggacat gacgaactct tagctgacaa tccatatcta aaagctagtc
     4981 tggattaccg tatgccttac tttaatattc tcaactatat tcagttagag ttgattaaac
     5041 gccaacgtcg tggagaattg tccagtgatc aagaacgatt gattcatatc accatcaacg
     5101 gaattgcgac aggattgcgt aattcaggtt gataattttc aagagtgaat gctaaaagtg
     5161 aatatcaaaa aaattctaat agactattga caagtagttt aaaaatgata taatttaacc
     5221 attcagaaaa gtaatcatac aaacttttta gagagtctgt ggtagctgaa aacagataag
     5281 tggcgatgat gaaaattggg ctgaatgcta tttagaattt gaaattataa aaattcggta
     5341 agcacacctt acagtgcatc tcgttattgc gagactgagc gatagggaaa ttccctataa
     5401 ttgaggtggt accgcgcatc gacgtcctca cacaagtttt ttgtgtgagg atttttttga
     5461 tggaggttag tatggaaaga aaacgatggc gtcgcttgtt tagataagtg aaatatgtta
     5521 aaggaaataa aaaggagaaa cagaatgaaa aataaacgtt taattggaat tattgctgca
     5581 ttagcagtct tagtagcagg aagcttgatt tattcttcaa tgaataaatc agaagctcag
     5641 aataataagg atgagaagaa aataaccaag attggtgtgc ttcaatttgt gagccatcca
     5701 tcccttgatt tgatttataa agggatccaa gatggacttg cagaagaagg atataaagat
     5761 gatcaagtta aaattgattt tatgaactca gaaggtgatc aaagtaaggt tgcgacaatg
     5821 agtaaacaat tggttgcaaa tgggaatgac cttgtggttg gtattgcaac accagcagcc
     5881 caagggttgg ctagtgcaac aaaagaccta ccagttatca tggccgctat tacagaccca
     5941 attggtgcta acttggttaa agatttgaaa aaaccaggtg gtaacgttac aggggtatct
     6001 gaccacaatc cagctcaaca acaaattgaa ctcatcaagg ctctgacacc gaatgtgaaa
     6061 acaatcggag ctctttactc aagtagcgaa gacaattcaa aaacacaggt tgaagaattt
     6121 aaggcttatg ctgaaaaagc aggtctgaca gtggaaacat ttgcagttcc ttcaacaaat
     6181 gaaattgcct caactgtcac tgttatgact atcaaggtag atgctatttg ggttccaatt
     6241 gataacacca ttgcatcagg atttccaacg gttgtctcta gcaatcaaag ttctaagaaa
     6301 ccaatttatc ccagtgcgac agctatggta gaagtaggtg gtttggcatc agttgtaatt
     6361 gaccaacatg accttggtgt ggcaacaggt aaaatgattg tgcaagtctt gaaaggtgca
     6421 aaaccagccg ataccccagt caatgtcttt tcaactggta agtcagtcat caataaaaaa
     6481 atagcacaag aactaggtat tactattcct gagtctgttc tcaaagaagc aggacaagtc
     6541 atcgaataaa taaggtaggg aggaggagac tcttcccatt ttttaaaaag atgaatatag
     6601 aaaggattaa ataaaatatg attgtttcca ttatttctca aggatttgtc tgggctattc
     6661 taggtctggg aatctttatg acatttagga ttttaaactt tccagatatg acgacagaag
     6721 gttccttccc tcttggggga gctgttgctg tcactttgat aaccaaaggc gtgaacccat
     6781 ttttagcgac acttgttgct gtaggagcag gttgtttggc tggaatggca gcaggccttc
     6841 tttatacaaa agggaagatc ccaaccttgc tctcagggat tttggtgatg acttcttgtc
     6901 actcaatcat gctcttgatt atgggacgtg cgaatttagg cctgcttgga accaagcaaa
     6961 ttcaggatgt tttgcctttt gattcggatt tgaatcaact cttgacaggt ctcatctttg
     7021 tgagcattgt tattgctctc atgctctttt tcttggacac taaactcgga caagcctata
     7081 ttgctacagg ggataatcct gatatggcta gaagtttcgg gattcatact ggacgcatgg
     7141 agctcatggg cttggtctta tcaaatggtg tgattgccct tgcaggtgcc ctcattgctc
     7201 agcaagaagg ctatgccgat gtgtctcgag ggatcggggt tatcgttgtg gggcttgcaa
     7261 gtttgattat tggagaagtt attttcaaga gtttgagctt ggcagagcgt ttggttacta
     7321 tcgttgtagg ttctatcgct tatcaatttt tagtgtgggc agttatcgca cttggcttta
     7381 atacaagtta ccttcgttta tacagtgcct tgattttagc agtctgcctc atgattccaa
     7441 catttaagca aacaatcttg aaaggagcca agttaagcaa atgacagcaa ttgtagaatt
     7501 aaaaaatgca accaaaattg ttaaaaatgg ctttgatgaa gaaaagatta ttttaaatga
     7561 tgtttcctta gaaatttttg aacgggactt tatcacgatt ttgggcggaa atggtgctgg
     7621 aaaatcaacc ctctttaaca ctatagcagg gaccttatca ctaactagtg gaactatccg
     7681 tattttaggt gaagatctca ctaagttttc acccgagaag cgtgccaagt acctgtctcg
     7741 tgtcttccaa gatccaaaga tggggacagc tccccgtatg acggtcgctg aaaatctttt
     7801 aatcgccaag tttcgtggtg agaagcgtgg attgttacca cgacgcttga ctagctataa
     7861 ggatgaattt caggcaacca ttgaaaaagt aggaaatggt cttgagaaac acttgaatac
     7921 accgattgag ttcttatcag gtggacaaag acaggctttg agtctcttga tggcaacctt
     7981 gaagcgacct gaattactcc tgttagatga gcatactgct gccctggatc caaagactag
     8041 tgttgctttg atggaattga cagatgaatt tgttaagaaa gatcagctaa cagcccttat
     8101 gattactcat catatggaag atgctctcaa atacggcaat cgcttgattg tcatgaaaga
     8161 aggacggatt atccaagatt taaaccaaga agaaaaagca aaaatgaaaa tctctgatta
     8221 ttatcaactc tttgaataaa gtagggaaaa tgagtgaaat ggtttacttt ttttctgaaa
     8281 taaagtatac tatataaagt aaactatgat aacatggagg tattgtgtat ggttgacaaa
     8341 caagtcattg aagaaatcaa aaacaatgcc aacattgtgg aagtcatagg agatgtgatt
     8401 tctttacaaa aggcaggacg gaactatcta gggctctgtc cttttcatgg tgaaaaaaca
     8461 ccttctttca acgttgtaga ggacaagcag ttttaccact gttttggttg tggtcgctca
     8521 ggtgatgtct ttaaattcat cgaggagtac caaggggtta cctttatgga ggctgtccaa
     8581 atcttaggtc agcgtgtcgg gattgaggtt gaaaaaccgc tttatagtga acagaagcca
     8641 gcctcgcctc accaagctct ttatgatatg cacgaagatg cggctaaatt ttaccatgct
     8701 attctcatga caacgactat gggcgaagag gccagaaatt acctttatca gcggggtttg
     8761 acagatgaag tgcttaaaca tttttggatt ggtttagcac ctccagaacg aaactatctc
     8821 tatcaacgtt tgtctgatca gtatcgtgaa gaggatttac tggattcagg cctgttttat
     8881 ctctcggatg ccaatcaatt tgtagacacc tttcacaatc gcattatgtt tcccctgaca
     8941 aatgaccaag gaaaggtcat tgccttctca ggtcgtatct ggcaaaaaac ggattcacaa
     9001 acttctaagt ataaaaacag ccgatcgact gcaattttta acaaaagtta cgaattatat
     9061 catatggata gggcaaaaaa atcttctgga aaaactagtg agatttacct gatggaagga
     9121 ttcatggatg ttattgcagc ctatcgggct ggaatcgaaa atgctgtggc gtcgatggga
     9181 acggccttga gtcgagagca tgttgagcat ctgaaaaggt taaccaagaa attggttctt
     9241 gtttacgatg gagataaggc tgggcaagcc gcgatattga aagcattgga tgaaattggt
     9301 gatatgcctg tgcaaatcgt tagcatgcct gataacttgg atcctgatga gtatctacaa
     9361 aaaaatggtc cagaagactt ggcctatcta ttaacaaaaa ctcgtattag tccgattgag
     9421 ttctacattc atcagtacaa acctgaaaac agtgaaaatc tgcaggctca gattgagttt
     9481 attgaaaaaa tagctccctt gattgttcaa gaaaagtcca tcgctgctca aaacagctat
     9541 attcatattt tagctgacag tctggcgtcc tttgattata cccagattga gcagattgtt
     9601 aatgagagtc gtcaggtgca aaggcagaat cgcatggaaa gaatttccag accgacgcca
     9661 atcaccatgc ctgtcaccaa gcagttatcg gctattatga gggcagaagc ccatctactc
     9721 tatcggatga tggaatcccc tcttgttttg aacgattacc gtttgcgaga agactttgca
     9781 tttgctacac ctgaatttca ggtcttatat gacttgcttg gccagtatgg aaatcttcct
     9841 ccagaagttt tagcagagca gacagaggaa gttgaaagag cttggtacca agttttagct
     9901 caggatttgc ctgctgagat atcgccgcag gaacttagtg aagtagagat gactcgaaac
     9961 aaggctctct tgaatcagga caatatgaga atcaaaaaga aggtgcagga agctagccat
    10021 gtaggagata cagatacagc cctagaagaa ttggaacgtt taatttccca aaagagaaga
    10081 atggagtaat aatggcaaca aaacaaaaag aagtaacaac atttgacgta caggtagcag
    10141 aatttatccg taatcataag caaaaaggga cagcaacaga tgatgaaatc aatgcaagtc
    10201 tggttattcc ttttaccttg gacgctgatg ggattgaaga tctcttgcaa cggattcagg
    10261 atgcagggat ttctatcaca gataacgaag gaaatccaag tgcgcgtgtt cttagcaatg
    10321 aagaagaacc agaactcagc gatgaggact tgattggatc aacttctgct aaggtcaatg
    10381 accctgtccg tatgtacttg aaagaaatag gggtcgttcc tctcttgacc aatgaagagg
    10441 agaaagagtt ggcactggct gttgaagctg gcgatatcga agccaaacaa cgtcttgcgg
    10501 aagccaatct tcgtttggtt gtttccattg ccaaacgcta tgtcggtcgt ggcatgcagt
    10561 tccttgactt gattcaagaa ggaaatatgg gcttgatgaa ggcggttgac aagtttgact
    10621 attctaaagg gttcaagttt tcaacttatg caacttggtg gattcgtcag gctatcactc
    10681 gtgctattgc ggaccaagct cgtaccatcc gtatcccagt tcacatggtt gaaactatca
    10741 ataaattggt tcgtgaacag cggaatctcc ttcaagaatt ggggcaagat ccgacaccag
    10801 aacagattgc tgaacgaatg gatatgacac ctgataaggt tcgtgaaatc ttgaagattg
    10861 cccaagaacc agtatctctt gaaactccta tcggtgaaga ggacgatagc caccttggag
    10921 actttatcga agatgaagtg attgaaaatc cagtggatta tacgactcgt atcgtcttgc
    10981 gtgagcaatt ggatgaaatc ttagatactc ttacagaccg tgaagaaaat gttctgcgtc
    11041 tacgttttgg actagatgat ggaaaaatgc gcacacttga agatgtgggg aaagtcttta
    11101 acgtaactcg tgagcgtatc cgtcagattg aagcaaaggc tttgagaaaa ctacgccaac
    11161 caagtcgcag caaaccgctt cgtgatttta ttgaagacta agagtgagga aaatatggct
    11221 tatacagaag agcaaattga aaacatcaaa acacggattt taacagcctt ggaagaagtc
    11281 atcgaccctg agttgggaat cgatattgtc aatcttggtt tgatctatga gattcgtttt
    11341 gacggtgaca cagggcaaac agagattgac atgactttga caactatggg ttgtccctta
    11401 gcagaccttt tgacagacca gatttatgat gctatgatag aggttccaga agtaacggat
    11461 actgaggtta aattagtctg gtatccagcc tggacagttg aaaaaatgag tcgctatgcc
    11521 cgcattgccc taggcattaa gtaaacatat aaaagcatgt gagagactag aggaaaagcg
    11581 aggaaatttc ccctcttttc ctctagtctc tcctttcttt tgctgatttt attcaaagaa
    11641 aatgatataa tagtagttat ggagaaaaag aaattacgca tcaatatgtt gagttcaagt
    11701 gagaaagtag caggacaggg agtttcaggt gcttaccgtg aattagttcg tcttcttcac
    11761 cgtgctgcca aggaccaatt gattgttaca gaaaatcttc caatcgaggc agatgtgact
    11821 cactttcata cgattgattt tccctattat ttatcaacct tccaaaagaa acgctcaggg
    11881 agaaagattg gctatgtgca tttcttgcca gctacacttg aaggaagttt gaaaattcca
    11941 tttttcttaa agggaattgt gaaacgctat gtattttctt tttacaaccg gatggagcac
    12001 ttggttgtgg tcaatcctat gtttattgag gatttggtag cagctggtat tccacgtgaa
    12061 aaagtgacct atattcctaa ctttgtcaac aaggaaaaat ggcatcctct accacaagaa
    12121 gaggtagtca gactgcgcac agatcttggt cttagtgaca atcagtttat cgtagtaggt
    12181 gctgggcaag ttcagaaacg taaagggatt gatgacttta tccgtctggc tgaggaattg
    12241 cctcagatta cctttatctg ggctggtggc ttctcttttg gtggtatgac agatggttat
    12301 gaacactata agaaaattat ggaaaatccc cctaaaaatt tgatttttcc aggcattgta
    12361 tcgccagagc ggatgcgcga attgtatgct ctagcggatc ttttcttgtt gcctagttac
    12421 aatgagctct ttcctatgac tattttagaa gctgcgagtt gtgaggctcc tattatgttg
    12481 cgtgatttag atctctataa ggtgattttg gagggaaatt atcgggcgac agcgggtaga
    12541 gaagagatga aagaggctat tttggaatat caagcaaatc ctgctgtctt aaaagatctc
    12601 aaagaaaagg ctaagaatat ttccagagag tattctgaag agcatctgtt acaaatctgg
    12661 ttggactttt atgagaaaca agccgcttta gggagaaagt aaaaagtgag gtaatctatg
    12721 cgaattggtt tatttacaga tacctatttt cctcaggttt ctggtgttgc gaccagtatt
    12781 cgaaccttga aaacagaact tgaaaagcag ggacatgctg tttttatctt tacgacgaca
    12841 gataaggatg tcaatcgcta cgaagattgg caaattatcc gcattccaag tgttcctttc
    12901 tttgctttta aggatcgtcg ctttgcctac cgaggtttta gcaaggcact tgaaattgct
    12961 aaacagtatc agctagatat tatccatact cagacagaat tttctcttgg cctgttgggg
    13021 atttggattg cgcgtgaatt gaaaattcca gtcatccata cctatcacac ccagtatgaa
    13081 gactatgtcc attatattgc taaggggata ttgatccggc cgagtatggt caagtatctg
    13141 gttagaggtt tcctgcatga tgtggatggg gttatttgcc ctagtgagat tgtccgtgac
    13201 ttgctatctg attataaggt caaggttgaa aaacgggtca ttcctactgg gattgaatta
    13261 gccaagtttg agcgtccgga aatcaagcag gaaaatttga aagaactgcg tagtaaacta
    13321 gggattcaag atggtgaaaa gacgttgctt agtctttcga gaatctccta tgaaaaaaat
    13381 attcaagcag ttttagcagc ctttgctgat gttctgaaag aggaagacaa ggttaaactg
    13441 gtagtagctg gggatggccc ttatctgaat gacctcaaag agcaagccca gaacctagag
    13501 attcaagact cagtcatctt tacagggatg attgctccta gtgagacggc tctttactat
    13561 aaagcggcgg atttcttcat ttcggcatcg acaagcgaaa cgcaaggttt gacctacttg
    13621 gaaagcttag ccagtggaac acctgtcatt gctcacggaa atccttattt gaacaacctc
    13681 atcagtgata aaatgtttgg agccttgtac tatggagaac atgatttggc tggtgctatt
    13741 ttggaagccc tgattgcaac accagacatg aatgagcata ccttatcaga gaaattgtat
    13801 gagatttcag ctgagaactt tgggaaacga gtgcatgagt tttatctgga tgccattatt
    13861 tcaaataact tccagaaaga tttggctaaa gatgatacgg tcagtcagcg tatctttagg
    13921 acagttttgt atcttccgca acaggtggtt gctgtacctg taaaaggatc tagacgcatg
    13981 ttgaaggctt caaaaacaca gttgatcagt atgagagact attggaaaga ccatgaagaa
    14041 tagaaagagg aacagctatg aaaaaaacaa ttaatgagaa gcggtcgtga taaaaagatt
    14101 gcgggtgttt gtgctggggt ggcccattat ctggatatgg atccgactat cgttcaagtc
    14161 atttggggtg ttcttacttg ctgttacgga gctggaattg tagcttacat tattttatgg
    14221 attatcgcac cagtagcaac tgactattga aaactagctc aattcatgct aagataatag
    14281 aaaatagaat gtaacgaagg agagaaaaat ggcatttgga gataatggaa atcgtaaaaa
    14341 aactatgttt gagaaaataa ccttgtttat cgtgattatc atgctagtag caagtttatt
    14401 gggaattttt gcaactgcaa ttggtgccct cagtaatcta taaaatagat tcaagaaaat
    14461 ttagtgactg ggatttccca gccctttttt aaagtgagaa gaaataatga gtatgttttt
    14521 agatacagct aagattaagg tcaaggctgg taatggtggc gatggtatgg ttgcctttcg
    14581 tcgtgaaaaa tatgtcccta atggaggccc ttggggtggt gatggtggtc gtggaggcaa
    14641 tgtggtcttc gttgtagacg aaggactacg taccttgatg gatttccgct acaatcgtca
    14701 tttcaaggct gattctggtg aaaaagggat gaccaaaggg atgcatggtc gtggtgctga
    14761 ggaccttaga gttcgagtac cacaaggtac gactgttcgt gatgcggaga ctggcaaggt
    14821 tttaacagat ttgattgaac atgggcaaga atttatcgtt gcccacggtg gtcgtggtgg
    14881 acgtggaaat attcgtttcg cgacaccaaa aaatcctgca ccggaaatct ctgaaaatgg
    14941 agaaccaggt caggaacgtg agttacaatt ggaactaaaa atcttggcag atgtcggttt
    15001 agtaggattc ccatctgtag ggaagtcaac acttttaagt gttattacct cagctaagcc
    15061 taaaattggt gcctaccact ttaccactat tgtaccaaat ttaggtatgg ttcgcaccca
    15121 atcaggtgaa tcctttgcag tagccgactt gccaggtttg attgaagggg ctagtcaagg
    15181 tgttggtttg ggaactcagt ttctccgtca catcgagcgt acacgtgtta tccttcacat
    15241 cattgatatg tcagctagcg aaggccgtga tccatatgag gattacctag ctatcaataa
    15301 agagctggag tcttacaatc ttcgcctcat ggagcgtcca cagattattg tagctaataa
    15361 gatggacatg cctgagagtc aggaaaatct tgaagaattt aagaaaaaat tgtctgaaaa
    15421 ttatgatgaa tttgaagagt taccagctat cttcccaatt tctggattga ccaagcaagg
    15481 tctggcaaca cttttagatg ctacagctga attgttagac aagacaccag aatttttgct
    15541 ctacgacgag tccgatatgg aagaagaagc ttactatgga tttgacgaag aagaaaaagc
    15601 ctttgaaatt agtcgtgatg acgatgcgac atgggtactt tctggtgaaa aactcatgaa
    15661 actctttaat atgaccaact ttgatcgtga tgaatctgtc atgaaatttg cccgtcagct
    15721 tcgtggtatg ggggttgatg aagcccttcg tgcgcgtgga gctaaagatg gggatttggt
    15781 ccgcattggt aaatttgagt ttgaatttgt agactaggag actggtatgg gagataaacc
    15841 gatatctttc cgagatgcgg atggtaattt tgtttccgcc gcagacgttt ggaatgaaaa
    15901 gaaattggaa gaactattta atcgtctcaa tccaaatcgt gccttgagat tggcacgaac
    15961 taaaaaggaa aatccatctc agtaaagaag ctaaaaaatc ccgtgcctca tcagacacgg
    16021 gattttgtgg tacgacaggc atgtatagca aactgaatct ggaatagcac agcatatctt
    16081 ctaaaatatt gttataaatt gatttgaatt tcaaaattaa attgtttgat tcttatctca
    16141 atttgttata gtatatctga tgtcaaagtt ctcggcgagt caaatagcga ttcccaagcc
    16201 tgactatcgt gaggtagcgg attaaaatgg tctggggata gaccgtttta agtctgacgc
    16261 tggaaataag aattgtcaga agaagggata gcgaaatcgt ggctctacga acaggaacgt
    16321 gataataagg cgtatatagc ggataagagg gcctcaaact ctaaagtcca aaaaggtagt
    16381 cgtaacctat atgcgtaaat cacgagagta attgaattcg tactaagatt ttctattttc
    16441 actgtaacct tttaacgtcc ttatatcttg tatacacgag gaaagatgta cgacttatcc
    16501 cgtgaggtct atcactataa agagaaaacg acagatagaa gtgatcctga gtcacggtta
    16561 tctttaaaat agattgtctg ataggacggt atgtataaaa cgcttctgtg aactgagaga
    16621 agggggagaa gttcttgcta aaatttagtt gaacagccgt attccgatac ttagataaga
    16681 gatctagtct tagctcctac tcagttttag gggataaaaa aggggaaata gcgattcgag
    16741 aaagattata ctcttcgaaa atctcttcaa atcacgtcaa tatcgccttg ccgtatgtgt
    16801 aggatactga ctacgtcagt tccatctaca acctcaaaac agtgttttga gcaacctgcg
    16861 gctagtttcc tagtttgatc tttgattttc attgagtatt agtaattcag ttactaactc
    16921 gtcaactctg atttatccaa taaaattgaa aaggatggaa aaaaggataa atttatgata
    16981 tactttattt tgaagacctt attagaaatc ttgaaagagt attgaaaact tagaatgaga
    17041 aaaattgtta tcaatggtgg attaccactg caaggtgaaa tcactattag tggtgctaaa
    17101 aatagtgtcg ttgccttaat tccagctatt atcttggctg atgatgtggt gactttggat
    17161 tgcgttccag atatttcgga tgtagccagt cttgtcgaaa tcatggaatt gatgggagct
    17221 actgttaagc gttatgacga tgtattggag attgacccaa gaggtgttca aaatattcca
    17281 atgccttatg gtaaaattaa cagtcttcgt gcatcttact atttttatgg gagcctctta
    17341 ggccgttttg gtgaagcgac agttggtcta ccgggaggat gtgatcttgg tcctcgtccg
    17401 attgacttac accttaaggc gtttgaagct atgggtgcca ctgctagcta cgagggagat
    17461 aacatgaagt tatctgctaa agatacagga cttcatggtg caagtattta catggatacg
    17521 gttagtgtgg gagcaacgat taatacgatg attgctgcgg ttaaagcaaa tggtcgtact
    17581 attattgaaa atgcagcccg tgaacctgag attattgatg tagctactct cttgaataat
    17641 atgggtgccc atatccgtgg ggcaggaact aatatcatca ttattgatgg tgttgaaaga
    17701 ttacatggga cacgtcatca ggtgattcca gaccgtattg aagctggaac atatatatct
    17761 ttagctgctg cagttggtaa aggaattcgt ataaataatg ttctttacga acacctggaa
    17821 gggtttattg ctaagttgga agaaatggga gtgagaatga ctgtatctga ggacagcatt
    17881 tttgtcgagg aacagtctaa tttgaaagca atcaatatta agacagctcc ttacccaggc
    17941 tttgcaactg atttgcaaca accgcttacc cctcttttac taagagcgaa tggtcgtggt
    18001 acaattgtcg atacgattta cgaaaaacgt gtaaatcatg tttttgaact agcaaagatg
    18061 gatgcggata tttcgacaac aaatggtcat attttgtaca cgggtggacg tgatttacgt
    18121 ggggccagtg ttaaagcgac cgacttaaga gctggggctg cactagtcat tgctgggctt
    18181 atggctgaag gtaaaactga aattaccaat atcgagttta tcttacgtgg ttattctgat
    18241 attatcgaaa aattacgtaa tttaggagcg gatattagac ttgttgagga ttaaaccgta
    18301 gaggtgttta tgaatatttg gaccaaatta gcaatgtttt ctttttttga aacggatcgc
    18361 ttgtatttgc gtcctttctt ttttagtgat agtcaggact tccgcgagat agcttcaaat
    18421 ccagaaaatc ttcaatttat tttcccaacg caggcaagtc tggaagaaag tcaatatgca
    18481 ctggccaatt actttatgaa gtcccctttg ggagtgtggg caatttgtga ccagaaaaat
    18541 caacaaatga ttggttctat taaatttgag aagttagatg aaatcaaaaa agaagctgag
    18601 cttggctatt ttttgagaaa agatgcttgg tcgcaaggat ttatgacaga ggttgttaga
    18661 aaaatttgtc agctttcttt tgaggaattt ggcttaaaac aattatttat cattacccac
    18721 cttgaaaatg aagctagcca aagagttgct cttaagtctg gatttagttt gttccgtcag
    18781 tttaagggaa gtgatcgtta cacaagaaaa atgcgggatt atcttgaatt tcggtatgta
    18841 aaaggagagt tcaatgagta agcatcagga aattctaagc tatttggagg aattaccagt
    18901 aggtaaaagg gtcagtgttc gtagcatttc gaatcatcta ggagttagtg atggaacagc
    18961 ctatcgagct attaaagaag ctgaaaaccg tggaattgtg gagacccgtc ctagaagtgg
    19021 aacaattcgt gttaaatccc agaaagttgc tatagataga ttaacgtttg ctgaaattgc
    19081 agaagtgact tcttctgagg ttctggctgg gcaagaaggt ttagagagag aatttagtaa
    19141 gttttcaatt ggtgccatga ctgaacaaaa tatcttgtct taccttcatg atggggggct
    19201 cttgattgtc ggagaccgaa cccgtattca gttgctagcc ttggaaaatg aaaatgcagt
    19261 tctggttaca gggggatttc aggttcatga tgatgtgctt aaactggcca atcaaaaagg
    19321 gattcctgtt ctaagaagta agcatgatac ctttaccgtc gctaccatga tcaataaagc
    19381 cttgtcaaat gtccaaatca agactgatat tctgacagtt gagaaacttt atcgccctag
    19441 tcatgagtat ggttttctga gagagacaga tacagttaaa gattatttgg acttggttcg
    19501 taagaatcgt agcagccgtt tccctgttat caatcaacat caggtcgttg ttggcgttgt
    19561 aaccatgaga gacgctggtg ataaatcacc aagcacgaca attgataagg ttatgtctcg
    19621 tagtctattt ttggttggat tatcgacaaa tattgccaat gtgagtcaac ggatgatcgc
    19681 agaagacttt gaaatggtac cagttgttcg aagcaatcaa actttgcttg gcgttgtgac
    19741 gcgacgagat gtcatggaga agatgagccg ttcccaagtt tcggctctac caactttttc
    19801 tgagcagatt ggacaaaagc tctcttatca ccatgatgaa gtagtcatta cagtggaacc
    19861 ctttatgcta gaaaaaaatg gagttttggc taatggtgta ttggcagaaa ttctgaccca
    19921 catgacccaa gatttagttg ttaatagtgg tcgcaatctc attatcgagc agatgctgat
    19981 ctactttttg caggccgttc agatagatga tatattgcgc attcaggcac ggattattca
    20041 tcatacgaga cggtcagcta taattgatta cgatatttat catggtcacc agattgtttc
    20101 aaaagcaaat gtgactgtta aaattaatta gaaactagga gaaaagatga taacattaaa
    20161 atcagctcgt gaaatcgaag ctatggacaa ggctggtgat tttctagcaa gtattcatat
    20221 aggcttacgt gatttgatta agccaggcgt agatatgtgg gaagttgaag aatatgtccg
    20281 ccgtcgttgt aaagaagaaa atttccttcc acttcagatt ggggttgacg gtgccatgat
    20341 ggactatcct tatgctacct gttgctctct taacgatgaa gtggctcacg ctttccctcg
    20401 tcattatatc ttgaaagatg gtgatttgct caaagttgat atggttttgg gaggtcccat
    20461 tgctaaatct gacctaaatg tctcaaaatt aaacttcaac aatgttgaac aaatgaaaaa
    20521 atacactcag agttattctg gtggtttagc agactcatgt tgggcttatg ctgttggtac
    20581 accgtccgaa gaagtcaaaa acttgatgga tgtaaccaaa gaagctatgt acaagggtat
    20641 tgagcaagct gttgttggaa atcgtatcgg tgatatcggt gcggctattc aagaatacgc
    20701 tgaaagtcgt ggttacggtg tagtgcgtga tttggttggt catggtgttg gcccaactat
    20761 gcacgaagaa ccaatggttc ctaactatgg tattgcaggt cgtggactcc gtcttcgtga
    20821 aggaatggtc ttaaccattg aaccaatgat caatacaggc gattgggaaa ttgatacaga
    20881 tatgaaaact ggttgggcgc ataagaccat tgacggtgga ttgtcatgtc agtatgaaca
    20941 ccaatttgtc attacgaaag atggacctgt tatcttgact agccaaggtg aagaaggaac
    21001 ttattaataa aaagtgaaaa gactactgga agtttattat gaaaaaatcc agtagatctt
    21061 ttcataataa aacgcattgt atcaagtgtt aggggctgat atcatgcgtt tttctgcttt
    21121 taagattttt tccaactctg tttgtaagcg catcataaca aagggtctag gattcagggc
    21181 tctcctccta tatactatta gtaaagtaaa actaagggag gatattttag tgtcgcagtc
    21241 tattgttcct gtagagattc cacaatattg tcgttttgat tctaaaaaga gaaatggaat
    21301 tctgtttaat gttcgtattg ccaatcttaa atttaccttt tttagattag acttcctgcg
    21361 aaacaaaaca tggtatagta gttctatgaa tgatgaagca agtaaacaac taac
//
LOCUS       DAVBCA010000034        21312 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.034, whole genome shotgun sequence.
ACCESSION   DAVBCA010000034 DAVBCA010000000
VERSION     DAVBCA010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21312
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.034"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(57..176)
                     /locus_tag="VQU19_001252"
     CDS             complement(57..176)
                     /locus_tag="VQU19_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HET2480502.1"
                     /translation="MDFKSFIIGLVVGIFGPYMYNLIRKIFSKFPKKDTDSTP"
     gene            complement(179..409)
                     /gene="blpU"
                     /locus_tag="VQU19_001253"
     CDS             complement(179..409)
                     /gene="blpU"
                     /locus_tag="VQU19_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HET2480503.1"
                     /translation="MDTKMMSQFSVMDTEMLACVEGGGCNWGDFAKAGVGGAAARGLQ
                     LGIKTGTWQGAATGAAGGAILGGVAYAATCWW"
     gene            complement(478..747)
                     /gene="blpJ"
                     /locus_tag="VQU19_001254"
     CDS             complement(478..747)
                     /gene="blpJ"
                     /locus_tag="VQU19_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpJ"
                     /protein_id="HET2480504.1"
                     /translation="MNTKMLSQLEVMDTEMLAKVEGGYSSTDCQNALITGVTTGIITG
                     GTGAGLATLGVAGLAGAFVGAHIGAIGGGLTCLGGMVGDKLGLSW"
     gene            complement(1214..1411)
                     /gene="blpI"
                     /locus_tag="VQU19_001255"
     CDS             complement(1214..1411)
                     /gene="blpI"
                     /locus_tag="VQU19_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpI"
                     /protein_id="HET2480505.1"
                     /translation="MNTKMMEQFSVMDNEELEIVSGGRGNLGSAIGGCIGAVLLAAAT
                     GPITGGAATLICVGSGIMSSL"
     gene            1693..2280
                     /locus_tag="VQU19_001256"
     CDS             1693..2280
                     /locus_tag="VQU19_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HET2480506.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
                     SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG"
     gene            2273..3862
                     /locus_tag="VQU19_001257"
                     /pseudo
     CDS             2273..3862
                     /locus_tag="VQU19_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864064.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
     gene            3873..5234
                     /locus_tag="VQU19_001258"
     CDS             3873..5234
                     /locus_tag="VQU19_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HET2480507.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVLIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSVIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMDESQKTAL
                     ETQLQRLEKQKEGLGILKQSLEKATDLFSGEDEFGYHNTFMNFTKQSHDIELGITKTN
                     TEVSNQANLANSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTGNPHQSILNRY
                     LIASQGQTQGTAEEPFLSQINQSIASLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTAPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPVITDTREVLITYYVSSDYLLLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     SIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTTKKTYFDYFKDKILT
                     HSD"
     gene            5291..5446
                     /gene="blpC"
                     /locus_tag="VQU19_001259"
     CDS             5291..5446
                     /gene="blpC"
                     /locus_tag="VQU19_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HET2480508.1"
                     /translation="MDKKQNLTSFQELTTTELNQIIGGGWWEDFLYRFNIIEQKNTKG
                     FHQPIQL"
     gene            complement(5490..6830)
                     /locus_tag="VQU19_001260"
     CDS             complement(5490..6830)
                     /locus_tag="VQU19_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET2480509.1"
                     /translation="MNVAWILLYTLVTHGLKIVIFFKVDGISLTFERIFKAFLFKILL
                     AVVFGMLGYMVGNTYLSYFMEPLYGIGLSFLLLRELPKKLLLFYGLFPMILVNLFYRG
                     VSYFVLPFLGQGQVYDDYSFIWLCIIIFNFFISLAFLKWLDYDFTSLRKGILDKDFQK
                     SLTQINWIMGAYYLVIQNLSYFEYEQGIQSTTVRHLILVFYLLFFMGIIKKLDTYLKD
                     KLHERLNQEQDLRYREMERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EIYDSVLKDSSEKLQDNKYDLGRLVNIRDKALKSLLAGKFLKARDKNIVFNVEVPEEI
                     QVEGMSLLDFLTVVSILCDNAIEASVEACQPHVSIAFLKNGAQETFIIENSIKEEGID
                     ISEIFSFGASSKGEERGVGLYTVMKIVESHPNTSLNTTCQDHVFRQVLTVIHIE"
     gene            complement(6844..7581)
                     /locus_tag="VQU19_001261"
     CDS             complement(6844..7581)
                     /locus_tag="VQU19_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2480510.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKEHHITPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANGQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSTRPHRVILYTKTDRLEFTASLEEVLKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINNLH"
     gene            complement(7586..7924)
                     /locus_tag="VQU19_001262"
     CDS             complement(7586..7924)
                     /locus_tag="VQU19_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2480511.1"
                     /translation="MKHMIIQTQKTVYKVNVDDIYYIQTHPTKAHTVQIVTEEASFNM
                     LQNLSNLENQYGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            8201..8530
                     /locus_tag="VQU19_001263"
     CDS             8201..8530
                     /locus_tag="VQU19_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HET2480512.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(8698..9747)
                     /locus_tag="VQU19_001264"
     CDS             complement(8698..9747)
                     /locus_tag="VQU19_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2480513.1"
                     /translation="MKDLFLKRKQAFRKECLCYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEAIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYVISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(9744..10475)
                     /locus_tag="VQU19_001265"
     CDS             complement(9744..10475)
                     /locus_tag="VQU19_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2480514.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            10543..10953
                     /locus_tag="VQU19_001266"
     CDS             10543..10953
                     /locus_tag="VQU19_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HET2480515.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMNATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            10963..11250
                     /locus_tag="VQU19_001267"
     CDS             10963..11250
                     /locus_tag="VQU19_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480516.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIIDQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            11412..11651
                     /locus_tag="VQU19_001268"
     CDS             11412..11651
                     /locus_tag="VQU19_001268"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480517.1"
                     /translation="MHHNLGNSYSIKIKKQTRKLGTDCSKHRFKVVDRTDEVSSKHCF
                     EVVDRTDEVSNHTHDKPTLTWFEEIFEEYHSPFHN"
     gene            complement(12001..13137)
                     /gene="dnaJ"
                     /locus_tag="VQU19_001269"
     CDS             complement(12001..13137)
                     /gene="dnaJ"
                     /locus_tag="VQU19_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HET2480518.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(13342..13695)
                     /locus_tag="VQU19_001270"
     CDS             complement(13342..13695)
                     /locus_tag="VQU19_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000115730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480519.1"
                     /translation="MSVNKNNLSDIADYHEKIKFFEELFNLDYNPTEMLVTVERNGNV
                     IYKEFTEVAVGKSKYDHTSVFKDVMIYFSDHICQELHLYKTQDPHYNKFEFDLAKRSL
                     KITTRDNTTIFISNE"
     gene            complement(13708..15531)
                     /gene="dnaK"
                     /locus_tag="VQU19_001271"
     CDS             complement(13708..15531)
                     /gene="dnaK"
                     /locus_tag="VQU19_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HET2480520.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(16011..16535)
                     /gene="grpE"
                     /locus_tag="VQU19_001272"
     CDS             complement(16011..16535)
                     /gene="grpE"
                     /locus_tag="VQU19_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HET2480521.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(16562..17596)
                     /gene="hrcA"
                     /locus_tag="VQU19_001273"
     CDS             complement(16562..17596)
                     /gene="hrcA"
                     /locus_tag="VQU19_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HET2480522.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFHRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTGLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLEAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQVNVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(17760..18269)
                     /locus_tag="VQU19_001274"
     CDS             complement(17760..18269)
                     /locus_tag="VQU19_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HET2480523.1"
                     /translation="MNSRVEFRIFTIVDLDKEEEYLHEMHLKGWRYRTSRFGLFYFDQ
                     CQPDDVIYRIYDSRFLKKYKHELQDFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMS
                     KGLKWEVMRSRLRSCTTTFLGGLVVCTSLFREDLSMSFFLIFVLYAFLISYLIHGYFR
                     LKRKYRVDE"
     gene            18877..20814
                     /locus_tag="VQU19_001275"
                     /pseudo
     CDS             18877..20814
                     /locus_tag="VQU19_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            20812..21312
                     /locus_tag="VQU19_001276"
                     /pseudo
     CDS             20812..21312
                     /locus_tag="VQU19_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819352.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
BASE COUNT         6698 a         4437 c         3832 g         6345 t
ORIGIN      
        1 attaaagaaa ctcccctgta aattaagcta gcaaatacag gggagaaatt tattttttag
       61 ggggtactat ctgtatcctt tttgggaaat tttgaaaata tttttctaat taaattatac
      121 atataaggac caaatatacc aactactaaa ccaataataa aacttttaaa atccataatt
      181 accaccaaca tgttgctgca taggctacac ctccaagtat agctccaccc gcagcaccag
      241 ttgctgcacc ttgccatgtt cctgttttaa tgcctagttg aagacctctt gctgctgctc
      301 ctccaacacc tgctttggca aaatctcccc aattgcatcc gccaccttca acgcaagcaa
      361 gcatttcagt atccataaca gaaaattgtg acatcatttt tgtatccatg acaaatactc
      421 cttttttaaa aaactaaaat aaatcagaat agaatcctca taattttact ataagtctta
      481 ccaacttagt cccaatttat caccaaccat acctcctaag catgttaatc cacccccaat
      541 tgcaccaatg tgtgctccaa caaatgcacc agcaagtcca gctactccta aagtggccaa
      601 acctgctcca gttccaccag ttataattcc cgtagtgact cctgtaatca gtgcattttg
      661 acaatcagtg gagctatacc ccccttcaac tttcgcaagc atttcagtat ccataacctc
      721 taactgtgac aacatttttg tattcatgat gaatacctcc tttttatttt caatttgtta
      781 ccaaagtctt aaattcaata aacaaataga ttttttatag tatctttttg attttcttaa
      841 aaaagtatat acgtctacta tcttcttaaa ggtagcagta cctatttttt agtctaagat
      901 ttcaataatc ttgagtatct aaaatatctt aatttcgtta ttctccttgc aataaaaagt
      961 tttactatac tatttattaa cttgcagaaa gcaaaaaata ttagtaaata atagtttata
     1021 gttaagtttt ttattcctac caatccatca actaagtaaa gcatcaacga ttacataaac
     1081 gattgataat ataattaaaa ttttgctaac tatcttattc tcatcattct tagataactt
     1141 tgatattttg taagtaagta aataagacag taaattaata gcgataataa tactatattt
     1201 aagaatcata atcttacaaa gaggacataa ttcctgaacc tacacaaata agtgttgctg
     1261 ctcccccagt tatcggacca gtcgcagcag ctaatagtac tgctccaata caaccaccga
     1321 ttgcagatcc taaattgcct cttcctccac taactatttc gagttcttca ttatccataa
     1381 cagaaaattg ttccatcatt tttgtattca tgacaaatac tccttttttc tttttttatt
     1441 tttgtcttgt tgtaactttg ataagtttag tatatcatcg ttttttaaaa tttttcatcc
     1501 agatcttgaa ttgtcatcga aacgtcttga attagctttt ttatttcaag ccacctctaa
     1561 atgtttaaaa aaaataattt ctaatcactt ttttaccatt caggaagttt taatgactat
     1621 tcaagatttc ataaaatatg aacttagttt tatgacataa tagacctatc cactatatga
     1681 aaagaattgc caatgacttc ttataaacgt acatttgttc ctcaaataga tgcgagagac
     1741 tgtggtgtcg ctgccttagc ctcgattgct aaattctatg gttcagattt ttctctagct
     1801 cacttgagag aacttgcaaa gaccaataaa gaagggacga ctgctcttgg cattgtaaaa
     1861 gccgctgatg aaatgggctt tgaaacaaga cctgttcaag cagataaaac gctctttgac
     1921 atgagtgatg tcccctatcc atttatcgtt cacgttaaca aagaaggaaa actccaacat
     1981 tactatgttg tctatcaaac aaagaaagac tatctgatta ttggtgatcc tgacccttct
     2041 gtaaaaatca ctaaaatgtc aaaagaacgc tttttctatg aatggactgg agtagctatt
     2101 tttctagcta ccaaacccag ctatcaaccc cataaagata aaaagaatgg tctactaagc
     2161 aagcttcctt cctctgattt tcaaacaaaa atctctcatt gcttacattg ttctctcaag
     2221 cttattggtc actattatca atataggtgg ttcttactat ctccaaggaa tcttggatga
     2281 atacattcca aatcagatga aatcaacttt aggaatcatc tcagttggtc tggttatcac
     2341 ctaggttatc acctatatcc tccaacaagt catgagcttc tccagagatt atctcctaac
     2401 cgttctgagc cagagattaa gcattgatgt gattttatcc tatattcgcc atatttttga
     2461 acttcccatg tctttctttg cgacacgtcg tacaggagaa atcatttcac ggttcacaga
     2521 tgctaactct attatagatg ccttggcttc taccattctt tctctttttc tggatgtttc
     2581 tattctgatt cttgtagggg gagtcttgct ggcacaaaac cctaatctct tcctcctttc
     2641 tcttctttcc attcctatat acatgttcat catcttttct tttatgaaac cttttgaaaa
     2701 aatgaaccat gatgtcatgc aaagtaattc tatggttagc tctgccatta tcgaagatat
     2761 caacgggatt gaaactataa agtcgctcac gagtgaagaa aatcgctatc aaaatataga
     2821 cagcgaattt gtagattatt tggaaaaatc ctttaagctc agtaaatatt ctattttaca
     2881 aacgagttta aagcagggaa caaaattagt tctgaatatc cttatcctat ggtttggcgc
     2941 tcaattagtc atgtcgagta aaatttctat cggtcagctg attaccttta acacactttt
     3001 ttcttacttt acaactccta tggaaaatat tatcaacctc caaaccaaac tcccatctgc
     3061 gaaggtcgct aataaccgtt tgaacgaagt ctatctagtc gaatctgaat ttcaagttca
     3121 agaaaaccct gtccattcac attttttgat gggcgatatt gaatttgatg acctttctta
     3181 taagtatggt tttggacgag ataccttaac agatattaat ctcacgatta aacaaggaga
     3241 taaggttagc ctagttggag ttagtggttc tggtaaaaca actttagcca aaatgattgt
     3301 caatttcttt gaaccctaca aagggcatat ttccatcaat catcaggata ttaaaaacat
     3361 tgataaaaaa gtcttgcgcc gtcatattaa ttacctaccc caacaagcct atatctttaa
     3421 tggctctatc ttggaaaatt taaccttggg cggtaatcat atgattagcc aagaagatat
     3481 tctaagagct tgtgaattag ctgaaatccg tcaagacatt gaaagaatgc ctatgggcta
     3541 tcaaactcag ctctctgatg gagctggtct atcaggagga cagaagcaac gaatagccct
     3601 cgctcgtgct cttttaacta aatctcctgt tttaatacta gacgaagcta ctagcggtct
     3661 tgatgtcttg actgagaaaa aagttataga taatcttatg tccctaactg ataaaaccat
     3721 tctctttgta gcccatcgtc tcagtatagc cgaacgaact aaccgtgtca ttgttcttga
     3781 ccaggggaaa atcattgaag ttggtagtca ccaagagtta atgcaggcgc aaggcttcta
     3841 ccatcatctg ttcaataaat aaggagaatg tcatgaatcc taatcttttt agaagcgtcg
     3901 agttttatca gagacgttac cataactatg cgacagtgtt aattatacct ctttcattac
     3961 tgtttacttt catcttgatt ttctcccttg ttgccacaaa agaaattact gttacttccc
     4021 aaggagaaat cgcccctaca agtgtcattg catccattca gtcaaccagt gataatccta
     4081 tccttgctaa tcatttagtg gcaaatcaag tagttgaaaa aggtgactta ctcatcaaat
     4141 actctgaaac aatggatgag agtcagaaaa ctgccttaga aactcaatta caaagacttg
     4201 agaagcaaaa agaaggactt ggaattttga aacaaagttt agaaaaagcg actgatcttt
     4261 tttctggcga ggatgagttt ggctaccata atacctttat gaattttact aaacaatccc
     4321 atgatattga actgggtatc acaaagacta acaccgaagt ttcaaatcaa gctaatcttg
     4381 ccaatagcag ttcatcagcc atcgaacaag aaattacaaa agttcaacaa caaattggag
     4441 aatatcaaga gttgagagat gctatcataa ataacagagc acgcttacca actggcaatc
     4501 cgcaccagtc aattttaaat cgttatctta tagcctctca aggacaaaca caaggaacgg
     4561 cagaggagcc atttttatct caaattaatc aaagtattgc aagtcttgaa tcatctatcg
     4621 caagcctcaa aattcagcaa gctggtatcg gaagtgtagc aacttatgat aatagtttag
     4681 caaccaaaat tgaagtactc cgcactcagt ttttacaaac agcctcacag caacaactaa
     4741 ccgtggagaa tcaattaaca gaattaaaag tacaactaga tcaagcgaca cagcgcttag
     4801 aaaataatac cttaaccgct ccaagtaaag gtatcgttca tctgaacagc gaatttgaag
     4861 gtaaaaatag aattccaact ggtacagaaa ttgctcaaat attccctgtc atcacagata
     4921 caagagaagt actaatcact tactacgtat catctgacta tctcctctta ctagataaag
     4981 gacaaactgt aagattaaaa ctggagaaga ttggaaatca cggcaccacc atcatcggcc
     5041 aacttcagag tattgatcaa actcctacca gaacagagca aggcaatctc tttaaattaa
     5101 ccgctcttgc aaaactatct aacgaggata gtaaactcat ccaatatggc ttacaaggtc
     5161 gcgtcactag tgtaactaca aagaaaacat attttgatta tttcaaagat aaaattttaa
     5221 cacattctga ttaattttca gataacactc tataactatt tattatctta tcaaaaagga
     5281 gaatcataac atggataaga aacaaaacct aacttcattt caagaactaa caactaccga
     5341 actcaaccaa attataggtg gaggatggtg ggaagatttc ttatatagat ttaatataat
     5401 tgaacaaaaa aatacaaaag gatttcatca gccaatacaa ctataaaaaa acaagaccaa
     5461 gagaacgcac tctcggtctt attttttctt cattctatat gtattacagt aagtacctga
     5521 cgaaaaacgt gatcttggca ggtggtattg agactggtat tgggatgact ttccacaatt
     5581 ttcataacgg tatagagacc aactcctctc tcctcccctt tagaacttgc tccaaaggag
     5641 aagatttcag aaatatcgat tccctcttct ttgatggaat tttcaatgat aaaggtctcc
     5701 tgtgctccat tttttaaaaa ggcaattgaa acatgaggtt gacaggcttc tacactagct
     5761 tcaatagcgt tgtcacaaag gatagacaca acggttagaa aatcaagtag actcatcccc
     5821 tctacctgaa tctcctctgg aacttcgaca ttaaagacaa tgttcttatc tctagctttt
     5881 agaaatttcc ctgctaggag acttttgagg gctttatcac gaatattcac caatcgacca
     5941 aggtcatatt tattgtcctg caatttttca ctagaatcct ttaagaccga gtcgtagatc
     6001 tcttttatct gctccatatc ctcctcttca atgcccagac gtaagctagt caagaggttg
     6061 gtgtagtcat ggcgaaaact ccgtacttcc ttataaagct cctctatatg ccgactatac
     6121 cgctccatct ctctgtagcg caagtcctgc tcttggttca gtctctcatg gagtttgtcc
     6181 ttcaaatagg tatccaattt cttgataatc cccataaaaa agagcaggta aaagactagg
     6241 atgagatggc gaacagtcgt tgattgaatc ccctgttcat attcaaagta agacagattt
     6301 tgtatcacca aatagtaagc ccccattatc cagttaatct gagtcaggga cttttgaaaa
     6361 tctttatcga gaatcccctt tctcaagcta gtgaaatcat agtccaacca tttcaaaaaa
     6421 gctagagaaa tgaagaaatt gaaaattatt atacataacc aaataaatga gtagtcatca
     6481 tatacttgcc cttgtcccaa aaatggaagc acaaaatagg aaacacctct ataaaagaga
     6541 ttcactaata tcattggaaa gagaccataa aagagaagga gttttttagg aagttctctt
     6601 aacaataaga aagataagcc tatgccgtac aagggttcca taaaataaga tagataagta
     6661 tttcctacca tatagccaag cattccaaaa acaacggcca acagtatctt aaaaagaaag
     6721 gccttaaaaa tcctctcaaa agtgagacta attccatcta ccttaaagaa tatgacaatt
     6781 tttaatccgt gagtaacaag tgtatacaac aatatccaag caacattcat aaactctcct
     6841 agctcagtgt aagttattaa tagcctcaga cacttccctg accttataac gcgcgattag
     6901 acaacttcca ccattgggaa agaaaagcag tttttctttc ttatctaaat gcaccacatt
     6961 ggcaggattg atgagaaaag agcgatggca ctgcaagaga cgaggctcct gcttgagaac
     7021 ctcctctaga ctcgctgtaa attccagcct gtctgtcttg gtatagagaa taacacgatg
     7081 gggtcttgtg gacgtttcga gatagtaaac ctctttaaaa ggatactgga attgagcaaa
     7141 ttttgattta aagtaaaagc aatcttccgc tagactttta ctgtcttgac cattggcata
     7201 gaggagggct gtctcgatac gagattcaaa ctcctctgcc gaaagggcct tatcaatata
     7261 gtccagagca gacacttggt agcgaaagga caggggcata aactccgagt gagtcgtcac
     7321 aaagacaatc agggcatacg gatcccgatc ccgaatcttt ctagccactt ccagaccctt
     7381 catctcctca tttcgaatct caatatccaa aaagaatagc tgatgggccc ccttctcatg
     7441 cacctctgcc agcagttggt ctggcttgcc aaatacctca aaagagctgg gagtgatatg
     7501 atgttccttc aagagtttct caatcgtcgt ttcaatccta gtctgttggg aaaaatcatc
     7561 ctctaaaaca aatattctca tcttcttact ctccctcttt caaccatttt tgacgaattt
     7621 ctctatagcg acgtctggca tacttgacag cgtattgacc ttcttctccg agaaaaagga
     7681 ttctttcttg aaaatcaatc gattttaatt tatcaagatt aaccaaacaa tttcgatgac
     7741 atctcatcaa ggtttcccca tattggttct caagattact taaattttga agcatattaa
     7801 aactagcttc ttctgtaaca atctgtacgg tatgggcttt agttggatgt gtttggatat
     7861 agtagatatc gtcgacgttt actttataga ctgttttctg cgtctgaata atcatatgtt
     7921 tcattggatt ctcctcctaa gaaaagaata acagaaaagt tctagcccaa gcccacccaa
     7981 tcctaaacag tctttgaaag ctcctaaaag gattattttt ctacaacatc atgatgagct
     8041 tacaactatt ttatcataaa attcactcag cgcaattcaa gacatttcaa tgacaattaa
     8101 agatttgaat aaaaaaaaag aattaaaaat gataaactaa cagtatcaaa acacagttgc
     8161 cagaagtaag actggcaccc agattaaagg aggcattccc atgacagata cagaccccat
     8221 caaaagagct catactttga ttactgactt aaacaaagcc taccaagcat gcaaacaggc
     8281 aagcgctgac gacgtccgct ttcaggagca attaaactct attcttggtt ttttagccaa
     8341 ggctgaaaca gtggataatc gattcttgat tgaactagaa aaattttacc agacttccag
     8401 tcttctcatg ggactcagcg ctcttgatcc agatgctcca actcgcgccg cttggcgggc
     8461 ctatgaccgc ttccactttg accaagtcaa gaccaagtta atactcaatg aaaatcaaag
     8521 agcaaactag gaagctagcc gcaagctgta cttgagtacg gtaaggcgac gctgacgtgg
     8581 tttgaagaga ttttcgaaga gtataagtct ctacggacca accattatcc tgtagtaaca
     8641 aaaaagaagc tgagacagac tgaactcaac ttctttttta gtgtcgtatc agcaatgtta
     8701 gtcctgcatc tgacgtttta cctgataagg caaatacaag actagtaaaa ccaaaccagc
     8761 tcctagtaag gctagaaggg ccagtttttc ttggaaggta atcaacccaa caactaattc
     8821 cacaagtaaa acaaaactgg tcaatcctcg aactacctcc tgtaagcctt tttccttttg
     8881 ccccttgtcc agcggaaaga gttgggtcaa atactggtag tcaaaggcat gatagagggc
     8941 cagcaactgg aagagcaaga ggtagttaaa gagaactacc actgctgtcg caatccaagc
     9001 ttgctcgata aaaacctgcg ccagtacgga aagtaataga agacgaagac tgagagcaaa
     9061 gaggtcgcca tttcgcagat aagaacgcag atagagattt tgccaaatct tcccaggcac
     9121 cttctgaaca gcctttaaga taaagtccag ataggcacga cgcttaacgc tgtttgaaat
     9181 tcccttgacc tgcgtaaaga gggcaaagaa acgaagcaag acttgcttac gcttgctttc
     9241 ttgagaaata acatagtccc agtccagtcc agtttcagta aaaaatttgc tggccttttg
     9301 acgaaagtgg aaatattttc ctacccccaa taaaagcaca tatagcagaa aaactggcaa
     9361 gccataaccc attgctaaaa ataaaggcgc aaataacagc aagaaaaggg tctgtacaaa
     9421 gagccaaaag actagggaaa tgccagtttg acgcttgaga tggagcttga ttgcctcttc
     9481 tccaactaag agaaagagct tgtctggagc ctccatatag gtggcaattc ctccccaaag
     9541 taagagtaaa acagacgtaa ttcctacaaa caaaaggata ggccaatgat tttcaggaaa
     9601 atgttgtaag agttgactgt actggtaggc tagaaagccc aacaggacaa gcaggaacaa
     9661 gacaaagtgg tcattgagca catagcgcag ataacaaaga cactccttac gaaaggcctg
     9721 ctttctcttt aaaaacaagt ctttcataga tcctcctctt tggtcagagc caagtaaata
     9781 tcattcaaac tagcctcagg catatcaaag gcttcacgta gttgcaggag attgcctttg
     9841 gcacgcacct ctcccttgtg aagaatgaca aaggcatcac acatcttttc cgccgaatcc
     9901 agcacgtggg tactcatgag aatagacttg cccttttgct tctccacttc caaaagctga
     9961 atcaaatcag aaatagccag cggatcaaga ccaaggaaag gctcatccac gatgaaaaga
    10021 cttggatcca ccacaaaagc acagataatc atgaccttct gcttcatccc ttttgaaaaa
    10081 tgaacaggga accagtctaa tttctgttcc aaacggaaca tttttaacaa gggctctact
    10141 cgttcgaaag ccactttttg ctcaataccg taagccatag caaccgtttc gatatgctct
    10201 ctgagggtca attcctcata cagactaggc gtctcaggaa tgtagccaat ctgcttgcgg
    10261 tagctagtcg catctccttg cagagtcagg ccattgatat tgatggagcc actataaggt
    10321 gccaacagac cgataatctc attgatcgtc gttgatttcc cagcaccatt gagaccaatc
    10381 aaaccgacca actgcccact ttcaacagta aaggacacat ctttcaaaac aggaacatga
    10441 acatagccac ctgtcaggtt tttaatttct aacatatttt ctccaaatct ggtataatgt
    10501 agctatatta tatcaaaatt cagtacagta gaggtagatt ttatgtcaga ttgcattttt
    10561 tgtaaaatca tcgcagggga aattcctgct tcaaaagtat atgaagatga gcaggtcctt
    10621 gcctttcttg atatctctca agtaacacta ggacacacct tggtcgtgcc aaaagaacac
    10681 tatcgcaatc ttttggagat gaatgctacg agcgccagcc aactctttgc ccaagtacca
    10741 aaagtagctc aaaaagtcat gaaagtcact aaggctgctg gtatgaatat catttccaac
    10801 tgtgaagaag tcgctggtca aacagttttt catactcacg ttcaccttgt gcctcgctac
    10861 agtgctgacg atgacctcaa gattgatttt atcgcccacg aaccagactt tgacaaactt
    10921 gctcaagtcg ctgaaaccat caaaaacgct taaggagttg ctatgaaatt atccaaccta
    10981 ctgctatttg caggagctgc agccggaagt tatctggtta caaaaaatcg ccaaaccatc
    11041 acagatgaag tcttgaatac cactgaccgc gttcaagcta tcaaagacga tgtggatatt
    11101 atccaaaata gcctgcaaat catcgaccag caaaaagaac ttatcaagga ataccaagaa
    11161 gacttgactt acaagtttaa ggtcttggaa aaggatatcc agactagact agctgtgata
    11221 aaagaaatgc agggaactga agataagtaa aaagagcccc ccggctcttt tttaaaacgt
    11281 aaacaagtta tagtgaattg aatttagaat agcacatcat agtttctaaa gcattgttag
    11341 agattacttt aaaatcctct tatcaatttg ttcatattct atttcaatct actatatata
    11401 tcccatcaac tatgcatcat aatttaggta actcatactc aataaaaatc aaaaagcaaa
    11461 ctagaaagct aggcacagac tgctcaaaac accgttttaa ggttgtggat agaactgacg
    11521 aagtcagctc aaaacactgt tttgaggttg tggatagaac tgacgaagtc agtaaccata
    11581 cccatgacaa gccgacgctg acgtggtttg aagaaatttt tgaagagtat cattcaccat
    11641 ttcacaacta aatcgaagac tttctgccgt aatgaaaaca cctgaaacag cttggtttca
    11701 gctgtccgga aactttaaga cttaggttca aagtttaggt atggaacttc gaaggaggtc
    11761 gctaccgtcc gtcattactt aggaaagtct taaaaaatct ataaagtaaa aagagcccga
    11821 cagctctttt tgtttatact caatgaaaat caaaaagcaa actaggaaac tagccacggg
    11881 ctgctcaaaa cactgttttg aggttgtaga tacgactcac atatatacgg caagccgacg
    11941 ctgacgtggt ttgaagagat tttcgacgct gacgtggttt gaagagattt tcaaagagta
    12001 ttattctcca tcaaaggcat ctttaatatg gtcaaagaag ccttttttct ttggatttac
    12061 tttcaagtca ccagcagccg cgaattcttt caaggctact ttttggcggt cgttcaagcc
    12121 tgtcggtgtt acgacattaa cagtaacgta ttggtcacca actgcaccgc cacgaaggct
    12181 cggtgccccc ttactacgta ggcggaattt cttaccagtc tgagttccct ctggaataac
    12241 caattcaaca tcaccgtgaa cagttggaat atctactgta tcaccaagag ccgcttggac
    12301 aaagttgagg ttgagattgt agaagatagt cgttccttca cgttcaaact tgtcgctagc
    12361 ttctacagaa actactacat acaagtcccc ataaggtcca ccgttaaagc ctgcttcgcc
    12421 ttgaccagcg aggcgaattt gttgacctgt ttccacacca gcagggattt tcacatgtac
    12481 gctatgagct tgtttctcat gacctgttcc atgacaggtt gtacatggat atttgatttc
    12541 ttttcctcga ccgtgacaga catcacaggt tacttggcga cgcatcatac caagaggagt
    12601 ctgcgtatcg acgttaatga caccagcgcc atgacagcgt ccacaagtga ctggacttgt
    12661 ccctggctta gcaccagagc cattacatgt acgacagcca gcttcacgat gatacttaac
    12721 ttccttctca gttccgaaga tagcttcttc aaaggtcaaa ttgacacgat actggagatc
    12781 atctccttgg cgaggagcgt ttggattgcg cgaagaaccg cctccgccga agaaacttga
    12841 aaaaatatcc tcaaaaccac cgaagccacc tgccccattg aaaccaccga aaccaccagc
    12901 tccaccaaaa ccaccattgg cgcctgcagc accatactgg tcataggcag cacgtttttg
    12961 gtcgtcactc aaagtctcat aggcttcttg aacttccttg tacttgtcct cagcaccagg
    13021 ctccttgttg atatctgggt gatatttttt ggaaagctta cgataagcct ttttgatctc
    13081 gtctgccgaa gcgttttttg acacccccag acgatcataa aattcagtat tgttcataca
    13141 agataccaag accgtaaaat tcgactgaaa aataggaaat ctgacgctgg agcgacgctc
    13201 ctagacagat ttctcttttt tccgagaatt taggtcgggt tcaattcctt tcttttatat
    13261 tgatgagata atactccagc cactcggccc tatccctttt taccgaaaaa cagaggctga
    13321 gttgcaacct ctgtggttag attattcatt tgaaataaaa atggttgtat tatctctagt
    13381 agtaatcttc aaagaccttt tagctaaatc aaactcaaat ttattatagt gtgggtcttg
    13441 tgttttatat aggtgtaact cctgacatat atgatccgaa aagtaaatca taacatcttt
    13501 aaacacagaa gtgtggtcat atttactctt accaacagct acttctgtaa attctttata
    13561 aatgacattt ccatttcttt ccacagtcac cagcatttct gttggattat aatccaaatt
    13621 aaataattct tcaaaaaact ttatcttttc atgataatct gcaatgtcag aaagattatt
    13681 tttattaaca ctcataacac tagcccctta tttttcagta aactctccgt ctacgacgtc
    13741 atcgcctgcg tttcctgttg cttgtgcgcc ttctgctcct tcttgagctt gttgcgctgc
    13801 tgcagcttgt tcgtagagtt taacagcaag tccttgagct ttttcgttca atgcttcaag
    13861 ttttgctttc atgtcgtcca agttgttgtc ttcttgagct ttcttaaggt catcaagggc
    13921 agcttgggca gcgtcacgtt ctgcgtcgaa gcctttacct tcagtttcct tgattgtctt
    13981 ttcagtcgca aagattgctt ggtctacttc attacgaagg tctacttctt ctttacgttt
    14041 cttatcggct tcagcgtttg cttctgcatc tttcatcatg cggtcgattt cttcgtcagt
    14101 caaacctgag ttcgattgga tgacaatagt ttgttctttt tgagttccaa ggtctttggc
    14161 cttaacagac acgataccgt tcttgtcgat gtcaaatgtt acttcgattt gaggaattcc
    14221 acgaggtgca gctgggatat cagtcaattg gaagcgtcca agagtcttgt tatctgctgc
    14281 cattgggcgt tcaccttgaa gaacgtggat atcaacggct ggttggttgt ctgctgctgt
    14341 tgagaagact tgtgatttag atgttgggat tgtagtgttg cgatcgataa gttttgtaaa
    14401 tactccaccc attgtttcga taccaagtga caatggcgtt acatcaagaa ggacaacgtc
    14461 cttgacatca ccagtaatca caccaccttg gatagccgca cccatagcaa ctacttcatc
    14521 agggtttact gatttgtttg gttctttacc agtttcagct ttaacagctt caacaacggc
    14581 agggatacga gttgaaccac caacaaggat aacttcgtcg atttctgaca agctcaaacc
    14641 tgcatctgaa agggcttgac gaactggaac ttttgtacgt tcaacaaggt cacgagtcaa
    14701 atcgtcaaat ttcgcacgag tcaaagtcat ttccaagtga agaggtccag cctcacctgc
    14761 agtgataaat ggcaagctga tttgtgttga agttacacca gaaaggtctt tcttcgcttt
    14821 ttcagccgca tctttcaaac gttgcattgc catcttgtca gtagacaagt cgataccgtt
    14881 ttctttcttg aattctgcta ccaagtggtc aatgattttt tggtcaaagt cgtcaccacc
    14941 aagtttgttg tcccctgcag ttgacaatac gtcgaagaca ccgtcaccca attcaaggat
    15001 agagacgtcg aatgtaccac caccaaggtc aaataccaag attttttctt ctttgtcagt
    15061 cttgtccaaa ccataagcaa gagctgctgc agttggttcg ttaacaatac gttctacttc
    15121 aagaccagca attttaccag cgtcttttgt tgcttgacgt tgagcgtcgt tgaagtaagc
    15181 cggaactgtg ataacagctt tggttacttt ctcaccaagg tagtcttcag cgtagccttt
    15241 caagtattga aggatcatag ctgagatttc ttgtggagtg tattcttttc catttgcaga
    15301 aactttttca gaagttccca tcttagattt gatagagata actgtatctg ggtttgtaac
    15361 tgcttgacgt tttgcagcat caccaacgat gatttctccg tttttgaatg agactacaga
    15421 tggagttgtg cggtttcctt ctgggtttgc gatgattttg ctttcagttc cttcaagaac
    15481 tgcaactgct gagtttgttg tacctaagtc aataccgata attttagaca tgtgtttttc
    15541 tccttgttag ttaattttct atttttcttt ttgatactct tcttaagtgg cgacgccgtc
    15601 agagcttgac ttcgtcaatc tctttgacta aactttgagc ctaaggtctc aaaatttgcg
    15661 caaatagcac cacggcgaag agtatcgtct ttggttcgct tcgctcacta ttacaaagcc
    15721 aaacatattt tatctttctt catagtttat tgtcgtttcg gacaagtttt ctattatgta
    15781 aattgcgaca cgaggagtcg aaatcgattt tatttcgacg acgagttagt aaggaagcta
    15841 ggcaaacgtc atagcgattg ccgttttctg acgagttgct ttagctaccg tcagaattgc
    15901 cgaatcgaac acgccctaag ctctgagtaa aaaagataga ttttcttgtg ttcatcgaac
    15961 acttcgtcaa tctcctattt ttactgcgag ctttttacga gctttgtatc ttagttatac
    16021 accactacca ttgctgggcg taggatgcgg tcatggagtt tgtagccttt ttgaaagact
    16081 tgggcgatgg tatctactgg gtgttcatcg tctgctggga gagtttggat ggccatatgg
    16141 tagttatggt caaattcgcc atctgctgcg atttcttcaa ttccttcttc tttcaaagcg
    16201 tgaatcaagc tttcttgcac catccccaag cccttcttca catcatctgt caaaccttca
    16261 actgcaagtg cacgctcaag gttgtcaaga gatggtaaga ttgcttttgc caagtcctgg
    16321 ctacgataac gttgcaagtt ttgacgttct tcattggcac ggcgttggat attttgcatt
    16381 tctgcatgag cgcgaagata tttgttttcg aactcatctg cacgttcatt tgccaagtcc
    16441 aactcagact tttcaggagt tgtttcttca gctgtttcca caacttcctc ttcttgaact
    16501 tcttctactt cttcattttt tatatcttgg gccatgttcg cctcctttaa tgatttcaat
    16561 cttaatgtac ttcgtaatga ttactgctga ggtagcggta aaaatctgtc aacttcatgg
    16621 tcaaaacacg gttgaccaca ttgacttgat tgattagctg ttggtaatcc agattaactg
    16681 gaccgataat ggctagaatt ccaactcccc gataaggaat gaggaactta ctactaatca
    16741 ccgctaggtc agctaaacag gactcttgac cgtctgcaac acgaacattt tgcatctgat
    16801 cctcacgcaa cccctcacga atctccaagg ccaccttttg cggttggtca aagaactgat
    16861 aggcttctag attggcaaaa ttcaagagat tgaccttgcc cgccatcaca atgttttcgt
    16921 tgaacatttc cttaaagatg tgttcaaaga gatcgatgac attatccgtt gttgtaaagt
    16981 aacgctggat aatctgcgga atctccgtcc gaatcttgta gtgaatatct aaaacggtgt
    17041 gaccgaggaa acgttcctga atgatgctct tcagtttcag caaatcctcc tgcaagaagt
    17101 tccttggaat cagaaactga ctagtaaccg ttcgcgactc gtctagggta aataccgcca
    17161 aggctgtatg ttgccccaaa acaacgatat caaaggctgt caaacgttgc ctgctcggct
    17221 caacatccag tgccactacc gtacagccac tcaggcctgt tagcaagtta gcagcctctt
    17281 gcagaatatc ctccaatttg aagaattcct gatcaaaggc tttgacaatc tcatatacct
    17341 cattttcagc cagccggtga aaatccagtg agtgtttcac atagtactga aaaccagcaa
    17401 cacttggcat ccgaccgctt gaagtatgag ccttctcaag caacccttgt ttttctagtt
    17461 ccgccatgtc attacgaatg gttgcactgc tagagttaat agactcttgc aaggcttttg
    17521 atccgacagg ttcgtgcgtt ttggtaaaga tgtcaataat cagatttaaa atatcctgct
    17581 gacgctctgt aaccatctca tcactcctct ctgtctgatc aattagcact caatgcatcc
    17641 aagtgctaac ttatgattct attatacacc cttaaaagag aatgtcaaga caaaaactca
    17701 aaaaattagc actcttttat caagagtgct aaaaatcaat ctgaagacct agaaccttgc
    17761 tattcatcta ctcggtattt cctttttagt ctgaaataac catgaattag ataagaaatc
    17821 agaaaagcat ataaaacaaa aataagaaag aaagacatag aaagatcctc tctaaacaaa
    17881 ctcgtacaaa caacaagacc acctaagaaa gtagttgtac aggaacgaag tctagatcgc
    17941 ataacttccc atttgagccc cttactcata tagacttgat cctctggaag taaatcagaa
    18001 gacgatttac gaagaatcga acaagaacct gctcctatca attcccaacc tctatctcta
    18061 aaatcttgca gttcatgctt atatttttta agaaatctag aatcatagat acggtagatg
    18121 acatcgtctg gttgacattg gtcaaaatag aacaaaccaa aacgactcgt tctatacctc
    18181 caacctttca aatgcatctc atgtaaatat tcttcttcct tgtccaaatc aacaatggtg
    18241 aaaatccgaa attctactct gctattcatt gtcttacccc aaaattagaa aacatgcctg
    18301 gcgttattta ttagataatt ctttccactt ttgactcaat ctccaaaaaa tataagaaat
    18361 ctgaatcgca aaaactatca ataaaaccca atctattatg aaaatcaaaa acactttcca
    18421 actgaaagaa ctacctccag tgacaaactt tgagcaaaac ggtagtagag ctaaaaagag
    18481 aagtaaaata ggaagcatcc gcattgttaa aatccgtttg gcataaaaaa atctttattt
    18541 aaactaaaat attatagcaa aatttacgcc agtttttgaa cggctgatgt agatatttta
    18601 tactttcaaa atgtttaaat gtgattattt atttttgaaa aatagctcac cagcccgact
    18661 gaaagtgctt atagaatgat aataagtcgc ctgccgaaaa cagcggaaaa tagcggtgtt
    18721 atgcggagat aatctgacgc gatgcgaaag tatattgcat acttattttc aacaatttag
    18781 cagagtattt ttataagtgt gatataatag aagtataatt tgttctgata gtttatttta
    18841 tggagaagta gatttttaga atgcggaggg ttcaatatgg ttgagtttat aaagtctaag
    18901 aaagaaatga gtgaggagga tattaaagca aatttcatca ctcctgctat tgtatccaaa
    18961 ggatggaaaa atggtgagca tatcgcttac gaagaatact tcactgatgg tcgaattgag
    19021 gttagaggag ataaggctcg tcgtaaagaa ggaaaaaaat cagactattc actgtattac
    19081 caatttggaa ctcgaattgc aattgttgag gcaaaggata ataaacacag cgttcgagca
    19141 ggattacaac aagctattga atatggagag attttagatg ttccatttgt ttattcttcg
    19201 aatggtgatg gctttattga acacgaccgt atcacgagag aagaacgtga gctggagtta
    19261 gacgaattcc ctactcgtga agaattattt tctcgtatga cgaaggaaaa aggattgacg
    19321 tacgaaatta cagaagctat ctcaactcca tactatacag acgccttctc aatgaaaacg
    19381 ccacgctatt atcagcaaat agctatcaac cgtactattg aaacagttgc cagaggacaa
    19441 aaacgagtaa tgtttgtgat ggcaacagga acagggaaaa cgttcatggc ttttcaaatt
    19501 attcatcgcc ttcgaaaagc tggtttggct aaacgagttt tattcttagc agatagaaac
    19561 atcttagtag accaaacgat ggctgaagac tttaagccat tcgaaaaggt aatgacgaaa
    19621 attacaccaa aacttttgac tgctcctgaa aaattaaatt ctttcgaaat ttatctaggg
    19681 ctttatcagc aactaactgg tgaagatgga actgaaacac attatcaaaa atttgacaaa
    19741 gacttctttg atttaatcgt aattgatgaa gcgcaccgtg gttcagctaa ggaaaacagt
    19801 aactggcgta aggtaattga ttatttcagt tctgcgacac agattgggat gaccgctact
    19861 cctaaagaaa ccaagaatgc ttccaatacg gaatactttg gtaagccaat ctatacttat
    19921 agtttaaaac agggaatcga ggatggtttt ttggctccat atcgtgttat gagggttaat
    19981 ttagatgtgg atgtggatgg ttatcgtcca gaaactggaa aagttgatgc taacggacaa
    20041 ttaatagaag ataggtacta cggcaggaaa gattttgata aaaccattgt cattgatgat
    20101 agaacgcaaa gagttgccaa gtttgtttct gattatatga agcaaaacaa tgcacgattt
    20161 gataaaacaa ttgttttttg tgttgatatt gaccatgccg agcgaatgcg tgctgcactt
    20221 gtaaaagaga atctagactt agtccaagaa gactatcgtt atgtcatgca agtaactggt
    20281 gacaacgctg aaggaaaagc tcaactggat aactttatgg atgtcaattc taattttccc
    20341 gctattgtaa caacgtctaa attattaacg acaggagtta atgctaaaac atgtcgtttg
    20401 attgttttag actctaatat ccaatccatg actgaattta aacaaattat tggtcgtggc
    20461 acacgtcttt atcctcaaaa ggggaaagaa ttttttacga ttattgattt tcgaaatgtt
    20521 accaatttgt ttgctgaccc tgattttgat ggtgagccag tgaaggtgct ggaaacaggt
    20581 gcgaaaacag tcagtggttc tacgcctggt ttcgtaggtg aggaaggtga cccagtagaa
    20641 aaatatatcg ttacagacaa gcaggttacc attcttaatt ctactgttca agtattggat
    20701 gaaaacggga aactgattac cgaaagcctg accgactaca ctcgaaagaa tatcttaggt
    20761 agctacgcca ctttgaacga ttttatcaca gtttggcata cggcagataa gaaacattat
    20821 gggaagtttg ctgatggaag cactcaagaa attgatgttc cttatgatat tcctgatact
    20881 tgggagtggg tgaggttttc tacattggtt gaaattgtca gaggtggctc tccacgacca
    20941 atcaaagatt atcttacttc tgaagtagat ggaataaatt ggataaaaat aggtgatact
    21001 gaaaagggtg aaaagtatat aaataatgtt aaagaaaaaa tcaaaaaatc agggcttaac
    21061 aaaactagat ttgtaaaaaa aggtacattt ttgttaacta attctatgag ttttggtaga
    21121 ccttatattt tgaatgttga tggtgcaata cacgatggat ggttggctat ttcgaactat
    21181 gaaaactcat taaataaaga ttacctattc tatattcttt catcaaatgt agtttattct
    21241 caatttctat ctctaattag tggagctgtt gtgaaaaact tgaatagtga taaagttgct
    21301 tctattctta tc
//
LOCUS       DAVBCA010000035        21306 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.035, whole genome shotgun sequence.
ACCESSION   DAVBCA010000035 DAVBCA010000000
VERSION     DAVBCA010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21306)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21306)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21306
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.035"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            36..380
                     /locus_tag="VQU19_001277"
     CDS             36..380
                     /locus_tag="VQU19_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002202361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2480524.1"
                     /translation="MIAHTIHQKFNLKVPNYRQEEDWARMGLPIIRKEISNWHIKTSQ
                     YYLEPLYNLLRERLLTQPLLHADETSYRVLESDSQLTYYWTFLSGKAEKQGITLYHHV
                     LIDLFISYFNPL"
     gene            complement(577..1497)
                     /gene="cysK"
                     /locus_tag="VQU19_001278"
     CDS             complement(577..1497)
                     /gene="cysK"
                     /locus_tag="VQU19_001278"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HET2480525.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKLGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(1782..2417)
                     /locus_tag="VQU19_001279"
     CDS             complement(1782..2417)
                     /locus_tag="VQU19_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HET2480526.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVSVNLV"
     gene            2473..3771
                     /locus_tag="VQU19_001280"
     CDS             2473..3771
                     /locus_tag="VQU19_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET2480527.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPTL
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLSLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLEEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVIEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            3768..4430
                     /locus_tag="VQU19_001281"
     CDS             3768..4430
                     /locus_tag="VQU19_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HET2480528.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQACQFWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            4510..5058
                     /gene="raiA"
                     /locus_tag="VQU19_001282"
     CDS             4510..5058
                     /gene="raiA"
                     /locus_tag="VQU19_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HET2480529.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNIVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            5194..7167
                     /locus_tag="VQU19_001283"
     CDS             5194..7167
                     /locus_tag="VQU19_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HET2480530.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTALLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDALGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNTVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGRKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            7164..7616
                     /gene="rplI"
                     /locus_tag="VQU19_001284"
     CDS             7164..7616
                     /gene="rplI"
                     /locus_tag="VQU19_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HET2480531.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            7660..9012
                     /gene="dnaB"
                     /locus_tag="VQU19_001285"
     CDS             7660..9012
                     /gene="dnaB"
                     /locus_tag="VQU19_001285"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HET2480532.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            9014..9280
                     /locus_tag="VQU19_001286"
     CDS             9014..9280
                     /locus_tag="VQU19_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480533.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            9369..10715
                     /gene="cbpD"
                     /locus_tag="VQU19_001287"
     CDS             9369..10715
                     /gene="cbpD"
                     /locus_tag="VQU19_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HET2480534.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRV
                     IKANTMTGFIHFKDLDGGSVGNSQSSTSTGGTHYFKTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKTKSA
                     IKTEPLVSGTVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     regulatory      10798..10900
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            10971..11261
                     /locus_tag="VQU19_001288"
     CDS             10971..11261
                     /locus_tag="VQU19_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HET2480535.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     gene            11224..11982
                     /locus_tag="VQU19_001289"
     CDS             11224..11982
                     /locus_tag="VQU19_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2480536.1"
                     /translation="MRNLKSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     NPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRT"
     gene            12020..13027
                     /locus_tag="VQU19_001290"
     CDS             12020..13027
                     /locus_tag="VQU19_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET2480537.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            13027..13755
                     /locus_tag="VQU19_001291"
     CDS             13027..13755
                     /locus_tag="VQU19_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2480538.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            13874..14332
                     /locus_tag="VQU19_001292"
     CDS             13874..14332
                     /locus_tag="VQU19_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HET2480539.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQVIQEVDRKGK"
     gene            14334..16766
                     /locus_tag="VQU19_001293"
     CDS             14334..16766
                     /locus_tag="VQU19_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET2480540.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFMELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALVLGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     ALRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKVKYVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            17408..18061
                     /gene="rr06"
                     /locus_tag="VQU19_001294"
     CDS             17408..18061
                     /gene="rr06"
                     /locus_tag="VQU19_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HET2480541.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDIWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            18058..19398
                     /gene="hk06"
                     /locus_tag="VQU19_001295"
     CDS             18058..19398
                     /gene="hk06"
                     /locus_tag="VQU19_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HET2480542.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILFLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGEVGKQINGMYEHLLKV
                     IHELESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIA
                     KSINKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIEN
                     QLTDATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQE
                     LEHLFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            19481..20008
                     /locus_tag="VQU19_001296"
     CDS             19481..20008
                     /locus_tag="VQU19_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HET2480543.1"
                     /translation="MVLAIILVTFFIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCLVEAMVHKTIFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYVTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            20087..>21306
                     /locus_tag="VQU19_001297"
     CDS             20087..>21306
                     /locus_tag="VQU19_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RICH domain-containing protein"
                     /protein_id="HET2480544.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVVVASLFLGGVVHAEGVRSGD
                     TPKVTSSGDEVESHLKKILSEIQTQLDRKRHAKTVALINKLQDIKRTYSYKLNVLEEK
                     PKAELTSKTKEELTAAFEQFKKDTLPTEPGKKVAEAEKKVAEAEKKAEDQKEEDRRNY
                     PTNTYKTLELEIAEFDVKVKEAELELLKEKAKKPLNEGTIKQAKEKVESKKAEATRLE
                     NIKTDRKKAEEEAKRKAAEEDKVKEKPAEQPQPAPAPQPEKPAPKPEKPAPAPKPENP
                     APKPEKPAPAPKPENPAEQPKAEKPADQQAEEDYARRSEEEYNRLTQQQPPKTEKPAQ
                     PSTPKTGWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNSNGAMATGWLQNNGSWYYL
                     NANGSMATGWLQNNG"
BASE COUNT         6687 a         3544 c         4808 g         6267 t
ORIGIN      
        1 aagccccttt agcgcataac tttggctcag cttctattat cgctcacacc atccatcaga
       61 agtttaatct gaaggtaccc aattatcgcc aagaagaaga ttgggctagg atgggtttac
      121 caatcatacg taaggaaatc tctaattggc atatcaagac gagtcaatac tatttggagc
      181 ccctttataa cctcttgcga gagagactat tgactcagcc cttacttcat gcggatgaaa
      241 cttcttatag ggtgctagag agtgatagtc agctgactta ctactggact tttttgtctg
      301 ggaaagctga gaaacaaggg attacgcttt accatcatgt cctaatcgat ttgttcatat
      361 cttatttcaa tccattataa atagtgagaa atatctatcc tatcttctag aatgtcttcc
      421 aaacgtggaa actctcgtaa acaaagaggt tttagaggcc tatttaccat ggactaaagt
      481 tgtacaagaa aagtgcaaat aagaaatctc cagattagga actatccgtg agttctctag
      541 tctggagatt tttcaataga cttcgttatt ggacggttac aattcataaa gtgctgtaga
      601 gagataacgt tcaccgttat ctggtgctag ggcaaggact tttttacctg tacctaattt
      661 tttggcaacc tcgatggctc cgtagatagc tgcagctgag gaaatcccta caaggaagcc
      721 ttcttttcca ccaatttcac gtccgagtgc aagagcgtca tctgatgtta cacgaacgat
      781 accatcatag gctttagtat caagtgtatc aggaataaat ccagctgaga taccttgaat
      841 tttgtgagga ccaggttttt caccagatag aatagcagat tcatctgctt ctactgcaaa
      901 aacttgaatg ttagaatttt ctgatttgag tgcatgagaa acaccagaaa tcgttccacc
      961 agtacctact ccagcaacaa aggcatctaa tccatcttta ccgaaagcag ctagtatctc
     1021 agctcctgtt gttctttcgt gtacttctgg attagctgga ttgtcaaatt gaagaggaag
     1081 gaaaccatca cgttcagcag cgatttcttg agccttagca atagcacctt tcattccctc
     1141 gctaccagga gttaggacga gttcagcacc ataagcttgg ataattttac gtcgttctac
     1201 actcatagtt tcaggcataa cgatgacgac tttataccct ttagcagcac ctacccatga
     1261 aagtccaata ccggtgtttc cacttgttgc ttcaacaata gtagaaccaa gtttcagaat
     1321 accatcttgt tcagcttttt caatcatgct aagggcaata cggtctttta cagatgaacc
     1381 aggattaaat gcttcaagct ttatatagac gtctgcagca ccttctggca cgatgttgtt
     1441 aagtttaaca atcggtgttt gaccgattaa ttcagtaatg ttgttataaa tagacatatg
     1501 aatacctctt tgtataagat atctttagta taacgctatc cataccattt gtaaaatata
     1561 gaaatcctat cgaagcgata ggatttctat atatcataga tcaaagtcat taattttcaa
     1621 gtgattgcgt tcagttaatt ctagtaaata ggtgtgaagg aaaacgatat caggtttcgt
     1681 ttgaattgct tcattttcta gtatattttg gtacgcatct ttttattttg ctcgctaaag
     1741 tagttgtgag aatgtcaacg aaacgctgta ttattcattg tttacactaa gtttacagaa
     1801 acttcaacct ctcgtaaacc ttggtcagtt aaagtgactt ttccattaaa aaactccaca
     1861 agtgcagctt taatagtttc tttttcttct ttatcaacat aaatcatcgt atcgacttga
     1921 tctgtaaagt ttgtatccag ctccatgaga tcatgttctt taaggaagtt actgtactct
     1981 tggtactgag cataagacat ttgaatagca atgccagcct gttcttttat ttcaataata
     2041 ccaatttctt tgacagctaa ggcgacactg ccggcgtaag cacgaattag tcctccagcg
     2101 cctagtttaa taccaccaaa gtagcgtgtc acgaccacac agacattggt gagattgtga
     2161 ttttctagta ccccaagcat gggaacacca gcagtaccac taggctcacc atcatcactt
     2221 gtacgtttaa tttcactacg ttctccaata ataaaggcag agcagttatg tgtcgctttg
     2281 tagtgttctt ttttgatggc agtaatgaag tcacgagcct cttcttcgct ataaacacgc
     2341 ttggcatggc agataaagcg agattttttg atttcttctt ggacttggcc gtcctcttta
     2401 attgtcctaa attccatgat ttaattgtac taaaaaataa tctaaagtgc tagtttttac
     2461 gaataaagaa gtatgaaagt aaatttagat tatctcggtc gtttatttac tgagaatgaa
     2521 ttaacagaag aagaacgtca gttggcggag aaacttccag caatgagaaa ggagaagggg
     2581 aaacttttct gtcaacgttg taatagtact attctagaag aatggtattt gcccatcggt
     2641 gcttactatt gtcgagagtg cttgctgatg aagcgagtca gaagtgatca aactttatac
     2701 tattttccgc aggaggattt tccgaagcaa gatgttctca aatggcgcgg ccaattaact
     2761 ccttttcaag agaaggtgtc agagggactg cttcaagcag tagacaagca aaagccaacc
     2821 ttagttcatg cggtaacagg agctggaaag acagaaatga tttatcaagt agtggctaaa
     2881 gtgatcaatg cgggtggtgc agtgtgtttg gctagtcctc gcatagatgt ttgtttggag
     2941 ctgtacaagc gcctgcaaca ggatttttct tgcggtatag ctttgctaca tggagaatcg
     3001 gaaccttatt ttcgaacacc actagttgtt gcaacaaccc atcagttatt gaagttttat
     3061 caagcttttg atttgctgat agtggatgaa gtagatgctt ttccttatgt tgataatccc
     3121 acgctttacc acgctgtcaa gaatagtgta aaggagaatg gattgagaat ctttttaaca
     3181 gcgacttcga ccaatgagtt agataaaaag gtccgtttag gagaactaaa aagactgagt
     3241 ttaccgagac ggtttcatgg aaatccgttg attattccaa aaccaatttg gttatcggat
     3301 tttaatcgct acttagacaa gaatcgtttg tcaccaaagt taaagtccta tattgagaag
     3361 cagagaaaga cagcttatcc gttactcatt tttgcttcag aaattaagaa aggggagcag
     3421 ttagaagaaa tcttacagga gcaatttcca aatgagaaaa ttggctttgt atcttctgta
     3481 acagaggatc gattagagca agtacaagct tttcgagatg gagaactgac aatacttatc
     3541 agtacgacaa tcttggagcg tggagttacc ttcccttgtg tggatgtttt cgtaatagag
     3601 gccaatcatc gtttgtttac caagtctagt ttgattcaga ttggtggacg agttggacga
     3661 agcatggata gaccgacagg agatttgctt ttcttccatg atgggttaaa tgcttcaatc
     3721 aagaaggcga ttaaggaaat tcagatgatg aataaggagg ctggtctatg aagtgcttgt
     3781 tatgtgggca gactatgaag actgttttaa cttttagtag tctcttactt ctgaggaatg
     3841 atgactcttg tctttgttca gactgtgatt ctacttttga aagaattggg gaagagaact
     3901 gtccaaattg tatgaaaaca gagttgtcaa caaagtgtca agcttgtcaa ttttggtgta
     3961 aagaaggagt tgaagtcagt catagagcga tttttactta caatcaagct atgaaggatt
     4021 ttttcagtcg gtataagttt gatggagact tcctgttaag aaaagttttc gcttcatttt
     4081 taagtgagga gttgaaaaag tacaaagagt atcaatttgt tgtaattccc ctaagtcctg
     4141 atagatatgc taacagagga tttaatcagg ttgagggctt ggtagaggca gcaggctttg
     4201 agtatctaga tttattagag aaaagagaag agagagccag ttcttctaaa aatcgttcag
     4261 agcgcttggg gacagaactt cctttcttta ttaaaagtgg agtcactatt cctaaaaaaa
     4321 tcctacttat agatgatatc tatactacag gagcaactat aaatcgtgtt aagaaactgt
     4381 tggaagaagc tggtgctaag gatgtaaaaa cattttccct tgtaagatga ggaaaaaatt
     4441 tgcaaaaata gaatgaaagc gttataataa aatcataaaa acaaaaatgt ttagaaagaa
     4501 ggtactcata tgattaaata tagtatccgt ggtgaaaacc tagaagtaac agaagcaatt
     4561 cgtgattatg tagtttctaa actcgaaaag atcgaaaagt acttccaacc agaacaagag
     4621 ttggatgccc gaattaactt aaaagtttat cgtgaaaaaa cggctaaagt ggaagtaacg
     4681 attccgcttg gatctattac tctccgcgca gaagatgtat ctcaagatat gtatggttca
     4741 attgaccttg taactgataa aattgaacgt cagattcgta aaaataaaac aaaaatcgag
     4801 cgtaaaaata aaaataaggt agcaactggt caattattta cagatgcttt ggtggaagat
     4861 tcaaatattg tccagtctaa agttgttcgt tcaaaacaaa ttgatttaaa accaatggat
     4921 ttggaagaag caattctaca aatggattta ttggggcatg atttctttat ctatgtggat
     4981 gttgaagatc agacaaccaa tgtgatttat cgtcgtgagg atggcgaaat tggtttgtta
     5041 gaggttaaag aatcttaatt tcaatatgtg taaaggtagg tttactgaat tgtaaactac
     5101 ctttttctta taattgatag aattactgat tacactttta aaaagtcgct ttttgagggg
     5161 tattatggta taatgggtgc caagaggttt tgaatgaaaa aattttatgt aagtccaatt
     5221 tttcctattc tagtaggatt gattgcgttt ggagtcttat ccactttcat tatttttgtt
     5281 aataataatc tgttgacggt tttaattttg tttctttttg taggaggcta tgttttttta
     5341 tttaagaaac tgagagtgca ttatacaagg agtgatgtag aacagataca gtatgtaaac
     5401 caccaagcgg aagaaagttt gacagctcta ttggaacaga tgcctgtagg tgttatgaaa
     5461 ttgaatttat cttctggaga ggttgagtgg tttaatccct atgctgaatt gattttgacc
     5521 aaggaagatg gtgattttga tttagaagct gttcaaacga ttatcaaggc ttcagtagga
     5581 aatccgtcta cttatgccaa gcttggtgag aagcgttatg ctgttcatat ggatgcttct
     5641 tccggtgttt tgtattttgt agatgtatcc agggaacaag ccataacaga tgaattggta
     5701 acaagtcgac cagtgattgg gattgtctct gtggataatt atgatgattt ggaggatgca
     5761 acttctgagt cagatattag tcaaatcaat agttttgtag ctaattttat atcagagttt
     5821 tcagaaaaat acatgatgtt ttctcgtcgg gtaagtatgg atcgatttta tctatttact
     5881 gactacacgg tgcttgaggg cttgatgaat gataaatttt ctgttattga tgctttcaga
     5941 gaagagtcga aacagagaca gttgcccttg accttaagta tgggattttc ttatggcgat
     6001 ggaaatcatg atgagatagg gaaagttgct ttgctcaatt tgaacttggc tgaagtacgt
     6061 ggtggcgacc aggtggttgt taaggaaaac gacgaaacga aaaatccagt ttattttggt
     6121 ggtgggtctg ctgcttcaat caagcgtaca cggactcgta cgcgcgctat gatgacagct
     6181 atttcagata agattcggag tgtagatcag gtttttgtag tcggtcacaa aaatttagac
     6241 atggatgctt tgggctctgc tgtaggtatg cagttgttcg ccagcaatgt gattgaaaat
     6301 agctatgctc tttatgatga agaacaaatg tctccagata ttgaacgagc tgtttcattc
     6361 atagaaaaag aaggagttac gaagttgttg tctgttaagg atgcattggg gatggtgacc
     6421 aatcgttctt tgttgattct tgtagaccat tcaaagacag ccttaacatt atcaaaagaa
     6481 ttttatgatt tatttaccca aaccattgtt attgaccacc atagaaggga tcaggatttt
     6541 ccagataata cggtcattac ttatatcgaa agtggtgcaa gtagtgccag tgagttggta
     6601 acggaattga ttcagttcca gaattctaag aaaaatcgtt tgagtcgtat gcaagcaagt
     6661 gtcttgatgg ctggtatgat gttggatact aaaaatttca cctcgcgagt aactagtcgg
     6721 acatttgatg ttgctagcta tctcagaacg cgcggaagtg atagtattgc tatccaggaa
     6781 atcgctgcga cagattttga agaatatcgt gaggtcaatg aacttatttt acaggggcgt
     6841 aaattaggtt cagatgtact aatagcagag gctaaggaca cgaaatgcta tgatacagtt
     6901 gttattagta aggcagcaga tgccatgtta gccatgtcag gtattgaagc gagttttgtt
     6961 cttgcgaaga atacacaagg atttatctct atctcagctc gaagtcgtag taaactgaat
     7021 gtacaacgga ttatggaaga gttaggcggt ggaggccact ttaatttggc agcagctcaa
     7081 attaaagatg taaccttgtc agaagcaggt gaaaaactga cagaaattgt attaaatgaa
     7141 ataaaggaaa aggagaaaga agaatgaaag taatcttttt agcagatgtt aaaggaaaag
     7201 gtaaaaaagg cgaaattaag gaagtaccaa cagggtatgc gcaaaacttt cttatcaaaa
     7261 agaatctagc caaagaagcg actgctcaag ctgtaggtga acttcgtggt aaacaaaaat
     7321 cggaagaaaa agctcacgct gagatgattg cagaaggaaa agcaattaaa gcacaacttg
     7381 aagcagaaga aactgttgta gaatttgttg aaaaagttgg tccagatggt cgtacctttg
     7441 gctctattac caataagaag attgcagaag aattgcaaaa acaatttgga attaagattg
     7501 ataaacgtca tattcaagta caagctccga ttcgagcggt tggtttgatt gatgtgccag
     7561 tgaaaatcta tcaagatatc acaagtgtaa tcaatcttcg tgtgaaagaa ggataagttt
     7621 acaccttctt gacaagattg taaaaggaag ggaagtctga tggcagaagt agaagagtta
     7681 cgagtacaac ctcaagatat cttagctgag caatccgttt taggggctat ctttattgat
     7741 gagagtaaac ttgtttttgt gcgagaatac attgagtctc gggacttttt taagtatgcc
     7801 catcgtttga ttttccaagc catggtcgat ttatccgatc gtggtgatgc catagatgca
     7861 acaacggttc gtactatcct tgataatcaa ggtgatttac agaatattgg tggcttgtct
     7921 tacttggttg agattgttaa ttctgtgcca acttctgcta atgcggagta ttatgctaag
     7981 attgttgcag aaaaagcaat gctacgtcgt ttaattgcca agttgacaga gtctgtcaac
     8041 caagcttacg aagcgtcaca accagctgat gaaattattg ctcaggcaga aaaagggctg
     8101 attgatgtca gtgaaaatgc aaatcgaagc gggtttaaga acattcgaga tgtgttgaat
     8161 ctcaactttg gaaatctgga agctcgctcg caacaaacga ccgatattac aggtattgcg
     8221 acaggttatc gtgatttgga tcatatgaca acaggacttc atgaggagga gttgattatc
     8281 ttagcagctc gtccagcagt tggtaagaca gcatttgcct tgaatatcgc tcagaacatt
     8341 gggactaagt tggacaaaac ggttgctatt ttttcactcg aaatgggtgc ggaaagcttg
     8401 gtagatcgta tgttagctgc agaaggctta gtggagtcac attctatccg tacagggcaa
     8461 ttgacagatg aggagtggca aaaatatact attgctcagg gtaatctagc taacgccagt
     8521 atctatatcg atgatacgcc aggtattcgg attacagaga ttcgttctcg ttctcgtaaa
     8581 ttggctcaag aaactggaaa tcttggtttg attttgatag actatttgca acttatcacg
     8641 ggaactggtc gagaaaatcg tcaacaagaa gtttctgaaa tttctcgtca gttgaaaata
     8701 ctagccaagg aattgaaggt tccagtaatc gctctgagtc agctttctcg tggtgtagaa
     8761 caacgtcagg acaagagacc ggtcttgtct gatattcgtg aatctgggtc tattgagcag
     8821 gacgctgata tcgtagcttt tctctatcgc gatgactact atgaacgtgg tggtgaagaa
     8881 gaggagggta tcccaaataa taaggtggaa gttattatcg agaaaaaccg tagtggagct
     8941 cgtggaacag tggaattgat tttccaaaaa gaatacaata aattttcaag tatctcaaag
     9001 agggaggcat aagatgtcag atgcatttac agatgtagcc aagatgaaaa aaatcaaaga
     9061 agaaatcaag gcacatgagg gacaagtcgt agaaatgact ttggagaatg gtcgtaagcg
     9121 ccaaaaaaat agattgggta agctaattga agtttatcca tctctattta ttgtggagtt
     9181 tggggatgtg gaaggagata aacaagttaa tgtttacgtt gaatccttta cttactcaga
     9241 tattcttaca gaaaagaatt tgattcatta tcttgactaa agtgagaaat tttctcactt
     9301 tttctttttt ctccgaataa tttaggtgaa ggcaatcatc gctttatatt atttttcaag
     9361 gaggaagaat gaaaatttta ccgtttatag caagaggaac aagttattac ttgaagatgt
     9421 cagttaaaaa gcttgttcct tttttagtag taggattgat gctagcagct ggtgatagtg
     9481 tctatgccta ttccagagga aatggatcga ttgcgcgtgg ggatgattat cctgcttatt
     9541 ataaaaatgg gagccaggag attgatcagt ggcgcatgta ttctcgtcag tgtacttctt
     9601 ttgtagcctt tcgtttgagt aatgtcaatg gttttgaaat tccggcagct tatggaaatg
     9661 cgaatgaatg gggacatcgt gctcgtcggg aaggttatcg tgtagataat acaccgacga
     9721 ttggttccat tacttggtct actgcaggaa cttatggtca tgttgcctgg gtgtcaaatg
     9781 taatgggaga tcagattgag attgaggaat ataactatgg ttatacagaa tcctataata
     9841 aacgagttat aaaagcaaac acgatgacag gatttattca ttttaaagat ttggatggtg
     9901 gcagtgttgg gaatagtcaa tcctcaactt caacaggcgg aactcattat tttaagacca
     9961 agtctgctat taaaactgaa cccctagtta gtgcaactgt gattgattac tattatcctg
    10021 gagagaaggt tcattatgat caaattctcg aaaaagacgg ctacaagtgg ttgagttata
    10081 ctgcctataa tggaagctat cgttatgttc aattggaggc tgtgaataaa aatcctctag
    10141 gtaattctgt tctttcttca acaggtggaa ctcattattt taagaccaag tctgctatca
    10201 aaactgaacc cctagttagc ggaactgtga ttgattacta ttatcctggg gagaaggttc
    10261 attatgatca gatacttgaa aaagacggct acaagtggtt gagttatact gcctataatg
    10321 gaagtcgtcg ctatatacag ctagagggag tgacttcttc acaaaattat cagaatcaat
    10381 caggaaatat ctctagctat ggatccaata atagttcaac tgtcggttgg aagaaaataa
    10441 atggtagttg gtatcatttc aaatcaaatg gttctaaatc aacaggatgg ctgaaagacg
    10501 gttctagctg gtattatttg aaattatctg gtgaaatgca gacaggatgg ttaaaggaga
    10561 atggctcgtg gtattatctg ggtagttcag gggcaatgaa aacaggctgg taccaggtct
    10621 ctggtaagtg gtattattct tactcttcag gcgccttagc tgttaatacg acggtggatg
    10681 gctacagagt aaacagtgat ggagaacgag tatagaaaat tggagtagga gaaatttcct
    10741 gctcttttct gtaagcagtt tccttgacat ttttcttatt ttgcgctatc atatatacat
    10801 ataatatatg ggagtctgtg tacagtctga gaggaagtgt taaacttcga ccgcacctga
    10861 tctgggtaat gccagcggag ggaacgatac ttagtctaat tttgcacctt ttccatgtat
    10921 ggtaaaggtt tttctttttt ttaaaaggaa aacgagaaga ggaggttctt atgaaagcaa
    10981 gcattgcctt gcaagtttta cccctagcac aggggattga tcggatagct gttattgatc
    11041 aggtcattgc ttatctgcaa actcaagaag tgacgatggt agtgacacca tttgaaacgg
    11101 tcttggaagg ggagtttgat gagcttatgc gcattctaaa agaagcgctg gaagtggcag
    11161 ggcaggaggc agacaatgtc tttgccaatg tcaaaataaa tgtaggagag attttaagta
    11221 ttgatgagaa acttgaaaag tatactgaga cgacacatta gtctattggg ctttctcgga
    11281 gtattgtcaa tctggcagtt agcaggtttt cttaaacttc tccccaagtt tatcctgccg
    11341 acacctcttg aaattctcca gccctttgtt cgtgacagag aatttctctg gcaccatagc
    11401 tgggcgacct tgagagtggc tttactgggg ctgattttgg gagttttgat tgcctgtctt
    11461 atggctgtgc tcatggatag tttgacttgg ctcaatgacc tgatttaccc tatgatggtg
    11521 gtcattcaga ccattccgac cattgccata gctcctatcc tggtcttgtg gctgggttat
    11581 gggattttgc ccaagattgt cttgattatc ttaacaacaa cctttcccat catcgttagt
    11641 attttggacg gttttaggca ttgtgacaag gatatgctga ctttgtttag tctgatgcga
    11701 gcaaaccctt ggcaaatcct gtggcatttt aaaatcccgg ttagcctgcc ttacttttat
    11761 gcaggtctga gggtcagtgt ctcctacgcc tttatcacaa ctgtggtatc tgagtggttg
    11821 ggaggttttg aaggtcttgg tgtttatatg attcagtcta aaaaactgtt tcagtatgat
    11881 accatgtttg ccattattat tctggtgtcg attatcagtc ttttgggtat gaagctggtc
    11941 gatatcagtg aaaaatatgt gattaaatgg aaacgtactt aaaatagagc gtttttgaaa
    12001 aagaaaagag gaaatcaaaa tgaagaaaac atggaaagtg tttttaacgc ttgtaacagc
    12061 tcttgtagct gttgtgcttg tggcctgtgg tcaaggaact gcttctaaag acaacaaaga
    12121 ggcagaactt aagaaggttg actttatcct agactggaca ccaaatacca accacacagg
    12181 gctttatgtt gccaaggaaa aaggttattt caaagaagct ggagtggatg ttgatttgaa
    12241 attgccacca gaagaaagtt cttctgactt ggttatcaac ggaaaggcac catttgcagt
    12301 gtatttccaa gactacatgg ctaagaaatt ggaaaaagga gcaggaatca ctgccgttgc
    12361 agctattgtt gaacacaata catcaggaat catctctcgt aaatctgata atgtaagcag
    12421 tccaaaagac ttggttggta agaaatatgg gacatggaat gacccaactg aacttgctat
    12481 gttgaaaacc ttggtagaat ctcaaggtgg agactttgag aaggttgaaa aagtaccaaa
    12541 taacgactca aactcaatca caccgattgc caatggcgtc tttgatactg cttggattta
    12601 ctacggttgg gatggtatcc ttgctaaatc tcaaggtgta gatgctaact tcatgtactt
    12661 gaaagactat gtcaaggagt ttgactacta ttcaccagtt atcatcgcaa acaacgacta
    12721 tctgaaagat aacaaagaag aagctcgcaa agtcatccaa gccatcaaaa aaggctacca
    12781 atatgccatg gaacatccag aagaagctgc agatattctc atcaagaatg cacctgaact
    12841 caaggaaaaa cgtgactttg tcatcgaatc tcaaaaatac ttgtcaaaag aatacgcaag
    12901 cgacaaggaa aaatggggtc aatttgacgc agctcgctgg aatgctttct ataaatggga
    12961 taaagaaaat ggtatcctta aagaagactt gacagacaaa ggcttcacca acgaatttgt
    13021 gaaataatga cagaaattag actagagcat gtcagttatg cctatggtca ggagaggatt
    13081 ttagaggata tcaacctaca ggtgacttca ggcgaagtgg tttccattct aggcccaagt
    13141 ggtgttggaa agaccaccct ctttaatcta atcgctggga ttttagaagt tcagtcaggg
    13201 agaattgtcc ttgatggtga agaaaatccc aaggggcgcg tgagttatat gttgcaaaag
    13261 gatctgctct tggagcacaa gacggtgctt ggaaatatca ttctgcccct cttgattcaa
    13321 aaggtggata aggcagaagc tatttcccga gcggataaaa ttcttgcgac cttccagctg
    13381 acagctgtaa gagacaagta tcctcatgaa cttagcggtg ggatgcgcca gcgtgtagcc
    13441 ttactccgga cctacctttt tgggcacaag ctctttctct tagatgaggc ctttagcgcc
    13501 ttggatgaga tgacaaagat ggaactccac gcttggtatc ttgagattca caaacagttg
    13561 cagctaacaa ccctgatcat cacgcatagt attgaggagg ccctcaatct cagcgaccgt
    13621 atctatatct tgaaaaatcg ccctgggcag attgtttcag aaattaaact agattggtct
    13681 gaagatgagg acaaggaagt ccaaaagatt gcctacaaac gtcaaatctt ggcagaatta
    13741 ggcttagata agtagaaaaa tagggagttg gtgaagatta tcctttacca gcgccctttt
    13801 tcttttaaaa atgagaaaat ttcggtataa tagtcaaaca aggtcaaggt ttaaagagag
    13861 aggtgggttt gttatgagat ttaaaaatac atcggatcat attgaggcct acatcaaggc
    13921 gattttagat caatctggta tcgtggagtt gcaacggagt cagttggcag atacctttca
    13981 ggttgttcct agtcagatta actacgtgat caagacacgc tttacggaaa gtagaggcta
    14041 cttggttgaa agtaagcgtg gtggcggagg ctacattcgt ataggacgga ttgagttttc
    14101 tagtcatcat gaaatgctcc gggagctgct ttactcgatt ggtgagcgag tcagtcaaga
    14161 aatttatgag gatattctcc agcttttggt tgagcaggaa ttgatgacca agcaggagat
    14221 gaatttgcta gaatcagtag ctttggatcg cgttttagga gaagaagctc cagttgttcg
    14281 agcaaacatg ctacgtcagg tcatacaaga ggtagataga aaagggaagt aagatgaact
    14341 attcaaaagc attgaatgaa tgtatcgaaa gtgcctacat ggttgctgga cattttggag
    14401 ctcgttatct agagtcgtgg cacttgttga ttgccatgtc taatcacagt tatagtgtag
    14461 caggggcaac tttaaatgat tatccgtatg agatggaccg tttagaagag gtggctttgg
    14521 aactgactga aacggactat agccaggatg aaacctttat ggaattgccg ttctcccgtc
    14581 gtttgcaggt tctttttgat gaagcagagt atgtagcgtc agtggtccat gctaaggtac
    14641 tagggacaga gcacgtcctc tatgcgattt tgcatgatgg caatgccttg gcgactcgta
    14701 tcttggagag ggctggtttt tcttatgaag acaagaaaga tcaggtcaag attgctgctc
    14761 ttcgtcgaaa tttagaagaa cgggcaggct ggactcgtga agatctcaag gctttacgcc
    14821 aacgccatcg tactgtggct gacaaacaaa attctatggc caatatgatg ggcatgccgc
    14881 agactcctag tggtggtctc gaggactata cgcatgattt gacagagcaa gcgcgttctg
    14941 gcaagttaga accagtcatc ggtcgggaca aggaaatctc acgtatgatt caaatcttga
    15001 gccgtaagac taagaacaac cctgtcttgg ttggggatgc tggtgtcggg aaaacagctc
    15061 tggtgcttgg tcttgctcag cgtattgcca gtggtgatgt gcctgcggaa atggctaaga
    15121 tgcgcgtgtt agaacttgat ttgatgaatg tcgttgcagg gacacgcttc cgtggtgact
    15181 ttgaagaacg catgaataat atcatcaagg atattgaaga agatggccaa gtcatcctct
    15241 ttatcgatga actccacacc atcatgggtt ctggtagcgg gattgattcg actctggatg
    15301 cggccaatat cttgaaacca gccttggcgc gtggagcttt gagaacggtt ggtgccacca
    15361 ctcaggaaga atatcaaaaa catatcgaaa aagatgcggc tctttctcgt cgtttcgcta
    15421 aagtgacgat tgaagaacca agtgtggcag atagtatgac tattttacaa ggtttgaagg
    15481 cgacttatga gaaacatcac cgtgtacaaa tcacagatga agcggttgaa acagcggtta
    15541 agatggctca tcgttattta accagtcgtc acttgccaga ctctgctatc gacctcttgg
    15601 acgaagcagc agcaacagtg caaaataagg taaagtatgt aaaagcagac gattcagatt
    15661 tgagtccagc tgataaggcc ctgatggatg gcaagtggaa acaggcagcc cagctaatcg
    15721 caaaagaaga ggaagtacct gtctacaaag acttggtgac agagtctgat attttgacca
    15781 ccttgagtcg cttgtcagga atcccagttc aaaaactgac tcaaacggat gctaagaagt
    15841 atctaaatct tgaagcagaa ctccataaac gtgtcatcgg tcaagatcaa gctgtttcaa
    15901 gcattagtcg tgcgattcgc cgtaatcagt caggaattcg cagtcacaag cgtccgatcg
    15961 gttcctttat gttcctagga cccacaggtg tcggtaagac cgagttggcc aaggctttgg
    16021 cagaagttct ctttgatgac gaatcagccc ttatccgctt tgatatgagt gagtatatgg
    16081 agaaattcgc agccagccgt ctaaatggag ctcctccagg ctatgtgggt tacgaagaag
    16141 gtggagagtt gacagagaag gttcgcaata aaccctattc cgttctcctc tttgatgagg
    16201 tagagaaggc ccacccagat atttttaatg ttctcttgca ggttctggat gacggtgttt
    16261 tgacagatag caagggacgc aaggtcgatt tttcaaatac cattatcatt atgacatcga
    16321 acctaggtgc gactgccctt cgtgatgata agactgttgg ttttggggct aaggatattc
    16381 gttttgacca ggaaaatatg gaaaaacgca tgtttgaaga actgaaaaaa gcttatagac
    16441 cggaattcat caaccgtatt gatgagaagg tggtcttcca tagcctatct agtgaccata
    16501 tgcaggaagt ggtgaagatt atggtcaagc ctttagtggc aagtttggct gaaaaaggca
    16561 ttgacttgaa attacaagct tcagctctga aattgttagc aaatcaagga tatgacccag
    16621 agatgggagc tcgcccactt cgcagaaccc tgcaaacaga agtggaggac aagttggcag
    16681 aacttcttct taagggagat ttagtggcag gcagcacact taagattggt gtcaaagcag
    16741 gccagttaaa atttgatatt gcataaaaga ataaaagtat cagcatctga ccataagtca
    16801 cagtggagtg aaactcaatg aaaatcaaag agcaaactag gcagctagcc gcaggttgct
    16861 caaaacactg gtttgaggtt gcagatagag ctgacgtggt ttgaagagat tttcgaagag
    16921 tatgaaacta aaacctatag cttctaaacg atccgtggtt ttcaccattc aacacaaaat
    16981 tcatatgttt attaccctcc gtcgtatttg tcttagagcg tgtgtagtag aaaaagagca
    17041 gtcttatctg aaatttttat tctttcaaaa gagacctgtt tcttttttgc atgtcaaatc
    17101 cgttctagct ggtatttgaa aaatcaaact aatattcaat gaaaatcaaa gaacaaacta
    17161 ggcagctagc cacaggttgc tcaaaacact gttttgaggt tgtagataga gctgacgtag
    17221 tttgaagaga ttttcgaaga gtataagctg caagatgaat gattttcttg tattgacgtt
    17281 gttgttgaca aaaagtagcg gataaatgaa atccattcca ttatcataga tgataggctg
    17341 gtaggaaatt ttcaaatagc atacaggaaa tagatgtatg gagttctggt agtagaaagg
    17401 gagagagatg aacattttag ttgcagatga cgaggaaatg attagagaag gaattgcagc
    17461 atttctgaca gaagagggtt atcatgtcat tatggctaag gatggacaag aggtcttgga
    17521 aaaatttcaa gatctcccta tccatctcat ggtattggat ttaatgatgc ctaggaagag
    17581 tggttttgaa gtgttaaaag aaatcaatca aaagcacgat attcctgtca tcgtcttgag
    17641 tgctctggga gatgaaacta ctcagtcaca ggtatttgat ctctatgctg atgatcatgt
    17701 gacaaaacct ttttctttgg tactgcttgt caagcgtatt aaggcgctta tcagacgtta
    17761 ctacgtcata gaggatattt ggcgatatca ggatgtaaca gtggatttta cctcttacaa
    17821 agcacattat aaaaatgaag aaattgatct caaaccaaag gaattactgg tactaaagtg
    17881 tttgattcag cataaaaatc aagttttaag tagagagcag atattggaag aaatttcaaa
    17941 agatgtagct gatttacctt gtgatagggt cgttgatgtc tatattcgta ctcttcgcaa
    18001 aaaattagct ttagattgta tcgtgactgt gaaaaatgtt gggtataaga ttagcttatg
    18061 ataaaaaatc ctaaattatt aaccaagtct tttttaagaa gttttgcaat tctaggtggt
    18121 gttggtctag tcattcatat agctatttat ttgacctttc ctttttatta tattcaactg
    18181 gagggggaaa agtttaatga gagcgcaaga gtgtttacgg agtatttaaa gactaagaca
    18241 tctgatgaaa ttccaagctt actccagtct tattcaaagt ccttgaccat atctgctcac
    18301 cttaaaagag atattgtaga taagcgactc cctcttgtgc atgacttgga tattaaagat
    18361 ggaaagctat caaattatat cgtgatgtta gatatgtctg ttagtacagc agatggtaaa
    18421 caggtaacag tgcaatttgt tcacggggtg gatgtctaca aagaagcaaa gaatattttg
    18481 tttttgtatc ttccatatac atttttggtt acaattgctt tttcctttgt tttttcttat
    18541 ttttatacta aacgcttgct caatcctctt ttttacattt cagaagtgac tagtaaaatg
    18601 caagatttgg atgacaatat tcgttttgat gaaagtagga aagatgaagt tggtgaagtt
    18661 ggagaagttg gaaaacagat taatggtatg tatgagcact tgttgaaggt tattcatgag
    18721 ttggaaagtc gtaatgagca aattgtaaaa ttgcaaaatc aaaaggtttc ctttgtccgt
    18781 ggagcatcac atgagttgaa aaccccttta gccagtctta gaattatcct agagaatatg
    18841 cagcataata ttggagatta caaagatcat ccaaaatata ttgcaaagag tataaataag
    18901 attgaccaga tgagccactt attggaagaa gtactggagt cttctaaatt ccaagagtgg
    18961 acagagtgtc gtgagacctt gactgttaag ccagttttag tagatatttt atcacgttat
    19021 caagaattag ctcattcaat aggtgttaca attgaaaatc aattgacaga tgctaccagg
    19081 gtcgtcatga gtcttagggc attggataag gttttgacaa acctgattag taatgcaatt
    19141 aaatattcag ataaaaatgg gcgcgtaatc atatccgagc aagatggcta tctctctatc
    19201 aaaaatacat gtgcgcctct aagtgaccaa gaactagaac atttatttga tatattctat
    19261 cattctcaaa tcgtgacaga taaggatgaa agttccggtt tgggtcttta cattgtgaat
    19321 aatattttag aaagctatca aatggactat agttttctcc cttatgaaca cggtatggaa
    19381 tttaagatta gcttgtagac agattagttt tttattaaag ttcatatagg gttaacataa
    19441 gtgtgttatt ctttgtgtag ataaaagaaa ggatactaat atggtattag cgattatttt
    19501 agtaacattc tttattcgat tgattttttt aaagcgttcg atagagaatg agaaacgaat
    19561 ccttagcaat ggcgggaaag aatttggagt tgagaataca aaacgattaa ctatggctca
    19621 tattgttttt tatctctctt gcttggttga ggcaatggtg cacaagacaa tttttgatgg
    19681 catgggcatg gttggtttag tcttgcttat tttttctatg ctgatgttaa tgttggtgat
    19741 tcacttgttg ggagatattt ggacagtgaa gcttatgctt gtcaataatc acaaatatgt
    19801 agatcatatc ttgtttagga cagtaaaaca tcctaattac tttttaaata ttcttcctga
    19861 gttgattggc ttgaccttgt tgagtcatgc ttatgtgact tttgttttag tttttccagt
    19921 ttatgcagtt attttgtatc gacgaatagc tgaagaggaa aagctattac atgaagttat
    19981 aatcccaaat ggaagcataa agagataaat acaaaattcg atttatatac agttcatatt
    20041 gaagtgatat agtaaggtta aagaaaaaat atagaaggaa ataaacatgt ttgcatcaaa
    20101 aagcgaaaga aaagtacatt attcaattcg taaatttagt attggagtag ctagtgtagt
    20161 agttgctagc ttgttcttag gaggagtagt tcatgcagaa ggggttagaa gtggggatac
    20221 ccccaaggtt acatctagtg gggatgaagt cgagtcgcat ctaaaaaaaa tattgagtga
    20281 gatccaaaca caattagata gaaaacgaca tgccaaaact gtagcgctaa ttaacaagtt
    20341 gcaagacatt aagagaacgt attcgtataa attaaatgtt ttagaagaga agccgaaagc
    20401 tgagttgacg tcaaaaacaa aagaagagtt aaccgcagct tttgagcaat ttaaaaaaga
    20461 tacattacca acagaaccag gaaaaaaggt agcagaagct gagaagaagg ttgcagaagc
    20521 tgagaaaaaa gccgaggatc aaaaagaaga agatcgtcgt aactacccaa ccaatactta
    20581 caaaacgctt gaacttgaaa ttgctgagtt cgatgtgaaa gttaaagaag cggagcttga
    20641 actattaaaa gagaaagcta agaaaccttt aaacgagggc acaattaagc aagcaaaaga
    20701 gaaagttgag agtaaaaaag ctgaggctac aaggttagaa aacatcaaga cagatcgtaa
    20761 aaaagcagaa gaagaagcta aacgaaaagc agcagaagaa gataaagtta aagaaaaacc
    20821 agctgaacaa ccacaaccag cgccggctcc tcaaccagaa aaaccagctc caaaaccaga
    20881 aaaaccagct ccagctccaa aaccagagaa tccagctcca aaaccagaaa aaccagctcc
    20941 agctccaaaa ccagagaatc cagctgaaca accaaaagca gaaaaaccag ctgatcaaca
    21001 agctgaagaa gactatgctc gtagatcaga agaagaatat aatcgcttga ctcaacagca
    21061 accgccaaaa actgaaaaac cagcacaacc atctactcca aaaacaggct ggaaacaaga
    21121 aaacggtatg tggtacttct acaatactga tggttcaatg gcgacaggat ggctccaaaa
    21181 caatggctca tggtactacc tcaacagcaa tggcgctatg gcgacaggat ggctccaaaa
    21241 caatggttca tggtactatc taaacgctaa tggttcaatg gcaacaggat ggctccaaaa
    21301 caatgg
//
LOCUS       DAVBCA010000036        21177 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.036, whole genome shotgun sequence.
ACCESSION   DAVBCA010000036 DAVBCA010000000
VERSION     DAVBCA010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21177)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21177)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21177
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.036"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            3..350
                     /locus_tag="VQU19_001298"
     CDS             3..350
                     /locus_tag="VQU19_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480545.1"
                     /translation="MLRLPYKKQKISHFTVSEDKDICRYIRQQLYYQNLFWMKEQAEA
                     YQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPP
                     AFYQQYFLKNMVE"
     gene            369..2171
                     /gene="pepF"
                     /locus_tag="VQU19_001299"
     CDS             369..2171
                     /gene="pepF"
                     /locus_tag="VQU19_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HET2480546.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEVLKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQMEKLYVYAHMKNDQDTREAKYQEYYAKAMTFYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGIYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            2173..2886
                     /locus_tag="VQU19_001300"
     CDS             2173..2886
                     /locus_tag="VQU19_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HET2480547.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELENFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            2953..3894
                     /gene="prsA"
                     /locus_tag="VQU19_001301"
     CDS             2953..3894
                     /gene="prsA"
                     /locus_tag="VQU19_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HET2480548.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(4011..4352)
                     /locus_tag="VQU19_001302"
                     /pseudo
     CDS             complement(4011..4352)
                     /locus_tag="VQU19_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            4765..4860
                     /locus_tag="VQU19_001303"
                     /pseudo
     CDS             4765..4860
                     /locus_tag="VQU19_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(5113..5733)
                     /locus_tag="VQU19_001304"
     CDS             complement(5113..5733)
                     /locus_tag="VQU19_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET2480549.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLYTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(5733..6215)
                     /locus_tag="VQU19_001305"
     CDS             complement(5733..6215)
                     /locus_tag="VQU19_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HET2480550.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDRMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(6215..7057)
                     /locus_tag="VQU19_001306"
     CDS             complement(6215..7057)
                     /locus_tag="VQU19_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HET2480551.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDLKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(7152..7952)
                     /locus_tag="VQU19_001307"
     CDS             complement(7152..7952)
                     /locus_tag="VQU19_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HET2480552.1"
                     /translation="MRKQIHPLILFSFFGIMMFILIINRPLNDSQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            8096..9475
                     /gene="glmU"
                     /locus_tag="VQU19_001308"
     CDS             8096..9475
                     /gene="glmU"
                     /locus_tag="VQU19_001308"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HET2480553.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            9485..10030
                     /locus_tag="VQU19_001309"
     CDS             9485..10030
                     /locus_tag="VQU19_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET2480554.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTARRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            10042..10356
                     /locus_tag="VQU19_001310"
     CDS             10042..10356
                     /locus_tag="VQU19_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HET2480555.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            10373..11065
                     /locus_tag="VQU19_001311"
     CDS             10373..11065
                     /locus_tag="VQU19_001311"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HET2480556.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNTQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLTFLKALD"
     gene            11142..11633
                     /gene="rocS"
                     /locus_tag="VQU19_001312"
     CDS             11142..11633
                     /gene="rocS"
                     /locus_tag="VQU19_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HET2480557.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            11731..12321
                     /locus_tag="VQU19_001313"
     CDS             11731..12321
                     /locus_tag="VQU19_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HET2480558.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGVLDLSQLFD"
     gene            12330..14093
                     /locus_tag="VQU19_001314"
     CDS             12330..14093
                     /locus_tag="VQU19_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HET2480559.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTCAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDKYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
     gene            14307..14785
                     /locus_tag="VQU19_001315"
                     /pseudo
     CDS             14307..14785
                     /locus_tag="VQU19_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            14952..15152
                     /locus_tag="VQU19_001316"
     CDS             14952..15152
                     /locus_tag="VQU19_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480560.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDPK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            15177..15593
                     /locus_tag="VQU19_001317"
     CDS             15177..15593
                     /locus_tag="VQU19_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480561.1"
                     /translation="MKAALDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETN
                     SVPAGVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKA
                     QNLLQETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            15824..16531
                     /gene="ccdA2"
                     /locus_tag="VQU19_001318"
     CDS             15824..16531
                     /gene="ccdA2"
                     /locus_tag="VQU19_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HET2480562.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYVMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            16542..17099
                     /gene="sdbB"
                     /locus_tag="VQU19_001319"
     CDS             16542..17099
                     /gene="sdbB"
                     /locus_tag="VQU19_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HET2480563.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIA
                     VGKDAPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            17220..18611
                     /locus_tag="VQU19_001320"
     CDS             17220..18611
                     /locus_tag="VQU19_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HET2480564.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPSWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIAFPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            18754..19671
                     /gene="adcAII"
                     /locus_tag="VQU19_001321"
     CDS             18754..19671
                     /gene="adcAII"
                     /locus_tag="VQU19_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HET2480565.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLESDPQNDKTYLENLEENMSILAEELK"
     gene            19679..>21177
                     /locus_tag="VQU19_001322"
     CDS             19679..>21177
                     /locus_tag="VQU19_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET2480566.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRHQAGQVKKESNRVSYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVDGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGNHFHYIPKSDL
                     SASELAAAQAYWNGKQGSRPSSSSSHNANPAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGLVFDPAQITYRTVNGVAVPHGDHYHFIPYSQLSPLEEKLA
                     RMIAVKGQNGAVLPGMHYLKPAPKPQVQPSTEKKQTDFAVEQVVRKVGEGYVVEIAGV
                     SHYVFAKDLAKDKIDAIENLLSKKTQETHALVAKKENVAPRDQEFYDKAYNLLTQAHK
                     VLSENKGRTSDFQALDKLAERLNNESSNKVKLVDDLLAFLAPITHPERLG"
BASE COUNT         6646 a         3794 c         4414 g         6323 t
ORIGIN      
        1 aaatattgcg tcttccctat aagaaacaaa aaatatctca ttttacagtt tctgaggaca
       61 aggacatctg tcgctatatc cggcaacaac tttattatca aaatctcttt tggatgaaag
      121 aacaagcaga agcctatcaa aagggagaaa atatcctgac ttatggactg aaagaatggt
      181 atccacaaat tcgaccaata gtgggcaaat ttttccagat tgaacaagac ttgactagct
      241 attatcagca cttttatacc tattaccaaa aaaatcctca aaatgattgg caaaagcttt
      301 atccaccagc cttttatcag caatatttct tgaaaaatat ggtagaatag aaaggatgga
      361 ggaatctaat ggtattacaa agaaatgaaa taaatgaaaa agatacatgg gatctatcaa
      421 cgatctaccc aactgaccag gcttgggaag aagtcttaaa agatttaaca gaacaattgg
      481 agacagtagc ccagtatgaa ggccatctct tggatagtgc ggataaccta ctagaaatca
      541 ctgaattttc tcttgaaatg gaacgccaga tggagaagct ttacgtttat gctcatatga
      601 agaatgacca ggatacacgt gaagctaagt atcaagagta ctatgccaag gccatgacat
      661 tctacagcca gttagaccaa gccttttcat tctatgagcc tgaatttatg gagattagcg
      721 aaaagcagta tgctgacttt ttagaagctc aaccaaagct gcaggtttat caacactatt
      781 ttgacaagct cttgcaaggc aaggatcacg ttctctcaca acgtgaagaa gaattattgg
      841 ctggagctgg agaaatcttt ggttcagcaa gtgaaacctt cgctatcttg gacaatgcgg
      901 atattgtgtt cccttatgtc ctagacgatg atggtaaaga agttcagcta tctcatggga
      961 tttacacacg tttgatggag tctaaaaaac gtgaggttcg ccgtggtgcc tatcaagctc
     1021 tttatgcgac ttacgaacaa ttccaacaca cctatgccaa aaccttgcaa accaatgtta
     1081 aggtgcaaaa ttaccgtgct aaagttcgta actacaagag tgctcgtcat gcagccctcg
     1141 cagcgaattt tgttccagaa agtgtttatg acaatttggt agcagcagtt cgcaagcatt
     1201 tgccactctt acatcgctat cttgagcttc gttcaaaaat cttggggatt tcagatctca
     1261 agatgtacga tgtctacaca ccgctttcat ctgttgaata cagttttacc taccaagaag
     1321 ccttgaaaaa agcagaagat gctttggcag tcttgggtga ggattacttg agccgtgtta
     1381 aacgtgcctt cagcgagcgt tggattgatg tttacgaaaa tcaaggcaag cgttcaggtg
     1441 cctactctgg tggttcttac gataccaatg cctttatgct tctcaactgg caggacaatc
     1501 tggacaatct ctttactctt gttcatgaaa caggtcacag tatgcattca agctatactc
     1561 gtgaaactca gccttatgtt tacggagatt actctatctt tttggctgag attgcctcaa
     1621 ctaccaatga aaatatcttg acggagaaat tattggaaga agtggaagac gacgcaacac
     1681 gctttgctat tctcaataac ttcctagatg gtttccgtgg aacagttttc cgccaaactc
     1741 aatttgctga gtttgaacac gccattcacc aagcagatca aaatggggag gtcttgacaa
     1801 gcgatttcct aaataaactc tacgcagact tgaaccaaga gtattatggt ttgagtaagg
     1861 aagacaatcc tgaaatccaa tacgagtggg ctcgcattcc acacttctac tataactact
     1921 atgtatatca atattcaact ggctttgcgg ccgcctcagc cttggctgaa aaaattgtcc
     1981 atggtagtca agaagaccgt gaccgctata tcgactacct caaggcaggt aagtcggact
     2041 atccacttaa tgtcatgaga aaagctggtg ttgatatgga gaaggaagac tacctcaacg
     2101 atgcctttgc agtctttgaa cgccgtttaa atgagtttga agcccttgtt gaaaaattag
     2161 gattggcata aaatggttga atcgtatagt aagaatgcta accataacat gcgtcgtcct
     2221 gtcgtcaaag aagaaattgt agacttgatg cgtcagcgtc aaaagcaggt cacaggtttc
     2281 ttgaaagaat tggaaaactt tgcccgcaag gaaaatattc ctattattcc ccatgaaacg
     2341 gttgcttatt tccgttttct tatggaaacc atgcagccta aaaatattct ggaaattggg
     2401 acggctatcg gtttttcagc tctcttgatg gctgaacatg cgccaaatgc taagattaca
     2461 actattgatc gtaatccaga aatgattggt tttgccaagg aaaattttgc ccagtttgac
     2521 agtcgcaagc aaatcactct cctagaggga gatgcggtgg atgtcttatc tacactgaca
     2581 gagtcttatg atttcgtctt tatggattct gccaagtcta aatacatcgt ctttctgcca
     2641 gaaatcctca aacatttgga agttggtggt gtggttgtct tggatgatat ttttcaaggt
     2701 ggtgatgttg ccaaggatat tatggaagtc cgtcgtggtc agcgaaccat ttatcgaggc
     2761 cttcaaaaat tatttgatgc aaccttagac aatccagaac tcaccgcaac attagtgcct
     2821 ttaggagatg gtattctcat gcttcgtaaa aatgtagcag atgttcaact gtctgaaagc
     2881 gaatgatttt cagaaaaatt taagaaaaaa tagtaaaata gatagagtaa cacttatctc
     2941 aaaggagtag acatgaagaa aaaattattg gcaggtgcca tcacactatt atcagtagca
     3001 actttagcag cttgttcgaa agggtcagaa ggggcagacc ttatcagcat gaaaggggat
     3061 gtcatcacag aacatcaatt ttatgagcaa gtgaaaaaca acccttcagc ccaacaagtc
     3121 ttgttaaata tgaccatcca aaaagttttt gaaaaacaat atggctcaga gcttgatgat
     3181 aaagaggttg atgatactat tgccgaagaa aaaaaacaat atggcgaaaa ctaccaacgt
     3241 gtcttgtcac aagcaggtat gactcttgaa acacgtaaag ctcaaattcg tacaagtaaa
     3301 ttagttgagt tggcagttaa gaaggtagca gaagctgaat tgacagatga agcctataag
     3361 aaagcctttg atgagtacac tccagatgta acggctcaaa tcatccgtct taataatgaa
     3421 gataaggcca aagaagttct cgaaaaagcc aaggcagaag gtgctgattt tgctcaatta
     3481 gccaaagata attcaactga tgaaaaaaca aaagaaaatg gtggagaaat tacctttgat
     3541 tctgcttcaa cagaagtacc tgagcaagtc aaaaaagccg ctttcgcttt agatgtggat
     3601 ggtgtttctg atgtgattac agcaactggc acacaagcct acagtagcca atattacatt
     3661 gtaaaactca ctaagaaaac agaaaaatca tctaatattg atgactacaa agaaaaatta
     3721 aaaactgtta tcttgactca aaaacaaaat gattcaacat ttgttcaaag cattatcgga
     3781 aaagaattgc aagcagccaa tatcaaggtt aaggaccaag ccttccaaaa tatctttacc
     3841 caatatatcg gtggtggaga ttcaagctca agcagtagta catcaaacga atagtccaaa
     3901 tcaatgagtc agggaaaaaa actcgacttc aggaaaaaat gaagcaaaca ttcccacaat
     3961 aaaacgcata gtacaaggtt tgtactgacc ccaaaagtta gacaattaat ttatctgaag
     4021 gatttagttc tgtattgcac agggctaagt ccttttagtt ttaccttaat tctcttattg
     4081 ttgtaataat caatatagtc tataatggct tgttccaatt gattaagtga tttaaatgtt
     4141 ttctcatagc cataaaacat ttcggatttt aaaatgccaa agaaagattc catcctaccg
     4201 ttgtcttggc tgtttccttt gcgtgacata gatgcttgaa ttcccttact ctctaggaag
     4261 cgatgataag aatcgtgttg gtattgccag ccttggtcac tatggagaat cgtattctcg
     4321 tagtgcttct ctttgaatgc ctgttccaac attaacgatc aatcaattta atcatgtacc
     4381 taatattaga attgtttatc ccaaatttat ttgaaagctt ctctaagcta tatccttgtt
     4441 ttctaagttc atagatctga actttatcat cataagttaa tttcataata aaaacacccc
     4501 aaaagttaga ttttttctgt ctaacttttg gggtgtagtt catgtacacc tgatatgatg
     4561 cgttttataa ttttaaagac tttttgacca gcctcatttt tttaacttga tactcagtga
     4621 aaagcaaaga ttaaactagg aagctagctg taggctgctc aaagaacagc tttgaggttg
     4681 cagataaaac ttgtgaggtc accaacatat ataatgtgaa gctgacgtga cttgaataga
     4741 ttttagaagg gtatgagtct ggaagtttta atggataatg caagattcca tagaatgggt
     4801 aagctagagt tcttatgtga agagtttggg cataaacttt taccttttcc tccctactca
     4861 tcttagtata gaaaagtgaa tctaaaatag tacataactg cttctaaaac attcttataa
     4921 attgatttaa attctcaaat catattattc agttcttatt tcattttgct ctacaatcct
     4981 gttgagaaga cacgtgttca tatcaaaaag gtattggcaa gttgcaatac ctttttacaa
     5041 ggttcttttg tcttattttt gtttcaactg actatatctc ctatggttct agttcagaag
     5101 gctaggctat aattatgatt gataagaagt atcattccaa gtattgagag tgaatgtttc
     5161 aaaatcatgg gtttctataa tggtcaggct ggcatttgct agaccgccat ctttacgaag
     5221 aagtggttct ttatagccta ggagagtacg aagactggca gtaagattgg cgccgtgtcc
     5281 gacaattaga atacgctcag ctggactatc ttttaatgat ttgataaatt ggatggtccg
     5341 ttgagttgta ctatagaggg attcggctcc gaacattcga gtgtcaaatt gagcaagatt
     5401 tgaacgaaaa gcctggattt gttgcgggta aatagcttcc aaggttgcaa ttttcaaacc
     5461 ttctaacttc ccaagttgcc attcacggag attaggaacg atttctaaag aacagggggt
     5521 atagagttga ctttggataa tctcagcaga tttgaccgct cgaggtaaat cacttgaata
     5581 aatctgatca aaaggaattt ccttgagata ctggccaagt cgttttaggg tttcaatgga
     5641 ttcaggaaga agaggagaat caccgctagc accttgaaaa cgaccttctt ggttccagag
     5701 ggtacgaccg tggcggacaa agtagagttt cattacttga tgtcctccaa aatatctaca
     5761 aagtctgcct ttacaaagct agccaagtct tgtggcgcga cgataatgct gtgtccgact
     5821 tcgcctgcag agacaatcat tcgatccaaa tctagagcaa ttttatcgat aaaaatggga
     5881 taattgtgtt tctgacgaat tccgacagga ttattggctc catgaatgta accagttgtt
     5941 ttttctaagt ccttttgtgg aatcatgctc acttttttat tgccagaaat tttagctagt
     6001 ttcttttcag acaagtgctg agtgataggg acaattccga taatcggtcc ggtcttgtct
     6061 cccaaaagcg ccaaggtttt gaaaatctga tctcgttcat aaccttgagg aagctctcct
     6121 tctagggcat tgatttgaat cccctgatga gggatagctg ctttagatag gatttgttcc
     6181 accaatgttt ttttgatttt aacttttttt gccattattt atatttatcc tccaattgac
     6241 tcatccaaat accaagccag attcccagcg caaagaagaa ggcgatgatg acataaccga
     6301 caagtgaaag tcctgtgtat tggatacttt cagcgtttcc tgcatttgga attaagatca
     6361 aaagggtact tgataggacg ataccgatga tgaaatgata gacgcgtgag tggtagttgt
     6421 ttaaggcata atccatcaat tttgaaaaaa cgatgagagt tgcacctgca ccaattccaa
     6481 tcggaaagaa ggttcccaag agatcaaaag ttttaaaacc agtcaacata ggagcataga
     6541 gtcccaaaat caaaagtaag ttcgatgggc tgaggccagg aaccaagacg ccaagggcca
     6601 atagtgcgcc tgctaggacg aagttaagaa agctggcgct taaggttcca acgacaaaat
     6661 ttaaggcata gagtcctaat ccagaaatga taaaggttgt ccataaccaa gctaaatcaa
     6721 tcttgtctcg gtcagattct cgagttgatt ctttgaggag gctaggaact gtaccgataa
     6781 tagctcccgc aaagctccat aatacaaaga cctgataatt ttcaagcagg tattcaatcg
     6841 ggtaggaaaa taagccgatt cccagaagca taccgatggc aactggaata aagtacaaaa
     6901 cattttcttt aaggtcttta aagggatggg ccagaaagcc aatcattcgt tcatagattc
     6961 ctaagattgc tgctagaacc cctccggaaa ttcccggtag gataaatcca agagcaatta
     7021 caatcccttt aataacgcgt gctaaccatg agagcatata tttcctccaa ctatttctat
     7081 ttcaaaaatt ccttactata ttgtatcaca atcagacaca aaaagaaaaa gcaaatgata
     7141 aacaaatgct tttaaggttt taaaaaaagt tttcgaaagg tttcttcttt attttttaag
     7201 ggagagataa cgttgatatc taaatcgtgg tcaaagccgg caatttttcc tttagatgtg
     7261 tattggtgaa tatcataatc taaatcagtt ttaggactgc tctccaaaaa tcctgagtct
     7321 gagccgtagg acggaatcca aacagaggta aacttgcctg tatcaatact gtgttcttcc
     7381 atgaagtaga caccaacgta gatgccgatg tttttagcac ctagtgatgc tagttttgct
     7441 cgaaagtttt cgacaccttc gttcatatta gacatggttt tgtcttccac gtcaagccaa
     7501 tagtaactag ggctgtaagg agaggcagca ttgtagaaaa cttcggcagc cttttccatt
     7561 tcttggacac tttttccagc tacataagcg tagacagcaa ctgggacatt ccgcttttga
     7621 agttcagtga tatgactctt ataggccttg tctattccat tgataaatga agcatcattt
     7681 tcttttgttg tttgagcacc actgtgaaca cgaacaatag cacctgaaat attttgtgag
     7741 agggcatcgt agttgatttc ctcaggacgc tgccagccag agaggtcaat aatcggtttg
     7801 tctaagtgtt tcaaagcctg tgcttcaatc tgtgctatat tggattttgt tttaaacgat
     7861 tggctgtcat taagtgggcg attgatgatt aaaatgaaca tcataatccc aaaaaaacta
     7921 aataaaataa gtggatgaat ttgttttctc atatcttata agtctaccct aaaaatcaaa
     7981 aaaaatcaaa aaaatgggtt aaggaagaga ctttagagca ttttttcatt caagagtgcg
     8041 gaatgatttg aaatatggta taataaaagg gaatttctac agaaaagaga agattatgtc
     8101 aaattttgcc attattttag cagcgggtaa agggactcgc atgaaatctg atttgccaaa
     8161 agttttgcac aaggttgcgg gtatttctat gttggaacat gttttccgta gtgtgggagc
     8221 tatccaacct gaaaagacag taacagttgt aggacacaag gcagaattgg ttgaggaggt
     8281 cttggctgga cagacagaat ttgtgactca atctgaacag ttgggaactg gtcatgcagt
     8341 tatgatgaca gaacctatct tagaaggttt gtcaggacac accttggtca ttgcaggaga
     8401 tactccttta atcactggtg aaagcttgaa aaacttgatt gatttccata tcaatcataa
     8461 aaatgtggcc actatcttga ctgctgaaac ggataatcct tttggctatg gacgaattgt
     8521 tcgtaatgac aatgctgagg ttcttcgtat tgttgagcag aaggatgcta cagattttga
     8581 aaagcaaatc aaggaaatca acactggaac atacgtcttt gacaacgagc gtttgtttga
     8641 ggctttgaaa aatatcaata ccaataacgc tcaaggcgaa tactatatta cagacgtcat
     8701 tggtattttc cgtgaaactg gtgaaaaagt tggcgcttat actttgaaag attttgatga
     8761 aagtcttggg gtaaatgacc gtgtggcgct tgcgacagct gagtcagtta tgcgtcgtcg
     8821 catcaatcat aaacacatgg tcaacggtgt tagctttgtc aatccagaag caacttatat
     8881 cgatattgat gttgagattg ctccggaagt tcaaatcgaa gccaatgtta ccttgaaagg
     8941 gcaaacgaaa attggtgctg agactgtttt gacaaacggt acttatgtag tggacagcac
     9001 tatcggagca ggagcggtca ttaccaattc tatgattgag gaaagtagtg ttgcagacgg
     9061 tgtgacagtc ggtccttatg ctcacattcg tccaaattca agtctgggtg cccaagttca
     9121 tattggtaac tttgttgagg tgaaaggatc ttcaatcggt gagaatacca aggctggtca
     9181 tttgacttat atcggaaact gtgaagtggg aagcaacgtt aatttcggtg ctggaactat
     9241 tacagtcaac tatgacggca aaaacaaata caagacagtc attggagaca atgtctttgt
     9301 tggttcaaat tcaaccatta ttgcaccagt agaacttggt gacaattccc tcgttggtgc
     9361 tggttcaact attactaaag acgtgccagc agatgctatt gctattggtc gcggtcgtca
     9421 gatcaataaa gacgaatatg caacacgtct tcctcatcat cctaagaacc agtaggagcc
     9481 tatcatggag tttgaagaaa aaacgcttag ccgaaaagaa atctatcaag gaccaatatt
     9541 taaactggtc caagatcagg ttgaattacc agaaggcaag ggaactgccc gacgggattt
     9601 gattttccac aatggggctg tctgtgtttt agcagtaacg gatgaacaaa aacttatctt
     9661 ggtcaagcag taccgcaaag ctatcgaggc tgtctcttac gaaattccag ccggaaaatt
     9721 ggaagtagga gaaaacacag cccctgtggc agctgccctt cgtgaattag aggaagaaac
     9781 agcctataca gggaaattag aactcttgta cgatttttat tcagctattg gcttttgtaa
     9841 tgagaagtta aaactatatt tagcaagcga tttgacaaaa gtggaaaatc cgcgtccgca
     9901 ggatgaggat gaaaccttgg aagtccttga agtgagctta gaagaagcga aagaattaat
     9961 ccaatcaggt catatctgtg atgccaagac aattatggct gttcagtatt gggagttgca
    10021 gaaaaaatag aggaggtcag tatgggtaaa tctttattaa cggatgaaat gattgaaaga
    10081 gctaatagag gcgaaaaaat ttcaggtcct cctttgctag atgataatga ggaaactaag
    10141 attttaccaa cctcttcttc ccgttttggt tatgccaatc ctaaggatca tggttttagc
    10201 caggaaacct tgaagattca ggtcgaacca tctattcata aaagccgtcg tattgaaaat
    10261 accaagagaa atgtcttcaa ttctaagttg aataaaatct tatttgcggt catctttctc
    10321 ttgattttgc ttgttttagc aatgaaactt ttgtaataga aaaggaattg aaatgaaaat
    10381 aggaattatt gctgctatgc cagaagaact ggcttatctg gtccagcatt tagataatac
    10441 ccaggagcaa gttgttttgg ggaataccta tcatacagga accattgctt ctcatgaagt
    10501 cgttcttgta gaaagtggaa ttggtaaggt catgtctgct atgagtgtgg cgattttggc
    10561 tgatcatttc caggtggatg cccttattaa tacgggttca gctggggcag tagcagaagg
    10621 tatcgctgtt ggggatgtcg tgattgctga caaattagcc tatcatgacg tggatgtcac
    10681 agcttttggc tatgcttatg gacaaatggc gcaacaaccg ctttatttcg aatcagacaa
    10741 aacctttgtt gctcaaatcc aagagagttt atctcaattg gaccaaaact ggcatcttgg
    10801 tttgattgct acaggagata gttttgttgc aggaaatgac aagatagaag cgattaagtc
    10861 ccatttccca gaagttttag ccgtggagat ggagggggca gctattgctc aagcagcgca
    10921 tgccctcaat ctcccagtct tagtcatcag agctatgagt gacaatgcca accatgaagc
    10981 aaacatcttt tttgatgagt ttattatcga agctggacgt cgctctgccc aagtcttgtt
    11041 gacctttttg aaggctttag attaagcgga aatttgacag tttttctagc ttatgataag
    11101 atttaagtaa agaaaagcta gaaaacgttt cagaggatat tatgagtatt gaaatgaccg
    11161 tcagtgagat tgcagaggtc ttaggattat ctcgccaagc aatcaataac cgtgtcaaag
    11221 aattaccaga agaagacaca gataaaaatg acaaaggggt aacagttgtt accagaagtg
    11281 gcttgattaa gctagaagaa atctataaaa aaacgatttt tgaagatgag cctgtcagtg
    11341 aagatgtcaa acaacgtgaa ctgatggaga ttctagtgga tgagaagaat gcagaaattc
    11401 ttcgtcttta tgaacaatta aaagccaagg atcgtcagtt atcagaaaaa gacgagcaga
    11461 tgcgtatcaa agaccgtcag attgctgaga aagacaaaca attagatcag caacaacaat
    11521 tgacccttca agccatgaag gatcaagaaa atcttaagct agagctggac caagcaaaag
    11581 aagaagtcca atccactaag aaaggctttt ttgctcgttt atttggagga taatcaagga
    11641 gctgtttagg ttaaatgcta acctgatggc ttcttttgtt tgtgaatagt atagttgatt
    11701 agaacagaga cagtagagga gaggtacaga atggaacgat tagaagatta cattgctttt
    11761 gacttagaat ttaatcagca cgaaggacaa acacacttga ttcaagtatc ggcagtgcgt
    11821 tttagagatg gtcgggaaat cgatgcctat gattcctatg ttcataccag cgtccctcta
    11881 aaaagcttta tcaatggttt gaccgggatt acagctgaga ccttaaaaga tgctcctcca
    11941 gttgagaaag tcttagaaga attccaagag tttgtgggtt ctttgctgat gataggctac
    12001 aatgctgcta aaagtgattt acctatttta gcagagcatg gtttagacta tagccaacag
    12061 tacaaggtgg atttgtatga tgaagctttt gaacgtcgga gttcagattt acatggtatt
    12121 gccaatctca aattgcaaac tgttgcctca tttcttggat ttcaaggtca gtctcataat
    12181 agtttagagg atgctcggat gacggcgcgt gtttacgaat ccttcttaga gtcggatcaa
    12241 gctagggaat tgttagagac agaaagtagc ttatcaaaca atccttttgg tgtcttggac
    12301 ttgtctcaat tatttgacta ggagtgccta tgaaacctga aaaacctaaa aaattgggtc
    12361 ttaaacagat ttacctcaat cttgataaaa tcctctttct atttttcttg atttttatga
    12421 tagtggagta tttgtgggta ccattcaatt catggttggc tagcttctta ttagatcaga
    12481 caggttatct ttttatttcc tataacaatg tcttagccat ccttactcat tctccattga
    12541 ttagtctagc ttttttagcc ttgattgtaa ttaaccttct ggttgcttat tttcaaatag
    12601 gactcctctt tattggtgct cgtcatctcc tctataatga aaagcgaagg ctaattgagt
    12661 atatccgcaa ggttttccat gaaagttttg gatttatgaa aaagctaact tgcgctaaag
    12721 ccttgtttat ctttttctat atagctatgc tttttccttt tatacggaaa atgctgaaga
    12781 tttattatct taataaaatc gtcattccag agtttatcca agcttattta gaagataaat
    12841 attggatgtg gtggctgagc atcctacttc tatctcttat ctttctctat gtctctgtca
    12901 gattgatgtt tgcccttccg aagattgtat atgatcagct gactgttcga gaagcagtga
    12961 tgtttagctt ggagaaaacc aagaagagag ttacttttta tgcttggaat ttattttaca
    13021 tcttgctcaa agcacattta ttattttatc ttcctttgat tcctttatta ttggctcaaa
    13081 ctttggtaga tgatatcact cagagagagt ctctgattct tggtattttg aattttgtcg
    13141 tgattaaaaa tctctattat atggctctga cttatttttt ggttaaattt gtttcatttt
    13201 tgacaggaaa ggagctggat atgcttccta ggagagaaaa agatcacatc gtgcgatggg
    13261 gtgtcatgac ttgtgccagt cttttctttg ccttagaagg ttatatttat ctggaggctc
    13321 ccatggttca tctacctcaa cttatttctc accgaggggt ttccaatgca aatgggattc
    13381 aaaatacagt agagtccttg gaaactacag cacaactcaa accagacttg gtggagacgg
    13441 acgtgcagga aacaaaagat gggcagtttg tcatgatgca tgatgctaac ttgaaaaatc
    13501 tagcaggtat caataaaagt cctcaagact taaacttgga ggagcttaaa gggattgata
    13561 tttttgaaaa tggctaccag actaaaattt caagctttga agattatctc agtcgagcca
    13621 acgaacttgg tcaaaaatta ctaattgaaa ttaaaaccag taaaaaagat agtccagaca
    13681 tgatgaaccg ctttttagcc cgttatgctg caaagctcaa gatttatgga catcaaatcc
    13741 agtctttaga ctaccatgtt gtcgaaaaag taagacagta tgatgccgaa ctgccagttt
    13801 atttcatcat gccctacaat tctgtctttc ctaaaacaag agcgacagga tatactatgg
    13861 agtactcaac cttggatgaa tattttgtaa gcaaactatg gacaacggat cagaaacttt
    13921 atgtctggac tgtcaatgat tcagaagcta tcagcaaatc tcttcactta ggagtagatg
    13981 gagtgattac agatgatttg gaaaaagttc agcgggaaat agaagtagcc caagaagatc
    14041 cagaatatac ggatttgctc ttgaaaaaag cattggaatt ctttgaattt tagtaataaa
    14101 aaagaggaac ggttgttcct cccatgatag gtaagtattc ttgtgaatgc ttgctttttt
    14161 gtggttgcaa tccgtttacg agaattgttt gtattgttct tgtttcaatt tactttatag
    14221 tgctttgaag ttggaatgct acactataac ttctaaaata tagtaaaatg aaccaaaaat
    14281 agtacacaat gtggtataat cttcttatgg catattcaat agattttcgt aaaaaagttc
    14341 tctcttattg tgagcgaaca ggtagtataa cagaagcatc atacgttttc caaatctcac
    14401 gtaatactat ttatggctgg ttaaagctaa aagagaaaac aggagagcta aaccaccaag
    14461 taaaaggaac aaaaccaaga aaaagtagcc ttatttctta agaattttaa tagtttaaag
    14521 cacctagcac ctgtttagat tgacgaaaca ggattcgata cttattttta tcgagaatat
    14581 ggtcgctcat taaaaggtca gttaagaaga ggcaaagtat ctggaagaag atatcagaga
    14641 atttctttgg ttgcaggtct aacaaatgaa tggtgagtta atcgctccaa tgacttacga
    14701 agagacgatg acgagcgact tttttgaagt atggtttcag aaatttctct taccaacatt
    14761 aaccacacca tcggttatta tagtaaaatg gaataagaac aggacaaatc gatcaggaca
    14821 gtaaaatcga attctaacaa tgttttagaa gtctatatgt actattctag tttcaatata
    14881 ccataactgc tcctagtcaa cctgcaagtc ctgtcccagc tccaagctca gctccgactc
    14941 aagatcctag agtggtagca agcgcttcgg ctagctcaac gagcacacaa gctcaagagc
    15001 aagttgacaa gtctgaactt cgtgccttga gtcaagagtt agaccaacgc ttgaaagctt
    15061 tggcaacagt atctgatcca aaaatcgatg caaccaaggc tgtcctccta gatgctcaaa
    15121 aagctccgga agatagtgcc ttgacagagt aaggtctgca tactgcagta gagtctgtga
    15181 aggctgcctt ggactctctc aaagatgtga aagcaaatgc tagcgacagc aagcctgcac
    15241 aggacaagaa ggatgcaaaa caaggaacgg aagatagtaa ggattcagat aagatgactg
    15301 aaacaaactc agttccggca ggagtgattg tggtcagtct acttgccctc ctaggcgtga
    15361 ttgccttctg gctgattcgc cgtaagaaag agtcagaaat ccagcaatta agcacggaat
    15421 tgatcaaggt tctaggacag ctagatgcag aaaaagcgga taaaaaagtc cttgccaaag
    15481 cccaaaacct tctccaagaa acccttgatt tcgtgaaaga agaaaatggc tcagcagaga
    15541 cagaaactaa actagtagag gagcttaaag caatccttga caaactcaag taaaacatga
    15601 tttatgaaat gtcagaccta aaagacattt tcgttcacaa aagcagtgac gagtaatcct
    15661 tgtcgttgct ttttggctat tttgggggat aagatccgcc ttgactagca aaagaaaaga
    15721 ttggtccaat agtgcccgat acgattttgc gtagcagaaa gcttacaaat aaaattgaat
    15781 atagtaaaat aggattagaa ttattaagaa agttggttct ttattggaaa cgatagtatt
    15841 tttaatctct gtttttctag caggtgtttt atcctttttt tctccttgta tttttcctct
    15901 tctgccagtc tatgctggga ttttattgga tgatcaagaa agtgcaaaaa gcttttcttt
    15961 gtttgggaga aaggttctct ggtcaggctt gattcgaaca ctttgcttta tcgctggtat
    16021 ctctctcatt ttctttattc taggctttgg tgctggttac tttggtcata ttctctatgc
    16081 aaattggttt cgatatgtca tgggagctat tattatcatt ttgggtcttc accagatgga
    16141 aatttttcat ttgaagaaat tagaagttca aaaaagtttt acctttaaaa aatcagattc
    16201 taatcgttat tggtcagctt ttttacttgg tattaccttt agctttggtt ggacaccttg
    16261 tattggtcca gttttaagtt ctgttttagc acttgcggct tctggaggca atggtgcttg
    16321 gcaaggagcg atttatactc tcatttacac tctgggcatg gcccttcctt tcttggtctt
    16381 ggcactagct tcaggtctag tcatgccata ttttagtaaa atcaagcgtc atatgatgct
    16441 actaaagaaa attggtggtt tcctcattgt tttaatggga attttgttac tattaggaca
    16501 agtaaatgtt ctagctggaa tttttgaata aaggaggaca aatgaaaaaa gtaatgtttg
    16561 ctggcttaag tctcttgtca ttagttgtat tgatggcctg tggtgaggaa gaaactaaaa
    16621 agactcaagc agcacaacag ccaaaacaac aaacgactgt acaacaaatt gctgttggaa
    16681 aagatgctcc agacttcaca ttgcaatcca tggatggcaa agaagttaag ttatctgatt
    16741 ttaagggtaa aaaggtttac ttgaagtttt gggcttcatg gtgtggtcca tgcaagaaaa
    16801 gtatgccaga gttgatggaa ctagcggcga aaccagatcg tgatttcgaa attcttactg
    16861 tcattgcacc aggaattcaa ggtgaaaaaa ctgttgagca attcccacaa tggttccagg
    16921 aacaaggata taaggatatc ccagttcttt atgataccaa agcaaccacc ttccaagctt
    16981 atcaaattcg aagcattcct acagaatatt taattgatag ccaaggaaag attggaaaga
    17041 ttcaatttgg tgctatcagt aatgcggatg cagaagcagc atttaaagaa atgaactaga
    17101 atcgataaaa tctgattaca agatgtagtc agattttttt agaaaaacat tttataaata
    17161 ttcacatatc tcctatattt atggtaaaat agaattatca gtttattttg gagtcaaaga
    17221 tgaatatatt tagaacaaag aatgttagtt tagataaaac agagatgcat aggcatttga
    17281 agttatggga tttgattttg ctgggtatcg gagccatggt agggacaggc gtctttacaa
    17341 tcacaggtac tgcagctgca acacttgctg gcccagccct agtgatttca atcgttattt
    17401 ctgccttgtg tgtgggatta tcagccctct tttttgcaga atttgcctcg cgagtacccg
    17461 ctacaggagg tgcctatagt tacctctatg ctatcttagg agaattccct tcctggttgg
    17521 ctggttggtt aaccatgatg gagttcatga cagccatatc aggcgtagct tcgggttggg
    17581 cagcttattt taaaggcttg ctctctcaat acgggatagc ctttcctcag gctttaaatg
    17641 gtacctttaa tcctcaagca gggacatttg ttgatttatt gcctattctt gtcttggtct
    17701 tggtgacttc gcttgtttta ctaaatgcca aggcagcctt acgctttaat tcgattctag
    17761 ttattttgaa attttccgct ttagctctct ttgttttagt aggaatttgg aatattaagt
    17821 ttgataattg gagcaatttt gctccttacg gttttggaca aatctatgga gctagcactg
    17881 gtattatggc tggtgcgtcc ttgatgttct tcggtttttt gggatttgaa tccatctcta
    17941 tggctgtaga tgaagtcaag actcctcaaa aaaatattcc tagagggatt gtcttatcgc
    18001 tttctatcgt aaccattctc tatgccttgg tgacccttgt tttgactggt gtggttcact
    18061 atagtcattt aaatgtcgat gatgccgttg cctttgccct tcgtagtgtt gggattagtt
    18121 gggcagccaa ctatgtgtca ttagtggcta tcttgacctt gattacagtt tgtatttcga
    18181 tgacctatgc cctatcgcgt atgatttaca gtttagcacg tgacggctta gtgcctgctg
    18241 cctttaagga actgacgaag actagcaaga taccaaagaa tgctactatc ttgacaggtc
    18301 tagcttcagc agtagcagca ggaatgttcc cactagccag tattgcagcc tttttaaata
    18361 tttgtacctt agcctacttg atcatgctgg cttatggtct gattcgctta cggaaagaaa
    18421 aaggaatgcc caaagctggg gaatttaaaa caccattggt acctctgtta ccaattttat
    18481 cgatcatcat ttgtttatcc ttcatgttac agtataatat gaacacctgg attgctttcc
    18541 tagttgcgtt gttagtagga agtattattt acttcactta tggctataag cattctacca
    18601 tagaagaata aagtgaaagt ctattgagtt gttgacactc agtagatttt tatatgtgaa
    18661 agaaatttca aattttttct aaaaatatct tgacagatta aattttcagg agtagaatat
    18721 ttactagtta attaaatggt taaggagttg ttcatgaaga aacaaaattt atttttagtc
    18781 ctgttaagtg tctttctttt gtgtttgggg gcttgtggtc aaaaggaaag tcagacagga
    18841 aaggggatga aaattgtgac cagtttttat cctatctacg ctatggttaa ggaagtatct
    18901 ggtgacttga atgatgttcg gatgattcag tcaagtagtg ggattcactc ctttgaacct
    18961 tcggcaaatg atatcgcagc catctatgat gcagatgtct ttgtttacca ttctcataca
    19021 ctcgaatctt gggcaggaag tctggatcca aatctaaaaa aatccaaagt gaaggtctta
    19081 gaggcttctg agggaatgac cttggaacgt gtccctggac tagaggatgt ggaagcaggg
    19141 gatggagttg atgaaaaaac gctctatgac cctcacacat ggctagatcc tgaaaaagct
    19201 ggagaagaag cccaaattat cgctgataaa ctttcagagg tggatagtga gcataaagag
    19261 acttatcaaa aaaatgcgca agcctttatc aaaaaagctc aggaattgac taagaaattc
    19321 caaccaaaat ttgaaaaagc gactcagaaa acatttgtaa cacaacatac agccttttct
    19381 tatctagcga agagatttgg gcttaatcaa cttggtattg caggtatctc tcctgaacaa
    19441 gaaccaagtc cacgacaact aacagaaatt caggaatttg ttaagaccta taaggttaaa
    19501 acgattttta cagaaagtaa cgcttcttca aaagtagctg aaactcttgt caaatcaaca
    19561 ggtgtgggtc ttaaaactct gaatccttta gagtcagacc cacaaaatga caagacctat
    19621 ttagaaaatc ttgaagaaaa tatgagtatt ctagcagaag aattaaagtg aggaaagaat
    19681 gaaaatcaat aaaaaatatc tagcaggttc agtggcagtc cttgccctaa gtgtttgttc
    19741 ctatgaactt ggtcgtcacc aagctggtca ggttaagaaa gagtctaatc gagtttctta
    19801 tatagatggt gatcaggctg gtcaaaaggc agaaaatttg acaccagatg aagtcagtaa
    19861 gagagagggg atcaacgccg aacaaattgt tatcaagatt acggatcaag gttatgtgac
    19921 ctctcatgga gaccattatc attactataa tggcaaggtt ccttatgatg ccatcatcag
    19981 tgaagaactt ctcatgaaag atccgaatta tcagttgaag gattcagaca ttgtcaatga
    20041 aatcaagggt ggctatgtga ttaaggtaga cggaaaatac tatgtttacc ttaaagatgc
    20101 agcccatgcg gacaatattc ggacaaaaga agagattaaa cgtcagaagc aggaacgcag
    20161 tcataatcac aactcaagag cagataatgc tgttgctgca gccagagccc aaggacgtta
    20221 tacaacggat gatgggtata tcttcaatgc atctgatatc attgaggaca cgggtgatgc
    20281 ttatattgtc cctcacggca atcacttcca ctatattcct aagagtgatt tgtctgccag
    20341 tgaattagct gctgcccaag cctattggaa tgggaagcag ggatctcgtc cttcttcaag
    20401 ttctagtcat aatgcaaatc cagctcaacc aagattgtca gagaaccaca atctgactgt
    20461 cactccaact tatcatcaaa atcaagggga aaacatttca agccttttac gtgaattgta
    20521 tgctaaaccc ttatcagaac gccatgtaga atctgatggc ctagtatttg atccggcaca
    20581 aataacatat cgtacagtca atggtgttgc tgtaccgcac ggagaccatt atcactttat
    20641 tccttattca caactgtcac ctttggaaga aaaattggct cgtatgattg ctgttaaggg
    20701 acaaaatggt gcagtcttgc caggaatgca ttatttgaaa ccagcaccaa aaccgcaagt
    20761 tcaaccatca actgagaaaa aacaaactga ttttgcagta gaacaggttg ttagaaaagt
    20821 tggagaaggc tatgttgtgg aaattgctgg tgtcagtcac tatgtttttg ctaaagactt
    20881 ggctaaggat aagattgatg ctattgaaaa tctcttgtct aagaaaactc aagagacaca
    20941 tgctctagtt gctaaaaaag aaaatgtcgc tcctcgtgac caagaatttt atgataaagc
    21001 ttacaatctg ttaacccagg ctcataaagt cttgtctgaa aataaaggtc gtacttctga
    21061 tttccaagcc ttagacaaat tagcagaacg cttgaataat gaatcttcta ataaagtaaa
    21121 attggtagat gatttattgg cattcctagc accaattacc cacccagaac gccttgg
//
LOCUS       DAVBCA010000037        20834 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.037, whole genome shotgun sequence.
ACCESSION   DAVBCA010000037 DAVBCA010000000
VERSION     DAVBCA010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20834)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20834)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20834
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.037"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..128
                     /locus_tag="VQU19_001323"
     CDS             <1..128
                     /locus_tag="VQU19_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HET2480567.1"
                     /translation="FRSLENLEQAIVDYIDYYNNKRIKVKLKELSPVQYRTKSFG"
     gene            complement(176..2719)
                     /locus_tag="VQU19_001324"
     CDS             complement(176..2719)
                     /locus_tag="VQU19_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HET2480568.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLFPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVAGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQKKVD
                     ILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTKTFT
                     EAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQAQT
                     GFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(2781..4403)
                     /locus_tag="VQU19_001325"
     CDS             complement(2781..4403)
                     /locus_tag="VQU19_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2480569.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            4609..5634
                     /gene="trpS"
                     /locus_tag="VQU19_001326"
     CDS             4609..5634
                     /gene="trpS"
                     /locus_tag="VQU19_001326"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HET2480570.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            5787..7265
                     /gene="guaB"
                     /locus_tag="VQU19_001327"
     CDS             5787..7265
                     /gene="guaB"
                     /locus_tag="VQU19_001327"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HET2480571.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(7316..8413)
                     /gene="recF"
                     /locus_tag="VQU19_001328"
     CDS             complement(7316..8413)
                     /gene="recF"
                     /locus_tag="VQU19_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HET2480572.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSAQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKAAVNGN"
     gene            complement(8416..8784)
                     /gene="yaaA"
                     /locus_tag="VQU19_001329"
     CDS             complement(8416..8784)
                     /gene="yaaA"
                     /locus_tag="VQU19_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HET2480573.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKIDIPDMNIDILLTQSTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            8943..10193
                     /locus_tag="VQU19_001330"
     CDS             8943..10193
                     /locus_tag="VQU19_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HET2480574.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPVVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSYLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHCPSKYGDEKHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSQLDLFSGFLRMYAGIDRENRNQARKMMNNQLLDL
                     KKGYFTELELEQTKEMIRRSLLLSQDNQSSLIERAYQNALLGKSSADFKSWIAKLEQV
                     DKDAICRAANNVKLQAIYFMEGIE"
     gene            10190..11473
                     /locus_tag="VQU19_001331"
     CDS             10190..11473
                     /locus_tag="VQU19_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HET2480575.1"
                     /translation="MTKVVFEEKYYPAVKEMVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTLVTEVDGDVKQYPAGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELITSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKLTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEITSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            11515..12336
                     /locus_tag="VQU19_001332"
     CDS             11515..12336
                     /locus_tag="VQU19_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET2480576.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            12347..12892
                     /gene="pgsA"
                     /locus_tag="VQU19_001333"
     CDS             12347..12892
                     /gene="pgsA"
                     /locus_tag="VQU19_001333"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HET2480577.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            12889..13716
                     /locus_tag="VQU19_001334"
     CDS             12889..13716
                     /locus_tag="VQU19_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HET2480578.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            13701..14540
                     /locus_tag="VQU19_001335"
     CDS             13701..14540
                     /locus_tag="VQU19_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HET2480579.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPNQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            14533..15327
                     /locus_tag="VQU19_001336"
     CDS             14533..15327
                     /locus_tag="VQU19_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET2480580.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            15386..16204
                     /gene="mreC"
                     /locus_tag="VQU19_001337"
     CDS             15386..16204
                     /gene="mreC"
                     /locus_tag="VQU19_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HET2480581.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKVSQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            16204..16698
                     /gene="mreD"
                     /locus_tag="VQU19_001338"
     CDS             16204..16698
                     /gene="mreD"
                     /locus_tag="VQU19_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HET2480582.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            16792..17970
                     /locus_tag="VQU19_001339"
     CDS             16792..17970
                     /locus_tag="VQU19_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HET2480583.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            18194..18973
                     /gene="rpsB"
                     /locus_tag="VQU19_001340"
     CDS             18194..18973
                     /gene="rpsB"
                     /locus_tag="VQU19_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HET2480584.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            19052..20092
                     /locus_tag="VQU19_001341"
     CDS             19052..20092
                     /locus_tag="VQU19_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HET2480585.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            20339..20680
                     /gene="tnpB"
                     /locus_tag="VQU19_001342"
                     /pseudo
     CDS             20339..20680
                     /gene="tnpB"
                     /locus_tag="VQU19_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
BASE COUNT         6638 a         3335 c         4290 g         6571 t
ORIGIN      
        1 gctttagatc tttagaaaac cttgaacaag ctattgtgga ctacattgat tactacaaca
       61 acaaacgaat taaggtaaaa ctaaaagaac ttagccctgt gcaatacaga actaaatcct
      121 tcggataaat taattgtcta actttttggg gtcagtacat taactggtcg attttttatg
      181 ccttagatga ctttcgtctg tgattataga ttccaaatag taagagagaa gtaaaggaac
      241 agattgctcc agtaataaaa ccattgggaa tgaaggaaag tgtaatagtt cctttcccct
      301 tgggaatgtc aactttcata aatccagttt gagcttgttt aatttctatt ttcttaccat
      361 cttggtaggc agaccaacct ttgtcataag gaatggtgaa gaaaatagat gtatcttgtt
      421 ggacatcata tgtagcaaaa accttgtttt tagaagttga tactgtgaca ggttgttctt
      481 taattttttg aattgcctcg gtgaaagttt tggtatctaa acgatagaag gtaggagatt
      541 caaatgatac ttgtgaattt ccagggaaac taacattgat attgaaagtt tttttctctt
      601 tagtatatcc tagattaaag aaggagaaga cattatcagt tgtaaaagtc tttttttcac
      661 catttacaag gatgtcaacc ttcttttgtt tatcgttaga aaagtgaagg tttatgaaag
      721 agagataaac ttggctgttt tctggaactt caatttgata ctggattgct gcatcttcat
      781 ttgaagaact tgtgacacta atcaaatcat tagtattttc tgttttttca taaggtattg
      841 gagaaaaata atcaaaattg acgttagcaa gttgatttaa aaatgaggcc tgattatcca
      901 aggtatgttc attgaacttg acatcattgt aaacagattg actagcaact gcaatcggaa
      961 gagagtattg attttcatat agggtaagat tatctttttg atagatatct ttaaagccat
     1021 acttatcaat aggactgtct gagatattgt actggatacc aaataaacta tcagccaaaa
     1081 tactattatt tgcatatcgg agattgagat tagtcccaga ggatttaaaa ccaagtttat
     1141 ctaaagtaga gcttgatgaa cgatttcgaa cagatgaaaa ttgagagatt ccattgtagt
     1201 tgaatttcat actgtcattt cctgtctgag tttgtagttt ttcagtacga gtaaattgat
     1261 ttccaatata tgttgagaaa gattccatag ctgggatatc tcgactataa gcacttcgag
     1321 aagcaaatcc ccattcctta gcaattccgt ccatttgaga tgaagcattt aaactcattt
     1381 caaccagtat aaataaagag attagaatgg caaatagatt cacagatata aactttttga
     1441 taactgcaag gagtaaaaga gaatagacaa ccaaaaattc aagagtaagc agaatattca
     1501 aatctgttaa aaaagaataa tgcgatttta gatagatggt agctaaaaat cctgctacta
     1561 caagaaaaag cgaaactaaa aaattccaga ctttaagttc tttcagacgc tttaagactt
     1621 ctgctgctgt gtaaattaac aaggtagaga aaatccaagc atagcgatgt aaaaacatgt
     1681 ttggagtatg catgccttgc caaaataagt caagagcttc tatgtaaaag cttgcaatta
     1741 gaaatgcaaa gaatattaca tatatgagtt tcacgtgaaa cttaatagat ttcagcgtaa
     1801 aaaataaaat ggtcaaaata aagggaaata gtccaacaaa aatcattggg atggccccat
     1861 actttgttgt gtcaaaggaa ccaatgaatt gcttagcaaa gagatcaaga taccagctac
     1921 tttcagtttg aaactttgta acttcagtca atttttcccc atgtgtctgt aaatcaaata
     1981 gagtgggaag agtcataatc aaactagcca taccagctaa aaaggagata actatgaaat
     2041 caagaacaga tgattttcga gtcttaaagt cccacgaaat ttgacagaga taccagaaaa
     2101 taagaaacaa tactgtcata tatccaaaat aataattttg aataaataag attgacagac
     2161 ttgtaaagta caataggagt ttcttttcag ttatcagtag atgtaaacca gttataatta
     2221 aaggaatcaa gataaaaaca tctagccagg tttttatctc taattgactg acagtgaaac
     2281 tcatcagagc ataggaagta gataaggcta gttttaaagt ctgagggata gattgaaaca
     2341 atttattcaa actaaaaaag gttgacagac caatcaatcc aaattttaag agagtggtca
     2401 gatagacagc atctggcata ttcgttagat caaaaaagta aactagaggc gcgagaaaac
     2461 tacccaagta ataactagat agggcataga agtttagccc tagaccactt gtaaaggtgt
     2521 aaaacagact actatttcca tgtaggatat ttcgtaaggc tacatcaaaa ataacgtatt
     2581 gatgaaagcc atctcctaat agaggagagt tgtcgctatt ccagtagata ccttgagata
     2641 gatatactcc agacataatc actacaggaa tgatgaaaga aataaaatag gttcgatatg
     2701 tttttaaaaa tgatttcatg ttacctcgta gaatgataga aaactcagtt ggttaaccca
     2761 actgagtttt gaagttttat ttagtctttc caaagttctt taacttttgc ttgtacttct
     2821 gcattttcta ggaattcatc gtaggtttca tcgatacggt caatgacgcc atttttagat
     2881 aagacaatga tatggttagc caaagtttga ataaactcgt ggtcatggct ggcaaagatg
     2941 attgattctt taaagttttt cagtccatca ttcaagcttg agatagattc caagtccaag
     3001 tgatttgttg gatcatcaag tacaaggaca tttgatttta agagcatgag ttttgaaagc
     3061 atgacacgaa ctttttctcc ccctgacaag acatttacag gtttgttaac ttcatctcca
     3121 gagaagagca tacggccgag gaaaccacgt aggaaagtat tgtcatcttc ttctttactt
     3181 gcgaattgac gcaaccagtc aagaattgat tctcctcctg caaaatcagc tgagttatct
     3241 tttggtaggt aagattgact agttgtaact ccccacttga cagttccttc atagtcaata
     3301 tctcccatga ttgcacgaat taatgcagtc gtttgaatat cattttgtcc aataagtgct
     3361 gtcttatcat ctggacgcaa gatgaaacta atattatcca agatagtttc accatcaatc
     3421 tttacagtta gattttctac tgtcaagaga tcattaccaa tctcacgttc cgctttaaag
     3481 ttgataaatg gatatttacg actagatggt acaatctctt ctagctcaat cttatcaagc
     3541 attttcttac gtgatgttgc ctgccttgac ttagaagcat tggcagagaa acgagcaacg
     3601 aattcttgca attgtttaat tttttcttct gctttagcat tacggtctgc tagcaattta
     3661 gcagcaagct cagaagattc cttccagaag tcgtagtttc cgacatagag tttgattttt
     3721 ccaaagtcaa ggtcggccat gtgagtacaa actttgttta agaagtgacg gtcgtgggat
     3781 actacgataa ctgtgttatc aaagtcaatc aagaagtctt ctaaccaagt aatcgattgg
     3841 atatccaaac cgttagtagg ctcgtccaag agaagaacat ctggtttacc aaaaagtgct
     3901 ttggcgagga gaacctttac tttttcaccg ttggccaatt cgctcatgtt ttggtagtgt
     3961 aattcttctg gaatgtttag gttttgaagt agttgagagg cttcactctc tgcttcccaa
     4021 cctccaagtt cggcaaactc tccttcgagt tcggcagcac gaaccccgtc ctcgtctgag
     4081 aaatcttcct tcatgtagat agcatctttc tctttcatga tgctataaag tttttcattt
     4141 cccatgataa cgacatcaat ggcacgttca tcttcgtagt caaagtgatt ttgacgaaga
     4201 acagagagac gttcatctgg accaagagag atgtgaccag tagtaggttc gatatctcca
     4261 gctaaaattt ttaaaaaggt tgattttccg gcaccattag caccgattaa tccgtaagta
     4321 tttccttctg taaatttgat attgacatca tcaaaaagtt tgcgatcact aaaacgtagt
     4381 gaaacatcag atactgtaag caatgttttt ctcctatatg tgtaatatat ttattctact
     4441 agaaaataca gaaatattca aatttttatt tgtcaatttt gtgtaaatta tatttacagt
     4501 atcctttaca caaatctgta aaaagcaagg ctgatttatt ttgataaatt acggttattt
     4561 cattaaaaaa atgctataat tgaaaggact atatcgaagg agaacaaaat gactaaaccc
     4621 attattttaa caggagaccg tccaacagga aaattgcata ttggacatta tgttggaagt
     4681 ctcaaaaatc gagtattatt acaggaagag gataagtatg atatgtttgt gttcttggct
     4741 gaccaacaag ccttgacaga tcatgccaaa gatcctcaaa ccattgtaga gtctatcgga
     4801 aatgtggctt tggattatct tgcagttgga ttggatccaa ataagtcaac tatttttatt
     4861 caaagccaga ttccagagtt ggctgagttg tctatgtatt atatgaatct agtttcgtta
     4921 gcacgtttgg agcgaaatcc aacagtcaag acagagattt ctcagaaagg atttggagaa
     4981 agcattccga caggattctt ggtctatcca atcgctcaag cagctgatat cacagctttc
     5041 aaggctaatt atgttcctgt tgggacagat cagaaaccaa tgattgagca aactcgtgaa
     5101 attgttcgtt cttttaacaa tgcatataac tgtgatgtct tggtagagcc ggaaggtatt
     5161 tatccagaaa atgagagagc agggcgtttg cctggtttag atggaaatgc taaaatgtct
     5221 aaatcactaa ataatggtat ttatttagct gatgatgcgg atactttgcg taaaaaagta
     5281 atgagtatgt atacagatcc agatcatatc cgcgttgagg atccaggtaa gattgaggga
     5341 aatatggttt tccattatct agatgttttt ggtcgtccag aagatgctca agaaattgct
     5401 gatatgaaag aacgttatca acgaggtggt cttggtgatg tgaagaccaa gcgttatcta
     5461 cttgaaatat tagaacgtga actgggtcct attcgtgagc gccgtattga atttgctaag
     5521 gatatgggag aagtttataa tatgattcaa aaaggtagtg aaagagcgcg tgaagttgcg
     5581 ggtcaaaccc tatctgaggt aaaaggggca atgggacttc attactttaa ctaagtttat
     5641 tttacaagaa actatcattt ctatctcgaa gaaaagatag tttttttatt tacccctgta
     5701 acatttgaca aatttttata gaatggtatg atagatacaa tataaaaaga gtcaagctca
     5761 aaaagaaaga aaagaggaaa cttcgaatgt ctaattggga cactaaattt ttgaaaaaag
     5821 gttttacctt tgatgatgta ttgcttattc cagctgaaag tcatgtgttg cctaacgatg
     5881 cagatttaac aactaaattg gcagataatt tgactttaaa tatcccaatt attaccgctg
     5941 ccatggacac agttacagag agtcaaatgg ccattgctat tgctcgtgca ggcggtctcg
     6001 gagttatcca taaaaacatg tcaattgctc aacaagcaga cgaggttcgt aaggtaaaac
     6061 gttctgaaaa tggagttatt attgatccgt tcttcttgac gcctgaacat acaattgctg
     6121 aagcagatga gcttatgggt cgttaccgca tcagtggtgt tccagttgtt gaaacacttg
     6181 aaaatcgtaa attggttggt attttgacaa accgagatct tcgttttatt tcagattata
     6241 atcaaccaat ttcaaaccat atgactagtg aaaatcttgt tactgctcct gtgggtacgg
     6301 atcttgcaac ggctgagagt attcttcaag agcatcgtat tgaaaaactt ccgttggtcg
     6361 atgaagaagg cagtctttct ggtttgatca ctatcaaaga tattgaaaaa gttattgagt
     6421 ttccaaatgc ggctaaagat gagtttggtc gtcttctagt tgcaggtgca gtaggtgtta
     6481 cttcagatac atttgaacgt gcagaggctc tttttgaggc aggagcggat gcgattgtta
     6541 ttgatactgc acatggtcat tctgcaggtg tcttgcgtaa aattgccgag attcgtgctc
     6601 atttcccaga tcggactttg attgctggaa atattgctac tgctgaaggt gcacgtgccc
     6661 tttatgaagc gggtgtagac gttgttaagg ttggtattgg accaggttct atctgtacta
     6721 ctcgtgtgat tgctggtgtt ggtgttccgc aagtaacagc tatctacgat gctgcagctg
     6781 ttgcgcgcga atatggtaaa acgattattg ctgacggtgg gatcaagtat tctggagata
     6841 ttgtaaaagc acttgctgca ggtggaaatg ctgttatgct tggatctatg tttgctggaa
     6901 ctgatgaagc tccaggcgaa actgaaatct tccaaggacg taaattcaag acttaccgtg
     6961 gtatgggatc aattgctgct atgaagaaag gttcaagcga ccgttatttc caaggttctg
     7021 tcaatgaagc aaacaagctt gttccagaag gaattgaagg tcgtgttgct tataaaggag
     7081 cggcagctga tattgttttc caaatgattg gtggtattcg ctctggtatg ggttactgtg
     7141 gtgcagctaa ccttaaagaa ctacacgata atgctcaatt tattgaaatg tctggtgctg
     7201 gtttgaaaga aagccatcct catgatgtgc aaattactaa tgaggcacca aattattcta
     7261 tgtaaaaaac aatgaaaaga actccagtga aaacaggagt tcttttacaa tgttgtcaat
     7321 ttccatttac agcagcttta ccatcctgaa tagtgaagat acttagattt tctggcagat
     7381 tttgaagatg gtctaagctt gttgttgtga taaaggtttg gattgattga gaaatcgttt
     7441 ctaataattt taactgtcta gtgttgtcaa gttcactcat cacatcgtca agcagtaata
     7501 taggagattc tgtggtaatg ctttccatta attcgatttc tgctaatttt atcgagagga
     7561 cgagactacg atgttgacct tggcttccga aactagcatc catcccattt atataaaaag
     7621 aaatgtcatc tcgatgagga ccgacaccag tattcttttt aaataaatct ctggatctac
     7681 ttttttctaa agcaattttg aaagattcgg ataagttttg tttgtcagtt atattgacag
     7741 aagattgata ggatattgac aactcttcga tctgattaga gagttcaaaa tgtttcttac
     7801 gcccaaatga ttctagtttt tttatgaaat ctaagcggtg attcattaca cgacatccat
     7861 aatcaactag ctgatcatct aacacagaaa ggaatgtttc atctattttt tgagctgatt
     7921 ttaggtaagt gtttctttgc tttaggatgt ggttataatt ggttaagtca gataaataga
     7981 ttggcttaat ttgcccaagt tccatatcaa tgaattttcg tcgaatcgaa ggtgctcctt
     8041 taattagttg taaatcttca ggagcaaata agacaacatt catgtgtcct acataatctg
     8101 aaaggcgtgc ctgttttaag tgattaactt ttgttacacg gcctttttgt gttagttcga
     8161 tttctagggg aatggatcca gtttttttct gaacgagacc tgaaagatga agttgttcct
     8221 catcaaaatg aatgagattt ttatctgttc gagttcgatg actacgcgtt aaggctaaaa
     8281 aatagatagc ctctaacatg tttgtttttc cttgtgcatt acgtcccaaa aagacattca
     8341 atttaggatt aaagtctatt ttcgtttctt tgtaattacg aaaagtcttg agagatagat
     8401 gttgtagcca catgattatc taccagggaa tcgtggagct tgttggcttt taggtgatga
     8461 agcaggtttc gatttgtctt ttttaactcc cttattcatc tttttgacaa gtttagcgat
     8521 ccgttctttt tcaactttat cagcttggta ttcatcttgt tcttcagaag tagattgtgt
     8581 caacaagatg tcaatgttca tgtcagggat gtcaatttta tcgccaatac gaagtttttt
     8641 accacgacga ctctctaatt ccctattaaa gtaaacagaa tgttcagaga gaaatgattt
     8701 aatagctcct ccgctatgtg taattccaag ttctttgagt agtgcttgga gggtaataaa
     8761 ttcttcaaat aatttgtatt ccataattca cctcaatctt tggtattata ccatattttc
     8821 ctaaaaatag tgagagatac agcgagaaat gtaagcgatt tttatttcaa aagtgttaca
     8881 gggaacaaga aaatttcagg ttttcgtgat ataatagaag tctgtatata aggagataaa
     8941 tcatggagtt agtgcatgga atttcaacac attttatcca atcaaaaaag tttaaaacaa
     9001 acaaaattac cgtgcgtttt accgctccat tatcccttga tacgattgca ggtcacatgt
     9061 tgagtgcaag tatgctagag actgctaatc agatgtaccc cacttctcaa gatttgagga
     9121 gacacttggc cagtctatac ggtacagata tgtcaaccaa ttgtttcaga agagggcaaa
     9181 gccacattat agaattgaca tttacctatg ttcgtgatga gtttttaagt aggaaaaacg
     9241 tgctaacttc tcagattttg gaacttgtaa aagaaactct tttttcaccc gtagtagttg
     9301 ataatgggtt tgatccggcc ttatttgaaa ttgagaaaaa acaattgcta gcaagtttag
     9361 cagctgatat ggatgattct ttttattttg cacataaaga attggataaa ttgttttttc
     9421 atgatgaacg tcttcaattg gaatatagtt atttacgaaa tcgtatttta gctgaaactc
     9481 cacaaagttc ttattcttgt ttccaagaat ttttagccaa tgatcgaata gatttctttt
     9541 tcctaggtga ttttaatgag gttgaaattc aaaatgtatt agaatcattt ggctttaaag
     9601 gtcgaaaagg agatgtgaag gttcagtatt gtcaacctta ttctaatatc cttcaggaag
     9661 gtatggttcg gaaaaatgtg ggacaatcca ttttggaatt aggttatcat tgcccttcta
     9721 aatatggtga tgagaaacat ttacccatga ttgtaatgaa tggtttactt ggtggatttg
     9781 ctcactctaa actttttaca aatgtccgtg aaaatgctgg attagcttat actatttcaa
     9841 gtcagctcga tttatttagt ggattcttga ggatgtatgc tggtattgac cgagaaaatc
     9901 gtaaccaggc tcgtaaaatg atgaataatc aactgcttga tttaaaaaaa ggttatttta
     9961 cagagcttga gttagagcag accaaggaaa tgattcgtcg gtctttgtta ctttctcaag
    10021 ataaccaatc ttcattgatt gaacgtgctt atcaaaatgc cttacttgga aaatcttcag
    10081 cagattttaa aagttggatt gcaaaactcg agcaagttga caaagatgct atttgtagag
    10141 cagctaacaa tgtgaaacta caagcgattt actttatgga aggaatagaa tgacaaaggt
    10201 tgtttttgaa gaaaaatact atccagctgt aaaagaaatg gtttatcgaa ctcgtttggc
    10261 aaatggattg acagtagctc ttttgcctaa aaaggaattt aaagaggttt acgggagtgt
    10321 aactgtacag tttggttcgg tagatacgct tgtcacagaa gttgatggag atgtaaaaca
    10381 atatcctgca ggaattgctc attttcttga acataaatta tttgaaagag aagattctag
    10441 cgatttgatg tcggctttta cgagtctagg tgcagatagt aatgccttta caagctttac
    10501 aaaaacaaac tatctttttt cagcaacgga ttatttttta gaaaatttag atttacttga
    10561 tgaattgata acatcagcac actttactga agcttccatt ctgacagagc aggatattat
    10621 tcagcaagaa cgagaaatgt accaagatga tccagattcg tgtttattct tttcaacttt
    10681 agcgaatttg tatcctggta cacctttagc aactgatata gttggaagtg aggagtccat
    10741 ttcccaaatc aatctaacta atttgcaaga aaattttaca aagttttaca aacctgtaaa
    10801 catgtctctg tttttagttg gtaattttga tgtggagcga gtacaggact attttgaaag
    10861 caaagaactg aaagattcag attttcagga agtagcaaga gaaaagttgt ttttacagcc
    10921 tgtaaagcta acagatagta tgagaatgga agtatcttct cccaaactag cgattggagt
    10981 tagaggtaag cgagaagttt ctgaagcgga ttgctatcga catcatattt tattaaaatt
    11041 attgtttgca atgatgtttg gttggacttc ggatcgtttt caaaaatgtt atgaatcagg
    11101 taaaattgat gcgtccttat ctctggaagt tgaaataaca agtcgctttc attttgtcat
    11161 gttgacaatg gatacgaaag agccagttgc tttgtctcat caatttagga aggctattcg
    11221 taattttaca aaggatttag atattacaga ggaacattta gatattatca aaagagagat
    11281 gtttggcgaa tttttcagta gcatgaactc tcttgaattt attgcaacgc aatatgatgc
    11341 ttttgaaaat ggtgagacaa tttttgattt gccgaaaatt ttacaggaaa ttactttaga
    11401 ggatgtcctt gatgctggac atcatttaat agatgatggt gacatagttg attttacaat
    11461 atttccatcg tagtaaccta tcataataga cactagaaag aagggatgac aagtatgaga
    11521 aaaaaaacaa ttggagaggt tttacgatta gctagaatca atcagggatt gagtttagat
    11581 gaattgcaga aaaagacaga aatccagtta gatatgttgg aagcaatgga agcagacgat
    11641 ttcgatcaac ttccaagtcc tttttacacg cgttctttct tgaaaaaata tgcatgggct
    11701 gttgagttag atgaccaaat tgttttggat gcttatgatt ctgggagtat gattacttat
    11761 gaggaagtag atgttgatga agatgagttg acaggtcgta gacgttcaag taagaaaaag
    11821 aagaaaaaaa catcattttt acctttattt tattttatcc tttttgcttt atcgatttta
    11881 atttttgtga cttattatgt ttggaactat attcaaactc aaccagagga gccttctctt
    11941 tctaattaca gtgtggttca atcaacaagt tcaactagct ctgttcccca ctcctcaagt
    12001 agtagttctt ctagtataga atcagctata agtgtatcag gcgaaggaaa tcatgtagaa
    12061 atcgcttata agacaagtaa ggaaacagtt aaattgcaat tggcagtttc agatgttaca
    12121 agttgggtca gtgtttcaga aagcgaactt gagggcggtg taaccttatc gccaaagaag
    12181 aaaagtgcag aagcaacagt tgcaactaaa agtcctgtaa caattacgtt aggtgttgta
    12241 aaaggtgttg atttgacagt agataatcag actgttgatt tatcgaaatt aacagctcag
    12301 actggacaaa tcactgtaac ctttactaaa aattaaggaa aaacgaatga aaaaagaaca
    12361 aattcccaat ctcttaacaa taggtcgaat tctctttata cctattttta tctttatttt
    12421 aacgatagga aattcgatag agagtcatat agttgcagct attatctttg ctgttgccag
    12481 tattaccgac tatttagatg gatatttagc tcgtaaatgg aatgtggtca gtaattttgg
    12541 taaatttgca gatcctatgg cggataagtt actagttatg tcggctttta ttatgttgat
    12601 tgagttaggt atggctccgg cttggattgt tgcagtgatt atatgtcgtg agttagctgt
    12661 gacaggttta aggcttttat tggttgaaac tggtggaaca attttagcag cagcaatgcc
    12721 tggaaaaatt aaaactttta gtcagatgtt tgctattatt ttcttgctat tacattggac
    12781 tttgcttggt caagttctac tttatgtagc cttatttttc actatctact ctggctatga
    12841 ctattttaag ggtagtgcct atgtatttaa agggacattt ggttcgaaat gaaatcaata
    12901 attgatgtaa aaaatctttc ttttcgctat aaagaaaatc agaactacta cgatgtgaag
    12961 gatattacgt ttcacgtgaa acgtggagaa tggctttcga ttgtagggca taatggtagt
    13021 ggtaaatcaa cgacggttcg attaattgat ggcttactgg aagcagaatc cggagagatt
    13081 gtaattgatg gccaacgttt gactgaggaa aatgtttgga atatacgtcg tcaaatcggt
    13141 atggtttttc aaaatccaga caatcaattt gttggagcga ctgttgaaga tgatgttgct
    13201 tttggtttgg aaaatcaggg actttctcgt caagaaatga aaaagagagt ggaagaagct
    13261 ctggctttag ttggcatgtt ggactttaaa aagagagagc cagcgcgtct atcaggtggt
    13321 caaaagcaac gtgtggccat tgcaggtgtt gtagccctaa gaccagctat tttaatctta
    13381 gatgaagcaa cgagtatgtt ggatcctgag gggcgtagag aacttattgg gacagtaaaa
    13441 ggaattcgaa aagactatga tatgacggtc atttctatta cccatgattt ggaagaagtc
    13501 gccatgagtg atcgcgtatt ggtcatgaaa aaaggggaaa ttgaatcaac tagtagtcca
    13561 agggagcttt tctctcgaaa tgatttagat caaattggat tagacgatcc ttttgctaat
    13621 caattaaaaa aatctttgag ccagaatggc tatgatttac ctgaaaatta tttgacagaa
    13681 agtgagctag aggataagct atgggaattg ctctagaaaa tgtgaatttt acatatcaag
    13741 aaggtactcc cttagcttca gcagctttgt cggatgtttc tttgacgatt gaagatggct
    13801 cttatacagc tttaattggg cacacaggta gtggtaaatc aactatttta caactcttaa
    13861 atggtttatt ggtgccaaat caagggagtg tgagggtttt tgatacctta atcacctcga
    13921 cttctaaaaa taaagatatt cgtcaaatta gaaaacaggt tggcttggta tttcagtttg
    13981 ctgaaaatca gatttttgaa gaaacggttt tgaaggacgt tgcttttgga ccgcaaaatt
    14041 ttggagtttc tgaagaagat gctgtgaaga ctgcgcgtga gaaactggct ctggttggaa
    14101 ttgatgaatc actttttgat cgtagtccgt ttgagctgtc agggggacaa atgagacgtg
    14161 ttgccattgc aggcatactt gccatggagc cagctatatt agtcttagat gagccaacag
    14221 ctggtctaga tcctctaggg agaaaagagt tgatgaccct gttcaaaaaa ctccaccagt
    14281 cagggatgac catcgtcttg gtaacgcatt tgatggatga tgttgctgaa tatgcgaatc
    14341 aagtctatgt aatggaaaag ggacgtttag taaagggggg caaaccaagt gatgtctttc
    14401 aagacgttgt ttttatggaa gaagttcagt tgggagtacc taaaattacg gccttttgta
    14461 aacgattggc tgatagaggc gtgtcattta aacgattacc gattaagata gaggagttca
    14521 aggagtcgct aaatggatag tatgatttta gggcgttata tcccagggga ttcgattgtt
    14581 caccgattgg atccacgtag caaattgctt gctatgatgc tactgatttt gattgtgttt
    14641 tgggctaata accccttgac gaatctgatt ctttttatag cgacagggat atttattgcc
    14701 ttgtcaggag tatctctttc attttttatt cagggcttga agtctatgtt tttcttgatt
    14761 gccttcacaa ctatttttca actatttttc atttctaatg ggaatgtttt atttgagttt
    14821 tcgtttgtga gaatcacgga ttatgctttg caacaagctg ggattatttt ttgtcgcttt
    14881 gtattgatta ttttcttttc aactttgtta accttaacaa ccatgccttt aagtttggca
    14941 tcagctgtcg aagctttatt agcaccttta aagcgtgtga aagttccagt tcatgaaatt
    15001 ggattgatgc tgtctatgag tttgcgtttt gtcccaacct tgatggatga tacgactcgg
    15061 attatgaatg cacagaaagc tcgtggagtg gattttggag aaggaagcat cgttcaaaaa
    15121 gtaaaggcga tgattcccat tttgattcct ctttttgcga caagtttaaa acgtgcagat
    15181 tccttggcta tcgctatgga agcgcgtggc tatcagggtg gaaaaggcag aagtcaatac
    15241 cgacaattga aatggactct aaaggatacg ctgaccattc ttgttattct cgtacttggt
    15301 tgttgtttat ttttcttaaa atcttagtag ctttcaggaa ttgataaaaa gttactgtaa
    15361 cagtttttga tataaaggta ggaatatgaa ccgttttaaa aaatcaaaat atgtcattat
    15421 tgtttttgtc actgttctgc ttgtgtcagc tctcttagcg acgacttatt caagtacaat
    15481 tgtgacaaaa ttaggagatg gaatctcatt ggttgataga gttgtacaaa aaccttttca
    15541 gtggtttgat tctgtcaaat cagatttggc tcatttgaca cgaacatata atgaaaatga
    15601 aagtttgaag aaacagcttt accaattaga agttaaatca aatgaggtgg aaagtttaaa
    15661 gacagaaaat gaacaactgc gccaattgct tgatatgaag tctaaattgc aagccacaaa
    15721 gactttagca gcagatgtta ttatgcgttc tccggtatct tggaagcagg agttgacctt
    15781 agatgcaggt agatcaaaag gtgcttctga gaacatgtta gctattgcaa atggtggctt
    15841 gattgggagt gtttcaaaag tagaggagaa ctctactata gtcaaccttc tgacaaatac
    15901 ggaaaatgct gataagattt ctgttaaaat tcaacatggc tctactacaa tttatggaat
    15961 tattattggc tatgacaagg aaaatgacgt tcttaaagtt agccaattaa atagtaatag
    16021 cgatattagt gcgggagata aggtgactac tggtggatta ggaaacttta acgttgctga
    16081 tattcctgtt ggtgaagtgg ttgccacaac gcatagtaca gactatttga cacgagaagt
    16141 aactgttaaa ttgagtgcag atactcataa tgtagatgtg atagaattag tggggaattc
    16201 ataatgagac agttgaagcg agttggagta tttttattgc ttcctttctt tgttctaatt
    16261 gacgcccata ttagccagct tctgggctca tttttccccc atgtacattt ggctagtcat
    16321 tttctttttc tatttctctt atttgagacg atagaagtat cagagtatct ctacctagtc
    16381 tattgttttg ttataggctt ggtttatgat gtttactttt tccatctaat agggattaca
    16441 actctcttat ttatcttatt gggagccttc cttcataaat tgaatagtgt tattttgttg
    16501 aatcgttgga caagaatgct agctatgatt gtactgacat tcctgtttga aatgggtagt
    16561 tatcttttgg cttttatggt agggttgaca gtagatagca tgtcgatttt tatagtctat
    16621 agcttggtac cgacgatgat tttaaatttt ttatggatta ctgtttttca atttattttt
    16681 gaaaaatatt atctataaga acgacatata aatgtaacaa aggcgtaata tttattaggc
    16741 ctttttttgg tatactagta ttgtctttaa aagaaggagt atctacgtaa tatgaagaaa
    16801 aaaatcttag cgtcactttt attaagtaca gtaatggttt ctcaagtagc tgttttaaca
    16861 actgcgcatg cagaaacgac tgatgacaaa attgctgctc aagataataa aattagtaac
    16921 ttaacagcac aacaacaaga agcccaaaaa caagttgacc aaattcagga gcaagtatca
    16981 gctattcaag ctgagcagtc taacttgcaa gctgaaaatg atagattaca agcagaatct
    17041 aagaaactcg agggtgagat tacagaactt tctaaaaaca ttgtttctcg taaccaatcg
    17101 ttggaaaaac aagctcgtag tgctcaaaca aatggagccg taactagcta tatcaatacc
    17161 attgtaaact caaaatcaat tacagaagct atttcacgtg ttgctgcaat gagtgaaatc
    17221 gtatctgcaa acaacaaaat gttagaacaa caaaaggcag ataaaaaagc tatttctgaa
    17281 aaacaagtag caaataatga tgctatcaat actgtaattg ctaatcaaca aaaattggct
    17341 gatgatgctc aagcattgac tacgaaacag gcagaactaa aagctgctga attaagtctt
    17401 gctgctgaga aagcgacagc tgaaggggaa aaagcaagtc tattagagca aaaagcagca
    17461 gctgaggcag aggctcgtgc agctgcggtg gcagaagcag cttataaaga aaaacgagct
    17521 agccaacaac aatcagtact tgcttcagca aacactaact taacagctca agtgcaagca
    17581 gtatctgaat ctgcagcagc acctgtccgt gcaaaagttc gtccaacata cagtacaaac
    17641 gcttcaagtt atccaattgg agaatgtaca tggggagtaa aaacattggc accttgggct
    17701 ggagactact ggggtaatgg agcacagtgg gctacaagtg cagcagcagc aggtttccgt
    17761 acaggttcaa cacctcaagt tggagcaatt gcatgttgga atgatggtgg atatggtcac
    17821 gtagcggttg ttacagctgt tgaatcaaca acacgtatcc aagtatcaga atcaaattat
    17881 gcaggtaatc gtacaattgg aaatcaccgt ggatggttca atccaacaac aacttctgaa
    17941 ggttttgtta catatattta tgcagattaa tttacagagg gactcgaata gagccctctt
    18001 ttcaggtttt accgtgacaa tccctattaa aaattatatc aaaatagctt gaaaatattg
    18061 gaaaagtatg gtaaaatgaa aattgtcgtg tgaacgataa tactcattct tgatgaattg
    18121 tgaagcagtt gcccttgggt cgttttgcga gttgaagtca agaagaggaa aaaaacaaaa
    18181 aggagaaata ctcatggcag taatttcaat gaaacaactt cttgaggctg gtgtacactt
    18241 tggtcaccaa actcgtcgct ggaatcctaa gatggctaag tacatcttta ctgaacgtaa
    18301 cggaatccat gttatcgact tgcaacaaac tgtaaaatac gctgaccaag catacgactt
    18361 catgcgtgat gcagcagcta acgatgcagt tgtattgttc gttggtacta agaaacaagc
    18421 agctgatgca gttgctgaag aagcagtacg ttcaggtcaa tacttcatca accaccgttg
    18481 gttgggtgga actcttacaa actggggaac aatccaaaaa cgtatcgctc gtttgaaaga
    18541 aattaaacgt atggaagaag atggaacttt cgaagttctt cctaagaaag aagttgcact
    18601 tcttaacaaa caacgtgcgc gtcttgaaaa attcttgggc ggtatcgaag atatgcctcg
    18661 tatcccagat gtgatgtacg tagttgaccc acataaagag caaatcgctg ttaaagaagc
    18721 taaaaaattg ggaatcccag ttgtagcgat ggttgacacc aatactgatc cagatgatat
    18781 cgatgtaatc atcccagcta acgatgacgc tatccgtgct gttaaattga tcacagctaa
    18841 attggctgac gctattatcg aaggacgtca aggtgaggat gcagtagcag ttgaagcaga
    18901 atttgcagct tcagaaactc aagcagattc aattgaagaa atcgttgaag ttgtagaagg
    18961 cgacaacgct taatttatac aaatagtaat tacctaggag ggcggggctt agcccggctc
    19021 tcctattttc aaaaaatata ggagaattaa aatggcagaa attacagcta aacttgtaaa
    19081 agagttgcgt gaaaaatctg gtgccggtgt tatggacgct aaaaaagcgc ttgtagaaac
    19141 agacggtgac atcgaaaaag cgattgaatt gcttcgtgaa aaaggtatgg ctaaggcagc
    19201 taagaaagct gaccgtgttg ctgcagaagg tttgactggt gtttatgtta acggtaatgt
    19261 tgcagcagtt attgaagtaa acgctgaaac tgacttcgtt gcaaaaaacg ctcaattcgt
    19321 tgaattggta aatactacag ctaaagtcat tgctgaagga aaacctgcta acaacgaaga
    19381 agctcttgct ttgataatgc cttcaggtga aactcttgaa gctgcatacg tatctgcaac
    19441 agcaactatc ggagagaaaa tctcattccg tcgctttgca ttgattgaaa aaacagacgc
    19501 acaacacttt ggagcatacc aacataacgg tggacgtatc ggtgttattt cagttgttga
    19561 aggtggagac gaagcacttg ctaaacaatt gtcaatgcac atcgcagcga tgaaaccaac
    19621 agttctttct tacaaagaat tggatgagca attcgttaaa gatgagttgg cacaattgaa
    19681 tcacgttatc gaccaagaca acgaaagccg tgcaatggtt aataaaccag ctcttccaca
    19741 cttgaagtat ggatcaaaag ctcaattaac tgatgatgtt attgctcaag ctgaagctga
    19801 catcaaagct gaattggctg cagaaggcaa accagaaaaa atctgggaca aaattattcc
    19861 aggtaaaatg gatcgcttca tgcttgataa cactaaagtt gaccaagctt acacacttct
    19921 tgcacaagtt tacatcatgg atgacagcaa gacagttgaa gcataccttg aatcagttaa
    19981 cgcttcggta gttgagtttg ctcgctttga agttggtgaa ggtatcgaga aagctgcaaa
    20041 cgacttcgaa gctgaagttg cagctacaat ggcagcagcc ttgaataact aataatagaa
    20101 aggaagcaaa ttgcttcctt ttttgtatag ggcttagatt tttcctgaaa ttgttttttc
    20161 cccagtctca ctcgattaga ataattaaaa caaaaagccc tataataagg gctaagtgca
    20221 tttaggagac tatacttcaa attcatagta agcgcgttca taacaaggta tctatcctaa
    20281 ttccccaact tccagtatac tagataaaaa ataattatcg gagtaaaggt attgtactat
    20341 gataattcaa ctaagtgatt taggtcaagt tcaccttgtt tgtggcaaga cagatatgag
    20401 gtagggaata gactcattag cctatgtagt taaaacccac tttgaattgg attctttctc
    20461 cggtcaagtc tttctctttt gtggtgaacg taaagaccgc tttaaagccc tttactggga
    20521 tggtcaagga ttttggctac tatataaacg ctttgagaac ggaaaactga cttggctaag
    20581 tacagaaaag gatgtcaaag ctctcgcacc tgaacaagta gattggctta tgaagggctt
    20641 ttctatcact ccaaaatata gtatattgaa actagaatag tacacctctg cttctaaaac
    20701 attgttagaa atcgatttga ctgtcctgat cgatttatcc tgttcttatt tcattttact
    20761 ataaatctat cagaaagttg tgatttctat tgaaatgagg actttctttt tacactcatc
    20821 tgctttcaaa aagc
//
LOCUS       DAVBCA010000038        20815 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.038, whole genome shotgun sequence.
ACCESSION   DAVBCA010000038 DAVBCA010000000
VERSION     DAVBCA010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20815)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20815)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20815
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.038"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            182..658
                     /locus_tag="VQU19_001343"
     CDS             182..658
                     /locus_tag="VQU19_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2480586.1"
                     /translation="MKLSLYSEVEHYHFLSSYSLNDITYTDTPKNIIEKSKKDKYRYP
                     IVILNKDHKVIGFFCLHLNTGPKEYGYYQNDYALIRGFSIHDNFRNQGYGSNALNEIF
                     EFIDSTLKLEINHIILAVNEKNILAQKAYRNSGFSVVKKDLEGKRGKLIIMEKSRN"
     gene            complement(1332..1724)
                     /locus_tag="VQU19_001344"
     CDS             complement(1332..1724)
                     /locus_tag="VQU19_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HET2480587.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLTRQIAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTDKSQYEFLFPSVK
                     IKEEKTDKKEEVATDSSEKAEKKIRREA"
     gene            complement(1702..2163)
                     /locus_tag="VQU19_001345"
     CDS             complement(1702..2163)
                     /locus_tag="VQU19_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HET2480588.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLI
                     SEVRYQQQSEQKEWLLFVGQLEAELDRSQFEKVEGNRLYMKQDDKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES"
     gene            complement(2126..2386)
                     /locus_tag="VQU19_001346"
     CDS             complement(2126..2386)
                     /locus_tag="VQU19_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480589.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            complement(2391..2819)
                     /locus_tag="VQU19_001347"
     CDS             complement(2391..2819)
                     /locus_tag="VQU19_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HET2480590.1"
                     /translation="MEGQIVKSMIKAFTMLESLLVLGLVSILALGLSGSVQSTFAAVE
                     EQIFFMEFEELYRETQKRSVASQQKTSLNLDGQMISNGSQKLTVPKGIQAPSGQSITF
                     DRAGGNSSLAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            complement(2788..3114)
                     /locus_tag="VQU19_001348"
     CDS             complement(2788..3114)
                     /locus_tag="VQU19_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HET2480591.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLDKNEDATLSKLQGDGRITEEQVKAYNEYYTKNGGA
                     NRKVND"
     gene            complement(3116..4132)
                     /locus_tag="VQU19_001349"
     CDS             complement(3116..4132)
                     /locus_tag="VQU19_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HET2480592.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSSLLDKQCVTQMRTGLSQGKSFSEMMESLGCSSTIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLDFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            complement(4080..5021)
                     /locus_tag="VQU19_001350"
     CDS             complement(4080..5021)
                     /locus_tag="VQU19_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HET2480593.1"
                     /translation="MVQEIAQEIIRSARKKGTQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAN
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            complement(5097..5462)
                     /locus_tag="VQU19_001351"
     CDS             complement(5097..5462)
                     /locus_tag="VQU19_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HET2480594.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            complement(5613..6671)
                     /locus_tag="VQU19_001352"
     CDS             complement(5613..6671)
                     /locus_tag="VQU19_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HET2480595.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPKKAIKEIYDLTDGRGVDVAIEAVGIPETFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            complement(6834..7985)
                     /gene="nagA"
                     /locus_tag="VQU19_001353"
     CDS             complement(6834..7985)
                     /gene="nagA"
                     /locus_tag="VQU19_001353"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HET2480596.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            complement(8138..9955)
                     /locus_tag="VQU19_001354"
     CDS             complement(8138..9955)
                     /locus_tag="VQU19_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HET2480597.1"
                     /translation="MRIKWFSLIRIIGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNNEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     AGVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMIFLLSATAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPILQTLRPLPYIHAILAAGTGILTFIVCMVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            complement(10056..11198)
                     /gene="tgt"
                     /locus_tag="VQU19_001355"
     CDS             complement(10056..11198)
                     /gene="tgt"
                     /locus_tag="VQU19_001355"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HET2480598.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMLLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAECGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFRKYFVEKYGYNKSGRNF"
     gene            11328..12185
                     /locus_tag="VQU19_001356"
     CDS             11328..12185
                     /locus_tag="VQU19_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HET2480599.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSGFLNP
                     LSRIHGTVLEQPFFSILGQILQTYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQHFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            complement(12213..12857)
                     /gene="pcp"
                     /locus_tag="VQU19_001357"
     CDS             complement(12213..12857)
                     /gene="pcp"
                     /locus_tag="VQU19_001357"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HET2480600.1"
                     /translation="MKVLVTGFEPFGGEKGNPTLEAIKGLPAEIHGAEVRWLEVPTVF
                     HKSAQVLEEEMNRYQPDFVLCIGQAGGRTSVTPERVAINQDDARISDNEDNQPIDRPI
                     RPDGASAYFSSLPIKAMVQAIKKEGLPASVSNTAGTFVCSHLMYQALYLVEKKFPYVK
                     AGFMHIPYMMEQVVNRPTTPTMSLVDIRRGIEAAIGAMIEHGDQELKLVGGETH"
     gene            complement(12964..13332)
                     /locus_tag="VQU19_001358"
     CDS             complement(12964..13332)
                     /locus_tag="VQU19_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HET2480601.1"
                     /translation="MSIITIILTTIVALEHFYIFYLESIATRSDATSRVFNMEKEELA
                     HPSVSSLFKNQGIYKALLGVFLWYGIYFSQNLEIVTIFVLFVIGAATYGSLTADKKII
                     LKQGGSAILALISILLFKYT"
     gene            complement(13343..13768)
                     /locus_tag="VQU19_001359"
     CDS             complement(13343..13768)
                     /locus_tag="VQU19_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HET2480602.1"
                     /translation="MIEIQDLLYQLRLSEQASTQLFEKRLGISLTRYQILLFLLEHSP
                     CNQMAVQERLKIDQAALTRHFKILETEGLVERHRNPENQREVLVEAAKYAKEQLVVNP
                     PLQHIKVKEEMESILTEFERTELSRLLNKLVLGIENIEI"
     gene            complement(14193..15335)
                     /locus_tag="VQU19_001360"
     CDS             complement(14193..15335)
                     /locus_tag="VQU19_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HET2480603.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASSSEVTKTV
                     IASEEVAPSTGTSVPEEQTAETSSAVAEEAPQGTTPAEKQETQASPQAASAVEATTTS
                     SEAKEVASSNGATAAVSTYQPEETKIISTTYEAPAAPDYAGLAVAKSENAGLQPQTAA
                     FKEEIANLFGITSFSGYRPGDSGDHGKGLAIDFMVPERSELGDKIAEYAIQNMASRGI
                     SYIIWKQRFYAPFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            complement(15501..16121)
                     /locus_tag="VQU19_001361"
     CDS             complement(15501..16121)
                     /locus_tag="VQU19_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET2480604.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQNLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNTFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            complement(16125..17405)
                     /locus_tag="VQU19_001362"
     CDS             complement(16125..17405)
                     /locus_tag="VQU19_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HET2480605.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTILSRLVGLVILWSQLKLPYGKLTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            complement(17466..18950)
                     /locus_tag="VQU19_001363"
     CDS             complement(17466..18950)
                     /locus_tag="VQU19_001363"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HET2480606.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLDF
                     DKLKDASYQEVAKLVLSAFLDDFTAEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKGGVSKVQELQMTTQNGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGEKVNFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTAELMNALNTQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVYESDS
                     YIEDPHTAVASAVYRKYQAVTGDVTKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLEIAPIRHKTTVAAADMQAAVEAYLGL"
     gene            complement(19026..20303)
                     /locus_tag="VQU19_001364"
     CDS             complement(19026..20303)
                     /locus_tag="VQU19_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HET2480607.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATSEIQAFALNGDEVIIYPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            complement(20410..20493)
                     /locus_tag="VQU19_001365"
     tRNA            complement(20410..20493)
                     /locus_tag="VQU19_001365"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20457..20459),aa:Leu,seq:caa)
     gene            complement(20503..20574)
                     /locus_tag="VQU19_001366"
     tRNA            complement(20503..20574)
                     /locus_tag="VQU19_001366"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20540..20542),aa:Gln,seq:ttg)
     gene            complement(20588..20660)
                     /locus_tag="VQU19_001367"
     tRNA            complement(20588..20660)
                     /locus_tag="VQU19_001367"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20625..20627),aa:His,seq:gtg)
     gene            complement(20675..20745)
                     /locus_tag="VQU19_001368"
     tRNA            complement(20675..20745)
                     /locus_tag="VQU19_001368"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20711..20713),aa:Trp,seq:cca)
BASE COUNT         6229 a         4727 c         3668 g         6191 t
ORIGIN      
        1 tggtattatc aatcatgaac taggattcta gttttgcagg aagtctaata atgaaaataa
       61 aggactaaag caataactct aaatacatct gatttttata ggatatttca taaaaaaaat
      121 ctacatacct agagtcctat ttagttatgt atcttacata aagagaaagg aattaattat
      181 catgaaatta tctttgtata gtgaagttga acattaccat tttttaagtt cttattcttt
      241 aaatgatatt acatatactg ataccccaaa aaatattatt gaaaagtcta aaaaagataa
      301 gtatagatac ccaatagtaa tacttaataa agaccataaa gtaattggat ttttttgcct
      361 acacctaaac actggtccta aagagtatgg ctattatcaa aatgattatg cgcttattag
      421 aggattttct attcatgata atttcagaaa tcaaggatat ggttctaatg ctctgaatga
      481 aatatttgaa ttcatagact caactttaaa attagaaatt aaccatatta tattggctgt
      541 aaatgaaaaa aatatattgg ctcaaaaagc atatagaaat tccggttttt ctgttgtgaa
      601 aaaagattta gaaggaaaaa gggggaaatt aattattatg gagaaaagca gaaactagta
      661 atgatactag tttctgcttt tctctaagtc tgctataaat ttataacatg ttgaaataag
      721 atgtgaataa attgattgca gaattcaaac caatttctaa caatgtttta gaaaactcgg
      781 cggactattc cagattcaat ccactatatt ctatcttatt tgcatatttt gagagaaata
      841 atctatatac taaactttta tgtttataat tcattccttt cgtttcactc aaggcacaag
      901 acagaatgaa aaagtggtgt gctctttatt ttgttttata ataatagtga gaaaacctat
      961 cactactaca aatcacgggg aggtgaataa gtgagtggta tagccactac ctcgcatttt
     1021 tataggtgtc attctttcca tcaagcacaa gaactgtgac taggagcacg taaacttata
     1081 attgaataag cgactcgttt gtgaaaggaa agaatagtca agggataggc agactcaaat
     1141 ttggtgaagg gaaacccctc atgttaaaag ccaaacttca attttaaaaa ttttaaaatt
     1201 tgtttcgtat tcactactcc ttgcctttat attggattga ttaagagaac ctttcgcgtt
     1261 tctagaaact acagtggact attctggatt caacgcatta tagttgaatt gactaggaat
     1321 tctctttctt ttcaggcttc tcttctgatt tttttctccg ctttttcgct tgaatcagtc
     1381 gctacctctt cctttttatc cgttttctct tctttgattt tgactgaagg aaacagaaac
     1441 tcatattgac tcttatccgt acgaacagtc gtcaccaagc ttgttttctt gttttgatag
     1501 ctcacctgac ctagattaaa aacctgttcc ccactttctt gctcggcttt atccttggtt
     1561 cgtttagcca tggcaaaagc aaccaatttt tctttattta aagcatagtc ttgatagtgg
     1621 gcgatttgtc gggtcaaata aaattgcaac aaaagactaa agatggctgc tatggtgact
     1681 gcgtagagga gaacacctgc cttaactttc ttctttttcc acacgataga tgaactccct
     1741 ttctaagcct ttttgaaact ggaaacgaaa atgaaccagt tgattgtcct ctgtaatctg
     1801 agctgatttg aggccataaa ccataggctg atacccccgt ccactagcat cggttttacg
     1861 aaaatcgtct gactttgact taccgatggc gatgtccttg tcatcttgct tcatgtatag
     1921 gcgattgcct tctacttttt cgaactgcga acggtctaat tctgcctcaa gttggcccac
     1981 aaacaagagc cactcctttt gctcgctttg ttgctggtag cgaacttctg aaatgaggag
     2041 ctgactcata gcttgaaaaa ggagtaatcc cccactgatg acaatgaggg caagcaggga
     2101 ttctaacaag gtaaaagcct tgaccttatg gctctttgat tgccaacaac tgttctgaac
     2161 catggtagac ctccaatccc ttttcactag aaaatacctg aatctcaact ccgttgatgc
     2221 ttacctgatt ttgccccgtc tgcaaggcca tcttagctac cctcaagact tcttcctttt
     2281 gcaagatttt tgcttcctct tgcctatttt tttgaatttg tcccaaaagg agggtcgcaa
     2341 tgctggcaaa gatagctaga gcgactactg cttccagtaa aatcactgcc ctaatttttt
     2401 gtttccttaa tgcgtttaat ttttccattt cctagatata attgatagcg aatcgctcct
     2461 ttactggtct gaaattcaac cttagccagg gacgaattgc ccccagctcg gtcaaatgta
     2521 atactttggc ctgatggtgc ctgaattcct ttaggaactg tcaacttttg actgccattg
     2581 ctaatcatct gcccatccaa gttcagacta gtcttttgtt gactagctac actgcgtttt
     2641 tgggtttccc gatagagttc ttcaaactcc ataaagaaaa tctgttcctc taccgctgca
     2701 aaagtggact ggacagagcc ggacaagccc aaggcaagga tactcacaag tcccaaaacc
     2761 aagagacttt ccagcatggt aaaggcctta atcattgact ttacgatttg cccctccatt
     2821 tttagtatag tattcattat aagctttaac ctgttcttcc gtgatgcgcc catctccttg
     2881 taacttgctc agagtagcat cttcattttt atccaagcta taaagttctg cctggctttc
     2941 caccacctta acaacagctg cttttccttt gtcattgact gcttcttttt gcttggtcag
     3001 attaggtaca aagagcaaga aaagcacgct gataatcagc aagaccacca acatctccac
     3061 caatgtaaaa gctttaacct tagctttttt caagaatgtc atcatttttt tcattttaaa
     3121 aatttacctc catattttga tacatgggca tgagcattgc cgcataaagt aaaacgataa
     3181 tcagtgccac aaagataaaa accagtggct gcaccaaatt catggtgcgg ttgactcggg
     3241 taaaaaaggc ttcccaagtt ttttcagcat agatttccaa ctcactaccc agcttggact
     3301 taacttcccc atactctatg atgagactca attccttcct aaagaaagga taggttccta
     3361 tcgtctgaga aaattcacgg ccatttttca gggtttgagc cagatcttga ccgatttctt
     3421 taaagagctg ggaaccttgt tcctgcatca tttgaaaaat ctgcgtcagc tccattccct
     3481 gtgaaatcat attcccccat tcacgtgcat aataggctgt caagtaggtc tgcacaaaga
     3541 ttccaataaa gggaaggcgt gctaagatag aaaagacact catcttagaa cttcttttat
     3601 aaaaagttag tgctaaaagg gcaagcacgg aaacaagccc taccatgcct agaaaaattt
     3661 gtggcagatt accgataatt cgggtggcaa tattgctact atccagttgt gggagcaggt
     3721 aattccgtag ccccagcata attaagagaa gaaaatccag caaaatcaaa ggataggtcg
     3781 ctacttcaat taactttttc ttgaccttgg ccagattgtc tagatattct tctatctttc
     3841 ccaaactcag gtgaagattg ccatgaactt cagctagaga taactgagtg acaatggtac
     3901 ttgaacatcc caaactttcc atcatttctg agaatgattt cccctgagac aagcctgtac
     3961 gcatctgggt cacacactgc ttgtccaaca aggaactcct atctaaaaag gagatagtct
     4021 ccaccagatg aaaaccgcta gaaaagagat tgttaaatag ggtgatgata tttttttgct
     4081 tagctgtagc taattttttc cgtctcagcc tgaagacttg tgatatgtcc atctttaaga
     4141 agttggtcaa tttgctcatt ccacttggct gcttggtgtt cttgataatc tctgtttgca
     4201 aagtcaacga ttcctcctcc cccgattaat ctctggtagc agactccttg cagaacaact
     4261 gccaattctt cttcactcac acccaactcc agcagacgct cataaacacc tcggatactc
     4321 ttggcgtgaa tggttgaaaa gactgtcgca cctgtcaaac tagctctgac cactgcacgc
     4381 gccgtctcgc tgtcacgaat ttctccgata atcaagagat ctggtcgatg acgcaaggaa
     4441 agtttgatta gattttcata ggttaggccg attgcttcgt tcaactgcaa ctgaagcatg
     4501 tcgtcctgct tgatttcgac aggatcttcg atggacataa cttgctgtcc tttaaagagt
     4561 gacttggaca attcatgcat caaggtcgtc ttaccactcc caaccgggcc agcaaaaaga
     4621 tagagtcccc gttgcctgta ctgcttgcct aattcttcaa tatcctgaaa ccaaaaatgc
     4681 aagtcctgct cctcatcgtg caacaaacgg ataaccaaac tctcatgccc ccgataatcg
     4741 cctacagtag ataaacgtag agacgccatc ttctggtcat aggcataatc acaggaaccc
     4801 agttgactac gtcttttttc tcccacattc atacccgcca caaacttaaa gtgactgata
     4861 acggctgcaa acttttcaaa atcatagcta ccaattttac agcgctcgtc tcctaccctc
     4921 atatgaagct cataggcgtc taacttaggg acaaaataaa tatcctgcgt cccttttttc
     4981 cgagctgaac gaatgatttc ttgtgcaatt tcttgaacca tacttacctc ctcacctata
     5041 ctattcgcaa agcgttagaa aaataaaaaa agcaactcca aaaaagttac ttttctctat
     5101 tttaatttca tacggcaaga acgattcctt tcctgactgg tttgtttttc atagcctgag
     5161 cgtagttttt cgtctgggat aacctgctca tcctgcaaaa gagccaaaga atggtattgt
     5221 tgtaaatact catcacattc atcacaccag cgttggtctt ccgggtccca aaaaatggtc
     5281 atcaagtcgc ttctactttt ataaagaggg gattcttgtt ccaatctaaa ccagcaagtt
     5341 ttgtagtatt tgagagcatc ataatactgg tcaaattttc tacttgctac aatatcttct
     5401 tcccaacctt ctaagaacca ccacggttca aaatctccgt acatttctat aacacgatac
     5461 atattcattc attcctttgt accgtatatt ataaccaatt ccgccagaca aggaaagaaa
     5521 tatgctcatt tcttaatttt ttgataaaaa atccagccat ctgatggatg actgaatttc
     5581 tatttgctta tgtacaaaaa tatttttact acttaggctt ctgagatatc gttttcgata
     5641 atgaccttaa tggcatggtg gtctgctgcc ttactgaaga cttcgtaggc tttttcaatt
     5701 tcactgagtt tgaaatagtg agttaccaat ttttccggtt caatcttatg actttcaagt
     5761 gctttcaaca attgtggagt cgtatttgta gataccaaac cagttgttac attgatgttg
     5821 cgaatccaaa gtttatctaa atcgaattca actggtttac catgcacacc acagttggca
     5881 accgttccgt ctacaccgat aatcttttga cagaaatcaa atgtttcagg aatccctaca
     5941 gcttcgatag cgacatccac accacgacca tctgtcaaat cataaatttc tttaatggct
     6001 tttttagggt ctgaagaatt aaccttatga gtcgcaccga atgatagggc agtttccaag
     6061 cggttatcgt ctaggtctac cataatcaat ttagctggtg aatagaattg ggctgttaaa
     6121 agagcagcca atccaactgg acctgaacca ataatggcta cgctgcaacc aggttctact
     6181 ttccctttta agacaccaat ttcatatcca gtaggcagaa tgtctgacag cataaccaaa
     6241 gcttcatctg acaagtcttc tggagtatgg taaagagtat tatctgcatg agggacacgt
     6301 agatattcag cctgcatacc atcaatcaag tgaccgaaaa tccagccccc ttcgtcttca
     6361 cagtgggcat aaattccttt tttacagtag tagcatttac cacaggcaca gacgcaagaa
     6421 atcaagacct tgtcaccttt tttgaagttg gaaactcctt ccccaacttc ttcaacaatc
     6481 ccaatccctt cgtggccaag aatggtacca ctttggcaag taggaacatc ccctttgata
     6541 atatggaggt ctgttccaca aatagtggtt tttacaatac gcacaatagc gtctgttggc
     6601 ttgcgaataa ctggtttgtc tacatcaaca aaagaagcaa gtcctggttt aacataagta
     6661 taggctttca taaagcactc ctccgttttt ttatttgtaa tatttatagt tcaattgtaa
     6721 gcctttttct ttgtttcttc aagctttttt tgtgattttt ttaacttttt atttaccagt
     6781 aaagtaccct gtataaaaaa gcagaagcta gtctctaact tctgccttct ctcttatgct
     6841 tgataacgtt tcacaccatc taggtaggtt gctaccaatt ccaaatcttt atctaatacg
     6901 atgaagtcag cgtcgtagcc ttcacggatt tggccacaga cgtcatcgat gtgaacggat
     6961 ttagctgggt tgaagctggc catcatgact gcttcatgcg gattcgcaat tccccattcg
     7021 accacattct tcaaaccatc tttgagtttg aggatagaac ctgccaagtt acctgtcgat
     7081 ttgaggcgtg cagttccatt tgcaacgaca actgggaatt ctcccaacat ataatctccg
     7141 tcttccaatc ccccagctgt catacagtct gtgataagag cgatgttttc tgttcctttt
     7201 tgtttgataa gaatttcgca agcctttgga tctacgtggt gaccatcaca gatcaactct
     7261 gcataggtat gtggcaattg gtacatggct ccaaccatac ccaattcacg gtgagtcaac
     7321 ccacgcattc cattgtaggc atgcacccaa acactcgctc cagcatcgac tgcttttttg
     7381 gcttcatcaa aagtcgcgtt tgaatgtcca agagcaaccg tcacaccttc gcccgtaact
     7441 gtacgaacaa agtcttccac cccatcacgt tctggtgcaa gggcaatttt attaagcaag
     7501 ccatttgccg ctttttgcca agaatgaaac tcctcaacac ccgggtctct catataagtt
     7561 ggattttgtg cccccttaaa agtttctgtg aaatatggac cttcataata aatcccacga
     7621 atcttagcac ctgttgcttc tttataatgg tttccaagat tttcagtgac tgcaagcaat
     7681 tgctcataag tggctgttaa agttgtgggt aagaaactgg taacaccggt actaagaagt
     7741 ccttcactca tagtatgcaa tgtaccttca atgttgttgt ccatcacatc tacacctgca
     7801 tatccatgaa tatgagtatc cacaagtcct ggggcaatgc tataacctgt atagtcaatc
     7861 acctcagccc cttcaggaat ctgctctaca tgtttcccaa acttgccgtc cacaagttcc
     7921 aagtaaccac ctcgacgaac tccgtgtggg tagaaaaact gatccgcttt aatatagtta
     7981 ggcataatgt taacctcctt aaaagattga ttctacaatt tattatgtca attacattat
     8041 aaacctttct tttttatttg taaatggtat agacctattt tttggagata ttttaaaaga
     8101 gctggatttc tccaactctt ctctttttta atacaagtta ttttgattta accggcttgt
     8161 cttgagctgt ctgcaaagct gtggcaatcg tatctgcata caattttgct cctgcttcga
     8221 tagtgctact ctcactcccg aaatgaacct ggtctgttcc agcccaaatt tctggatgct
     8281 ctttcgcaac ttgattccaa tctgctatcg taatgtaagg tgtcttctct gccaattctc
     8341 tcatataggc agcagccttc tcaacgatgg cataggtctc ttttgtctta tctccctcat
     8401 aaggagtcac caaaatcata tggtgtccct taggaagatt tttcacgata ctgtcccagt
     8461 catccttgta attctcagga ttatttaccc cagtcgcaat gaccaccgtc ttaggtaaaa
     8521 atttattctg gctattattt agcatgattt catttgcggt cttggttgtt acgctgacct
     8581 gcgcgttaat ctgtgctcca ggaagagctg tctgtagtgc tgtatttgcc cttaaagcca
     8641 ctgagtcacc aattaacata gtgccatcag caattcccaa actgtttgca tctgcccgtt
     8701 ctgccatcac cttggtctgg ccaatatttg ttgcagcttg cttcaagcca ttgacagtca
     8761 agtctgtctc aaacgctccc acttgtggtg ccaacaaggt caccatgcag acaatgaagg
     8821 tcaagattcc tgtacctgct gcaagaattg cgtgaatata aggcagggga cgaagagttt
     8881 gtaaaatagg tgtgttcttg cctgcaatcc aaggttccaa tacataaaat gacagactgg
     8941 caaagccata agaacaaatc agagtcagta atacagcaag aagatttgat gtcaactgtg
     9001 agaaaatgat atagaaaggc caatggaaaa gataaaccgc atagctagta tccgctaaaa
     9061 agctgataat cttcggctcc tgtatatgat gtgtcttttc atgtaagaca cgcgccgcca
     9121 gaatcatggc aagagctgca agactggcaa gcaagaagcc gataagatag gcaaaaagat
     9181 aagtgaattt gacaaagaaa gtcaaaagaa ctaggaaacc aaagcctcct ccaaaaacta
     9241 ctaaagtctt tcgtaaatcc cagattttat ccaactgctt gacgagggaa gtcgtctgac
     9301 gaacgcctac aatagttgct aacatacttc ccaaaaagaa tggatagaca tgagttaaac
     9361 tggagaaata aacagaggaa taagaggtca ctagaaaact accaataaac atggagaaga
     9421 aactgatcaa gaaggcagta gcagataaga gaaagatcat ccccttcaac tgaccatttg
     9481 atttagcttg tttggataag aaccaaactg ccaatcccca aagaatatag tagtgaacct
     9541 caactgccaa actccaatta tgaacaaaca aatgaggaat gaactgagat tcataactcc
     9601 cacctgttaa gagttcatag aagttggtca taaagcctaa gacgcccgca atctggccac
     9661 caattccagc aacatagtct tggcgaacca agaaagtaaa aggcatggtc accaagacca
     9721 tcaaaaccac aggtggcaca atccgataaa agcgtcttct aaaaaatcct atcaaatcaa
     9781 tctcattgtt cttagaaaat tcttcaatga gtagagctgt aatcaggaaa cctgaaaatg
     9841 tgaaaaagac atctaccccg aaaaatcctc caggaaagat cgtctgaaag aagtgataca
     9901 agagtaccaa aagtaaacct ataatcctaa tcaaggaaaa ccatttaatg cgcatacgag
     9961 tttattcttc ctttcattgt acactttatt ctatcaaaaa aagaagaaaa atcctaagag
    10021 aaaacttagg atttttagct tatatcaatt ccattttaga aattacgtcc tgacttatta
    10081 tagccatatt tttccacaaa atacttacgg aattccaaga gattgtcatc catgatggct
    10141 tgtcgcactt gcttcatcag gttaagcaag aagtaaagat tgtggtagct agtcaagcgg
    10201 ataccaaagg tttcatcagc cttgagcagg tgacgaaggt aagcgcgtgt atagttatta
    10261 catgtgtagc aatcacactc aggatccagt ggcgtaaagt cctcagcaaa ctgggcattt
    10321 ttcacaacca aacgtccttg actggtcata caagtcccgt tacgagcaat tcgagtcggt
    10381 aagacacagt caaacatatc caccccacga atgaccccat cgatcaagct atctggcgct
    10441 cccacaccca tcagataacg aggtttattt tcaggcagca gttgagttgt aaagtccaag
    10501 accgcattca tctcttcatg ggtttctccc actgccaaac caccgataga gtagcctgag
    10561 aaatccatgc tgacaagatc gtgagctgat tggcggcgaa ggtcttcaaa tcctgcacct
    10621 tgcacaattc caaacaaacc ttggtcatgt ggacgacggt gagccttcaa accacactca
    10681 gcccaacggc tggtacgctc gatcgatttc ttaacgtagt cataaggttg ataaaactga
    10741 ggacattcat caaaggacat catgatgtct gaacccagat tattctgaat agagatggct
    10801 ttttctgggg ataggagcat cttagaacca tttagatgat ttttaaaggt tactccttct
    10861 tctgtgatat tacggctatc tgctaaagaa taaacctgaa aaccaccact atctgtcaag
    10921 ataggctggt cccaattcat gaacttgtgg agaccaccag cgcgtgcaat gagttcatct
    10981 ccagggcgaa gccagagatg ataggtgttt gataggataa ttcccgaacc catctccttc
    11041 aattcttcag gtgactgagt tttgacagtg gcttgtgtcc caactggcat aaacataggt
    11101 gtcggaaagg taccgtgggg agtgatgatt tctcctagac gagctcctgt gtgtttttct
    11161 ttcttaatca aacgatattt gattggtgaa tctgacattt tttacctccg aagctgggaa
    11221 agacagtccc agttcataca gtgtgcccaa ggacacactg tatgatttta tcaaaaaaag
    11281 taggaactgt cacgaactat gtataagaac tatggtataa taagagaatg aactatccaa
    11341 aaattgattt aaaaacaatt cgtcaggagt caaaacattt tcaggctgac accccccgtc
    11401 tctttctcct ctatatcctt cccagtatgc tggtcatctt atctggtttt cttaatccct
    11461 tatctcggat ccacgggact gttttagaac agccattttt cagcatactt ggccaaatac
    11521 ttcaaaccta cctctttcct ctactagtct cctttatcgg gactattctt ttgaccagtt
    11581 ccgtctatgc aacactgaca ctcatgaaag attctaaaac ggagccatct gtaaaaaaca
    11641 gcctagctct ctttgatgag gagcgctttt ctcaaacctt tttgacccta cttctcaaac
    11701 gtttctatct ctttttatgg agtatcccta atttacttgg gatttacctc ctcttttata
    11761 gtagcttttt agccaaaaaa ttcgtcaccc tacatcctga gtttccaaat ctagatctct
    11821 catcagttga aaccgagcgt ttcctcatgg tctttggact ctactttctt gcaagtctca
    11881 tcttgatcat tgtaggaaat atcctctata ttccacagta ttatgcctat tcacaggtgg
    11941 aatttcttct ctgttatagt ctagacctag gacaggtccc accaagacga atcctaaaaa
    12001 ctagccgttc ctttatgaag ggctacaagt tccagcactt tgtcctagat ttacagcttc
    12061 ttccttggta cttcctcaat tggattacct ttggcattgc tagtttttca ctcctacctt
    12121 atatccaatg cactaaaatt atgttttacc gagcagtatt ggctcgaaaa cgtccaaaag
    12181 cttgaaggtt tttcccctca agcttttttc tatcaatgag tttctccgcc taccaacttg
    12241 agttcctgat ctccatgttc tatcatagcg ccgattgctg cttctatccc tcgccgaata
    12301 tccactaaac tcatagttgg agtagtcggt ctgttcacca cctgttccat catataagga
    12361 atatgcataa aacctgcctt aacatatgga aatttctttt ctaccaaata gagagcctga
    12421 tacatcaaat ggctgcagac aaaagtccct gccgtattgg aaacagaggc cggtaagccc
    12481 tcttttttta tagcttgaac catcgcttta atcggcaaac tactaaagta ggccgaagca
    12541 ccatctgggc gaatgggacg gtcaatcggt tgattatctt cgttatcaga aatgcgtgca
    12601 tcgtcttgat taatggccac tcgttcaggt gtcacactag ttcttccacc agcttgccca
    12661 atacaaagga caaagtcagg ttgataacga ttcatctctt cttccaatac ttgagcagat
    12721 ttgtgaaaaa ctgtcggcac ctctagccaa cggacctcag caccatggat ttcagctggt
    12781 aaacctttaa tggcctccaa agttggattg cccttttccc ctccaaaggg ctcaaaacct
    12841 gtcactaata ctttcatttc taactcctca aaaccaattc aatgagactt ttttcttaaa
    12901 aacaagtata acatatttcc cttattctgg attaaaaagg attagcgaga ttaaaatcga
    12961 ccttcaagtg tatttaaaga gtaaaatact aatcaaggcc aaaatagctg atccaccttg
    13021 cttcaaaata atttttttat ccgctgttaa agagccgtaa gtcgcagcac caatcacaaa
    13081 taagacaaaa atagtcacaa tttctaaatt ctgtgagaaa taaatgccat accagagaaa
    13141 gactcctagc agagccttat aaatcccttg atttttgaac aatgaactta ctgacggatg
    13201 agccaattct tccttttcca tattaaatac acgactagtc gcatctgatc gcgtagcaat
    13261 actttccaaa taaaaaatgt aaaaatgctc caaagcaacg atcgttgtta aaataattgt
    13321 aataattgac atctatttct ccttaaattt ctatattttc aatacccaaa accaatttat
    13381 ttaataaacg gctgagttct gttctctcaa actctgttaa gatactttcc atctcttcct
    13441 taaccttgat atgttgcaga gggggattca ccactaactg ctccttggca tacttcgcag
    13501 cctctaccaa cacttcccgc tgattttcag gattacgatg acgctccacc aaaccttccg
    13561 tttccaaaat cttgaaatgc cgtgtcaaag cagcctgatc aattttcaaa cgctcctgaa
    13621 ccgccatttg gttacaagga gaatgctcca gcaaaaacag taaaatctga taccgtgtca
    13681 aactaatccc aagccttttt tcaaacaatt gcgtactcgc ttgctcagac aagcggagtt
    13741 gatacagtaa atcttgaatc tctatcattt cttcctccta tccattgact tatcaatagt
    13801 tgaccaatca attataatat aaagtatagt gaaatgaaat aagagcagga caaatcgatc
    13861 aggacagtca aatcgatttc taacaatgtt ttagaagcag ttgtgtacta ttctagtttc
    13921 aatctactat aaaatagatt gcaagaatgt tgcttagatt attacaagat gataactttc
    13981 cattttccat tcaaattgat actcaatgaa aatcaaaaag caaactagga agctagtcgc
    14041 aggttgctca aagcacagct ttgaggtttc agataaaact gacgtggttt gaagagattt
    14101 tcgaagagta tgacaaagaa aaaacgaacg agaatcgctt cccatcacga aagctagatc
    14161 tcattcgtca aaatgatgtt accaagtcgg gtttatccat tcattgaaac gtgaacgtga
    14221 tcatagtgat tttctgtcac actaccacgg tctggcattg ggttccaagt gttagctggc
    14281 ccatatttgc tatcgaatgg agcatagaaa cgttgtttcc agatgatgta actaatgcca
    14341 cggctggcca tgttttgaat agcatattcc gcaatcttat cccctaattc tgaacgttct
    14401 ggtaccataa agtcgatagc caaacctttt ccgtgatctc cactgtctcc tggacgataa
    14461 ccgctaaagg atgtaatgcc aaacaagtta gcaatttctt ctttaaaggc agctgtttgt
    14521 ggttgaagac ctgcattttc agattttgct actgcaagtc cagcataatc gggcgcagct
    14581 ggagcctcgt aagttgttga aattattttc gtctcttctg gttgataagt agaaactgct
    14641 gctgtagctc catttgatga tgctacttct tttgcttctg aacttgttgt agttgcttcc
    14701 actgctgatg cagcttgagg gcttgcttgt gtttcctgct tctcagctgg agtcgttccc
    14761 tgaggagctt cttctgcaac tgcactgctt gtttcggccg tttgctcctc tgggacagaa
    14821 gtgcccgtag atggtgccac ttcttcagaa gcaatcactg tctttgtaac ttctgaactt
    14881 gatgctactt cttttggagc ttctgcaatt ggttgagaaa ggtctgcaac ctgaacagtt
    14941 tgatcatcaa cggtcacttg attagtggtc aaatctgctg tcgcagttgt cacttcttca
    15001 ctagagtctg cttgaggtgt ttggatttca acttctgtta cttcttctgc ttcattgaca
    15061 gtcgttgtca aaacagtttc tgggaaaatc aagtccatat tagtgatttt gttcagattc
    15121 gcaagcactg tgacatctac acccaaggct tctgcaatgg tgctcaaagt atcaccatac
    15181 tgtacggtat aacttgtttt gttgtccgtt ttagtcaaat cgttttggat ttgctcaaca
    15241 ctacgtgcag tccaaagaac ttcttctgct tgagttgcca atactggggc aaatgacaag
    15301 gctactgttg acgctaataa cattcttttc ttcattcttt caaattcctt tcaaatgagt
    15361 acctgtctat cataacacaa aaaatgtaga aaaaaagccc tctcgggcct atttaacaga
    15421 actgtctatt ccttgtaaca aactagatta cttgaaatag tttgttaggt ctctgtcaca
    15481 aaactgacac aatcttttta tcacttagtc tcaaaaatac gggaaatatc tgctaacgct
    15541 tgaatcctgt gattcccttc ataagtagac tctaaaaagt tgatactttg aatcccacta
    15601 ttctgggcaa attccacatc cagagtccga tcccctatat aataagtatt atcagaattc
    15661 aactgatact tatctagcag ataggtagcc gcttctggac ttggcttccg cacaaagcca
    15721 ctctgactgg tcaaaatctc tgtaaaatag gattccaccc ccaagtcctt gagaatggta
    15781 aaagtgttgt tccccttatg agtatatata aactgctgaa ttcctgattc gtctgcccaa
    15841 gctagcacct cacgcgcacc tggcatcaaa actacctgag cattcttctc agccagactc
    15901 tgggcacgca cctgatttag cacctcaaca tccagatttc tatcttctgc cacccgcaca
    15961 agcaaatttt gcaccgaata cttgaagata aactctctca ccttctcctt atcataagga
    16021 atagaaaact gagcaaaagt ctcctcaatc cctgataaaa tcgcttcgta agagtccaat
    16081 aaagtcccgt ctaaatccca aataaaagct gttttttgca tttcctatcc tttcaagctc
    16141 atatagcgct ggtaacgata gcgtagaaat aaccagcgaa aaccattatc caagagagac
    16201 cctgcccaaa taccaggcaa gccccaacca agcacaatac ccatcagata tcctgtccca
    16261 atgcggatac accacatgcc tatacttgtc gcataaaaag ggaggcgtgc atttcctaat
    16321 ccctgccaga ctgccgtata gatgactgtt cctgtcgtca taggggtacc aagtagtgaa
    16381 aacagtgtca ctagaacact agcctccacc gctagagaat cagtcgtata gagatgagtt
    16441 aatggtacac ccaagacata tatactaaag gacaggggca acatgaggaa cagagaaagc
    16501 caaaaggttt gtttactcaa actagcaact cttttccaat catcctctcc aactgctcgg
    16561 gccaacagca tgaccgttgc cgtagcgaca ccaaaggcag gcatatagtt aaactgggtc
    16621 aagacttctc cgattgcatt cccagcaact gcctccgtcc caaaagaaac gaccaaggca
    16681 atgatcacta catctccagc cctcatcata agtcgctctc cagctgctgg taaagccaag
    16741 gtcaacagtt ccttatctaa accaaaagtt agcttcccat aaggcagttt taattgtgac
    16801 cacaaaatca caagaccaac caaacgagac agaattgtcc cccaagcaac accagctatc
    16861 cccatatcca gaacaaaaat agctagactt gaaaaaagaa tattcaaggc attggataaa
    16921 aaactaacat agagaggcag acgtggatta tgcgttgcac gaatcaaggc tcccaaacta
    16981 gtcattaaac ctaagagaac aatcgatccg cctaccaaag atagatacag tccaccactc
    17041 tcagctacat ccctctccgt ccccaaaagt cctatcatct ctttcccagc gaagatggac
    17101 aaaaatccta aaaggaaact taatagtaag gtaatcttca acgcctcagt cacatgatag
    17161 gccaacttcg actggtcttt ctgccctatg ctttttgaaa taacactgga aatagcagct
    17221 cccagagcga tgaaaatcgc ctgataaatg gtgataatat taccagctac tgaaacccct
    17281 gaaatagcta tcaatcctaa atgagcaacc aaataactgt ccaccattcc cattagcatc
    17341 tgcaaaaagt tttcacccat agctggcaat gcaatattaa gaatgtcttt atttttctta
    17401 aacaatctct cctcctgatg aaaagaaact cagttggttt cccaaccgag tttgctccct
    17461 ctgtcttaaa gtcctaaata agcctcaacc gctgcttgca tgtcagcagc tgccactgtt
    17521 gtcttgtgac gaattggagc tatttcaagc ccatcaactg ctggtggcac tgcaacgcct
    17581 gagatttcat gtaattgagc caaggcttca aagtctgtca aacctgcttt tccagttaca
    17641 gcttctactg caactactgg gaacttgtat ggactagctg ttgaagcaat cactgtctta
    17701 gttacatctc cagtaaccgc ttggtatttt ctataaactg ctgaggcaac cgccgtatgt
    17761 ggatcctcaa tataagaatc tgactcataa acacgcttga tttctgccgc tgtttcttcc
    17821 tcagtcgcat attcagctgc aaagaggtcc aaaatctctg catcaaagtc tgtcaactta
    17881 tattgtcctt gcgtgttcaa ggcattcata agttcagctg tcttttcagc attatttccc
    17941 aaaagatgga aaatcaagcg ctccaagttt gaagatacca agatatccat agatgggctg
    18001 gttgttacct taaactcacg ttttttgtca tagacacgtg ttttaaagaa gtctgtcaag
    18061 acattattgt catttgaagc acagattagc ttgccaactg gtaggccgat ttgtttggca
    18121 taaaaggcag ccaagatatt tccaaagttt cctgttggta ctgtgaagtt aaccttttca
    18181 ccagctacaa tttcaccagt cttaaccaat tgagcgtaag cataaacata ataaacaatt
    18241 tgtggcacca gacgaccaat gttcatagag ttagctgatg aaaattgcaa cttgttggta
    18301 gtcaattttt cacgaagagc cacgtcgtta aacatgtgct tcacatttgt ttgcgcatcg
    18361 tcaaaattac catcaatagc aataacatga gtattgtcac cattctgagt ggtcatttgc
    18421 aactcttgta ccttgctgac accacccttt ggataaaaga cgataatctc agtaccaggc
    18481 acatccgcaa accccgccat agcagctttc cccgtgtcac cagatgtcgc tgtcaagata
    18541 acaatcttgt tctccaaacc atgtttctta gcagcagtcg tcataaagta tggcaaaata
    18601 gacaaggcca tatccttaaa ggcaatcgtt gaaccatgga aaagttccaa attgtattgc
    18661 ccatctaatt tcactaatgg tgcaatagct ggagtatcaa atttgctatc gtaggcattg
    18721 ttgatacagt agtccaactc ctcagctgta aagtcatcta aaaatgctga caaaactagc
    18781 ttagcaactt cctggtaaga agcatctttc aatttgtcaa agtccaaatc tacctttgga
    18841 taagtaaccg gtgtaaacaa accgccgtcc gtcgccaaac cttgcaaaat tgcttggctg
    18901 gcagttactg tattgttggc atcacgcgtt gattgataaa ctaatgtcat tactctctat
    18961 cctttatcta tagtctcgtc cattatatca tgatttttca gaaaattctc cctttataag
    19021 agaaattata ggctcaattc ttctctcaaa ggctgtaaat aggtcatttc ttccttattt
    19081 ctcaccacta gtccctcctc agctagtagg agtaagtctt tggaaaattc aataatcgta
    19141 gtttcttcct catctgtaag atttttctta gaaaattgtc tccttaaaga cttgtaatca
    19201 taaccaaata ctttaaagaa aggtgctgtt tctaagtaag cttctaactt gtctaaatta
    19261 accaataatc ccaagtgaaa agctgcagaa gcaaaagtcc tatcaagtgg ctgtgtacac
    19321 acactacgaa actcaactgt tcctcgagtc gttaaatctt ggtactggta actacgatga
    19381 gtttcaaaat ccttctcttg ggggtaaata ataacctcat ccccattcag agcaaatgct
    19441 tggatttcgg acgtagccaa atagtcccca gcctgaatag gataaaaata ataggtctgc
    19501 ccatcacgtt ccgcagtaaa aatcgcagaa tgatttagat agtcaaaaaa atcagcttca
    19561 tcattaagga gtctagcatt gaccccaaca ttctctggat agataccatg catagattct
    19621 tcccagaaaa tatcccttga aattttcgta tcccaatccg cacccgaaaa ttcagagttt
    19681 gcaaataaat aagccttagc cgcttcaatt tgagtaaaag cattaatcac ccgtaagtag
    19741 ttggtttttg aaatatccag ctgaacctgg ctcccacaga taaaagtacc atattcaggg
    19801 aaatgatgta aatctgattt aataatattt ctactcaaat tcaaataatc catcaacatc
    19861 tgatagcgtg gataagccac tggacaattc tcatttttat cccagttggg atggatacca
    19921 cagccaacaa tagcatgatt tgattcagct aactttctct gaattacatt catataatta
    19981 ttgaaacgat tttcgacctc ttgaatcgtt tcagccttac caaatgcaaa ctcaatcgtt
    20041 gtataggaaa cttcaaataa aatagcatcc tgacttatcg gatctactaa ctggatcaga
    20101 ttgccaaaat catctacctt tgctacggtg agatccaaag tagaaactaa ataatgaaat
    20161 agatccttta taacttcaac atctgtagca tccccttcta aacttgcaac aggatactcc
    20221 aactcaattc cgacaaacaa ttcaggattt tctttaatat ttttcaaata ccgatgtttt
    20281 aataaatcga tagaacaaga catactaccc tacactttct taatctaaat aaaatttgaa
    20341 taactataat tataccaaaa ataatataaa aaaggaacga agaataacaa cgttcctaac
    20401 actatactat accggcggcc ggggtcgaac cggcacgtcc ttgcggacac tggattttga
    20461 gtccagcgcg tctgccaatt ccgccacgcc ggcaaatagt aactggggta gctggattcg
    20521 aaccaacgca tgagggagtc aaagtccctt gccttaccgc ttggctatac cccaataata
    20581 taaaataggc gagtgatggg gatcgaaccc acgcatgcca gagccacaat ctggtgtgtt
    20641 aaccacttca ccacacccgc cataattcta ttaacacggg cagtaggaat tgaacccaca
    20701 ctgaaggttt tggagacctt agttctacct ttaaactatg cccgtaaaat ggaaggggag
    20761 ggattcgaac ccccgaaccc gaaggagcgg atttacagtc cgccgcgttt agcct
//
LOCUS       DAVBCA010000039        20780 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.039, whole genome shotgun sequence.
ACCESSION   DAVBCA010000039 DAVBCA010000000
VERSION     DAVBCA010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20780)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20780)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20780
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.039"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            398..1091
                     /locus_tag="VQU19_001369"
                     /pseudo
     CDS             398..1091
                     /locus_tag="VQU19_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809626.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            1147..1419
                     /locus_tag="VQU19_001370"
     CDS             1147..1419
                     /locus_tag="VQU19_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase"
                     /protein_id="HET2480608.1"
                     /translation="MFLLFSALVGMLSQLKEVPESVFLQETVEENHLVNVYSVLEVIS
                     TLAFSVFVLLMSYITESFGISISFWLSAICLMIEAILIYIRRDYFK"
     gene            1733..1864
                     /locus_tag="VQU19_001371"
     CDS             1733..1864
                     /locus_tag="VQU19_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HET2480609.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            1885..3435
                     /gene="dltA"
                     /locus_tag="VQU19_001372"
     CDS             1885..3435
                     /gene="dltA"
                     /locus_tag="VQU19_001372"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HET2480610.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFVQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMIMDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGVTHFYFDG
                     EELTVKTAQKLRKRFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEGLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            3432..4676
                     /gene="dltB"
                     /locus_tag="VQU19_001373"
     CDS             3432..4676
                     /gene="dltB"
                     /locus_tag="VQU19_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HET2480611.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMWGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            4690..4929
                     /gene="dltC"
                     /locus_tag="VQU19_001374"
     CDS             4690..4929
                     /gene="dltC"
                     /locus_tag="VQU19_001374"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HET2480612.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            4922..6190
                     /gene="dltD"
                     /locus_tag="VQU19_001375"
     CDS             4922..6190
                     /gene="dltD"
                     /locus_tag="VQU19_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HET2480613.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKEELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            6345..6785
                     /gene="adcR"
                     /locus_tag="VQU19_001376"
     CDS             6345..6785
                     /gene="adcR"
                     /locus_tag="VQU19_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HET2480614.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            6785..7489
                     /locus_tag="VQU19_001377"
     CDS             6785..7489
                     /locus_tag="VQU19_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HET2480615.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYCVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNTHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            7482..8288
                     /locus_tag="VQU19_001378"
     CDS             7482..8288
                     /locus_tag="VQU19_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HET2480616.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGRSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            8298..9803
                     /gene="adcA"
                     /locus_tag="VQU19_001379"
     CDS             8298..9803
                     /gene="adcA"
                     /locus_tag="VQU19_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HET2480617.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKVTFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNVAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(10923..11696)
                     /locus_tag="VQU19_001380"
     CDS             complement(10923..11696)
                     /locus_tag="VQU19_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET2480618.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCIYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTLPDQKLLDAVELFDGEWVSDIQ"
     gene            11872..13275
                     /locus_tag="VQU19_001381"
     CDS             11872..13275
                     /locus_tag="VQU19_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HET2480619.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLSQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKKE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPILTTESFSYGF
                     TNEVGKDGVITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGLTEATAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            13390..14028
                     /locus_tag="VQU19_001382"
     CDS             13390..14028
                     /locus_tag="VQU19_001382"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HET2480620.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMELMAEKFKTYGQRK"
     gene            14040..14480
                     /locus_tag="VQU19_001383"
     CDS             14040..14480
                     /locus_tag="VQU19_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HET2480621.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            14473..14904
                     /locus_tag="VQU19_001384"
     CDS             14473..14904
                     /locus_tag="VQU19_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET2480622.1"
                     /translation="MFNRGILVASHGDFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVDELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISNYDSKINLEEIVHNAQNSLFNVKQQLNVEEEENLCL"
     gene            14895..15365
                     /locus_tag="VQU19_001385"
     CDS             14895..15365
                     /locus_tag="VQU19_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET2480623.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            15390..16163
                     /locus_tag="VQU19_001386"
     CDS             15390..16163
                     /locus_tag="VQU19_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET2480624.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            16160..16960
                     /locus_tag="VQU19_001387"
     CDS             16160..16960
                     /locus_tag="VQU19_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET2480625.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            17019..19313
                     /locus_tag="VQU19_001388"
     CDS             17019..19313
                     /locus_tag="VQU19_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HET2480626.1"
                     /translation="MKLWYKKAASNWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTMFATPRDQSHYELLGELYIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKDCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPVNLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPKTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQEREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRI
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            19323..>20780
                     /locus_tag="VQU19_001389"
     CDS             19323..>20780
                     /locus_tag="VQU19_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480627.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLH"
BASE COUNT         6450 a         3391 c         4377 g         6562 t
ORIGIN      
        1 ctactcgatt aactcccctg aaatttgttt taattatgca aatttcacgt atttttgatg
       61 ctgagacgac gatcctggga acttttcaga tatttttttg actatctaaa atctatcatt
      121 agaaaagctt agagcgccaa aggatttgag cgtttttctg atttttaaga ctttttccca
      181 gtctcttttt cgattgaaga tgtaattatt ctactaacta acttcttagt actagccaac
      241 aacgataatc ataattcctc ctaaaattag gaataataaa ggcaatagtt tttgtttttt
      301 catgtaaaaa acctcacttt tgttttctgc tattttatgc taaaatatta aaaatcaaat
      361 ttaattccaa agtttgtaac taaaggggga gcgctacatg tctaattcat ttgtcaagtt
      421 gttagtctct caattatttg caaatttagc agatattttc tttagagtaa caatcattgc
      481 taacatatac attatttcaa aatcagtaat tgccacatca ctagttccta tcttaatagg
      541 aatatcctct tttgttgcga gtcttttagt tccgttggtt actaaaaggt tagcgctaaa
      601 tagggtttta tctttatctc aatttggaaa gactatatta ttggcgatac tggtaggaat
      661 gtttaccgta atgcaatccg tagcgccttt ggtgacctat ctatttgttg ttgcaatttc
      721 catactagat ggttttgcag cacccgtttc ctatgctatt gtgccacgct atgcgaccga
      781 tttgggtaag gctaattcag ccttatcaat gactggtgaa gctgttcaat tgataggttg
      841 gggattaggt ggactcttgt ttgcaacaat tggtctgtta cctaccacgt ttatcatttt
      901 agtcttgtat atcatttcta gctttctgat gttatttctt cctaacgctg aagtggaggt
      961 gttagagtca gaaactaatc ttgaaatttt gctcaaaggt tggaagttag ttgctagaaa
     1021 tcctagatta agactttttg tatcagcaaa tttattggaa attttttcaa atacgatttg
     1081 ggtttcttcc attttgtagc tatggcaata gtgacactga ctattctata ttttccaaac
     1141 gcacagatgt ttttattatt ttcagcttta gttggtatgt tatcgcaact aaaagaagtt
     1201 cctgaaagtg tatttcttca ggaaacagta gaggaaaatc atttagttaa tgtctattcc
     1261 gttcttgaag tgatttctac attagcattt tcagtatttg ttttgctaat gagctatatt
     1321 actgagagtt ttggtattag catcagtttt tggctatcag ccatttgtct gatgatagaa
     1381 gctattttaa tttatatcag acgagattat tttaaatgag agagtggtta aaaagtcttt
     1441 aaaaatcaga aaagcgcata gtatcaggtg ttgaaaaaac ttgatattgt gtgttttatt
     1501 atgggaagat ttacttcatt gtctcctgaa atggagtttt gaagcaggat cactctattt
     1561 gaaaatatac atagaaaaac tgtataatcc ttaaaataag ctgaaatcta ttggaaacat
     1621 acggtaaaca attgaaaagg tactatataa agtggtacaa tggtagaaaa ataagctagt
     1681 aagaatcact cttattttag cgaaaaatta cagaaatgaa tggtttttct tgatgaaaca
     1741 gagaaaagaa ttgtacctct ttcttggtcg gacagccttg tattttctta tctttctagg
     1801 gctgctttac ttctttagct atcttggtca gggtcaagga agctttatct ataatgaatt
     1861 ttaacttgaa ggagaatccc tattgtgtca aataaaccaa tagcagatat gattgaaacc
     1921 attgagcatt ttgctcagac acagcctagc tatcctgtct ataatgtttt ggggcaggaa
     1981 cacacttatg gcgatttaaa ggctgattcg gatagtttgg ctgcagtcat tgaccaacta
     2041 ggcttgcctg agaagtctcc tgtggttgtt tttggtggcc aagaatatga aatgttggca
     2101 acctttgtag cgctgactaa gtcaggtcat gcctacattc caattgatag ccattcggcc
     2161 ttggagcgag tttcagctat tttagaagta gcagagccaa gcttgattat tgccatttca
     2221 gcctttccct tggagcaggt ttctacacca atgataaatc tagctcaggt tcaagaagcc
     2281 tttgttcaag ggaataacta tgaaatcacg catccagtca agggagatga taattactac
     2341 attatcttta cttctggtac gactggtaag cctaagggag tgcagatttc acatgataat
     2401 ctcctcagct ttacaaactg gatgattatg gataaggaat ttgcgacacc gagtcgtccg
     2461 caaatgctgg cacagccacc ttattctttt gacttgtctg tcatgtattg ggcaccgacc
     2521 ttggcacttg gtggtacgct tttcactctt ccttcagtca tcactcagga ctttaagcaa
     2581 ctctttgcgg ctatcttttc attgccaatc gctatctgga catcaacacc atcctttgca
     2641 gatatggcca tgttgtctga atacttcaac agtgagaaaa tgcctggagt cacgcatttc
     2701 tactttgatg gtgaagaatt gacggtcaaa acagctcaaa aactgcgcaa gcgtttccca
     2761 aatgcccgta tcatcaatgc ttacggccca acagaagcga cagtagctct gtcagcagtt
     2821 gccgtgacag acgagatgtt agcgactctc aaacgcctac caatcggcta taccaaggct
     2881 gattctccaa cctttatcat tgacgaggaa ggaaataaac tgccaaatgg cgaacaggga
     2941 gaaatcattg tttctgggcc agctgtttca aaaggttata tgaacaatcc tgaaaaaaca
     3001 gcagaagcct tctttgagtt tgaaggtctg ccagcctatc acacaggcga tgtgggaacc
     3061 atgacagatg agggcttgct tctctacggc ggacgcatgg acttccagat taagtttaac
     3121 ggttaccgca ttgagttaga agatgtctct caaaacctca acaagtctcg ctttatcgaa
     3181 tctgctgtcg cagtaccgcg ctataacaag gaccacaagg tacaaaatct attggcttat
     3241 gtcatcttaa aagacggtgt tcgtgagcag tttgagcgag atatcgatat taccaaggcc
     3301 atcaaggaag acctgacaga catcatgatg tcctatatga tgccatctaa attcctttac
     3361 cgagacagtt tgccactgac tccaaatgga aagattgaca tcaaaggatt gattaacgag
     3421 gtgaataaga gatgatggag ttttttcaac agcttcctca tttagagcca tatggcaatc
     3481 ctcagtattt tgtttatgtg attgctgcaa ccttgcccat ctttataggt ctctttttca
     3541 agaaacgctt tgcctggtat gaagtgttgg taagtctctt ctttattgtc accatgttgg
     3601 tgggtggaaa gaccaatcaa ctagctgcct tgggtattta cctttgctgg gaaatattgc
     3661 tcctgctttt ctacaagcat tatcgaaaaa gcaaggatgg caagtgggtc ttctacttag
     3721 ttagttttct gtccctactt ccgattatct ttgtcaaggt gcaaccagct atcaatggaa
     3781 cgcagtcttt gcttgggttc ttgggaattt cttatcttac ctttcgttcg gttgggatta
     3841 tcatcgagct gagagatgga gtgattaagg attttaccct ctgggaattc ctccgtttcc
     3901 ttctcttcat gccaactttc tcgagtggtc caatcgatcg ctttaagcga tttaatgaaa
     3961 attatcaggc tattcctgag cgagatgagt tgatggatat gctggatgaa tctgtccgct
     4021 atatcatgtg gggctttttg tataagttta tcctagctca tgttttagga gagaccttac
     4081 tacctcctct gaagaattta gccttgcagt caggtggctt ctttaatctc tatgccttgg
     4141 cagttatgta tacttttggt ctggagctct tctttgactt tgcaggttat tctatgtttg
     4201 ctttggccat ctcaaacttg atgggaatcc gtagccctat caactttaac aagccctttt
     4261 tatcaaggga tttaaaggag ttttggaatc gctggcatat gagtctgtcc ttctggttcc
     4321 gtgactttgt ctttatgcga atggtgatgg tgttaaccag aaagaaagtc tttaaaaatc
     4381 gtaatgtaac ctcaagcatg gcctacattg taaatatgct gattatggga ttttggcatg
     4441 gtgtgacctg gtactatatc gcctatggac tctttcatgg actaggcttg gtcatcaatg
     4501 atgcctgggt tcgcaagaaa aaaacactca ataaggaacg gaaaaaagca gggaaggctg
     4561 ccctacctga gaatcgctgg attcagttgc ttggcatggt tgtcactttc catgttgtca
     4621 tgttgtcatt cttaatcttt tctggattct tgaataatct atggtttaaa aaataaaagg
     4681 aaataaaata tggatatcaa atcagaagtt atcgaaatta ttgatgagtt gtttatggaa
     4741 gatgtttctg acatgatgga tgaagatctt tttgatgcag gtgtcttgga tagtatggga
     4801 acggttgagt tgattgtgga gattgagaac cgttttgaca ttcgtgtccc tgtaacagag
     4861 tttggtcgtg acgactggaa tacagctaat aaaatcatag ctggtattgt ggagctacaa
     4921 aatgcttaaa cgcttatgga tgatcttcgg accggtcttg atcgctggtt tgttggtttt
     4981 tctgctcatt ttcttttatc ctactgagat gcatcataat ctaggagctg aaaagcgttc
     5041 agcagtggct actactatcg atagttttaa ggagcgaagt caaaaagtca gagcactatc
     5101 tgatccaaat gtgcgttttg ttcccttctt tggctctagt gaatggcttc gttttgacgg
     5161 tgctcatcct gcggtattag ctgagaaata caatcgttcc taccgtcctt atcttttagg
     5221 acagggggga gctgcatcgc ttaaccaata ttttggaatg caacagatgt taccacagct
     5281 ggagaataaa caagttgtgt atgttatctc acctcagtgg ttcagtaaaa atggctatga
     5341 tccagcagcc ttccagcagt attttaatgg agaccagttg actagttttc tgaaacatca
     5401 atctggggat caggctagtc aatatgcagc gactcgctta ctgcaacagt tcccaaacgt
     5461 agctatgaag gacctggttc agaagttggc aagtaaagaa gaattgtcga cagcagacaa
     5521 tgaaatgatt gaattattgg ctcgttttaa tgaacgccaa gcttcctttt ttggtcagtt
     5581 ttcggttaga ggctatgtta actacgataa gcatgtagct aagtatttaa aaatcttgcc
     5641 agaccagttt tcttatcagg caatagaaga tgttgtcaaa gcagatgctg aaaaaaatac
     5701 ttccaataat gagatgggaa tggaaaatta tttctataat gagcagatca agaaggattt
     5761 gaagaaatta aaggattctc agaaaagctt tacctatctc aagtcgccag agtataatga
     5821 cttgcagttg gttttaacac agttttctaa atctaaggta aacccgattt ttatcattcc
     5881 acctgttaat aaaaaatgga tggactatgc tggtctacga gaggatatgt accaacaaac
     5941 ggtgcagaag attcgctacc agttagaaag tcaaggtttt accaatatag cagatttttc
     6001 taaggacggc ggggagcctt tctttatgaa ggacaccatt caccttggtt ggttgggttg
     6061 gttggctttt gacaaggcag ttgatccttt cctatccaat cccacaccag ctccgactta
     6121 ccatctgaat gagcgctttt tcagcaaaga ttgggcgact tatgatggag atgtcaaaga
     6181 atttcaatag ataatataat atagaagagt tcaagaatga aactagtttt cacgtttttt
     6241 cttgactctt tttttgcttg tgatataatt aactggtaaa caaaatgtca aagaatagta
     6301 tttttctctt aaaaaagaga agtctaaaag gaaaggagtc agatatgaga cagctagcaa
     6361 aggatatcaa tgcttttttg aatgaggtga ttttgcaggc ggaaaatcag catgaaatcc
     6421 taataggtca ttgcactagc gaggtggccc tgaccaatac tcaggagcat atccttatgc
     6481 tcttgtcaga ggaatcttta acaaattcag aattggcccg tcgtctcaat gtcagtcagg
     6541 cggcagttac caaggccatt aagtctttgg tcaaggaagg gatgttggaa acatctaaag
     6601 attctaaaga tgcgcgtgtg attttttatc agttgactga cttggctcgt ccaatcgctg
     6661 aggagcacca ccatcaccat gagcatacac ttttaaccta tgaacaagtg gcgactcagt
     6721 ttactccaaa tgaacaaaaa gtgattcagc ggtttttgac tgctttagta ggagaaatca
     6781 aataatgaga tatattacgg tagaggattt gtccttctat tatgataagg aacctgttct
     6841 tgaacatatc aattattgtg ttgatagtgg ggaatttgtt accttgactg gggaaaatgg
     6901 agcggctaag acgacgctca tcaaggccag tcttggaatt ctgcaaccac gcattggaaa
     6961 ggtggctatt tcaaagacaa atacgcaagg taagaaattg agaatagcct atcttcctca
     7021 acaaattgcc agttttaatg ctggttttcc aagtacggtc tatgaatttg tcaagtcggg
     7081 tcgctatccg agaaaaggct ggttccgtcg tttgaatact catgatgagg agcatatcaa
     7141 ggctagtctg gactcagttg gcatgtggga acatcgagac aaacgcttgg ggtctctatc
     7201 tgggggacaa aagcagcgag cggtaattgc gcgtatgttt gcttctgacc ctgatgtgtt
     7261 tatcctagac gagccgacaa cggggatgga tgcaggaagt aaaaatgaat tttacgaact
     7321 catgcaccac agcgcccatc atcatggcaa ggctgttttg atgattaccc atgaccctga
     7381 agaagttaag gattatgcgg atcgcaatat tcatctagtc cgtaaccaag actcgccatg
     7441 gcgttgtttc aacgttcatg agaatgggca ggaggtgggc catgcttagt ttattatctt
     7501 acgactttat acaacgcgcc tttttggcgg ttattgctat gagtcttttc tcaccggtat
     7561 tgggaacctt cctcatcttg cgtcgtcaga gtttgatgag tgataccctt agccacgtct
     7621 cactttcagg tgtagccttt ggtctggttt tggggatttc tccaactgtt tctactattg
     7681 ccattgtctt gattgcggcg gtctttctgg agtatctccg tacggtttac aagagcttta
     7741 tggaaatcgg gacagctatc ctcatgtcaa caggtttggc tgtttctctg attgtcatga
     7801 gcaagggtag aagctcgagt tcaatgagtt tggaccaata tctctttggt tcgatcgtga
     7861 ctatcagtga agaacaggtc atttccctct ttgtcattgc ggcggttgtt ttgattttga
     7921 cctttctctt tcttcgtcct atgtatatct taacttttga cgaagatacg gcctttgtgg
     7981 atggcttgcc agttcgtacc atgtccattc tttttaacat ggtgacaggg gtggctattg
     8041 cccttatgat tcctgcagca ggagctcttc tggtatcgac cattatggtc ttgccagcta
     8101 gtattgccct gcgtctgggg aaaaacttta aatcggttat gctgcttgcc agtgcgattg
     8161 gctttttggg aatggtagca ggactttaca tttcctacta tgcagaaaca cctgcaagtg
     8221 caagtattac cattattttt gtaactgtct ttatactaat cagtttagta agacgtttta
     8281 tcaaatagga gacgaacgtg aaaaaaatta gcttattact agccagtcta tgtgccttgt
     8341 ttttagtggc ttgttccaat caaaaacagg cagatggtaa actcaatatc gtgacaacct
     8401 tttaccctgt ctatgaattt accaagcaag tcgcaggaga tacggctaat gtagaactcc
     8461 taatcggtgc tgggacagaa cctcatgaat acgaaccatc tgccaaggca gttgccaaaa
     8521 tccaagatgc agataccttc gtttatgaaa atgaaaacat ggaaacatgg gtacctaaat
     8581 tgctagatac cttggataag aaaaaagtga aaaccatcaa ggcgacaggc gatatgttgc
     8641 tcttgccagg tggcgaggaa gaagagggag accatgacca tggagaagaa ggtcatcacc
     8701 atgagtttga cccccatgtt tggttatcac cagttcgtgc cattaaacta gtagagcaca
     8761 tccgcgacag cttgtcagca gattatcctg ataaaaaagt gacctttgag aagaatgcag
     8821 ctgcctatat cgaaaaattg caagccttgg ataaggctta cgcagaaggc ttgtctcaag
     8881 caaaacaaaa gagctttgtg actcaacacg cagcctttaa ctatcttgcc ttggactatg
     8941 gactcaaaca agtcgcaatc tcaggacttt ctccagatgc agagccatca gctgctcgct
     9001 tggcagaatt gacagagtat gtcaagaaaa ataaaatcgc ctatatctat tttgaagaaa
     9061 atgcctcaca agcccttgct aacacacttt caaaagaagc aggtgtcaaa actgatgtcc
     9121 tcaatccttt agaaagtctg acagaagagg acaccaaggc tggagaaaac tacatttccg
     9181 tgatggagaa aaacctcaag gctttgaaac aaacaacaga ccaagaaggc ccagcaatcg
     9241 aacctgaaaa ggcagaggat accaagacag tccaaaatgg ttacttcgag gatgcagctg
     9301 tcaaggaccg caccttgagt gactatgcag gtaactggca atcagtttat cctttccttg
     9361 aagacggcac gtttgaccaa gtctttgact acaaggctaa gttgactggt aagatgaccc
     9421 aggctgagta caaggcttac tatacaaaag gctatcagac agatgtgact aagattaaca
     9481 ttactgataa tactatggaa tttgttcaag gtggacaaag caagaaatac acttacaagt
     9541 atgtcggtaa gaaaattttg acttacaaga aaggcaatcg tggcgtgcgt ttcctctttg
     9601 aagccacaga tgctgacgct ggacaattca agtatgttca gtttagtgat cacaatgttg
     9661 ccccagttaa ggcagaacat ttccatatct tctttggagg cacaagccaa gaagccctct
     9721 ttgaagaaat ggacaactgg ccaacctact acccagataa cctatctggc caagaaatcg
     9781 cccaagaaat gttggcgcat tgatgagaaa tcgactagtt cataagagct agtcggtttt
     9841 ttgatactag atggctaact tcattataga cctttcagaa ctttaaacaa taaataaaac
     9901 tcttgaaata tctgggctta tatgctagaa tgtagttagt gtataaggtt cattagaaca
     9961 ccaaagcccc taactagtgc catagttaag ggcttttttg acgtatctta gcgatttaac
    10021 gggtgtttat aggctagtca gtcggtctac ttcttaccat ctagccattt gcagacgaaa
    10081 tacaagataa ttccagctat aacatctgct ataatagtaa gagcaagctc tggtataagg
    10141 ctcattagtt tcacctcctc tcacgaaccc ataggaacgt aatcggtaac cgatgacaaa
    10201 aatagtatac cacactaaat ttagatcatc aacctcactt aatgcttgaa ctattgtaga
    10261 ttatatgcta aaatgtagtt aattgataag gttcattaga acaccaaagc ccctaactat
    10321 ggccgtagtt aagggctttt ttgacgtatc ttagcgattt aacgggtgtt tataggctag
    10381 tcactcggtc tactccttac tatctagcca tctgcagacg aaatacaaga taattccagc
    10441 tataacatcc gctataatag taagagcgag ctctatgata aggctcatta gtttcacctc
    10501 ctctcacgaa cccataggaa cgtaatcggt aaccgatgac aaaaatagta taccacaata
    10561 tatttagatc atcaaggtca cttaattctt gaaatatagg gtctaggcga caaagtcttt
    10621 aaaatcagaa aaacgcataa tatcaggtgt gcaaaaactt gatactatgc gttttattgt
    10681 gggaaggttt actccatttt ctcctgaaat tgagtttttg tccagcctct gtttttagaa
    10741 ttgctaagaa aataatgtca tgtggtgaat atttgtaaat cagtcagcag acagaacgaa
    10801 tactcttcga aaatctcttc acatcatgtc agcttcgtct tgccgtgtcc atgggggact
    10861 tgacttgatc agttttcaaa tctgtacttt gagcaagctg agactagctt cctatttgat
    10921 tttcattgaa tatcagaaac ccattctcca tcaaataatt cgactgcgtc taataatttt
    10981 tggtctggca aggtgtcaga aataaaggtt gtgtatttgg agaggggatt aattttaaaa
    11041 aatccagtct tgtaaaattt agaactatca atcagtaaga tggtttcatg ggctttgtca
    11101 ataatattct tttttgaaat agcttggctg agagaagctt cataaacata ttggtcatca
    11161 atacctcttg ctgaacaaaa tgctaaatcg atattaaaat gatctaataa agaattttcc
    11221 ttatcatagt tgaccacgga acaggattga tgtttgacct cgccagatgt gataaagatt
    11281 ttggagctat ctttaacagt ttcagatagg gtttgtgcag tatgtaaacc atttgtaaaa
    11341 ataatcaaat tatcaagttc agaaagatag ggacaaagtt cgtagacagt agtactagaa
    11401 tctagataga tacacatacc agaccgaata aagtctttag cgagactagc gattagtctt
    11461 ttttgcctag tactttctcc ttcccgtatt tgatgagaaa gttcaattgt gttcatagag
    11521 gacagggtca cgtatccgtg ctttcttttg ataagacctt gattttctaa gaaaattaaa
    11581 tcacgacgta aggtacttgt gctggagaaa gtgatttctg ccagctcttt tacggcaatt
    11641 ctttttttct ttttaataat ttcaatcaat tcaagtacac gttcatcttt tatcataagc
    11701 tcctcctaat ttatcatttc aactatatta tagcacaaat tggaggaatt tgaattattt
    11761 ttatgaatat tgggttaaca tttgaacatt attcaagtaa gcgttcacat attgaaaaaa
    11821 taaaacgtgg ggattataat aaagttaatc aaggacgaag agagaagaaa aatggaagcg
    11881 gttttagcaa tagatttagg tgcgacttct ggaagagcaa tcgttggtta cctttctgaa
    11941 aataaactag taatggaaga aataaatcgc ttttctaatc tacctattag agtaaaaggg
    12001 catttatctt gggatattga ctttctacta gctaaaattc ttgaaagtat ccgcttggct
    12061 aatactagtt acaagatttt atctatcggt attgacacat ggggagttga ttttggactg
    12121 attgataatg aaggtaagct gttatcacaa cctgttcatt atcgtgatga aagaacaaag
    12181 ggagtgttaa aggaaatatc tgaaatgact gaattagaaa aactgtattc agagacagga
    12241 aatcagatta tggagataaa taccttgttt caactcttta aggcacgtca agaatctcct
    12301 gactctttct ataagaccaa taagattctt ttaatgccag atttgtttaa ttatctcttg
    12361 acaggtaagt ttgctacaga aaaaagcatt gcttcaacaa ctcaattatt tgatcctagg
    12421 agtcaaaatt ggaatcagaa tatcttaaaa ctatttgaat tggattcatc tttacttcct
    12481 gaaattgttt cagagggaaa tgttcttgga aggataaaaa aggagtatgg tttaggcgat
    12541 attcctgttg tgaatgtttg tagtcatgat acagcaagtg cgattgtctc agtacctaag
    12601 acagaaggta gtttatttat ttcatcaggt acttggtctt tggttggagt ggaacttact
    12661 tcaccgattc ttactaccga atccttcagt tatggattta caaatgaagt cggtaaagat
    12721 ggagtgatta catttctgaa gaattgtaca gggttgtgga tcatagagga actaagacgt
    12781 tcatttgaac gaagagggaa agcctattct tttgatgata ttaggacaat ggtggagaaa
    12841 gaaaaagaaa atcttcctct gattgatact gaatcaactg aatttgcaac agaatctgat
    12901 atgcacaaga ctttgacaga atatctagct tatcatcatg aaactagaga gtggacagat
    12961 ggacaactat ttaagattgt ttatgaaagc ctagctgaaa cgtataggaa agcgatagag
    13021 ttattagaag aactaactca taaggtttat aagaggatat atgtgattgg aggaggtgct
    13081 agagccagtt attttaacca aatgattgct gatagaactg gtaaagaggt tcttacaggt
    13141 ttgactgagg ctacagctgt ggggaatatt gttgtgcagc tcatagctat gggacaatta
    13201 aaagggatgg aagaggctca ccatgttatt gaggagtttc tacaattaga gagttattac
    13261 tcccaaaaga attaaaaaga ttgagagttt gtaaatttgc ctccctcccc cttcttagct
    13321 tttgtgcagg aaggggggat aattggtgaa ttgaaaaata tttagtgttt tgatatgagg
    13381 aggacaagga tgtcagatgt aaaacaagaa ttaattaaat atggtaagaa gctagtagaa
    13441 acagatttga cgaaaggaac aggtgggaat ctcagcgttt tcgatcgtga aaaacaattg
    13501 atggcaatta ccccgtcggg tattgatttc tttgaaatca aagaatccga tattgtagtg
    13561 atggatatta atggaaatgt tgtagaggga gaacgcttgc catctagcga atggtatatg
    13621 catttgattc aatatcaaac tcgtgatgat atcgatgcaa ttatccatgc tcatacaact
    13681 tatgcaacag tattagcttg tctcagagaa ccacttccag cgagtcatta tatgattgca
    13741 gtggcaggga aagatgttcg ggtagctgag tatgcaacat atggcacgaa agaattggct
    13801 gtgaatgcag ctaaagcaat ggaaggtcgt agagcagttt tactagcgaa tcatggaatt
    13861 ttagcaggtg cacaaaattt attgaatgca tttaatattg ttgaagaagt tgaatattgt
    13921 gcaaaaattt attgtttagc taagaatttt ggagagccag tagttcttcc tgatgaggag
    13981 atggaattga tggcagaaaa atttaaaaca tacggtcaga gaaaataggg aggatattaa
    14041 tgttaaaaca tataccgaaa aatatttctc cagatttatt gaagacttta atggaaatgg
    14101 gacatggaga tgaaatagta ttagctgacg cgaattatcc ttctgcctca tgtgcaaata
    14161 agctaattcg ttgtgatggc gtaaatattc cagaattatt agattccatt ctgtatttaa
    14221 tgccattaga tagttacgtc gatagttcaa ttcagtttat gaacgttgtt tcgggtgatg
    14281 atattcctaa gatatggggt acctatagac agatgattga aggtcatggt acagatctta
    14341 aaacgattac ttatcttaga agagaagact tttatgaacg tagtaagaaa gcttatgcta
    14401 ttgttgctac aggagaaact tcactttatg ctaatattat ccttaagaaa ggagtagttg
    14461 ttgaaagaga aaatgtttaa tagaggaatt ttagttgcca gtcatggtga ttttgctagc
    14521 ggagctctca tgaccgcaga aatgtttgtt ggtgagacaa caaatgatag agttaggaca
    14581 ttaggtttga tgcctggaga gaatattgta gagtttgagc attattttaa aaatcaagtg
    14641 gatgaactgt tagactcaaa tcaagaggtt atcgttttga ctgacttgat tggaggaagt
    14701 cctaataatg tggctttgtc acggttttta aatttggatt cagttgatat tgtaacaggg
    14761 tttaatattc ctctcctagt ggaattaata tcaaattatg attcaaaaat caatttagaa
    14821 gaaattgttc acaatgctca aaatagtttg tttaatgtta aacaacaact taacgtagag
    14881 gaggaagaaa atttatgtct atagagtttg ttcgtattga tgaccgtctg gtacatggtc
    14941 aagttgtcac tacgtggcta aaaaagtatg atattgagca agttatcatt gttaatgatc
    15001 gcatctcaga agataaaaca cgacaatcta ttttaaagat ttctgcacca gtaggtttaa
    15061 aaattgtttt ctttagtgta aaacggtttg tggaagtttt aaactctgtg ccaataaaaa
    15121 agagaacaat gctgatatat acaaatccaa aagatgtgta tgattctatt gaaggaaatt
    15181 taaaattgga gtacctcaat gtaggacaga tgagtaaaac ggaggaaaat gaaaaggtaa
    15241 cgggaggtgt agctctaggt gaagaagaca aatattattt taagaaaata gttgataagg
    15301 gaacgagagt tgaaattcaa atggttccta atgataaagt tacaatgttg gaaaaatttt
    15361 tataaaaata atttaaggag gtacagtata tgctattcac acaagcatta ctggtgacat
    15421 tagttgggat tattgccact attgactata atggaccgtt atttatgatt caccgtccgt
    15481 tagttacaag tgcaatggtt ggcttagtct taggagattt cacccaaggt gttcttattg
    15541 gttcagctct tgaattaact tggctcggtg taacaggtat tggaggttac actccaccag
    15601 atactatttc aggtgcgatt attggtactg catttggtat tttatctggt caaggagaaa
    15661 ctgctggtat cgctatagca gttccaattg cagttgctac ccaacagttg gatgttcttg
    15721 caaaaacttt agatgtttat tttgtgaaaa aagctgataa tgatgctaaa aacggagatt
    15781 attcaaagat cggtttttat cattattcaa gtttggtttt aatcacgtta tttaaaattg
    15841 taccaatttt cctagctatt atgcttggag gggaatatgt ggcagacttg tttgctaagg
    15901 ttccaccaat cgttatgcag ggacttaact ctgcaggtgc tttactacct tcaattggtt
    15961 ttggtatgct tttaaatatg atgctcaaga aaaatatgtg ggtattcttg ttgattggat
    16021 tcatttgttc tgtgtatgga ggaatgtcaa ccattgggat ctcactagtt ggtattgcgg
    16081 tagcatactt ctacgatatg attggaagta aaccacaaga aacaacttca agtagtgatg
    16141 ttgaggagga tcttgatcta tgatgaataa taaagtaact aaagttgaac ttaaaaaagt
    16201 tttcaaacga agttttatgt atggttcttc atggaactat gagagaatgc agaacctagg
    16261 ttttctatat acaattcttc cagtattgaa aaaactatac ccagacaaag attcagcttc
    16321 tcctgcaatg aaacgtcacc ttgagttttt caatactcat caaacagcgg caccatttat
    16381 tcttggagtt acttccgcta tggaagaaca agaaggaaat gaaggtgcag cttcaattac
    16441 tggtattaaa gttggcttga tggggccact ggctggtcta ggagatagtt tgttctggct
    16501 gacactagtt cctatctgtt ttagtattgg tgcgtcttat tctaaagacg gcggtgcttt
    16561 aggtatcttt atcgccttaa tattgtttaa tattattaat attcctgtta aatatttcgg
    16621 tttgaaatat gggtatacta agggttctag tcttatccaa gaaaataata caaaaggaac
    16681 attgaatcgc gttacgagta tggcgacagc attagggcta gtactagtgg gtggtttgat
    16741 tccatcaatg gttggtatta attttggatt agaatttaag cagggggaac ttgttatttc
    16801 tgttcaagaa atgattacaa aattaattcc aggatttatc cctatggctt tgactttatt
    16861 aatgtgtaaa ttaattagaa aaggaaagaa tccggttgta ctaatcttta gtgttatggc
    16921 tattggagtt atcctagttg ttttaggaat tttgaagtag tagaaagtgt ggaggtggta
    16981 tttgggatat cacctccatt ttggaagaga ggtaaagagt gaaattatgg tataagaaag
    17041 ctgcctcaaa ttggaatgaa gccttgccga ttgggaacgg tcatttaggt ggtatgattt
    17101 atggttcagc tacaaaagaa tgtattcaac taaacgatga gactatttgg tatagaggaa
    17161 agtcagatag aaataatcca gactcactat tgcatcttaa aaaaattcgg gaatatcttt
    17221 tagatggaga aattcagaaa gccgaagaat tgataaagtt aacaatgttt gctaccccaa
    17281 gagatcaaag ccactatgaa ttacttgggg aactttacat tgagcatata gatattcagt
    17341 cttgtgctct ttcattgtat gaaagagagc tagatttaga tacagctatt tctaatgttg
    17401 tgtttgagcc taatagttgt aatttacaaa taaaaagaga atattttacg agttttaata
    17461 agaatatttt atgttgccgt atagtgtcat cagttcaaaa cacattaaat ttaaacatta
    17521 atttgggtag aaataaacgg tttaatgacg aagtatctaa actggattca agtacaattt
    17581 taatgtcggc ctctgctgga ggtagaaaag gtgttcagtt taaagtagta tgtcattcta
    17641 aagttacgga tggtgaagta agtgtattgg gagagacaat agttattcgg aatgctacag
    17701 aggtatttct ttatctcaaa tcaatgacgg attattgggg aaatatagat atttcttctc
    17761 ttcagggaga atttagtagt attgattact ttacagaaaa agatgaacat gtaaaaaaat
    17821 atcaggagca atttaataga gttgatttta aactagacta tagtaaagat tgtcttagca
    17881 ttccaacgaa tctacttctt gaaaacacta aaaagtatag taactacttg actaacttgt
    17941 tatttcatta tggaagatat ctgttaatat cgtctagtca accgaatggt ttacctgtca
    18001 atcttcaagg aatatggtgt gatgaattaa atccaatttg gggttctaaa tatacgatta
    18061 atattaatac tcaaatgaat tattggatgg taggtccatg tgatttacca gaagtagaat
    18121 atccattatt tgatatgctc gaaagaatga gagaaccggg aagactaacc gctaagaaaa
    18181 tgtatggagc tagaggtttt acagcacatc ataatacgga tggttttggc gatacggctc
    18241 cccaatctca tgccatgggg gctgcaattt gggtattaac tattccatgg ttatgtactc
    18301 atatttggga acactattta tatttccaag atgagcgtat tcttacggaa cattttgaaa
    18361 tgataaaaga agcatttctt ttctttgaag attatttatt tgaggtggat ggctacttga
    18421 tgacaggtcc aagtgtctca ccggaaaata aatatcgctt aaaaaatggt attgaaggaa
    18481 atgcttgtct atcatctaca attgataatc aaattctaag atatttttgt gattcatgca
    18541 ttggcattgc aaaacaatta ggagacaatt cggattttat tagtcgtgtg aaggagttaa
    18601 aaaagaaact acctaaaaca aaaataggta gtaatgggca aatccaagaa tggttagaag
    18661 attatgaaga agtagagcct gggcatagac acatttcacc tctatttggg ctttatcctt
    18721 ataatgagat tgatattcat aaaactccgg aattagcaga agcagctaaa atcactatca
    18781 ataggagatt atcaaacgct aactttttat cttcacagga gagggagcaa gcgattaata
    18841 attggttagt aagtggtttg catgctagta cacaaacagg ttggagtgct gcatggctga
    18901 ttcatttttt tgcgagacta tatcaaggtg aacctgctta taaccagatt aatggtttgt
    18961 taaataatgc gactcttggc aatttatttc ttgaccatcc accatttcaa attgatggta
    19021 atttaggttt ggtgagtgga atttgtgaat tattagtaca gagccatcat aattggttat
    19081 cactaattcc agctttacct tctgcttggt cagaaggaga agtgaaaggt ttcagagtaa
    19141 gaggaggata taaggtatcg tttgcttgga aaaatgggga tataacattc ctaaaattgg
    19201 aaggaggaaa caaagatcaa aaagtaagag taagaatata tggcaaaaat actgatgtac
    19261 aaaatattga attggtattt aattcagaaa aaattattga gttaaatttt taggtataag
    19321 tcatgaataa agaaaaaata aaaagaaaat taatcacaat actgtttgta tgtattggga
    19381 tgttatgttt tggattgtta gcaggagtta aggctgataa tcgtgttcaa atgagaacga
    19441 cgattaataa tgaatcgcca ttgttgcttt ctccgttgta tggcaatgat aatggtaacg
    19501 gattatggtg ggggaacaca ttgaagggag catgggaagc tattcctgaa gatgtaaaac
    19561 catatgcagc gattgaactt catcctgcaa aagtctgtaa accaacaagt tgtattccac
    19621 gagatacgaa agaattgaga gaatggtatg tcaagatgtt ggaggaagct caaagtctaa
    19681 acattccagt tttcttggtt attatgtcgg ctggagagcg taatacagtt cctccagagt
    19741 ggttagatga acaattccaa aagtatagtg tgttaaaagg tgttttaaat attgagaatt
    19801 attggattta caataaccag ttagctccgc atagtgctaa atatttggaa gtttgtgcca
    19861 aatatggagc gcattttatc tggcatgatc atgaaaaatg gttctgggaa actattatga
    19921 atgatccgac attctttgaa gcgagtcaaa aatatcataa aaatttggtg ttggcaacta
    19981 aaaatacgcc aataagagat gatgcgggta cagattctat cgttagtgga ttttggttga
    20041 gtggcttatg tgataactgg ggctcatcaa cagatacatg gaaatggtgg gaaaaacatt
    20101 atacaaacac atttgaaact ggaagagcta gggatatgag atcctatgca tcggaaccag
    20161 aatcaatgat tgctatggaa atgatgaatg tatatactgg gggaggcaca gtttataatt
    20221 ttgaatgtgc cgcgtataca tttatgacaa atgatgtacc aactccagca tttactaaag
    20281 gtattattcc tttctttaga catgctatac aaaatccagc tccaagtaag gaagaagttg
    20341 taaatagaac aaaagctgta ttttggaatg gagaaggtag gattagttca ttaaacggat
    20401 tttatcaagg actttattcg aatgatgaaa caatgccttt atataataat gggagatatc
    20461 atattcttcc tgtaatacat gagaaaattg ataaggaaaa gatttcatct atattcccta
    20521 atgcaaaaat tttgactaaa aatagtgagg aattgtctag taaagtcaac tatttaaact
    20581 cgctttatcc aaaactttat gaaggagatg ggtatgctca gcgtgtaggt aattcctggt
    20641 atatttataa tagtaatgct aatatcaata aaaatcagca agtaatgttg cctatgtata
    20701 ctaataatac aaagtcgtta tcgttagatt tgacgccaca tacttacgct gttgttaaag
    20761 aaaatccaaa taatttacat
//
LOCUS       DAVBCA010000040        20625 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.040, whole genome shotgun sequence.
ACCESSION   DAVBCA010000040 DAVBCA010000000
VERSION     DAVBCA010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20625)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20625)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20625
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.040"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..140)
                     /locus_tag="VQU19_001390"
     CDS             complement(<1..140)
                     /locus_tag="VQU19_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2480628.1"
                     /translation="MLYVGIDIAKNKHDVTALNVPGKTVLKPLTFSNNKAGFELLDLS
                     LR"
     gene            395..1240
                     /locus_tag="VQU19_001391"
     CDS             395..1240
                     /locus_tag="VQU19_001391"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HET2480629.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            complement(1387..2448)
                     /gene="dinB"
                     /locus_tag="VQU19_001392"
     CDS             complement(1387..2448)
                     /gene="dinB"
                     /locus_tag="VQU19_001392"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HET2480630.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIRDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKSVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGVSYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILLAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSKKERGVRLLGITMTGF"
     gene            2796..5120
                     /gene="pflB"
                     /locus_tag="VQU19_001393"
     CDS             2796..5120
                     /gene="pflB"
                     /locus_tag="VQU19_001393"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HET2480631.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            complement(5487..5705)
                     /locus_tag="VQU19_001394"
     CDS             complement(5487..5705)
                     /locus_tag="VQU19_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480632.1"
                     /translation="MMSIREQDLQDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVL
                     LEGFSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(5801..6039)
                     /locus_tag="VQU19_001395"
                     /pseudo
     CDS             complement(5801..6039)
                     /locus_tag="VQU19_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397100.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(6032..6316)
                     /locus_tag="VQU19_001396"
     CDS             complement(6032..6316)
                     /locus_tag="VQU19_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480633.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            complement(6928..7098)
                     /locus_tag="VQU19_001397"
     CDS             complement(6928..7098)
                     /locus_tag="VQU19_001397"
                     /inference="COORDINATES: protein motif:HMM:NF024172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2480634.1"
                     /translation="MTKQVPKFTKDTAQLYTCKWLLYNKVTKMYDHTVVNHSVREYIT
                     DSISTNTIEETG"
     gene            complement(7748..8971)
                     /locus_tag="VQU19_001398"
     CDS             complement(7748..8971)
                     /locus_tag="VQU19_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HET2480635.1"
                     /translation="MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNI
                     IKELSEQSLIYETGDEFSEFSGSGRRRKTISITDNIPYVVGGIEINVLGIFLSLCDLQ
                     GKTLFETEILNEDYPISEINSTITNMIKTAIEYVPLETKLLGFGLSIPGHYNKDSGSI
                     ITNNPIWESFNLLNVIKRFNFPFIVKNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIY
                     TSFFTKEKIGASKNPYIGEIGHTIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFK
                     NSQLTVLKSLVKTEKDIHLDTLLTAYNLGDSALRQQIDKGVNLLATSIANLLLINPAD
                     KIYINSQLLNYQPFTHEVRDKIQDQLHFVPFTRNIEIEILPYNKHRGSIGACALAIVA
                     FFIEHSNVLQDIISP"
     gene            9139..10461
                     /locus_tag="VQU19_001399"
     CDS             9139..10461
                     /locus_tag="VQU19_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET2480636.1"
                     /translation="MNNILAFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLILVGSL
                     FLILISWPQEDFTNWLNSVGLLSILTTMNQSTVAIISLVACFGIAYRLSEGYGTDGPS
                     AGIIALSSFVLMAPRFSSMVYDKNGEQVKQLFGGAIPFSSLNASSLFMAITIGLVTAE
                     IYRMFIQRGITIKMPSGVPDVVSKSFSALLPGFTTFVLWALVLKGLEAAGVAGGLNGL
                     LGAIVGTPLKLIAGTLPGMILCVIVNSFFWFCGVNGGQVLNAFVDPVWLQFTTENQEA
                     VAAGQTLQHIITLPFKDLFVFIGGGGATIGLAICLFLFSKSRANKTLGKLAIIPSIFN
                     INTAILFTFPTVLNPIMLIPFIATPTINALITYVSMAVGLVPYTTGVILPWTMPPIIG
                     GFLATGASWRGALLQVVLILVSVAIYYPFFKIADKRNLEKEKATVGGK"
     gene            10463..12349
                     /locus_tag="VQU19_001400"
     CDS             10463..12349
                     /locus_tag="VQU19_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HET2480637.1"
                     /translation="MVIRVFDQQKNTYSSFALEELSYYINRVFKTDIELVEEKEADIF
                     VGLVNKEDRKDHVLISLDKGKGRIESNTIVGLLIGIYRMFHEFGVVYTRPGRGHDFVP
                     ELRFEDFLDKELSIDETASYYHRGVCIEGADSFENILDFIDWLPKIGMNSFFIQFENP
                     YSFLKRWYEHEFNPYLNKEKFSNELVQELSDRLDKELQKRGLIHHRVGHGWTGEVLGY
                     SSKFGWESGLSISEEKKPYVAEINGKRELFNTAPILTSLDFSNPDVADKMVEIIKDYA
                     KKRPDVNYLHVWLSDARNNICECENCRQELVSDQYIRILNQLDRALTSEGLDTKICFL
                     LYHELLWAPQKEKLDNPERFTMMFAPITRTFEMSYADVDFDNSIPTPKPYLRNKIILP
                     NSLEENLSYLFEWQKTFKGDSFVYDYPLGRAHYGDLGYMKISQTIYRDVSYLSNLHLN
                     GYISCQELRAGFPHNFPNYVMGEMLWKKTRSYEELIEEYFSALYGSNWQSVVEYLEKL
                     SSYSSCDYFNAIGSRQNDVLANHYYIAYNLADNFLPIIEENISKLLNSQKDEWKQLSY
                     HREYVVKMAKALYLQATGKTRQAQDEWRNVLNYIRGHELLFQSNLDVYRVIEVAKNYA
                     GFHL"
     gene            12517..12861
                     /locus_tag="VQU19_001401"
     CDS             12517..12861
                     /locus_tag="VQU19_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET2480638.1"
                     /translation="MKSKEEINMLGFTIVAYAGDARSDLMDALAFARDGYFEQARELV
                     ESANDSIVSAHREQTNLLAEEASGDNFEVSFIMIHGQDTLMTTMLLYDQVKFFIDEYE
                     RIRKIEEHIGLQ"
     gene            12871..14283
                     /gene="lacG"
                     /locus_tag="VQU19_001402"
     CDS             12871..14283
                     /gene="lacG"
                     /locus_tag="VQU19_001402"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HET2480639.1"
                     /translation="MENLQVKALPKEFLLGAATAAYQVEGATRVDGKGTNMWDVYLQE
                     NSPFLPDPASDFYYRYEEDITLAAEHGLQALRLSISWVRIFPDIDGEPNILAVRYYHR
                     VFQSCLKHNVIPFVSLHHFDSPQKMLETGDWLNRENIDRFIRYARFCFQEFTEVKHWF
                     TINELMSLAAGQYIGGQFPPNHHFQLSEAIQANHNMLLAHALAVLEFHQLGIEGEIGC
                     IHALKPGYPIDGQKENILAAKRYDVYNNKFLLDGTFLGYYSEDTLFHLNQILEANNSS
                     FIIEDGDLEIMKRAAALNTMFGMNYYRSEFIREYKGENRQEFNSTGIKGQSSFKLNAL
                     GEFVKKPGIPTTDWDWNIYPQGLFDMLLRIKEEYPQHPVIYLTENGTALKEVKPEGEN
                     DIIDDSKRIRYIEQHLHKVLEARDRGVNIQGYFIWSLQDQFSWANGYNKRYGLFFVDY
                     ETQKRYIKKSALWVKGLKRN"
     gene            14353..16032
                     /locus_tag="VQU19_001403"
     CDS             14353..16032
                     /locus_tag="VQU19_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HET2480640.1"
                     /translation="MDKLVAAIEKQQGKFEKISTNNYMIAIKDGFIATMPLIMFSSFL
                     MIIIMIPKNFGVELPSPAIAWMRKVYMLTMGVLGIIVSGTVAKSLAGNVNRKMPPGKV
                     INDTSAMLAAICGYLVLTVTLVVDEKTGSTSLSTNYLGSQGLITSFVSAFITVNVYRF
                     CIKRDITIHLPKEVPGAISQAFRDIFPFSFVLLISGLLDIVSRFSLDVPFAQVFQQLL
                     TPIFKGAESYPAMMLIWFMCALLWFVGIHGPSIVLPAVTALQLSNMEENAQLLANGQF
                     PYHSLTPNFGNYIAAIGGTGATFVVPFILIFFMRSKQLKSVGKATITPVLFAVNEPLL
                     FGMPVILNPYLFVPFLMTPPVNVFLGKVFIDFFGMNGFYIQLPWAFPGPLGLLIGTNF
                     QLISFVFLSLMLVVDILIYLPFCRAYDRQLLVKEDIASSNDIILEEDTSEIMPGEIDV
                     IKSKELKVLVLCAGSGTSAQLANAINEGAQLAEVRVIANSGAYGAHYDIMGVYDLIIL
                     APQVRSYYREMKVDAERLDIQIVATRGMEYIHLTKSPSKALQFVLEHYQAV"
     gene            complement(16158..17597)
                     /locus_tag="VQU19_001404"
     CDS             complement(16158..17597)
                     /locus_tag="VQU19_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HET2480641.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSLIDAF
                     FEISSGFTTTGASILNDVSVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRIKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNKTVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(17601..18950)
                     /gene="trkA"
                     /locus_tag="VQU19_001405"
     CDS             complement(17601..18950)
                     /gene="trkA"
                     /locus_tag="VQU19_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HET2480642.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            19138..19986
                     /locus_tag="VQU19_001406"
     CDS             19138..19986
                     /locus_tag="VQU19_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HET2480643.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            20001..20549
                     /locus_tag="VQU19_001407"
     CDS             20001..20549
                     /locus_tag="VQU19_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HET2480644.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLVGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
BASE COUNT         6251 a         3505 c         4219 g         6650 t
ORIGIN      
        1 tgtcgaagag acagatctaa gagttcaaaa ccagctttat tatttgaaaa agtgagtggt
       61 ttaagaacag tttttcctgg aacattcaag gctgtaacat cgtgtttatt tttagcgata
      121 tcaatgccca cataaagcat gggagtacct ccagatatag tatttcaagt ctacttggtt
      181 atccacgaat tttttgcctt gttaccttag acgagatcaa acgtctatgc gttatcaaac
      241 tcattaccaa ttgaaacaaa agctgtggtt agagcctttc ggaaatcgtc aagcgattgg
      301 aggaaatgaa ctaatccaca gtggcttatt ccaagtatac cacttgggct ttggcagtag
      361 ctaactgcgc taattataat atagggagta atctatgtat cttattgaaa ttttaaaatc
      421 tatcttcttc gggattgttg aaggaattac ggaatggttg ccgatttcca gtacaggtca
      481 cttgatttta gcagaggaat tcatccaata ccaaaatcaa aatgaagcct ttatgtccat
      541 gtttaatgtc gtgattcagc ttggtgctat tttagcagtt atggtgattt attttaacaa
      601 gctcaatcct tttaaaccga ctaaggacaa acaggaagtt cgtaagactt ggagactatg
      661 gttgaaggtc ttgattgcta ctttaccttt acttggtgtc tttaaatttg atgattggtt
      721 tgatacccac ttccataaca tggtttcagt tgctctcatg ttgattatct acggggttgc
      781 cttcatctat ttggaaaagc gcaataaagc gcgtgctatc gagccaagtg taacagagtt
      841 ggacaagctt ccttatacga ccgctttcta tatcggactc ttccaagttc ttgctctttt
      901 accagggact agccgttcag gtgcaacgat tgtcggtggt ttgttaaatg gaaccagtcg
      961 ttcagttgtg acagaattta ccttctatct tgggattcct gttatgtttg gagctagtgc
     1021 cttaaagatt ttcaaatttg tgaaagccgg agaactcttg agctttgggc aattgttttt
     1081 gctcttggtc gcgatgggag tagcttttgc ggtcagcatg gtggctattc gcttcttgac
     1141 cagctatgtg aaaaaacacg acttcaccct ttttggtaaa taccgtatcg tgcttggtag
     1201 tgttttgcta ctttacagtt ttgtccgttt atttgtataa gaaaaacctt gaaggggcaa
     1261 ctcttcaagg ttttatactc ttcgaaaatc tcttcaaacc gcgtcagctt tatctgcaac
     1321 ctcaaaacag tgttttgagc agcctgcggc tagcctccta gtttgctctt tgattttcat
     1381 tgagctttaa aatccagtca tggtaatccc caataggcgg acacctcttt ctttcttgct
     1441 taattcttca tagagttgca gggctatttg gcttatctga ctagcatctt gtgttttttg
     1501 agcaagactt tttcgtttgg taagagttga aaagtcctcg tagcggattt tcaaaatgac
     1561 aatttttcca gctttttctt gttgatgtag attgagagcg actttttctg atagaagagt
     1621 cagctctttt ttgatatctt cctcagcaag gagaatcttc ccgtaggttt tctccttgcc
     1681 gattgattta cggatgcgat tggatttgac tggagagttg tgaatgccac gagcctttcg
     1741 atacagatca tagcctagtc taccaaaacg gtctattagg gttacctcag gaacttcaag
     1801 taaatcagca ccagtaaaaa cgcccatttg atgaagacgt tctactgtct tttttcctac
     1861 tccatgaaat ttggaaatat ccatttgttt gagaaaatcc tcagcctgtt caggtagaat
     1921 cactgtcaaa ccatgtggtt tttgataatc actcgccatt ttagctaaga atttgttgta
     1981 agaaacgcct gcggaagcag ttagatggag ttcttgccag atatcttttt gaatgaggcg
     2041 agcaattttg accgctgact tgataccgag tttattttct gtcacatcca aataggcttc
     2101 gtcaatgctc atgggttcaa tcaaatctgt atagcgctta aaaatagctc gaatctggag
     2161 tcccacagac ttgtatttct cataattccc tgagataaag acagcctggg gacaacgttc
     2221 ataagcttcc ttggaactca tggcagaatg gacaccaaaa gctcttgcct cataactaca
     2281 ggtagaaacg actccccgtc cacctgtttg ccgagggtcg cttccaataa tgacaggttt
     2341 tcctctgagt ttaggattat ccctgatttc cactgcagca aaaaaggcat ccatgtcaat
     2401 atggatgatt tttcttgaca aatcatttaa caaaggaaaa atcaacatgc ctagcacctt
     2461 tttatactct tcgaaaatct cttcaaacca cgtcagctct atctgcaacc tcaaaacagt
     2521 gttttgagca atctgcggct agcttcctag tttgcttttc gatttccatt gagtgttact
     2581 gcttattttc ttttattata cccttttttc tgaaaaaaag aaaaaaggac tttatttttt
     2641 caaaaatata atacagtttg aaataaaata tagactgttt tagaaaagaa agtgtaaaaa
     2701 tagggaattt tcacttgttg aaatcggtta ctatatggta tacttgtctt atgaatgtaa
     2761 cagatgactg ttactagaaa aaagaggaca ttaatatggt tgttaagaca gttgttgaag
     2821 cacaagatat ttttgacaaa gcttgggaag gcttcaaagg cgtagattgg aaagaaaaag
     2881 caagtgtatc acgatttgta caagctaact acacacctta tgatggagac gaaagcttcc
     2941 ttgcaggacc aacagagcgt tcacttcaca tcaagaaaat tgtagaagaa actaaagcac
     3001 actacgaaga aactcgtttc ccaatggaca ctcgtccaac atctatcgct gatatccctg
     3061 ctggatttat cgacaaagaa aatgaagtta tcttcggtat ccaaaacgat gaactcttca
     3121 aattgaactt catgccaaaa ggtggtatcc gtatggctga aactactttg aaagaaaatg
     3181 gatacgaacc agacccagct gttcacgaaa tcttcactaa atatgtaaca acagttaacg
     3241 acggtatttt ccgtgcctac acttcaaata ttcgtcgcgc tcgtcacgca cacactgtaa
     3301 ctggtcttcc agatgcatac tcacgcggac gtatcatcgg tgtttacgca cgtcttgctc
     3361 tttacggtgc agactacttg atgcaagaaa aagtaaatga ctggaatgca atcaaagaaa
     3421 tcgatgaaga aacaatccgt cttcgtgaag aagtaaacct tcaataccaa gcattgcaac
     3481 aagttgttcg cctgggtgac ctttacgggg ttgatgttcg caaaccagcg atgaacgtga
     3541 aagaagcaat ccaatgggtt aacattgctt tcatggctgt ctgccgtgtg attaacggtg
     3601 ctgctacatc tctaggtcgt gtaccaatcg tattggacat ctttgcagaa cgtgaccttg
     3661 ctcgtggtac atttactgaa tcagaaatcc aagaattcgt tgatgatttc gttatgaaac
     3721 ttcgtacagt taaatttgct cgtacaaaag cttatgacca attgtactca ggtgacccaa
     3781 cctttatcac aacttctatg gctggtatgg gtaacgacgg tcgtcaccgt gttactaaga
     3841 tggactaccg tttcttgaac actcttgaca acatcggtaa ctcaccagaa ccaaacttga
     3901 cagttctttg gactgacaaa ttgccataca acttccgtcg ctactgtatg cacatgagcc
     3961 acaaacactc ttctatccaa tacgaaggtg taacaacaat ggctaaagac ggatatggtg
     4021 aaatgagctg tatctcatgc tgtgtgtctc cacttgatcc agaaaatgaa gaacaacgcc
     4081 acaacatcca gtacttcggt gctcgtgtaa acgttcttaa agcccttctt actggtttga
     4141 atggtggtta cgacgatgtt cacaaagact acaaagtatt tgatatcgaa ccaatccgtg
     4201 acgaagttct tgaatttgaa tcagttaaag cgaactttga aaaatctctt gactggttga
     4261 ctgacactta cgtagatgcc ttgaacatca tccactacat gactgatagg tacaactacg
     4321 aagctgttca aatggccttc ttgccaacta aacaacgtgc caacatggga ttcggtatct
     4381 gtggatttgc taacactgtt gatacattgt cagctatcaa atacgctaca gttaaaccaa
     4441 tccgtgacga agatggctac atctacgatt acgaaacaat cggtgactac ccacgctggg
     4501 gtgaagatga cccacgttca aacgaattgg cagaatggtt gatcgaagct tacacaactc
     4561 gtctacgtag ccacaaacta tacaaagacg cagaagctac agtatcactt ttgacaatca
     4621 catctaacgt tgcttactct aaacaaactg gtaactcacc agttcacaaa ggtgtatacc
     4681 tcaacgaaga tggttctgtg aacttgtcta aacttgaatt cttctcacca ggtgctaacc
     4741 catctaacaa agctaaaggt ggttggttgc aaaacttgaa ctcactttct agccttgact
     4801 ttagttatgc agctgacggt atctcattga ctacacaagt atcacctcgc gctcttggta
     4861 agactcgtga tgaacaagtt gataacttgg taacaatcct tgatggttac ttcgaaaacg
     4921 gtggacaaca cgttaacttg aacgttatgg acttgaacga tgtttacgaa aaaatcatgt
     4981 caggcgaaga cgttatcgta cgtatctctg gatactgtgt aaacactaaa tacctcactc
     5041 cagaacaaaa aactgaattg acacaacgtg tcttccacga agttctttca atggatgacg
     5101 ccttggatgc attgagctaa tcaagttctt gaataataaa aaggaaccct cggtcaaacg
     5161 actgagggtt ttgtgcttgg gatagtatga gcaattcctt cggcgcaata tgcaatgttt
     5221 ttgggaagga atagtggacc gaatctgaaa tataatagat tgaaactaga atagtacacc
     5281 tttacttcta aaacattctt agaaatcgat ttgactgtcc tgatcgattt gtcctattct
     5341 tatttcattt tactatagtc cgctgaaacg gctcaaacag tgctagaaat tgactggaat
     5401 tctctaagtg atttgttccg attttatttc atttcatcat aaaaataaga tgactggcta
     5461 attgacaatc atcttgtttg atactgttaa taaaattcgc gaagtttatc ttgattttct
     5521 ttaaaaaatt tttctaacca atccatacca taagcataac taaaaccttc taatagaaca
     5581 gagaggtcaa tagtatcaaa tcccatgtct tttaaatatt taaaggtatc gaatggtgaa
     5641 tgaaagtttt tgtatttaat aattgcacca atatcttgca aatcctgctc tctgatactc
     5701 atcatcttca ttcctaacac atactcaata gggactacta aaacggtcag attctcaaat
     5761 gagtacaagg attcgcataa acttaaggga ggttgtttgt tcatatttgc tttgcaacat
     5821 gattgttgag ccataactct tcgtggatgt taagattaaa ctgttttcct acacgagcaa
     5881 taatttcatt gattttctga ttttggtcat aaaaagcatc aacatcttgt gtggcacgta
     5941 aaccatgata ttctaagaca taaccataat tgttaaagtc agattttcct gaattaattt
     6001 cttatttagg gcttggaaga ccggtttcat tttatccatg tttgtatttc tccatcaatt
     6061 tttgaacatt ggttaactta gcaggtttat ttaatgaaat cacatattta tgagttggag
     6121 tatgctcttg aaaggcatac ttcaagctaa ttttttgaaa acgggttagt tctttggagt
     6181 ctagcaactt ttctacatct tggtttgtta aataagaata gtcttcaaaa ataacttttc
     6241 gcaaatagcg aaaccaatgg cttgcgttga attgtgattg tttggatgcc tgtatcatat
     6301 aatcgtacca atccattgtc ttcctcctat aaaatttagt ttatattatt gtagtttata
     6361 ttcaaaaatg tagtttttct taattagctc gtatctatag gatgatactg aaaatcttct
     6421 tgttgcttta aatcacaatc gaaaaattct gtttttcatc ttagaaaaga atgtttagaa
     6481 atgtaaaatg aacctttttt cttatccgaa aaccttacta aagtatataa tttaggcagt
     6541 caattctgta tgataatgtt tgtactatcg tcgagttttt gcttgattgc ctaacgagat
     6601 aaattttaga agagttttcg gtgtgatttg acaagtttct gactggaagg atagttacac
     6661 tagtattgtt tattaaaatg agcagataga gaaaatttgg aatctatttg cttattatca
     6721 atcgtttttt tagcttattt gtcttagatt ggtatagaac tgagctatgg attaatcttc
     6781 ttctatctta tcctgttcct aaatatgttg gtagaaaaat gaagcagttg ttacgagtgt
     6841 ctgtattggg aaaaattttg tctatagaat tctttaaatg atatgaaggc taggaatgcc
     6901 aaaacactga catatttcgt ttaaagtcta tccagtctct tcaattgtat ttgtagaaat
     6961 gctatcagta atatattcgc gaacactatg atttacaaca gtgtggtcgt acatctttgt
     7021 aactttatta tacaacaacc atttacaggt gtaaagttga gcagtgtctt tagtaaattt
     7081 agggacttgt tttgtcatag ttttgatacc tgtattcgtt gtttcatgag catttgacgt
     7141 ttcttttcat gtaggcattt caacaattag aatgatattt ttccgaggat gaacttatat
     7201 attgtgactt tttagagtta tgatgcctct tgatttgact accgctatca atttcatcca
     7261 cttttacagt ttcatggttt tatgaaccga aacatctagg tacaggtttt agcatcaatt
     7321 gattgttttt gagccatatg aagttgaaac gtggagatgc ttttcttgtg ataacgccct
     7381 attcaaagag gaataaccgt ttttggagag agttcagtac tatgtggcgc taaatactat
     7441 atgtaaaaca tatattaaac aagatttaac taaggagaat tgtaaaaaca aaaatgagaa
     7501 tttcatataa agtttattct aggagtatgt atcttgaata aaaatcgtta tttaagttca
     7561 gggttatgat gaatgttttt ataataataa aatgcagcta gaagaaaagt tattttaata
     7621 taaatcactc aacatagaga gaaggcggtt tcctatatgg aagtcgtctt gttttcatat
     7681 tgtctaaata cgagatatct actacaggtt atagttgatt taaacaggtc tatagatttc
     7741 taatatatta aggtgaaata atatcttgta atacattgct atgttctatg aaaaaagcga
     7801 cgatagctaa tgcacaagct cctatacttc cacgatgttt gttgtaaggt aaaatttcaa
     7861 tttctatatt acgagtaaag ggaacgaagt ggagctggtc ttggatttta tccctgactt
     7921 catgagtgaa aggttgataa ttaagcaatt gactgttgat atagatttta tcagcaggat
     7981 tgatgaggag gagatttgca atagaagtgg ctaataaatt gactccttta tcaatttgtt
     8041 gacgtaaagc ggagtcgcct aaattataag ccgttaaaag ggtgtctaaa tgaatgtctt
     8101 tttcagtctt tacaaggctt tttagtacag ttagttggga atttttaaat aataattggg
     8161 cgtgtttgat taaccaagca tccgaaatat atgtttgtaa acaacctttt tttccgcatt
     8221 cacaatattg cccattcaat tcgacaatgg tgtgtccaat ttctccgata taaggatttt
     8281 tagaggctcc tattttttct tttgtgaaaa aggaagtgta aatacctaat ccagcgtgta
     8341 ggaaaataaa gttatcgggg gtattgtgtg gattaaaaag gtattgtcct atagccatac
     8401 aatcgatatt attttttaca ataaaaggaa aattgaatct tttaattaca tttaataaat
     8461 taaaagattc ccatatgggg ttgtttgtaa tgatacttcc ggagtctttg ttataatgtc
     8521 caggtattga taagccaaat ccaagtaatt ttgtttccaa agggacgtac tctatagctg
     8581 tttttatcat attggtaatg gtggaattga tttctgaaat aggataatct tcattcaaaa
     8641 tttctgtctc gaaaagagtt ttcccttgta agtcacatag actgagaaag atacctagga
     8701 cgtttatttc aatacctcca acaacatacg gaatattatc tgtgatagaa atagtttttc
     8761 tacgtcttcc agatccggaa aactcgctaa attcatcacc agtttcgtat atgagggact
     8821 gttcgcttag ctcttttatg atgttagtcg ttgttgctgg agtaagtcct gtttcattaa
     8881 caatatctgt acgggatgtt gctggatttc gatatagaaa ctccagtata gtggctctat
     8941 tttgtaaaaa ggctgattgt tttgtaatca tttgtttcct cctttggttt attttatatt
     9001 aaacataaga aaaaatcaat taaaattatt attttataca aagaaaaaaa tattgtaaaa
     9061 acaacaaaaa atatattgac aacgctttct gttagtggta tatttaattt ataaaaaata
     9121 aaaaaaggag ttccggtgat gaacaatatt ttagcgtttt tagaaacaaa agtcgctccg
     9181 tttggtgaaa aagttggcaa ccaacggcat ttgaaagcta ttcgtgaagg atttatgatg
     9241 gcaatgcctt tgattttagt cggatcttta tttcttattc taatcagttg gcctcaagag
     9301 gattttacaa attggctgaa tagtgttgga ttgctaagta tcttgacaac tatgaatcag
     9361 tcaacagtag cgattatctc cttggtcgct tgtttcggta ttgcctacag gttgtcggaa
     9421 ggatatggta cagatggtcc gtcggcaggg atcatagcct tatccagttt tgtattgatg
     9481 gcacctcgtt tttcgagtat ggtttatgat aaaaatgggg agcaggtcaa gcagttattt
     9541 ggcggcgcaa taccattttc tagcctgaat gcatcttctt tgtttatggc gattactatt
     9601 ggattggtta cagcagagat ttatcgtatg tttatccagc gcggaattac gataaaaatg
     9661 ccaagtggtg tcccagatgt ggtaagtaaa tcattttcag ctcttttacc tggctttact
     9721 acttttgttt tgtgggctct ggtcttaaaa ggtcttgaag cggcaggagt tgcaggaggt
     9781 ctcaacggac tcctaggtgc aattgttgga acaccgctta agttaattgc aggaacgctt
     9841 ccaggtatga ttctatgtgt tattgtaaac tcattctttt ggttctgtgg agttaatggg
     9901 ggacaagttt taaatgcttt tgtagatcca gtttggttac aatttactac agaaaaccaa
     9961 gaagctgtgg ctgcaggaca aacactccaa cacattatta cattaccgtt taaagattta
    10021 tttgtattta ttggtggcgg tggagcgact attggtcttg cgatttgtct cttcctattt
    10081 agtaagagtc gtgcgaataa aacattaggt aagctagcta ttataccgtc tatttttaat
    10141 atcaatacag ctattctatt tacgtttcca acagttttaa atccgattat gctgattccg
    10201 tttattgcta ctcctacaat caatgcctta attacctatg tatcaatggc tgtaggatta
    10261 gtaccctaca caacaggtgt aatccttccg tggacaatgc caccgatcat aggaggcttc
    10321 cttgcgacag gagctagttg gcgaggagct ctattacaag ttgttttgat tttggtttct
    10381 gtagcaattt attatccatt cttcaaaatt gcagataaac gcaatcttga aaaagaaaaa
    10441 gctactgttg gagggaaata agatggttat cagagtattt gatcagcaga aaaatactta
    10501 ttctagcttt gccttagagg aattaagtta ctatataaat cgggtcttta agactgacat
    10561 agaacttgtc gaggagaagg aagcggatat ttttgtagga ttagtcaata aagaggatag
    10621 aaaagaccat gttcttatct cattagacaa gggtaagggg agaattgagt ctaatacaat
    10681 tgtaggtttg cttattggaa tttaccgaat gtttcatgaa tttggggttg tgtatactag
    10741 accagggcgc ggacatgact ttgttccaga gttacgattt gaagattttt tagataaaga
    10801 gctatctata gatgaaacag ccagttacta tcatagggga gtatgtatag agggagcaga
    10861 ttcatttgaa aatatactag atttcattga ttggctacct aagattggga tgaacagttt
    10921 tttcattcag tttgaaaatc cctattcttt tttgaaacgt tggtatgaac atgagtttaa
    10981 tccataccta aataaagaaa aattctcaaa tgaattagta caagaattga gtgataggtt
    11041 ggataaagaa ttgcaaaaaa gaggtcttat tcatcatcgt gttggtcatg gatggacagg
    11101 tgaggtttta ggttactctt caaaatttgg ctgggaatca ggtcttagta tttcagagga
    11161 gaagaaaccc tatgtcgctg aaataaacgg gaaacgagaa ttatttaata cggctccgat
    11221 tttaaccagt ctggattttt caaatccaga tgtggcggat aagatggtag aaattatcaa
    11281 ggattatgcc aagaaaagac ctgatgttaa ctacttacat gtatggttgt cggatgctcg
    11341 taataatatt tgtgaatgcg aaaactgtag acaagaattg gtttcggatc agtatattcg
    11401 tattctcaat caattggata gggctttaac gagtgaggga ttagatacaa agatttgttt
    11461 tctgctttac catgagttgt tatgggcgcc tcagaaagaa aaattagata atcctgaacg
    11521 ctttaccatg atgtttgcac cgattacaag aacatttgaa atgagttatg cagatgtaga
    11581 ttttgacaat tccataccta cgcctaaacc ttatctgcgt aataaaatta tacttccgaa
    11641 ttctcttgag gaaaatttat cttatctttt tgagtggcaa aaaacattta aaggagatag
    11701 tttcgtatat gactatcctt tagggcgtgc tcattatggc gatttaggct atatgaaaat
    11761 tagtcaaacc atttacagag atgtatctta tctttctaac ctacatttga acggttacat
    11821 ttcgtgtcaa gaattacgtg ccggattccc tcataatttt cctaattatg ttatggggga
    11881 aatgctctgg aagaagacaa gaagttatga agaattgatt gaagaatact tttctgcttt
    11941 gtatgggtca aattggcagt ctgttgttga atatttagaa aaattatcca gttattcctc
    12001 atgtgattat tttaatgcaa ttggcagtcg tcaaaatgat gttttagcga atcattatta
    12061 tatagcttac aatctagctg ataatttttt gccaattatt gaggaaaata tttctaagtt
    12121 attaaatagt caaaaggatg aatggaaaca gctcagttat catcgtgaat atgttgttaa
    12181 gatggcgaag gctttatatc ttcaagcaac cggaaaaaca aggcaagctc aagatgaatg
    12241 gagaaatgtg ttgaattata tccgtgggca cgaattgcta tttcaatcta atttggatgt
    12301 ttatcgtgta attgaagtag caaaaaatta cgctggtttc cacttataaa tcataagtat
    12361 agaaaatgaa ccaaggtatt cagagaagat tgatcctaaa tattatgaaa tttaaggatt
    12421 tttaagatat ttagggtcga ctttctattt atatcgtagc gaagtcattt taataatgat
    12481 gtgtaaaaga tggatcaaga ttgaggagga agaaagatga aatcaaaaga agaaataaat
    12541 atgcttggtt ttacaattgt cgcttacgca ggagatgcaa ggtcagattt gatggatgct
    12601 ttggcgtttg cgagagatgg atattttgaa caggcaagag aattggttga gtctgcaaac
    12661 gactcaatag tgtctgccca tcgagaacag actaatttat tagcggagga ggcatctgga
    12721 gataattttg aagtgagttt tatcatgatt catggtcaag ataccttgat gacaacgatg
    12781 ctattgtatg atcaggtcaa gttttttatt gatgaatatg aacgaattcg aaagattgaa
    12841 gaacatattg gtttgcaatg aggattagtc atggaaaatt tacaggttaa agccttaccg
    12901 aaggagtttt tattaggagc tgctaccgct gcttatcaag tagagggtgc aactagggta
    12961 gatggcaaag gaacaaatat gtgggatgtt tatttgcaag aaaacagtcc gttcttacca
    13021 gatccagcta gtgattttta ttatcgttac gaagaggata taactttggc ggcagaacat
    13081 ggtttgcagg ctttgcgttt atctatttct tgggttcgta tatttcctga tatagatggg
    13141 gagcctaata tattagctgt tcgttattac catagagtct ttcagtcttg cttaaaacat
    13201 aatgtgattc cgtttgtttc tttacatcat tttgattcgc ctcagaaaat gttagaaaca
    13261 ggggattggt tgaatagaga gaatattgat cgtttcatac gatatgctcg cttttgtttc
    13321 caagaattta cagaagtcaa gcattggttt acaatcaatg aactgatgtc tcttgctgca
    13381 ggtcaatata taggaggtca gtttcctcca aatcatcatt ttcaattatc tgaagcaatt
    13441 caagcgaatc ataatatgtt gttggcgcat gctcttgcag tcctcgaatt tcatcaatta
    13501 ggaattgagg gagagatagg ttgtattcat gctttaaagc caggctatcc tattgatggg
    13561 caaaaagaaa atattttggc agctaaacgg tatgatgttt ataataataa atttctatta
    13621 gatggaactt ttttgggcta ctacagtgag gacacgcttt ttcacttgaa tcaaatattg
    13681 gaagctaata attctagctt tattattgaa gatggtgatt tagaaattat gaagagagct
    13741 gcagctctta atacgatgtt tgggatgaat tattatcgtt cagaatttat tcgtgaatac
    13801 aaaggtgaaa atagacaaga atttaattca acaggaataa aaggacagtc ttcttttaaa
    13861 ttaaatgctc taggtgaatt tgtaaaaaaa cctggtattc cgacaacaga ttgggattgg
    13921 aatatttatc ctcaagggtt atttgatatg ttgcttcgta tcaaagaaga atatcctcaa
    13981 catccggtca tttatttaac tgaaaatggt acagccctta aagaagttaa gccagagggc
    14041 gagaatgata ttattgatga cagtaagaga atccgttata ttgagcaaca tttacacaaa
    14101 gttttagagg ctcgagatag aggagtcaat attcaaggct attttatatg gtctttgcaa
    14161 gatcaatttt cttgggcgaa tggctacaat aagcgatatg gtcttttctt tgttgattat
    14221 gaaacacaga agagatatat taagaaaagt gctctttggg taaaagggct aaaacggaat
    14281 taaggttagc gatttgactg atgtttaata tattttaact atgagcttaa attttttaca
    14341 ggaggagttt ttatggataa gttagtcgct gccattgaaa agcaacaagg gaaatttgaa
    14401 aaaatttcta ctaataatta tatgatagct attaaagatg gatttattgc tactatgcct
    14461 ttaattatgt tttcaagctt tttgatgatt attattatga ttcctaaaaa tttcggagta
    14521 gagttaccga gtccagctat tgcctggatg aggaaagtgt atatgctaac catgggagtt
    14581 ttgggtatta ttgtttcagg gacagttgca aagtcattgg ctggaaatgt taatagaaaa
    14641 atgcctcctg gaaaggtaat aaatgatact tctgcaatgt tggcggccat atgtggctat
    14701 cttgtattaa ctgtaacgct tgtagttgat gagaaaacgg gatctacaag tttgtcgaca
    14761 aactatttag gatctcaagg attgataact tcgtttgtca gtgcctttat tactgtaaat
    14821 gtttaccgat tctgtattaa gcgagacatt actattcatt tacctaagga agttcctggg
    14881 gctatatcac aagcttttag agatattttt cctttttctt ttgttttact tattagtggt
    14941 ttgttagata ttgtatctcg gtttagttta gatgttcctt ttgcccaagt atttcaacaa
    15001 ctattgactc ctatttttaa gggggcagaa tcatatcctg ctatgatgtt gatttggttt
    15061 atgtgtgctt tgctttggtt tgttggaatt catggaccat ctattgtctt acctgctgtt
    15121 acagctttac aactgagcaa tatggaagag aatgctcaac ttcttgcaaa tgggcagttc
    15181 ccttatcatt ctttaacacc taatttcggg aattatatcg ctgctattgg aggaacgggg
    15241 gctacctttg ttgtaccatt tattttgatt ttctttatgc ggtctaaaca attaaaatcg
    15301 gtaggtaaag ctacaattac tcctgtttta tttgcggtaa atgaacctct tctatttggt
    15361 atgcctgtta ttttgaatcc ctatcttttt gtcccttttt tgatgactcc accagtgaat
    15421 gtatttctag gaaaggtatt tattgatttc tttggaatga atggatttta tatccagtta
    15481 ccttgggcct ttcctggtcc cttgggattg ttaattggaa cgaattttca acttatctcc
    15541 tttgtatttt tatctttgat gttagttgtc gacatattga tttatttgcc attctgtaga
    15601 gcgtatgata gacagttact ggtgaaagaa gatattgcaa gctcaaatga tattatttta
    15661 gaggaggata caagtgaaat aatgcctggt gagatagatg taataaaaag taaggagttg
    15721 aaagtactgg ttctttgtgc agggtctgga acaagtgcgc aattagccaa tgcaattaac
    15781 gagggcgctc aattagcaga agttagagtg attgcgaatt caggagcgta cggagctcat
    15841 tatgatatta tgggtgttta tgatttaatt attctggccc cacaagttcg gagttattat
    15901 agagagatga aggtggatgc agaaagatta gatattcaga tagttgctac cagaggaatg
    15961 gaatatattc atttaacaaa gagtccaagt aaagccttac aatttgtatt ggagcattac
    16021 caagctgtgt agtaagtttt tccatctttt atttgagtaa agattttgct tacagatagg
    16081 cttggattta aaaacgttcc ccctttttta atataagaat ccctctttca caattgtaaa
    16141 aagagggatt ttgtatttta tctcttagac caagttctct tcataaagag aaggaggatt
    16201 gggtaaatct ccaagcgccc tgcaatcatt gcaaaggata ggagaatttt tgagatggga
    16261 ctaaagattg agaaactaga agtggttcct agaataggcc cgatattatt gaaacagcta
    16321 aagacagcgc tggtcacgac cagaaaatca ttgctatcta ggctgacaat aaagataagc
    16381 gctagcaaaa tcatagcata gatgacaaag tacttgagaa tcttatgctg ggtatctttg
    16441 tcaatcaccg ttttattaac atggagggtc aaaacacggt ggggcgatag gattgacaaa
    16501 atttggtttt tggcaatttt tgaaaggatg aggcctcgaa taatcttgag tccacctgca
    16561 gttgatccag cagagccacc gattgccatg aggaaaagga ggataaactg ggagaagagg
    16621 ggccagttgg taatatctcc atatccaaaa ccagttgttg taatgatgtt ggaaacctgg
    16681 aagaaggtca tttcaaagct ctttgaaaac cctgggtaga ggtagagggt gttgaggcta
    16741 atcaagcctg tagaaaccag tacaatgacc aagtaagccc taagctcttc atctccaaag
    16801 aaggccttga tgcgacggag catgaggtag tagtagaggt tgaaatttac tccaaaaacc
    16861 agaactccga tactgaccag ataggtaatc agtgagctgc catagtgggc aattccgtcg
    16921 ttatagacgg taaagcctcc agttcccgct gtccccatag caatgacaaa actatcgtag
    16981 agaggcatac cagctagata atagatgatg acaaagaggg agaagagagc tagataaagg
    17041 agatagagaa tctgggcagt gttttttagt ttggatacaa ccttgccaaa aacaggacct
    17101 ggaacctcag ccttcatcac ctctaggtgg ctatttttgg cattgtccat aatagcaagt
    17161 gcaaaaacaa gcactcccat ccctccaatc aagtgggtaa aacttcgcca gaagaggagg
    17221 gaacgactga gaactgaaac gtcgttcaaa atacttgctc cagtagtcgt aaagccggaa
    17281 ctaatctcaa aaaaggcatc aataaggctg gggatttgcc cagaaaagac aaaggggaga
    17341 ccaccaaaga aagaccaaag gatccaacag agggcaacga tcaagactcc ctccttggca
    17401 taaatccgtt gattttttgg cttctgtaaa ctccctgaac cgcctaacaa tacgagaatc
    17461 cctatggtcg aaaagagggc tgtaaagact tggctcgatt cacggtaata gacagcgata
    17521 gccacaggaa ccaagaggag aacagcttca atcaaaagta actttgaaag gaggtaacga
    17581 atcatacttt tattcatttc ttacctcgca atcaagtcat aaatcttggt gatgtttggc
    17641 aacaaggttg ttactaggag cttgtctcca acttccaaca tatcctcccc agttgggaaa
    17701 atagtcttgc cctttcgaat aatggctgca ataagaaccc cttttttcaa tttcagttga
    17761 gaaagaggtt tggcagtcat tttattggct tccttgatat ggaattgcag ggtttcgatt
    17821 tggccattgg ctagatggtg catggcttga aggtctgaat actgggcatt aactcgacca
    17881 cgaataaagt gcataatcgt atctacagcg atgcttttag gtgtgatgat acttgaaaaa
    17941 tcaggcgcat tgataatctc gaggagactg gtacgattga ccttagtaat atttttctgt
    18001 acacctaccc tgtcaaggaa catagatgta atcagatttt cctcatcgac tcctgttaga
    18061 gtcgcaacgg catcatagtg ttgagcactt tcttccagca ggatatcttt tgcggttcca
    18121 tctccttgaa cgatgtagag atttgggaat ttctcgctaa agaagctggc gatttcagga
    18181 ttgatttcaa tgacttttgt atcgatacga ctatctttga gaataccaag tagataatag
    18241 gcaattctac ctgccccaac gatgagaagg ctcttcacgg cgcgtgattt aaaataatta
    18301 tggaagagta tcatatcgac acggttacca gtgacaaaga ttctatcttt atcctgtaca
    18361 gtcatgtcac cgcttggaat gataatttga tgatccctct ctatcgcaca gacaatgaca
    18421 ttaccaaatt ttttacgaaa atcagaaatg ggcatttggc aaagaccgct ggtggacttg
    18481 acgacaaatt ccatgaggct aacgcgtcca ccagcaaagc gttcgacaga cagggcgttg
    18541 gggaagtcaa tgatattcgc gatagcacgg gcagccaaga gctcaggatt aacgataaga
    18601 gaaaaaccga gaatattctt ttccttgaaa taagagttag aatattcagg gttccgcacc
    18661 cgaacgatag tttctttagc tcccattttc ttggctagaa ctgctgcaat catgttgact
    18721 tcatcgtgct cagtcagggc gataaagata tcacaatctt ggacgctggc ttgctcaaga
    18781 atggcaaaat cggccccgtt accaaggata ccaatgatat caaagcgact gacaatatga
    18841 ttgagaacag cttcgtcttg ctcaatcagc aaaacatcat gcttttctgc aaccaaggag
    18901 cgacagaggg caaaaccaac ttttccccct ccgacaagga taattttcat aataaaacct
    18961 actttttcat gatgtaacta tcataccctt tttcaagaaa aaatgcacct actagctaat
    19021 aacaagagct tttagtgaaa attcgctata agataaaact ataccctaac caattgaaat
    19081 agctattagc gactttctct gaaatatggt atgataaagg atatacaagg agataaaatg
    19141 aataataatt tactggtatt acaatcagac tttggtctgg ttgatggtgc ggtatcggct
    19201 atgattggag tggctttaga agagtctcca accttaaaaa tccatcactt gacgcacgat
    19261 atcacgcctt ataatatttt tgaggggagc tatcgtctct ttcagacggt ggattactgg
    19321 cctgagggaa cgacgtttgt atcggttgtc gatccaggtg tcggttcgaa acgtaagagt
    19381 gtagttgcca agactgcaaa aaatcaatac attgtcacgc cagataatgg gacgctttcc
    19441 tttatcaaga aacacgttgg cattgtagcc attcgtgaga tttctgaggt ggccaatagg
    19501 cgtcaaaaca cagagcattc ttataccttc cacggtcgtg atgtctatgc ctatactggt
    19561 gctaaactgg ccagtggtca cattactttt gaggaagtag ggccagagct cagtgtggaa
    19621 cagattgtag agcttccagt cgtagcgacc atcatagaag atcatctggt gaagggagcc
    19681 attgatattc tggatgtgcg tttcggttcg ctttggacct ctatcacacg ggaagaattt
    19741 tacaagttgg aaccagaatt tggtgatcgt tttgaagtga ccatctatca tgctgatatg
    19801 ctggtctatc aaaatcaggt tgtctatggc aaatcatttg cagatgtgag aattgggcaa
    19861 cccatccttt acatcaactc tctctatcgt ttaggtttgg ctatcaacca aggttccttt
    19921 gccaaggcct ataatgtagg tgtcggttca tcttggacca ttgaaataaa gaaaatagaa
    19981 ggataaaata ggagaatagt atggaaatca aatttacaat taaacaagtt gttgctgtcg
    20041 gaattggcgc tgccctcttt gtcgtcatcg ggatgatcaa cattccaacc cctgttccaa
    20101 atacaagcat ccagcttcag tatgcggtac aagcgctact ttctattatt tttggaccga
    20161 ttatcggttt gcttgttggg ttgattggtc atgcaatcaa ggactctctt gttggttatg
    20221 gtctatggtg gacttggatt atcgctagcg gactctttgg tttagttgtg ggacttttta
    20281 gaaagtacgt tcgcgtgatc aatggtgttt ttgactggaa agatattctt atttttaacc
    20341 tcattcaact acttgcaaat gcccttgttt ggggtgtctt ggcaccactt ggagatgttg
    20401 tgatttatca agaagcggca gaaaaagtat ttgcacaagg aattgttgcg ggaattgcca
    20461 atggtgtatc tgtagctatt gcaggaactc ttctcttact tgcctatgca ggaacccaaa
    20521 ctcgtgcagg aagtttgaaa aaggactaat actcaatgaa aatcaaagag caaactagga
    20581 agttagccgc aggttgctca aaacagtgtt ttgaaattgt ggata
//
LOCUS       DAVBCA010000041        20308 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.041, whole genome shotgun sequence.
ACCESSION   DAVBCA010000041 DAVBCA010000000
VERSION     DAVBCA010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20308)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20308)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20308
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.041"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..299)
                     /locus_tag="VQU19_001408"
     CDS             complement(<1..299)
                     /locus_tag="VQU19_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HET2480645.1"
                     /translation="MMYLDGGGVGCNWWNKRDNIAAAAVSGGMSVYQTYAIKKLIANR
                     GMMSRVVRSAITRYIGGVSMATITNALNIAATVAEVFSLGGAIAYGLDIVDGKFDG"
     gene            complement(279..347)
                     /locus_tag="VQU19_001409"
                     /pseudo
     CDS             complement(279..347)
                     /locus_tag="VQU19_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
     gene            complement(762..974)
                     /locus_tag="VQU19_001410"
     CDS             complement(762..974)
                     /locus_tag="VQU19_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000989850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480646.1"
                     /translation="MMVVLISVIVAFLYHKITEYVNNRKIDIVIFLSLLISHFIWNYY
                     FLPIEILIAISGANLLLSFLKKLQIK"
     gene            complement(993..1352)
                     /locus_tag="VQU19_001411"
     CDS             complement(993..1352)
                     /locus_tag="VQU19_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480647.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAIYIPRWAITGAITGAAYAAL
                     AAAGGGGLQLVLASYGLRSALVAGIVKGLGVLGIHIGNAFANTVIRSIASAGIGAGAD
                     WILPILLMAGMGDVIIN"
     gene            complement(1330..1668)
                     /locus_tag="VQU19_001412"
     CDS             complement(1330..1668)
                     /locus_tag="VQU19_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HET2480648.1"
                     /translation="MLKKYPCTMQHDQSDCAAAVVSTVLLSYKKELSIMKIREIIGTD
                     MYGTTVSGIVSGLNKLNFTVKAVRVALEDLTPKLTFPAILQVKNDLGQNHFVVLHSIK
                     EKINGTRITK"
     gene            2134..2997
                     /locus_tag="VQU19_001413"
     CDS             2134..2997
                     /locus_tag="VQU19_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2480649.1"
                     /translation="MRYDFGKVYKEIRESKGLTQEEVCGGVLSRTSLSKIESGKTTPK
                     YENMEFLLRQINMSFEEFEYICQLYQPSQRTEIMQTYLNMRSIIGTSDLVNLFQKCQD
                     YLKTHHDLPIEEIRDMLEVVIYLRQHGAGELSKHAEQVVKKLWKKIEKQDTWYESDLK
                     ILNTILFSFPIEYLHLITGKILQRLEVYKNYQHLYDLRMTILLNLSTLYLYNQDKNMC
                     KQICYTLLEDAKNKKSYDRLAICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKK
                     EVEIYYQAKER"
     gene            complement(3049..3621)
                     /locus_tag="VQU19_001414"
     CDS             complement(3049..3621)
                     /locus_tag="VQU19_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HET2480650.1"
                     /translation="MKSITKKIKATLAGVAALFAVFSPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVDQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNGDYSAE
                     NQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            3863..4534
                     /gene="sdaAB"
                     /locus_tag="VQU19_001415"
     CDS             3863..4534
                     /gene="sdaAB"
                     /locus_tag="VQU19_001415"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HET2480651.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            4543..5415
                     /gene="sdaAA"
                     /locus_tag="VQU19_001416"
     CDS             4543..5415
                     /gene="sdaAA"
                     /locus_tag="VQU19_001416"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HET2480652.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIKNEKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            5437..6069
                     /locus_tag="VQU19_001417"
     CDS             5437..6069
                     /locus_tag="VQU19_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET2480653.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAMQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAVTWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            6095..6193
                     /locus_tag="VQU19_001418"
                     /pseudo
     CDS             6095..6193
                     /locus_tag="VQU19_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(6417..8267)
                     /locus_tag="VQU19_001419"
     CDS             complement(6417..8267)
                     /locus_tag="VQU19_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HET2480654.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMVDFWGLSASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVARAVDEAKVPKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(8335..9474)
                     /locus_tag="VQU19_001420"
     CDS             complement(8335..9474)
                     /locus_tag="VQU19_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET2480655.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKGKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDAEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGGLILKIDAHSKVTESFVMNNVAVIQQGEFVCGGPRP
                     TIVKGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLSLLTLLTLLKHK
                     NGFLIVMPFLLFSIHFAYGLGTIVGLIRGFKWKKEYKGTVIYLEK"
     gene            9532..10698
                     /locus_tag="VQU19_001421"
     CDS             9532..10698
                     /locus_tag="VQU19_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HET2480656.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTRLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TAMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPAVAALLLIDILMTVALFTVDRADKIL"
     gene            10837..11163
                     /locus_tag="VQU19_001422"
     CDS             10837..11163
                     /locus_tag="VQU19_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HET2480657.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWTLYTDTINGIIEGS
                     IRHDKN"
     gene            11150..11743
                     /locus_tag="VQU19_001423"
     CDS             11150..11743
                     /locus_tag="VQU19_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HET2480658.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEVAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVARFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            11736..12647
                     /locus_tag="VQU19_001424"
     CDS             11736..12647
                     /locus_tag="VQU19_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HET2480659.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            12710..13774
                     /locus_tag="VQU19_001425"
     CDS             12710..13774
                     /locus_tag="VQU19_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480660.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIADLDTPIGK
                     NTQVEEEVSQAEVELESQQEEKIETPEGGEARTEIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(13846..14706)
                     /locus_tag="VQU19_001426"
     CDS             complement(13846..14706)
                     /locus_tag="VQU19_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
                     /protein_id="HET2480661.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHIYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTETDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYEAIARLDYAKFLEVLPPSFYHQLDANQIEVQPILD
                     KDFKTLAQEK"
     gene            complement(14828..15814)
                     /locus_tag="VQU19_001427"
     CDS             complement(14828..15814)
                     /locus_tag="VQU19_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HET2480662.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEELWFKIDEENEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(16086..17561)
                     /locus_tag="VQU19_001428"
     CDS             complement(16086..17561)
                     /locus_tag="VQU19_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HET2480663.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(17665..18588)
                     /locus_tag="VQU19_001429"
     CDS             complement(17665..18588)
                     /locus_tag="VQU19_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET2480664.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(18602..19531)
                     /locus_tag="VQU19_001430"
     CDS             complement(18602..19531)
                     /locus_tag="VQU19_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2480665.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            complement(19850..20200)
                     /locus_tag="VQU19_001431"
     CDS             complement(19850..20200)
                     /locus_tag="VQU19_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480666.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKAFADDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETADKDVLENSQEELQKAVLFLADEKGSEHTEAELI
                     DNLKEVIAKLKANA"
BASE COUNT         6149 a         4355 c         3662 g         6142 t
ORIGIN      
        1 ccatcaaatt taccgtctac gatatctaaa ccatatgcaa tggctcctcc taatgagaaa
       61 acttcagcaa cagtagccgc aatattaaga gcattagtaa tagttgccat actaactcca
      121 ccaatatatc ttgttatagc acttctaacg actcggctca tcataccacg attagcaatt
      181 aactttttaa tggcatatgt ctggtatact gacatccctc cagaaactgc agctgcagca
      241 atattatcac gtttgttcca ccagttacaa ccaacaccac ccccatcaag atacatcatc
      301 tcttcttgct caagaacaac ataattattt ggtaatacga gttccattta ttttctcctt
      361 ttttattaag catagttagg atcgtttcct aacaagtgat cgttgacttt gtttatagca
      421 cttagttacc tagataagat atcctttagc ttgcttccaa aatttaagtc tgcacctata
      481 atatgagttc atattagtac tgctaaatcc tatctatagt aatgtcaaac acctaaataa
      541 agtcatctct ccaattcatt caagaaatga agaaaggcaa aaaatcttta aaataagaaa
      601 agtgcatatt atcaggtgtt caaaaatctt gataatatgc gttatataat agaaaaattt
      661 actcaatttc actttcaaat tgagtttttt cccaacctcg tttttaattt atatcttcaa
      721 taaaatctaa tgacctagtt gatatgtcat atggaataat attatttaat ctgtaatttt
      781 tttaaaaaac ttaataataa atttgctcca ctgattgcta tcaatatttc aattggtaaa
      841 aaatagtaat tccaaataaa atgagaaatc agcaatgata gaaaaataac aatatcaatt
      901 ttcctgttgt tgacatactc tgtaatttta tggtacagga atgcaacaat aactgaaatt
      961 aaaacaacca tcataatact attatcctat tctcaattga ttatcacgtc gcccatccca
     1021 gccatcaata atattggtaa aatccaatca gctccagcac caattccagc agatgcaata
     1081 cttctaataa cagtatttgc aaaagcattt ccaatatgaa ttcctaatac tcctaaacct
     1141 ttaacaatcc cagctaccag tgcggagcgt aatccataag atgcaagaac tagttgaagg
     1201 cctccacctc ctgctgctgc taatgctgca tatgctgcac cagtaatggc tcctgtaatt
     1261 gcccacctgg gtatatatat agccccccca tcaaggtaca tcatctcttc ttcatcaatc
     1321 acaacataat tatttggtaa tacgagttcc atttattttc tcctttatac tatgtaatac
     1381 cacaaaatga ttttgaccta aatcattctt aacttgaaga atcgcaggaa atgttaattt
     1441 tggagtcaaa tcttccagtg ctactcgaac agcttttact gtaaaattca acttattcag
     1501 acctgaaaca ataccactga cagtcgttcc atacatgtct gtaccaataa tttcccgaat
     1561 cttcatgatt gatagttcct ttttgtaaga taaaagaact gttgaaacaa ctgccgcagc
     1621 acaatctgac tgatcatgtt gcatcgtaca aggatatttt tttaacatag aaatactcaa
     1681 ttctttagaa ttaatctaac ttttctttga tgtcacccaa acctcaatca ctgcccagta
     1741 gttcttgaat cagtttattt tcaatcgtat cattctttgt tcttgatatc tttccaagca
     1801 ttgtagtaca gcagattttt gtccaaggac taagcctcct ttaacaactc aagctccctt
     1861 acattatatc gaccagcccc atggaaagat tatggccaga ctaatcaatg atataataca
     1921 tactagaata caaaatattt ttttattcat actttttctc ctatctttat tttctaccta
     1981 catcatacct cttattaagc tcattttaaa attacgttaa cttttttcac aaatttattt
     2041 cgactttctt ttttactttt tacattgcta tgatacaata tttttaacaa aattttattg
     2101 tttgttaact tttttcacag aaaggagaaa atcatgcgtt atgatttcgg aaaggtctat
     2161 aaagaaatac gtgagtcaaa ggggctgacc caagaagagg tctgtggggg tgttctctca
     2221 agaaccagct tatcaaaaat cgaaagtggc aagacaaccc caaaatatga aaatatggaa
     2281 tttcttctcc gtcaaatcaa tatgagtttt gaagagtttg aatatatctg tcaactttat
     2341 caaccaagtc aacgcacaga gattatgcaa acctatctca atatgcgttc cattatcggg
     2401 accagcgatc ttgtcaattt atttcaaaaa tgccaagact acctcaagac ccaccacgat
     2461 ctccctatag aagaaatcag agatatgctt gaagttgtta tttatctccg tcaacacggg
     2521 gcaggggaac tatcaaaaca cgcagaacag gttgtcaaaa aactttggaa aaaaattgaa
     2581 aaacaagata catggtatga gagtgatcta aaaatcctca ataccattct tttcagtttt
     2641 cccattgaat acctccatct catcactgga aaaatattgc aacgcctaga agtctataaa
     2701 aactatcaac atttatatga cttgcgaatg acaattctat taaacctttc cacactctat
     2761 ctatacaatc aagataaaaa catgtgtaag caaatctgct acactttact ggaggacgcc
     2821 aagaataaga aaagctacga taggctggct atctgctatg tccgtattgg gatttgtaca
     2881 gacgattcta aacttatcca aaaagggttc tcccttctgg agctaaccga ggaaacttct
     2941 atgctgtctc atctcaaaaa agaagtagag atctattacc aagcgaagga aagataaaaa
     3001 agccgaggga tttcctcgac tctttacata ttatttgttc gttagttctt aataccagcc
     3061 attgttaagc cagaagtttt tagcagcagt ccatgaaccg taacgtcctg caacgtaggc
     3121 atctgctaca cgttcttggt tttcagctga gtagtcaccg ttcaggtatg aatctgttaa
     3181 ttggtaacgt ccgatataac gtccatttgt agctgtatag ctaccacctg attctttttg
     3241 agcgatccat tctttggctt ctgcttcaga tccgcttaca gttgaaacaa ctgtttcact
     3301 tactactgga gctgaaacag tttcatcttg agcggctggt gccgcataag tagctggcgc
     3361 tggtgttgca acaggcgcta cagggccatc gataaccaac tcttgatcaa cataaatcaa
     3421 atgaatgtta tcaatgtggt tgttttctgc caatttttca actgttgtgt tgtgagtttc
     3481 agcgatttct gaaagtgtat caccttcttt aacagtgtaa gttgatgatt cttgagcaga
     3541 tacaaatgat ggagaaaata ctgcaaacaa ggcagctact cctgcaagag ttgctttaat
     3601 ctttttagtt attgatttca tattcgaaaa ttctccttct ttctatagtt ctatcatacc
     3661 ctttaaatat tactgtttct tgacactttt atgtagaaat attacaaaat tattttttat
     3721 ttccctaaat aaggtgtttt ttgtcataaa agatactatt tttatgctat ttgaggtatt
     3781 agaaaggttt tcatccacaa ttaaagccaa gcccctcatt ctttgatata atagagataa
     3841 gaatttttat aaggggaaac tgatgaaatc acttcgtttt caatctgtct ttgatatcat
     3901 cggaccagtt atgattggcc catctagtag ccataccgct ggtgctgttc gtattgggaa
     3961 gattgtctct tccatttttg atgatactcc gacagaagtt gaattccaac tttttaactc
     4021 atttgccaag acctatcgtg gtcacggaac agacctagcc cttgttgcag gtattttagg
     4081 aatggataca gatgatcctg aaattccaaa tagtctggaa attgcccaca agcgtggtat
     4141 caagattgtc tggaccattc agaaagacag caatgcccct caccctaaca ccactaaaat
     4201 tactgttaaa aatgcccaca agaccatcag cgtgactggt atttctatcg gtggaggaaa
     4261 tattcaggta accgaactca atggttttgc cgtctctctc aatatgaata caccgactat
     4321 catcatcgtt catcaagata ttccaggtat gattgccctt gttacagagg cgctttcccg
     4381 ctatggtatc aatatcgccc agatgaatgt cactcgtgaa aaagctggtg aaaaagccat
     4441 tatgattatc gaagttgaca gtcgcaactg tgatgaggct atcgaagaaa ttcgaaaaat
     4501 ccctcatctc cacaatgtca atttctttaa ataggaggaa gcatgtttta ttctatcaaa
     4561 gaattggtcg agcaagcaga tctggacttt caaggaaatg tcgcagaact catgattaca
     4621 acagagtttg aattgaccgg tcgcgaacgt gaagaagtct tccttctcat ggaacgcaat
     4681 ctggaagtta tgaaagcctc tgtccaactt ggcctcaatg aaaataaatc tcgtagtggc
     4741 ctgacaggtg gagatgctgc caaattggat cactacatca aaaacgaaaa aactttatca
     4801 gattacacga ttctctctgc tgcccgaaat gctatcgcag tcaatgaaca caatgctaaa
     4861 atgggcttgg tctgcgctac tcctaccgca ggaagtgccg gttgtctccc ttccgttctc
     4921 actgctgcta ttgaaaaatt agacctcagc cacgagcaac aattggattt cctctttgct
     4981 gctggtgcct ttggactagt catcgcaaac aatgcctcca tctcaggtgc tgagggtggg
     5041 tgtcaagctg aagttggttc agcctctgct atgagtgctg ccgccttgac tctggctgca
     5101 ggtggaacac cttatcaggc cagtcaagct attgcctttg tcattaaaaa tatgctaggc
     5161 ctcatctgtg accctgttgc aggtttggtc gaagttccct gtgtcaaacg taatgccatg
     5221 ggagctagct ttgctttcat cgcagcagac atggccttgg caggtatcga atctaaaatc
     5281 cctgtggatg aagtgatcga tgccatgtac caagtaggag caagcatgcc aactgccttt
     5341 cgtgaaacag ctgaaggtgg actcgctacc acccctactg gtcgtcgcct ccaaaaagag
     5401 attttcggag aataagctta tcaaatagga gaaaccatga cctctatcac agcgattttt
     5461 ttcgatttgg atggaaccct cgttgatagt tctatcggga ttcacaatgc ctttacctat
     5521 acctttaaag agctgggggt gcctagccct gatgccaaaa ctattcgtgg ttttatggga
     5581 ccacctctcg aaagtagttt tgcgacctgc ctgtccaaag accaaatttc tgaagccatg
     5641 cagatatatc gttcttacta taaggcaaaa ggcatctatg aagctcaact ctttcctcag
     5701 attatagact tgcttgagga gttatcgagc agttatccac tctacatcac cacgacaaag
     5761 aatacatcta ctgctcaaga catggccaaa aacttggaaa tccatcattt ctttgatggt
     5821 atttatggtt ctagccctga agcaccccat aaggcagatg tcattcacca agccttacag
     5881 acacatcaac tagcaccaga acaagccatc atcatcggag ataccaagtt tgatatgctg
     5941 ggagctcgag aaacaggtat tcagaaattg gccgtcactt ggggatttgg agagcaagca
     6001 gatctactaa actatcaacc tgattatatc gctcacaaac ccttagaagt tttggcgtat
     6061 tttcaatagc atagactggg cgacaactct atttcagaag aaaatgaagt aatactcaat
     6121 gaaaatcaaa gagcaaacta ggaaactagc tgcgggctgc tcaaaacact gttttaaggt
     6181 tgtagatgga actgacgaag tcagctcaaa acactgtttt gaggttgtgg atagaactga
     6241 cgaagtcagc tcaaaacact gttttgaggt tgtggataga actgacgaag tcagtaacca
     6301 tatacggcaa ggcgacgttg acgtgatttg aagagatttt cgaagagtat aagtctctac
     6361 ataataaaac gcatattacc aaggttattt aacttgataa tatgcgtttt tcttttttat
     6421 tcaatgtggg ttgtttgatt agcaaaggcg ataatagctt gcttcaactc atctccactg
     6481 agagtgcgga actctccaat cttttgattg atggattcta aaggcatgac attaacctta
     6541 ccaacgaaaa tcttatccat aacttgatta tcaacgagtt cggttgatac caagagttct
     6601 tcgtagagtt tttcacctgg gcggattcca acttcaacga ttggaatttc actttcagtg
     6661 tggccactta gaagcaccat cttcttggcc aagtcataaa tcttgactgg tttgcccata
     6721 tcaaggataa agacttcccc atctttggca taagcaccag catggataac cagacggcta
     6781 gcttctggaa tggtcataaa gtaacgggtc atgcggaagt ctgtcaccgt tacaggccca
     6841 ccttcagcaa tctgacgttc aaagactgga atgacactac cacggctacc aagaacattc
     6901 ccaaaacgaa ctgcacagta ggttgattgg ctacgttggt taaagccagt gacaatcaac
     6961 tccgccacgc gcttggttgc tcccataaca tttggtggat tgactgcctt atctgtcgaa
     7021 atcataacca tcttaggcac cttggcttca tcaacggctc tagcaacatt gtaagttcca
     7081 cggatattgt ttttgaaggc ttcttttgga ttgcgctcca tcataggaac atgcttgtgg
     7141 gctgccgcat gataaacaat agcaggtttg tactgctcaa agacttgcaa caaacgatca
     7201 tagtcttgaa tgtccgcaat cacaggtaca taatcaatcc cttggaactt acgaatcaat
     7261 tcatgataaa caaggtagat tgagttttcc ccatgaccga gcaagacaat gcgttcagga
     7321 ttgaagcgac taacttgacg acagatttca gaaccgattg aacctccagc tcctgtgact
     7381 aagatggtct tacctgtcag ttctgcaccc agacgcgatt cgtcaagacg gatttcctga
     7441 cgacccaaaa ggtccgtaat atcaattttt tggaagccag tacctgcttg gtgaaggccc
     7501 tgaacaacag tttcaacctt aggcatcttg taacatttga cacccagctt attacacatc
     7561 tgcaagatac gctcatattc tgacggatcc agcgacggaa tcgcaacgat gacacgctcg
     7621 atttgatggc gtttggctaa ttcaggcaga ttgtcataag agcccaaaac aggaatacca
     7681 ccaagttttt gacccttttt cttagaatcc ttatccaaaa taccgaccag ttctaattca
     7741 ctggttggat gttggtaact atccataaag agagccccac catcaccggc accaatcaag
     7801 aaggtccgac ggtgttctcc atcaccacta ccttttttgc gtctggagta gattaactgc
     7861 caagtaatcc gtggcaataa aatcaagaag gtactcaaca agataaagag aatgataaaa
     7921 cggatggaga agagtggcaa gaaggcataa cagatactat atgacaagac actgctagca
     7981 gtcacaccaa aaaagatttt catgaaatcc gtaatcttgc tgtaacgact aatactcgcg
     8041 ctcaagcccc aaaaatcaac catcaattga tagaacagga aggccaaact cgtatagata
     8101 atgtagtcaa caggtgctgg attaatcagc ccataaaata aaatataaga tacaatgatg
     8161 gaaaccacca tactgaaaat atcaaatatt ccccagaaaa cctgcttttg ttgtttattt
     8221 aaaatttcca ccagatcaat cacataatct gtgagttttt tattcataga aatttactcc
     8281 tccttaaaat agttctacta tattgttatt atagcacatt ttaatttatt tggcttattt
     8341 ttccaaataa attactgttc ccttgtactc cttcttccat ttaaatcctc taattaaacc
     8401 tacaatcgtc ccaaggccat aagcaaagtg aatggaaaat aaaagaaagg gcatcacaat
     8461 tagaaatcca tttttatgtt ttaataaagt cagcaaagtg agtaatgaca gtaatgataa
     8521 aagtagaaaa taggcaccta atagtaaagt tatgaatacg aatgtgatcg gtaacaatgc
     8581 tagactaaac acaagactca aaacaaataa acaaggaaca taatgaaata atgataaaca
     8641 cttaaactga acatgacttg tcaagccaat ccacaaacca tttgaatact tttgatgcag
     8701 cattttcttg aatgttggtc gaatatactg ataagataga atacttgggc tatagcggat
     8761 tttataacca tgttctcgaa ttctataatg aatatcatta tcttcagttc ggccaagttg
     8821 ctcatttact aaaccaacct tctggaaaac ctctcgttta tacatcccat gaaaaataga
     8881 agaaacatat ctatcctcgg aactatttcg ataattggca atgctactgc caaacatatt
     8941 ttcctcaaca agatgcaagg tctctgccca ttttcctttt cctttgacaa tcgtcggtct
     9001 aggccctcca cagacaaatt caccttgttg aataacagcc acattgttca ttacaaaact
     9061 ctcagtaact tttgaatgag catcaatttt taaaataagg ccccctacag aatgcttaac
     9121 tcccaggtta aaaccactag cttgattttt cttaggattg ttatacaatc taattgagtt
     9181 aaactctgca tcttctttta taaattgctg aatgatagct gtggtcccat ctgtggacat
     9241 agcatttata aatagaattt caatattctc tttaggatag gtttgatttt ttaagtcttc
     9301 aattagacca ggcagatatt tttcttcatt gtatgcactg attacaatgg atacgagaag
     9361 actttcaaca ttttgagtca ctactactct cctgaatttt cccttccacc attctatcat
     9421 aattttcaag acttttccat ttttatcttg aaagccagaa accttacttg acattatagt
     9481 gaaaaagcct taaaataagc tgttattaaa atcagctaga agagatatta tatgaaaaag
     9541 caatcactct tttttgttcc aggtattatc ctgattggtg tttccttgcg aactcctttt
     9601 actgttttac ccattatttt gggaaatatt tcgcaaggtc tggaggtaga agttagttcg
     9661 cttggtgtct tgaccagcct gcctctcctt atgtttaccc tcttttcacc attttctacc
     9721 cgactggctc agaaaatcgg cttggagcat ctcttcacct acagcctctt cttcttgacc
     9781 atcggctcac ttattcgact aatcaatctg cccctgctct atctaggaac cttgatggtt
     9841 ggggcaagtg tcgcagtcat caatgtcctg cttcctagtc ttatccaagc caatcaacca
     9901 aagaaaattg gttttctgac caccttatat gtaacgtcta tggggattgc aacggctctg
     9961 gcttcctatc tagctgtgcc cattacacaa gccagttctt ggaaaggact tatcctcctc
    10021 ctcacgttac tctgtctagc aacttttttg gtctggctcc caaatcaccg ctataatcat
    10081 agactagctc cacaaaccaa acaaaaaagt caaataaagg tcatgcgtaa taaacaggtt
    10141 tgggcaatta ttatcttttc aggttttcaa tccttgatct tttacaccgc catgacctgg
    10201 ttacctacca tgtctatcca tgcaggtcta tccagtcacg aagctggctt gctgacttct
    10261 atcttatctc tgattagcat tcctttttca atgaccatcc caagcctgac aaccagttta
    10321 tctactcgca accgtcagct catgctcact ctggtttcac tagctggtgt ggtcggcatt
    10381 tccatgctct ttttcccaat caataatttc atttactggc ttgccatcca tctcctcatc
    10441 ggaaccgcaa ccagcgccct cttcccttat ctcatggtca acttttcact caagaccagc
    10501 gcccctgaaa agacagccca attgtccggc ctatctcaaa caggaggcta tatcctagca
    10561 gcctttgggc caaccctctt tggttacagt tttgacctat tccactcttg ggtaccagct
    10621 gtagctgccc tcttgctcat cgatatcctg atgactgtgg ccctctttac agtggacaga
    10681 gcggataaga tcctttaaac ttctagtttt agctagaagt tttttatata taaaaatttt
    10741 acacatttct cttgacaggg ctttctttta gatgtacaat gtatgtgtag aaaaattata
    10801 tataaaaatc ttacacatta gaaaaggagg tttcccatgt actttccaac atcctctgcc
    10861 ttgattgaat ttctcatctt ggctgtactg gagcagggtg attcttatgg ttatgagatt
    10921 agccaaacca ttaagctgat cgctaatatc aaagaatcca cactctatcc cattctcaaa
    10981 aaattggaag gcaatagctt tctgacaacc tattctagag agttccaagg tcgcatgcgc
    11041 aaatactact ccttgacaaa cggtggtata gagcagctct tgaccctaaa agatgaatgg
    11101 acactctata cagacaccat caatggcatc atagaaggga gtatccgcca tgacaagaac
    11161 tgaatacctg actcagctag aactctatct caagaaacta cctgaagctg accgtatcga
    11221 agccatggac tatttcagag agctctttga cgatgctgga gtcgaaggag aagaagaact
    11281 catcgctagt ttgggaactc ccaaagaagt ggcccacgaa gttctatcca atcttctcga
    11341 taaaaaaatc aatgaagcac ccgctcaaaa aaataaccga caaattttac atatcgcctt
    11401 gttagccctc cttgcagcac ctatcggcat tcctctggga atcgccatcc tcgtgaccct
    11461 gttcgcaatc cttgtagccg ctttgactgt cattctggct ttctttgcag tttccatact
    11521 gggtatcatc ggcggattcc tatttttagt tgaaagtttc actgtcctcg cccaagccaa
    11581 atcagccttt atcttgattt ttggttctgg tttactggct atcggtgctt cttcgctagt
    11641 tttacttggc atttcctatg tagctcgctt cttcggtcta ctcattgttc gtctggtaca
    11701 atttgttctt aaaaaaggaa agagaggtaa tcagcatgcg taaatggaca aaaggatttc
    11761 tcatctttgg tgtggtgact accgttatcg gctttatcct gctttttgta ggtatccaat
    11821 ctgacgggat taagagccta ctttccatgt ccaaagaacc tgtctatgat agccgtacgg
    11881 aaaagctaac ctttggcaag gaagtcgaaa acctagaaat tactctccac caacacacgc
    11941 tcaccatcac agactctttc gatgatcaaa tccacatttc ttaccatcca tctctttctg
    12001 ctcaccatga tcttatcacc aatcagaacg atagaactct gagtctcact gataagaaac
    12061 tgtctgaaac tccgtttctc tcttctggaa ttggtgggat tcttcatatc gcaagtagct
    12121 actctagtcg ttttgaagaa gttattctcc gactaccaaa agggagaact ctaaaaggga
    12181 tcaacatctc agccaatcgc ggacaaacca ccatcataaa tgctagcctt gaaaatgcga
    12241 ccctcaatac aaacagctat atcctccgaa ttgaaggaag tcgtatcaaa aacagtaaac
    12301 tcacaacgcc caatatcgtt aatatctttg atacagttct tacagatagt cagctagagt
    12361 caacagagaa tcacttccac gctgaaaata tccaagtcca tggtaaggtt gaactgactg
    12421 ccaaagatta tctcagaatc atcctagacc agaaagaaag ccaacgaatt aactgggaca
    12481 tctcaagcaa ctatggttct atcttccaat tcacaagaga aaagcctgaa tcaagaggta
    12541 cggaattaag caacccttac aaaactgaaa aaaccgatgt caaggatcaa ctcattgcga
    12601 gatctgatga taatattgat ctaatatcca caccaagcag acgttgacaa aaacgcttac
    12661 atctgctact atggaagcat atttatctaa ctaaaaagga ggttctacca tgaaacaaga
    12721 atggtttgaa agtaatgatt ttgtaaaaac aacaagcaag aacaagcctg aagagcaagc
    12781 tcaagaggtt gcagacaagg ctgaagaaac gatagccgat ctcgatacac caattggaaa
    12841 aaatactcaa gtagaggagg aagtctctca agctgaagtc gaactggaaa gccagcaaga
    12901 agagaaaatt gaaactcctg aaggcggtga agcgagaaca gaaatagaag aaaagaaggc
    12961 atctaattct actgaagaag agccagacct ttctaaagaa acagaaaaag tcactatagc
    13021 tgaagagagc caagaagctc ttcctcagca aaaagcaacc acgaaagagc cacttcttat
    13081 cagtaaatct ttagaaagtc cttatatccc cgaccaagct ccaaaatcta gggataaatg
    13141 gaaagagcaa gtgcttgatt tttggtcttg gctagtggaa gcgatcaaat ctcctacaag
    13201 taagttggaa acaagtatca cacacagtta cacagccttt ctcttgctca ttctgttttc
    13261 tgcatcttcc tttttcttta gtatctatca catcaaacat gcttactatg gacatatagc
    13321 aagcattaac agtcgcttcc ctgagcagct agctccttta actctttttt ctatcatctc
    13381 tatcctagta gcgacaacac tcttcttctt ttcattcctc ttgggtagtt tcgttgtgag
    13441 acgatttatc caccaggaaa aggactggac gctagacaag gttctccaac aatatagtca
    13501 actcttggca attccaatct tcctcactgc tattgctagt ttctttgctt tctttgatag
    13561 cctacgattt acggccctct tgtgtgtgat tagcattgga atcattctgc ttgccagtct
    13621 ccatatcatt acaagaccaa gtcaagcaag tgaaaccgac tccttctatc aattattctt
    13681 gtctgtcctt gtgaacggag ttattatcct cctcttcttt gtagctgaag tggcactgat
    13741 tggagattat cttcgtatct tggcctttct ttaaaattca atcctgtcat ccttggcagg
    13801 attttttcta tgtcaaaaaa gcaagtcgat tgacctgctt ctgctttact tttcttgtgc
    13861 taatgtttta aaatctttgt ctaatatggg ttgcacttct atttgattgg cgtctagttg
    13921 gtggtaaaaa gatgggggta atacctctaa gaattttgca tagtccaagc gagcaatggc
    13981 ttcatagtct tctggtttag agccatctcc tgtgatttga accaagtcaa tctcccactg
    14041 cacttcctta tccaccaatt gctcaatata ggctgcagga acaaacggtt ctctcggtaa
    14101 aactgtcttg actccttgag ctagatggta aacgccatgc acttttcctt ctccatcctg
    14161 atagaaggaa actctcgcaa agtaggcatc tgtctcttga accgcacgca cacgcgcttc
    14221 aaactgagcc aaaccatctg cctctaaaaa gcttttcaag ttctcacgac taaagaaaat
    14281 aggattaaaa attccttggc aaatcgtaaa acgagctaca gggtctgcta gataggcttg
    14341 aatacttgct tggaaataag cttcaaaatc aaaaccatct agcccttcaa tatcagtccc
    14401 tgtataagca agcaaagcat ctaaaaatga cttgataatc tgccagtctg tctctgttag
    14461 taggtcagga agatcgacac ggtaagcctt ttgaccatca gcataactga ccttaaaaag
    14521 aaattgtgat tgccccacta tcgcacactc aatatactcg agacgattaa gaggctgacg
    14581 gagatagact acatcataga tatgtgactc caaaccgtct agcaatgcca agatcgactt
    14641 ggcattcaaa atctcttgtt ctcctaaaat gctctgttta tttggaataa aaaatgtttt
    14701 cgccataact ggactccttt gaaatcgctt acatacagta taccttattt ttctgaaaga
    14761 tacagaaaca aactttagat ttttgagtac aaagcataga aaaacagccc ctgaggactg
    14821 tttgatctta tacagtagct gcttgatcca agctttcacc gatagcggct aggcgctcga
    14881 tcacttcagc ttgtgtcaat tcattttttg aaacatagcg gttacgtggg tgaacacggc
    14941 actcgtgtga gcatccacga aggtacttgt cttcattttc ttctgatgtc aagatacgac
    15001 ggttacagaa gggatttcca cagttgacat aacgttcaca tggtgttcca tcaaaccagt
    15061 ctttccctac gatggttggg ttgacatggt tgacatcaac ggcgatacgc tcgtcaaata
    15121 cgtacatttt tccatcccaa agctcacctt gaacttctgg gtctttaccg taagttgcga
    15181 ttcctccgtg caattggccg acatctttgt agccttcacg gaccatccag cctgagaatt
    15241 tctcacagcg aacgccacct gtacagtaaa ccacgacacg cttgtccatg aatttttcct
    15301 tgttatcacg gacccattgt ggtaactcac ggaagttgcg aatatctggg cgaatagctc
    15361 cacggaaatg tcctaggtcg tactcataat cgttacgtgt gtcaaggaca acggtatctt
    15421 tatcaagaag cgcttctttg aactcttttg gagacaagta agcacctgtt gtttcaagtg
    15481 ggttgatgtc attgtcaaag tcgttgtctt ccaaaccaag gtggacaatt tctttcttgt
    15541 agcgaacaaa catcttcttg aaggcttgtt cattttcttc gtcaatcttg aaccagagtt
    15601 cttccattcc tggaaggctg tgaacgtagt ccatgtattt ttgagttgtt tcatagtcac
    15661 ctgaaactgt tccgttaatt ccctcgtcag cgactaggat acggccttta agaccgattg
    15721 atttacagaa agccaagtgg tctgcagcaa attgctctgc attttcaatt ggagtataaa
    15781 ggtagtaaag taagacacga atatcttttg ccataagatt tgttctcttt tctattctta
    15841 aattttctaa attttttatt tatccatact agtatacctg cttgagaaaa cgaatgcaat
    15901 ttatttgact ggaaattgta gaggattctc gaaatttcct gaatggttaa aataaggaca
    15961 agagaaaaca tggatatcta tatccttgtg ccaaaaaaac cactgccctc cccagaccaa
    16021 cctgaggaaa gcagtgattc ttattttagg agttaggaat gaatacacga aatcaattta
    16081 gctgattatt ttttgttttt caagaattca tcgtattgtt tttgcatttc gttcaatact
    16141 ttttcgtagg caccttcaga tttcaatttt tccatcaatt ctggaatcgc tttatctggg
    16201 tctacagtac cagtgttgat agctgtatca aattgttgca ttgtgttagc aatagctgag
    16261 atttcagatt tcacattgtc agtattgaag ataaatccaa gcgctggaga ttctttagct
    16321 tctgccaatt ctttcttaga attttcgatt tgttggtctg taacgttttc gttgatgtaa
    16381 aggatccagt tgttaccagt gttccatcca cccatgtgag tgtttccttt gtagccatca
    16441 agaacgcgaa cacggttttc tttaccttca attttttccc agttcttgcc ttctggaccg
    16501 taaacaagac cgttcaaaag ttctgggttc gtattcaaga ggttcaagat ttccattgat
    16561 ttttctttgt tcttagagtt gtttgagatg acaaagttag caacttgtgt tgtttggttt
    16621 ttcttgatga agttagtgat tggtttgatt tggatatctt tgttggcaac acgtgaaagc
    16681 aagctgttac cgtagtcagc tggtcctact gtttcttcac gaacgaacca agtatcttgt
    16741 tgaaggtcaa atgaagtatc gcttgttgcg acgtcttttg gaatgtagcc agcttcatag
    16801 aatttgtgaa gagtcttcaa gtgttctttg aaacgaggca cttcgtaacg gtttacaact
    16861 ttagtagtat cgccttcaag gtcaataacg aatggaagcc cgtttgctac tgggtagtca
    16921 aaattatcag atgggatgaa aactttacca atagcaaatg gtactacgtc tggagctttt
    16981 tctttgattt gtttcaagac tggctcaaga gtttcgtaag aagtaacacc tgaaatatcg
    17041 ataccatatt tggcaaggag agttccgttg aaggcaaagt tttgagatga tgctacgttg
    17101 gctgcaactg gtacagcata aatcttacca tttacagtat tacccttgat ataagctgga
    17161 tcaagtgcct tgtaaaggtc tttaccttct tttttgtaca attctgtcaa gtcagcataa
    17221 gcaccttttt gagcatttac aatatagtta tctgcaaagg cgatatcata gttttcacca
    17281 gatgatgtga taactgacat tttcttacca tagtcacccc agccaaggta ttggatatcc
    17341 aatttggcac caactttttc ttcgatgatt ttgttggcat ttgctaacaa ttcatccaag
    17401 ttatctggtt tgtcaccgat ttggtacatt ttgataacag gtttgtcacc tgaatcagca
    17461 gcttttttgc tgttacctgt caaatttcca caagcagcaa gacctgcagc cagagcgact
    17521 acactagcag atgcaaaagc atattttttc cagtttttca tgataaaaac tccttttttt
    17581 atttttaaac ttataaacaa tgtaatgatc ttaacttcac acaagggaag ttgggaactg
    17641 agaaatgttc tttttcaata agcactattc tttcacacca ccgatagtca aaccttttac
    17701 aaagtagcgt tggaagaatg gatacaaaat cgcgattgga agggttgcta ccacaaccat
    17761 ggccatacga cctgtttctt tcggtagagc aactcccagt tgaccagtca agccgaccgc
    17821 tttggcaatg tagtccatat tttgttggat ttgcatgagc aaatattgca atggatacaa
    17881 gttatcactc ttgatgtaaa gaagggcgtt gaaccagtca ttccagaaac caagagctgt
    17941 caaaagcgtg atggttgcga tacctggtag tgacaatggc aaacagattt ggaagaaaat
    18001 ccgagcctca ctggcaccat cgatacgagc cgattcgaga atggcttctg gaatggtctt
    18061 cttgaaaaaa gaacgcatca agatgatatt gaatggtgag agaagcattg gaacaatcaa
    18121 ggcccaaaca gtgtcaccaa gctgaagtac acgggtcacc atgatataac ctggtaccaa
    18181 accagcgttg aacaacatac tgagaaggac gaagatggta aaaaatctgc gatacttaaa
    18241 ggttgtccgt gaaatagcgt aggcataggt tgttgtgata aagacatttg tcaatgtccc
    18301 aactacggtt acaaagacag agatgaagag ggcttgtagg attttatcct taaactgtgc
    18361 caaaaactca aaaccgtcta agccaaattg ggatgggaag aagctatagc cgtattggag
    18421 gaggcttttc tcgtctgtca ctgaaataat gataacgaat acaaaaggta ggatacaaga
    18481 gagggcaatc aaacccgaaa tgatactgaa gaagatatct gctttcttac tgaaggagtg
    18541 aatgccgaca ttatcaattt tttctttttt aattttcttt tttgccatat tctcctcctt
    18601 tctagaacaa agctgagttt ggatcgactc gtcttgcaag caagtttgat aggataacca
    18661 gaatcaaacc aacaacggat tggtaaagac cggctgctgc agccataccg atatctgctg
    18721 tctgagtcaa accattaaag acatatacgt ccaaaacgtt ggttacattg taaagctgac
    18781 cagcattgtg tgggatttga tagaagagac cgaagtctgc gcggaagata tttccgactg
    18841 caaggatggt caatacagtt acaagcggag tcaactgagg aatggttacg ttgcgaatac
    18901 gttgccactt gctagctccg tccactgtcg ctgcttcgta gtaggttgga tcaattccca
    18961 tgatcgtcgc atagtacatg acactgctat atccaaagcc tttccaaata cctaggaaaa
    19021 gtaggagata gggccagatg cccaggtcag cgtagaaatt gacttctttg agaccaagac
    19081 tttccaatag atgattgaac acccctttat caatatttag gaaggcatct gtaaagaaac
    19141 tgatgataac ccaagacaag aagtaaggga acaacataga agtttgaaaa atcttcacca
    19201 ttctcttaga acggagctcg ctgaggataa tggcaatccc tacagataca actaaaccta
    19261 gaaagataaa gccaagattg tagaggacag tatttcgtgt gataataaag gcgtctcttg
    19321 aactaaataa gaatctgaaa ttatcgagtc cgacccattt actatttatg atactatcta
    19381 tgaaaccatt actggtcatg tggtagtctt tgaaggcaac cacgttccca aatactggaa
    19441 tgtaaaagaa tagaatcaac cagagtgccc ctggcaaaac catcaagaga aagatccagt
    19501 tgtctctcaa tgtttttgaa aactttttca taatttcctc cctttttatt ttgatatcca
    19561 tctaaaaatt cttttttaga cttttgataa cgattacatt attagtatac tcctatttgc
    19621 aggttaggtt aaactcctaa ttatagaaaa aactccacaa attatgtagc agatttaaaa
    19681 ctttatcacc actatcaaac aaatgtccta aatcaattgt ttattttatc tctattagcc
    19741 cagtgatggc gtcactctgt tataagcatc caacaacggg gtatactgaa aaatctccag
    19801 actagggaac tcagcgatag ttcctaatct ggagattttt aatatgttat taggcgtttg
    19861 ctttcaactt agcaataacc tctttaagat tatcaatcaa ctctgcttca gtatgctcag
    19921 agcctttttc atctgccaag aacaaaactg ctttttgaag ttcttcttga gagttttcaa
    19981 ggacatcctt atctgctgtt tctttgcccg ctgtttgtcc tccatcctta gttgctgact
    20041 ggctttcctt aatggactct agggaagcaa tggcatcttt gactgtttgc aagatatcac
    20101 gtaaaccttg ctctgtcaaa ctatcatctg caaaagcttt cttagcctct gccaaaacca
    20161 gacgtgctga atctgtggta ggattcgata cacctgtcaa tgatctcaaa agattttcta
    20221 aagtttgagt ctgcttacta atactagact aaaatcaaaa agcattatat aacagtgata
    20281 tgaaatcaac taaagaagaa atccaaac
//
LOCUS       DAVBCA010000042        19587 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.042, whole genome shotgun sequence.
ACCESSION   DAVBCA010000042 DAVBCA010000000
VERSION     DAVBCA010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19587
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.042"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(20..667)
                     /locus_tag="VQU19_001432"
     CDS             complement(20..667)
                     /locus_tag="VQU19_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HET2480667.1"
                     /translation="MDFEYFYNREAERFNFLKVPEILVDREEFRGLSAEAIILYSILL
                     KQTGMSFKNNWIDKEGRVFIYFTVEEIMKRRNISKPTAIKTLDELDVKKGIGLIERVR
                     LGLGKPNIIYVKDFMSIFQVKENDLQKSKNLTSEVKDFNLRSKENELQEVKNLDSNYI
                     ENNKSKYSKREYSFGENGLGTFQNVFLAAEDISDLQIIMNSQLENYIRLPAKLES"
     gene            complement(776..1294)
                     /locus_tag="VQU19_001433"
     CDS             complement(776..1294)
                     /locus_tag="VQU19_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HET2480668.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENINSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            complement(1521..2390)
                     /gene="rsmI"
                     /locus_tag="VQU19_001434"
     CDS             complement(1521..2390)
                     /gene="rsmI"
                     /locus_tag="VQU19_001434"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HET2480669.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGTSAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFGS
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETPLKGECLLIVEGASQDVEEKDEEDLFLEIQARIQQGMKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            complement(2393..2710)
                     /gene="yabA"
                     /locus_tag="VQU19_001435"
     CDS             complement(2393..2710)
                     /gene="yabA"
                     /locus_tag="VQU19_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HET2480670.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            complement(2750..3640)
                     /locus_tag="VQU19_001436"
     CDS             complement(2750..3640)
                     /locus_tag="VQU19_001436"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HET2480671.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEMAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            complement(3637..4275)
                     /locus_tag="VQU19_001437"
     CDS             complement(3637..4275)
                     /locus_tag="VQU19_001437"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HET2480672.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVKVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
     gene            complement(4495..5292)
                     /gene="proC"
                     /locus_tag="VQU19_001438"
     CDS             complement(4495..5292)
                     /gene="proC"
                     /locus_tag="VQU19_001438"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HET2480673.1"
                     /translation="MKIGFIGLGNMGASLTKSVLQARPSDEILLANRSQVKVDAFIAN
                     FGGQTSNNEEIFEEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSEIFCQLLAKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMEAVHQAYKRTQELGK"
     gene            complement(5296..6558)
                     /locus_tag="VQU19_001439"
     CDS             complement(5296..6558)
                     /locus_tag="VQU19_001439"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HET2480674.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAVSFLPRLEQ
                     VLVADRKEAGLEPIQFRLDSKASQFVSGQAAQAQDFDTEFLDYILAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVTGDGQIRE"
     gene            complement(6568..7698)
                     /locus_tag="VQU19_001440"
     CDS             complement(6568..7698)
                     /locus_tag="VQU19_001440"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HET2480675.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSA
                     QVAAMVQADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMVEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGVFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDMLRFQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            complement(7781..9661)
                     /gene="cbpE"
                     /locus_tag="VQU19_001441"
                     /gene_synonym="pce"
     CDS             complement(7781..9661)
                     /gene="cbpE"
                     /locus_tag="VQU19_001441"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HET2480676.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDSRITNSERLWDNLYGYDKVLQT
                     AAEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRKDGFVNISTSYKPIPS
                     FQAGWHKSAYGNWWYQAPDSTGEYAVGWNEIEGEWYYFNQTGILLQNQWKKWNNHWFY
                     LTDSGASAKNWKKIDGIWYYFNKENQMEIGWVQDKEQWYYLDVDGSMKTGWLQYKGQW
                     YYFAPSGEMKTGWVKDKEAWYYMDSTGIMKTGEIEVAGHHYYLEESGAMKQGWLKKAN
                     DWYFYKTGGSRAIGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVPIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNSSTSQDLTSSTSQSSETSVNKSE
                     SE"
     gene            complement(9664..10551)
                     /locus_tag="VQU19_001442"
     CDS             complement(9664..10551)
                     /locus_tag="VQU19_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET2480677.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLVLAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            complement(10541..11002)
                     /locus_tag="VQU19_001443"
     CDS             complement(10541..11002)
                     /locus_tag="VQU19_001443"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HET2480678.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMFLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            complement(10999..11907)
                     /locus_tag="VQU19_001444"
     CDS             complement(10999..11907)
                     /locus_tag="VQU19_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HET2480679.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            11900..12097
                     /locus_tag="VQU19_001445"
     CDS             11900..12097
                     /locus_tag="VQU19_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2480680.1"
                     /translation="MFIFYPQLLYLFIIPYFRSFPKRKKEHPILLNYLHYLPFSRQSY
                     FQNQFKKISGYTPLQYRKEKR"
     gene            complement(12149..12820)
                     /locus_tag="VQU19_001446"
     CDS             complement(12149..12820)
                     /locus_tag="VQU19_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2480681.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISLSS
                     NQISLNETVEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(12874..13095)
                     /locus_tag="VQU19_001447"
     CDS             complement(12874..13095)
                     /locus_tag="VQU19_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HET2480682.1"
                     /translation="MILMTKNINLTNEELELIQGGADSYGKNPNGRYDWEIEPVLTLP
                     VHGFCPRGTYDLGYIGGGNHLCKGSAARF"
     gene            13367..14176
                     /locus_tag="VQU19_001448"
     CDS             13367..14176
                     /locus_tag="VQU19_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET2480683.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHITAIHKAIEKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYVIVNNGCSTHQTSDWGLVDWQELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            complement(14357..15232)
                     /gene="aguB"
                     /locus_tag="VQU19_001449"
     CDS             complement(14357..15232)
                     /gene="aguB"
                     /locus_tag="VQU19_001449"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HET2480684.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKLLAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYNLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(15242..16327)
                     /gene="aguA"
                     /locus_tag="VQU19_001450"
     CDS             complement(15242..16327)
                     /gene="aguA"
                     /locus_tag="VQU19_001450"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HET2480685.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVV
                     AFVGPAEVVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEERYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            complement(16324..17451)
                     /gene="nspC"
                     /locus_tag="VQU19_001451"
     CDS             complement(16324..17451)
                     /gene="nspC"
                     /locus_tag="VQU19_001451"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HET2480686.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDEDMEELLGITDHIVF
                     NSERQLRKHGARCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFESQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            complement(17451..18710)
                     /locus_tag="VQU19_001452"
     CDS             complement(17451..18710)
                     /locus_tag="VQU19_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HET2480687.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVEKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMLD"
     gene            complement(18707..19567)
                     /gene="speE"
                     /locus_tag="VQU19_001453"
     CDS             complement(18707..19567)
                     /gene="speE"
                     /locus_tag="VQU19_001453"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HET2480688.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEYDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQAFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGAFMLPKYVE
                     DILEEEEGKK"
BASE COUNT         5680 a         4507 c         3482 g         5918 t
ORIGIN      
        1 tggtattatc aatcatgaac taggattcta gttttgcagg aagtctaatg taattctcaa
       61 gctgtgagtt cattatgatt tgtaaatccg atatatcttc agcagctaaa aacacatttt
      121 gaaatgttcc aagtccgttt tcaccaaaac tatattctct cttactatac ttactcttat
      181 tattctctat atagttagag tcaaggttct taacctcttg aagttcattt tctttacttc
      241 tgaggttaaa atcttttact tctgaagtta agttttttga cttctgtaag tcattttctt
      301 ttacctgaaa tatactcata aagtctttaa cataaatgat gttcggctta ccaagtccaa
      361 gccttactct ttcgatcagt cctattcctt tttttacatc aagctcatct aatgttttta
      421 tggcagttgg ctttgagata tttcttcttt tcataatttc ttcgacagta aaatagataa
      481 atactctgcc ttccttgtct atccagttat tcttaaatga cattcctgtc tgtttaagaa
      541 gtatggaata aaggataatt gcttctgctg ataagccccg aaattcttct ctatcaacta
      601 atatctccgg tacttttaag aagttaaatc tttccgcttc tctgttataa aaatattcaa
      661 agtccatgca agatcacctc ccttcttaaa aatttgcaaa gaaaaagacg atagtttttc
      721 ttctatcgcc tttggtaacc atttttatga aattttttaa agttaaaaat ataatttata
      781 atactatctt cttccatttt ctgattttag ttctgaaagt tccaaaaggt gcaaccgtat
      841 ttacatgaat aaacttatac acttcccaag tcgctgtttt agtcgcttca tcagcccact
      901 ttctcatatg cggttcaaat aattcttcct cactcaacga atcaatcatt gcagagatag
      961 aattaatatt ttcatttaat tttgctttca actcttgcag agataaatga gcgtaggtat
     1021 ctgtgaacca ctgatataat tcaccaagtt gattccattt aaatttatcc gatggtgttt
     1081 ttacttgaag cccctttctt tcatcttctt cccatttaag aaccaagttg gtccaaccaa
     1141 cctgataagc aaggttttct gctggagttc tgtcaacttc atcagctctc ttatctttta
     1201 aattttctgg aatattatca aattctaaaa tatatttctc aaatgttttc tctatctcag
     1261 cttttagttc ttctttattt tcgtatgttc gcaaaaaatc accttctttc tgatttatca
     1321 atcctttgat ttaaaatgac cttatttttc tatttatacc ttctaagaac gctataactg
     1381 ctgctccaaa catcggtatt ccgtatgggc ttaataaaaa acttaatacc aaagcttcta
     1441 taccaagtga tacatcttta tattatcatc actaattaag ttaaacagaa acagacagaa
     1501 ttattacatc ctgtctccct ttattgtttt tcttcccaat cgtggtaggc agcgtagagt
     1561 tgactcttat tccactggta aatcttagct acttccttaa tagcttgatt tttcttcatg
     1621 ccttgctgga tacgggcttg gatttctaag aacaagtcct cctcgtcttt ttcctccaca
     1681 tcctgactgg caccttcaac aataagaagg cattcgccct tgagtggcgt ttcagcgatg
     1741 ctttccagta attcagaaat tgtacctcgt tggtattctt catagatttt ggtcaattcc
     1801 ctgaccaaaa caaccgagcg gtcaccgtag acttctaaca tattttccaa cgtgtctgct
     1861 acacgatgag gtgattcata aaaaatctgt gtttcaggat aatctttttt agagccaaaa
     1921 aattgcttct gttgacctga ttttctcggt aaaaaaccgt aaaagatatg tggctgtggc
     1981 gctaaaccac tggcaatcaa ggcagaaatt cctgcagagg tacctggaac agtcacaact
     2041 gcaatttctt cctcaatagc tgccttaact aaatcatgac cagggtctga aatgctaggc
     2101 aaaccggcat cagagacctg agcaatactt tgccctgctt tcaagaaacc aatcaaatca
     2161 ggaatttttt ccttggcatt gtgctcatga aaactgatct gcttggtgga aatgtcaaaa
     2221 tgcttgagca aaagccctgt attgcgcgta tcctcagcag caatccagtc cacttctttc
     2281 aaggtctgga tagcacgaaa agtcatatca tctagattgc caatcggcgt tgccactaga
     2341 tacagcttgc catagggaga ctgcccctta aaactttttt gaatttgcat gcttactccc
     2401 tgtataacaa ctcatcacag aacatacatt cttcgtcctg ctctcgacgt tgtccataaa
     2461 aatcattaca tacgtgaaat ccatcacggt aaatacgacg gacactttcg cgaacatgct
     2521 tggccttgac gggagcgtct gcttccacct cacccaagcg ttctcgcaac ttactatttt
     2581 ccaagcgaag agctgtattt tcttctacca agctcttgag atttttcttg atggcttcca
     2641 catcggctaa agttaccaat aattgttggg aaaaatcatc cagcgcgtca aataattctt
     2701 ttttgtccat aaaacagccc tttcctttct ttatcattca tttttgagtt tatatttctt
     2761 tcaagaccag atattccatg gcattttgaa agctgacatt agcttgccac atttttctag
     2821 cttctagtaa atcttgtaga atcactctta ctcttacctg caagaggtcc tgcccacaga
     2881 gaacttcaag aatccgtaaa acctgatcct gtttttcctt atcatctgcc aagttggcta
     2941 atttggcaac ctgtagataa ctttcttttt tcttagctac taaccaagtc agcaggcgtt
     3001 cactttcatc gaccaaggtc caaaaacttg cctgattagc caacttttct gcttcagctc
     3061 gcgattgact aaacttagct aaaagagtcg cttttttctt aacaagtccc atttgttcta
     3121 agagtaagat aagtttttct tcttgctttt taaagtggaa gatctgagtc cgacttcgga
     3181 ttgtcggtaa catcttttcc tcatcgctag tcaagaagaa aatataaact tcactctggg
     3241 gttcttcgat gaccttgagc agagaattgg ctgcgttggg atgcatttta tccgcttgct
     3301 cgatgataaa gacctgttgc tggctttcaa tccctgcttg agaaaactgt cccaccaatt
     3361 cccgaatacg ttctgtcttg atgacctgat tgactggctt aatcaaggtg acatctggaa
     3421 actcttcctg ttcaatcagc ttgcaacttc ggcatttctc acatggtaag acgccaactt
     3481 tatccgtaca aaagaggctc ttagctaaaa attgcgccat ttccaagctt ccaaagaaac
     3541 ctgaaaagag ataggcgtga ttgagctggt cttgttctaa gatacggaca aaacggtcaa
     3601 actgagctgg ttgccaagcc tttagttgat cttgtttcat ttggccaagc ccattccgtc
     3661 aaacaagaca gccttggtag tttccacaac ttgctccaaa gggagactag catcaatctt
     3721 gacaatgcga tttccctctt tatccagaag agaaaggtag ccttgacgaa cttttttatg
     3781 caagtccaac ccttccaaat ccaaacgatt aacctcgcgg tcactattag cagcaatacg
     3841 agccagccct tcttccacct cgatgtcaaa atagagtgtc aaatcgggtt tgaggccatc
     3901 tgtcgcaaac tgattgagcc agtcaatggc ttcaatatct aagccacgac caaatccctg
     3961 ataggcaaca gaactatcga taaaacgatc catgatgacc aacttgccag cttcaagggc
     4021 tggaagaact ttttccacca aatgctgtct gcgactggca atatagagaa gtagctctgt
     4081 tttagcatcc atctgagtat gacttggatc caaaatcact tcccgaatct tctccccaat
     4141 caagactccg ccaggttcac gggtcgtcag cacctttact cctttttcct ctaaaattgg
     4201 tagcagagcc tctaaaacac tggtcttgcc tgctccctct ggtccctcaa gagagactaa
     4261 aaatcctttt gacatgtcta actcatttct tttttactac ttctattcta tcaaaaaaat
     4321 aggggtttgt gacaatcttt ttgtcttctc atttcatact caatgaaaat caaagagcaa
     4381 actaggaagc tagccgcagg ctgtacttga gtacggcaag gtgaagctga cgcagtttga
     4441 atttgatttt cgaagagtat cagccaccat aaaagaggca gataaaacta cctcttattt
     4501 acctagttct tgtgttcgtt tataggcttg atgaactgcc tccatgactg tgcctcgaaa
     4561 agcatgcgct tctaggcttg ctacgccagc aatagtcgaa ccgcctggac tacaaacttg
     4621 atctttcaaa actccaggat gttgctggct ttctaggacc aattgcccag ctcctaccac
     4681 agtttgggct gccattttca aggctgtttc tcgtggtaat cccgtctgaa cacctgcatc
     4741 tgccaaggcc tcaataaaga gatagacaaa ggctggtcca caacctgcaa gacctgtcgc
     4801 tgcattgatt aagctttctc ctaattcaac caagagacca gccttggcta aaagctgaca
     4861 aaagatctca ctgtcctcag ccctgcaatt aggagacaag gcataactaa tcactccttg
     4921 cccgatagaa gcaggggtat taggcatcat acgaataatt cggtgttggc ttgggataag
     4981 acttgctagt ttttctaagg tcaatccagc tgccatcgaa atcaaaagaa gactttctct
     5041 tttttcaagg atggtctggt attgagaaag cagttcagaa aactgagcag gcttaacacc
     5101 tagaaaaatc acatctgctt cttcgaatat ttcttcattg ttagaagtct gaccaccgaa
     5161 gttagcgatg aaagcatcca ccttgacttg actacgattg gcaaggagaa tctcatctga
     5221 cggtctagcc tgcaagacag acttggttaa actagcaccc atattcccca aaccgataaa
     5281 tccaatcttc atctcttact cccttatctg tccatcacca gtgaccacat acttgtagct
     5341 agtcaattcc ttcaagccca taggaccacg cgcgtgcaat ttctgagtag aaatccccat
     5401 ttcacaacca agaccaaatt gtcctccatc tgtgaaacga gttgaggcat taacatacac
     5461 cgctgcagag tccacttgat ctgtaaagta tgctgcagct tcagcatttt ccgtcacaat
     5521 ggcatccgaa tgatgggtac tgtgggattc aatatgcgca accgcttctt ctaaactgct
     5581 cacaacctta acagctagaa tatagtctaa aaactcggta tcaaagtctt gtgcttgagc
     5641 agcttgacct gaaacaaact ggcttgcttt gctatctagg cggaattgaa ttggttccaa
     5701 cccagcttct tttcgatctg caaccaacac ttgctccaag cgaggaagga agcttactgc
     5761 tttgttttca tgaaccagca gaacctccat ggcattacaa acagaaggac gactggtttt
     5821 agcattgttg atgatagaca gcgccttgtc ttcgtctgca tccttatcca catagacatg
     5881 gacaatccca gttcctgtct cgataacagg tacaatcgca ttctcaacca ctgcattgat
     5941 caagccagct cctccacgag gaatgagaag gtctagatag cccttggcct tcatcatagc
     6001 ataactactt tcacggctag tatcctccac cagttgaatc acatttggat gaatagtagt
     6061 cgtctccaag cccttcttca aggctgtgac aatggcatgg gttgtttgat aggcatcctt
     6121 accactacga agaacaaccg catttccact cttaagagtc aaagcagccg catcagacgt
     6181 cacatttgga cggctttcat agataatacc gatgacaccc atagctacac gtttttttgt
     6241 gataaccaaa ccattttcaa gctgacttgt ttctaaaact tcaccgattg gatctggtaa
     6301 ggcaaccact tcacgaattc ctcttgccat cgcttctata cgatctgcat ccaaataaag
     6361 acgatccaac atcacatctg agattttccc cttagccgct gccatatcga gggcattagc
     6421 cgctaaaatt tcctcagtag cagccactaa gtgatcagcc atggctagca aggcttggtt
     6481 tttcacttct tcactagctg tgttaatcga ttttttaaca gcctgtacct gttcaaattg
     6541 ttcttgtcta ctcaccatag tttacctcta aaattctgta aaaagtagtt ggatttcagg
     6601 agtaatggaa atccagtcgt cacggtaaat caagacaccc ttggcttttt gaaaacgcaa
     6661 catatcctcc aaagcagatg ctccaaattg cacgcgtcct tttccaagtg attttccact
     6721 ttccttatca aatactgtca cgatatcacc gtaagaaaag actccttctg cttcaacgat
     6781 accagataag agaagactct ttccatgttg agagagagct tccgcagccc ctttatcaac
     6841 ccaaatagaa ccttgactct gagcatagaa ggcaagccat tgtttctggg tacgaagccc
     6901 cttctcttga gcaacaaagt aagaaccatc ctcggtctcc tctgccgcct caaccatgga
     6961 atctgatttc aaggatgagc agatataaac aggaactcct gattccgtcg cgatagttgc
     7021 agccttgatt ttggttaaca tacccccagt tccgtttgac gaaccagctc caccagccat
     7081 atcaataatc tcacgattga tggtctcgat tctctccaag cgtttggctc ttggatctga
     7141 attaggattt ccagtataga gaccgtccac atctgtcaag aaaactaaaa ggtctgcttg
     7201 gaccatcgcc gctacttgag cacttagagt gtcattgtcc ccaaccttga gctcatcaat
     7261 aacgacacta tcattctcat tgatgatagg aattgcccca cggttgagca aaaccgacaa
     7321 agcctgatgg gcatttttat aacgacgctt atccacaaag tcatcttggg tcagcaagat
     7381 ttgtgcagaa acgatttgac gcaagagaag attggtcgta tattcttcca acaaaagtcc
     7441 ctgccctacc gctgctgaag cctgtttatc agcaatttta gtcggacgct ttttaaatcc
     7501 taaggctcca aaaccagccg caatggcacc tgaagacacc aaaatcaact catgaccagc
     7561 ctcgtgcagc atagccaact gctgggtaat atcctttacc ttactacgtg ataaacttcc
     7621 atcctcattt gtcagagaag aagtgcccac cttaaagaca atccgtttgt atttcatagt
     7681 ctcactccga ttattcatat ttatccatta taacatgaat aacaggaaat agaaaagagt
     7741 tgataggaaa aagaaggccc taaaaccttc ttttctacta ctattctgat tccgatttgt
     7801 ttacactcgt ttcagagctt tgtgaagttg aggatgtcaa atcttgacta gttgaagaat
     7861 ttgtaacact ttcatgttga ctcgtttctt tattttcaag atcctttttc actacttctt
     7921 tggattcttt tatttctgaa tgacttgtag ttttaattgt agcagatttc tcgatcggaa
     7981 catccactaa ccaggcacca cttgaatcca cagtatagcc ttctggtgtc ttaccattca
     8041 caagtaattg accattttct ttcaagaagt accatttatc cttgtcttta atccaaccta
     8101 tagctcgtga accacctgtc ttgtagaaat accaatcatt tgccttttta agccagcctt
     8161 gcttcatagc tcctgattct tctagatagt aatgatgtcc agcaacttct atctcacctg
     8221 tcttcatgat accagtagaa tccatatagt accaggcttc tttatctttt acccagcccg
     8281 ttttcatttc ccctgatgga gcaaagtaat accattgccc cttatattga agccaacctg
     8341 tcttcataga gccatcaaca tccaaataat accactgctc tttatcttga acccaaccaa
     8401 tttccatctg attttctttg ttaaaataat accagattcc atcaattttc ttccaatttt
     8461 tagcagaagc accagagtct gtcaaataga accaatgatt gttccatttt ttccattgat
     8521 tctgtaacaa gatacccgtt tggttaaagt aataccattc accttcgatt tcattccaac
     8581 cgacagcata ctctcctgta gaatcaggcg cttgatacca ccagttccca tatgcactct
     8641 tatgccaacc agcttgaaaa cttggaatcg gcttgtagga tgttgaaata ttgacaaaac
     8701 cgtcttttcg aatatcaaaa actgttgcat catagtcttt gctggctgcg ttgattctct
     8761 caattcctcg ttctttgagc caattaacat actcactatc aacaccattt ttccaaggta
     8821 gactatccga agtttgaaca atcaaactcg gactcaaatt tttaatgaaa tccttggtat
     8881 ttgatttgtt ggtatcatgg tgatgattaa acttcatcaa atcaactttt ccaatgagag
     8941 gaccatactt gtcttctgct ccatgaacat tatctaaatc gcccccaagg taaattttct
     9001 tgccattgac tttcaccacg ctaatcaagg aattggaatt gtcatcccaa attttcttta
     9061 attcacccga tgaatcagtt tcattttcat aattatagag ctgaatatcc atgtccccaa
     9121 actgaaaatg agcatcccct tgtgtgatat tttgaataac tgaaacacct ttttctgcag
     9181 cagtctgtaa aaccttatca tagccataca gattatccca tagacgttca gaattagtaa
     9241 tacgactatc actatatttc ttaagataga ctcggtcaac tggataggta gacagtaatt
     9301 catcaacatt tccaatatga tcactgtggg tatgggtcac caaaataaaa tcaagttttt
     9361 ggacacccaa ttccttcaaa cgacgaaaga cacggtctgt tagaacatgc ttataagacg
     9421 tttcaattcc ttctctccat ggataacgag aatcacttcc atctgggaaa tcataatctt
     9481 ctcctgtatc caccatggca aaatgtccat tgctttcaag aataatcgca tcactgccac
     9541 cttcttgaac attgataaag tggattttat ttcctgaact ttcttgagcc tgaacattcc
     9601 cataccatga caaacctaaa aaagcgccta caagtgctaa actagttaat ttctttttca
     9661 ttcttacttt ctcaatctct ccaaggtttc cttaaaaatc tctgggatat ctgctttaaa
     9721 ttccaaggtc ttacctgttc tcggatgagt aaaacctaaa gtcttggcat gaagaaattg
     9781 tccatgtcct ttcaaagtct tgcgaggacc atagacctca tcaccagcga ctggatggcc
     9841 gatataagcc atgtggacac ggatttgatg agtgcgccct gtctccagtt gcaactctac
     9901 taagctataa tcgccaaagc gttccaagac gtgaaaacgc gtcactgcag gcttcccttt
     9961 agcagttaca gcctgtttct tacggtcttt ttcactccgg ccaatcggcg cttcaattac
    10021 accacgatca ttaggcagat ttccatgaac aatcgcccaa tatttgcgga gagacttttt
    10081 atctttgagt tcttgggcaa gtactagatg cgcatcatcg tttttagcaa tcatgagaag
    10141 acctgacgta tccttatcaa tacggtgaac aatccctgga cgcagaaccc cattgatacc
    10201 cgacaagtcc ttaatatgat acatgagggc atttactagg gttccactgg tatgaccagc
    10261 actcgggtgc acaaccattc cctgaggttt gttaacgaca gccacatcct catcttggta
    10321 gactatttct agcggaagat cctcagccac atactctaat acctctggtt ctggcacatg
    10381 gtaagtgacg acatcaccct cttggactgt gtatttagct ttcttgactt gaccattgac
    10441 caagacctgg cctgatttaa tttgttcatt cgcgagacta cgtgataatt ctgacaaatc
    10501 tgacaaagcc ttatccaaac gcagaccacc agtttcaatt ttaatttcca tttatttcct
    10561 cttttagcat tgcaatcaat aaaataatca ctccaaccgt cagatagcta tctgccacat
    10621 tgaaaattgc aaagttgata aagtcaaggt ggaacatatc cacaacaaag ccctgactga
    10681 ccctgtcaat aaagtttcca agaccacccg cgattattag agtcaaaccc aagaacatcc
    10741 agaatgagtc ctccatgtgt ttatgtaaat accaaatggc acctatcacg acaaccagag
    10801 taatgacagc gaataacagc tgctgatctt gtaagataga aaaggctgca cctcgatttt
    10861 gcaggtaggt caagctaacg aaattgggaa tccaggagcg cacttcaccc agtggaatct
    10921 gctggacgat ataggatttg accaactgat ccagcccaat taaaagcagt acaatgactg
    10981 ccactattgc tctttttttc atgatttcct cttttgatca aaatattctt gcatgacttc
    11041 tacgaagaga gtcccagctt gactaagctc cacttcttca cgtttaacat agaccatgcg
    11101 gttatctagg ttatccttga gacgaataac tgtaatgcca ttaacactgt cactatctaa
    11161 aaatccagaa cctgtcgcat aggcgtccgt ccgctccaaa ataccattca aggtggcacg
    11221 gtctgtcaca ttaaacatct gtgagctagc gctggtatcg acaaagttct ctgaataata
    11281 aaggtactcg tctttctctt gagtgaaacg aaccgttggt aaatccgcta aatcctccat
    11341 gactaattcc tctttctggg ctaaaggatg accctcacag agataaatat gggtatggaa
    11401 aggaatcaat tcgatgacct ccagacctaa cttttcaacc cgttgcataa tccccttttt
    11461 attttgattg ttgaggtaga taatcccaat ctcactatgc ccttgcgcca cttcatctaa
    11521 tatttgaaca gtagttgatt caaaaatacg gaagttctta tagtcaggat agcgctctga
    11581 aaaggccgta atagttggtg gtaagaagtc atagtgctgg ctagcaacgg aaaattcatc
    11641 tttttcttct tcaggattgg catactgatt ttgaaaaata tcaaatcctt taaccaattc
    11701 ttgcgctttt tcataaaatt ccatcccacg acgggtcaag aaagtccctg agctggtccg
    11761 acggaaaatc ttaaagccca actctttttc caaatcacga acagaaatag acagactcgg
    11821 ctgactaaca tacatctttt cagcagcttc acgaaaagta ccactattgg caatagccac
    11881 aacatagcgt aattgttgaa tgttcatctt ctacccccaa cttctttatc ttttcattat
    11941 accatatttt agaagttttc caaaaaggaa aaaagaacat cctattcttc ttaactatct
    12001 tcactatctg cctttctcac gccaatctta ttttcaaaat caattcaaaa aaataagtgg
    12061 ctacacacca cttcagtatc ggaaagaaaa acgttgacta tttgtgaaaa aagaaaatgc
    12121 cggaaaattc cgacattttt ttagtaagct aacttcctga aaataggagt aaccaaacat
    12181 cccagaaggc agtgatattg atgagaatat gaactagtat tggatagtag agatttttag
    12241 tcatgcgata caatagagct aaaatcagac ctccactagc ataaatgaaa aaagcaagag
    12301 gagttaaagc aaaattgata tgaatataac cgaaaataat agcagaaagc aaaacatctc
    12361 cgtaccaagg tgagtttttg aaaaaggttg tcataagcac acctcgataa atcaattcct
    12421 cagcaatagg ggcgatgaag caaacgatga gcaagaaata agggaactcc tgtctcccca
    12481 tcatttctac cgtttcattc aaagaaatct gatttgaaga cagggatatg aaatacgaaa
    12541 agaggaagtc agacatatat gaaatgatgt agcccagtaa aaggtagatg aagtacctca
    12601 gctgccactt gaaatgaaaa attttctttc ctgcaaaaac cagtagatag atgaccgcta
    12661 agaaaagaac tccgctctcc atcaaaagca gaatctgaaa aaattcacga cttgctggta
    12721 gatagggctt tgcgaggtga ttgaaaactc tccaaaacca agttgatttg taaaaaatta
    12781 aggacaatgc tagtaaaatt tgaatagccc gttttttcat attaaattct ctgctttctc
    12841 cacttatttc ttcatattac taataaattt tacttaaaat ctcgcagcac ttcctttgca
    12901 aagatgattg cctcctccaa tatatcctaa atcataggtg cctctgggac aaaatccatg
    12961 aaccggcaga gttaatactg gttctatttc ccaatcgtac ctaccattag gatttttacc
    13021 atatgaatct gctccacctt gtatcagctc taattcttca tttgttagat ttatattttt
    13081 tgtcattaaa atcatgatat atttcctcca ttattcttca gattagttga gtaatctgat
    13141 actcatacct acttacaaaa aaactattat attaagttgg ttttttaatt tgtctagttg
    13201 caacattgac aaacatagta tagcatatct ttgcgaaata tcctcttcaa atcatgaatt
    13261 gtcatcaaaa catcttaaac tataaaatca attagtctca agctttctat caatttcttc
    13321 tccaaaatat gctataataa tagcaaaaga taaagaagga agacctatga ttaaactact
    13381 agccttggat atggacggca ccctcctcaa tgaagccaag gaaatcccac aagctcacat
    13441 tactgctatt cacaaagcca ttgaaaaagg tgtcaaactg gttctctgta cgggtcgccc
    13501 ccttttcggt gtcctcccct actacaaaaa actgggactc gacctccaga atgagtatgt
    13561 gattgttaac aacggttgtt caactcacca gactagcgac tggggcttgg ttgactggca
    13621 agaacttagt ccagctgaca tcgaatacct ctatgacctt gctgaaaaga gtgatgttca
    13681 gttgacactt tttgacgagt cacattattt tgttctcggt ggaaagccca atcaagttat
    13741 tgaaaatgat gctaaactag tattttcaga cctgactgaa atttctcttg aggaagcgac
    13801 tagtggaaag ttccggatgt tccaaggtat gtttttagga acaaaagaac aaacagacga
    13861 ttttgagcag cgttttgctg aagagctttg ccaacgattc agtggagttc gttcgcagcc
    13921 tgtcatttat gaagcaatgc cacttggaac gacaaaggct actgctcttt cacgactagc
    13981 tgagattttg aagattgatt cctcagagat tatggccatg ggcgatgcta ataacgatat
    14041 cgaaatgctc cagtttgcag ggcttgggat tgcaatggga aatgccagcg attatgtcaa
    14101 atctcttgcg gatgccgtta cctcaagcaa cgaagaagac ggcgttgcgc gtgctattga
    14161 gaaatatatt ctataaaaaa gaaaagcaaa tagacagaag ttactgctat ttgctttttt
    14221 gctaatattt taaaatacgg actaatcaat agagaagaat agcgaatcat aaaaatcgat
    14281 ttactagatg ccatagtatc ttatagttgc taataagaag ttagtctagc agaatgaatc
    14341 tctcatttct cccacactaa tctgtaattt gtctatacat ttctggtctt ctatctcgaa
    14401 acaagcccca gtttaggcgt tcacttgctc ccttgtctag gttataagta gctaacagaa
    14461 cagcttcttc ttgtctttca gctcgttcta gaatagctcc tgtttcatcc gtcataaagg
    14521 aggaaccgta gaagtcaaga ctggaactct gtccgccatt ttcctcacta ggagtaacct
    14581 cctctaaacc ataacgattg gctgcgatga ctggaacaat attcgctgct gcgtgccctt
    14641 gcatagtacg ttgccagtga ccacaactat ctgtatccaa aattggctct gaaccgatag
    14701 ctgtaggata aaagagcaat tcagcaccat tcaatgcaag acagcgcgct gtttcaggga
    14761 accattgatc ccaacagata ccgataccaa tcttagcata gcgagtattc cagaccttga
    14821 aaccagtgtt accaggcgtg aaatagaatt tttcttgata ataatggtca tctggtatat
    14881 gggtctttcg ataaacgccc agcacttccc catctgcatc aatgacggca atagagttat
    14941 acaagacatt accatctttt tcatagaaac tgattggtaa aacaacttgt agttccttag
    15001 caagcaactt aaaatgctga atggcagtat tttccgctac agattgggca tactggtagt
    15061 agtcatactg acgttcctga cagaaatagg gatgttcaaa caactcgggc aagagaataa
    15121 tttgggctcc ttgctcagca gcctgacgta ctaaacgctc tgcggtttgg atatttgttg
    15181 ccacatcctt agcgcattgc atctgaatgg ttgcaactct tacatttctc atctttttct
    15241 cctattctgg aatttgttgg gtgatacagt ggatattgcc accacctaag agaatatctc
    15301 tggctggtat tccgacaact ttacggtctg ggaaacactt gctgaggata tctaaggcca
    15361 cttggtcgtt tacatcctca aactgtggaa ccaagacagc cttgttggcg atataaaagt
    15421 ttacgtagga agctgctagt cgttcacctg cgtatcgctc ttcttctcct tcttcataga
    15481 tgtagcctgg caaatcttct tctgtcacaa cttgtcgaac tgcagggata ggcaatttat
    15541 gaatggtgaa gtgacaacct tttgcatctg tttcctgttc taagagttcg agatctgctt
    15601 ttgacatggc atactgggga tcattttcgt catctgtcca agccaaaaca acctcagcag
    15661 gaccaacaaa ggcaacaaca ttatcgacgt gttcattggt ttcatcctga taaataccat
    15721 aaggaagcca aataactttt tcagcaccaa gactttctaa taatgtgttt tcaatctcct
    15781 ctttagtcaa gttaggattg cgaccaggac taagcaagca actttcagtt acgagaatag
    15841 ttccttgacc atcgctatgg attgcgcctc cttccagtac aaaaggttta gcatcataga
    15901 caggcctttc caaggcctca gcaaaacgac tggctacttg gtcatcctct tcataatctt
    15961 gataaagacc atcataggtg cctccccaag cattaaaggc ccaatccacg gctaatttct
    16021 tacctttatc attgacgaga atggttgggc cagtatcacg cgcccaggca tcattggtgg
    16081 gaatgtctaa ataaacaacc ttgtctccaa gataggattg ggcttcagat agataggcct
    16141 gctccaccaa aagatagact ctttcccctt ctgctatggt ctcgatgatc tgagtaaatg
    16201 ctcttttagc agcctttcct tgaaaaggcc atgatcctgg tcgagtcggc catatcatga
    16261 gggtaccatg atggggttcg tactctgctg gcatgtgata gcctaatttt tttggactgt
    16321 ccatcatgat aatctccctt taaagtcttg atagccaaaa gctttgagta agctacagtc
    16381 tccctgttcg tccatgagat agagacttgg caatccaata ccattaaagg tattattttt
    16441 gacaaaagaa taaatggcca tgtcttgaaa ataaagtctg tctccgattt ggactggatt
    16501 ttcaaaacta taatcaccaa tcacatcgcc agtcagacag gtattagaag aaagtctgta
    16561 ggtatgggct ttttcctgtg actcaaagcc atttctcaaa ggtggacgat agggcatctc
    16621 aagtacatca ggcatatggc aggtcgcaga ggcgtctaaa accaagattt ccataccgtt
    16681 ttctacaata tctaatacct cagttgctaa ataacccgca ttaagcgcaa tggcttcacc
    16741 aggctcgata tagatttcaa gattgtaagt ttttcggata cgcttgattt ctgaaatcag
    16801 caaatccaca tcgtaacctt ctcttgtaat atgatgacca ccacccatat tgagccattt
    16861 tacctcatgt aagtagggac caaactgttc ttctactgct ttcaaagttg tttgtaaatc
    16921 atctgctccc tgctcgcaaa gggtatgaaa atgaagtccg tcaaccaaat ctagcaaatc
    16981 gctcggaatc ttgtctatag taactccaaa gcgagaacca ggtgcacaag ggtcatagag
    17041 cgcgtgatct ccttgagttg aacactgagg gttgaggcgc aaaccaacac tgacaccagc
    17101 ctctcgacaa cgagccccat gcttacgcaa ctgtctctct gagttaaaga cgatatggtc
    17161 tgttatccca agcaattcct ccatgtcctc atccttgaaa gctggtgcaa aaacatggac
    17221 ttcaccagga aattcttccc ttgccaattt ggcctcatag agtccactag ctgtcgtacc
    17281 tgatagatac tggctaatca agggataagt tttgtagagg gaatatgcct tctgggcaag
    17341 caagaccttg caaccggcct cttcttgtac atattgtaga atgcggcaat tagcttctaa
    17401 cttggccaag tcaataacat aggctggtgt tggtacttgt tctaacttca ttagtccaac
    17461 atttgtggat tttcaaccac aacccatggc aaaccatact cattcaaagc ttccatgaat
    17521 ggatctggat ctaactcctc aaggttatac actccagctt gtttccaagt tccgttcatg
    17581 actaattttg tcccaatcat ggctggaacg cctgtcgtgt atgaaattgc ttgtgacccg
    17641 acttctgcat agcactcttg atggtcgcaa acattgtaga tgtagatagt cttttcaacg
    17701 ccatctttga cacctgtaaa gatacatcca atattggttt tacctacagt acgtggacca
    17761 aggctagcag gatctggaag caaggctttc aaaaattgaa ttggaacaat ttcttggccg
    17821 ttaaagttaa tggtatccgt acgaaggagt ccaacatttt caagacattt catgtgcgtc
    17881 aagtaagatt gaccaaaagt cataaagaaa cgaatgcgtt tgacacctgg aatgttcttg
    17941 gccaatgatt cgatttcttc atggtgaagg agatacatat ctttttgtcc aacttgaggg
    18001 aaatcatact cacgcttgat agacatagct tcgacttcga cccatttccc atcttcccag
    18061 taagaacctg gcgcagaaac ctcacggaga ttaatttctg gattaaagtt ggttgcaaat
    18121 ggataaccgt ggtcaccgcc attacagtct aaaatgtcga tataatggat ttcatcaaaa
    18181 tagtgtttga gggcataagc tgaaaagaca ctagttacac ctgggtcaaa accagaacca
    18241 agaagagcag tcaagcctgc ttctttgaat ttctcttgat aagcccactg ccatgagtag
    18301 tcaaagtagg ctgtaaaacc aagttcctta caacgttttt cgtagatagc acgccactca
    18361 gggtcttctg tgtcttctgc ttcgtagttg gctgtatcga tatagtgaac acctgttgcc
    18421 aaacaagcat ccataatggt taaatcttga taaggcagag ctacattcaa aacagcttct
    18481 ggtttgtagc tttcaatcag agcaatcact tcttcaacct tgtcagcatc aagagcagct
    18541 gtctcaatct ttgtacttgt tttgccttcc agtttagctt tcaagtcatc gcattttgac
    18601 ttggtacggc tagcaatcat aatctctgta aatgtttcgc tatcttgaca aatctttgaa
    18661 atagcaactt gggcaacgcc cccacaacca ataactagta aacgactcat ttttttcctt
    18721 cctcttcttc taaaatgtcc tcaacatact tgggcaacat aaaggctccc acgtgtaagt
    18781 ttgcagtgta gtattctgtg aaaagctggc gttttttcca gccttccttg tcaaaatctt
    18841 tgacagggtg gtattttttc gatgcaaatc caaacaacca atagccagct gggctagttg
    18901 gaatatgggc ctgataaacc cgactgattg gaaaggcttg attgaccttg cggtgcatgc
    18961 ttcggcaggc cgactcatcc tcgtcaaaga acggactccc atgctggtaa atcatgatgc
    19021 cgtcttcctt cagagctcga taactattgc cgtagaattc cttggtaaag agtccttccg
    19081 tatggccaaa tggatctgtc gcatcgttga tgataatatc atagtcatat tcgcagtttc
    19141 gcaaaaagcg tagcccattt tggtagtaaa tggtaacacg aggatcatct aggcctgcag
    19201 caaagtctgg gaaatactca cgacagacct cgaccaacat ctcatccggt tccacgatat
    19261 cgatttgttc cagttcagga tagagtgtta atacttgggc aacaccgccg tcaccacccc
    19321 caataaccaa tactttcttt ggatttgggt ggacagccat gggaacgtga acggtcattt
    19381 cattgtagac gaaatcatcc gcatctgaga acaagacatg gccatttaaa atcagtattt
    19441 tcccaaaagc tggcgtatcc aagacttcga tatcctgcca ttcacttttt ccagcgtaaa
    19501 gttgcttggc tgttctcaga gacaatttga catctggagt atgaacttca gaaaaccata
    19561 aatccatcta tttctcctta tattata
//
LOCUS       DAVBCA010000043        18942 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.043, whole genome shotgun sequence.
ACCESSION   DAVBCA010000043 DAVBCA010000000
VERSION     DAVBCA010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18942)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18942)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18942
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.043"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(146..397)
                     /locus_tag="VQU19_001454"
     CDS             complement(146..397)
                     /locus_tag="VQU19_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480689.1"
                     /translation="MPKTKTLAELADVILWSFDFANDHAHAFFMDNVEWSHADSYFLS
                     FVSDDVEERYIENVYLDSLSVKQKFKFIFDFGDEWRFEC"
     gene            complement(687..2567)
                     /locus_tag="VQU19_001455"
     CDS             complement(687..2567)
                     /locus_tag="VQU19_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HET2480690.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIQGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDGLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDIL
                     CPILDQHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            complement(2561..3430)
                     /locus_tag="VQU19_001456"
     CDS             complement(2561..3430)
                     /locus_tag="VQU19_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET2480691.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPDLENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNILCQEAIERMNRNLAQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQDVKKAVDNFVDTYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            complement(3514..6159)
                     /locus_tag="VQU19_001457"
     CDS             complement(3514..6159)
                     /locus_tag="VQU19_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HET2480692.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDERFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTDRYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELIVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFALECHQAQERFSAFRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVFRYYNMSQENVHISEHQQTILDLLE
                     RPYPVHSGPLDPQEIRTEFIKKEEI"
     gene            complement(6250..7530)
                     /locus_tag="VQU19_001458"
     CDS             complement(6250..7530)
                     /locus_tag="VQU19_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HET2480693.1"
                     /translation="MIYSKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETSQFDETF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIENYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSIDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            7701..9785
                     /locus_tag="VQU19_001459"
     CDS             7701..9785
                     /locus_tag="VQU19_001459"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HET2480694.1"
                     /translation="MKPLLETIDTRFGTASKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDIDK
                     ACFQPHYLKLFSLRYQIETQLTPTCYGASIRLNQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKTSAQADWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGKAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLETASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKENKWLDIHTEQNHSHFNFVKECRLDKTLVSTIQHQDLLKAE
                     QLTFTLSWLPNH"
     gene            complement(9825..11504)
                     /locus_tag="VQU19_001460"
     CDS             complement(9825..11504)
                     /locus_tag="VQU19_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HET2480695.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNLDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFDCRHLTDGLETSSWASDADLPIQLELDLGSPKTFDVIELREDLKLGQRIA
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGPLVEAQKVRVMITEAQSIPVLTKISLYKT
                     PGLSKKEVVQELAFAEKSLAVAKGETLHFRIERSESSSSLEAKISIQPGTGVHGVAYQ
                     DEIYVLAFQAGETEKRLTLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            12259..13488
                     /gene="arcA"
                     /locus_tag="VQU19_001461"
     CDS             12259..13488
                     /gene="arcA"
                     /locus_tag="VQU19_001461"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HET2480696.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESDYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELILSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGNLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            13546..14562
                     /gene="argF"
                     /locus_tag="VQU19_001462"
     CDS             13546..14562
                     /gene="argF"
                     /locus_tag="VQU19_001462"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HET2480697.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            14727..15674
                     /gene="arcC"
                     /locus_tag="VQU19_001463"
     CDS             14727..15674
                     /gene="arcC"
                     /locus_tag="VQU19_001463"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HET2480698.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVIVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIVLTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            15883..17394
                     /locus_tag="VQU19_001464"
     CDS             15883..17394
                     /locus_tag="VQU19_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HET2480699.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYEA
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNTWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            17416..18747
                     /locus_tag="VQU19_001465"
     CDS             17416..18747
                     /locus_tag="VQU19_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HET2480700.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     PLYEQVCNGLKEAGYDYQSTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAEDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
BASE COUNT         5319 a         4291 c         3910 g         5422 t
ORIGIN      
        1 tgaaatacta agcctacaca gactgatttc aattttacca ttcttcatag tcaaaaccat
       61 cataatctgg atattgttct ggcaacgttc caaccgaacg tacgagataa gcttcttcgt
      121 cctctgtctc gatttctctc agcacttagc attcaaaacg ccattcatca ccgaagtcga
      181 aaataaactt aaatttttgt ttgacactta ggctatccag atagacattt tctatgtaac
      241 gttcttcaac atcgtcacta acaaagctaa gaaagtaaga atctgcatga ctccactcaa
      301 cattatccat gaaaaatgca tgagcatgat catttgcaaa atcgaaactc cataaaatca
      361 catctgctag ttccgctaac gtttttgttt ttggaatcta tatatgtcgg tagcaacctt
      421 ttttaatttg acggaaatga tccaagcttc tacagatgct ggcttttcag cttctatttc
      481 ttgttttact aattttaact gtagcatttg aaaccagata attcttctgt ttcacgcgaa
      541 acaccctgcg ccaagcaagg tgttcttgtt tttatactca atgaaaatca aagagcaaac
      601 taggaagcta gctgcaggct gctcaaaaca ctgttttgag gttgtagatg gaagctgacg
      661 tggtttgaag agattttcga agagtattaa gtcgtataaa tcgtcgaagc tgtcgcaatg
      721 gtatgccact ggttagctgt agttgctgcg aaatccttgt ctgcgtagaa gtcagtaaat
      781 ggtaggattt caacttccag ctcgtcgatg cggtcaagct ggccagccag ataaacctcg
      841 atacggcttt ctgctcgttt gatgcgttgc aagagtccgc ccatacggat gtcaactgta
      901 tccaaaccaa agaccttgtt ttctttcagc cattggtgac taaagagggc atggaagtct
      961 tcaatttggc ttctaagttc tggtaattct tgtctggcga tttgttgtaa actttcttta
     1021 tcatccgctt ggtaggcctg acgaatgcgt cgtcccacat ctactttgct acttaaaata
     1081 gcattcaact gggcctgagt ttcaaagaga taagcatagt ttccagcttt ttctttaatg
     1141 ttagcaagcg tctcagcagc ctgagcgaag tgcggtttgt cctgttcagg tgtcatgtgt
     1201 tgatcaagaa tcggacaaag aatatcctga taaaaaacat agcggttggg attgataccg
     1261 ctgagattgc ctggtaggtc tggtaagagg ttggcaaggt caatctgcat aaaatcctca
     1321 accgttagac cagtattggt cttgaagtgc gcagacaaac catctaggtc attgcgatag
     1381 ctgagttctg cccagatttg caagcttggt aggatagaga actgggcagt ttcaccacca
     1441 ttgtctcccc aacccgttac gatgacttct ttaatctgat tggcacggca ggctttatta
     1501 gcctcgatag ccactagacg gctaaaatgg ttgtgaggtg taaagccaat ccacttccaa
     1561 gctccccctg caaatgcaag gtcatggcta atcttgtgat gattgcggaa attacggttg
     1621 tatttttcct cgctatcctg ataataatcc cagtaaacca gagtcacacg gtctttgaga
     1681 cggtctaggt agacacgagt ttcctctgga atttccacat cacggtcgta ctggccatcc
     1741 gctgacatga gtttgaagaa catatcactc cacatctggc agtggaaacc atatttgtca
     1801 gcaatatcca gcacgcgctc caagtgttgg cacatgagga gactacgatc cacaacaccg
     1861 ttcaaaatca ggtagcgtcc caaaccaacc aagtgggctt cgtccatccc gatattgacc
     1921 ttgcgagtct tcagtttaga caacgtggca aacatgccat caatcaggtc ataaaccttt
     1981 tcttcgccaa tgagaagaat gtcctctaca tcacggagct cctgcacttc cttgacaccc
     2041 catttgacaa aggccgacaa gtgggccaag gtctggatgc atggtacaaa ggtcatgtca
     2101 aactgttgag cataggcttc gatttcctgc aactcctctg ctgaataagc tccacggaaa
     2161 tagccaaagt aaggctgccc ttcaatctgg taagtgtctt ccatgtaaag ttcaaaggtt
     2221 gagtagccca tgagagccaa gacctcaatc atctgcttgg cagaagccac attcagcacc
     2281 gcatttcgag aacagtcaac catgtaagcc aaatcttcgt aagctgcttg ttcctcaatc
     2341 tctactttat cagcttctgc tagaactgtt accaacaagg ataaggcacg ataaagttgg
     2401 tgaggtttgc ggtaggtcaa ttgatagtga ccttcctcac cctggataga gatagaggct
     2461 tggtcagact gagtgacagc cacttccaca tctggtagag aaatatgacc ttttaaaacc
     2521 tcaatagctt gcgtttgttt gggactaagt cctgtaaatc ttaccattgc ttttcctcct
     2581 gtagccagtt gacaagagca ccgtagagat tggcatctgc gtgataggtg caggcctgga
     2641 taactggtgc gaccgtgtat tcttcgtagg tatcgacaaa gttatcaaca gccttcttga
     2701 catcttggat aaaatctgga ttttgactga tagagccacc cagactgatg acatctggat
     2761 cgatcagata ctggatattg agcaagcctt gcgccagatt gcggttcatg cgctcaatgg
     2821 cttcttgaca aaggatatta ccagctgcgg cctcttggta aatcttgcga ccgtcccaat
     2881 cagtatgacc agatttttca atcacgtatc gtaccatatt cccagttgat gctagttgcg
     2941 accagttatt aagtttttca gcaggggcaa gggttgtcat gtagccaaat tctccaccca
     3001 agccgtggcg acctcgatga agtctaccat tgataatcat ggctccgcca atccctgtcc
     3061 caatcacgac acaggctgca ttttcaagat ctggatgagc tagtagttca ctgagtccaa
     3121 cgcagttggc atcattttct aaatggacag gtagctgata agagctaagc gcctcatacc
     3181 aagaaaagcc atggatgtag ggcaccgcac tgaagccatc aatcacacct gtctcttgat
     3241 tgactgcacc tggaacgctc atagcaatcc cactgtaatc ctgttctgac aagcgttgat
     3301 ctagccacgc tagtaaatcc tccaagtttt caggcgttga aatacttgtc ttatccagta
     3361 ttttcccatc aggagtcaga ctggcaaact taatcccagt ccctccgata tcaatcgttg
     3421 caatggtcat tgtttttacc ataaaaaggg gcgaatcagc agttagttct tactttttcg
     3481 cccctccttt cttttgatgt ttactttttg aaattaaatt tcttcttttt tgatgaattc
     3541 tgtacgaatc tcttgtggat ccaatggtcc tgaatgaact ggatatggtc gctcaagtaa
     3601 gtcaagaatg gtttgttgat gttctgatat gtgcacattt tcttgactca tattatagta
     3661 acggaagaca tagccttctt cattttccgc cactttaaag gctgttggac aaacttgcgg
     3721 tatgctgaga acagaatggc tcaagaggct accagtcgca accacgcttc cttcctgtct
     3781 agcaagctga aggctggtaa acggtgtctg caaggctttg gcacgacgga aagctgaaaa
     3841 gcgttcttgg gcttggtggc attcaagtgc aaactcgact tcaaactcac gcaagcattg
     3901 tgcttctggc gttgggaagt agccccagtc acctagctca cctgatgcac gcaaaatggt
     3961 cacggcaatg gtgttatccc caaggatttc gtattcattc aatcccttat tggatacagt
     4021 cacccctttt tcatcgtcat acagactgac aaaagcttgt tggtgttgag gattttcagg
     4081 attttcccat gaagcagctg gtttgtttgg tcgtgtcacc acctcataga tactttcaga
     4141 atcattgctt ggacgcgtgt tatgagtctt gaccaagaga cggatacggt gatccttggc
     4201 agtgttagta aagcgagtct tgaagcggat ttgtggattg tcaacaaaga caatcaactc
     4261 agtttccaga ggaatgtttg tcaattcttc tgaccgtcca gcctcacgct tcataaactc
     4321 gatgatacct tgttgctctt cttctagctt ttcatccgca ctgacaggca cggtcaattc
     4381 atgtttgagc aagattttag catagcgatc tgtgttttcc aagacctcgt ggcccttaag
     4441 ctctgcaaag attggctctg ttccttttgg ttggaaatag atatactcgt ttccgatgtc
     4501 cccacggtct tcgaagcgga taaagtcttc ataggcttcg tgagttgtct tgtcatatac
     4561 tgtgatattg tcatccacac tcaccgttac gaatggtgta tcaatcactc cgttttggta
     4621 aataccctca cggtgttctt gttttccttc cagcaattgg aaggttgtcc aagaaagcgg
     4681 cgctaggtga actggaatgg tcacgcgcac ttgtcgagca atacgagctt ggcggaactt
     4741 gtcttttggt aaatcgtact caaaattagc tccgaggtct tcgattgtag cctctacagg
     4801 acgaccatcc aagtcctcca cacggtaact tggtaagata agagcagcca tctttttgta
     4861 gccttctgtt gggtgcaatt ccttgaaatc acaagtcgcc acatcaatca ctgtgctgac
     4921 agtatcgacc ttatcatgca agcctgtgtt aatgacagta aagagatagt cactttgagc
     4981 cttatccgta gcaattttac ccttccactc gttgagcaag ttacttttaa caaagtttcc
     5041 tacttggttg accttggcaa aacgcgtttc catctcgcgg tgaacttcgt ccacgctaca
     5101 gccacagata ctatcatgtg gcgcattctg caaaagtgtt ttccaagcat aggtcaactg
     5161 gtccttgtgg ttgtgtccac cagtgataat agtcaagggt tctaccactt gctctaggag
     5221 gttgctattt tcttggaagg cttgttttag gtaaatgcgg gatgaagaag tgttggcaag
     5281 tgtgtaccag ccatctgttt cctgactggt caactcgcct gtaacagttg ataagtgttc
     5341 aggaagcgca ccttctacag cttgaacata ttcatcaaaa gaactatgaa caaagattac
     5401 atccgggaag agttcatttg ccacacgaat ggcttcgctc agatttttct gtacaggctg
     5461 gtggtcacag ccgttcatca tcaaccattg gttggtcgaa gcgtaggcac gcacatctga
     5521 caatttttgt ttccagaagg tcaaggcctc atctttgtca actgggattt cattcccatt
     5581 actgtaccag ttggcaaaga gaatacctaa aacacgacta ccatccacac cctgccagta
     5641 catttctgaa aactgggatg taaaccgctc atcttcaagg acttggttgt caaatccaat
     5701 cggcttcaca ccacgaccaa aggctgccac gtgaatacct gatttttgaa ggatttgagg
     5761 agcttgtccc atatttccaa aggtatctgg aaagtagcca atctgggttg atttacccca
     5821 tttggcagct tcttgttgac caatcaaggt attgcggaca ttggcttcac tggagatcaa
     5881 gtagtcatcc tgcaagatgt aaaagggacc aattttaagt ttgccctcgt caatgtagcg
     5941 ttggaccttg tcgcgatttt cagggcgaat ttgtaagtag tcatcaagga caatagtttg
     6001 tccatccaag tggaaactct tgaactcagg gtcattttca aagagatcaa agagattgtc
     6061 aaacaattcc accaactgca tacgatggct ttcaaaaggc aagtaccact cacgatccca
     6121 gtgactatgt gagataatat gtacaacaac attttccatg aagtaaaacc tcattctaaa
     6181 tttaaatttt aacgttttaa atgtaaactt gtgattctga taagaatcgg ttgagctaaa
     6241 gcgagcccct tagcggatat ccaagtaatc caagaccaac tcacagaaca tcatgttagc
     6301 ccaggagaac cattcacgag agtagagggt cggatcatct acgtggaagc tttcgtgcat
     6361 gacacctgta ccaccatcgc aggcaaccag ctgatccagc aagaattttt tctctgcctt
     6421 atctcttgtt gtcaatcctt ggatagaaag ggcgattggc cagatatagc gatagaaggt
     6481 atgagaactt ccgagaccgc tagcgtattc tccttggtag aagtatggat tttcagagct
     6541 cagaatggta cggcgagtgg cttgatacac ttcatcatcg atcgaacagt agcccagata
     6601 gggcgcagct agtagacttg gtacatttgg atcatccatg atgctggcat ttcctaggcc
     6661 atctacttca aaagcgtaaa tcttttcgcc cttgctgttg gtggtgtaag cgtagttttc
     6721 gattccttct tggatttcat cctgaagacg cttggcatca gcaataacac tctggctatc
     6781 agctaggttt aatgctgcga agatttcttg cacataaccc aagactacta cagcaaacat
     6841 atttgacgga atcaagtaac tatactggca acagtcatca ctcggacgaa aagctgacca
     6901 agtcatacct gtcactgcaa agtcaggtcc aaagccatca tttaccaagg tgtcttcctt
     6961 acggtccgta tctcggacaa aacgataagg agagttcttg tggtcttgtt caactgtcca
     7021 tagatggaga atttccttag tcgctgcgac aaaagtttca tcaaactgac tagtctcgcc
     7081 agtctctttc cagaggagat aagccaactg caaaggatag caaagcgaat ccacctcata
     7141 cttgcgctcc cagatccagc cgttaaggtc tgtgtggtca gtctcgtggt gccctttcca
     7201 gttctcctca atgttgaagg agttagcata gggatccttg agtaccaagg tcatctgacg
     7261 tttgaccaaa cctgcaatgg tctgacgcag gagggcatct cttttagcta catgaaggta
     7321 gggtctgagt tgggctgtcg aatctcgaag ccacatggca ggaatatccc cagtcaagac
     7381 aaaagttgaa ccatcttcta agatttcaac cgtattgtcc aaggtatcgg tgtagcaacg
     7441 ctcaaagaca tcaacccact ctggatggtc cttggcccgc tctgctactt catctagcca
     7501 ttctctaaca atttctttcg aataaatcat cgtgcaattc cctctttcaa acaagtttca
     7561 tgttcagtat atagcttttg agacagaaaa tacatacaca aatgatagtc atttttctac
     7621 aaaatagtta tctttaaaac tccttttcta aaggccctct ttttctgata taatgtagaa
     7681 aaacagctaa aggaaagact atgaaaccac tacttgaaac catcgatacc cgctttggta
     7741 ctgctagcaa gcatgccttc tctcggggaa ataccctgcc atacacaggc gtgccttttg
     7801 ggatgaatta ctttgtgccc cagaccagtg accaggatgg atcttggttt tttgatccgc
     7861 atctgcctat ctttcagggg attcgattaa ctcaccagcc cagtccttgg attggggact
     7921 actcttggct ccttctgaca cctgtcacca gtcaactggg gggagacagc ctctttcacc
     7981 gccagtcttc ttatgatata gataaagctt gcttccagcc tcactatttg aagctctttt
     8041 ctctgcgtta tcagattgaa acccagctca caccgacttg ctatggtgct tctattcgtt
     8101 tgaatcaaaa gcaaggcaaa gccctctccc tctatcttca cgcagcagat gaactgacag
     8161 tagagcaagt agataagcgg actcttgccc tgcgacaaga aggtaaaact gaaactaaca
     8221 aaaattcgct aacgatgttc actgccctgc aaatgaacac ggatattctt gctatcagcc
     8281 aagaagctgg ggactggcga attgacttag caagtagtca aaccgagatg caactagcca
     8341 cttctttcat ctctccttct caagctctaa tcaatctacc tcaagaagat tttgatagct
     8401 gtaaaacaag tgcccaagcg gattgggaaa atctcctcca tcgttttgac attatagaga
     8461 caggagaggc tgaccgaacc ttctttgacc actgcctcta cagactcttc ctcttcccac
     8521 agacttttta tgaggttgat gagtcaggga aagccatcca catggatctg gctactggta
     8581 ctgtcaagcc tggtgtcctc tttagcaaca atggtttctg ggataccttc cgcaccacct
     8641 tccccctctt tgcccttatc ataccggagc actatcaacg ctttttagaa ggtttcctca
     8701 atagctaccg cgatactggt ttccttccaa aatggctggc tccagatgaa cggggtatga
     8761 tgccaggtac actgctagat ggcattatcg cagatagcgc ctgtaaggac atggcccccg
     8821 acctagaagg agaactcttc caagccatgc tcgaaacagc cagcaaagcc gaccctctcg
     8881 gcatcaatgg ccgccacgga ctagcccaat accaagaact aggttacctc tctaccgacc
     8941 accacgaaag tgttagccat actctagact atgcctatag tgacttttgt atcgccagct
     9001 gtgccaaaaa actagagaac atagaaatcg ctgaaaccta caaggctgct tcacaaaatt
     9061 accgccagct atttgacgct gagacaggtt acatgcgagc acgagacaat caaggaaact
     9121 ttcaccctga cttctctcct tatagttggg ggcgagacta cgctgaatgc tctgccattc
     9181 aagctacttt aggcgttctc cacgacatcc ctggcttaat ccaactgatg ggtggaaaag
     9241 aaacctttag caactatctt ttgaaagcct gtcaagatgc tcccctcttt gaaacaacag
     9301 gctatggtta cgaaattcac gaaatgagcg agatggctac tgctcctttt ggacaaatag
     9361 ccatttccaa ccagcctagt ttccacattc cttatctctt ccgctacagc gattaccctg
     9421 actacactgc ccttcttatc aagacgctcc gtcagaaagc ttttcaccca agttgggaag
     9481 cctatcctgg agatgaagac aatggtagtc tctctgcttg gtacatctgg tcagctctcg
     9541 gattttatcc aacctgtcca ggaaaaccaa gctatgatct cggaatccct ctctttgacc
     9601 atctacgagt ctacctagct aaagaaaata aatggctaga tattcatact gagcaaaacc
     9661 acagccattt taactttgtc aaagaatgcc gactggacaa aacactcgta tcaactattc
     9721 aacaccaaga cctcctaaaa gctgaacaac taactttcac cctcagctgg ctaccaaatc
     9781 actaataacc aaaagaacct ttgcatcgcg caaaggttct tcttttatga aacttggact
     9841 tgaagttgat ccacaagctg accatccacc gttaggttca gatagaaatc caaggtttta
     9901 tctcctgcga aatacaaggt tggtagcgtc agcctttttt cagtctcacc agcttgaaac
     9961 gcaaggacat aaatctcgtc ctgataggcg acaccatgga cacctgtccc cggttgaatc
    10021 gaaatcttag cctctaaaga ggagctactt tcactacgtt caatcctaaa atgaagagtc
    10081 tctccctttg ccacagctag gcttttttct gcaaatgcta gttcctgaac aacttctttt
    10141 tttgataacc caggagtttt ataaagggaa atcttggtca atacagggat agattgtgcc
    10201 tcggtaatca tcacgcgcac cttttgtgcc tctactagcg gacctcgcaa gaggcgctta
    10261 tgaccaactg tgaagcccct gccaaactcc tgccagacac catccacctc tacttgcaca
    10321 tgaaaagcag cgattcgttg ccctagcttc aaatcttctc ttaactcaat tacatcaaaa
    10381 gttttaggag aacctaaatc gagttctaac tggatgggca agtctgcatc gcttgcccaa
    10441 gagctggtct caaggccgtc tgtcaaatgg cgacaatcaa agtctgcgga aagagctgga
    10501 ccagatacct cagctcccag agccaaatct tctttataga gctcattgcg ataggtcgca
    10561 aattcataaa gtcgttcaat atcctttgca tcaaagagcc cagcttgatt cggcggaata
    10621 ttaagcaaga gtggagttcc tcgccctact gagtgaaagt agatttcgac caactcctcg
    10681 agagacttag gatcctgatc ctcatggtag aaccagcctg gacggatgga aacatctgcc
    10741 tctccgattg aaaaaatcgt gcccgaggga tccccgtgct gaagatagtt cagctctgct
    10801 tctgttccta gtttatcaag attcaccttt tgccacagtg gatcacctgc ataccctcgt
    10861 tcattgccaa tccagcggat actggtgcct tctgttgaaa aaatcaagca atcgccctgc
    10921 aggtcacgaa tggtttcaaa ccatttttca aattcataat taaccttttg cgcgccctct
    10981 cctctggcac catccatcca aacctcagcg aacttaccag cattcccata gttaggattt
    11041 gataagattt ccttcaactg agccagataa taggcattgt agtccgcttc tcggtccaca
    11101 tgatagaggg gactatgggc atcccacggt gacaggtaga cccccatatc catatcaaac
    11161 tctgtggcag cttgggatac ttcaaggagc aagtcgccct ttcctctcct ccaaggactg
    11221 accttaaccg aataatctgt gtgagctgtc ggataaagga caaagccatc gtggtgcttg
    11281 accaccaaaa tcaacttttt gaagcccgtt tccttgagca cacgaaccca ctcacgcgca
    11341 tccaactgac tcgggttaaa gcgctcagga tcctcctgtc cagtccccca ttcttggtca
    11401 taaaaggtat taggaccgaa gtggataaaa gctgctagtt catctcccag ataagctagc
    11461 tgagtctgac ttggtaacgg tccatgcggt ttgattttct tcatcgttat atatctcctt
    11521 cttttgcaac ttctcttgtt cacaaggtta tccacaggtt gtggataata aaccatgatc
    11581 taacagccag ctctttccaa ctccaactgg taggctcagg atttttctcc tcaatgttcc
    11641 ctcttcaaac agctctgtca tatggttctg ctaacacctc tcagaatgct actctccata
    11701 attattctca ggcttctttc aggtcattgt gtgaagacca ttcactctcc agacttttcc
    11761 acagattgtg aataagtgat tattctaagc tatcacctcg tcgactataa caaaaaataa
    11821 aaagagggtc aataagataa ttatctcttc ctaaatactc agaaaagatt ctataatttg
    11881 tacaattgaa caagaaatgc ttctccaaaa tctatcttca aaagaatgtt gcatcttttt
    11941 atcctttcac acaaacattt ctctttatac agatccaagt gataaccaga tgataattgg
    12001 acactttttg gtcatttgta tattttttga aaaatttttt aaaaaaattt tatatccttt
    12061 ttatagaagt ttatgcattt gtatctatgt attctatcct atgttatgta taataacata
    12121 aaattgtgct aaacatcata atttatatta ttttccgaga aattatagcc attgacatta
    12181 cctaggaatt gcgttataac atacatgtaa gcggtaccca aaatggtgcc aagtcaaaat
    12241 ttttaaggag gaaaatacat gtcttctcat ccaattcagg tcttctcaga aattgggaaa
    12301 ctgaaaaaag ttatgttgca ccgtccaggc aaggagttag aaaacttgtt gccggactat
    12361 cttgaaaggc ttctttttga tgatattcct ttcttggaag atgctcaaaa agaacatgat
    12421 gcatttgccc aagctcttcg cgatgaagga attgaggttc tctacctaga acaactcgct
    12481 gctgaatcat tgacctctcc agaaatccgc gatcaattta tcgaggaata cttagacgaa
    12541 gccaacatcc gtgatcgtca aaccaaggtt gctattcgtg aattacttca cggcatcaag
    12601 gacaaccaag aattggttga aaaaacaatg gctgggattc aaaaagttga attgccagaa
    12661 attcctgacg aagctaaaga tctaactgac ttagttgaat cagattatcc atttgcaatt
    12721 gacccgatgc caaacctcta tttcactcgc gacccatttg caacaattgg aaacgccgta
    12781 tcgcttaacc acatgtttgc agatactcgt aaccgtgaaa cactctacgg taagtatatc
    12841 ttcaaatacc acccaatcta tggcggaaaa gtggatttgg tctacaaccg tgaagaagat
    12901 acgcgtatcg aaggtggaga cgagctaatt ctttctaaag acgtccttgc agtaggtatc
    12961 tctcaacgta cagacgcagc ttctatcgaa aaacttttgg tcaacatctt caagaaaaat
    13021 gttggcttca agaaagtttt ggcctttgaa tttgctaaca accgtaaatt catgcacttg
    13081 gatactgtct tcactatggt agactatgac aagttcacta ttcacccaga aatcgaaggc
    13141 aaccttcacg tttactcagt tacttacgaa aacgaaaaac ttaaaattgt tgaagagaaa
    13201 ggtgacttag ctgaacttct tgctcaaaac cttggtgtag aaaaagttca tttgattcgt
    13261 tgcggtggtg gcaatatcgt agcagctgcg cgtgaacaat ggaacgacgg ttctaacact
    13321 ttgaccatcg cacctggtgt ggtagttgtt tatgaccgca ataccgtgac caataagatt
    13381 ttggaagaat acgggcttcg cttgattaag attcgcggaa gtgaattggt tcggggccgt
    13441 ggtggacctc gttgtatgtc tatgccattt gaacgtgaag aagtgtaatc gctgttcggt
    13501 attcgtcaat agaaaatgta aaaaatagaa agaggaaata ataaaatgac aaattcagta
    13561 ttccaaggac gcagcttctt agcagaaaaa gactttaccc gtgcagagtt agaatacctt
    13621 attggtcttt cagctcactt gaaagatttg aaaaaacgca atattcaaca ccactacctt
    13681 gctggcaaga atatcgctct cctatttgaa aaaacatcta ctcgtactcg tgcagccttt
    13741 acaactgcgg ctatcgacct tggtgctcac ccagaatacc tcggagcaaa tgatattcag
    13801 ttgggtaaaa aagaatctac tgaagatact gctaaagtat tgggacgtat gtttgacggg
    13861 attgaattcc gcggattcag ccaacgtatg gttgaagaat tggcagaatt ctcaggcgtt
    13921 ccagtatgga acggtctaac tgacgaatgg cacccaactc aaatgctcgc tgactacttg
    13981 actgttcaag aaaacttcgg tcgcttggaa ggcttgacat tggtatactg tggtgatgga
    14041 cgtaacaacg ttgccaacag cttgctcgta acaggtgcta tccttggtgt caatgttcac
    14101 atcttctcac caaaagaact cttcccagaa aaagaaatcg ttgaattggc agaaggattt
    14161 gctaaagaaa gtggcgcaca tgttctcatc actgaagatg ctgatgaagc agttaaagat
    14221 gcagacgttc tttacacaga cgtttgggta tcaatgggtg aagaagacaa attcgcagaa
    14281 cgtgtagctc ttcttaaacc ttaccaagtc aatatggact tagttaaaaa agcaggcaat
    14341 gaaaacttga tcttcctaca ctgcttgcca gcattccacg atactcacac tgtttatggt
    14401 aaagacgttg ctgaaaaatt tggtgtagaa gaaatggaag taacagacga agtcttccgc
    14461 agcaagtacg ctcgccactt cgatcaagca gaaaaccgta tgcacactat caaagctgtt
    14521 atggctgcta cacttggtaa cctttatatt cctaaagtat aattttagat aataaaccgt
    14581 ctaccaacag ctatgagggc tgcgactaat agctttagtc cggtcctctt ttatgtaatg
    14641 gtaatctatt atttcttata aaatatgtga aaaatcatta aattgaaatc taaacgcatt
    14701 ctattgagtg tgataaagga gaatttatgg caaatcgtaa aattgtagta gctttgggag
    14761 gaaatgcgat tctttcttct gacccatcag caaaggctca acaagaagct ttagttgaaa
    14821 cagctaagca tcttgtaaaa ttgattaaaa atggagatga tttgattatc actcacggta
    14881 atggacctca agttgggaat ctcttgctcc aacatttggc atcagactct gaaaagaacc
    14941 ctgccttccc actcgactca cttgtcgcta tgacagaagg tagcatcggt ttctggttga
    15001 aaaatgcttt gcaaaatgct ctcttggatg aaggcatcga aaaaaatgtt gcctctgttg
    15061 taacgcaagt tatcgtagat aaaaatgatc cagcttttgt taacttgagt aaaccaatcg
    15121 gtcctttcta ttcagaagaa gaagcaaaag cagaagccga aaagagcgga gcgactttca
    15181 aggaagatgc tggccgtggc tggcgtaagg tcgttgcctc accaaaacct gttgacatca
    15241 aagaaattga aaccatccgt actcttttaa ataatggtca agtcgtcgta gctgcaggtg
    15301 gtggcggtat tcccgtcgtc aaagaaaaca atggacattt gactggtgtc gaagcggtta
    15361 ttgataaaga cttcgcttcc caacgtttgg cagaattggt tgatgcagac ctcttcatcg
    15421 ttttgacagg tgtagattat gtatttgtta actacaacaa gccaaaccag gaaaaattgg
    15481 aacatgtgaa tgttgcccag ctggaagaat atatcaaaca agatcagttt gcaccaggta
    15541 gcatgcttcc aaaagtagaa gcagctatcg cttttgtcaa tggtcgtcca gaaggaaaag
    15601 cagttattac ttcccttgaa aatctaggcg ccttgattga atctgaaagc ggaacaatta
    15661 ttgaaaaagg ataagttgtt ttactaataa gatgtattct atttctagta tctttatatc
    15721 aaattagaaa ttattcttga aaacatgtac aatatttcaa aagatactag ttttagactt
    15781 taatatggta aaacaaatat aaatagaaag cgttttcttg aatgtttatt taagaaagta
    15841 gttggttttt tacactttgt tagacatcag gaggaaaaac aaatgagtga aaaagctaaa
    15901 aaagggttta agatgccttc atcttacacc gtattattga taatcattgc tattatggcc
    15961 gtgctaactt ggtttatccc tgcgggggcc tttatagaag gtatttacga ggctcagcct
    16021 caaaatccac aagggatttg ggatgtcctc atggcaccga ttcgggctat gctaggtact
    16081 catccagagg aaggttcgct cattaaagaa acgagcgcag cgattgatgt agccttcttc
    16141 atccttatgg ttggtggttt ccttggcatt gtcaacaaaa ctggtgctct tgacgtaggg
    16201 attgcctcta tcgtgaagaa gtataagggc cgcgaaaaaa tgttaatttt ggtattgatg
    16261 cctttgtttg ccctcggtgg tacaacttat ggtatgggtg aagaaacaat ggccttctat
    16321 ccactccttg tgccagttat gatggccgtt ggttttgata gcctgactgg tgttgcaatt
    16381 attttgctcg gttctcaaat cggctgtttg gcatctactc tgaatccatt tgcgacaggt
    16441 attgcttcag cgactgcggg agttggtaca ggggacggta tcgtacttcg tctgatcttc
    16501 tgggttacct tgactgctct tagtacttgg tttgtttacc gttatgcgga taagattcaa
    16561 aaagatccga ctaagtcact ggtttatagt actcgcaaag aagatttgaa acactttaac
    16621 gtagaagaat cttcatctgt agaatctaca cttagcagca aacaaaaatc agttctcttc
    16681 ttatttgtgt tgacattcat cttgatggta ttgagcttca ttccatggac agaccttggc
    16741 gttaccattt ttgatgactt taatacttgg ttgactggtc ttccagttat tggtaatatt
    16801 gtcggttcat ctacttctgc actaggtact tggtacttcc cagaaggcgc aatgctcttt
    16861 gcctttatgg gtatcctgat tggtgttatt tatggtctta aagaagataa gattatctct
    16921 tccttcatga atggtgctgc tgacttgctc agtgttgcct tgatcgtagc gattgctcgt
    16981 ggtattcaag ttatcatgaa cgacggtatg attaccgata caatcctcaa ctggggtaaa
    17041 gaaggcttga gcggtctatc ttcacaagtc tttatcgttg taacttatat cttctatcta
    17101 cctatgtcat tcttgatccc atcttcatct ggtcttgcca gcgcaactat gggtatcatg
    17161 gctccacttg gagaatttgt aaatgtccgt cctagcttga ttatcactgc ttaccaatct
    17221 gcttcaggtg tcttgaactt gattgcacca acatctggta ttgtgatggg agctcttgca
    17281 cttggacgta tcaacattgg tacttggtgg aaattcatgg gcaaactcgt agtcgctatt
    17341 attgtagtga ccatcgccct tcttctcctt ggaaccttcc ttccattcct ataaaatagt
    17401 gagtgaggtg attccatgaa aatagatata acaaatcaag ttaaagatga atttcttata
    17461 tcattaaaaa ccttgatttc ctatccttca gtactcaatg aaggagaaaa tggaacacct
    17521 tttggacaag caatccaaga tgtcctagaa aaaactttag agatttgtcg agacataggt
    17581 ttcactacct atcttgaccc taaaggttat tacggatatg cagaaatcgg tcagggagca
    17641 gagcttctgg ccattctctg tcatttggat gttgttccat caggtgatga agcagattgg
    17701 cagacaccgc catttgaagc aactatcaaa gacggctggg tattcggacg tggtgtccaa
    17761 gatgataaag gcccttcgct cgcagctctc tatgcagtaa aaagcttgct ggaccaaggt
    17821 attcagttca aaaagcgcgt acgctttatc tttggtaccg atgaggaaac cctctggcgc
    17881 tgcatggcac gctacaatac catcgaagaa caggccagta tgggctttgc acctgactca
    17941 tcttttcctc tgacctatgc tgaaaaaggg cttctacagg tcaaacttca tggccctgga
    18001 tcggatcaac tagagcttga agtaggaggc gcctttaacg ttgtaccaga caaggccaac
    18061 taccaaggtc ccctctatga acaggtttgt aacggtctca aagaagctgg ttatgattac
    18121 caatccactg aacaaaccgt aacggttctc ggagtgccaa agcatgctaa ggatgctagt
    18181 caaggtatca atgctgtcat ccgactagct accattcttg ctcctctcca agaacaccct
    18241 gctctcagtt ttcttgcaac acaagcaggt caagacggca caggaagaca aatctttggt
    18301 gatatagcag atgaaccttc tggtcaccta tcctttaatg tcgcaggtct catgatcaat
    18361 catgaacgtt ctgaaatccg tattgacatt cggactcctg tcttagctga caaggaagaa
    18421 ctagtagagt tgcttacaag atgtgcacaa aactaccaac tccgctacga agagtttgac
    18481 tatctagcgc ctctatacgt cgcagaagac agtaaactcg ttagcacact gatgcaaatc
    18541 taccaagaaa agactggcga taacagtcct gctatttcat ccggtggtgc cacttttgct
    18601 cgcaccatgc caaattgtgt agccttcggc gccttattcc caggagcgaa gcagacagaa
    18661 catcaggcaa atgaatgtgc cgttctagaa gatttgtacc gtgctatgga tatttatgcc
    18721 gaagccgtct atcgacttgc aacttaatca ggcaactgtt tctaccaaaa aaaatcgacc
    18781 gattaatgaa ctgcacccca aaagttagac agaataaatc taacttttgg ggtgttttat
    18841 tatgaaattg agttatgaag ataaagttca gatctatgaa ctaagaaagc aaggacaaag
    18901 cttcaaacag ctttcaaaaa gatttggtgt ggatgtttct gg
//
LOCUS       DAVBCA010000044        18752 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.044, whole genome shotgun sequence.
ACCESSION   DAVBCA010000044 DAVBCA010000000
VERSION     DAVBCA010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18752)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18752)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18752
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.044"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..338
                     /locus_tag="VQU19_001466"
     CDS             <1..338
                     /locus_tag="VQU19_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET2480701.1"
                     /translation="CLSETADKNWHKSDRIFVTNTGKTVHSSILSKSLQRANERLKKP
                     IPKHLSPHIFIHITISILSENKIPLKTITDRVGHPDSEVTNSIYTHVTKNMKDEAINV
                     LDKVMKKIF"
     gene            complement(830..1240)
                     /locus_tag="VQU19_001467"
     CDS             complement(830..1240)
                     /locus_tag="VQU19_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001124848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480702.1"
                     /translation="MPKKKIERISVIHREKILWLKWYFMRDKEKPKYSVLECKMFDAA
                     KNKDMLAYKKYATIKQITDIRVQTSEDDILTAIKEVYVYNHMNVIGACQRILFVSQSP
                     AYNKLNKWFETYSDLYFSIIPLPNMGAYHELVDS"
     gene            complement(1258..1635)
                     /locus_tag="VQU19_001468"
     CDS             complement(1258..1635)
                     /locus_tag="VQU19_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480703.1"
                     /translation="MRKYLKEIKELQELKELLSSRNTPEVIIVEGNDDLGEFFQVDGE
                     LFSDIELLENLKKWREWEVQVIVDDWCNRGLNEYETGILYFPKHEDKMDYIRFNKGLE
                     PLYHALDEPYTTISKSEWLKLLD"
     gene            complement(1577..2005)
                     /locus_tag="VQU19_001469"
     CDS             complement(1577..2005)
                     /locus_tag="VQU19_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000918209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HET2480704.1"
                     /translation="MAGNENDGLTSKQIKFIDAMLTEPTIDKACQKAGVSRATGHKYL
                     KVAAVKKTLRLKQDEMMDKTTQMLYLASSNAVSVLNDIMMDAKINPFIRTQAAKTILE
                     QSYKTHEIFGVVRQIEELRLEIEEVSKGDQRVTRTQGIIK"
     gene            complement(2049..2654)
                     /locus_tag="VQU19_001470"
     CDS             complement(2049..2654)
                     /locus_tag="VQU19_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480705.1"
                     /translation="MTFTTIKDDIKAFGKKKHGYMTGYIAKQEELHKQLQNGMIGEKY
                     AKDQLEAYKLEGDTYSRDTYNKIHAEIEKQHDLELEALKEKELSVTADDVAELTLLAS
                     MKMTKDELLGYFEKYKNKPLAIKKLWSIAEQYPEIAINLELFNAEQALESLILFFKRQ
                     LSYCHYSLLINGDKIQAVTTEMVVNSDAPELDRRLDEYLNK"
     gene            complement(2744..2917)
                     /locus_tag="VQU19_001471"
     CDS             complement(2744..2917)
                     /locus_tag="VQU19_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480706.1"
                     /translation="MTENKDNKLLEMMEKGFVLYSKNGIIKYIEIPDHGSIKLKAQDG
                     QLVYKEVTTGEQC"
     gene            complement(3516..4412)
                     /locus_tag="VQU19_001472"
     CDS             complement(3516..4412)
                     /locus_tag="VQU19_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HET2480707.1"
                     /translation="MKSLQSSLGNIETFKLDELCPKHEIQLTQIKGERHVVVGWNENG
                     EVIKEVRCIPPYCEQCQEEQKKQDEEDAIADNLNAKLYLQTYNVLMSNKSYVADEFKT
                     KTFDDFNAVTSEEKRFLEFAKGQVQKYLDGMRGNTLITGGTGIGKTLLSVAIAKGINE
                     GYKTKGEPKSVLFVSLTEMIKQIKEGWNYGKGATLTEFEATELMKSVDYLIIDDLGAK
                     NAVIKPKSDWEQDLLFDVLNNRENTIFNTNLDSDELKIVYNERNYSRILKGLEGNTFK
                     AFTIKDKRYSINQLKNKVKQLK"
     gene            complement(4424..5233)
                     /locus_tag="VQU19_001473"
     CDS             complement(4424..5233)
                     /locus_tag="VQU19_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HET2480708.1"
                     /translation="MAKTKVYFWLKIDKKFFDNIFIKRLKTVPGGYTMTVIYIRLMLE
                     SLESDCILYYEGYFNNLKEELALKLDVSEDDIDMTMAYFTKCGLIQIDEDKNAELPQA
                     KAMVMSETNWASYKREQRKKGKLEEVQPSLTFSNSCPTEIEKELEIEVDKEQSPTPST
                     INQDFVNLYKSFEAETGKALSPLQIQELQYMLEDFSPELIHEALKEAVSQGKANFAYI
                     KAILNRWKQDNLLTVELVRNSRAAREAKKQQTNQLEPTSYEDWIPTQEKPF"
     gene            complement(5308..5523)
                     /locus_tag="VQU19_001474"
     CDS             complement(5308..5523)
                     /locus_tag="VQU19_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480709.1"
                     /translation="MNELDISNTQAVFVTVILIGLLLYLNHRDRKKSAQLERENQQTI
                     ETPSEDLNPDYGRYIQLAGVDVWGRIE"
     gene            complement(5525..5725)
                     /locus_tag="VQU19_001475"
     CDS             complement(5525..5725)
                     /locus_tag="VQU19_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480710.1"
                     /translation="MTLDLDNMTQAEFDEAMAEIQLQSPNIFQLISDFVNKKVTSVEI
                     DDLLNMKRAEQVAYIKNYKARA"
     gene            complement(5722..5913)
                     /locus_tag="VQU19_001476"
                     /pseudo
     CDS             complement(5722..5913)
                     /locus_tag="VQU19_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841301.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(5902..6192)
                     /locus_tag="VQU19_001477"
                     /pseudo
     CDS             complement(5902..6192)
                     /locus_tag="VQU19_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424675.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
     gene            complement(6362..6514)
                     /locus_tag="VQU19_001478"
     CDS             complement(6362..6514)
                     /locus_tag="VQU19_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480711.1"
                     /translation="MKIVTFKPTKQIDGGFYLPGIDILFVSDKADAKSTEDVILFISR
                     NGLNKS"
     gene            complement(6525..6791)
                     /locus_tag="VQU19_001479"
     CDS             complement(6525..6791)
                     /locus_tag="VQU19_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480712.1"
                     /translation="MEILSKEIQLQGLQLLKQTLETLVELEKQRSSKLDLISRKELMD
                     LLGISATTLDNWEDLALKRYQTPMDGAKKVFYRLSDVYLFLAIK"
     gene            complement(7002..7184)
                     /locus_tag="VQU19_001480"
     CDS             complement(7002..7184)
                     /locus_tag="VQU19_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET2480713.1"
                     /translation="MLITLSLAEKVRIKRARLQLTKKAVSEQLGIKSQTLTKVENGNY
                     DASKRIYESVMTWLVE"
     gene            7246..7749
                     /locus_tag="VQU19_001481"
     CDS             7246..7749
                     /locus_tag="VQU19_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2480714.1"
                     /translation="MYKMNRIKQLRKENNLTQRELANETKIPYRTIQRWENGETDIKS
                     DAAQVLADYFGVSIPHLLGYSDLIADTDSDIKAMAYSHLLTFVDEKQIKEFEKEFIRA
                     NDNSDTFGDLGSGEKALEKYYQALCYLVPPFRDILARYSFLSLDEKKSVYNIIVGLSN
                     NLSKENK"
     gene            7823..8986
                     /locus_tag="VQU19_001482"
     CDS             7823..8986
                     /locus_tag="VQU19_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HET2480715.1"
                     /translation="MNIIEKIKKNGQRVYYASVYLGVDQLTGKKARTTVTATTKKGVK
                     VKARDAINTFAANGYTVKDKPTITTYNELVKVWWDSYKNTVKPNTRQSMDGLVRVHLL
                     PVFGDYKLSKLTTPILQQQVNKWADKANKGEKGAFANYSLLHNMNKRILKYGVAIQVI
                     QYNPANDVIVPRKQQKEKAAVKYLDNKELKQFLDYLDTLNQSNYENLFDVVLYKTLLA
                     TGCRISEALALEWSDIDLESGVISINKTLNRYQEINSPKSSAGYRDIPIDKATLLLLK
                     QYKNRQQIQSWKLGRSETVVFSVFTEKYAYACNLRKRLNKHFDAAGVTNVSFHGFRHT
                     HTTMMLYAQASPKDVQYRLGHSNLMITENTYWHTNQENAKKAVSNYETAISNL"
     gene            complement(9140..10444)
                     /gene="eno"
                     /locus_tag="VQU19_001483"
     CDS             complement(9140..10444)
                     /gene="eno"
                     /locus_tag="VQU19_001483"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HET2480716.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            10608..11054
                     /locus_tag="VQU19_001484"
     CDS             10608..11054
                     /locus_tag="VQU19_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HET2480717.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(11051..12166)
                     /locus_tag="VQU19_001485"
     CDS             complement(11051..12166)
                     /locus_tag="VQU19_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HET2480718.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIDVGGTASNDGGLGIAAGLGYQFYDRDGNVLP
                     ASGQSLLNLASVSTENCYKIPEGVQIHILADVVSPLCGHQGATYTFGNQKGRHPTMFA
                     VVDQAIQDFYEKFSPATLEIKGAGAGGGLAGGLCAFAQASIVSGIDTCLDLINFDKKV
                     SDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLPFENIQAV
                     FSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(12175..12504)
                     /locus_tag="VQU19_001486"
     CDS             complement(12175..12504)
                     /locus_tag="VQU19_001486"
                     /inference="COORDINATES: protein motif:HMM:NF019887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HET2480719.1"
                     /translation="MERLAKSLGIAYFTANQLEVKEGLLTGKLVGQIISPQVKKETLE
                     KWRKKLKLSKERTVAIGDGGNNLLMLKSAELGIAFCSKEMLKKEIPHHVDKRDFLEVL
                     PLIDCLE"
     gene            complement(12458..12820)
                     /locus_tag="VQU19_001487"
     CDS             complement(12458..12820)
                     /locus_tag="VQU19_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HET2480720.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHC"
     gene            complement(12879..14312)
                     /gene="glgA"
                     /locus_tag="VQU19_001488"
     CDS             complement(12879..14312)
                     /gene="glgA"
                     /locus_tag="VQU19_001488"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HET2480721.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGFERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(14309..15448)
                     /gene="glgD"
                     /locus_tag="VQU19_001489"
     CDS             complement(14309..15448)
                     /gene="glgD"
                     /locus_tag="VQU19_001489"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HET2480722.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTFLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPEK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVRTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(15438..16580)
                     /locus_tag="VQU19_001490"
     CDS             complement(15438..16580)
                     /locus_tag="VQU19_001490"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HET2480723.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            complement(16570..18498)
                     /gene="glgB"
                     /locus_tag="VQU19_001491"
     CDS             complement(16570..18498)
                     /gene="glgB"
                     /locus_tag="VQU19_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HET2480724.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEYGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAIVTELPDKKWRDGLWLARRKRWGFAERPVNIYEVHAGSWKRNPDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDIYHLDGIRVDAVSNMLYLDYDDAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFTSQLNQFYKDH
                     RCLWEIDTSYDGIEVIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
BASE COUNT         5568 a         3928 c         3158 g         6098 t
ORIGIN      
        1 attgtctaag cgaaacagcc gataagaatt ggcacaaaag cgaccgtatt tttgttacca
       61 atacaggaaa aacagttcat agttctatct tgagcaagtc tctccagcga gcaaacgaac
      121 gccttaaaaa accaattccc aaacatctgt cccctcacat cttcatacac atcactatta
      181 gcatcttatc agaaaataaa attcctttaa aaacaatcac ggacagggtt ggtcatcccg
      241 actctgaagt cactaattcc atctacaccc acgtcacaaa gaacatgaaa gatgaagcaa
      301 tcaatgtact ggataaagtt atgaaaaaga ttttttaaaa agttttgtcc cttttttgcc
      361 ctctaaatac aaaaatagcc cttcggataa aatccgaggg gctagaaacg ttgttaaatc
      421 aacggccgaa cttttgaatt tcatggttcg ggataaaata gttcactgaa ctattttatt
      481 ttttaaggtt atcataatat caaatagttc aattaaatac gctaaattac taatatactt
      541 tttacctttt tcattctaaa atgtaaagta caaacaatta caatatacta gagggggagt
      601 aaaaaaggta ataaaattga cgagttcagc aggcaaggga aatagcactt ttcatggtgt
      661 tattttttta attcagcaat ggagtagccg cttaattgat agaaacaaaa agcacctagt
      721 ttcctagatg ctagcacaat agcccggatt cgaaccggaa tctcctcaat taaggtgcaa
      781 tccctatata ctactcattg tgctttggtt cattatatca tacaatcaac tagctatcta
      841 ccaactcatg atacgctccc atattcggta atggaataat actaaaatac aaatctgagt
      901 aagtttcaaa ccatttattc agcttgttat aggctggcga ctgactaaca aataatatcc
      961 gttgacaagc tccgataaca ttcatgtgat tatacacata gacctcttta atggccgtta
     1021 aaatatcgtc ttcacttgtc tgtaccctaa tatctgttat ctgcttaatc gtagcgtatt
     1081 ttttataagc tagcatatct ttatttttag cagcatcaaa cattttacac tcaagaacac
     1141 tatacttagg tttttcttta tctctcatga aataccactt gagccataaa attttttctc
     1201 tgtgaattac tgaaatacgt tcgatttttt tctttggcat gattacctcc taaattatta
     1261 atctaatagc tttaaccact cactttttga gattgttgta taaggttcat ctagcgcgtg
     1321 atataaaggt tctaaacctt tgttaaatcg gatatagtcc attttatcct catgctttgg
     1381 aaaatataag attcctgttt catattcatt tagaccacgg ttacaccaat catcaacgat
     1441 aacctgcact tcccattcac gccacttttt aaggttttct aaaagttcaa tatcactaaa
     1501 taactcacca tcaacttgga aaaattctcc cagatcatcg ttaccctcga cgatgataac
     1561 ttcaggcgta tttctactac ttaataattc cttgagttct tgtaactctt tgatctcctt
     1621 tagatacttc ctcaatttct aacctcaatt cttcaatttg tcttactact ccaaaaattt
     1681 catgagtttt atatgattgt tcaagtatag tttttgctgc ttgagttctt ataaaagggt
     1741 taattttggc atccatcata atatcattga gtacagaaac agcattggat gaggctagat
     1801 atagcatctg tgtagtttta tccatcatct catcttgttt tagtctcaat gtctttttaa
     1861 cagctgcaac ttttagatac ttatgccctg ttgcccttga cacccctgct ttttggcacg
     1921 ctttatctat cgttggctca gtaagcatgg catctatgaa ttttatttgt ttagatgtaa
     1981 ggccatcatt ttcatttcct gccatctatt acctcctcgt tatcaaaata aaggggttgc
     2041 tagcccctct atttgtttaa atactcatcc aaacgacggt caagctcagg ggcatctgaa
     2101 tttactacca tttcagttgt tacagcttgg attttatcgc cgttgataag caaactgtaa
     2161 tgacaatatg aaagttgccg cttaaagaat aagattagac tttctagcgc ctgctctgca
     2221 ttgaataatt ccaagttgat agcaatttct ggatattgtt cagcaattga ccaaagtttt
     2281 ttaatagcaa gaggtttgtt cttgtatttt tcaaaataac ctagcaattc atcctttgtc
     2341 atcttcatac tagctaacaa ggtcagctct gccacgtcat cagctgttac gctgagttct
     2401 ttttctttta atgcctctag ctctagatca tgctgttttt caatttctgc atgaatttta
     2461 ttataggtgt ccctagaata agtgtccccc tctaacttat aagcctctag ctggtcttta
     2521 gcgtattttt cgcctatcat accattttgt aactgtttat gtaattcctc ttgtttagca
     2581 atgtagccag tcatgtaccc atgctttttc ttgccaaaag ccttaatatc atccttgatt
     2641 gttgtaaatg tcatgttatc ctccttacga aaaaataaaa gaggtatgac aaaagagcgt
     2701 taaactcaat tatcatacct ctggtttttc cagtcagtat ttattaacat tgttctccag
     2761 tggtcacttc cttataaact aactgcccat cttgagcttt tagcttaatg ctaccatgat
     2821 ctggaatttc aatgtacttt attataccat tttttgagta taaaacaaag cctttctcca
     2881 tcatttctaa taatttatta tccttgtttt cagtcatgaa tttctccttt atttcaagtg
     2941 tcccaacggg tacggttgta agctgagaca ttttagggct atctttgagc gacaaaaatg
     3001 tcgaaaagtc ttcagttcct gtataaccgt tattagtttt gtttgctact catttttgag
     3061 tcacaaatct gttaagcaaa aatgagtaat agctcgtaag ataagtaaat ctaatacttg
     3121 tattcctaaa gcgttgatat aactgatatt ttcaactatc caacgctctt tactaccctt
     3181 tttagtgtgc tttagctcat ttttgagctt ttttgagctt ttttgagttc cattttggga
     3241 atgcaaagca ggcgcgcacc gtgcatgctt ttttcttgct catagcctca ccctcagaag
     3301 tttgccgacc gagagcgtgg ggctttttat ttttgtataa ttaaaaacag ctgcacaatt
     3361 tttgtacagc tacgaccgag gcaggggcga cctgccgtac tttacactag ataatatcat
     3421 ctaggtagtc caactgtatt ttatcatatt aaaggctaca ttacaatttc tcaccctgtg
     3481 aagagtgtct atttttgttt aggtttgtaa gtcgattact tcaactgctt taccttattt
     3541 tttaactgat taattgagta tcgcttatct ttgattgtga aagccttaaa agtgttaccc
     3601 tcaagacctt ttagaatacg gctataattc cgctcgttgt atactatctt gagttcatcg
     3661 ctatcaagat ttgtattaaa tatagtattt tctcgattat tcagtacatc aaaaagtaaa
     3721 tcctgctccc aatcgctctt aggtttaata acagcatttt ttgcacctaa atcatcaata
     3781 attaagtaat caacagactt catgagttca gtagcttcaa actctgtaag tgttgcacct
     3841 ttaccataat tccacccctc tttaatttgt ttgatcattt cggttaggct tacaaaaagc
     3901 acactcttag gttctccttt tgtcttatac ccctcattta tacctttggc aatagcaact
     3961 gataaaagtg tttttccaat ccctgtacct cctgtgataa gcgtatttcc cctcatgcca
     4021 tcaagatatt tttgtacctg accttttgca aattctaaaa atcgcttttc ttctgatgtt
     4081 acagcattaa aatcatcaaa agttttagtt ttaaactcat ctgctacata gctcttattg
     4141 ctcatcaaca cattataagt ttgcagatat agtttagcat tcaaattatc agcaatcgca
     4201 tcttcttcat cttgcttttt ctgttcttct tggcattgtt cacaataggg tgggatacag
     4261 cgaacttctt ttattacctc tccgttctca ttccacccca ctactacatg tctttctcct
     4321 ttgatttgtg ttagctgtat ttcatgctta ggacacaatt cgtctagttt aaatgtctca
     4381 atatttccta aactagattg taatgatttc attttctgac ctcctaaaat ggtttttctt
     4441 gtgttggtat ccaatcttca tagctggtag gctctagttg attggtttgc tgttttttag
     4501 cctcacgcgc tgccctgcta tttctaacaa gttccaccgt caataaattg tcctgtttcc
     4561 aacggttaag gattgccttg atgtatgcaa agtttgcttt accctgactg acagcctctt
     4621 ttaacgcctc atggataagc tctgggctaa aatcttctag catatactgc aattcttgaa
     4681 tctgtaacgg tgacaatgct ttacctgtct cagcttcaaa agatttatag agatttacaa
     4741 aatcttgatt gatggtagag ggagtgggtg attgttcttt atctacttct atctctaatt
     4801 ctttctctat ctctgttgga catgagttgg aaaatgtcaa agatggttgg acttcttcca
     4861 attttccttt ttttcgttgt tcacgtttat aactcgccca gtttgtttca ctcataacca
     4921 tagcttttgc ctgtggtagt tctgcgtttt tatcttcgtc aatctgtatt aaaccgcatt
     4981 ttgtaaagta tgccatggtc atatctatat catcttctga tacatctaat tttagggcta
     5041 actcttcctt gagattgtta aagtagccct catagtataa aatacagtca ctttccaagc
     5101 tctctaacat gagcctaata taaataactg tcatagtgta cccaccaggt accgtcttta
     5161 gtctcttgat aaaaatatta tcaaaaaatt tcttatcaat ttttagccaa aaatagactt
     5221 ttgtttttgc catcgtcctc tcccttgctc atttataatt ctctaccttg attagtctta
     5281 atactcgctt gtcattcatt gttagactca ttcaattctt ccccatacgt ctacccctgc
     5341 aagctggata tatcgcccat aatcagggtt taaatcctcg ctaggtgttt ctatcgtctg
     5401 ttggttttct cgctccagtt gggcgctttt tttgcggtct cggtggttta aataaagcag
     5461 taagccaatc aaaatcacgg taacaaaaac cgcctgtgta ttgcttatat ctagttcatt
     5521 catgttatgc cctcgctttg taattcttga tgtatgccac ttgttcagct cgcttcatat
     5581 tcaacaagtc gtctatttcc acactggtta cttttttatt tacaaaatca gaaatcagtt
     5641 gaaaaatgtt tggactttgt agctggattt cagccattgc ctcatcaaat tctgcttgtg
     5701 tcatgttgtc taaatctagt gtcattgcat tgcctcctca aacttctcta taagacaact
     5761 tttatttgct ttctgagttc catttttaga gttaaaaaga atatatttta aggttacagt
     5821 agcctctaaa tactcctttt cagcatgctc tatatacgcc tgttgctctg cttcgttctc
     5881 aaaaaagtgc ttagcttagc gtttaaagaa tgctttgact aggtttagtt tgaattgccg
     5941 tactgcttcg gtattcttta gataagtgat cagcaaagta gcctgttgct cgttcagaat
     6001 ataggatttt ttaggttgtc ctctagtgtc taatttatgg attttaaatc caagtattcc
     6061 caactcttca aagtcaacct tattttctct tattaagcgt gtgatagtgt ggtgttgtac
     6121 gtcagcacat tcagcgatga tctcgcttgt ggtatacggc tctttcttgc cgtccatgta
     6181 gactagttcc attatggttc tacctcctgt ataaatttag ctagcttact ttttaattgt
     6241 ctcctctagc cctttttagc ctctacaacg gttttggcta acgtgttaga ggcttttata
     6301 acggcctgta tagctgtctc tatttcctcc gtggaatagt agctttgttt tctaatatca
     6361 tttaagactt gtttaaccca tttcttgaaa taaataaaat tacatcttct gtactcttgg
     6421 catctgcttt atctgagaca aatagaatgt caatgcctgg tagataaaac ccaccgtcta
     6481 tttgtttagt tggtttgaaa gtaactattt tcatttcata actcctattt tattgctaaa
     6541 aataaataca catctgacag acgatagaat actttcttag ctccatccat cggggtctga
     6601 tatcgtttaa gagcaagatc ctcccagtta tcaagggttg tagcacttat acctagcaga
     6661 tccattaatt ctttacgaga aattaaatct aacttactag atcgttgttt ttctagctca
     6721 actaaagttt caagagtctg tttaagaagc tgtaaaccct gtaactgtat ttctttagac
     6781 agaatttcca tttatatcct ccattttcct ttttataaat taagttgtct ttttcctcta
     6841 attttgataa aataagaaga gattatttag caaagggggt tgtccctttg ctaaatacct
     6901 aacaaaacca cgcgccttgc ctttgcttga gttttgttat ttttccttag ccgtgtacgt
     6961 tggtttggtc gcctgtacat ggctttttac ttgcgttaaa tttattctac tagccaagtc
     7021 atcacgctct catagatacg cttagaggca tcatagtttc cattctcaac ttttgttagt
     7081 gtttgagatt taatacccaa ctgctccgat actgcttttt tggttagctg taatcttgca
     7141 cgcttgatac gtactttttc agcaagtgat agtgtaatca acattggttt cacctccctt
     7201 ttttctccat ttttggcatt ttgtgttata atctctttag aaaggatgta taagatgaat
     7261 agaattaagc aattacgaaa agaaaataat cttactcaaa gagaacttgc taatgagact
     7321 aaaatccctt atagaaccat acaacgttgg gagaatgggg aaactgatat aaaatccgat
     7381 gctgctcagg tacttgctga ctattttgga gtatcaattc ctcacttact aggttatagc
     7441 gatttgatag cagatacaga tagtgatatt aaagcaatgg catactcaca tctactaact
     7501 tttgtagatg aaaaacaaat caaagaattt gaaaaagagt tcattcgtgc aaacgataat
     7561 agtgatactt ttggtgattt aggaagtggt gaaaaggcgt tagaaaaata ctatcaagca
     7621 ttatgctatt tagttcctcc ttttagggat atattggcta ggtatagctt tttgtcacta
     7681 gatgaaaaaa aatcagtcta taatattatt gttggtttaa gtaacaactt atcaaaagaa
     7741 aataaataac tttaaacatc atgtataaat acctaacaaa accacgcgcc ttgcctgctg
     7801 atggaaagaa aggtacaaat acatgaatat catagagaaa attaaaaaga atggccaaag
     7861 agtttattat gctagtgttt atctaggcgt tgaccaacta acgggcaaaa aagcccgtac
     7921 aactgttaca gcaaccacta aaaagggcgt taaagtaaaa gcgcgtgatg cgatcaatac
     7981 ttttgctgct aatggctata cagttaaaga taagccgaca attacaacat acaatgagct
     8041 tgtaaaagtt tggtgggata gttacaagaa tacagttaag ccaaatactc gccaatccat
     8101 ggatggattg gttagagtgc atttattgcc tgtatttggc gattacaagc tatctaaact
     8161 tactacgcct attcttcaac agcaagtaaa caaatgggct gacaaggcaa ataaaggcga
     8221 aaaaggggca tttgctaact actccttgct ccataacatg aataagcgta ttttgaaata
     8281 tggcgtagct atccaggtaa tacaatacaa cccagctaat gatgtcatcg ttccacgcaa
     8341 acagcagaaa gaaaaggctg ctgtcaaata cttagacaac aaagaattaa aacagtttct
     8401 tgattattta gacactctga atcaatcaaa ttatgagaac ttatttgatg ttgtcctgta
     8461 taagacttta ttggccactg gttgccgtat tagtgaggct ctagctcttg aatggtctga
     8521 tattgaccta gaaagcggtg ttatcagcat caataagaca ctaaaccgct atcaggaaat
     8581 aaattcacct aaatcaagcg ctggttatcg tgatatacca atagacaaag ccacattact
     8641 tttactgaaa caatacaaaa accgtcaaca aattcagtct tggaaattag gccgatctga
     8701 aacagttgta ttctctgtat ttacggagaa atatgcttat gcttgtaact tacgcaaacg
     8761 cctaaataag cattttgatg ctgctggagt aactaacgta tcatttcatg gtttccgcca
     8821 tacacatact actatgatgc tctatgctca ggctagcccg aaagatgttc agtatagatt
     8881 aggccactct aatttaatga tcactgaaaa tacttactgg catactaacc aagagaatgc
     8941 aaaaaaagcc gtctcaaatt atgaaacagc tatcagcaat ttataaaaaa taagggtgac
     9001 ccatttccgg gctaccctct tactatacca aaaattagta ggggtagtaa aaagggtatt
     9061 aaattataaa aagcactaag ggaaagcgcc ccaaagtgct tatttcaaag gctttatagc
     9121 ctataatcac ataaggagat tattttttaa ggttgtagaa tgatttcaat ccacgatatt
     9181 cagctacttc accaagttgg tcttcgatac gaagcaattg gttgtattta gcgatgcggt
     9241 ctgtacgtga aagtgaacca gtcttgattt gtcctgcgtt agttgcaact gcaatatcag
     9301 cgattgttga atcttcagtt tcacctgaac ggtgtgatac aacagcagtg taaccagctt
     9361 ctttagccat ttcgatagct tcaaaagttt cagtaagagt accgatttgg ttaactttga
     9421 taaggattga gttagcagca ccttcttgga taccacgtgc aaggtagtca gtgtttgtta
     9481 cgaagaagtc gtcaccaaca agttgtactt tcttaccaag acgttcagta agagctttcc
     9541 aaccatccca gtcgttttca tccataccat cttcaatagt gatgattggg tatttgttaa
     9601 ccaattcttc aaggtagtcg atttgttctg cagatgtacg aacagcagca ccttcacctt
     9661 caaatttagt gtagtcgtaa actttacgtt ctttatcgta gaattctgat gaagcacagt
     9721 caaatccgat aaatacgtct ttacctggta catatccagc agcttcaatc gcagcaagga
     9781 tagtttcaac accatcttca gttccttcga aacgaggagc gaatccacct tcgtcaccta
     9841 cggcagtttc caaaccacgt gatttaagga ttttcttaag agcgtggaag atttcagcac
     9901 cgtaacgaag ggcttcttta aatgttggcg caccaactgg caagatcatg aactcttgga
     9961 aagcgattgg agcgtcagag tgagaaccac cgttgatgat gttcatcatt ggagttggaa
    10021 gaactttagt gttgaatcca ccaaggtagc tgtaaagtgg gatttcaagg tagtcagcag
    10081 cagcacgagc tacagcgata gacacaccga ggattgcatt cgcacccaat ttacctttgt
    10141 taggagtacc gtcaagtgcg atcatagcac ggtcaatagc ttgttgatca cgtacatcgt
    10201 agccaatgat agcttcagca atgatgttgt ttacgttgtc aacagctttt tgtgtaccaa
    10261 gaccaccgta acgagatttg tcaccgtcgc gaagttcaac tgcttcgtgt tcaccagtag
    10321 aagctcctga tggaaccata ccacgtccga aagcacctga ttcagtgtaa acttctactt
    10381 caagtgttgg gttaccgcgt gagtctagga cttcgcgagc gtaaacatca gtaataattg
    10441 acatttttta ctctccttat gagttaaatt ttttacacct ctataatacc ttaaaacccc
    10501 tcctttttca agaaaaaacg ttatctttgt gcaacttttc cttaacttta taaagtaatc
    10561 gctttctttt gtctgtttta ttctaacttt tatgatatac tgttttcatg acagatttat
    10621 caaaacaatt acttgaaaaa gctcatggtg ggttaaaaat aaatccggat gagcaaagac
    10681 gctatcttgg tacttttgag gaaagagttc ttggatatgt agatattgac acagcaaata
    10741 gccctcagtt agaaaaaggc tttttattta ttttagaaaa ccttcaggaa aaagcagagc
    10801 cactatttgt gaagatttca ccaactatcg aatttgataa gcaagttttc tacttaaaag
    10861 aagcaaaaga aactgatagt caagccacca tagtatctga agagcatatt acttctcctt
    10921 ttggcctggt tattcatagc aatgcaccag ttcaagtaga agaaaaagac cttcgacttg
    10981 cttttccaaa actttgggaa gttaaaaagg aagaaccagc caaaacatcc ttatggaaga
    11041 aatggtttag ctaaatcttg cacatattta ataagtgccc aatattggca gccgtgcgct
    11101 ccagatagag actggcattt ttcaaactat cttctaaagg ttcacttttc tccaaaatag
    11161 aaaagacagc ttggatattt tcaaatggta ggggaggtaa atcttcagca agactaccgc
    11221 aaatagcaat aacaggaact ccaacagggg ttctttttgc aacacctata ggcgctttcc
    11281 cagcaaagct ttgactatca agtcttcctt ctccaacaac aaccaagtca gcatctgaaa
    11341 ctttcttatc aaagttgatt aagtccaagc aggtatcaat tccagacacg atacttgcct
    11401 gagcaaaagc acacaaacca ccagcaaggc ctccacctgc tcctgctcct ttaatttcta
    11461 atgttgcagg tgagaatttt tcataaaaat cttggatcgc ctgatctacg actgcaaaca
    11521 tagtcggatg tcgacctttt tgattgccaa aagtataagt cgcaccttga tgaccacata
    11581 agggacttac gacatctgct aaaatatgaa tttgaacacc ttcaggaatt ttatagcaat
    11641 tttctgttga aacagaagct aagtttaata aggattgacc ggaagcaggc aagacatttc
    11701 catccctatc ataaaattga taacctaaac cagcagcaat ccccagtcct ccatcattac
    11761 tggccgtgcc accaacatcg atataaatat ctttaatccc tttagaaatg agatggagaa
    11821 tcaactctcc aataccacaa gtttggattt gaagtggatt tcgtttctct agcggaattt
    11881 ttccaagacc aaccaagtca gctacttcaa atagtgccag ttcccctttt tgaaaatagc
    11941 gcatggcttc tttttgtcca aaagggtctg tcacttggat ccatttttct tttaggtcaa
    12001 gagaatgtcg gatagcatct acagtacctt ctcccccatc accaacaggg cagaggagac
    12061 attctacatc tgctatcgat tgttggaagc ctctttttat tgcttcagct acctgttgag
    12121 ctgtcaagct ttccttaaac gaatccggtg caattacaat cttcatattt tccctcattc
    12181 taaacagtca atcaaaggaa gaacttctaa aaaatccctc ttgtcaacat gatgtggtat
    12241 ttcttttttg agcatttctt tggaacaaaa ggcgattcct aactccgccg acttcaacat
    12301 taatagatta ttgcccccat caccgattgc caccgttctt tctttagaaa gttttagttt
    12361 ctttctccat ttttccagag tttctttttt gacctgggga cttataattt gtccaactaa
    12421 ttttcctgtt aaaagacctt ctttgacttc aagctggtta gcagtgaaat aggcaatacc
    12481 aagggatttt gctaatctct ccaactattg gtgtaaatcc accagacacc agaccaacta
    12541 ggataccatt cttttggaga atagagatga actctgggac atttagcgat agatgaattg
    12601 agttgaagac gttatcaaag accaaaatag gaagaccttc caacaaggac actctttttc
    12661 ttaaactgct ttcaaagacc aactctcctc gcattgctcg acttgtaatc tgcgaaattt
    12721 ctgcctcatg acctgcctct ctccctaaaa gatcaatcac ttcttctagg attaaggttc
    12781 catctacatc caaaacacac aagcctttta cttgagacat cagttctcct ctctaaacag
    12841 cctaaaaatc gtatgaagtc atcatacgat tttatctatt aattaactaa actatggtac
    12901 aagtcaaggt atgacttgca ggctgtatcc catgagaagt cactctccat agcttgtttt
    12961 tgtaggtttc tccaaatgtc tggatggttt ctatacaagt ccaatgctgt ttggaaagtc
    13021 caatttaacc aataaggaga tagattgtca aagctaaagc cagtaccgct tccttcgatt
    13081 ggattgaaag cgcgaactgt atctcgcaag cctccaactt catggaccaa tggcaaggtt
    13141 ccataacgca tagccatcat ttgagacaag ccacacggtt caaaacgact tggcatgagg
    13201 aagaggtcac aagcagcgta gatttcctga gcaagtttga catcaaaagt gatatttgtt
    13261 gatagcttgt ctgggtaaat ctgagcaaac catgagaaag ctccttcaaa ggctggatcg
    13321 ccagttccca aaagaacaat ctgaacatct tcttgcaaga tatggtgaag actttcgacc
    13381 accacatcaa aacctttttg acgtgtcaaa cgagaaacaa ttcccaccag tggaacgtct
    13441 gctctaacag gcaagccaac tctttcttgc aattttgcct tatttttggc tttcccagac
    13501 aaatcttcct gattgaaatg atagtctaaa agagcatccg tctgaggatt ataaagatca
    13561 gcatcaatcc cattcacgat accagatact ttaccagact ccattttaag aatctgatcc
    13621 aaattacatc caaactgact agtcataatt tcatgagcat agctaggtga aacggttgaa
    13681 acacggttcg catagagaat acctgccttc atccagttca gacagttgtt ccatcgaagg
    13741 gtgccatcag cgtaacgttc aaagccaact ccaaacaaat cacccaacat tccttctgaa
    13801 aattgtcctt ggaattctaa attatgaatg gttaaaactg tttcaatgtc ctcataggct
    13861 tgaatccaac ggtatttttc cttcaacaag aaaggaatca tagctgtatg gtagtcatga
    13921 acatggagaa gatcaggaat aaagtcaatc ctttccatag cctcaatggc agccagttgg
    13981 aaaaaggcaa agcgttctcc gtcatcaaaa tcaccgtaaa catgaccacg gaagaaataa
    14041 tattgattgt caataaagta gaaggttaca ccatttaata ctgttttctt aattccacaa
    14101 tactgtctgc gccaaccaac gctcacctca aaatgaagca catcttcaat ctgatttcca
    14161 aatttagcct ctaccatatc atagtagggt aaaatcactg caacttcgtg cccagctttt
    14221 accagtgatt ttggaagagc gccaatgacg tctcccaaac cacctgtttt tgaaaagggt
    14281 gcaccctctg ctgctacaaa taaaattttc atgaatgaat atcctctgtt actttagcac
    14341 ctttcttaac cacaactgga tgttctgcag ttcctcgaat cacaacacca ggctcaactt
    14401 caaccccttt gtccaagata gcatattcga cctgagcccc ttctccaata acaacacgag
    14461 ggaagagcag gctatcttta accaagctat ccttatggac atggatatta cgtgatagaa
    14521 cagaattagc tacttgacct tcaataatac taccagaggc aaactgagaa gttcttacct
    14581 tagatgtatt agcatagtaa gttggctctt cgtttttgac ctttgtataa atcttttggt
    14641 ttggtgagaa aagagaatag aatttttgtg attcaagcat atcgatattc gcttgataat
    14701 aagatttaac agagtgaata ttggctagat agcccgtgta ctcgtaggcg aaagctccct
    14761 cttttacagc caaatcccgt aaaacatagc gcaatttctc tggatgttct tttttagctt
    14821 cttcttccaa gtgttcaatc aaccaaggtg tatcaacgac aaagatatct gtagacatat
    14881 tgaacgtttc agctgttgac ttgctatcaa agagtttatg agaaagaaca tggtctgttt
    14941 catctacatc caagattgca tttacttctg aaatatcttt cttagctagt tttttataaa
    15001 ctacagtgat aggctctttt gttgtactat gtaggtggaa aacttggttc aaatcaatgt
    15061 taataagaac atcgcagttg agggcaaccg tttggtttga gccagaacgt ttcaaataag
    15121 taagaagctg ttggtagtat tcttttccaa ctgtactact ttctacacgg gtattgtaaa
    15181 ttcctagata gtaatggcta agaaaggttg ataagcccca ctcgcgtcct gaacgaatat
    15241 ggtcaaatac tgagctgata ttatcctgct ggaaaatacc aaagacacta cgaacacctg
    15301 cattagcaag gcttgaaagt gggaagtcaa tcaaacgata tttcccacca aatggcaaac
    15361 ttgctactgg acggtggtcc gtcaatgtcg acatattgtg aaaaccaact gtatttccta
    15421 aaatggcaga atatttatca atcttcatct gttgctaccc ccactacttc attatatcct
    15481 acaacttgta cttcatctgt tccatcaatt tcgacaccgt cagaaataat cgcaccttca
    15541 ccaataatgg cacgtttaat cttagctcct tgaccaatga tagctccact catgataact
    15601 gaatcaagga cttccgctcc ttcgcgaact tgcgcgcctg ttgaaaggat agaatgttta
    15661 acagttccat caacgaaaca tccgtctaca actaatgagt cttccacatg agcatttgcc
    15721 ccgaggaagt ttggtggtga aatcaagttt cttgagtaaa tcttccattg acggttacga
    15781 ctatccaagg cattttctgg agaaatatac tccatgttcg cttcccaaag tgactcaata
    15841 gtaccaacat ctttccaata accactaaat tcgtaagcat aaacactttc acctgactca
    15901 aggtaatttg gaatgacatt tttaccaaag tctgacatgc caaccttgct cttttcagca
    15961 gcgactaaca tattacgaag gcgttgccaa tcaaaaatgt agattcccat agaagctttt
    16021 gtagatttag gttgagctgg tttttcttca aattcaacaa tacgattgtt agcatctgtg
    16081 ttcatgatac caaaacggct tgcttcttta agagggacgt ctaaaactgc tactgtcaag
    16141 ctggcattat tatccttatg agactggagc atatcatcat agtccatttt gtagatgtga
    16201 tccccagaca aaatcaagac atactcagga ttgacactgt cgatatagtc gatattttgg
    16261 taaatagcgt gactagtccc ctcaaaccaa cgatttcctt cacttgcaga ataaggttga
    16321 agaatagaga cacctgaatt aataccgtct agtccccagc ttgaaccatt cccaatatgg
    16381 ttgttgagag caagtggttg atactgtgta acgaccccaa cattatgaat ccctgagttg
    16441 gcacagtttg atagggcaaa gtcaatgata cggtagcgcc caccaaattg cacagctggt
    16501 tttgcgatgc tttgagtgag tttaccgaga cgagttcctt gcccaccagc aagaatcaaa
    16561 gctaacattt catttttcat tttctactcc tttttggttt ttatttgtga cggttttagt
    16621 agatttcaag cgacgtttga ttttccatac acttgctccc atagccggta gggtaaaggt
    16681 taaggtctgc tcataatctt tccatagtcc ttcttgcgtt tgaacagttt gattatgttc
    16741 tttccaaacg cctccccact cttccaactc agtattccat acttcttcgt aaattcctgc
    16801 aacgggtagt ccgattgtaa aatctttccg ctcaacaggt accatgttaa agatacagac
    16861 taacatttct ccctttttac ccttacgaat aaaggaaaga acactctggt ctcgattatc
    16921 cgcatcaatg acttcaatac catcatagct ggtatcgatt tcccacagac agcgatgatc
    16981 tttgtaaaac tggtttagct gagaagtgaa atacttcatc ttagcattca ttgggtcttc
    17041 taggttagac cattccaact gttcttcaga tttccattct aggaattgac cgtattcgct
    17101 acccatgaag agcaatttct taccagggtg acaaatttgg tacgtataga gattgcgcaa
    17161 gcctgcgaat tgattgtaac gatctcccca catcttatgc atcatactct tcttgccatg
    17221 aaccacttca tcgtgcgaga atggcaagag ataattctcc ttgaaaacat acataaagct
    17281 gaaagtcacc aggttaaagt catatttacg ataaatcgga tcttcttcgt agaaacggag
    17341 gatatcattc atccagccca tgttccattt gtagtcaaat cctagaccac caatctcttt
    17401 cattcccgta atcttggttg cagacgaact ttcttctgca atcatcatca catctggata
    17461 ttctaactta ataacttcat tcaagcgttg aaggaaataa taaccttcat agttgagatt
    17521 tccgccatct ttattaggtg tccatggagc atcatcatag tccaaataga gcatgttgct
    17581 aacagcatcc acacgaatac catccaaatg atagatatca atccaatgct taatgcaaga
    17641 aattaagaag gactggactt cattttttcc aaggtcaaaa ttaagggcac cccaaccatg
    17701 gttatgagcc ttattatggt cttggtattc aaaagtcggt gtcccatcat aataggctaa
    17761 ggcatcatca ttgatggtaa agtgacctgg tacccagtcc acaataaccc caatattatg
    17821 ggtatgacac tcctcgacaa aatcttgaaa ctcctctggt ctaccatagg catgctctaa
    17881 agcgaagtaa cccataagct ggtaccccca actcaaacct agtgggtggg acatcaaggg
    17941 cataaactca atatgagtat agttcatctc aactaggtaa ggaatgagtt catctttcaa
    18001 ttgggcaaaa ctataaggac tgccatcagg atttctcttc caagagccag catgaacctc
    18061 gtaaatattg acaggacgtt cagcaaagcc ccaacgtttt cttcgtgcca gccaaagtcc
    18121 atccctccat ttcttatcag gaagctctgt tacgattgcc cctgttcctg gacgagcctc
    18181 atacctgaca gcaaaagggt caatcttcat cagttgatga ccattttgac gtgtgacatg
    18241 atatttgtaa atatgccctt cttgagccat attggtaaag acttcccaga ccccaaagtc
    18301 atttcttacc attggaatct gattttcaat ccaattggta aaatcaccaa ccaagtgaac
    18361 agcctgagca ttaggtgccc aaacacggaa ggtatagcca tactctccat ttagttcttc
    18421 cctatgtgct cctagataat gttggagata aaaattttca cccgtcataa aggtttttaa
    18481 tgcttctcta ttatccatat actccctttc tcctgtaagc gttttctatg tttttattat
    18541 actacctttt tagagaagat tcaagtaaat tactatactt ctttaattat tttgaaaatc
    18601 tacaacaagt tcacttactc gttcaattgt aaatcaatat tttttcaaaa aattgcgaaa
    18661 acacctttct ttttctacta tagtgaaatg aaataaaaca tgcgcaaatc gattaaggaa
    18721 tttaatctaa tttctaacaa tgtcttagaa at
//
LOCUS       DAVBCA010000045        17859 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.045, whole genome shotgun sequence.
ACCESSION   DAVBCA010000045 DAVBCA010000000
VERSION     DAVBCA010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17859)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17859)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17859
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.045"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..215)
                     /locus_tag="VQU19_001492"
     CDS             complement(<1..215)
                     /locus_tag="VQU19_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2480725.1"
                     /translation="MEQLHFITKLLDIKDPNIKILDIINMDTHKEIIAKLDYEAPSCP
                     DCGSLMKKKEPEKFFGLIEDNLKQVHP"
     gene            complement(466..1401)
                     /locus_tag="VQU19_001493"
     CDS             complement(466..1401)
                     /locus_tag="VQU19_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HET2480726.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTAIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(1398..2258)
                     /locus_tag="VQU19_001494"
     CDS             complement(1398..2258)
                     /locus_tag="VQU19_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HET2480727.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFYYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKSPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            2366..4528
                     /locus_tag="VQU19_001495"
     CDS             2366..4528
                     /locus_tag="VQU19_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HET2480728.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHSVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATITSYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIATLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIILSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPDYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHEIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMIRYFPQVWASDNTDAIARLPIQYGSSYFYPTISMGA
                     HVSAVPNHQMGRMTPLETRGHVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTASNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            4620..5879
                     /locus_tag="VQU19_001496"
     CDS             4620..5879
                     /locus_tag="VQU19_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET2480729.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADDTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRSE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            5893..6759
                     /locus_tag="VQU19_001497"
     CDS             5893..6759
                     /locus_tag="VQU19_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2480730.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSIVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFFLIVVIS
                     IIQLRVSKKFEI"
     gene            6773..7606
                     /locus_tag="VQU19_001498"
     CDS             6773..7606
                     /locus_tag="VQU19_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET2480731.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKSTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIIAGISNGAV
                     K"
     gene            7607..7687
                     /locus_tag="VQU19_001499"
                     /pseudo
     CDS             7607..7687
                     /locus_tag="VQU19_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            7825..9267
                     /gene="gtfA"
                     /locus_tag="VQU19_001500"
     CDS             7825..9267
                     /gene="gtfA"
                     /locus_tag="VQU19_001500"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HET2480732.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGEKYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKDLFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTEILPEIHEHYSIQFKIADHDYYVYDFTLPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAREVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVAEIDLQNQTYRVIENGVEVSF"
     gene            9405..10598
                     /locus_tag="VQU19_001501"
     CDS             9405..10598
                     /locus_tag="VQU19_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HET2480733.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            11285..13264
                     /locus_tag="VQU19_001502"
     CDS             11285..13264
                     /locus_tag="VQU19_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2480734.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAAKETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KVVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            13331..14827
                     /locus_tag="VQU19_001503"
     CDS             13331..14827
                     /locus_tag="VQU19_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2480735.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGALTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPGTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            14827..15753
                     /locus_tag="VQU19_001504"
     CDS             14827..15753
                     /locus_tag="VQU19_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2480736.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSIRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            15762..16829
                     /locus_tag="VQU19_001505"
     CDS             15762..16829
                     /locus_tag="VQU19_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2480737.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            16840..17766
                     /locus_tag="VQU19_001506"
     CDS             16840..17766
                     /locus_tag="VQU19_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2480738.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQAELARYQKGLN"
BASE COUNT         5251 a         3187 c         3724 g         5697 t
ORIGIN      
        1 ataggatgaa cctgcttaag attgtcctca ataagtccga aaaatttctc tggttccttt
       61 ttcttcatta gacttccaca atcagggcaa gatggagcct cataatccag cttagcgata
      121 atttctttgt gggtatccat attgatgata tctagaatct tgatgtttgg gtctttaatg
      181 tctagtaatt ttgtgataaa atgtaattgt tccatatgat tctttctaat gagttgtttt
      241 gtcgcttttc attataggtc atatgggact ttttttctac acaaaatagg ctccataata
      301 tccataggga atttacccac tacaaatatt atagagcccg ttttaatgag agtttgtaac
      361 tctctttttt gtttttagag acaataaaac ttcagatccg taaaacttaa ttgaattact
      421 aatctgaagt tatttttata tcgtttatat tataattgtg ttattttact tccaactatt
      481 gagagaaatt tcgccactat ttagccagat ttcttttccg ttatcacatt gaactaaaag
      541 ttttccattt tctgagatgt ctttagcaag tcccttgtag tctttttgct ctagtgtgaa
      601 agtgacttct tttcctagaa tgaatgactg ttttttgtat aggtataata gctcttctgc
      661 tggtgtttcg aagaaagcac gccagatttc tatgatcaat tcattccttg ttataggagc
      721 tgtagcttta aataagctgg cagctttttc ttttaattcc tgagggaagt ctttaatagt
      781 gaaattgata cctactccaa taatgatatc tgtgactaag ccagtttcta cagaggtcat
      841 tgcttcagta aggattcctc caattttatg attgtttaga tagatatcat tgacccattt
      901 tatgtcgaca tctattaaag ttaggttctt aatggctttg tagacagctc cagctacaag
      961 tagtgtgtag gatggtaatt tgtcataggg gagatttggt ttaagatgga gtgtcatata
     1021 aataccacct tgtggtgagt agaaggaacg ttgaaaacgg cctcggcctg ctgtttgata
     1081 ggaagctaga tagagggtat ttgcttcatg gcctaaatca attgcttctt ttgcatctag
     1141 ttgtgttgat tttgtttcgg gtttaaagct gactttaatt ggaagatttt cttctagaat
     1201 ctctggaaga ataaggtcac cattcatcag tttatatcct ctatttttga tactatcaat
     1261 ttcaatgcct tcttgttcta gtcgcttgat ggctttccaa attgctgttc ggcttaggga
     1321 tagtttttct gcgatttttt ctccgctgat atagtcggtt tctttagata ggatttggta
     1381 gacagcttgg taggatttca taatgttgcc tttctcacta gttggtattg agagtattct
     1441 tttcttgtat gacttggagt ctgattaaag tattgtttat aagctttcga aaaatggagt
     1501 ggatctgaaa aacctaccga gtatgcaatt accttgatgg actcttgggt attttcgaga
     1561 agttgtctag ctcggtgcat tcgaacgtag agtaggtatt ctttgggtga taaggtatta
     1621 aattctttga atacgcttga taagtagctt ctgtgaacgg atagttcttt tgctaaatct
     1681 tgaattgtaa gtgattgagg atagtggcta tcaattaatc gtttgcattc aagatagagt
     1741 tggtgggttg atgaaatatt cttttttttc tgattgggag caatagttcc cagatgaaac
     1801 atcagttcat gaagttgtcc catgatatgg agttgagcta attcacttga ttttgtaatc
     1861 tgagcgaagc ggacaatgtc tgagatgagt tttgcagtag tctgggtatg acaagtttca
     1921 gattggatga gataggattg atcagaaatt tgagaaagag caaaataatc aggggatttc
     1981 cctccagtga ttcctaacca gtagtaggcc caaggttctt tactatctgc ttgataaaag
     2041 gttagttcct ctggttttaa tagaaagaaa tctccttctt ttaaatcaac aattttaccc
     2101 ttgtaataaa attttccttg tcctttagta atgtaatgta gaacgtatgt atcacgaatg
     2161 gctggaccaa aagagtaatt aggtgtgcat tcctcatatc cataaaagct tagggcaagg
     2221 tcgattgttc cagtctggta ttctgaaaaa actaacatgt gctacctcct acctaacatt
     2281 ttaccatatt cttgagacat ttttctattt tggaaagcga tttcaggtga taaaatataa
     2341 tcaataaagt gatgaggtga agtaaatggg agttaggata gagaataatc tattttatgt
     2401 tgagagtaaa aatctaagtt tgattattga aaatcgaaat ggctacttac ttttgaaaca
     2461 tttaggaaag actattaaga actataaagg ttccaatagt gtttatgaac gagaccatgc
     2521 cttttcagga aatccaacgg ctactaatcg aacctttagt ttagatactc agcgacagat
     2581 ttttggacaa catggcttag gagattttag gaaaccaact atacaggttc agcatagtgt
     2641 aactgaagta acagactttc gatttgtaga agcaaagatt ttaaaaggtc agaatggtcc
     2701 acagggctta ccttctccac atagcatgga cgatacagag actcttgtct taatgttaga
     2761 agattctaag gctcaactta gtctgacttt gtattatact acttttaata atgatgcgac
     2821 tattactagc tacagtaaat tagataataa tagtaatcag gaagttgtca tccataaaga
     2881 tttttctttt atggctgatt ttccagctgc agattacgaa atagcaactc tgcagggtgc
     2941 ttatgctcgt gaaaagactg ttagacgtca acaggtagaa caaggaatct tttcgattag
     3001 ttcaaaccga ggtgcttctg gtcatgctca aacaccagct cttctactat gcgaacaagg
     3061 agtcacagag gatgctggga atgtgtttgc tattcaacta atgtatagtg gcaactttga
     3121 agcttttgtt caaaaaaatc aattgaatga agttcgggtg gctattggca ttaatccaga
     3181 aaacttttct tggaagttag cccctgagga atactttgaa acaccggtag ctttagtgac
     3241 tcattcagat cagggattaa ctggtattag tcatgaaagt cagaattttg tactgaagca
     3301 cattattcta agtgaatttt ctaaaaaaga acgtccaatt ctaatcaata actgggaagc
     3361 tacttacttt gactttcaga gagaaaaact gttagagtta gcagatgaag ctaagaaagt
     3421 tggcattgaa ctttttgtat tagatgatgg ttggtttggc aatcgttttg atgataatcg
     3481 tgctttaggt gattgggttg ttaatgagga aaaactgggt ggaagtctag aaagtctgat
     3541 ttcagctatc catgaaagag gtttgcagtt tggactttgg ttagaacccg aaatgatttc
     3601 tgtagatagt gatttgtatc gtcaacaccc tgactgggct attcaggttc ctgactatga
     3661 gcatacttat tctcggaatc aattagtact taatcttgcc aatcctcagg tagtagaata
     3721 cttgaaaagt gtcttagatc aactcctatc ttatcatgag attgattaca ttaaatggga
     3781 tatgaaccgc aatatcacta agctagggaa tggattaact tatctagaga cacagatgca
     3841 atctcatcag tacatgctgg ggctttatga actcgtttct tatctgacag agaagcacag
     3901 ccatattctc tttgagtcct gctctggtgg tggtggacga aatgatcttg gtatgatacg
     3961 ctatttccca caagtctggg ctagtgataa tactgatgcc attgcacgtt taccaattca
     4021 atacggttca tcctatttct atccaaccat ttctatgggg gctcatgtgt cagcagtacc
     4081 gaatcatcag atgggacgaa tgacaccatt agaaacacgt ggccatgtag caatgatggg
     4141 aaatttgggc tatgagcttg atttgacaaa tttatcagat gaagagaaag ctacgattgc
     4201 taatcaggtg aacttgtata aagaattacg accagtagtt cagttaggac agcagtatag
     4261 actaattaat cctgatactg catccaatga agcagctgta caatttaatt acggaaatca
     4321 aacgattgta acctacgttc gcgttttatc tgttgtagag accatggaaa caactttaaa
     4381 attaaaagat ttggatgaag agggactata taaattacag gaaaatggcg aagtttactc
     4441 aggtgcagaa ctaatgtatg cgggcttaac tgttatctta tcccaaggag attttttgag
     4501 tagacagtat atttttagaa aactatgata tgtactgacc ccaaaagtta gatttattct
     4561 atctaacttt tgaagtgcag tttgataagg gtgtataaat ttataaagga ggctttctaa
     4621 tggaatggta taaaaaaatc ggacttcttg caactacagg tttagctttg tttgggctcg
     4681 gtgcttgctc caactatggt aaatctgcgg atgacacagt gaccatcgag tatttcaacc
     4741 agaaaaaaga aatgaccaaa accttggaag aaatcactcg tgattttgag aaggaaaacc
     4801 ctaagataaa ggtcaaagtc gtcaatgtac caaatgctgg tgaagtattg aagacacgcg
     4861 ttctcgcagg agatgtgcct gatgtggtca atatttaccc acagtccatc gaactgcaag
     4921 aatgggcaaa agcaggtgtc tttgaagatt tgagtaacaa agactacctg aaacgcgtga
     4981 aaaatggcta cgctgaaaaa tatgctgtaa acgaaaaagt ttacaacgtt ccttttacag
     5041 ctaatgctta tggaatttac tacaacaaag ataaattcga agaactgggc ttgaaggttc
     5101 ctgaaacctg ggatgaattt gaacagttag tcaaagatat cgttgctaaa ggacaaacac
     5161 catttggaat tgcaggtgca gatgcttgga cactcaatgg ttacaatcaa ttagcctttg
     5221 cgacagcaac aggtggagga aaagaagcaa atcaatacct tcgttattct caaccaaatg
     5281 ctattaaatt gtcggatccg attatgaaag atgatatcaa ggtcatggac atccttcgca
     5341 ttaatggctc taagcaaaag aactgggaag gtgctggcta taccgatgtt atcggagcct
     5401 tcgcacgtgg ggatgtcctc atgacaccaa atgggtcttg ggcgatcaca gcgattaatg
     5461 aacaaaaacc gaactttaag attggaacct tcatgattcc aggaaaagaa aaaggacaaa
     5521 gcttaaccgt tggtgcggga gacttggcat ggtctatctc agccaccacc aaacatccaa
     5581 aagaagccaa tgcctttgtg gaatatatga cccgttcaga agtcatgcaa aaatactacg
     5641 atgtggacgg atctccaaca gcgatcgaag gggtcaaaca agcaggagaa gattcaccgc
     5701 ttgctggtat gaccgaatat gcctttacgg atcgtcactt ggtctggttg caacaatact
     5761 ggaccagtga agcagacttc cataccttga ccatgaacta tgtcttgacc ggtgataaac
     5821 aaggcatggt caatgatttg aatgccttct ttaacccgat gaaagcggat gtggattagg
     5881 agtagagaga ctatgaaaaa agtattacaa aaatattggg catgggcttt tgtggtcatc
     5941 cccctcttgt tacaagcaat tttcttctat gtgccgatgt ttcaaggagc cttttacagt
     6001 tttaccaact ggacaggatt gacttacaac tacaaatttg tcggcttaaa caactttaag
     6061 ctcctcttca tggatccaaa attcatgaat gcgattggct ttaccgcaat cattacgatt
     6121 gccatggtgg ttggtgagat tgcactcggg atcttcattg cgcgtgtctt gaactctaaa
     6181 atcaaaggcc aaaccttctt ccgtgcttgg ttcttcttcc cagctgtttt atctggtttg
     6241 acagtggctt tgatcttcaa gcaagtcttc aactacggtc ttccagcgat tgggaatgcc
     6301 cttcatattg aatttctcca aaccagtctt ttagggacta agtggggagc aatctttgcg
     6361 gctgtctttg tccttctttg gcaaggggtg gctatgccca tcatcatctt cctagctggt
     6421 ttgcaatcta ttccaactga gattacagag gcagcaagga ttgatggtgc gactagcaag
     6481 caagttttct ggaacattga attgccttac ttgctaccaa gtgtctctat agtctttatc
     6541 ctagccctaa aaggtgggct gactgccttt gaccaagtct ttgccatgac cggtggtggt
     6601 ccaaacaatg ccacaacctc acttgggctc ttggtttata actatgcctt taaaaacaac
     6661 caattcggtt atgccaatgc cattgccgta atcttgttct tcttaattgt agtgatttcg
     6721 atcatccaat tgagagtatc taagaaattt gaaatttaag aggagaagca tgatgaaaca
     6781 agatgaaaga aaagccctga ttggcaaata cattctattg attctaggat cggttctgat
     6841 tttagtgccg ctccttgcta ccctctttag ttccttcaaa tccactaagg atattgtaga
     6901 taatttcttt ggctttccaa ccaacttcac atgggacaac tttagccgtc tcttagctga
     6961 tgggattgga ggctattatt ggaactctgt cgtcatcact gtcttgtctt tacttgcagt
     7021 aatgatcttt atccctatgg cagcctactc catcgctcgc aatatgagta aaagaaaagc
     7081 ctttaccatc atgtataccc tcttaatcct cggaatcttc gtacctttcc aagtcatcat
     7141 gattccgatt acggttatga tgagtaaact cggtttggct aatacctttg gtttgatctt
     7201 gctctacttg acctatgcga ttccacagac cctctttctc tatgttggct atatcaaaat
     7261 ctcgattcca gaaagtctgg atgaagcagc agagatcgat ggggctaatc aatttacaac
     7321 ctatttccgc atcatcttcc caatgatgaa accgatgcat gcgacaacca tgatcatcaa
     7381 tgccctttgg ttctggaatg acttcatgtt gccactcctt gtcttgaacc gggattccaa
     7441 aatgtggact ctgcctttgt tccaatacaa ctacgcaggc caatatttca acgactacgg
     7501 accaagcttt gcctcttacg tggtcggcat tatcagtatc accattgtct atctcttctt
     7561 ccaacgccat atcatcgcag gaataagcaa cggggcagtg aagtaatact caatgaaaat
     7621 caaagagcaa actaggaagc tagccgcagg ttgctcaaaa cactgttttg aggttgtgga
     7681 tgaaactgac gaagtcagta accatatcta cggtaaggcg acactgacgt ggtttgaaga
     7741 gattttcgaa gagtataaca tgaatttgat ttacgaagcc agatcatatg agacttggct
     7801 tcaattagaa aaaggagagt aatgatgcca attcaaaata aaaccatgtt gattacctat
     7861 tctgatagcc ttggaaataa tcttaaagac ttatatgata atttggaaga gcattttgga
     7921 gatgctattg gaggagttca ccttttacca tttttcccat caacaggtga tcgtggattt
     7981 gcgccagttg actacgacga agtggactca gcttttggtg attgggagga tgttaagcgt
     8041 ttaggtgaga aatattatct tatgtttgat tttatgatta atcatatttc tcgtcaatcc
     8101 aagtattata aggactatca agaaaaacat gaagccagtg aatttaaaga tctcttttta
     8161 aactgggata agttttggcc agaaaaccgt ccgacacagt ctgatgtaga tttaatttac
     8221 aagcgtaagg atcgtgcacc aaagcaagag attgtgtttg aagatggttc agtggaacat
     8281 ttgtggaata cctttggtga ggagcagatt gatcttgatg tgaccaaaga agtaactatg
     8341 gaatttatcc gtaagaccat tcagcacttg gcaagtaatg ggtgtgattt gattcgtcta
     8401 gatgcctttg cttatgcagt gaagaaattg gatactaatg atttctttgt ggaaccagat
     8461 atttgggatt tattggacaa agttcgagat atcgctgctg agtatgggac agagatttta
     8521 cctgagattc atgaacacta ttcgattcag tttaaaatag cagaccatga ttactatgtt
     8581 tatgatttta ctcttccaat ggtgacactt tatactcttt acagttccag aacagagcgt
     8641 ttggctaagt ggttgaagat gagcccgatg aagcaattta cgacgctaga tacccatgat
     8701 gggattggag tagtagatgt caaggatatc ctgaccgatg aggagattga ctatgcttca
     8761 aatgaactct ataaggttgg agccaatgtc aaacgtaagt actctagtgc cgagtataac
     8821 aacttagata tctaccaaat caattcaacc tactattcag cgcttggaga tgatgatgtc
     8881 aagtattttc tcgctcgtct aattcaagct tttgccccag gtattcctca ggtttactat
     8941 gtgggtctat tagcaggcaa gaatgacttg aaattattag aagaaactaa agaaggtcga
     9001 aatattaatc gtcattacta tagcaacgag gaaatagcaa gagaagtgca acgacctgtt
     9061 gtgaaggccc ttctcaatct attttctttc cgtaaccgtt cagaagcctt tgatctagaa
     9121 gggactactg agatagagac accaacagct cacagcattg taatcaaacg tcaaaataaa
     9181 gataagtccg taacagcagt agcagaaatt gatttgcaaa atcagactta tcgggtaatt
     9241 gagaatggag ttgaagtatc attttgaagc cttgatatgg tggataaaat agggttttta
     9301 ttttggaaaa cgtttccttt gttttcaaat tgctaaaaaa gtggtacaat ataggatagc
     9361 ttactattat ctgaatcagc tgatttggag agaaaggatt cattttgaaa tcaataggct
     9421 ttattgaaaa gctgaagggg ttgtctagta aagagctgat tttattggga attatcctaa
     9481 gtatcttttt acccttttat ctttttgtag ttgtactctg tttatatatt atcagtttga
     9541 tttttacagg agacatgaaa agtattcttc agaaaatggg ggagcatccg atgctgcttc
     9601 tttttcttag ctatagtact gttatatcca ttcttgcaca aaattggatg ggtcttgtgg
     9661 cttcagtagg aatgtttcta tttactattt tctttttgca ctatcagtcg attttatccc
     9721 ataaattctt tcgattgatt ttgcagttcg tcttgtttgg tagtgtcttg tcagctgctt
     9781 ttgccagttt agaacatttc caaattgtga agaaatttaa ctatgctttt ctttcaccca
     9841 atatgcaggt gtggcatcag aaccgggcag aagtgacctt ctttaatcct aattattatg
     9901 gaattatttg ttgtttctgt attatgattg ctttctatct gtttacaacg accaagttga
     9961 attggttgaa agtattctgt gtgattgcag gctttgttaa tctctttggt ttgaacttta
    10021 ctcaaaatcg aactgccttt cctgctatta tcgctggagc aattatctat ctctttacga
    10081 ctattaaaaa ctggaaggcc ttttggctta gtattggggt cttcgcgatt ggtttgagtt
    10141 tcctcttttc tagtgatttg ggagttcgaa tgggtacttt agactcttct atggaagaac
    10201 gcatttctat ctgggatgct gggatggcct tgtttaagca aaatcctttt tggggtgaag
    10261 ggccattgac ctatatgcac tcttatcctc ggatacatgc tccttatcat gaacatgccc
    10321 acagtcttta tattgatacg attctgagtt acggaattgt gggtaccatt ttattagttt
    10381 tgtcttctgt tgctcctgtt cgcttgatga tggatatgag tcaggagtcg gggaaacgtc
    10441 cgattatcgg cctttatcta tctttcctta cagtggttgc tgtgcacgga atttttgact
    10501 tggctctctt ctggattcag tcaggcttta ttttcttgct agttatgtgc agtattccat
    10561 tggagcatcg aatgttggta tcggacatga cggattaagt tttataagtt tgaaatcttc
    10621 taccttgggt aggagatttt tttatacgat gggcatgtcg tgcatctgag gtgtaagtcc
    10681 tctgtaggga tccactaccg gtgaatacaa tagcgctccc caagcctgac tatcgtgagg
    10741 tagcggatta aaatggtctg gggatagatc gttttaagtc tgacgcagga aataagaatt
    10801 gtcagagaaa gcaatagtga aatcgtaggc tatgaataga aacgtgatag cgaggagcat
    10861 atagtggata aggtagcgag aaattttaaa gtataaaaga tagtcttaat ctatatatgt
    10921 aaatcacaaa agtaattgaa ttcggaataa ggttggtgtg aaaagacata gtaaactgaa
    10981 tcttgaatac tagaatgata cttctacaat attgttataa tttaatttga attccaaaat
    11041 cacattgttc cgtccgtatt tcattttact gtatgtcttc ctaaactcca aagtttctgc
    11101 gtcaaatttc ctattttcac tgtagtcttt gacacttcga acgacaattt gaatcatata
    11161 ttcaaaaaaa aatgaaaaat ttgtgccaac aagcctaaat attctgaaaa tttgtttgat
    11221 ttttaatgga taatgtgata taatggttgt caatctataa ttcacataaa cagaggagta
    11281 gaaaatgaaa aaaaatcgtg tatttgctac agcaggtctt gttttattag cagcaggtgt
    11341 acttgcagca tgcagttctt caaaatcatc tgattcatca gcccctaaag cttatggcta
    11401 tgtttataca gcagacccag aaaccttgga ctacctgatt tcaagtaaaa atagtacaac
    11461 agtagtgact tcaaatggga ttgatggttt attcactaac gataattacg gtaatcttgc
    11521 tcctgcagtt gcagaggatt gggaagtctc taaggatggt ttgacctaca cttataagat
    11581 tcgtaaaggg gttaaatggt ttacctctga tggagaagaa tatgcagagg tgacggctaa
    11641 agatttcgtg aacggtttaa aacacgcagc agataaaaaa tcagaagcta tgtatttagc
    11701 tgaaaattcg gttaaaggct tggcagatta tctatcagga acttcaacag atttttcaac
    11761 agttggtgtc aaggcggttg atgattatac gttacaatac actttgaacc agcctgaacc
    11821 gttctggaac tctaagttga cctattctat tttctggcct ctgaatgaag aattcgaaac
    11881 atcaaaagga agcgattttg ctaaaccaac agatccgaca tccttgcttt ataatggtcc
    11941 attcttgttg aaagggttga ctgcaaaatc ttctgtagag tttgtaaaaa atgagcaata
    12001 ttgggataaa gaaaatgtcc acctagatac tatcaatcta gcttactatg atggatcaga
    12061 tcaggagtcg ctagagcgta acttcactag tggagcttat agttatgccc gtctttaccc
    12121 taccagctcc aactattcta aggttgcaga agaatacaag gacaatatct attacacaca
    12181 atcaggctct gggattgctg gtctgggtgt gaatattgat cgccaaagtt acaactatac
    12241 ttctaaaact acagattcag agaaagtagc tactaagaag gcattgctta acaaagattt
    12301 ccgtcaagcc ttgaattttg ctcttgatcg ctcagcttac tcagctcaaa tcaatggtaa
    12361 agatggagca gctttagcag ttcgtaattt atttgtaaaa ccagactttg tttcagctgg
    12421 tgagaagacc tttggtgatt tagtcgctgc tcaacttcct gcttatggtg atgagtggaa
    12481 aggtgtgaat ttagctgatg ggcaggatgg tttattcaat gctgacaagg ccaaggcaga
    12541 gtttgcgaaa gctaagaaag ctttagaagc agacggcgtt cagtttccta ttcatctgga
    12601 cgttccagta gaccaagcat caaaaaacta catatctcgt attcagtcct ttaaacaatc
    12661 tgtagaaaca gttcttggtg ttgaaaatgt cgttgttgat attcaacaaa tgacaagtga
    12721 tgaattcctt aatattactt actatgctgc caatgcttca tctgaggatt gggatgtatc
    12781 gggaggagtt tcatgggggc cagactatca agacccatct acttacctgg atattttaaa
    12841 aacaactagc agtgaaacta caaaaacata tttaggattt gataatccaa atagcccttc
    12901 agtagttcaa gttggtttga aagaatacga taaattagtt gatgaagctg ccaaagagac
    12961 aagcgacttg aatgtccgtt atgaaaaata tgcagcggct caagcatggt tgacagatag
    13021 ttcactcttt attcctgcta tggcttcttc tggtgcagca ccagtgcttt cacgaattgt
    13081 tccatttact ggagcttctg cgcaaacagg ctctaagggg tcagatgttt acttcaaata
    13141 tttgaaatta caagataaag tggtgactaa ggaagagtat gaaaaagctc gtgaaaaatg
    13201 gttgaaagaa aaagctgaat caaatgagaa agctcaaaaa gaattggcaa gtcatgtgaa
    13261 gtaaataatt tctaatagaa ctttctctcc atgaggagaa ggttcttttg ggatttttaa
    13321 aggaaataat atgaaaaaat atatttttat gcgtgttttg cggtcattgg tttcgatttt
    13381 cttagtaacg actttgacct acacgattat ctataccttg gttcctcgaa aattgatttt
    13441 caagcaggat cctaactata ataaaattgc aacaacggct gataaacgtg ataactatga
    13501 aaatactgtg tttgagcgta tgggctacat tgagtattac gatactaaag agttgcaaga
    13561 aaaggcaagt agcatggatt cttctgtaac agtagaagca aatgcgacca ataaagctat
    13621 ttatgaaaag tacatcaatc aattaggtca tggttggact ttgggagaat ttactgaaag
    13681 tggtcaattc tatgctactc gtgaaattcc aatttttgaa cgtgtttttc acttctatgc
    13741 taacttgatt gacattgacc atacaaataa aatccaagac cctgaaaatc cagacttgaa
    13801 acgctacctt cgttttgaaa atgatccagc tatcggatgg tcattggtcg gttcaggaac
    13861 taaacataaa tatctcttgt actttaacag tcagttccca tttgttcatc aaaactttgt
    13921 gaacttgaat ttaggtgact cttacccaac ctatgctaat acaccagttc ttcaggttat
    13981 tactcaaggt caaggacaaa ccaaaactgc ccaagttcag ttcccaacag gtaagaaaac
    14041 gtcttctgta aatatttact caagaaccta caagtcacct agtcaggctg actctcgtga
    14101 agtagctagc tatgggaaag atgatcctta tacagcgact gaaagtaatt accaatatcc
    14161 atctatgatt gtcagctctg ctattactgg tttgattggt ttggttcttg cctatgctct
    14221 tgccgtgcca cttggttcag ccatggctcg tttcaagaac acttggattg atagcctctc
    14281 aacaggggct ttgaccttct tgcttgctct tccaacgatt gccttggttt acatcgttcg
    14341 attgattgga tcatctattg cccttccaga ttcattccct atcttgggag ctggagattg
    14401 gcgttcttac gttttaccag cagtcatcct tggtttgttg ggtgctcctg gtacagccat
    14461 ttggattcgt cgttacatga ttgacttgca atctcaagac tttgttcgtt tcgctcgtgc
    14521 aaaaggtttg tctgaaaaag aaatttcaaa caaacacatc tttaaaaatg ccatggttcc
    14581 gctggtttca ggaattcctg gtgccatcat tggggttatc ggtggtgcaa cccttactga
    14641 aacagtcttc gccttcccag gtatgggtaa aatgttgatt gactctgtaa aagcatctaa
    14701 taactctatg gtcgttggtc ttgtcttcat ctttacatgt atttctatct tctcacgtct
    14761 tttgggagat atttggatga ctattattga cccacgtatt aaattgactg agaaaggagg
    14821 caaataatgt ctacaatcga taaagaaaaa tttcagtttg taaaacgtga cgattttgcc
    14881 tctgaaacta ttgatgcgcc agcatattct tactggaaat cagtgtttaa acaatttatg
    14941 aagaaaaaat caactgtagt catgttggga atcttggtag ccatcatttt gataagtttc
    15001 atctacccaa tgttttctaa gtttgatttc aatgatgtca gcaaggtaaa cgactttagt
    15061 attcgttata tcaagccaaa tgcggagcat tggttcggta ctgacagtaa cggtaaatcg
    15121 ctctttgacg gtgtctggtt cggagctcgt aactccatcc tcatttctgt gattgcgaca
    15181 gtgattaact tggttatcgg tgtttttgtc ggtggtattt ggggtatttc aaaatcagtt
    15241 gaccgtgtca tgatggaagt ttacaacgtc atctcaaaca tcccacctct tttgattgtt
    15301 attgtcttga cttactcaat cggagctgga ttctggaatc tgatttttgc catgagcgta
    15361 acaacatgga ttggtatcgc cttcatgatc cgtgtgcaaa tcttgcgcta tcgtgacttg
    15421 gaatacaact tggcatcacg tactttggga acaccaacct tgaagattgt tgccaaaaat
    15481 atcatgcctc aattggtatc tgttattgtg acaaccatga ctcaaatgct tccaagcttt
    15541 atctcatacg aagccttctt gtctttcttc ggtcttggat taccgattac agtgccaagt
    15601 ttgggtcgtt tgatttcgga ttattcacaa aacgtaacaa ccaatgctta cttgttctgg
    15661 attccattga caacccttgt cttggtatcc ttgtcccttt tcgtagttgg tcaaaactta
    15721 gcggatgcta gtgatccacg tacacataga taggagtaga aatgacaaaa gaaaaaaatg
    15781 taattttgac tgctcgcgat attgtcgtgg aatttgacgt tcgtgacaaa gtattgacag
    15841 ccattcgcgg cgtttccctt gaactcgttg aaggagaagt attagccttg gtaggtgagt
    15901 caggatcagg taaatctgtt ttgacaaaga ccttcacagg tatgctcgaa gaaaatggtc
    15961 gcattgccca aggtagtatt gactaccgtg gtcaggattt gacagcttta tcttctcaca
    16021 aggattggga acaaattcgt ggtgctaaga ttgcgactat cttccaggac ccaatgacta
    16081 gtttggaccc cattaaaaca attggtagtc agattacaga agttattgta aaacaccaag
    16141 gaaaaacagc taaagaagcg aaagaattgg ccattgacta catgaataag gttggcattc
    16201 cagacgcaga tagacgtttt aatgaatacc cattccaata ttctggagga atgcgtcaac
    16261 gtatcgttat tgctattgcc cttgcctgcc gacctgatgt cttgatctgt gatgagccaa
    16321 caactgcctt ggatgtaact attcaagctc agattattga tttgctaaaa tctttacaaa
    16381 acgagtatca tttcacaaca atctttatta cccacgacct tggtgtggtg gcaagtattg
    16441 cggataaggt agcggttatg tatgcaggag aaatcgttga gtatggaacg gttgaggaag
    16501 tcttctatga ccctcgccat ccatatacat ggagtctctt gtctagcttg cctcagcttg
    16561 ctgatgataa aggggatctt tactcaatcc caggaacacc tccgtcactt tatactgacc
    16621 tgaaagggga tgcttttgcc ttgcgttctg actacgcaat gcagattgac ttcgaacaaa
    16681 aagctcctca attctcagta tcagagacac attgggctaa aacttggctt cttcatgagg
    16741 atgctccaaa agtagaaaaa ccagctgtga ttgcaaatct ccatgataag attcgtgaaa
    16801 aaatgggatt tgcccatctg gctgactagg aggaaggaaa tgtctgaaaa attagtagaa
    16861 atcaaagatt tagaaatttc cttcggtgaa ggaagtaaga agtttgtcgc ggttaaaaat
    16921 gctaacttct ttatcaacaa gggagaaact ttctcgcttg taggtgagtc cggtagtggg
    16981 aaaacaacta ttggtcgtgc tatcatcggt ctaaatgata caagtaatgg agatatcatt
    17041 tttgatggtc aaaagattaa tggtaagaaa tcgcgtgaac aagctgcgga attgattcgt
    17101 cgaatccaga tgattttcca agaccctgct gcaagtttga atgaacgtgc gactgttgat
    17161 tatattattt ctgaaggtct ttacaatcac cgtttattta aggatgaaga agaacgtaaa
    17221 gagaaagttc aaaatattat ccgtgaagta ggtcttcttg ctgagcactt gactcgttac
    17281 cctcatgaat tctcaggcgg tcaacgtcaa cgtatcggta ttgcccgtgc cttggtcatg
    17341 caaccagact ttgttattgc agatgagcca atttcagcct tggacgtttc tgtacgtgcc
    17401 caagtcttga acttgctcaa aaaattccaa aaagagctcg gcctgaccta tctcttcatc
    17461 gcccatgact tgtcggttgt tcgctttatt tcagatcgta tcgcagttat ttacaagggt
    17521 gttattgtag aggttgcaga aacagaagaa ttgtttaaca atccaattca cccatatact
    17581 caagccttgc tttcagcggt accaatccca gatccaatct tggaacgtaa gaaggtcttg
    17641 aaggtttacg acccaagtca acacgactat gagactgata agccatctat ggtagaaatc
    17701 cgtccaggtc actatgtttg ggcgaaccaa gccgaattgg cacgttatca aaaaggacta
    17761 aactaataat ggttttataa tttccatgtc aatttttatg ggaattataa aacttttttg
    17821 ttggactgat ttgaaaaact ttgaaagctt cctgaaaga
//
LOCUS       DAVBCA010000046        17721 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.046, whole genome shotgun sequence.
ACCESSION   DAVBCA010000046 DAVBCA010000000
VERSION     DAVBCA010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17721)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17721)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17721
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.046"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..224)
                     /locus_tag="VQU19_001507"
     CDS             complement(<1..224)
                     /locus_tag="VQU19_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAM domain-containing protein"
                     /protein_id="HET2480739.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCT"
     gene            262..1038
                     /gene="recX"
                     /locus_tag="VQU19_001508"
     CDS             262..1038
                     /gene="recX"
                     /locus_tag="VQU19_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HET2480740.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKW
                     INDGQYAYAIINANQLSGDKGPYVLTQKLAQKGISKSTIEEILNDFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYFDAKIAFDELDSQVDEETTQELIFKELDK
                     QYTKYARKYEGYKLKQRLTQVLARKGYDFSDIASALREYL"
     gene            1127..1660
                     /locus_tag="VQU19_001509"
     CDS             1127..1660
                     /locus_tag="VQU19_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HET2480741.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(2100..2856)
                     /locus_tag="VQU19_001510"
                     /pseudo
     CDS             complement(2100..2856)
                     /locus_tag="VQU19_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567550.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
     gene            complement(2994..4616)
                     /gene="groL"
                     /locus_tag="VQU19_001511"
     CDS             complement(2994..4616)
                     /gene="groL"
                     /locus_tag="VQU19_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HET2480742.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(4632..4916)
                     /gene="groES"
                     /locus_tag="VQU19_001512"
     CDS             complement(4632..4916)
                     /gene="groES"
                     /locus_tag="VQU19_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HET2480743.1"
                     /translation="MLKPLGDRVVLKIEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(5186..5581)
                     /locus_tag="VQU19_001513"
     CDS             complement(5186..5581)
                     /locus_tag="VQU19_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HET2480744.1"
                     /translation="MYNKVIMIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            complement(5659..6420)
                     /locus_tag="VQU19_001514"
     CDS             complement(5659..6420)
                     /locus_tag="VQU19_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HET2480745.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMIKVNQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMIHKK"
     gene            complement(6453..7079)
                     /locus_tag="VQU19_001515"
     CDS             complement(6453..7079)
                     /locus_tag="VQU19_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HET2480746.1"
                     /translation="MIFTYNKEHVSDVLMVIVKNSGDAKLNVERKGKVARVFLKENGE
                     TVAWNIFEVSSLFEIAERGQVFLSDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKIVQIVAGAPNARVGLKTIVALPGAMMPKGNFIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            complement(7095..7412)
                     /locus_tag="VQU19_001516"
     CDS             complement(7095..7412)
                     /locus_tag="VQU19_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HET2480747.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKEQINDFLA
                     GLK"
     gene            complement(7409..7708)
                     /locus_tag="VQU19_001517"
     CDS             complement(7409..7708)
                     /locus_tag="VQU19_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HET2480748.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDHFSDMGEIATLYVQVYESSLESLVGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            complement(7993..8184)
                     /locus_tag="VQU19_001518"
     CDS             complement(7993..8184)
                     /locus_tag="VQU19_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HET2480749.1"
                     /translation="MYYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGSMIANDWVKDNGK"
     gene            complement(8345..9019)
                     /locus_tag="VQU19_001519"
     CDS             complement(8345..9019)
                     /locus_tag="VQU19_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480750.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLALIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLTIRGDVAFGKL
                     EIVYVK"
     gene            complement(9025..9471)
                     /locus_tag="VQU19_001520"
     CDS             complement(9025..9471)
                     /locus_tag="VQU19_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2480751.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(9573..10088)
                     /locus_tag="VQU19_001521"
     CDS             complement(9573..10088)
                     /locus_tag="VQU19_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HET2480752.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVCVLIPASGFVALSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLFLHVS"
     gene            complement(10085..10447)
                     /locus_tag="VQU19_001522"
     CDS             complement(10085..10447)
                     /locus_tag="VQU19_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 family protein"
                     /protein_id="HET2480753.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICSVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(10513..12372)
                     /locus_tag="VQU19_001523"
                     /pseudo
     CDS             complement(10513..12372)
                     /locus_tag="VQU19_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850459.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
     gene            complement(12389..12859)
                     /locus_tag="VQU19_001524"
     CDS             complement(12389..12859)
                     /locus_tag="VQU19_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HET2480754.1"
                     /translation="MDKPMLVFKRFGHQIHLMVQKEAKRCGIEFMGGPQGQVVHFLDN
                     REKNQDLVLIKDIEQELNITKSVASNLVKRIVQNGLVELEASPVDKRAKFVRLTDKAR
                     SQMQQVKAFFERIDKQLMEDIDEDELLIFEKVLGQLQANIKGIGGENKEISQKN"
     gene            complement(12983..13699)
                     /locus_tag="VQU19_001525"
     CDS             complement(12983..13699)
                     /locus_tag="VQU19_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET2480755.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(14580..15989)
                     /gene="ply"
                     /locus_tag="VQU19_001526"
     CDS             complement(14580..15989)
                     /gene="ply"
                     /locus_tag="VQU19_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HET2480756.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQHEKITAHSMEQ
                     LKVKFGSDFEKIGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLRQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFESLIKGVAPQTEW
                     KQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTSFL
                     RDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWDELSYDHQGKEVLTP
                     KAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRKRT
                     ISIWGTTLYPQVEDKVEND"
     gene            complement(16000..16332)
                     /locus_tag="VQU19_001527"
     CDS             complement(16000..16332)
                     /locus_tag="VQU19_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480757.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPTSYLARRRRNVSEELYEEILDYLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            complement(16403..17011)
                     /locus_tag="VQU19_001528"
     CDS             complement(16403..17011)
                     /locus_tag="VQU19_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480758.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(17024..17482)
                     /locus_tag="VQU19_001529"
     CDS             complement(17024..17482)
                     /locus_tag="VQU19_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HET2480759.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            17607..>17721
                     /locus_tag="VQU19_001530"
     CDS             17607..>17721
                     /locus_tag="VQU19_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HET2480760.1"
                     /translation="MNYEASKQLTDTRFKRLVGVQRTTFEEMLAVLKTAYQK"
BASE COUNT         5233 a         3942 c         3237 g         5309 t
ORIGIN      
        1 atagtacaag atggcacaat tcgaaattta gacttcttgt tgaccttcag taattttgct
       61 tcaacaaagt tgcgtctaat agaagtaatc tgacaataga tatcttcgcc tttgagagct
      121 cctggtacaa agactaatgt tttttggtaa aagccgattc cctcaccgtt aattcccatg
      181 cgcttgattt ttaatggtat tttttgtttc actttcagat tcatacccct atcttatcac
      241 attttgagtt ataatagagc tatgaaaatc acaaaacttg aaaagaaaaa aagactctat
      301 ctgatggagc ttgataatgg cgacaaatgc tatatcaccg aagatacaat tgttcgtttt
      361 atgttatcga gagataaggt gataagcgaa gaggaattga aagagattca agactttgct
      421 caattttctt atggtaagaa tctggccctc taccacttat cctttaaagc acgcactgaa
      481 aaagaagtca gagaatatct gaaaaaatac gatattgata aaaacatcgt ttctcaagtt
      541 attgctaatc ttaaagaaga taagtggatt aatgatggtc agtacgctta tgctatcatc
      601 aatgccaatc aactttcagg agacaaggga ccttatgtac tgactcagaa attagcacaa
      661 aaaggaattt caaaatctac tatagaagaa atcttgaatg attttgattt ttcggaagtt
      721 gctcaacgtg tagccaataa actattgaaa aaatatgagg gaaaacttcc agctcgtgcc
      781 ctgcaagata agattatcca gaacttgact aacaagggct tctcttattt tgatgctaaa
      841 attgcctttg acgaattgga tagtcaagtt gatgaagaaa cgactcagga actcatcttc
      901 aaggaacttg ataagcaata tactaagtat gcccgaaagt atgaaggata caaactgaag
      961 cagcgtttaa ctcaagtttt agcacgaaag ggctacgatt tttcggatat agcaagcgct
     1021 cttagagaat atctttaata tttccaagtg aaattcacag attttaggta attttatggt
     1081 acaatagtaa atgataaact tataaattgt agaaagttgg ttagttatga agcttccaaa
     1141 agaaggcgac tttattacaa ttcaaagtta taagcatgat gggagtctcc accgaacttg
     1201 gcgggacacc atggtactaa aaacaacaga aaacgccatt attggtgtca acgatcatac
     1261 acttgttacc gaaagtgatg gtcgtcgttg ggtcactcga gaaccggcta ttgtttactt
     1321 tcacaagaaa tattggttta atatcattgc catgattcgt gataatggaa cttcttacta
     1381 ttgcaatatg gctagcccct actatctgga tgaagaagca ctgaagtata ttgattacga
     1441 tttggatgtt aaaattttta cagatgggga aaaacgtctc ttggacgttg aagagtacga
     1501 gcgtcacaaa cgcaaaatga attattctga tgacttggac tatattttaa aagaacatgt
     1561 caaaattctt gttgattgga ttaacaatgg acgtggtcct ttctcagaag cctatgtaaa
     1621 catttggtac aagcgctatg tagaactaaa gaatcggtaa agttgtcaaa ggtcaggaac
     1681 aaaatcctga ccttgttttt ttggtagtat aaaataaatt gtgtaaacac aaaaaggaat
     1741 aaatccatta tagcagagtt acaacacatt tctataaaga aatttattcc tacgactcag
     1801 tttggcatgc ttaacttcct aactcaaaaa caaagcatcg attaatttat ccgttcttct
     1861 tttgaaacag atttgaactg ataattgctc gttttaattt aagaagctct tttgagcaaa
     1921 acttcatttt tttaagagtc caacaatttc tgtctatcgc ttttctacta gcaaaaaacc
     1981 tcccttgagg caagttttca tttatatatc taatttcgta acagtatagt aaaatgaaat
     2041 aaggacagtc aaatcgattt ctaacaatgt tttagaagta gaggtgtact attctagttt
     2101 caatctacta taaatttgat atgagaatag tctttctcaa catccttatc caacaagcat
     2161 gctgtggcgt ccttcttaac ttgaaccagg tcaatattct gggcttgggc tgccatagac
     2221 gcagccacaa taacattgac gatagatatc atactcctca cacatctcta ctgaacgttt
     2281 gtagccttga tttttcttga aatcgttggg aagatagtgg gtcgtgtaaa ttttttgcac
     2341 atcgattccg atgctattga tggtttgaga attcttatga ggactgatgg tcaaggctga
     2401 accaaagtag tcaaagccca agtccatagc cacttgcgct gttttatcca gtcggtagtc
     2461 aaaacaaacc ttgcaacggt cgccaccttc gggctcctcc tctagtcccc taactagttt
     2521 tcggtattaa ttgggttcgt agggagcttc taggtactga accgtatttc ctgtccgatc
     2581 attaaaatca ctaacaaatt tcttgatgac atagacccgc ttatggtatt ctactttggg
     2641 atggatatta gaattggcaa aatagatggt cacatctgca tacttggtca aatattctag
     2701 tgtataggta ctacaagggg cacagcaaac atgcacgaga atggttggcc gctgctcatt
     2761 tttctcccat gcttgtacca ttttctgcat gacacggtca taattaatct tctgattggg
     2821 gggcatcttg cacagaattt cttctacatc gatcatgttc ttctcctttt tctagtctta
     2881 ttttatcata taagttagaa gagctcaaat caatttagaa gtgaatatta taaaaagaag
     2941 ggttagtcat tccctccttt tgtgtttttt ataagttgtt ttctatagaa agcttacatc
     3001 atcccgccca tcatacttgg atccattgct ggagctgggg ctactggttc tggtttattg
     3061 gctacgactg cttctgttgt caaaatcaag ctggctacag atgctgcatt ttgtagggct
     3121 gaacgactca ctttaactgg atcaatgata ccttgatcaa tcatgttaac ccactcgcca
     3181 gttgctgcgt tgaatcctat accaagctca gcatttttca aacgatcgat aacgatagat
     3241 ccttcaaatc ctgcattgtg agcaatttga cgaacgggtt cttccaaagc acggagaaca
     3301 atattacgtc ctgttgcttc atctcctgtc aattccaagg tagcaacagc tggaatcaca
     3361 ttggcaagag ctgttccacc acctgcaaca ataccttctt caacagctgc acgagtagcg
     3421 ttgagggcat cttcaatgcg gagtttcatt tctttcaact cagtttcagt tgcggctccg
     3481 accttaataa ccgctacacc acctgacaat ttggccaagc gttcttgcaa tttttcacgg
     3541 tcaaattcag aagttgtagt ttcgatttga gacttgataa ccgcaacacg gtgagaaatc
     3601 gcttcaggat ttcctgcacc ttctacaata accgtgctat ctttgtccac ggtcactctc
     3661 gctgcttgac caagagcttc aattgtcgca tctttcaact caagaccaag gtcttctgtg
     3721 ataactgttc cgcctgttaa gatggcgata tcttcaagca tggctttgcg acggtcacca
     3781 aaaccaggtg ccttgactgc tactacgttg aaggttccac gaatcttgtt caaaacaaga
     3841 gttggaagag cctcgccatc cacatcatcc gcaataatca agagtggacg attgctttgg
     3901 agaatgcttt ccaaaagtgg caagatttct tggatattgg aaattttctt gtctgtaatc
     3961 aaaatgtacg gattttcaag gtcagccacc attttttcgc tatcagtcac catgtactgt
     4021 gaaaggtaac cacggtcaaa ctgcattcct tctacgactt caagctctgt ttccatacca
     4081 cgtgactctt cgatggtgat gacaccgtct ttgccaactt tttccattgc ttcagagatg
     4141 tactcaccaa ctttttcaga acgagaagat acggctgcaa cttgagcgat agcttcttta
     4201 ttggcaacag ggatggcgtt gtttttcaaa gcttcaactg ctgcggcaac tgctgtttca
     4261 atcccacgac gaataccgat tggatttgca cctgctgtga cgtttttgat tccttcacgg
     4321 acgattgctt gggtcaaaac agttgcagtt gtagttccat cacctgcgat atcattggtt
     4381 tttgaagcca cttctgatac caatttggca cccatatttt caaaatggtc ttctaattca
     4441 atttctttgg caatagtcac accgtcattg gtaatcaatg gtgagccaaa tgatttttca
     4501 agaacgacat tgcgaccttt tggtcccaag gttactttaa cagtgtctgc aaggatatcg
     4561 acaccacgga ccatagctga acgggcatct gatgaaaatt taatttcttt tgacatactt
     4621 actttctcct tctattcttc aatgattgcc aagatgttag cttcgcctac gatgatgtac
     4681 ttttcatcgc catctttgac atcaagacct gcgtgggctt caactaagac acggtctcca
     4741 gttttaacac ttggagcaac caagtcaccg ttcaaggtac gaacaccttg tccagtagcc
     4801 acaacttggg ctgttttggt tttttcttgg gctgaacctg cgagaacaaa gcccccaacg
     4861 gtttgttctt tttcttctat ttttaagacc acacggtccc ctaatggttt caacatctga
     4921 tttcctccat aatgagatag atattattag cgctctttat acctgagtgc taattcatag
     4981 ttctattgta tcacttagtc agaaataatc aagaaaaaag tctgactttc tcaagataaa
     5041 aagcctgaga ccaactcaga ctttttaatg tttatactca atgaaaatca aagagcaaac
     5101 taggaagcta gccgcaagct gctcaaagca ttgctttgat gttgtggata aagctaacgt
     5161 ggtttgaaga gattttcgaa gagtattaaa atggcaattc ttcctcttcc aagactaaat
     5221 ctgccaaatc ttggcctgca ttattttcac gcatggcacg ttgagcacga ctttccaaga
     5281 gttggaatcc tgttacaagt acttcggtca cgtagttcat ttggccattt ttctcaaagc
     5341 gacgggtacg caattctcca tcaacggaaa tgagactacc tttggttgcg tagcttgcca
     5401 aagtttctgc tagtctgccc cataggacca tattgacaaa atcagcttca cgttcaccgt
     5461 tttggtcttt gtaacgacgg ttcacagcga tagttgctcg cgctaccgac ttgtcattgt
     5521 tggttttgtg caattctggt gtagacgtta aacgcccaat catgataact ttattataca
     5581 tattttcttc ctcctactta tctattcgta ggaaatcaaa aaaagttaca gaaatttgta
     5641 acttttcgag gaaatttctt attttttatg aatcatgaaa cctgtcgcct gttgattggc
     5701 cataatggtc atatctgtaa tctgaacacg gcgaggctga ctggtcacat agactactgt
     5761 gtctgcaata tcctgagctt gcaaggcttc tattccttgg taaacggacg cagctcgctc
     5821 tttatcacca tgaaaacgaa cagttgagaa atctgtttcg acaatcccag gctgaatggt
     5881 tgtcaccttg atatccgttg cgatggtatc aattcgcagt ccatccgaaa aggtcttaac
     5941 cgcagccttg gtagctgagt aaacagcggc accagcatag gcgtagattc ctgcggttga
     6001 ccccatattg ataatatgac cttgattgac ttttatcatt gctggcaaga aacagcgagt
     6061 aaccgccatc agacctttaa cattggtatc caacatggtc aacatatcca actcctcata
     6121 gtcttgatag ggagccaagt caagagccag tccggcgttg ttgaccaaga tatcaatcct
     6181 ccctatcgtt tctagaatat cagagcaaac agtcttcacc atgaccatat ccgtcacatc
     6241 tagtggaaaa gtccagacgg tttgatttgg aaagcttact gcaaactccg acttgaggat
     6301 ttctaatctg tctatccgtc gtcctgttag aacgacatcc tcaccctgct ccagataagc
     6361 acgcgcaatc gcttcaccga ttcctgaggt tgctcccgta atcactacat tttttgccat
     6421 cttatttcct tctatcagat gctgacaagt tcctaggcag tccagtgttt cgctgggtcg
     6481 aacggtgttc cgacaacttg gtcttctgat aattcaagca ccccacgttt ttgcggagca
     6541 tttggcaaat gcaattcacg aggactacac atcatcccaa aactcttttc accacgaagt
     6601 tcgcctggga aaatgaaatt cccttttggc atcatggcac caggaagagc cacaatggtt
     6661 ttcaacccaa cacgcgcatt aggtgctcct gcaacgattt gcactatctt gtcacttgcg
     6721 actgcaactt ggcagatgtt gaggtggtca ctgtctggat gagctaccat ctcgacaatt
     6781 tcaccaacaa caaacttagg ttccttatca ttaacaattt cttctgtaaa accttccgcc
     6841 tgtaattctt ggttcaaacg agcgacttgc tcatctgata aaaagacttg accgcgctct
     6901 gcaatttcaa acaagctcga aacctcaaaa atgttccaag ccactgtttc cccattttct
     6961 ttgaggaaaa cacgggctac cttgcctttg cgttccacat tcagtttggc atctccgcta
     7021 tttttcacga tgaccataag gacatcactg acatgttctt tgttatacgt aaaaatcatt
     7081 gtttcctttt tctcctattt caatcctgct aaaaaatcgt taatttgctc cttactttta
     7141 cggtcgcgat tgacaaaacg accgatttcc ttgtcctttt ctagaacaac aaggctagga
     7201 attccgtaaa catcccagag tttggccaaa tccatatact gatctcggtc cattcgaata
     7261 aaggtgaact ctggattggt ctcttcaatc tctggtaagg caggataaat ataacgacaa
     7321 tcgccacacc agtctgccac aaaaaggaag accttcttgc ccgctttttc cactaaagat
     7381 gctaattctt ctaaacttgc tggctgtatc ataagacttc ctcctcatag actaggtctt
     7441 cattttcata gacaaaggta taatgacggc catcctcaaa aatgacgcca ccaaccaagc
     7501 tctccagact gctttcgtaa acttgaacat aaagggtcgc aatttccccc atgtcggaaa
     7561 aatggtctcg cacaatctct gtcaactctt cctgagtctt catgagctta cggtcatctg
     7621 caactttttt cgtagcaaga gcaaggcttc cgatacctag cagagccaag cctgccatcc
     7681 acattttttt agctttcata ccattcattt taacacaaaa aaggcttcag gacaaatgag
     7741 gaagcagcag aaaagcaagt aaaaagcctc ttcctttaag gaaaaagact tcttatacta
     7801 agagcaaact aggaagctag ccgcaggctg ctcaaaacac ggttttgagg ttgtagataa
     7861 ggcgacgttg acgtggtttg aagagatttt caaagagtat tattcttatt gccaggcacc
     7921 taagttgcca acgtagtaac tatcaggtgt gtaggtattg cgaagcatct tacctgatga
     7981 agccagataa tactacttgc cattgtcttt gacccaatca ttcgcaatca tggaaccaga
     8041 agaacttaca taataccatt ctcccttgtc ataaacccaa gtactgactt tcatggttcc
     8101 tgagcaatta aaggcaaaaa aactgtccaa tatcattcgt tttttaaaag catttgacac
     8161 tacatcatct acgctgtagt acatagatac atcaaacgta aaagccaaaa tatcgaaaaa
     8221 tatacaactt ttaaaggcag catttcattt tttaaagtct aacaaccata gaactgaaat
     8281 cagagcaagg catcaatttc ctactcttag tacgtctatt ttgatggttg aagtgaagat
     8341 ttttttattt aacgtagaca atttccaact tcccaaaagc cacatctcca cggatagtca
     8401 aggttttgct ggttggggct acaggagcgt cagccttagc tgcaccaaag gaggtttcta
     8461 ctttcaaatc tacacgccag tgttgtggaa catagacggt tgcattcccg aaggccactt
     8521 caatatttaa agttgcaaaa tcacctagca tctctgcatt atcatagtag attttagcat
     8581 ccccaaaagc gacttccact tggtcatcta cgagatcttg atcttgctta tagaaggtcc
     8641 cgctaccaaa agcgacttcc ttatccgtga cgactgtttt tttcccattg taccaccatt
     8701 ttttttcatt ccagaactta cttgaatgcg tcagataacc aacaccaagt accaccaaga
     8761 tgctagccca aataagagaa tgattggtaa ctggtaacaa gtcataagcg taatttgcaa
     8821 tgatgagcgc cagtaaacct gtaaaaactg ccgaagtgag atgacgtcta aggatggact
     8881 caatggactt ataagcaaaa aaaacaatac ctagtaaagg ccatatttta ccatccaaag
     8941 aaggaattcc aaaattccct tgcagcaaga tccaagctgc taaaaccaac aaaacaatac
     9001 caaatgcttt ctttttcatg ttttttacct catgtttctt agattttctt ttaggaggga
     9061 ttggtaatgc cgtgagacat gaacctcctt gtgcgtctga taaaaggaaa tggtgcccgt
     9121 tcctgaaaag gacttgtcca ctgagtaaat ctgacggatg tttgcgatcg ttgacttgga
     9181 aactcgatta aaatagcgag gcaagataga ctccaactca tagagcttga ggcgaacctc
     9241 ataagcttcc ttctggttat gagcgtagat cttgctccct tctgtttcaa agaagagaat
     9301 ttctgacagg tctagataat attcacctgt ccccttgtaa aaagtcaacc tcggagcctt
     9361 tgactcttgc aagagccgtt gcaagtctgc aatttcatct gtcaaagtgg gggtcttgat
     9421 gacaatttca gtctcctcta aattgccgtc aatctcaatt cgtaacttca tcacatctcc
     9481 tttctgactc tactatatca aagctaagtt aggaatacaa gggcaaaaaa gcaagtggtc
     9541 aatttgaagc agtaagtggt tgtaggacta gcttaactta catgtaagaa taggaagaaa
     9601 aggaatcccc acaccaaacc acaagcatag ccaaccaaga catccttggg ataatgaaca
     9661 ccccctaaaa ccctcaccaa ccccagcaaa gctgaaaaga tcaagcatac taagccaata
     9721 ggtagactag catgcagaca ggccatggag atgatagttg ccgaaaagac atggcgactg
     9781 ggcatcgacc gtcccgaact atccttatca agaaggggac agatatccca agtttcataa
     9841 ggtctcgggt gattgatttt cttacgaaac agggacaagg ccacaaaacc tgatgcagga
     9901 ataagcacac aaaccccaac ttgctgacca agtcctagtt gcaggtaagt ggtgactagc
     9961 aagatcagat agaccagggg catggcgact gtcatcaaac gattgaaact gcgtaatagg
    10021 aataaaagaa ttggacgact agttagtctg gagctgatat ttcgatacca ttcttgataa
    10081 tttttcattt atgcttctca tacttttcta gaacttgttg agatgttttc cccttggcaa
    10141 gccaatccac tagcttgtcc aagcgacgta tttcctgcat cagaggatca tcaatttcct
    10201 caatacggac actgcaaatc ttccctgtaa ttgcaattcg ttcagggaca taatatggtg
    10261 cttgtctaaa aaaatctccg taagtaacat ccctatccag acaagcaaga acatcactca
    10321 cttcataccc tgtcaaccaa ctggtcactt ggtgaactga ctctgccttt ccaccctttc
    10381 gctcaacttt tgcaatcaag gctaagtaga cagcagcaaa tttcatattg tataatttct
    10441 gactcatact tctctctttc tatgtgtact agtataaata agaaaaagaa ggccgtcaag
    10501 ccttcttttg atttattctt ctgcttcatc ttctgtaaat tgactattgt acaagtcagc
    10561 gtagaagcca ccttgcgcca tcagttcctc atagttgcct tgctcgatga tatttccatc
    10621 tttcatgacc aagatcaagt ctgcatttcg gatggttgac aagcggtggg caatgacaaa
    10681 ggatgtgcgt ccttccatca aacggtccat ggctttttgg atcaattcct ctgtccgtgt
    10741 gtcaacagaa gaagtcgcct catccaaaat caaaagcggt gcatccttaa gaagggcacg
    10801 agcaatagtc aatagttgtt tttgtcctac agacaaggtc acggtgtcat ccaagatggt
    10861 atcatagcca tctggcaagg tcataataaa gtggtgaatt cccacagcct tactagcttc
    10921 catcattcgt tcatcactaa tccctatttg attatagatg agattgtctc gaatagttcc
    10981 ttcaaagagc caggtatcct gcaagaccat tgaaaaggca tcatgcactt ctgaacgcgt
    11041 catagccttg gtatccacac catcaatgtg aatacttccc ttatcaatct catagaattt
    11101 catcaaaaga ttgacaatgg ttgtcttacc agtcccagtc ggcccaacaa tggcaacctt
    11161 ttgaccagca tgaactgtcg cagagaagtc atagtcttga acattgacac cgtccaccag
    11221 aatttctcct gctgacacgt cgtagaaacg tggaatcaga ttgaccagag ttgatttacc
    11281 agaacctgtt gacccaataa aggccactgt ttgaccagtt tctgctttaa agctaacatg
    11341 ttcaataact gcctccgaat ttgccgcata gcggaaggtc acatccttaa actcgacctg
    11401 acctttgaag ttttcatcag tcagctgcac ttgaacaggg ttttggatag aagaatgcaa
    11461 atctaaaact tgattaatcc gcttagcaga gaccatagtt tggggaagaa cgatgaagag
    11521 tgctcccatg agaaggaagt ccatgacaac ctacatggca taagacatga aaacaatcat
    11581 gtcactaaag agaggcagac gcgctatcgg agcagcgtcg ttaatcacat aggccccaat
    11641 ccagtaaatc gccacactca aaccacttga aatccccatc atgataggat tcaaaatagc
    11701 cataagacgg ttgacaaaca aatttaaacg ggtcaattca tcatttactg ctgcaaattt
    11761 ttcattttga taatcctctg cattgtaggc acgaacgaca cgaatacctg ttaaactctc
    11821 acgagtgata ctgttcagtt tatctgtcag cccctgaatc aaggactgtt ttggaaaggc
    11881 tagcgtcatc aaaacggtcg tcatcaggac gttgacaatc actgccacaa gtacggccca
    11941 gagccagtat tctgaatgac ctaaaatctt cccaatagcc cagatagcca taattggacc
    12001 acacgttacc acttgcaagt ccatagtaat caacatttga acttgagtaa tgtcattggt
    12061 agtacgcatc aagaggctag gaattgaaaa tttcttaatc tctgtctgcg agtaatccaa
    12121 aactcggtta aaaatatcac ttctcagcct actagtataa gaagccgcca ctcgggatgc
    12181 aaaaaatcca actgcaacta cggacaagaa ggcaagaaag ggcattccca tcatcatgct
    12241 tgccggctgc cacaactcat ctaaattagt tccttgacta cctagcaaat ccgtaatttt
    12301 cgagatatag gtcggcactt ccaactctag atagaccgaa aagcaagtaa agagaatggc
    12361 tagtaaaatc atcccccatt cttttctact aattcttttg actaatttct ttattctctc
    12421 ctcctattcc cttgatattt gcctgtagtt gaccgagaac tttctcaaaa atcagtaatt
    12481 catcttcatc aatgtcttcc atcaactgct tgtctatgcg ttcaaaaaaa gccttaacct
    12541 gttgcatctg agaacgtgct ttgtccgtca gacgaacaaa cttagcccgc ttatcaacag
    12601 gactcgcctc caattccacc aaaccatttt gcactatacg cttaaccaga ttactagcaa
    12661 cagacttggt aatattgagt tcctgctcga tatctttaat caagaccaag tcttggtttt
    12721 tctcgcgatt atccaaaaaa tgcacaacct gaccttgcgg cccacccata aattcaatgc
    12781 cgcaacgttt ggcttccttt tgcaccatca ggtgaatttg atgaccaaaa cgcttaaaga
    12841 ctaacatcgg tttatccata atctccccct tctaaataaa aatagttctc tggagaataa
    12901 ttaaatttct atgagaacta ttttcttgat taaaaaaatc ccaagtgatt ttctcactta
    12961 ggatcatgtt ctataggtta aattaaaacc catctacgtt cgtataaatc ttttggacgt
    13021 cttcgtcgtc ttcaagaacg ctgtaaagtt tttcaaaggt ttcaaggtct tcgcctgaca
    13081 attccacttc tgactgagga atcatttcca attcagtcac ttggaattct tcaataccag
    13141 actcacggag ggcaacgata gccttgtgaa ggtcagttgg cgctgtgtaa actgtgattg
    13201 taccttcttg tgcttctacg tcatccacat ccacatccgc ttcgagcaat tgctcaaaga
    13261 ctgcgtccgc atcttcacct ccaaatacaa taacaccttt gttgtcaaag aggtaagaaa
    13321 cagaacctga agcgcccatg tttccgccgt ttttaccaaa ggctgcacgg acattggctg
    13381 ctgtacggtt gacgttagaa gtcaaagtat ccacaattag catagagcca tttggcccaa
    13441 aaccttcgta acgtccttct gtaaaggttt cgtctgtgtt tcctttggct ttatcaatcg
    13501 ctttatcgat aatgtgtttt ggcacttggg cttgtttagc acggtcgata acgaatttca
    13561 aagctgagtt tgattctgga tctggatcac cttttttagc tgctacatag atttctacac
    13621 caaattttgc atatacttta gagttggctc catctttagc cgttttcttg gctacgatat
    13681 tggcccattt acgtcccatt aggaatctcc ttttttcaca ttttaatctt tcttattata
    13741 acacaagttt ttttgatttt cactagagga aatggatttt attagcaaat caagctagga
    13801 tagcacttta cctgctaaga tggtcttgcc tttctatctt tatcaacaga cactcatcca
    13861 cattcaaaaa acaaactaga ccattatctg caaatagaaa gtttcagcca agtttgacaa
    13921 agtcagctca aattactgtt tgaagtttgt agatataagc gacaaaaaca atcatactgc
    13981 accttttgtt gacagtctac tccagacata tcatagttca agtaaatact ttgaaatcca
    14041 acagttctta taggcgctat tgtattctaa gaaatcaata gaagagtttc taagcaaacc
    14101 tctaatactc aataaaaatc aaagagcaaa ctagaaagct agccgcaggt tgctcaaaac
    14161 actgttttga ggttgcggat agggctgaca tggtttgaag agattttcga agagtataat
    14221 ttacgtgttc ctaagatgga gaagttagac tagtacactg gcacttctaa accattgcta
    14281 gcaattgatt tgttcatatt taatttcatt ttttccataa atgggtatta gatataaaca
    14341 gcaaaatatt tccgatacgt gtcattcttg aatttccaat catctaaaac aagtaaagga
    14401 taatcaatcc cctgtatatc aaggaattgg ctaccctttt tactttttta cacatcctgt
    14461 ttgatagact cattttaaca tcacgagcat actccaatgg aaatcgctag gcaagagata
    14521 aactttcaga tattcgcaga gagctcatcg cctctttttg tcgcaaacat tcttctctcc
    14581 taatcatttt ctaccttatc ctctacctga ggatagagag ttgttcccca aatagaaatc
    14641 gtccgcttac gcactagtgg caaatcggtt ttttcataaa ccgtacgcca ccattcccag
    14701 gcaagcccgg tacactctct aattttgaca gagagattgc gaacattccc ttttaaagga
    14761 atactagtgg taaagtgagc cgtcaaatcc tgcccatttc tgtcccaagc cttaggagtc
    14821 aagacttcct tgccttgatg atcataggat aattcatccc aagtaatata atattgggca
    14881 acataggcac cactatgatc cagcagtaaa tctccgtttc tgtaagctgt aaccttagtc
    14941 tcaacatagt ctgtactgtt ttgaaaggtc gcaactacat tgtcacgtaa aaaagaagtt
    15001 gtataggaaa tcggcaagcc tggatgatcg gctgtaaagc gactgccttc ttgaatcaag
    15061 tcctctacca tatccacctt gcctgttaca actcgggcac ccgaacttgg gtcgccccct
    15121 aaaataaccg ccttcacttc tgtattgtcc aaaatctgct tccactctgt ctgaggagct
    15181 actcctttta tcaaagattc aaaagcagcc tctacttcat cactcttact cgtggtttcc
    15241 aacttgagat agacttggcg cccataagca acactcgaaa tatagaccaa aggacgctct
    15301 gcagaaattc ctctctgcct taaatcctct accgttacag tatcttgaaa cacatctcct
    15361 ggatttttaa cagcatctac gctgactgta taataaatct gcttaaaatt aacaatctga
    15421 atctgctttt cgcctgaatg gacagagtta aaatcaatat caagagaatt ccctatcttt
    15481 tcaaagtcag aaccaaactt gaccttgagt tgttccatgc tgtgagccgt gattttttca
    15541 tgctgcattc tagctgggac attattgacc tgaccataat cttgatgcca cttagccaac
    15601 aaatcgttta ccgctccgcg aacacttgaa ttgctggggt cttccacttg gagaaagcta
    15661 tcgctacttg ccaaaccagg caaatcaata ctataagtca tcggagcacg atcgaccgca
    15721 agaagagtgg gattattctc taacaaggtc tcatccacta cgagaagtgc tccaggatag
    15781 aggcgactgt cgttggtagc tgttacagaa atatcacttg tatttgtcga caagctccgc
    15841 ttctttcttt cgataacaac aaactcatcg ggtagctgat taccctcttt gatgaaacga
    15901 ttttcaatac tttctccctg atgggtcaag agtttctttt tatcgtaatt catagctagt
    15961 ataaagtcat ttactgcttt atttgccatc ttctacctcc taataagttc ctggattgag
    16021 ttgcataaac tcagacttgt tcagcgaaat cagccgtggt tggactaagt aatccaaaat
    16081 ttcctcgtac aattcttctg agacattgcg tcgccgtctg gctaaataag aagtcggaat
    16141 gaccgtatta tccaacataa ataccttatc taagtcaatc aaggttggtc ttgtaaaagg
    16201 attacgagct agatccggct cttctatcat aaagttcttg accaaacgtc tggtcaagag
    16261 agctggtttg aaggtctgat ttttaaccaa ctctttgttt ttagtcatgc tgttgtcaat
    16321 acagatatac atatgattct tcacagccaa atcgctacta atagtcggaa aaggcaaata
    16381 aagagctaca acatctcctc tcttaatcaa gcaagagcac ccccttttct cctaatgtaa
    16441 catagacagg attgaccaag tcttctgatt gactcagaat ttccaaagtt tgagtttggc
    16501 gcgctgtcaa tttagtagca tcttgtctct tcaatacaaa atgcttgtcg ccaataacct
    16561 tgacaatata atccttctcc aaagctgact ggtaaatcca catcagatgt tgtctgtcct
    16621 gagaactcaa gagagaagga ttttcaagcc tcccgatagt ctgataaaaa tcaaaaacag
    16681 gagctaactc ctgccaatct gattggctag ttgtcaaggc tagaaaaagg gctttgcgag
    16741 ctgatacttc ttggttagcc ttgagagtta ctttcccctc caagtttttt agaaatcggg
    16801 aaactccaga aagcaaattt ttctctaact gcgagaaata aaaacctttc gttcccagac
    16861 ataagtcttt catgtcgctt tctctagcaa ataagagctc aaacatttga tagtaaaaga
    16921 aaaatatctg gcactgggtc gcgctcatct tttccttatc ggcttctttt tttaaccaga
    16981 gcaagggcga caggtagctg gattgagaca tttcctctac ctcctactct tttttaactg
    17041 gagcatctgc actagctgcc acttcttttg actggatact ttcccactgg ttaatctcct
    17101 ctgagataag accttcgcat gtcttgacaa atagggcaaa agccttggtc tttcctgcat
    17161 atttctccgt ttggcattga tagaggaatt tttctttctc caggagttgc gcagtttttt
    17221 ggtaagaaat ccaattttcc tttgcattat acaaattgat aatcccctca cacagcaagc
    17281 cgagactgga taaggcaacc gaaatcaaac ggtagcgatc acctggcata ggaatagcac
    17341 aaaagacagc tatgaggaaa cctgccacga tttctgttat ttttaatacc ttatagcgcc
    17401 tacgatgttg aacgcttttc tttaaaaaat gagctatctg tacgtctaat cgctctgtca
    17461 ggtacatttc ttctggcgtc atattcgtaa ctcctttcat ttactttgat aaccatagta
    17521 taacatattt gaatatcaaa gtatagtaaa aactggacta taacttatta gactccctgc
    17581 gaaacaaaat atggtatagt agttctatga attatgaagc aagtaaacaa ttaactgata
    17641 cacgatttaa gcgtcttgtt ggtgttcagc gtaccacttt tgaagagatg ttagctgtat
    17701 taaaaacagc ttatcaaaaa a
//
LOCUS       DAVBCA010000047        17282 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.047, whole genome shotgun sequence.
ACCESSION   DAVBCA010000047 DAVBCA010000000
VERSION     DAVBCA010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17282)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17282)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17282
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.047"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..692)
                     /locus_tag="VQU19_001531"
     CDS             complement(<1..692)
                     /locus_tag="VQU19_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HET2480761.1"
                     /translation="MNIILIAKPLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSYRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDG"
     gene            complement(803..1057)
                     /locus_tag="VQU19_001532"
     CDS             complement(803..1057)
                     /locus_tag="VQU19_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480762.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRITNRLANDLNNVLKQV
                     DKDTPNTPTWLNSAASKAKDDDRVYKLLKTLIPGENYLSC"
     gene            complement(1415..1948)
                     /locus_tag="VQU19_001533"
     CDS             complement(1415..1948)
                     /locus_tag="VQU19_001533"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2480763.1"
                     /translation="MTIFKEQESEKVAEFLDILDNLKDLPIVYIDETGINRYLYRPYA
                     GAPRGEKVYEKISGRRFERTSIVAGQVDGEFIAPMIYKKSMTSDFFVEWFKTQLLPAL
                     KTPHVIVMGNASFHPKNILDELCIQDKHFFLPLPPYSPDLNPIEQAWAILKKKVTDLL
                     REVPTIFECLECFFKTR"
     gene            complement(1935..2261)
                     /locus_tag="VQU19_001534"
     CDS             complement(1935..2261)
                     /locus_tag="VQU19_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2480764.1"
                     /translation="MAYNTDFKQGALDSIKGGHRHVEAAKVFWCWRQNSLHVGKERRE
                     QRNLERKKRVVKKRKIPLEELKAFVEAHPDAFLREIAAHFDCAVPSVWAALKQIKVTL
                     KKDDDL"
     gene            2495..4213
                     /locus_tag="VQU19_001535"
     CDS             2495..4213
                     /locus_tag="VQU19_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HET2480765.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDVEYLKEVKDVNI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPKEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
     gene            4324..4671
                     /locus_tag="VQU19_001536"
     CDS             4324..4671
                     /locus_tag="VQU19_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HET2480766.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(4949..5785)
                     /locus_tag="VQU19_001537"
     CDS             complement(4949..5785)
                     /locus_tag="VQU19_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2480767.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPEILKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTTLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(5798..6427)
                     /locus_tag="VQU19_001538"
     CDS             complement(5798..6427)
                     /locus_tag="VQU19_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET2480768.1"
                     /translation="MLELRNINKVFGDKQILSNFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLDNLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(6437..7078)
                     /locus_tag="VQU19_001539"
     CDS             complement(6437..7078)
                     /locus_tag="VQU19_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2480769.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(7224..8453)
                     /locus_tag="VQU19_001540"
     CDS             complement(7224..8453)
                     /locus_tag="VQU19_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HET2480770.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLAL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEESENLLT
                     KWMIARSYQEMDDLDTAYEHYQELIGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(8443..9609)
                     /locus_tag="VQU19_001541"
     CDS             complement(8443..9609)
                     /locus_tag="VQU19_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HET2480771.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            9753..10766
                     /locus_tag="VQU19_001542"
     CDS             9753..10766
                     /locus_tag="VQU19_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HET2480772.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FERMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(10811..11230)
                     /locus_tag="VQU19_001543"
     CDS             complement(10811..11230)
                     /locus_tag="VQU19_001543"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HET2480773.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDQVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(11241..12647)
                     /gene="atpD"
                     /locus_tag="VQU19_001544"
     CDS             complement(11241..12647)
                     /gene="atpD"
                     /locus_tag="VQU19_001544"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HET2480774.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFAGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(12733..13611)
                     /locus_tag="VQU19_001545"
     CDS             complement(12733..13611)
                     /locus_tag="VQU19_001545"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HET2480775.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(13627..15132)
                     /locus_tag="VQU19_001546"
     CDS             complement(13627..15132)
                     /locus_tag="VQU19_001546"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HET2480776.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALIHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(15147..15683)
                     /locus_tag="VQU19_001547"
     CDS             complement(15147..15683)
                     /locus_tag="VQU19_001547"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HET2480777.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(15683..16177)
                     /gene="atpF"
                     /locus_tag="VQU19_001548"
     CDS             complement(15683..16177)
                     /gene="atpF"
                     /locus_tag="VQU19_001548"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HET2480778.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(16191..16907)
                     /gene="atpB"
                     /locus_tag="VQU19_001549"
     CDS             complement(16191..16907)
                     /gene="atpB"
                     /locus_tag="VQU19_001549"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HET2480779.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(16942..17142)
                     /locus_tag="VQU19_001550"
     CDS             complement(16942..17142)
                     /locus_tag="VQU19_001550"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HET2480780.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
BASE COUNT         5222 a         3785 c         3096 g         5179 t
ORIGIN      
        1 ccgtcagtag tagtcatgct actgagtttt ttatctgtga cattgtagct ggtaccaatc
       61 agttgttttt tattggtaat gtaggttccg tcactttctt tttctccaat tccagtatca
      121 tttttcaatg atagcaaacg cccttgttca tcaacatagc gaactttcac attttctgag
      181 attagttctg ccaattctga ggtttttttc tttttcttga tttcttcggt tattttccct
      241 ttctcttctt cgggaatatt tagttttgga atgatttttt caacaacggt tcgtgatggt
      301 tccacagtat cttggatgac tgaaaagtca gctagaattg ggagattata ctgaacacgg
      361 taactttgag tgtttactcc tactctttca ttattctctg aaaatacttg tacggtataa
      421 gaaacaacat cttttcctaa tagaacatcc ccagtagaga aatagccgcc ttttcctagt
      481 ttgctatctc cagagcccac ttctttccta attttatcag atagtttttt accagtcagt
      541 acattcgttc gcacaatccc tttgtctacc cctacaaagt gggagaactt tttgaactct
      601 tcagaaccag atctagccca accattatta agggcatttg cttttgtatt tgtattctct
      661 ctcaaaggtt tggcgattag aattatattc atcggcactt agagttgctg ctatatctga
      721 ctcttgaata ccaacttcct tactaccatt tctagcggca gtatatgtgt atttatctgt
      781 ttctacttct agctgattat ccttaacatg ataggtaatt ttctcctggt ataagagtct
      841 tcagtagttt atatactctg tcatcatctt tagctttaga agcagctgag tttagccaag
      901 ttggggtatt aggagtatct ttatcaacct gtttcaagac attattcaag tcatttgcta
      961 gcctattggt tatcctcact gtgaaagttt tcttccagtc tgaaccactt ttattagact
     1021 tagatatgct catgaaatcc tggtcaacat tcaacacaat atcgccttgt tttttagcat
     1081 cttccgttgc ttctgcttca aattgatcat ggagtttttg ttgctctggt gtatagtttt
     1141 tttatttaca cgatttaatg tactattttt tattttagta ttaagaactc cattaatacg
     1201 atttttaaac tctgcttcaa aaaatccctt aatttgttgg tgcgcaagtt caacattcaa
     1261 acctttctta tacaagtctt cattctgata caagtcttca ttctgaacga tttcggctac
     1321 acggtgaatg gtttgatcgt ataccgtctt ctcttaacca gcagtatcct tagttttaat
     1381 gactactcga taggttcctt tagaaccgtt atagtcatct agttttaaaa aagcattcca
     1441 aacattcaaa aatagttgga acttccctta ataaatccgt cactttcttt ttcaagatag
     1501 cccaagcttg ctcaatagga ttcaaatccg gtgaataagg tggtagaggt aagaaaaagt
     1561 gtttatcttg gatgcagagt tcatccaaaa tgttcttggg atgaaaacta gcattgccca
     1621 tgacaataac atgaggtgtc ttcaaagcag gtaggagttg cgttttgaac cactccacaa
     1681 agaaatcgct tgtcatgctt ttcttgtaaa tcatgggagc tataaactct ccgtctactt
     1741 gtcctgcaac aattgaagtt cgctcaaaac gacgtccgct aatcttttca tagactttct
     1801 cccctctagg agcccctgca taaggacgat agaggtagcg gttgattcct gtttcatcaa
     1861 tatatacgat tggtaaatct tttaggttat ccaaaatatc aagaaactca gcgactttct
     1921 ctgactcttg ttccttaaag atcgtcatct ttttttaaag tgaccttaat ctgctttaaa
     1981 gctgcccata ctgaaggaac agcacaatca aaatgtgccg caatttcccg taaaaaagca
     2041 tctggatgag cctctacaaa ggctttcaat tcttctaaag ggatcttacg ctttttgacg
     2101 actcgctttt tccgctctaa gttcctttgt tcacgtcttt cttttcccac gtgaagagag
     2161 ttctgacgcc aacaccaaaa aactttggcc gcctcgacat gtctgtgccc tcctttgatg
     2221 gaatctaatg ctccttgttt aaaatcagta ttatatgcca tagctttatt agaccatgct
     2281 tattttaaac taagcaacta tatcaatgtt ttgttatgag aagacttact ttttttactg
     2341 aaattgaatt tttcctagcc tcaacatcat ataaccccaa aattcaatct gacctggttt
     2401 gaagagatgt tcgaagcaga taaggtttta ctaaaactaa aaaaaatgat ataatcaaac
     2461 tgattaaatg ttttaaaaat aaaggagaat ttgaatgtct taccaagaaa attaccagaa
     2521 atgggttgat tttgtggagc ttcctgacta ccttcgtcaa gatttggaaa atatggacga
     2581 aaaaactaag gaagatgcct tctatacaaa tcttgaattt ggtactgcag gtatgcgtgg
     2641 cttggttggt gctggtacaa accgtatcaa catctacgtt gttcgccaag ctactgaagg
     2701 attggctcgt ttgattgagt caaaaggtgg aaacgagaaa gaacgcggtg tagcaattgc
     2761 ctacgatagc cgtcacttct cacctgagtt tgcctttgaa tctgcggcag ttcttgctaa
     2821 acacggcatc aaatcttacg tatttgaaag ccttcgtccg actccagaac tatcatttgc
     2881 agttcgtcat ctcaactgtt tcgcaggtat catggtcaca gccagccaca accctgctcc
     2941 atttaacggt tacaaggttt acggtgaaga cggtggacaa atgcctccac acgatgcgga
     3001 cgctttgact acttatatcc gtgcaatcga aaacccattt gcagttgaag ttgctgatgt
     3061 ggaaactgaa aaagcttctg gcttgattga agttatcggc gaagctgttg acgtagaata
     3121 ccttaaagag gttaaggacg taaacatcaa cccagccttg attgaagaat ttggtaaaga
     3181 catgaagatt gtctacacac cacttcatgg tactggtgaa atgttggctc gtcgtgctct
     3241 tgcccaagca ggatttgact ctgttcaagt tgttgaagcg caagcaactg ctgacccaga
     3301 cttctcaact gtaacatctc caaacccaga aagccaagca gcctttgccc ttgctgaaga
     3361 acttggtcgt caagttggtg cagatgttct tgtcgcaact gacccagacg ctgaccgtgt
     3421 tggtgttgaa gttcttcaaa aagatggtag ctacctcaac ctttcaggta accaaatcgg
     3481 tgctatcatg gctaaataca tcttggaagc tcacaaaaac gctggaactc ttcctgaaaa
     3541 tgccgctctc tgcaaatcta tcgtttcaac tgacttggta acgaagattg ctgaaagcta
     3601 cggcgcaact atgttcaacg tcttgacagg tttcaaattt atcgctgaaa aaatccaaga
     3661 attcgaagaa aaacacaacc acacttacat gatgggattt gaagaaagct tcggttactt
     3721 gattaaacca tttgtacgtg ataaagatgc catccaagcc gttcttgtcg ttgctgaact
     3781 tgctgcctac taccgttctc gtggtttgac acttgctgac ggtatcgaag aaatctataa
     3841 agaatatggc tactacgcag aaaaaacaat ctctgttact ctttcaggtg tcgatggtgc
     3901 tgaacaaatc aaagcgatta tggctaaatt ccgcaacaat gctccaaaag aatggaacgc
     3961 aacagctatc actgtcgtag aagacttcaa ggcacaaact gctactgttg ctgacggtac
     4021 tgttacaaac ttgacaactc ctccaagtga tgtgttgaaa tacacacttg ctgacggttc
     4081 atggattgcc gttcgccctt caggtacaga accaaaaatc aagttctaca ttgcagttgt
     4141 aggagaaacc aacgaagaat cacaagctaa gattgctaac atcgaagcag aaatcaatgc
     4201 atttgtaaaa taaagaccta taaaagatga gaccaaccaa cctcatcttt tttcgtatca
     4261 aatctaagca attttagaaa ctttatggca tactagactt atcaatgaaa gcgaggtaat
     4321 ctcatggaac aatttttaga taacatcaaa gaccttgaag tcactacagt tgtgcgtgcg
     4381 caagaagctc ttgataaaaa agaaactgca accttcttta tcggtcgcaa aacttgccct
     4441 tactgccgta aatttgcagg tacattgtca ggtgtcgtag ctgaaaccaa agctcacatt
     4501 tacttcatca atagtgaaga accaagccaa ctcaatgatt tgcaagcatt ccgctcacgc
     4561 tatggaatcc caactgtacc aggttttgtt catattacag atggacaaat caacgtccgt
     4621 tgcgactctt caatgtcagc acaagaaatc aaagatttcg caggattgta aaaaatcagc
     4681 taacaagtct taaaatcaca aaaacgcata atgtaaggtg caaaaacctt gatattatgc
     4741 gttttattgt tcctaaaaca gttacatcag catttcatta cagaacattt taattttgga
     4801 agtcaaatca atttttaaca atgttttaga aatcacagtg ggctattcca tattaaatta
     4861 tccagattca atcgctatta tcgttttcct agattacaaa aaaactgcgt tttgctaatc
     4921 aaaacgtagt ctcagccact attttatctt actgtccttc ttttacttct ttggttgcta
     4981 catcttctcc aaaccatttt tggctgattt cttggaactt gccgtccttg taaagactag
     5041 aaaaagcttc atttatcttc ttaaccaagg ttgtatcttc cttacgggct ccaaccgcaa
     5101 aagcttctgt ttctagtcca actgtaaaga cattataatc gtttaaaaca ccttctgctt
     5161 ctaaataata gtttgcatag acacggtcaa tcaatagacc atcaattcga tcgtttttca
     5221 aatcaatcaa ggcttcatta aaggtttggt attgattcgc ttccttatta gcgacaatat
     5281 tcttcaaaat ttctggattt gcttcaaagt ccgcataacc agatgaacca gcttgagctc
     5341 ctaatgtctt tccagtcata tcctttgcag tcgtgatacc agatgatttc ttcgtaacca
     5401 atacctgctc attcttcata tatgagttac tgaaagccac cttttcacgg cgttcgtctg
     5461 tagcggaata gccattccaa atcagatcaa tcgttccttt tgtcaattca gcttctttca
     5521 aatcccaatc aatcggttgc caatttaccg tgattccgta tttttcaaaa acagctgtag
     5581 ctaaatcaat atcaaatcct gcataagaac catctttctg agcaaatccc attggaacaa
     5641 aagtactatc aaatccaata gtaatagact tgttagactg gtactttgac caattatctc
     5701 cactagtttc gctagaattt ttcccacaag ctactaagaa caaagcagtc atcagactga
     5761 ctaatacaag catccatttt ttcatccatt tttcctccta tttaggttct actttcaata
     5821 atacatctgc gatattttca gcaaactgca aatcatgggt aaccacaatc tgggtcatcc
     5881 caagttccct attttgcaag attagcttct ccacttccaa acgtaattct ggatccaggg
     5941 cagaagttgg ttcatcgtag ccaatgattt ctgggtcaat catcatagca cgcgccaaag
     6001 ccacccgctg cttttgccca ccagatagtg agaaaggata ggcctctgcg tgtcctccta
     6061 gtcctaactg ttccaagagt ccactcgcct tcttctcagc ctcttcctgc ttcattccca
     6121 tggtcttcac aggcgataag gtcaaattgt ccagaactga taaatgaggg aacagttgaa
     6181 aatcttggaa tacaaatccc agtagattgc gcttctgcaa ttcatccagc tctaaaggtt
     6241 gtccattata aaagatttgc cctgaatcaa tggtttcaag acctgcaagc atacgtaaaa
     6301 gagttgtctt acctccacca gaaggtccaa cgatagccag gatttgcttt tcaggaatac
     6361 ttagactgaa attagacagg atttgtttgt ctccaaagac tttattgata tttcgtaatt
     6421 ctaacatggc agcctcctat ctataataac tatacttctt ctcaactttt ttggaaataa
     6481 ttgtcacaat cccaatcaaa atcaaataaa tggctcctgc caagaacata ggaactagac
     6541 tagcatcgcg gttagcagct gttcgactag ccaagataag gtctgaaatt ccgagagcat
     6601 agaccaaaga agtatccttg accaaactca taacttcatt aaagacacta ggaagaacga
     6661 tcttggtcac ttggggcaag ataatatagc gcactctgtc aaaagggcta aacttcaaga
     6721 ccttggcggc ctcatactgt cctcttggaa tagtgtcaat tcccccacgg aaaatttctg
     6781 caaagtaagc tgcatagttg agaacaaagg caataatagc tgcaggaagg cggtctaaac
     6841 gaatcccaat acttgggagc acataataga taaaaatcag ttgcaagagt aagggggttc
     6901 ctcgcataac ccagatgtaa atgttaatca gataatggag gggcttccaa tggacttgca
     6961 aggcaaaggc aatcaaaacg cccaagggaa tcgaaaatag caagaccagt gcaaagacct
     7021 gtacagtcgt gctcgcacca ttcagtaaac tcggtaatat ctcaaataaa taagacatac
     7081 tgcacctcct aaaagtaatt gttcctatta tagcatgaat aaacaagatt accaagtatt
     7141 tttgtaaaaa gattctacca tatacaaata aaaaccgtag ctatcaaaag agataaacta
     7201 cagttctata tgtttaaaca ttcttacaat ctctcaaaca gttcttgcat ttgcacatca
     7261 tctggaacca gttttaagta agtgtgagca tggacttttg cttcttcaaa atgtcccaat
     7321 tcacgcaaga gatagatata gtgttccaga aattctggat tgtccttcaa atctcctatc
     7381 aactcttgat aatgctcata agcagtatcc aaatcgtcca tttcttgata agaacgagca
     7441 atcatccact tggtcaaaag attttctgac tcctcactct gcaagtctag aatatcctca
     7501 taacgctcct gctccagata aatagtggct aaacgaagca agatttcttc tgtatcctca
     7561 gcgtcttctt ttgcagtaag gagataattt tctgcaccac tagcatcatg caattcataa
     7621 gaaaattgtg aagcagctag caagaggcga gtttcaaagg gatttttctc taatccttgc
     7681 ttagcgatac gcagggcttc ttgaacttga tgttccttat gtaaagcctg actgtaccca
     7741 tactcatagc cttcaaagtc aggagaaatg gtatcaagct gcttaaagta gagggtggct
     7801 ttttgatatt cttcttgatc aaaataaaga ctggccaact caaaagctgt taagtcatcg
     7861 tattctaact ccagggcttt ttctaaaaac tcagtagccg tttcaaattt ccctaactga
     7921 gcataggcaa agccaattcg ttgataggtg gaaatgcccg tttgctcata aatcgagcga
     7981 ttatctaact gggcataggc ttgaatagcc gcttggtaat tttccaactc actatccaac
     8041 tctgccaaac ccaatatcaa gagagaatcc tctgagtagg tcaaggcctc caataatttc
     8101 tcacgtgcca catctgtcaa accttccagc tggtaaaggt ctgccttcag agccaaagac
     8161 gagacatacc agtcactgtc agcttggatt tcctcaagat aggtaaaggc ttcttctatt
     8221 tgaccatcct cgctagcaat tgcagctaga ttaagatgaa cctctggaaa atcctctaca
     8281 attttcaggt aaatttcctt ggcctgagga tagaaaccaa tcccttcaag ataagttgcc
     8341 aactcataca gaagatcact tgaatcattt tctaaagctt tggcgaaata atgctcagcc
     8401 ttagttaaat cttgctcctc caaagcctgt aacatctgtt gactattgtt cactcttgac
     8461 ttcctcaccc tctaattcat atagaccact gactacctta taccattcga aaatggctga
     8521 aatgacaacc ttagcagagg cataaaccgg aataccaagt aaaactcccc agataccaaa
     8581 catagatcct gaagttaaca aaacaaagag aacattaata gggtggatgt ttaattgact
     8641 tcccaaaatc aatggagaga caaaacggcc ttcaatagtt tgttctacga taaagacaat
     8701 cactactttc aaaagcatga ctggaccagc aatcaaaccc aatactagag caggaagcat
     8761 ggctagaaag ctaccaagat aagggaccag atttaaaata ccagcagtaa cccccagcgt
     8821 aaccgcatag cgtagaccaa taatcttgaa gaagatgata aacattactg ctacaataat
     8881 agccactgtc acttgccctc gaacatagtt ggacaactgt tgattcacat ctgataaaac
     8941 ttgtccaaca ggttccttca attttcttgg aatgaattgg gtcaaatagt tacgcaagcc
     9001 tttcccatca cgcaagagat aaaagagcat gaaaggaacg ataatcaagg caacaatcac
     9061 ttgagaagct ccgctaataa aggcactcac ccagttgact gcctgagatg aaaccttact
     9121 tgccaaaact gtagcctggc tagaaaaatt ggtcaaaact tgctctaatt gaggtctgaa
     9181 atcatctggc aggtgctggg ctaccaatcc attaacaatc ctatctatat cttctaagta
     9241 aacaggaacg tttcttgcaa aggtcaaaac ctgacgttgc agatttggaa tggcgactgc
     9301 caagccccaa atgataaaga gagcgatgat aacaaagaca atagtgatag ctataacacg
     9361 attaacctta tgcttctcca tccaatcaac aataggattc aacaaataat ataacaaacc
     9421 agacaaaatg actggcaaca tcacaactgc taaaaagtct aaaacaggtg aaaatagaaa
     9481 actaatctta cttaaaataa aaagattcag tcccaataat aaggttacta aaaataccgt
     9541 aattgccttg ttatctaaaa accacttgaa aaaccaagat aggctaaaat gtttctcttt
     9601 ttgctccata aatacttcct ttctattgtt ctctcattat accatttttg aaacaaaata
     9661 actctttttt aaagtgctta catctaattg gatatcttta atttacttgt ttttgtgata
     9721 taatagtctt atctttacac agaggtatag taatgaaaga aactgtttat tttggaactt
     9781 atacacgtcg tacttctcaa gggatttaca aggcagactt tgatacagaa actggtcagc
     9841 tttcaaatct agaacttttt gcagctgagc caagtccaac ctaccttgcc tttgaccagc
     9901 accaacattt atacactgtt ggtagccaag acgataaggg gggaattgca gcctatcaaa
     9961 ctgacgggac tgtgttaaat catgttgttg aagaaggagc tccccactgt tatgttgctg
    10021 tcgatgaaaa gcgtgatttg gtttacgcag ccaactatca caagggacaa gtccttgttt
    10081 ataaacgcca ggaagatggt agtcttctac ttagtgatat ggatcaacac agtggccaag
    10141 gtccacatga aaatcaagct tccccccatg ttcactatac agatttaaca cctgaccact
    10201 atctagtgac ctgcgacttg ggaactgacc aagtcatcac ctatgacctc gatcaagaag
    10261 gaaaattatc taagctctat acctatcaca gcaagccagg agcaggctca cgccatatca
    10321 ttttccataa ccactataaa atcgcttatc tcatttgtga actcaatagt actatcgaag
    10381 ttttaatcta cgatggcgtt ggcgaatttg aacgtatgca ggtcatttca actttaccgg
    10441 aagcttacga aggctttaat ggaaccgctg ctattcatct ctctaaagac ggtaaatacc
    10501 tctacgcttc taaccgtggc catgattcta tcgcagtata taccatcctt gcggacggta
    10561 gcttagagtt attagaaatc gttccaacgc atggtcagac tccacgtgat tttgatttga
    10621 cacccgacca aaaatttctc attgttgtcc atcaagactc tgacaatgca actgtcttta
    10681 aacgtaattg tgacaatggt cgtctagcag aactctccaa cgacttccat gttcccgaag
    10741 cagtctgcat ccgttttgct ccttaaaaca ccataaaaaa tgaacttggt attttcaagt
    10801 tcattttttc ttatagtcta tttccgacat taatacggtt aatagcacgt tgcaaagcaa
    10861 tcttagcacg acgttcttgg tcaatcaaat gtttgtcttg tgcttcttca attgcacgtt
    10921 ctgcacgaag tttggcacgt tctgcacgac tgatatcgat atcacgagca cgttctgcag
    10981 agtcagcgac gattgtgatc atatcattgg caatttcaat aacaccaccg tttactgcaa
    11041 tccagttcac ttgatcttta tcatcgatac gttttacctt tacttcatca actgctaaaa
    11101 ccgcaatcat attttcatgt cgtggcaaga tccccatctc accatccaga gttcgaaccg
    11161 atacatagct ggcatggtga tcatagacga gaccatctgg tgtcacgatc tggacagtta
    11221 actgagccat agttcacctc ttaaaatccc attttttcag cttttgcaat cacatcttcg
    11281 atagaaccta caccacggaa ggcatcttct ggcaagtggt cgtatttacc atcaaggatt
    11341 tccttaaagc cacgtacagt ttcagcaact ggaacataag aacctggctg accagtaaat
    11401 tgttccgcaa cattgaagtt ttgtgacaag aagaactgga tacgacgggc gcgagcaacc
    11461 aaggtctttt cttcatcaga aagttcatcc ataccaagga tagcaatgat atcttgcaat
    11521 tcatggtaac gttgaaggac acgttttact tcagcagcaa ctgcatagtg ctcttctcca
    11581 acgatttcag gtgccaaggc acgtgagctt gaagcaagtg ggtcaacggc tgggtagata
    11641 cccaattgta ccaacttacg ttccaagttt gttgttgaat ccaagtgagc gaaggctgtt
    11701 gctggcgctg ggtcagtata gtcatccgct ggcacataga tagcctggat agaggttaca
    11761 gaacccttct tggttgatgt gatacgttct tgcaattgac ccatttccgt agcaagtgtt
    11821 ggttggtaac caacggctga tggcatacga cccaaaaggg cagatacttc tgaaccagcc
    11881 tgagtgaaac ggaagatatt atcgataaag agaagcacgt cttggccttc cacatcacgg
    11941 aagtattcag cgattgtcaa accagtaagg gcaacacgca tacgtgctcc tggtggctca
    12001 ttcatctgac caaagaccat ggctgttttc tcgataacgc ctgattcttt catttcccag
    12061 taaaggtcat tcccctcacg agtacgttcc ccaacaccag caaatactga aataccaccg
    12121 tgctcttggg caatgttgtg aatcaattct tggattaaga cagttttacc aactccggca
    12181 ccaccgaaaa gtccaacttt accaccttta aggtaagggg caagaaggtc aataaccttg
    12241 atccctgttt caaggatttc agaagaggta gacaactcat caaaagttgg agctttttta
    12301 tgaattggct gacgctctgc gtcttctgta aaaggagctt ccaagtcaat ggtatctccc
    12361 aaaacgttga agacacgtcc caaagtttct ttacctactg gtacagagat tggacgacct
    12421 gtgtccaata cttccattcc acgagtcaac ccatctgttg attccatggc gatagtacga
    12481 accataccat ctcctaactc caaggctact tcaaggacga tttttgtttt tctttcgtca
    12541 tttttgtaga cgacaagtgc attgttaatc tcaggaagtt tttcccctgc tgcaaacaaa
    12601 acgtctacaa cgggaccgat aacctgagca attttacctg aactcatctc cttctcctat
    12661 tctatataag atactgtcgg ttcctagctc aactaggtcc taagttcatt ttcatacgag
    12721 ctggactaga gcctattcta aggcactagc acctgctacg atttctgtaa tttcttgtgt
    12781 aatcgccgcc tgtctggcac ggttatactg aattgtcaaa tcattgatga ctttcttagc
    12841 attatctgtc gctgtttgca tggctgtcat acccgcagca ttctcagctg tcttggcatc
    12901 tataatggca ccgtaaatca tactttctgc aaactgaggc aacaactgct ccagaatttc
    12961 ttctcggctg gtttccaatt caaaagtcaa gctgtactct tcatccgctt catttggatc
    13021 caagtcaaca atcggaagca tttgttccac acgcatttga ctggttagcg tattgacatg
    13081 gtggttgtag caaacataaa gctcatcaaa gagttcattt tggtacattt caacagtttt
    13141 tgaaataatc ttacgaactt gatcaaagct aggttggtct gccaagccac gtaattcata
    13201 aagtggttga ataccgcgag ccttaaagaa atcagctccc atcccaccga tacagatcat
    13261 ttcaaaacct ttaccgtctg ggtggtattc ttctttcaac tccataacag ctttcaaaat
    13321 agaggaatta taacctccaa ccaaaccgcg gtctgaagtg ataacgatat agcctgtctt
    13381 cttcacagaa cggctaatca acatcggatt agttgaagca ccagctccat taccatgaag
    13441 gatatctgtc aaaagtttac gcactttctg agcgtaaact tggaagttgc gagcagcttc
    13501 ttcagagcga cctagcttag cagccgatac catttgcatg gcattagtga tttgactcgt
    13561 attttttgtt gaggcgattt ttgttttaat atcatttaga gatactgcca tctgacacct
    13621 ctattcttat tggaagctag attgattgag aaactctgta atcgcagcat ccaagactgc
    13681 ttcttctggc aagtcttttg tatcacgaat ggtttccaaa atctctggat gttgagcatc
    13741 aaagaaggca tggaactctt cctcgaaacg aacaatatca tctactggaa cagtatccaa
    13801 gaaaccatgt atcaaagcat aaagaatggt tacttgtttc tcaacaggta atggtttgtg
    13861 aacaggttgt ttcaagacct caacggtacg acgtccacgg ttcaacttag cctgtgttgc
    13921 tgcgtccaag tcagaaccaa acttagtaaa ggcttccaac tcacggtatg aagcaaggtc
    13981 gatacgaagt gtaccagcaa ccttcttcat ggctttgatt tgtgcagaac cacctacacg
    14041 agatacagat gaacccgcat cgatggctgg acgaatacct gcattgaaga ggccatcgcc
    14101 aaggaagatt tgtccatcag tgatagaaat cacgttggtt gcgatatagg ctgagatatc
    14161 tcctgcttgt gtctcgataa atggtagggc tgtaattgat ccaccaccaa gttcatcaga
    14221 aactttagct gagcgctcaa gcaaacggct gtggagatag aaaacatccc ctgggaaggc
    14281 ttcacgacct ggaggacgac gaagcaagag cgacagttca cgataagcta ccgcttgttt
    14341 tgatagatca tcgtatacaa tcaaaacatg cttaccttga tacataaatt cttccgccat
    14401 agcgacccca gtataaggag ctaggaagag caatggagat ggttgtgaag cagaggctgt
    14461 cacaacgatt gtgtagtcca aggcaccgta ctgacgaagt gtttctactt gcgtacgaac
    14521 tgttgattct ttttgtccaa tcgcgacgta gatacagatc atatcttgat ctttttggtt
    14581 caagattgta tcaatcgcaa tggttgtttt ccctgtctga cggtcaccga taatcaactc
    14641 acgttgacca cgaccaatcg gtacaagggc gtcaatagct ttcaaaccag tttgcaatgg
    14701 ttctgaaaca gacttacgtt gcataacacc aggagctggt gcttctactg gacgagtttt
    14761 atcagtgtgg atttctccaa gaccgtcaac tggacgacca agcggatcca caacacgacc
    14821 aatcagactt tcacctacag ggacttccat gattttccct gtacggcgga ttgtatcgcc
    14881 ttcacggata tctgtaaagt cacctaggat gataatacca acgtctgttg actccaagtt
    14941 ttgagccata ccataagagc cgttttcaaa attcaacaac tctccactca tgacattttc
    15001 aaggccgtga gcacgcgcga taccgtcccc gatataggtt acaacacctg tttcagtcac
    15061 atcaaaattg ggtttgaaat tttcaatttg ttgcttaatt aaagcgctga tttcttgtgc
    15121 gttaattgcc aaaagaacac cactttctat ttcaaatttt ctttaacaac tttaagttgt
    15181 tgtttaatac tcacatcaat tgtcttgtga ttggcaaaaa tgacaaaacc accaatgaga
    15241 ctttcatcga tttgttcttt tacactcctt actttcagag acattttttt ctcaatcaaa
    15301 gggagcaaac gagtcttctg ttcatcagtt agaggatgag cagacgtaat cgtcacttca
    15361 aatcgatttg tttctttttc aagtcggttc aagcaatcta caagcacatc ataaaaaaga
    15421 tttgctctgt gattgtaggc cagaacctgg ataaagtttt gtaataaagg cgacacagaa
    15481 tcttggaaaa aagcaattgt tttttcctta tccgactcgt ctactgccac ttgttttaaa
    15541 aaagaaggca gacctgtttt ttcaacaact tgcttgattt gagtcaagtc tgaaaagata
    15601 cggtcttctt ctcctttttc aagtaccaat tggacaaaag gcatgctgta tttttcaatt
    15661 acctttactg ttttcttgtc cattaagctt ctcctagctg atcgatatac tgatcaatga
    15721 gtgctttatg ggcatgactg tcaaggtttt gtgagatgat tttaccagct aagctgatgg
    15781 tcagatctgc gacctcaccc ttaacactct gtaaagcttc tactttattt tgagcaattt
    15841 cttgattggc tttttctttt aagtgtcctg cttctagttt agcatctgct aagatattag
    15901 ccttactttg ctcagctgtt tcctttgcat tttcaatgat tgtcttagct tctttacggc
    15961 taccagccaa ttcatcttcg cgtttttgag ccaatacttc tgctttttga cgggcttctt
    16021 cagctctgtc aatatctgaa gcaatttttt cagctctttc ttcgaaaatg cctgtaatat
    16081 tagaccatgc aaatttttta atcaagacta gcaaaagaat aaaagagcca gtgattaaaa
    16141 taaaattacc aattaattca cctactgtta cgtgcatcag ttactccttt ctattcctct
    16201 tcaatattaa tcttattccc taaatacaca gatgtcaaaa gagtaaaaac ataagcttgg
    16261 atgcaggaaa taaagacaga aaatgcagtc caagccaaat tagctccaaa ggctactgga
    16321 taccaataaa tagcttggtg ggaaagaaga agtaacaaac tcgtcatgac ctctcctgca
    16381 aagatattcc caaaaatccg caaagccaaa gataagaagt ttgtaaattc ttccaagata
    16441 ttcatcggta tgacaaaaac aggactcata aaagatttta tacttttttt aaatccacga
    16501 cgacgaacgc tttctatatg tgtcaacaaa atgacaagaa aagataaggt taagtcatac
    16561 tgtaaattag cggttggcga actccaccag ttagtcccat cgatcgtttg aagctttgtc
    16621 attaagccaa ggttattggc aatcaccatg aaaaggaata aacaaaggaa aaagagtgaa
    16681 taatctttca tgtagcgcga accaatgtta ggttctgtaa atccaataac aaagtcatag
    16741 acatactcaa gtacattttg ctttcctttg ggtttcaagg tcatattgcg gcttgcccaa
    16801 taaataaaga caaaaataac tcccacaatc aacaaagtca tggctaacat agtcagattg
    16861 aagataacag gaccaataga gatgattgga ttaatacttt cttccatcta aaatcctccc
    16921 ttttcttctc gttccatgta tttatttgat aataaatgag aagacaagag ttacaaagaa
    16981 agttccttca ataaaggcaa cacctaaaaa catcaaacta cgaaactcag aaagcatatc
    17041 tggttggcgt gctactgatt taaacagtcc attcatcaat aaaccttcac cgacagatac
    17101 gcccatacag gcaatacata agcctaaaaa tgttaaattc ataacaaatt ctcctttaaa
    17161 ataaaattta cttacttagt gtagtcctaa aatttaaatt tgtcaacttt taaccgctat
    17221 tggaagcgtt taataaaaat tatttccatt ttgctaaatt tcaagttcaa gttagccatc
    17281 ca
//
LOCUS       DAVBCA010000048        16722 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.048, whole genome shotgun sequence.
ACCESSION   DAVBCA010000048 DAVBCA010000000
VERSION     DAVBCA010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16722)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16722)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16722
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.048"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..89
                     /locus_tag="VQU19_001551"
     CDS             <1..89
                     /locus_tag="VQU19_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HET2480781.1"
                     /translation="STTYRNHRKRFGLRMNLIAGIINHKLEF"
     gene            138..602
                     /locus_tag="VQU19_001552"
     CDS             138..602
                     /locus_tag="VQU19_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
                     /protein_id="HET2480782.1"
                     /translation="MGGHPGFNCLLLDDEVYEDYYLEFEKEEICSVPRPFPETGMLDF
                     QDRSPWLEGQKEIDLSYDLFSTDAVTLDELQSRTIALRSLKHDKGLKVHFAEFPNLII
                     WSTLNKGPFITFEPWSGLSTFLEEGDHLEDKKNVCLLEANQVEELGFEIEVL"
     gene            760..1185
                     /gene="lacA"
                     /locus_tag="VQU19_001553"
     CDS             760..1185
                     /gene="lacA"
                     /locus_tag="VQU19_001553"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HET2480783.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            1216..1731
                     /gene="lacB"
                     /locus_tag="VQU19_001554"
     CDS             1216..1731
                     /gene="lacB"
                     /locus_tag="VQU19_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HET2480784.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPSEENKKLIAKIEHLESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            1742..2671
                     /locus_tag="VQU19_001555"
     CDS             1742..2671
                     /locus_tag="VQU19_001555"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HET2480785.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDDQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKLVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLEELKEVLQESLFTGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAGLLIKA
                     NVLGMLNAQEKMTGHVNMANYQALYDQLIVKEV"
     gene            2673..3653
                     /gene="lacD"
                     /locus_tag="VQU19_001556"
     CDS             2673..3653
                     /gene="lacD"
                     /locus_tag="VQU19_001556"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HET2480786.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKILVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            3887..4723
                     /locus_tag="VQU19_001557"
     CDS             3887..4723
                     /locus_tag="VQU19_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HET2480787.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLIAENH
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALIQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            4759..5076
                     /locus_tag="VQU19_001558"
     CDS             4759..5076
                     /locus_tag="VQU19_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET2480788.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            5078..6772
                     /locus_tag="VQU19_001559"
     CDS             5078..6772
                     /locus_tag="VQU19_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HET2480789.1"
                     /translation="MDKLIIFIEKGKPFFEKLSRNIYLRAIKDGFISSMPAVLFSSIF
                     ILIAAVPNIFGFKWSDEQLAFILKPYNYSMGILALLVAGTTAKSLTDSVNTRSMEKTN
                     QINYMSTFLAAVVGLLILAADPIEGGFANGLLGTRGLLTAFLAAFITVNIYKVCIKNN
                     VTIRLPEEVPPNIAQVFKDVIPFALSVLSIYGLDLIVRNIFGTNVAESVGKILAPLFS
                     ATDGYIGLAIVFGAYAFFWFVGIHGPSVVEPLIVAISYANIEANVQLVQAGMHADKIL
                     NPVTQTFVVTMGGTGATLVVPFMFMWLCKSKRNRIVGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFIPFVTAPIINVWIMKFFVDVLQMNSFSIILPWTTPAPIGIVMGTALAPLSF
                     VLAITLIIIDTLIYYPFVKVYDHQILEEERSGKSNDELKEKVAANFNTAKADAILEKA
                     GVDAAQNTITEETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLP
                     EFDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQAQFD"
     gene            6981..8387
                     /gene="lacG"
                     /locus_tag="VQU19_001560"
     CDS             6981..8387
                     /gene="lacG"
                     /locus_tag="VQU19_001560"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HET2480790.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKDKGYKGEIGVVHAL
                     PTKYPLDPKNPSDVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEVLSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            8430..8612
                     /locus_tag="VQU19_001561"
     CDS             8430..8612
                     /locus_tag="VQU19_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000471575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HET2480791.1"
                     /translation="MFKDFIQSIYEKVYIINFEKCSQIPCLTSEELKSLFLNFINPEE
                     WDTISFDSDFMPFQQS"
     gene            complement(8890..9651)
                     /locus_tag="VQU19_001562"
     CDS             complement(8890..9651)
                     /locus_tag="VQU19_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET2480792.1"
                     /translation="MLKQEKLAKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNVSNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(9833..10795)
                     /gene="nrdF"
                     /locus_tag="VQU19_001563"
     CDS             complement(9833..10795)
                     /gene="nrdF"
                     /locus_tag="VQU19_001563"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HET2480793.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            complement(10983..13142)
                     /gene="nrdE"
                     /locus_tag="VQU19_001564"
     CDS             complement(10983..13142)
                     /gene="nrdE"
                     /locus_tag="VQU19_001564"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HET2480794.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            complement(13223..13441)
                     /gene="nrdH"
                     /locus_tag="VQU19_001565"
     CDS             complement(13223..13441)
                     /gene="nrdH"
                     /locus_tag="VQU19_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HET2480795.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            13792..14055
                     /locus_tag="VQU19_001566"
     CDS             13792..14055
                     /locus_tag="VQU19_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HET2480796.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            14061..15794
                     /gene="ptsP"
                     /locus_tag="VQU19_001567"
     CDS             14061..15794
                     /gene="ptsP"
                     /locus_tag="VQU19_001567"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HET2480797.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            16049..>16722
                     /gene="phtA"
                     /locus_tag="VQU19_001568"
     CDS             16049..>16722
                     /gene="phtA"
                     /locus_tag="VQU19_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HET2480798.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASE"
BASE COUNT         5246 a         2932 c         3471 g         5073 t
ORIGIN      
        1 tttcaacaac ctatcgaaat catcgtaaac gcttcggatt acgaatgaat ttgattgctg
       61 gtattatcaa tcataaacta gaattctagt tttgcaggaa gtctaataaa gaaactagca
      121 aggtcaggcc ttactttatt ggtggacatc caggatttaa ttgtcttcta cttgatgatg
      181 aagtctatga agattattat ctagagtttg agaaagaaga gatttgctct gttccacgtc
      241 ctttcccaga aacaggtatg ttggatttcc aagatagaag tccatggcta gagggacaaa
      301 aagaaataga tcttagttat gatcttttca gcacagatgc agtgactttg gatgaattgc
      361 aatctcgaac aattgccctt cgttctctta aacatgataa gggattgaaa gtgcattttg
      421 cagaatttcc aaacctcatc atctggtcaa ctttgaacaa gggacctttc attacctttg
      481 aaccatggtc tggcttgtca acattccttg aagaaggaga tcatttagaa gataagaaga
      541 atgtttgtct cttagaagcc aatcaggttg aagaattagg gtttgagata gaagttttat
      601 aaaaaaagta aaaaataaat aacaaaaaca aacacaaact gttgacttct tcaaacaata
      661 gtagtatatt atgtttgtga ggactaattg actgtttttt aaagacagcc aatacactgc
      721 tggaatccag catagaaaaa ataaaaagga gtatacaata tgtctattgt tatcggtgca
      781 gatgctgcag gtttgagatt gaaagaagtt gtgaaagact tcttagaaaa agaaaacttc
      841 caccttgtgg atgttacagc tgaaggtcaa gactttgttg atgtgactct cgctgttgct
      901 gcagaagtaa acaaagaaga acaaaacctt ggtatcgtga ttgatgctta tggagctggt
      961 ccatttatgg ttgcaactaa gatcaaagga atggttgctg cagaagtatc tgacgaacgt
     1021 tcagcttata tgactcgtgg ccacaacaac tcacgtatga tcactatggg ggcacaactt
     1081 gttggtgatg aattggctaa aaacatcgct aaaggatttg ttaatggtaa atacgacggt
     1141 ggacgtcatc aaatccgggt tgacatgttg aacaaaatgg gctaattaga ttacagtaag
     1201 aaaggtaagt taaaaatgag aattgcaatt ggatgcgacc acatcgtaac agatgaaaaa
     1261 atggcggttt cagaattttt gaaatcaaaa ggatatgaag tcattgactt tggtacatat
     1321 gaccatacac ggactcacta cccaatcttt ggtaaaaaag taggggaagc tgtaactagc
     1381 ggccaagctg atcttggggt atgtatctgt ggtactggtg ttggtatcaa caacgctgta
     1441 aataaagttc caggtgttcg ttctgccttg gttcgtgata tgacaacagc cctttatgct
     1501 aaagaacaat tgaacgctaa cgttatcggc tttggtggta agattactgg tgaattgctt
     1561 atgtgtgata tcatcgaagc tttcattcat gctgaataca aaccatctga agaaaacaag
     1621 aaattgattg cgaaaattga acaccttgaa agtcacaatg ctcaacaaac agacgcaaac
     1681 ttctttacag aattccttga aaaatgggat cgcggagaat accacgacta agaggtgacc
     1741 tatgatttta acagtcacaa tgaacccatc cattgatatt tcctatccct tggatgagtt
     1801 gaagattgat actgtcaatc gtgtggtgga tgtaaccaaa acggctggtg gtaagggact
     1861 taatgttacc cgagtacttt cagaatttgg tgattctgtt cttgctactg gtttagtggg
     1921 tggcaaactt ggtgagtttt tggttgaaca tatcgatgat caagtaaaga aagatttctt
     1981 ttctattcag ggagaaactc gtaactgtat cgctattctc cacggtgaca accaaacaga
     2041 agttcttgaa aaaggtcctg aagtattgga acaggaaggt caagactttt tggaacattt
     2101 caaaaaactc ttggagtcag ttgaagtagt agccatctca ggtagtctgc cagctggcct
     2161 tccagttgat tactatgcga gcttggtaga gcttgctaat caagctggca agctagtagt
     2221 cttggactgc tctggtgcag cacttcaggc ggttcttgaa tcaccccata aaccgacagt
     2281 aatcaaaccc aataatgagg aattgtctca gcttctagga agagaagttt ctgaggattt
     2341 ggaggaatta aaagaagtcc ttcaagaatc tttgtttaca gggattgaat ggattatcgt
     2401 ttcacttggt gccaacggta cttttgccaa acatggtgac actttctaca aggtagatat
     2461 tcctagaatt caggtggtaa atcctgttgg atctggagac tctactgtgg caggaatttc
     2521 ttcaggactt cttcacaaag aatcggatgc aggattactc atcaaggcaa atgtccttgg
     2581 tatgctcaat gctcaagaaa aaatgactgg tcatgtcaac atggccaact atcaagctct
     2641 atatgatcaa ttaatagtaa aagaggtata aaatggcttt aacagaacaa aaacgtgtac
     2701 gcttagaaaa actttctgat gaaaatggta tcatctcagc tcttgcattt gaccaacgtg
     2761 gtgctttgaa acgcctcatg gctcaacacc aaacagaaga accaactgtg gcccaaatgg
     2821 aagaacttaa aatcttggta gcagatgaat tgactaaata cgcttcatct atgcttcttg
     2881 accctgagta tggacttcca gcaactaagg ctcttgatga aaaagctggt cttctccttg
     2941 cttatgaaaa aacaggttat gacacaacaa gcacaaaacg cttgccagac tgcttggatg
     3001 tttggtctgc aaaacgtatt aaagaagaag gtgcagatgc agttaaattc ttgctttact
     3061 atgatgtaga tagctcagac gaactcaatc aagaaaaaca agcctacatc gaacgcatcg
     3121 gttctgagtg tgtggctgaa gatatcccat tcttccttga aatccttgct tacgatgaaa
     3181 aaattgcgga cgcaggttct gtagaatacg ctaaagtaaa accacacaaa gttatcggtg
     3241 ctatgaaagt cttttcagac ccacgtttta acattgatgt cttgaaagtt gaagttcctg
     3301 ttaacattaa atatgttgaa ggcttcgctg agggtgaagt ggtttacaca cgtgaagaag
     3361 cagcagcctt cttcaaagcg caagatgaag caacgaactt gccatacatc tacttgagtg
     3421 ctggtgtatc agctaaactc ttccaagata ctcttgtatt tgctcatgaa tcaggtgcaa
     3481 actttaacgg agttctttgt ggtcgtgcta catgggcagg gtcagttgaa gcttacatca
     3541 aagatggtga agcagcagct cgcgaatggc ttcgcacaac tggatttgaa aacattgatg
     3601 agctcaataa agttcttcaa acaacagcga cttcatggaa agaacgtgtg taagaaagtc
     3661 ctcctagttt aggaacatga atctaaaaaa atttaaaaaa agttgtatgt aaaggtttac
     3721 aaaataactt acttgtgcta tacttaaatc acaagttaat acaaggtgag tgttactaag
     3781 taatattagg catgatcaca ggtgaattag aaatcagctg attttctagt tcatttgtgg
     3841 tcattttttg tactcatata cctttaagat ataaaaggag gttgacatgt atcgaattct
     3901 aaatccaatg aatcacaatg tctcgcttgt cagaaatgat aagggagaag aggtgattgt
     3961 aattggtaag gggattgcat tcggaaagaa gaagggggat ttgattgctg aaaatcatgt
     4021 tgagaaaatc tttcggatga agaccgaaga gtccagagaa aactttatgg ctcttctcaa
     4081 agatgttccg cttgatttta tcacagtgac ctatgaaatc attgataagc tatcaaagaa
     4141 atatcattat ccgattcaag agtatctcta tgtaaccttg acagatcata tttactgttc
     4201 ttatcaagct ctaattcaag gaaggtacaa ggatagtaat ctgccagata tttctgctaa
     4261 gtatcctgtc gcttttcaaa tcgcaaatga agcttttgaa atttaccgtc agaagctagc
     4321 agatcatttt cctgaggacg aaattattcg gattgcttat catttcatta atgctgaagg
     4381 tgaaaatgaa gtggaacttg tggagtcgat tgataagagg aaagaaattc tcaggaatgt
     4441 tgaagaagtt ttaacggact atgcaattca acgaactaaa aagaataacc atttctatga
     4501 tcgctttatg atccatttga attatttctt ggattattta gacagatcta gagatgataa
     4561 ccaatcactt ctggatatgg aagatcatat taaacaatcc tatccaaaag ccttcgagat
     4621 tggttccaag atctatgatg tgattacgca acatacgggt cttgatttgt ataaaagtga
     4681 acgagtttat ctagttctac atatccaacg tttattgtca taaaaattta tttaaaacta
     4741 tataaggaga attctatcat gaatagagaa gaagtaacat tgttaggttt tgaaatcgta
     4801 gcctatgctg gcgatgctcg ttcaaaacta ttggaagcct tgaaggctgc tgaagctggt
     4861 gattttgaaa aagcggacgc tctggtagag gaagctggta gctgtattgc agaggctcac
     4921 cacgcgcaaa caagtctatt gactaaggaa gcttctggtg aggacttagc gtatagtgtg
     4981 accatgatgc atggtcaaga tcacttgatg acaactatct tgttaaaaga cctaatgcac
     5041 catttaattg aactttacaa gagaggagtt aaataaaatg gataagttaa taatttttat
     5101 tgagaaagga aagcctttct ttgagaaatt atcgagaaat atatacttaa gagcgataaa
     5161 agatggtttt atttccagta tgccagcagt attattctca agtattttta tactaatagc
     5221 tgctgtgccc aatatttttg ggtttaaatg gtctgatgaa cagttagctt ttattttgaa
     5281 accttacaac tactcaatgg ggattttagc tctcttagta gctgggacaa ctgcaaaatc
     5341 gttaacagat tcagttaata cacgtagtat ggagaaaacc aaccaaatca actacatgtc
     5401 aactttttta gcagctgttg ttggattgtt aatactggca gctgatccaa ttgaaggtgg
     5461 atttgctaat ggtcttttag gtactagagg attacttact gcatttttgg cagcttttat
     5521 tacagtaaat atctataaag tatgtattaa aaataatgta accattagac ttcctgaaga
     5581 ggttccacca aatattgcac aagtttttaa agatgttatt ccgtttgcct tatctgttct
     5641 ttcaatatat ggattggatt taattgttag aaatattttt ggtacaaatg tagcagaatc
     5701 tgttggtaaa atattagccc ctctattttc agctactgat ggttatatcg gtttagctat
     5761 tgtatttggt gcttatgctt tcttttggtt tgttggaatt catgggccat ctgttgtaga
     5821 acctttaatt gtagctatca gttatgcaaa tatagaagct aatgttcagc ttgtgcaagc
     5881 tggtatgcac gcagataaaa ttttaaatcc agttactcaa acttttgttg taacaatggg
     5941 tggtactggt gcaacactag tagttccatt tatgtttatg tggttatgta aatcaaaaag
     6001 aaatagaatt gtcggacgtg cgtctgtagt tcctactttc tttggcgtaa atgaaccaat
     6061 cctatttggt gctccaattg ttttaaatcc tatcttcttt attccgtttg ttactgctcc
     6121 tattatcaat gtttggatta tgaaattttt tgtagatgtt ctacaaatga atagtttcag
     6181 tattatttta ccttggacaa cacctgctcc aattggtatt gttatgggaa cggcgctggc
     6241 tccattgtca ttcgtcttgg ctataacttt aatcattatc gacactttaa tctattatcc
     6301 atttgttaaa gtttatgacc atcaaatttt agaagaagaa cgttcaggta agtctaatga
     6361 tgaattgaaa gaaaaagttg ctgcaaactt caacactgca aaagcggatg ctattcttga
     6421 aaaagcgggt gtcgatgcag cacaaaatac catcactgaa gaaacaaatg tcctcgttct
     6481 ctgtgcaggt ggaggaacaa gtggtctcct tgcaaatgct ttgaataagg cagcagcaga
     6541 atacaatgtc cctgtgaaag cagcagcagg cggctatggt gctcaccgtg aaatgttacc
     6601 agagtttgat cttgttatcc ttgcccctca agttgcttca aactttgaag atatgaaagc
     6661 agaaacagat aagctcggta ttaaactagc gaaaacagaa ggcgctcaat acatcaaatt
     6721 aactcgtgat ggaaaaggtg ctcttgcatt cgtacaagcg caattcgatt aaggctagag
     6781 actctgaaat agtctcctat cgttacggaa atcgctatgg cgaatttcct attattaatt
     6841 cgtcggtaaa aagatatcgt ttttacctcc tcatgtcaca attcggtgac ttggtacaag
     6901 aagtgagatg gagaaggatg gctcactgac tcctctcctc tcacttttac tttatttaaa
     6961 tcaagaaata ggtgaaaaaa atgacaaaaa cacttccaaa agactttatt tttggtggcg
     7021 caacagctgc ctatcaagca gaaggtgcta cacatactga tggtaaagga ccagtagcgt
     7081 gggataaata tcttgaagat aactactggt acactgcaga accagccagt gatttttaca
     7141 atcgatatcc agttgacctc aagctagcag aagagtatgg tgtcaatggt attcgaattt
     7201 ctattgcttg gtcacgtatt ttcccgactg gttacggcca agtaaatgct aaaggtgttg
     7261 agttttatca taatttattt gcagagtgtc acaaacgtca tgttgagccc tttgtaactc
     7321 ttcatcactt tgacacgcca gaagctctcc actcaaatgg agacttctta aaccgtgaaa
     7381 atatcgaaca ttttgtagac tacgctgcct tctgttttga agaatttcca gaagtaaact
     7441 attggacaac ctttaatgaa attgggccaa ttggtgatgg tcaatacttg gttgggaaat
     7501 tccctccagg tattcagtac gaccttgcca aagtcttcca atcgcaccac aatatgatgg
     7561 tgtctcatgc gcgtgcagtt aagctatata aagataaagg ctataaaggc gaaattggtg
     7621 ttgttcacgc tctgccaact aagtatcctt tagatcctaa aaatccgtca gatgttcgtg
     7681 cagctgagtt ggaagatatt attcacaata aatttatctt ggatgcaact tatctaggtc
     7741 gctattcagc tgaaacgatg gaaggtgtca accatatctt atcagtcaat ggtggtagct
     7801 tggatcttcg tgaagaagat tttacagcat tagaagcagc aaaagacttg aatgatttcc
     7861 ttggaatcaa ctactatatg agtgactgga tggaagcctt tgatggagaa actgaaatta
     7921 tccataatgg taagggtgag aaaggaagtt ctaaatacca aatcaaaggt gttggtcgtc
     7981 gtgtagctcc tgattatgta ccacgtacgg attgggattg gattatctac cctcaaggtt
     8041 tatatgacca aattatgcgt gtgaagaaag attatcctaa ctacaagaag atttacatca
     8101 ctgaaaatgg tctcggctat aaagatgagt tcgtcgataa cactgtttat gatgatggac
     8161 gtattgatta tgtgaaacaa cacttggagg tcttgtctga tgcgattgca gatggagcga
     8221 atgtaaaagg ttacttcatt tggtcattga tggacgtctt ttcatggtca aatggttatg
     8281 aaaaacgtta cggtctcttc tatgtagact ttgaaactca agaacgttat ccgaagaaat
     8341 cagctcactg gtacaagaaa gtagcggaaa ctcagattat agactagtag aattagtcat
     8401 tagatataga attttagtga gtcaaaaaga tgttcaaaga ttttatccaa tctatttatg
     8461 aaaaagttta tattataaat ttcgaaaaat gctctcaaat accgtgtttg acgagtgaag
     8521 aattgaaaag tctattttta aattttatca atcctgaaga atgggatact atctcctttg
     8581 attcagattt tatgccattt caacaatcgt aaccaatttc tcaaaaaagt taaatcttat
     8641 atttagtact ctgcaaaact cttatctaat cacgttgctt atactcaatg aaaatcaaag
     8701 agcaacttta aactaggaag cgagtcgcag atttctcaat gcatagcttt gaggaattgg
     8761 gcaaaaagtc tttgatatag aaaaagcata gtatcaggtg tttcaacacc tgatactatg
     8821 ctttttattg tgggaagatt tacttttttt cttctgaaat tgagttgtta cccaggctct
     8881 ttcagtttat taaggcttga tgactttaat gtgtttagat agcttaaaaa ggattgaatc
     8941 acttagttta gaatctgaaa caatagtatc aagatttgat acattataaa aagtataaaa
     9001 atcaaactta ttgaacttac tatgatctgc gagtaaatat tttttattag aattatttaa
     9061 agcgatgcgt tgagcctctc cctcttcctc gctaaaagta gctagagctc cgttttgaat
     9121 accattacag ctaacgaaag ctttagaaaa ttggagatta gagagatttt gtagggtcaa
     9181 tgtgccaaca aaagcacctg taatatcgcg ataatttcca cctatcaaaa tcaaatctgt
     9241 taattttcgt tcgcttaaaa tcagaaaaac aggtagactg ttggttacga cgcggatatt
     9301 gtcaataggc aactcacgcg caaaaaactc taatgttgtt cctggtccaa tgaaaatagt
     9361 ttctctttct tctactagac tgcctgcaaa atgggctatt tcttgttttt ctgccgtttg
     9421 gagggcttgt ttttcaatat ttgatcgctc attagtcaaa agggagttgg ttcgaagttt
     9481 ttcagctcca ccatgcacac gaatcagcaa atctttatca gctaattcct gtaaatagcg
     9541 ccttgcagtc atatctgaaa cggctatttc gtccataatc tgtttaactg ttatggttcc
     9601 tttactattt actatctcta aaattttggc taatttttct tgtttgagca tattatcacc
     9661 tcgtttccta ctactatctt accataaaca aactcatcat tcaaatacaa aaacaacaaa
     9721 atgaaacaaa aacaaaaata tcgaagtttg ttttcaaaac tttcgatatt tttgttgggt
     9781 tataactttg atgtttctag tttacttttt gatgattgag agtgatggag aattagtcta
     9841 aaccgtagtt atagtcatcg tcttgcatgg cttcaacttc gccaagaagg taaccatttc
     9901 cgacttgaga gaagaagtca tggttggaag ttcctgttga aataccgttc ataacgattg
     9961 ggttgacatc ttcagctgaa tctgggaaaa gtggatcttg tcccatgttc atgagagctt
    10021 tattggcatt gtagcgaagg aaggttttaa cctcttcagt ccaaccaaca ccgtcataaa
    10081 gactctctgt gtagccttct tcattttcat aaagagtata gagtaggtcg tacatccatt
    10141 ctttgagttt ttcttgctct tcttcaggca attcattgaa accaagttgg aatttgtaac
    10201 caatgtaggt tccgtgaaca gactcgtcac gaataatcaa tttaatgatt tctgcaacgt
    10261 tggctagttt gttgttaccg agatagtaga ggggagtgaa gaaaccagag tagaagagga
    10321 aggtttcgag gaagacgctg gcaactttct tttcaagtgg gctgccgttt aggtagattt
    10381 cgttgacaat ctcagccttc ttttgtaggt aaggattggt attggtccat tcgaaaattt
    10441 cttcaatctc agccttagta ttcaaggtag aaaagattga tgagtaagat ttagcgtgga
    10501 cagattccat aaattggatg ttattgaaaa cagcttcctc atgtggtgta cggatgtctg
    10561 cgcgaagggc ttgaacccca gtttcagatt gcatagtgtc aagaagggtt aaaccaccaa
    10621 aaacttttcc gaccaagtct ttctctttgt tagatagctt tctccagtca tccaagtcgt
    10681 ttgataaggg aatacgtgta tcgagccaaa attgctccgt cagtttttcc caagttgatt
    10741 tgtcgatgac atcttcgatg gcattccagt taatggcttt gtagtaagtt tccatttaaa
    10801 atctctttct gtgtttagta ttgcgaactc acaattattt ctactttacc ataattctat
    10861 aggagtatcg cacaaaaagt cggaagcccg acttttaaaa tgttacataa attatgttat
    10921 gacatagtag atttgatttt atcagtgctg cttagggaaa aataatgttt ctatgctaga
    10981 aactaaatca cacagctttc acattggttg gcgccgactt ctccaccgtc atctgtaaag
    11041 gtacggacgt agtagataga cttgattccc ttgttaaagg catagttacg aaggatggac
    11101 aagtcacgtg tcgtttgttt attttccctc ttccattcgt aaaggccttt tggaatgtca
    11161 ctacgcatga agagggtgag tgaaagtcct tgatccacgt gttcagtcgc agcagcgtaa
    11221 acatcgatga ctttacgcat atccatatcg taggcagaag tgtagtaagg aatggtttct
    11281 gtagacaagc cagcagcagg gtagtagatt ttaccaattt tcttctcttg gcgttcttcg
    11341 atacgttgcg taatcgggtg gatagaagca gaaacgtcgt tgatatagct gatagaacca
    11401 tttggcgcta cagcaaggcg attttggtgg taaagaccat cttcttgaac cttgtcgcga
    11461 agttcagccc aatcagcaac accagggata aagacatttt tgaagagttc tttaacacgg
    11521 tctgatgttg gaacaaattc accagttaca tacttgtcaa agtaacttcc gttagcatag
    11581 tctgattttt caaagttgtg gaaggtaata ccacgttcac gcgcaatatt gtttgactct
    11641 accaaggtcc agtagttcat aagcataaag tagatgcttg taaattcaac agactcaggt
    11701 gaaccatatt caatgagttg ttgggcaagg tagctgtgca gtcccatggc accgagacca
    11761 aaggtgtggg cttggctatt tccatggtca atcgttggta cagctacgat atgtgaacta
    11821 tctgtaacga aagtaagggc acgaaccata gcacggatag aacgaccaaa atcaggtgaa
    11881 gtcatcatgt taaccacgtt ggttgaaccc aggttacatg aaacatctgt tcccatttga
    11941 aggaattctt gagcatcgtt gatcaagctt ggttcttgaa cttgaagaat ctcagaacac
    12001 aagttactca tgataatctt tccatcaaca ggatttgcac ggttagccgt atcgatgttg
    12061 actacataag gatagccaga ctcttgttgc aatttagaga tttcagtttc caaatcccgc
    12121 gccttgattt ttgtcttgcg aatatttgga tttgcgacca attcatcgta tttttcagta
    12181 atgtcgatgt aattgaatgg cacaccgtat tctttttcta cagagtaagg gctgaagagg
    12241 tacatttctt catttttacg agccaattcg tagaatttat caggtactac aacaccaagt
    12301 gatagagtct tgacacgtac tttttcatca gcgttttctt tcttagttga aaggaaagcg
    12361 atgatatctg ggtgaaagac gttgaggtag acaacaccgg caccttgacg ttgccccaat
    12421 tggttggagt aagagaagct gtcttcaaaa agcttcataa caggaacgac acctgaagca
    12481 gctccttcat agcctttgat aggtgcacca gcttcacgaa ggttgctgag ggtaattccc
    12541 acaccaccac caatacgtga aagttgaaga gctgagttga tagaacgtcc gatagagttc
    12601 atatcatccg tcacttggat taggaaacaa gataccaact ctccacggcg agcacgtcca
    12661 gcattcaaga aggaaggagt agcaggttgg tagcgttggt ggatgatttc attggcaata
    12721 tcgattgcaa cagcttcatt cccatcagcg aaataaaggg cgttgaagaa gacacggtct
    12781 tccatatttt caagatagta ttcaccgtca ttagtcttta aggcatattg attgtaaaat
    12841 ttataagctg ccatgaatga cttgaattgg aagttttggt ctttgataaa ttgagctaat
    12901 tcttccaaga actctggacg gtatttcttg ataaaggctg tttcgatgta gttgtgttca
    12961 atgaggtaat tgattttgtc tttgattgaa tcaaaaacca tagtgtttgg aactacattt
    13021 tctttaaaga aagcatccaa ggcttccttg tctttatgaa gcatgatttg tccattaaca
    13081 ggacggttaa tttcgttatt aagacggaag taagtcacgt cttcaagatg ttttaatccc
    13141 ataaaatttc ccttatctaa ttacaaaaga aaggcttcta agttagccct aaaagcagtt
    13201 tcttctggat gatgtactaa gattatgcta attgtttcag ttttcctggt tggaaacctg
    13261 aaaagacttc agttggtgtt tggataacag gagctgcgct aaaaccgagc tctttaactt
    13321 gatcgacgta ctcaggttgc tcatcaagat tgatttcacg ataagagaca ttattactgt
    13381 ccaagaaacg cttggtcatt ttacattgga cacaattgtt tttagaataa acggttacca
    13441 ttgtgtaact cctcttcaaa atttaatact atcttagtat atcagaaaat aaaattttgt
    13501 caatgatttg aactaaatat agtggtgttc ttttgttgtt tttatatata aacacaatat
    13561 atagtgtttg tattgtgaaa tagcaatgat tatcctataa attgttttta aagaaactat
    13621 atcctgtgtt ttgttatcta ggatagaaga ttttcagcaa gttatctgaa aggaaattga
    13681 aggaaaatcc agaaaatgct tgaaaaaaat cctagaagat ggtataatac taaattgtaa
    13741 gggttatcac atataactca aaaaaagaaa gaacaaaagg agagtcaaac tatggcttct
    13801 aaagatttcc acgtagtggc agaaacaggt attcacgcac gtccagcaac attgttggta
    13861 caaactgcta gcaaatttgc ttcagatatc actcttgagt acaaaggtaa atcagttaac
    13921 cttaaatcaa ttatgggtgt tatgagtctt ggtgttggcc aaggtgctga cgtaactatc
    13981 tcagctgaag gtgcagatgc agatgacgct atcgctgcaa tctcagaaac aatggaaaaa
    14041 gaaggattgg cataagggaa atgacagaaa tgcttaaagg aatcgcagca tctgacggtg
    14101 ttgcagttgc aaaagcatat ctactcgttc agccggattt gtcatttgag actattacag
    14161 tcgaagatac aaacgcagaa gaagctcgcc ttgatgccgc tctacaggca tcacaagacg
    14221 agctttctgt tattcgcgag aaagcagtag gtacgctcgg tgaagaagca gctcaagttt
    14281 ttgatgctca cttaatggtt cttgctgacc cagaaatgat cagccaaatc aaggaaacta
    14341 tccgtgcgaa gaaagtgaat gcagaagcag gtctgaaaga agttacagat atgtttatca
    14401 ctatctttga aggcatggaa gacaacccat acatgcaaga acgcgcagcg gatatccgcg
    14461 acgtgacaaa acgtgtattg gcaaaccttc ttggtaaaaa attgccaaac ccagcttcta
    14521 ttaatgaaga agtgattgtg attgcgcatg acttgacacc atctgataca gctcaattgg
    14581 acaaaaactt tgtaaaagct tttgtaacca acattggtgg acgtacaagc cactcagcta
    14641 tcatggcacg tacacttgaa attgctgctg tattaggtac aaataacatc actgaaatcg
    14701 ttaaagacgg tgacatcctt gctgttaacg ggatcactgg agaagtgatt atcaacccaa
    14761 cagatgaaca agcggcagaa tttaaagcag ctggtgaagc ctatgcgaaa caaaaagctg
    14821 aatgggcact tttgaaagat gctcaaacag tgactgctga cggtaaacac ttcgagttgg
    14881 ctgccaatat tggtactcca aaagacgttg aaggtgttaa caacaacggt gcagaagctg
    14941 ttggacttta ccgtacagag ttcttgtaca tggattctca agacttccca actgaagatg
    15001 agcagtatga agcatacaag gctgttcttg aaggaatgaa cggtaaacct gttgtcgttc
    15061 gtacaatgga tatcggtgga gataaggaac ttccttactt cgatatgcct cacgaaatga
    15121 acccattcct tggattccgt gctcttcgta tctctatctc tgagactgga gatgctatgt
    15181 tccgcacaca aatccgtgct cttcttcgtg cgtctgttca cggtcaattg cgtatcatgt
    15241 tcccaatggt tgcgctcttg aaagaattcc gtgcagcgaa agcagtcttt gatgaagaaa
    15301 aagcaaacct tcttgctgaa ggtgttgcag ttgcggataa catccaagtt ggtatcatga
    15361 tcgagattcc tgcagcggct atgcttgcag accaatttgc taaagaagtt gacttcttct
    15421 caattggtac aaacgacttg atccaatata caatggcagc agaccgtatg aacgaacaag
    15481 tttcatacct ttaccaacca tacaacccat caatcctacg cttgattaac aatgtgatca
    15541 aagcagctca cgctgaaggt aaatgggctg gtatgtgtgg tgagatggct ggtgaccaac
    15601 aagctgttcc acttcttgtc ggaatgggct tggatgagtt ctctatgtca gcaacatctg
    15661 tacttcgtac acgcagcttg atgaagaaac tcgacacagc taagatggaa gagtacgcaa
    15721 accgtgccct tacagaatgc tcaacaatgg aagaagttct tgaacttcaa aaagaatacg
    15781 ttaattttga ttaatcgaaa agtccctgca actcagttac agggactttt tttgatattt
    15841 taaaaagaat tttcaagaaa atctttctta taaaaagtcc aaccttgaaa aagtagtggt
    15901 cagaacaaaa aatacttaaa tggttcataa aattcttgac aagttggaga tttaggagta
    15961 aactattaac cagttaagta atagagagga gtttctgcaa tttagaaatg aattgcaact
    16021 agaaatatca aatagaaaga gagtttcgat gaaaattaat aagaaatacc ttgttggttc
    16081 tgcggcagct ttgattttaa gtgtttgttc ttacgagttg ggactgtatc aagctagaac
    16141 ggttaaggaa aataatcgtg tttcctatat agatggaaaa caagcgacgc aaaaaacgga
    16201 gaatttgact cctgatgagg ttagcaagcg tgaaggaatc aatgctgagc aaatcgtcat
    16261 caagataaca gaccaaggct atgtcacttc acatggcgac cactatcatt attacaatgg
    16321 taaggttcct tatgatgcga ttttcagtga agaattactc atgaaagatc caaactataa
    16381 gctaaaagat gaggatattg ttaatgaggt caagggtgga tatgttatca aggtagatgg
    16441 aaaatactat gtttacctta aggatgctgc ccacgcggat aacgtccgta caaaagagga
    16501 aatcaatcga caaaaacaag aacatagtca acatcgtgaa ggtgggactc caagaaacga
    16561 tggtgctgtt gccttggcac gttcgcaagg acgctatact acagatgatg gttatatctt
    16621 taatgcttct gatatcatag aggatactgg tgatgcttat atcgttcctc atggagatca
    16681 ttaccattac attcctaaga atgagttatc agctagcgag tt
//
LOCUS       DAVBCA010000049        16462 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.049, whole genome shotgun sequence.
ACCESSION   DAVBCA010000049 DAVBCA010000000
VERSION     DAVBCA010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16462
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.049"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..231)
                     /locus_tag="VQU19_001569"
     CDS             complement(<1..231)
                     /locus_tag="VQU19_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2480799.1"
                     /translation="MTIEPGQRIALVGQSGSGKSTLSKILSGLYKIDTGKILFDGVNI
                     NQIDKKILSQNLGVVPQDSFLLNRSILDNITLK"
     gene            complement(400..1713)
                     /locus_tag="VQU19_001570"
     CDS             complement(400..1713)
                     /locus_tag="VQU19_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000197307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2480800.1"
                     /translation="MTRKVPNIEQMSQIECGLCCCLSILHFYKSKETLLDLRRDIEKG
                     RDGYSIGDLKQLLNKRNFDTGSYQVKDVNKISELPLPLIAFWDNQHYVVIYKVKKNKV
                     YIMDPSKGYINYEFKEFSKHFSNIVLLSFPNENYQSLKSQFPSPWIRVFSSFSKVKGR
                     LILTLLFSIISYLIILSVPVMTSKFINSALGNTFSFQTSFLILFSLLCLYLISILARS
                     MGILFSNIFFSRDIESFTFKHLLKLPYSFFELRAKGDILYRISSLSGFRELFTNQVVG
                     GVVDIGTILSVVIYMFLSSKTLSIIALILSLINFLFLFSTRKIMYDTVNRELQEQSLI
                     YSVETEALNTISSIKISGLEDEIYENWSKYLKNVLTKYKKRSIVHILYNSATNVFQLF
                     APIIILIFGLDNVLNGKILLGEVVAFQTMASILFSSEISIFNAYT"
     gene            complement(1706..2254)
                     /locus_tag="VQU19_001571"
                     /pseudo
     CDS             complement(1706..2254)
                     /locus_tag="VQU19_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000059560.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(2335..2397)
                     /locus_tag="VQU19_001572"
     CDS             complement(2335..2397)
                     /locus_tag="VQU19_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHP2/SHP3 family peptide pheromone"
                     /protein_id="HET2480801.1"
                     /translation="MKKISKFLPILVLVMDIIII"
     gene            complement(2566..3554)
                     /locus_tag="VQU19_001573"
                     /pseudo
     CDS             complement(2566..3554)
                     /locus_tag="VQU19_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050775.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            complement(3503..4630)
                     /locus_tag="VQU19_001574"
                     /pseudo
     CDS             complement(3503..4630)
                     /locus_tag="VQU19_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423473.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha amylase N-terminal ig-like
                     domain-containing protein"
     gene            complement(4793..5677)
                     /locus_tag="VQU19_001575"
     CDS             complement(4793..5677)
                     /locus_tag="VQU19_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HET2480802.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            complement(5789..6643)
                     /locus_tag="VQU19_001576"
     CDS             complement(5789..6643)
                     /locus_tag="VQU19_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HET2480803.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGIWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNLTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCNIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            complement(6701..7459)
                     /locus_tag="VQU19_001577"
     CDS             complement(6701..7459)
                     /locus_tag="VQU19_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HET2480804.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEVILYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVYDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYALS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVVF"
     gene            complement(7521..7709)
                     /locus_tag="VQU19_001578"
     CDS             complement(7521..7709)
                     /locus_tag="VQU19_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HET2480805.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            complement(8031..8597)
                     /locus_tag="VQU19_001579"
     CDS             complement(8031..8597)
                     /locus_tag="VQU19_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480806.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKTYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            complement(8865..10544)
                     /locus_tag="VQU19_001580"
     CDS             complement(8865..10544)
                     /locus_tag="VQU19_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HET2480807.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIEGYSLEAQKSRMKAFAIYNDYEIV
                     GEYEDAGKSGKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIM
                     QDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRIQTMEGRIQKAREGKWNG
                     GFAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAI
                     VSDEVWQAAQVKLKSQAKKYEHVNKGKDTRTHLLSGIVKCPICGVGMFGNKCIKKKKD
                     GTKYKDFYYYGCNHRQMIRGHKCTFSKQIREELLDDAVAEVIVKIVSNPKFASMMQEK
                     INMKVDTSEIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLYR
                     MYDKVDELESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLISAL
                     ISEIQVYEEKQSNGQWLKSITFKLPIIEENLNIGLDNDEQVECVSLLEKRS"
     gene            complement(10636..10797)
                     /locus_tag="VQU19_001581"
     CDS             complement(10636..10797)
                     /locus_tag="VQU19_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480808.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            complement(11481..11795)
                     /locus_tag="VQU19_001582"
     CDS             complement(11481..11795)
                     /locus_tag="VQU19_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480809.1"
                     /translation="MGITWKDIEIDKEREGEIDKKSTPIFYGEFKNVRLSKEEYKNLK
                     EKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWYEEDKDKLRQKGLNKKMNYDVGE
                     SL"
     gene            complement(11761..12150)
                     /locus_tag="VQU19_001583"
     CDS             complement(11761..12150)
                     /locus_tag="VQU19_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET2480810.1"
                     /translation="MPKRYLLDGKTPRISATNIDNGILGYYEDIDDKNYRVFENFISV
                     SFLGAVFYHKYKASLDMKIHCLKLKNKELNKEVAFYLTSIIRQALKNTEYKDQISSTV
                     LPDIKIKLPIDSRGTPDWNYMERYRDR"
     gene            complement(12538..13332)
                     /locus_tag="VQU19_001584"
     CDS             complement(12538..13332)
                     /locus_tag="VQU19_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2480811.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVSS"
     gene            complement(13332..14339)
                     /locus_tag="VQU19_001585"
     CDS             complement(13332..14339)
                     /locus_tag="VQU19_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET2480812.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRN
                     I"
     gene            complement(14339..15346)
                     /locus_tag="VQU19_001586"
     CDS             complement(14339..15346)
                     /locus_tag="VQU19_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET2480813.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLATFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            complement(15336..16361)
                     /locus_tag="VQU19_001587"
     CDS             complement(15336..16361)
                     /locus_tag="VQU19_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HET2480814.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVISDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
BASE COUNT         5165 a         3100 c         2225 g         5972 t
ORIGIN      
        1 ctttaaagtt atattatcaa gaatacttcg gttcaataaa aatgaatcct gtggaactac
       61 tcctaaattt tgacttaata tttttttatc tatttgatta atatttacac catcaaataa
      121 aatttttcct gtatcaatct tatataatcc tgatagtatt tttgataacg tactttttcc
      181 tgaccccgat tgaccgacta gtgcaattct ctgtcctggc tcaatagtca aatttaaatt
      241 ttctattaca ggagctgagt ctttggaata agagaaagat aggtccttaa tatctattct
      301 accttctaaa gaacactttt taagaccatt ttcaacattc tcttcatttt caagccagat
      361 atcatttact ctatttaagt atcctgctgc caaaatatac tacgtataag cattaaatat
      421 tgagatttct gaactaaata aaattgatgc catcgtttga aatgcgacaa cctcacccaa
      481 taaaattttt ccatttaaaa cattatcaag tccaaaaatc aatataatta taggagcgaa
      541 caattgaaat acattagtag ctgaattgta taaaatatgc acaatacttc gttttttata
      601 ctttgtcaat acgtttttta aatacttaga ccagttttca tatatttcat cttctaatcc
      661 cgatattttt attgaagaaa tagtatttaa tgcttctgtt tctactgagt aaatcaatga
      721 ttgttcttgt aattctctat taaccgtatc atacattatt tttctagtac taaacagaaa
      781 caaaaaattg attaaactca atataagagc tataattgat aatgtttttg aactaagaaa
      841 catatatatt acaacactta gaatagtccc gatatctact actcccccaa caacttggtt
      901 agtaaatagc tccctaaaac cactaagact agaaattctg tataaaatat ctccttttgc
      961 cctgagttca aaaaaactat atggtagttt aagcaaatgc ttaaatgtaa aactttcaat
     1021 atctctacta aaaaatatat tagaaaatag aattcccata ctcctagcca agatagaaat
     1081 aaggtacaaa caaagtagag aaaataaaat taaaaacgag gtttgaaaag aaaatgtatt
     1141 ccctaatgca gaattaataa actttgaagt cattactggt acggaaagta ttattaagta
     1201 acttattatt gaaaatagta acgtcaaaat caatcgacct tttacctttg aaaaactaga
     1261 gaatactctt atccatggag aaggaaactg cgacttcaaa gattgataat tttcgttagg
     1321 aaatgatagc agtactatat tactaaaatg ttttgaaaac tccttaaact cataatttat
     1381 atatccttta gaaggatcca ttatatagac cttattcttt tttactttgt aaataactac
     1441 ataatgttga ttatcccaga atgctattaa tggtaacgga agttcactaa ttttatttac
     1501 atctttaact tgatatgagc cagtatcaaa atttcgttta ttcaataact gtttcaagtc
     1561 acctatacta taaccatctc tccctttttc tatatcacgt cttaaatcta gtaatgtctc
     1621 tttgctttta tagaaatgta gtatggacaa gcagcaacat aaaccacatt ctatttgaga
     1681 catttgctca atattaggta cttttctagt catcatgtcc tcttaactcc agtaataaaa
     1741 cattaagtaa tctatcatct tgttttcgag atatttcata gacaactcca gatactccta
     1801 gcataaaaga aaatgtattc atagtattca aatccgtact taattctggt ttgataacct
     1861 gagaaacgac attatcaaaa taaaaatcta tagattcttt tattaatagg ttttcttcat
     1921 ctttcaatat tgcatcaaga caactgatag tacctacaga accgtgacat aaattcaatt
     1981 ctcttatttt ttctacatta gttaatacat tttcaattat tgataaatca ttattcccaa
     2041 tattagtttt atcgaaaatt tcttttctag ctaataaaat gcccggagct ccataacacc
     2101 aaaaattagg aaaggaatca ttatgatttc ttcatatgtc tttccaattt tttaatatat
     2161 tattgaaaca tttatcttct ttatatagta attcctctat acattttaat atatctgtac
     2221 taggattaat ttcataataa tatgataatt acattgctac tccagaataa tcgtgtgcta
     2281 aacctgttac tgttatatta tctaattgtg aaatacaata attaatacac ttttttaaat
     2341 gatgataata tccatcacca aaaccaaaat cggtaaaaat tttgaaattt tcttcatact
     2401 tggacttcct ttccgttttt atttattgta caataaataa aaacggattt aatttttgtt
     2461 gggaaaatgg gaaattatga aatcaaaact tggcatcaca cttagaaaag ttcgtaaagg
     2521 aaaacaaatt agtctatgct ctgtagcaga tgaacatctt tcaaaatcac aaatatctcg
     2581 ttttgaacgt ggggagtcag agatatcttg tattcgacta atcaatattt tagacaaatt
     2641 acatattact ttgtagggga gtttttggct atcgttgctc aattgtctga ttaaggtcct
     2701 acccttgatg aaacaattat tatccatgtt ttctttatta tagacaaagt aagaagacgt
     2761 ttctcgaatg tagactttat attttttatg attttcttct tccataatat ccaattgata
     2821 gttgggaatg aaaataagac cgctctgttt gacaccgaaa gacaccttga tatagacgcc
     2881 cttatcaact agcttctcta tttggttctc tgcaagttcc acttcaaatt cacgaacggt
     2941 atctcatttt tccttaaatg tcttaaaggc ttcctcaatc tcttcagtgg atactttatc
     3001 cttatctcgt tcttcttgga aagcatggta ctgttcctgt aaattctcta atccttctga
     3061 agcaacgact tccttatttt taaaataatc ttgaaaaaat ttgacatcat ataatttctt
     3121 atcacttatt ttttgatgac ccaaacttat cttttgatta ttttcttcca ggataaaagt
     3181 tacatttttt gttttaagtc aatggttaga ttcaattctt ttgcttttgt tattaaatct
     3241 tctaaagaat tgacacggtt taacaaaaat tctaaacgac tttcaatctc ttgcttagca
     3301 aaatgcgttc taaaaaattc ttcatcatat agatctcgtt tgctgagttg gcgccctcga
     3361 attggtttta tcatcgttct atctgtcatc aaaaaacggc tatgcttttg actaaaatca
     3421 atctgaacat gcaactgctt tgctttctct aaaaaatcat caaacgattt agattgctga
     3481 agcaaaaaat aaagacgttg tttcaattca aatttatgac tagattcctt atatttttta
     3541 taatctcgaa aagatcagga tttttagcta aaactgcctt acgaaaatcc ttccagaact
     3601 gatggtcaat ctcattagcc acatccaaac gccaagcatc gatattaaac tcttcaatcc
     3661 aataagtcgc aacctttaaa agataattct tgacctctgg attggctgta tttagcttag
     3721 gcatatagtc ctcgaaacca aaaacatgat agggtaagtc tctcttatta actagctttt
     3781 cagttgtcaa tgggaattgt tgaatatgga accaatcctt ataagcagac tgttcaccat
     3841 ttttgacgac attttttcat tgaagagatt gcgaaccaat atgattaaat accgcatcca
     3901 gcatgacttt catgccacga tgatgcgctt gatccaccag ttcccgaaag gtctccttgt
     3961 ctccaaaata acggtcaatt tcaaagtaat ctgtcgtatt gtacttgtga ttacttgtag
     4021 attcaaagat gggacaaaga tatagtccag taatacccaa gtcttgcaag taattcatat
     4081 gatcaataat cccctgtaaa tcaccaccaa agaaatcatc gctcttaggt gtgacagatg
     4141 aatcccagtc taaagtccct tctgggttta atagagcatt gccattggca aatctttcag
     4201 gaaatatctg ataccatacc gtatttgaaa cccagtcagg aaccttgcag gcatcaatct
     4261 catgaagata aggcaactta aatccattcc caattgcatg aagattttct agagaatttt
     4321 ccacacaccc tttatcgcca tacaaaatat tttgaccttc tgtatctctg agctcaaaga
     4381 gatactggat acgtgcaaag tcaactgaca cttcaacctg ccaatggtca aataaggtac
     4441 cagaagttat cttgaccatt tcttttgtat cctgataaaa ctcttccata aagataaaag
     4501 ggtccccata gtgcaagttg atgctttcaa tgtccccttt cttagttcga attcgaatat
     4561 ggagtttctt atccttataa agataggcat actccgactc aggcctatgg taaatagcac
     4621 tcaattccat caatttgtct cctaaagtat tcattcaaat tttacgcaaa cgttttcaaa
     4681 ctcaataaat ccagtatact atttttgtaa actatttgca aggaatgtcc gttgttaaag
     4741 gaactatctt ttaaagtata caaaaagcct taaaaaaggc tttctctata tactaatcct
     4801 ctttcggttt tgaaaatact tctactcgct gagctaggac tttgatttct acaggtaggt
     4861 tatctgattt atctccgtca acatctgact ccaattcact atctgaagag attttaatat
     4921 tacgcgcttt gatatactcg atattatcat ttgcgacaac atcccctttt aataaatcag
     4981 gaatgacgga taatttggag aatatagagg catctttcag aatcaaaatg ttggcatagc
     5041 cgtccttgtt ttcttcaaag attttcttat cagcgaagta atttgtcaaa aggaccaaaa
     5101 catggctagc ttcaccaaca taatttccat tttctgtctc aaccttaatg ttaaagacct
     5161 gatctgtcat gacagacttc atggtattta cagcataggt taaaataccg aattttgttt
     5221 tgtcctctat ttcaacattg tgaatcgcct caggcagaga accgatacta aagatataac
     5281 caaaatagtt gtcatttgct ttaccgatat caatcttatt ggttaaatca aaatccagtt
     5341 cgtcaattgc gccatcgatg tcttgattga tttccaaaag ttttgtaatg aggttacccg
     5401 taccgcctgg gataatccct aacttaggaa tgtagtctct ctcatcaata cctgaaatga
     5461 cttcattgac agttccatct ccaccaaaca caaccactgc atcatactgc tcacgagaag
     5521 cttcttcagc aaaatgtgtt gcatccagcg ctttttcggt aattttggtt tcaacatatt
     5581 caaagtattc ttttgcttta ttctccagct tttctttgta atccaaagcc ttctcgccac
     5641 cagaagtagg gttgataatt accattgctt ttttcattga ttttatcctt aattttaaac
     5701 agaaatgttt acatttcgtc gtatgcaagt aaatgtaatc ctattataca atgaaaatac
     5761 agaaaagaga aatctgacgt actggagatt aatacgcttt tattctattt tcccatcgcc
     5821 taactacatc ctttaagggt tcatccaagt aagaataggc cttatccttg atccaatcag
     5881 gaataccgta agctgcctct gctatgttac aagtgattgc tgcgagagta tcactgtcgc
     5941 caccaagtga gatggcattt cttatcgcat cttcgaagtc tctactttca agaaaggcga
     6001 taatggcttg agggacagtt tcctgacatg tttcgttaaa acgatagtta ggacggattt
     6061 catctaaagt ttgagataga ttgtaatcgt attctttttc tatataatcc ttaattcgtc
     6121 ttttacactc tgtaagattg tcgttaattg attgctcgta ctctctacaa taaccaccaa
     6181 agtaaaaacg acatagaaag atagcatcag ctgtagccat agcgcctttg acaccttctg
     6241 gatgattatg agttacctct gcagaaagac tcgtaagtcc tctagatgat ggccatatac
     6301 cagttttcgc ataaaaacca cagtccatga tccaagcaca tggagaaata cgcatagctg
     6361 atccattccc aaagctatta taaggctcac ggttatcgct gtttagccat gcattaaacc
     6421 gagcaccgta atcagcattc ggatacattc tgccatattt cttcatcgcg tcaatgaaat
     6481 cgtctttttg tccaccattc ataattgctt ctgcaacagc acaggtcata accgtgtcat
     6541 ctgtaaaaaa gcagtccttc cgaaataaag gaaagtcctt tgttttgata ttgttccatt
     6601 cgtaaacaga accgacaata tctccaataa ttgctccaag catcagattc ctccttgttc
     6661 attttgatgc tttttatatt ggttatatac catatttatt ttagaaaaca acatcctgtt
     6721 ggattttaaa aatttcattt ttttcaaaat agggttttac catttctttc cacctagctc
     6781 tatgaaaatt gattgatttt aaaggagata gggcataatt tcccaatgca taaccatcat
     6841 ttacttcaac aacaagtgtt ctgccatcgc gagtaacacc gatatctagt ccataagcta
     6901 ttggcgcatc tttccaacat gatatcgctt catcaattac acttgcatca aattgtgcat
     6961 gataatcacc tgtatagggt cgaacatcta atacgcgacc atctaacaca aaacaacgcc
     7021 attcagctat gaattctaca acctcactaa tccatatagg atagtcgaaa ggtagaccaa
     7081 tacctattaa atcatgggtt ccattaacaa ctcttccagt aaagactttt gaaccagctt
     7141 taggcttaat aaattttccc caattatcag gtatattcac aatctctcct aaaataccag
     7201 cataaatctt tcgaccataa aactctttaa gctcaatagg atagtcataa accggaacgt
     7261 ttaagcccat catttttagt aatgctctag tctccattat ataatctaca actatatctt
     7321 cacttgttaa ctcttttatt tcagaaaaag attgatataa aataacttct tctccttgta
     7381 agtaggcacc tacttgagca ttgtatttat taattgaaac ctcacttggt aatttacttt
     7441 gtctaatata aacaaccatt tcatcactcc tatatcacta gtgttacact gatttgtaaa
     7501 aaataatagc aattttgctc ttattttttt gagtaaatag ctcccataat atcatcgaaa
     7561 taatcaacgg tatttaggag taattcaata acctgggact ttgttagtcg cattcccctt
     7621 ctatctctag catcttctac taaattttca agtttctcta gatttttatc atccaagcta
     7681 atcattattc tatttttatc ggttgccatt ttcatcacct caagttaatt ctatcacagg
     7741 tgtaacactt gtgtcaactg gcttttataa tacattagtt taaaagtgga gaggattttt
     7801 aacacagtaa ctttaaatct ttggtattaa aaaattttca caatatttat agaaataaaa
     7861 tctgtctcaa atcagttatc aaatctagta taaattatga gcggctactc taatactttc
     7921 cctctaaaca agaaaaagac ttacactcaa ggattttctt cccccccttc gttataacgt
     7981 tttgactctt ttactagcaa aggtatatac tcacaaggaa ctttggttga ctattgaatc
     8041 tctccaactt cttctttaac atatccttct acatcttcaa tctctacaaa cattgggtct
     8101 aagtgacaca agaaatgcca aacttcgatc cctttttttc tgtaaagaat cgcttcaccg
     8161 tcttcacttc cgaaaaagct tctgtcgatt tcatatccgc ggctttctaa gaagtctttt
     8221 gctttacgat agttcgtttc tcttgtttcg acataggttt taacttcatg gttgttaacg
     8281 acatatgcat caatttttga atatccttcg atcactctat catttttgag ggataaattt
     8341 gaaatctctt tccaaataat gtttacattt tcctcaggat cgaacataaa tttagataaa
     8401 ggaacaatat ttccgttaaa aataatttcc atataatccg gtatgttttt aggattaaaa
     8461 tactccactt caaaaccatc ttctgtttcc agagtgtatc ccgggatttg agctacaaag
     8521 gctttcccat cttctatgga atcaaatgct actaaatctt tagaataatc attttggtac
     8581 aattccaata taaccatcga taatctctcc attttcatta tcaggctaat gtaaataagc
     8641 acgtcacctg accaattcag gctctctgta tcatctcatc atatttccta cttactttac
     8701 gagtcctata cccagaacac accttatcga ccttcggtct cacctcgttg cattggctga
     8761 acatctactt ttacttcgct gatgcttcaa ctcgtacaag cagtgatacc gcctcagcgt
     8821 gatgcgtcag tgggactcaa aaggttcggg gaaccttttg aggattaact acgtttctct
     8881 aataaactta cacattcaac ttgttcatca ttgtccaaac ctatgttgag attttcttct
     8941 ataattggta gcttaaaagt aatggatttt agccattgtc cgttagattg tttttcttca
     9001 taaacttgaa tttcagaaat caaagctgaa attaactgcc tacgctctac atcattcatg
     9061 actttataga gcttatcaaa atagatcaga accttatata tgttatctcc tgtaagcttt
     9121 tcagcttcaa tagtctgttt ctttgctttc gcatcaatta gtgatgattc taattcatct
     9181 actttgtcat acatacgata tagtctatca tctaaatcct gtttccttct cttataatgc
     9241 ttatcttcaa catctaaatt atctatttcc tcaattagct taaactttgt agaatgactc
     9301 tttctcaatt ccttttggta attatctatt tctttttcta tttcagaggt atccaccttc
     9361 atgttgattt tttcttgcat catagaagca aatttcggat tacttactat cttgacaatc
     9421 acctctgcaa cagcatcatc taacaattct tctctaattt gcttactgaa tgtacactta
     9481 tgacctctta tcatctgcct atggttacaa ccatagtaat aaaaatcttt atactttgtg
     9541 ccatctttct ttttcttgat acacttgttc ccaaacattc ccactccaca tatcgggcat
     9601 tttacaattc cagaaagcaa gtgtgtgcgt gtatcttttc ctttattcac atgctcatat
     9661 ttctttgctt gagattttag cttaacctga gcagcttgcc aaacttcatc ggaaactata
     9721 gcttcatgta tcccttcaga tattagatat tcatcttgtt caacctgctt atattcattt
     9781 cttgtaccat gaactttttc taaagttctt cttccaaatg ctattttccc attatataca
     9841 ggattcttta atatctttct tataagacct gcatcaaaca aaggattctt accattctgt
     9901 cttgggattt ttctaattcc atgattctct aagtatttag atatcccatt ggctcctatc
     9961 gtagtattta catactggtc gaaaatcgtt cttattgcaa ctgcctcttc ctcatttata
    10021 aacagcttgc cgtcttcaag tttatatcca tacggagcaa agccaccatt ccattttcct
    10081 tcccttgctt tttgaatgcg accttccatt gtttgaatac ggatgttttc tctttctatt
    10141 tcagccacag ctgataaaac agaaatcatt agtttcccag catctttaga tgaatcaatg
    10201 ccatcttcaa cgcagataag attaactcca taatcctgca ttatctgaag tgtagaaaga
    10261 acatcagcgg catttcttgc aaatcttgat aacttaaaca caagaacaaa agatactcca
    10321 tcttttccag attttatatc ttccatcatt cgattgaact gtattctacc ttcaatagac
    10381 ttgccagact tcccggcatc ttcatactct ccaacaattt cataatcgtt gtaaatagca
    10441 aaagctttca ttcgtgattt ttgtgcctct aacgaatacc cctctatctg tattgacgta
    10501 gatactcgtg tatagaggta tacttttatt ttttcttttg acatagtatt aatctcaata
    10561 taatttttct atatcatata taattttttt aatttaagtt tggactatca tttcaagtat
    10621 attataacac ttttattagt ccgtctcaat ttgtgttttt gccatgtcaa aactattttt
    10681 catctcttga ttttttgctg gcgttggatc gggtagatta tctaaatcta aagcaccagc
    10741 atattttgca atcagatttg ctattaaatc agccaatcca ttccagtcat tgtccaatat
    10801 atacctcctc taaagtttta tatctaataa ttatttgttt aattaagttt tttgacattg
    10861 acaagtgctt tggattagca acataggaat ctcacctccg cctctattcc ggatgagccg
    10921 gcttcaacct tagaagtatc attatcctca ttttcttcat agcggatagg gtatccctcc
    10981 ctatattcaa actcttactt atcgctcact ttctttttac ttagcagaac tttttttgcc
    11041 gaattattca gccgaaagat cttgacggat aggttattac gctccaaaaa taattaacgt
    11101 cttgtcttgg tctattcaat tgttaaggtt caaaatttat cgagagttat taatcttttt
    11161 aaaatttgac catcagaaaa tatttatctt aatgtaacaa aattctataa attaccctct
    11221 tatacttaac agtgaaaaga agtctttctt ggtaaccaat tttgaaatag aatttgctta
    11281 tataaaaagg tcaaattccc actgcataag tagcagtgaa aattagaccc tcttggtaac
    11341 tgtcatctaa aagtcttcta gcatttcttt aattttctaa tcgcctttaa agtgtcatat
    11401 ttatattttt ttatctctgg catactttga taccttttta gacttaaagt ctttaatagt
    11461 gcctttccac ctctttttat ctataaagat tctcctacat cataattcat ttttttattt
    11521 aaacctttct gtcttagttt gtctttatct tcttcatacc attttaagat tgtcacatag
    11581 tggttttgat aggtcttacc actgctttcc atgtatctgg atagtttatt tatcattata
    11641 tctgtgtgtg agtttaattt ttcttttaga tttttatatt cttctttgct taaccttaca
    11701 tttttgaatt ctccataaaa aatgggggtg gactttttat ctatctctcc ctctctctct
    11761 ttatctatct ctatatcttt ccatgtaatt ccaatctgga gtacctctac tgtctatcgg
    11821 taatttaatt ttgatatctg gcaatactgt gctagatatt tgatctttat attcagtatt
    11881 ttttaaagct tgcctaataa ttgaagttaa atagaatgct acttctttat tcaattcttt
    11941 attttttaat tttaaacaat gaattttcat atctaggctt gctttatatt tatgataaaa
    12001 gactgctcct aaaaatgaaa cagatataaa attttcaaaa actctataat ttttatcatc
    12061 tatatcttcg tagtaaccta agataccatt gtcaatattt gtagcactaa ttctaggagt
    12121 ttttccatcg agtaaatatc tttttggaat agatgagcct gttggtactt gactcgattt
    12181 cccctttttt tcggtaataa atatttcttt ttattttgtt gtctgatatt tttcctacct
    12241 gtcctttgta ggatgagtat tttctagatt ttcttgaata actttttact tgaagtttta
    12301 gcttttgaac tagtcgttgt actttctttt tgtttattat cagtcctgat ctttttaata
    12361 ttgctgttat tctctatatc ctatttttca ttcatgatat tcttttacta attttatctt
    12421 aaattctgtg ctgtatttgc cattaaaaaa ctgacctcct ttagttagtt ttttggccta
    12481 acttttgagg gtcagttcaa aatttgcgac ttttaaatga attccaatat tcaattatta
    12541 agagctaaca tggtgcttgc caataggaat cattagaggc gaattggaaa tagggtcacg
    12601 tataattttt gcttcaagat taaagatatc tttaactagt ttatcattta gtatatcttc
    12661 aggctttccc tctgcaacaa gtttaccttc tttaattgca aataggtaat cagcgtatct
    12721 tgctgttaga tttatatcgt gcaaaatcat gcaaatggtt gtcttatatt tttggtttag
    12781 atcagtcaag aggtctaata gttctatttg atatgagata tccaagtaag tagttggctc
    12841 atctaaaagt aggatacttg tatcttgggc tagggctaga gctatccata ctctttgcct
    12901 ttgaccccca gaaagttctt caactaggtt atttgctaga tcttcaacat tggccttaac
    12961 cattgatctg tttattattt caaggtcatc ttttccaaga ctcttaaaag gctttctgta
    13021 ggggaaacga ccacggctta caagatcagc tactgttatt gattcaggga ttattggaga
    13081 ttgaggtaat atagctatgt gttttgctaa atctttttct ttataagaat taattgattt
    13141 attatcaagc aatacttctc cctctaatgg ctttataagt cgagacaagg ttttaatgag
    13201 tgttgatttc ccacaaccat ttgacccaat aataactgat attttttctt caggtatttt
    13261 tatatttata ttttccaaga ttattttttc atcataaccg caggtaagat tatttgacca
    13321 cagacctttc attatatatt cctcctgttc atttttatta gtaagtatat taagtatggt
    13381 gaacctaaca agccagttac aacacctact ggatatctag ctggtaaaat attttgagag
    13441 aatatgtctg ataacaaaac tagtaaaatt ccaaccaatc cagctaatat tgggcttctt
    13501 ttcttgccaa tatttaaggc tatgggacca gctaaaaaag atatacaagc tattggtcct
    13561 gtaattgaag tagaaaaagc agttaaagat acagcgcaaa aaattaaaac aagccttgaa
    13621 agctcgggat ttgctccaag tccgattgct atttcttcac caagttcaat aatttctagt
    13681 cttttattaa aaaataaaac taatatagta gcaataatac ttactattag aacaagaggt
    13741 atgtcatcta actttgtaaa agataaagag ccactgagcc atctcataac ttcttgtaat
    13801 tcatatcttg ctactttcaa caataaaaat gaggtgcctg ctcttgtgac agcttgaaaa
    13861 ccaataccta atattatcag tcttgctgct gaaaaaccat cttttttagc tagtaaaaat
    13921 aatattaaag atgatgttag tccacaagtt attgaaataa ttccagtagt taaactattt
    13981 gtttttaata ccaatatgca aaagaccgct gcaatagatg aagaacttgt gacaccgatt
    14041 atatcaggac ttgcaagagg atttcttaac atagtttgaa agataaatcc tgccaatcca
    14101 aaagaccagc cagctataat tcctgctaat aattttggta atctaatttc cataatcgaa
    14161 aaactagctc caggaacagt ttcactattt aagactttaa tcaaagttga aaaagaataa
    14221 ctttcatctc cgataagtaa aatgaaaaat gatagactga ttattattaa taaaaatagt
    14281 gaggaaaata gtgttattct attttttctt ttttgaatac ctataattaa attttgcatt
    14341 agttattaac ccctctattt ttcatagtta cataaataag tactggaccc ccgattattg
    14401 cagtaattat ccctacttca atttcacctg gtttacctaa catacggccg attatatcac
    14461 atataagcaa gagctctgca cctataaaag atgaagaaat ggtcattgtg cgtatatctt
    14521 tgcttataaa taagccacaa aagtgaggaa ctataagacc tacgaagcca ataggtccac
    14581 caattgcagt aatacttgaa cataaaagca cacttgcaat tattgcaagt gatcttatcc
    14641 tattaacatt aactccaaga ccaacagcca tttcatcacc catagctaaa gcgtttaaat
    14701 ctgatgaaat aaatatagct atcaagtgac ctaaaattat aaaaggtagt agtgtagata
    14761 tagaagataa tgtagctgct ccaaggctac ctatttgcca aaatctaaat ttgtctaaga
    14821 cgttattatt cggtaaaatt aaaaaactta caaaactgct taaagccata ctaacacaag
    14881 ttcctgataa ggctagtttt ataggggtaa ggcctgcttt tccgcttaca gcaatcgcgt
    14941 atacaaaaat tgcacttact aagccaccaa tgattgcaaa acttatatgg cttatgcttg
    15001 atgaaattcc taaaaaagaa agaccaatta ctacactaag acttgctcct gtgtttatac
    15061 cgagtatacc tggatcagct attgggtttc tagtaactga ttgcatcaat acaccgctta
    15121 tggcaagact agaacctgct aaaattgcaa aaatagttct aggtattctt ttatatataa
    15181 ttgatttaat aaaatcatca tttgtattgc ccattccaaa agttgctaaa aaatctctga
    15241 tattaatttc ttttgttcca agctttaatg acaaaaatat tgtaataaga agacctaggc
    15301 agattacaaa aattatgcct aggtttattt gttttttatt tcgcattttt gcatgcattt
    15361 cctaaaagat ttaggtattc ttcaatagta tagtttattg aaagtggtgt tggagtgcat
    15421 gaggctgcta acggtgtatt atctgaaatt acagcaacgg caccattttt aattgcattt
    15481 attttaccta aaagaggatc tttttgtaaa gcttcaagag ttttatcatc accataagtt
    15541 atgattacat cagcatcatt tatcttattt gcttcttctg cagaaatttc ctttgcaaaa
    15601 ctatcttcac tctcaaattc ttttaatgat tcagggaaaa ctagacctaa atctgttaaa
    15661 taatttgctc ttggatcttt gctagtataa atccagaatt ttgatgtatc tgcagcatta
    15721 atcatagtaa ataatacttt ttttcctttg atttttcctt tgatttctgg atgtttttct
    15781 aattctttgg atatacgagc ttcagtattt ttgattaact catcaccttc tttttccata
    15841 cctaaggctt ttgaatcaat tttaatcata tctctccata aagtttgcca aggtttagat
    15901 ttgtatgctg ctacaggagc aatttttgat agagtgtcat aatcttcttt agttatacca
    15961 gaataacctg ctaagataac atctggttta gaatttgata ttgcttcaaa gttaagtcca
    16021 tccaaatcgt caaataggtt agctttacca tttagttctt tgattttttc ttctgtccat
    16081 ggtaaaactc ctttatcagc acttacaccg taatttgctt ttgaaaatcc aacaggaact
    16141 attcctaaag ctaatgctac atcatgattt ccccaagcaa tagttgcaac tctttcaggt
    16201 tttttatcta atatagtttg accgaaagca tgatctaaaa ctattttatc aggcgcatgc
    16261 tctttagaag tattttcttc atttttaaca gaattagaag aacaagcgct aaaaactata
    16321 cacatagcta aaatagctat tagaaaaaat ttgtttttca taaaaactcc ttaaacatat
    16381 ttcaagtcta ttgtatcgat aataattatc attgtcaata gatacagtta caaatttaat
    16441 aatataattt tttcaaaaaa gg
//
LOCUS       DAVBCA010000050        16132 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.050, whole genome shotgun sequence.
ACCESSION   DAVBCA010000050 DAVBCA010000000
VERSION     DAVBCA010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16132)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16132)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16132
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.050"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            145..6831
                     /locus_tag="VQU19_001588"
     CDS             145..6831
                     /locus_tag="VQU19_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HET2480815.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTVEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQTSNQEKPLKEDAKAVTNEEVNQMIEDRKVDFNQNWYF
                     KLNANSKEAIKPDVDVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGFKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKTVLGTEVARVRTLIGKEPKMPKTVGFVYSDGSREKLPVTWSQ
                     VDVSQAGVVTVKGTANGREVEAHVEVLAIAKELPTVKRIAPNTDLNSVDKSVSYVLTD
                     GSVQEYEVDSWEITEVDKAKLSVAGSRIQMTGQLAGETIHATLVVEEGNAAAPVVPTV
                     TVGGEAVTGLTSRQPMQYRTLSYGAQLPEVTASAENADVTVLQASAANGMRASIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLKAEYEGAKGQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQKPTLPTTVTVEYDKGFPKAHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRIEQYA
                     KEGVFTVNGRLEDTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRTNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAVRIRMVKADNKRGTSITEVQIFAKQVAAAKQGQIRIQVDGKDLANFNPD
                     LTDYYLESVDGKVPAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKDLTVEWEEVPAEN
                     LTKAGQFTVRGHVLGSDLVAEVTVRVTDKLGEALSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQAKLRFFA
                     DSGTDAPTKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IQLTKEKPVSAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKTGKERIFT
                     AINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSEASQTN
                     KAQLPNTGSAASQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(7079..7935)
                     /locus_tag="VQU19_001589"
                     /pseudo
     CDS             complement(7079..7935)
                     /locus_tag="VQU19_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270419.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(8146..8505)
                     /locus_tag="VQU19_001590"
     CDS             complement(8146..8505)
                     /locus_tag="VQU19_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HET2480816.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSILAIILVFFFLLKKRSFYYPKFIKFFWRAGFL
                     LTLIMYIEMIVELFLMK"
     gene            8597..9553
                     /locus_tag="VQU19_001591"
                     /pseudo
     CDS             8597..9553
                     /locus_tag="VQU19_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            9537..10094
                     /locus_tag="VQU19_001592"
     CDS             9537..10094
                     /locus_tag="VQU19_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET2480817.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQADLTNAQLILQGHETLDQFVIKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            10087..10341
                     /locus_tag="VQU19_001593"
     CDS             10087..10341
                     /locus_tag="VQU19_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480818.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERSVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            10353..12407
                     /locus_tag="VQU19_001594"
     CDS             10353..12407
                     /locus_tag="VQU19_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HET2480819.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKDKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            12586..13446
                     /locus_tag="VQU19_001595"
     CDS             12586..13446
                     /locus_tag="VQU19_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HET2480820.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLCFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNLSNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            13657..14367
                     /gene="ccdA2"
                     /locus_tag="VQU19_001596"
     CDS             13657..14367
                     /gene="ccdA2"
                     /locus_tag="VQU19_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HET2480821.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            14387..14953
                     /locus_tag="VQU19_001597"
     CDS             14387..14953
                     /locus_tag="VQU19_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HET2480822.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            14964..16076
                     /gene="msrB"
                     /locus_tag="VQU19_001598"
     CDS             14964..16076
                     /gene="msrB"
                     /locus_tag="VQU19_001598"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HET2480823.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
BASE COUNT         4901 a         3052 c         3565 g         4614 t
ORIGIN      
        1 catatctacg gcaaggcgac actgacgaag tttgaattgg attttcgcag agtgtaaatt
       61 gttgaaacta ggttgtcata ccatgtatac cacttgggct ttggtagtag ctaactgcac
      121 taaatataat ataaggaggg ttttatgggg aaaggccatt ggaatcggaa aagagtttat
      181 agcattcgta agtttgctgt gggagcttgc tcagtaatga ttgggacttg tgcagttcta
      241 ttaggaggaa atatagctgg agaatctgta gtttatgcgg atgaaacact tattactcat
      301 actgttgaga aacctaaaga ggaaaaaatg atagtagaag aaaaggctga taaagctttg
      361 gaaactaaaa atgtagttga aaggacagaa caaagtgaac ctagttcaac tgaggctatt
      421 gcatctgaga agaaagaaga tgaagccgta actccaaaag aggaaaaagt gtctgctaaa
      481 ccggaagaaa aagctccaag gatagaatca caaacttcaa atcaagaaaa accgctcaag
      541 gaagatgcta aagctgtaac aaatgaagaa gtgaatcaaa tgattgaaga caggaaagtg
      601 gattttaatc aaaattggta ttttaaactc aatgcaaatt ctaaggaagc cattaaacct
      661 gatgtagacg tatctacgtg gaaaaaatta gatttaccgt atgactggag tatctttaac
      721 gatttcgatc atgaatctcc tgcacaaaat gaaggtggac agctcaacgg tggggaagct
      781 tggtatcgca agactttcaa actagatgaa aaagacctca agaaaaatgt tcgccttact
      841 tttgatggcg tctacatgga ttctcaagtt tatgtcaatg gtcagttagt ggggcattat
      901 ccaaatggtt ataaccagtt ctcatatgat atcaccaaat accttcacaa agatggtcgt
      961 gagaatgtga ttgctgtcca tgcagtcaac aaacagccaa gtagccgttg gtattcagga
     1021 agtggtatct atcgtgatgt gactttacaa gtgacagata aggtgcatgt tgagaaaaat
     1081 gggacaacta ttttaacacc aaaacttgaa gaacaacaac atggcaaggt tgaaactcat
     1141 gtgaccagca aaatcgtcaa tacggacgac aaagaccatg aacttgtagc cgaatatcaa
     1201 atcgttgaac gaggtggtca tgctgtaaca ggcttagttc gtacagcgag tcgtacctta
     1261 aaagcacatg aatcaacaag cctagatgcg attttagaag ttgaaagacc aaaactctgg
     1321 accgttttaa atgacaaacc tgccttgtac gaattgatta cgcgtgttta ccgtgacggt
     1381 caattggttg atgctaagaa ggatttgttt ggttaccgtt actatcactg gactccaaat
     1441 gaaggtttct ctttgaatgg tgaacgtatt aaattccatg gagtatcctt gcaccacgac
     1501 catggggcgc ttggagcaga agaaaactat aaagcagaat atcgccgtct caaacaaatg
     1561 aaggagatgg gagttaactc catccgtaca acccacaacc ctgctagtga gcaaaccttg
     1621 caaatcgcag cagaactagg tttactcgtt caggaagagg cctttgatac ttggtatggt
     1681 ggcaagaaac cttatgacta tggacgtttc tttgaaaaag atgccactca cccagaagct
     1741 cgaaaaggtg aaaaatggtc tgattttgac ctacgtacca tggtcgaaag aggcaaaaac
     1801 aaccctgcta tcttcatgtg gtcaattggt aatgaaatag gtgaagctaa tggtgatgcc
     1861 cactctttag caactgttaa acgtttggtc aaggttatca aggatgttga taagactcgc
     1921 tatgttacca tgggagcaga taaattccgt ttcggtaatg gtagcggagg gcatgagaaa
     1981 attgctgatg aactcgatgc tgttggattt aactattctg aagataatta caaagccctt
     2041 agagctaagc atccaaaatg gttgatttac ggttcagaaa catcttcagc tacccgtaca
     2101 cgtggaagtt actatcgccc tgaacgtgaa ttgaaacata gcaatggacc tgagcgtaat
     2161 tatgaacagt ctgactatgg aaatgatcgt gtgggttggg ggaaaacagc aaccgcttca
     2221 tggacttttg accgtgacaa cgctggctat gctggacagt ttatctggac aggtacggac
     2281 tatattggtg aacctacacc atggcacaac caaaatcaaa ctcctgttaa gagctcttac
     2341 tttggtatcg tagatacagc cggcattcca aaacatgact tctatctcta ccaaagccaa
     2401 tgggtttctg ttaagaagaa accgatggta caccttcttc ctcactggaa ctgggaaaac
     2461 aaagaattag catccaaagt agctgactca gaaggtaaga ttccagttcg tgcttattcg
     2521 aatgcttcta gtgtagaatt attcttgaat ggaaaatctc ttggttttaa gactttcaat
     2581 aaaaaacaaa ccagcgatgg gcggacttac caagaaggtg caaatgctaa tgaactttat
     2641 cttgaatgga aagttgccta tcaaccgggt accttggaag caattgctcg tgatgaatct
     2701 ggcaaggaaa ttgctcgaga taagattacg actgctggta agccagcggc agttcgtctt
     2761 attaaggaag accatgcgat tgcagcagat ggaaaagact tgacttacat ctactatgaa
     2821 attgttgaca gccaggggaa tgtggttcca actgctaata atctggttcg cttccaattg
     2881 catggccaag gtcaactggt cggtgtagat aacggagaac aagccagccg tgaacgctat
     2941 aaggcgcaag cagatggttc ttggattcgt aaagcattta atggtaaagg tgttgccatt
     3001 gtcaaatcaa ctgaacaagc agggaaattc accctgactg cccactctga tctcttgaaa
     3061 tcgaaccaag tcactgtctt tactggtaaa aaagaaggac aagagaagac tgttttgggg
     3121 acagaagtag caagagttcg tacattaatt ggtaaagaac caaaaatgcc gaaaacagta
     3181 ggttttgtat acagcgatgg tagtcgtgaa aaacttccag taacttggtc tcaagtcgat
     3241 gttagtcaag caggagttgt gactgttaaa ggtacagcaa atggacgtga ggtagaggct
     3301 catgtcgagg ttctagcaat tgcgaaagaa ttaccaacag ttaaacgtat tgctccaaat
     3361 actgacttga attctgtaga caaatctgtt tcttatgttt tgactgatgg aagtgtacaa
     3421 gagtacgaag tagatagctg ggagattacg gaagtagata aagccaaact ttcagtagct
     3481 ggatcacgta ttcaaatgac tggtcagtta gctggagaaa ctattcatgc aacccttgtg
     3541 gtagaagaag gaaatgctgc agcacctgta gtgccaactg ttactgttgg aggtgaggca
     3601 gtaacaggtc ttactagtcg acaaccaatg caatatcgta ctctatctta tggtgcccaa
     3661 ctgccagaag tcacagcaag tgctgaaaat gctgatgtga cagttcttca agcaagcgca
     3721 gcaaacggca tgcgtgcgag catctttatt cagcctaaag atggtggtcc tcttcaaacc
     3781 tatgcaattc aattcctaga agaagcacca aaaattgctc acttgagttt gcaagtggaa
     3841 aaagctgaca gtctcaaaga agaccaaact gtcaaattgt cggttcgagc tcactatcaa
     3901 gatggaacgc aagctgtatt accagctgac aaagtaacct tctctacaag tggtgaaggg
     3961 gaagtcgcaa ttcgtaaagg aatgcttgag ttgcataagc caggagcagt cactctcaaa
     4021 gcggaatatg agggagctaa aggccaagtt gaactcacta tccaagccaa tactgagaag
     4081 aagattgcgc aatctatccg tcctgtaaat gtagtcacag atttgcatca aaaacctact
     4141 cttccaacaa cagtaacggt tgagtatgac aaaggtttcc ctaaagctca caaagtcact
     4201 tggcaagcta ttccgaaaga aaaactagac tcctatcaaa catttgaagt actaggtaaa
     4261 gttgaaggaa ttgaccttga agcgcgtgca aaagtctctg tagaaggtat cgtttcagtt
     4321 gaagaagtca gtgtgacaac tccaatcgca gaagcaccac aattaccaga aagcgttcgg
     4381 acatatgatt caaatggtca cgtttcatca gctaaggttg catgggatgc gattcgtata
     4441 gagcaatacg ctaaggaagg tgtctttaca gttaatggtc gcttagaaga tactcaatta
     4501 acaactaaac ttcatgttcg cgtatctgct caaactgagc aaggtgcaaa catttctgac
     4561 caatggaccg gttcagaatt gccacttgcc tttgcttcag attcaaatcc aagcgaccca
     4621 gtttcaaatg ttaatgacaa gctcatttcc tacaataacc aaccagccaa tcgttggaca
     4681 aactggaatc gtactaatcc agaagcttca gtcggtgttc tgtttggaga ttcaggtatc
     4741 ttgagcaaac gctccgttga taatctaagt gtcggattcc acgaagacca tggagttggt
     4801 gcaccgaagt cttatgtgat tgagtattat gttggtaaga ctgtcccaac agctcctaaa
     4861 aaccctagtt ttgttggtaa tgaggaccat gtctttaatg attctgccaa ctggaaacca
     4921 gttactaatc taaaagcccc tgctcaactc aaggctggag aaatgaacca ctttagcttt
     4981 gataaagttg aaacctatgc tgttcgtatt cgcatggtta aagcagataa caagcgtgga
     5041 acgtctatca cagaggtaca aatctttgcg aaacaagttg cggcagccaa acaaggacaa
     5101 ataagaatcc aagttgacgg caaagactta gcaaacttca accctgattt gacagactac
     5161 taccttgagt ctgtagatgg aaaagttccg gcagtcacag caagtgttag caacaatggt
     5221 ctcgctaccg tcgttccaag cgttcgtgaa ggtgagccag ttcgtgtcat cgcgaaagct
     5281 gaaaatggcg acatcttagg agaataccgt ctgcacttca ctaaggataa gaacttactt
     5341 tctcataaac cagttgctgc ggttaaacaa gctcgcttgc tacaagtagg tcaagcactt
     5401 gaattgccga ctaaggttcc agtttacttc acaggtaaag acggctacga aacaaaagac
     5461 ctgacagttg aatgggaaga agttccagca gaaaatctga caaaagcagg tcaatttacc
     5521 gttcgaggcc atgtccttgg tagtgatctt gttgctgagg tcactgtacg agtgacagac
     5581 aaactaggcg aagctctttc agataaccct aactatgatg aaaacagtaa ccaggccttt
     5641 gcttcagcaa ccaatgatat tgacaaaaac tctcatgacc gcgttgacta tctcaatgac
     5701 ggagatcatt cagaaaatcg tcgttggaca aactggtctc caacaccatc ttctaatcca
     5761 gaagtatcag cgggtgtgat cttccgtgaa aatggtaaga ttgtagaacg gactgttgcc
     5821 caagccaaac ttcgtttctt tgcagatagt ggtacggatg caccaactaa actcgtttta
     5881 gaacgctatg tcggtccaga gtttgaagtg ccaacctact attcaaacta ccaagcctac
     5941 gacgcagacc atccattcaa caatccagaa aattgggaag ctgtgcctta tcgtgcggat
     6001 aaagacatcg cagctggtga tgaaatcaac gtaacattta aagctgtcaa agccaaagct
     6061 atgagatggc gtatggagcg taaagctgac aagagcggtg ttgcgatgat tgagatgacc
     6121 ttccttgcac cgagtgaatt gcctcaagaa agtacgcaat cgaagattct tgtagatgga
     6181 aaagaacttg ctgatttcgc tgaaaatcgt caagactatc aaattaccta taaaggtcaa
     6241 cggccaaaag tctcagttga agaaaacaat caagtagctt caactgtggt agatagtgga
     6301 gaagatagcc ttccagtact tgttcgcctc gtttcagaaa gtggaaaaca agtcaaggaa
     6361 taccgtatcc agttgactaa ggaaaaacca gtttctgctg tacaagaaga tcttccaaaa
     6421 ctcgaatttg ttgaaaaaga tttggcctac aagacagttg agaaaaaaga ttcaacactg
     6481 tatctaggtg aaactcgtgt agaacaagaa ggaaaaactg gtaaagaacg tatctttaca
     6541 gcgattaatc ctgatggaag taaggaagaa aaactccgtg aagtggtaga agctccgaca
     6601 gaccgcatag tcttggttgg aaccaaacca gtagctcaag aagctaaaaa accacaagtg
     6661 tcagaaaaag cagatacaaa accaattgat tcaagtgaag ctagtcaaac taataaagcc
     6721 cagttaccaa atacaggtag tgcggcaagc caagcagcag tagcagcagg tttagctctt
     6781 ctaggtttga gtgcaggatt agtagttact aaaggtaaaa aagaagacta gaaattttga
     6841 taccttcttt atcattaaag accaaagaaa aactcttgtc ctaaatagaa gataaagagt
     6901 ctggaacaaa atagttctca accacaaaaa agctagatat ttccaattgc ggaactctag
     6961 ctttttaatt ttgagtcgtt ctcttattgt atagtagatt gaaactagaa tagtacactt
     7021 ctacttctaa aacattgtta gaaatcaatt tgactgtcct tatcgatttg tcctgttctt
     7081 atttcatttc actatgtttt aggaggttat tggccataag taccaatccc atgtcaattc
     7141 tcacttgacg cttccctctc agattacatc tcttgtaacc caaacaagcc tttatctgcc
     7201 caaagacagg ttccacatca atcttgcgtt gagcgaaaat ctgtctacct tggggagata
     7261 aaagcgcctg acattcttta gctttcaagt tttgatagcg ttcgttcata tacagtccct
     7321 tttgagggac tgattcaggt tcatcagcgt agtaaacctt gatttcctgt tgaaagtctg
     7381 tctgtgtttt ctggtacttg atatggtgaa aacgatagca ccagccatca ggatgtgtgt
     7441 agctatcctc cttgtcatta tagtgccaat tcgctaagtt tttagctgac tgtttatacc
     7501 ctctcttttg ttccttatca aacatggcat atttaatcag aaggggagtg atttcttctt
     7561 gaaaatagac ctgtatctgt tcttgaagtt tggcggagaa tttctctgtc gttttcttcc
     7621 acacaaaact atacttgttg gcattggctt caatcttagt tccgtcaata aacaaacaat
     7681 ctaaggtcac taactcttcc atttttcaat ttttcgacca gagaaaatcc cttgtgaata
     7741 ggcaaataga agagtagata caagcatttt agggtgataa gacgggcgat caaaggcatg
     7801 atagaaggcg tggaagtgac aatcctccaa ggtattcacc actttttcaa tagtaaaaac
     7861 gagatgatct tgtggcaaga aggaactgat ttctagtggt aaagttgttt gatttgtgtt
     7921 atagtgaata tgcatgggat agcctttcta aatggtttat taagcaattc tattttacca
     7981 agactatcgc aaccatgcaa aaaagcaacg gcaaatccgt tgcctttttt ggagataaga
     8041 gactattgtc ccagactctt ttctttgtat aaaattgtat agtgttattg tctatactat
     8101 tttgtagaga aagcaaaaat ccctagaaaa tgcttaggga ttcgactatt tcattaagaa
     8161 caattcaaca atcatttcta tatacatgat aagggttaat aagaatcctg cacgccagaa
     8221 gaatttgata aatttaggat agtaaaagct gcgttttttc aaaaggaaga aaaagacgag
     8281 aataatggct aggatcgaga gggctagccc cagtctaggg aggaaattat gggtaaaggt
     8341 tttagctgta atcaagtaat actcaaatac caagactgga aaagccaaat ccgcaaagtt
     8401 tcgtcctagt ttttttaatc taaaaagttt ggttaggata atgcagacga ctaaggtcag
     8461 tatcaataat aaaatagatg ctaatttcat taaaatcata cccatattgt atcataaaaa
     8521 aaggctaatg gaaacgagaa acagaggaat ttataggaaa gtcaggcttt tgagattgtg
     8581 ggtgattttt gttataatga aagttataaa atcttataat accttgaatg attattatcg
     8641 aaaactcttt ggagaaaaga cttttaaagt ccctattgat gcgggatttg actgtcccaa
     8701 tcgtgatgga actgtggctc atggaggctg tactttttgt acggtttccg gttctggaga
     8761 tgccattgtg gcaccagatg cgcctatccg tgagcaattt tataaggaaa ttgactttat
     8821 tcatcgtaag tggccagatg ttcagaagta tctggtttat tttcaaaatt ttaccaacac
     8881 ccatgaaaag gtggaagtta ttcgagagcg ttatgaacag gctatcaatg agccaggtgt
     8941 ggtaggaatc aatattggaa cgcgcccaga ctgtttacca gacgaaacca tcgaatattt
     9001 ggctgagtta tcggagtgca tgcatgtgac ggttgaattg ggcttgcaaa ctacttatga
     9061 agcaacctct gacctgatta accgtgcgca ttcttatgaa ttgtaggtgg aaacggtcaa
     9121 gcgtttgaga aagtatccaa aaattgagat tgtttcccat ttgatcaatg gtttgcctgg
     9181 tgaaacccat gagatgatgg ttgaaaatgt ccgccgttgt gtcacggata acgatattca
     9241 agggattaaa ctgcatttgc tccatcttat gacaaatact cgtatgcaac gagattacca
     9301 tgaggggcgt ttacaattga tgagtcagga cgaatatgtc agggtcatct gtgaccaact
     9361 ggaaattatt cccaaacata tcgtcatcca tcgaattaca ggagatgcgc ctagggatat
     9421 gctgcttggg cctatgtgga gcctcaataa atgggaagct ctcaacagca ttgagatgga
     9481 gatgcgacgt cgtggaagtg ttcaaggatg caaggctgta aaacaggagt ttgaaaatga
     9541 aaagaccact tgagatggca catgattttt tggctgaggt cgtgacaaaa gaggatgtcg
     9601 tagtggatgc gactatggga aatggtcatg acacgctttt tttagccaag ctagccaagc
     9661 aagtctatgc ctttgatatt cagaagcaag ccttggaaaa gacccaagag cgtttgcatc
     9721 aggctgactt gacaaatgcc cagttaatct tgcaaggcca tgagacactg gaccagtttg
     9781 tgataaaagc taaggcaggg atttttaatc tgggctattt gccgtcagct gataagtctg
     9841 tcatcacccg accgcagaca acgattgagg cattagaaaa gctatgtggc ttacttgtca
     9901 aaggtggacg aattgctatt atgatttact atggtcatga aggaggcgat ctcgagagag
     9961 atgctgtctt ggattttgtg atccagttga accaacaaga gtacacagct gccatttacc
    10021 gaactttaaa ccaagtcaac aacccgccgt ttttagtgat gattgaaaaa ttagagagat
    10081 acagacatgg ataaacaata cctacacgaa aagctggatg ccatgcgcca gaattttgtt
    10141 gaatcaaccc accacgaacg atcggtgggc gtgctagacc aagcgcatat gagcaaaaaa
    10201 atgcttaaaa tcaagaaaaa attagttgct cttgaaatgg aacggtgcca gagaaaaatt
    10261 gagcacaaag actgttccaa gattgaccaa aaaatcaaag agcagaagga gatatttgaa
    10321 tcctgttgta aaaaagatta aggaggacgt gcgtggaatt actgatttac ctcatcctat
    10381 ttttactggt tttgattgtc tcaagtacaa ccaataagct cctgcccttt ttgcctctcc
    10441 ctttggtgca gattcttttg ggaattgtga ttggtctctt tttacccaat actgactttc
    10501 accttaatac ggagttgttt ttggcactgg ttatcggacc cttgcttttc cgagaggctg
    10561 aagaagcaga tgttacggct attttaaaac actggcgaat cattgtttat ctcatatttc
    10621 cagtgatttt tatctcgacc ttgagtttgg gtggcttggc ccatcttctt tggttcagcc
    10681 ttcccttggc agcttgcttg gctgttgggg cagcccttgg tcctacggac ttggtggcct
    10741 ttgcctctct ttcggagcgt tttagctttc ctaagcgcgt gtccaatatt cttaagggcg
    10801 aaggactctt gaatgatgct tctggtttgg tggcttttca ggtagctttg acagcttgga
    10861 caactggagc tttttctctg gggcaagcta gcagttcgct catcttttca atcctaggcg
    10921 gttttttaat tggattttta acggccatga ccaaccgctt cctccatacc ttcttgctaa
    10981 gtgtgcgcgc aacggatatt gccagtgaac ttttattaga attgagtttg cctctagtga
    11041 ccttctttct ggcagaagaa gttcatgttt caggtattat tgccgtcgta gttgctggaa
    11101 ttttaaaggc aagtcgcttc aagaaaatca cgctcctcga agcccaagtg gatacggtga
    11161 ccgagacggt ctggcataca gtgaccttta tgctcaacgg ttctgtcttt gtgattttag
    11221 ggatggagtt ggaaatgata gcagaaccta tcttgaccaa tccaatctat aatcctctac
    11281 ttttattgct atctctcatc gcccttacct ttgtcctctt tgtcattcgt tttattatga
    11341 tctatggcta ttatgcctat agaacccgac gcctcaagaa aaagctaaat aagtatatga
    11401 aggacatgtt tctcttgacc ttttcaggtg ttaagggaac ggtgtcgatt gctacgattc
    11461 tcttgatacc aagtaatcta gaacaggagt atcctctttt gcttttcctt gttgcaggtg
    11521 tgacgcttgt cagcttttta acaggtctct tggtcttgcc tcatctttct gatgaagagg
    11581 aagaaagcaa ggattatctc atgcatatcg ccattttgaa tgaagtaacg ctagagttgg
    11641 aaaaagagtt ggaagacacc agaaataaac ttcccctcta tgcggctatt gacaattatc
    11701 atggacgtat tgaaaatctc attttaagcc aagaaaacca ggatgatcaa gaagattggg
    11761 ctgctttgaa actcttgatt cttagtattg aaagtgatgg tttggaacag gcctatgaag
    11821 aggggaacat tagcaatcgt gcttaccgag tttaccaacg ttatctgaaa aatatagaac
    11881 aaggaatcaa tcgtaaactt gcctcaagac tgacctatta ttttcttgtt tccttgagga
    11941 ttttacgttt tctccttcat gaagttttta ctcttggaaa gaccttccgt agctggaagg
    12001 acaaggagca aagccgtctc cgtgctcttg attatgacca aattgcagag ctctatcttg
    12061 ccaatacaga gatgattatt gaaagtttgg aaaacctgaa gggagtctac agacgctctt
    12121 tgattagttt tatgcaggag tctcgtcttc gagaaacagc tattatcagc agtggtgcct
    12181 ttgtcgaacg ggttatcaat cgtgtcaaac ccaacaatat cgatgaaatg ctgagaggct
    12241 attatctgga gcgcaagttg attttcgaat acgaagaaaa acgattgatt acgactaagt
    12301 atgccaagaa attacgacaa aatgtaaata acttagagaa ctattccttg aaggaagctg
    12361 ccaataccct gccgtatgat atggtggaat tggtaagaag aaattagtta atactcttcg
    12421 aaaatctctt caaaccacgt cagcgtcgcc ttggattata tatgtgactg acttcgtcag
    12481 tttcatctac aacctcaaag cagggctttg agcaacctgc ggctagcttc ctagtttgct
    12541 ctttgatttt cattgagtat aagattataa atgaaggagt atgacatgaa aaagtggtgg
    12601 aaagagctga tagacaagcc tttattaaaa gcttttttgc attattatca agcatcagat
    12661 agtgagttga ccagtgtcgc agtagcctac tattggttga tttcgatttt ccccctgctt
    12721 ttggtggtgg tcaatatcct cccctatttt cagattcctg tgggagaatt tctgtgcttt
    12781 atgaaagacg ttctgccccc aagcctctat gaaggtgtgg aaaaaatagc cagagaagtt
    12841 ttgacgcaac cttcaacagg tttattgagt ttttctgttt tatcggcgtt atggagtttt
    12901 tcaaaatcta tgaatttctt gcaaaaagct tttaacaagg cttatggcgt cgaaaagagt
    12961 cgtggactta tttcccatca gatgctaagt ctcctagtca gttttggctt gcagctcctc
    13021 tttgcgtttg ccttgttttt gatcttattt ggtcagatga ttttggcttt acttgctcat
    13081 tattggacaa aagatggcat tatctatcag gctttacaag ggttggcagg tcctctgatt
    13141 tacgccctcc tctttgctat cttggtcatg ctttattatt ttcttcccaa tctatctaac
    13201 aggaaaatta gctataccct accaggcagt gcctttgttc tcttagtgat tttaggttta
    13261 ctaactctgt tctctagtta tctcaattac tatgtccatc atttggtgga tgtccgaatt
    13321 ttaggttccg ttcttcttgt tgttatgatg ttttggttta tcttgattgc taaaattgtt
    13381 atcctaggcg cggttatcaa tgccagtatg cagagtttga aagatccggt ctttaaaaaa
    13441 gactaactat ttatccatta caaaagcgca tagtatcaaa actttataga accttgatac
    13501 tatgcgcttt tgtgctttga cagttttttg tatagttttt gtccaagatt tctaaatcat
    13561 ctgattaaat tcctattttc ccctatcatt gtccctgttt tttcgaaaat ggaaggagta
    13621 taataaatct atcaataaaa tgataggagg aactttatgg gtcatatttt cttttttcta
    13681 agtgtctttt tggcagggat tctatccttc ttttctcctt gtatcttacc tttgttaccg
    13741 gtctatacag gagtgttact agatgataag gatggtgctc aggcttctag cggcaaattt
    13801 tcaatctcag ttactagttt attacgaact ctggccttta tagcaggaat ttcctttata
    13861 tttattttgt tgggctatgg agctggtttt ttaggcgatt tgctttatgc ttcttggttc
    13921 caatatctta ctggggcaat tattatcctt cttggtttgc accaaatgga gattctacac
    13981 tttaaggggc tttataagga aaagaggcta caactgcaag gacaggggca aaatggtaag
    14041 ggctatagtc aggcattttt attgggcttg acctttagtt ttgcttggac gccttgcgtg
    14101 gggccggttc tggggtctgt tttggccttg gcggcttcag gtggttcagg agcttggcag
    14161 ggagctggtc tcatgttggt gtatacgctg ggcttggcgc taccattctt gcttctagct
    14221 ctgacctcta gttatgtttt gaaacatttc cgaaaacttc atccctatct cggaatcctc
    14281 aaaaaagtgg gtggttttct cattattgtg atgggactct tggttctgtt tggaaatgct
    14341 tcaattttaa gtcaattatt tgaataaaat ggaaaggaat atcaatatga aaaaatggca
    14401 aacatgtgtt cttggagcag gttcgctcct ttgtttgacg gcttgttcag gcaagtccgt
    14461 gactagtgaa caccaaacga aagatgaaat gaagacggag cagacagcta gtaaaacaag
    14521 cgcagctaaa gggaaagagg tggctgattt tgaattgatg ggagtagatg gcaagaccta
    14581 ccgtttatct gattacaagg gcaagaaagt ctatctcaaa ttctgggctt cttggtgttc
    14641 catctgtctg gctagtcttc cagatacgga tgagattgct aaagaagctg gtgatgacta
    14701 tgtggtcttg acagtagtgt caccaggaca taagggagag caatctgaag cggactttaa
    14761 gaattggtat aagggattgg attataaaaa tctcccagtc ctagttgacc catcaggcaa
    14821 acttttggaa acttatggtg tccgttctta cccaacccaa gcctttatag acaaagaagg
    14881 caagctggtc aaaacacatc caggattcat ggaaaaagat gcaattttgc aaactttgaa
    14941 ggaattagcc taggaggtgt cttatgaatg ataagttaaa aatcttcttg ttgctaggag
    15001 tattttttct agccataacc ggtttctatg ttctattgat acgaaatgca gggcagacag
    15061 atgcctcgca aattgaaaag gcggcagtta gccaaggagg aaaagcagtg aaaaaaacag
    15121 aaattagtaa agacgcagac ttgcacgaaa tttatctagc tggaggttgt ttctggggag
    15181 tggaggaata tttctcacgc gttcccgggg tgacggatgc cgtttcaggc tatgcaaatg
    15241 gtagaggaga aacaaccaag tacgaattga ttaaccaaac aggtcatgca gaaaccgtcc
    15301 atgtcaccta tgatgccaag caaatttctc tcaaggaaat cctgcttcac tatttccgca
    15361 ttatcaatcc aaccagcaaa aataaacaag gaaatgatgt ggggacccag taccgtactg
    15421 gtgtttatta cacagatgac aaggatttgg aagtgattaa ccaagtcttt gatgaggtgg
    15481 ctaagaaata cgatcaacct ctagcagttg aaaaggaaaa cttgaagaat tttgtggtgg
    15541 ctgaggatta ccatcaagac tatctcaaga aaaatccaaa tggctactgc catatcaatg
    15601 ttaatcaggc ggcctatcct gtcattgatg ccagcaaata tccaaaacca agtgatgagg
    15661 aattgaaaaa gaccctgtca cctgaggagt atgcagttac ccaggaaaat caaacagaac
    15721 gagctttctc aaaccgttac tgggataaat ttgaatccgg tatctatgtg gatatagcaa
    15781 ctggggaacc tctcttttca tcaaaagaca aatttgagtc tggttgtggc tggcctagtt
    15841 ttacccaacc catcagtcca gatgttgtca cctacaagga agataagtcc tacaatatga
    15901 cgcgtatgga agtgcggagc cgagtaggag attctcacct tgggcatgtc tttacggatg
    15961 gtccacagga caagggcggc ttacgttact gtatcaatag cctctctatc cgctttattc
    16021 ccaaagacca aatggaagaa aaaggctacg cttatttact agattatgtt gattaatact
    16081 cttcgaaaat ctcttcaaac cacgtcagcg tcgccttacc gtatgtaggg tt
//
LOCUS       DAVBCA010000051        15005 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.051, whole genome shotgun sequence.
ACCESSION   DAVBCA010000051 DAVBCA010000000
VERSION     DAVBCA010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15005)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15005)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15005
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.051"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            150..488
                     /locus_tag="VQU19_001599"
     CDS             150..488
                     /locus_tag="VQU19_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000176371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HET2480824.1"
                     /translation="MTLTIHVYYKGDGDCAIKFAREMLESGLVAEIRCQKGNLKYEYF
                     LPIEKEGIILLIDQWINQEALDEHHQSNTMQKILDLRKKYHLQMQVERYIEDDSGMPE
                     SDKSFIDTGN"
     gene            678..2114
                     /locus_tag="VQU19_001600"
     CDS             678..2114
                     /locus_tag="VQU19_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HET2480825.1"
                     /translation="MTTFKDGFLWGGAVAAHQLEGGWQEGGKGISVADVMTAGRHGVA
                     REITLGVLEGKYYPNHEAIDFYHRYKEDIALFAEMGFKCFRTSIAWTRIFPKGDELEP
                     NEEGLQFYDNLFDECLKNGIEPVITLSHFEMPYHLVTEYGGWKNRKLIDFFARFAEVV
                     FKRYKDKVKYWMTFNEINNQANYQEDFAPFTNSGIVYEEGDNREAIMYQAAHYELVAS
                     ARAVKIGHEINPDFQIGCMIAMCPIYPVTCNPKDILMAMKAMQKRYYFADVHVLGKYP
                     EHIFKYWERKGISVDFTDQDKEDLLGGTVDYIGFSYYMSFAIDSHRENNPYFDYLETE
                     DLVKNNYVKASEWEWQIDPEGLRYALNWFTDHYHLPLFIVENGFGAIDQVAADGMVHD
                     DYRIEYLGAHIREMKKAVVEDGVDLMGYTPWGCIDLVSAGTGEMRKRYGFIYVDKDDN
                     GKGSYNRSPKKSFGWYKKVILSNGESVE"
     gene            2166..2405
                     /locus_tag="VQU19_001601"
     CDS             2166..2405
                     /locus_tag="VQU19_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SemiSWEET family sugar transporter"
                     /protein_id="HET2480826.1"
                     /translation="MIGSIAAILTTFAFLPQVFRVVKTKDTGSIALGMYVMQVIGIAL
                     WLAHGIRIGDLPLILANSVSFLLSGIILFYKLKYK"
     gene            2535..2849
                     /locus_tag="VQU19_001602"
     CDS             2535..2849
                     /locus_tag="VQU19_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HET2480827.1"
                     /translation="MAKALIICAAGMSSSLMAQKTTEFLKGKGKDIVVDAISATEGGK
                     AIAAAAFDLYLVSPQTKMYFKQFEEAGSKAGKPVVQIPPQAYIPIPMGIEKMANLILE
                     NI"
     gene            2967..4946
                     /locus_tag="VQU19_001603"
     CDS             2967..4946
                     /locus_tag="VQU19_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HET2480828.1"
                     /translation="MNVLNIKEKDILQFLIKNKERFVTSKELAEYLSCSDRTVRNVLK
                     LIEKTMIIQGVRLISKQGQGYQIFFENQGAYQEFRQTYELEEDYTKTAVSKGDDRLVF
                     ILNKLLFEQVPVLFDDLADELYVSRSTLSHDFRKIRVMLSEYNLSIESRANKGVYVSG
                     EERDKRRFIINYFLENQFFKTIHCYVKFNFFAQTVPLEEFARIVLDECQEANLKLSDF
                     VLQNLVVHIALSVIRLKSGFEIKNIDCQMTDDAIERKVAQRILSKVREVTNQEFPVQE
                     IDYITLHLLAKSQQCQKNQKNISEEVLKKSLFKTFQNLGLDDMYNFSSDFQLIEGLIT
                     HLMTLQVRLESRITLNNPLVDEIKQNYSDIFFMTREILANMDKFLEWTISDDEVAYVS
                     LHFLAAMERSKESTKFNILAICATGFGAAQMLRNRLETEFGKRVEVVDVIGYYELNQE
                     KLKGIDFIVSAVDLSNLYFQIPVFKVSVFLKSDEMEMIRKAMDQMQVSSYVQSSKINK
                     FENNSFRQYFSKENFLICTESDKVNLLEKMVESLSVGESNEFEQSLLYGIKQREELSS
                     VVFSEKIAVPHPIQPFGTEGKVSVAICKDSLLWDNQSSYVQLVFLLSPSIYGNEGLAT
                     VTKKIVSLTENDELQNQLISCNNFEDFISIFEKIK"
     gene            4956..5270
                     /locus_tag="VQU19_001604"
     CDS             4956..5270
                     /locus_tag="VQU19_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HET2480829.1"
                     /translation="MNQEELQVAAFEIILHSGNARSEIHEAFAKMREGSFDDAESKLN
                     QSNEIILEAHHAQTKLLQEYASGVEIKIEIIMVHAQDHLMTTMTLLEVAKEMLALYKK
                     VN"
     gene            5301..5807
                     /locus_tag="VQU19_001605"
     CDS             5301..5807
                     /locus_tag="VQU19_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480830.1"
                     /translation="MDKKERQKIEQQRREMALTNTFFNRYLLLRYSIALFFFGNIYWL
                     LNQFINPSPIIIFPIMLIVFSILATVEQFKLYGNRKEKLGITLMFVRIQILISIGLLV
                     LTWTSWFKNLFPIFENNQVARLFVFVVLLLGLVLSLLDIRRIKKIYKRTDKAYQQFVQ
                     LEKNSLSL"
     gene            5887..7233
                     /gene="celB"
                     /locus_tag="VQU19_001606"
     CDS             5887..7233
                     /gene="celB"
                     /locus_tag="VQU19_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HET2480831.1"
                     /translation="MDQQNGLFGFLENHVMGPMGKLAQFKVVRAITAAGMAAVPFTIV
                     GSMFLVFSILPQAFSFWPIVADIFSASFDKFTSLYMVANYATMGSLSLYFVLSLAYEL
                     TKIYAEEEELNMNPLNGALLALMAFVMTVPQIIFDGGMMKTVTSLKEGAVIADGWAMG
                     NGVARFGTTGIFTAIIMAIVTVLIYRMCVKHNWVIKMPEAVPEGVSRGFTALVPGFVV
                     AFVVIFINGLLVAMGTDIFKVIAIPFGFVSNLTNSWIGLMIIYLLTQLLWIVGIHGAN
                     IVFAFVSPIALANMAENAAGGHFAVAGEFSNMFVIAGGSGATLGLCLYIAFASKSEQL
                     KAIGRASVVPALFNINEPLIFGLPIIYNPALAIPFILAPMVTATIYYVANSLNFIKPI
                     IAQVPWPTPVGIGAFLGTADLRAVLVALVCAFAAFLVYLPFIRVYDQKLVKEEQGI"
     gene            7613..7789
                     /locus_tag="VQU19_001607"
     CDS             7613..7789
                     /locus_tag="VQU19_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480832.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            8199..10412
                     /locus_tag="VQU19_001608"
     CDS             8199..10412
                     /locus_tag="VQU19_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-xylosidase"
                     /protein_id="HET2480833.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSQTGSFEDRTTQLIYNRDFGQ
                     VSLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHFFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(10634..11110)
                     /locus_tag="VQU19_001609"
     CDS             complement(10634..11110)
                     /locus_tag="VQU19_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HET2480834.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDQKSGPLGKRIEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            11333..14533
                     /locus_tag="VQU19_001610"
     CDS             11333..14533
                     /locus_tag="VQU19_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HET2480835.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSPWTGSKAQGWSAWVDQKNSADASTRVIEAKDGA
                     ITISSHEKLRAAVHRMVPIEAKKKYKLRFKIKTDHKVGIAKVRIIEESDKDKRLWNSA
                     TTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVADQPSEDYQTD
                     KQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKEGTTNVIVSKDGKEV
                     KKIPLKILASVKDAYTDRLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSIS
                     SQADRTYLWEKFSNYKMSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSMEW
                     MHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDPE
                     HFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGFY
                     QDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAPL
                     LVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQS
                     DSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGFG
                     LSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTET
                     DAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFLG
                     SNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDSK
                     KNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYML
                     IPNVGRATFNQMIKELERSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVLK
                     RGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKNH
                     SDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            14913..15005
                     /locus_tag="VQU19_001611"
                     /pseudo
     CDS             14913..15005
                     /locus_tag="VQU19_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005576373.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
BASE COUNT         5003 a         2187 c         3082 g         4733 t
ORIGIN      
        1 atcgctataa gaaaaaatca ttttattggt ataaagaagt gattgaaagt aatggcgaaa
       61 cgttagataa ttagttcata aaaaacaagt ttagatcctc atctaaactt gtttttttaa
      121 aattgaagga tgattttgga ggatatgaga tgacattgac tattcatgta tattataaag
      181 gcgatggaga ttgtgcaata aagtttgcaa gagaaatgct tgaatctggg cttgtcgcag
      241 aaattagatg tcaaaaaggt aatttgaaat acgaatattt tttaccaatt gaaaaagagg
      301 gaattattct ccttattgat cagtggataa atcaagaagc tttagatgaa catcatcaat
      361 caaatacaat gcagaaaatc ttagatttaa gaaaaaaata tcacttgcag atgcaagttg
      421 aacgttatat agaagatgat tctgggatgc cagaaagcga taagtcgttt atagacacag
      481 ggaattagaa ttattgtgag agtttttgta gtttgaaagt attgaaaatc gtaaagatat
      541 cattacgaga atacaagaag atattgttct atttccatta aaaattactt ctttccttaa
      601 taataaggaa aaagaatacg ttttcatctt ttggtttgag gtttataata agaatatcaa
      661 agtcaggagg aaaaaagatg actactttta aagatggatt tttatggggt ggtgctgttg
      721 ctgctcatca acttgaaggc ggatggcaag aaggtggcaa aggaattagt gttgctgatg
      781 ttatgactgc tggtcgccat ggagtagctc gtgaaattac tttgggagtt ttagagggta
      841 aatattatcc aaatcatgag gcgatagatt tttatcatcg ttataaagaa gacatagcac
      901 tttttgctga aatgggattc aagtgcttcc gtacctctat tgcatggaca cgtatctttc
      961 caaaaggtga tgagttagag ccgaatgaag aaggattaca gttttatgat aatctttttg
     1021 atgaatgctt aaagaatggt attgaacctg tcatcactct atctcatttt gaaatgcctt
     1081 atcacttagt gaccgaatat ggtggttgga aaaataggaa attgattgat ttctttgctc
     1141 gttttgcaga agtcgtattt aaacgttaca aagataaggt taaatattgg atgactttca
     1201 atgaaatcaa taatcaagcg aattatcagg aagattttgc accatttact aactcaggta
     1261 ttgtatatga ggaaggtgat aatagagaag caattatgta tcaagcagca cattacgaat
     1321 tagttgcttc tgcacgagct gtaaaaattg gtcatgagat taatccagat tttcaaatag
     1381 gttgtatgat tgcgatgtgt ccaatttatc cagttacttg caatcctaag gatatcttaa
     1441 tggcaatgaa agctatgcag aagcgttatt attttgctga tgtgcatgtt ttaggtaaat
     1501 atcctgagca tattttcaag tattgggaac gaaaaggtat ttcagttgat tttactgacc
     1561 aggataaaga agatttactt ggtgggactg tagattacat tggtttcagt tactatatgt
     1621 cctttgctat agactctcat cgtgaaaata atccttattt tgattatctt gaaacagaag
     1681 atttagtgaa aaataattat gttaaggctt ctgaatggga gtggcaaatt gatccagaag
     1741 gtttacgtta tgcgttaaat tggtttacag accactatca cttaccactc tttattgttg
     1801 aaaatggttt tggagctata gatcaagttg cagcagatgg tatggtacat gatgattata
     1861 gaattgaata tctaggtgcc catattcgtg aaatgaaaaa ggctgtagtt gaagatggtg
     1921 ttgatttaat gggttatact ccatggggat gtattgattt ggtttcagct ggtaccggtg
     1981 aaatgcggaa acgttatggc tttatttatg tagataaaga tgacaatggg aagggaagtt
     2041 ataatcgttc cccgaaaaaa tcttttggct ggtataagaa agttatttta tctaacggtg
     2101 aatcagtaga atagtataaa caaactgaga ttattctcag tttgtttagc atattgagga
     2161 gacatatgat tggaagtatt gcagcaattt taacaacatt tgcattttta ccacaagttt
     2221 ttcgtgtagt taagacaaag gacacaggat ctattgctct aggtatgtat gttatgcaag
     2281 ttattggtat tgcattgtgg cttgctcatg gtattcgtat aggagacttg cctttgattt
     2341 tagcaaatag tgtttcattt ctactctcag gaataatttt attttataaa ttgaagtata
     2401 aataattttt ttccatatca tttaggaaaa tgagggaatt gtcattgaaa acgctttatt
     2461 ttataataaa aatagataac aaataagcca acttagcaca gctttgattg gatttaagaa
     2521 aaggagaaaa tattatggca aaagctttaa ttatttgtgc agcaggaatg tcttcatcac
     2581 ttatggcaca gaaaacaaca gagtttctaa aaggaaaagg gaaagatatt gtagttgatg
     2641 ctattagtgc tactgaagga gggaaagcta tcgcagcagc agcttttgat ttgtatcttg
     2701 tcagtcctca aacaaaaatg tactttaagc aatttgaaga ggctggttct aaagcaggaa
     2761 aaccagttgt acaaatacct cctcaagcct atattcctat tccaatggga attgaaaaaa
     2821 tggctaattt gattcttgag aatatttgat gaacacatga aatgtcaata aatatttaag
     2881 ttaagataaa ttgttttgag tttgatataa attgatttaa gtgtataata tgcttcaata
     2941 tatgaaaaca tacgttttag gagggaatga atgtgttaaa cattaaagag aaagatatcc
     3001 ttcaattttt aataaaaaat aaggaacgtt ttgttacaag caaagaactg gcagaatatt
     3061 tatcctgttc agatagaact gtccgtaatg tactgaaatt aattgagaag acaatgatta
     3121 ttcaaggagt ccggttgatt tcaaaacaag gtcaagggta tcaaatattt tttgagaatc
     3181 aaggcgctta ccaggagttt agacaaactt atgaactgga agaagactat acgaaaactg
     3241 cggtttcaaa aggtgatgat cgtttagtat ttatcttaaa taaattatta tttgagcaag
     3301 ttccagttct ttttgatgat ttagctgatg aactttacgt tagtcgttca acattatctc
     3361 atgatttcag aaagatacga gtgatgttat cagagtataa tttgtccatt gagagtaggg
     3421 cgaataaagg agtttatgtc tcaggcgagg aacgtgataa acgacgtttt atcataaatt
     3481 atttcctaga gaatcaattt tttaaaacaa tacattgcta tgtaaaattt aacttttttg
     3541 ctcaaactgt tccattagaa gaatttgcta gaattgtttt ggatgaatgc caagaggcca
     3601 acctaaaact atctgatttt gtactacaga atttagtagt tcacatagca ttgtctgtga
     3661 ttcgtttaaa atccggattt gaaataaaaa atatagactg tcagatgact gatgatgcaa
     3721 tagagagaaa ggttgctcaa agaattcttt ctaaagtaag agaagtaaca aatcaggaat
     3781 ttccagttca ggaaatagac tacattactt tgcatttgtt agctaagagt caacaatgtc
     3841 aaaaaaatca gaagaatatt tctgaagaag ttttaaaaaa atctttattt aaaacatttc
     3901 agaatttagg attagatgat atgtataact tttcttcaga tttccaacta attgaaggat
     3961 tgataactca tctaatgaca ctacaagtac gtttagaaag ccggattacc ttaaataacc
     4021 ctttggtaga tgaaattaaa cagaattata gtgatatatt ctttatgact agagaaattc
     4081 ttgcaaatat ggacaagttc ttggagtgga caatatcaga tgatgaagta gcatatgtaa
     4141 gtcttcactt tttagctgct atggaacgta gcaaagagag tactaagttt aatattcttg
     4201 ctatttgtgc aacaggattt ggtgcagccc aaatgttaag aaatcgtttg gaaacggagt
     4261 ttgggaagcg agtagaagtt gttgatgtaa taggctatta tgaattgaat caagaaaaac
     4321 ttaaaggaat agattttata gtgtcagctg ttgatttatc aaatctatat tttcaaattc
     4381 cagtttttaa agttagtgtg tttcttaaga gtgatgagat ggaaatgatt agaaaagcta
     4441 tggatcagat gcaagtttct agttatgtac aatcatcaaa gattaataaa tttgaaaaca
     4501 acagctttag acagtatttt agtaaagaaa attttttaat atgtactgaa tcagacaagg
     4561 taaatttact tgaaaagatg gttgagagtt tatctgttgg tgaatcaaat gagtttgaac
     4621 aatctttact ttatggaatt aaacagcgcg aagaattaag ttcagttgtt ttttctgaaa
     4681 aaattgcagt tccgcatcct attcagccct ttggtacaga gggaaaggtt tcggttgcaa
     4741 tctgtaaaga ttcgttactc tgggataatc aaagttcata tgtccagcta gtatttcttc
     4801 tatctccatc aatatatggg aacgaaggtt tggcaactgt gactaaaaag atagtctctc
     4861 tgacagagaa tgatgagttg caaaatcagc taatatcttg caataacttt gaagatttta
     4921 ttagcatatt tgagaagata aaataggagg ttcatatgaa tcaagaggaa ctgcaggttg
     4981 cagcatttga aattatcctg cattcgggaa atgcaaggtc agaaatacat gaagcatttg
     5041 caaaaatgag agaaggtagt tttgatgatg cagaaagtaa attaaatcaa tcaaatgaga
     5101 taattcttga agcgcatcat gcacaaacca aactcttgca agaatacgca agtggagtgg
     5161 aaattaaaat tgaaattatc atggtacatg ctcaagatca tttaatgacc actatgacat
     5221 tattagaagt agcaaaggaa atgttagctc tttataagaa agttaactaa atatgtgttg
     5281 ttatataagg aggaaatgat atggataaaa aagaacgaca aaagattgaa caacaacgtc
     5341 gagagatggc tctaactaat acttttttta atcgatatct tcttctacgt tattcaatag
     5401 cactcttctt ttttgggaat atttattggc ttttgaatca gtttattaat ccctcgccta
     5461 ttattatttt ccccattatg ctcatagtat tttctatttt agcaactgtt gaacaattta
     5521 aactctatgg aaataggaaa gaaaagttgg gaataacact aatgtttgtt agaatacaaa
     5581 tacttatttc aataggatta cttgttttaa cttggacaag ttggtttaag aatctttttc
     5641 cgatttttga aaataaccaa gtagcacgtt tatttgtttt tgtagttctt ctattaggtt
     5701 tagttctgag tttgttagac attagaagaa ttaaaaaaat ttataaacga acagataagg
     5761 cttatcaaca atttgtccaa ttggaaaaga actcacttag tttataatcc tgatctagta
     5821 taatttgtat ttgaaactag tctttagaaa gtaaaaatta ttatgtttta ttaaggaggt
     5881 ctatttatgg atcaacaaaa cgggttgttt ggttttcttg aaaaccatgt tatgggacca
     5941 atgggcaaac ttgctcagtt taaagtagtg cgtgctatca cggctgcagg tatggctgct
     6001 gtaccattta ctattgtagg atcaatgttt ttggtattca gtattttgcc acaagctttc
     6061 tcattttggc caattgtggc agatattttc tctgcttcat ttgataaatt cacatcactt
     6121 tacatggttg caaactatgc gactatgggt tctctatctc tttatttcgt tctatcactt
     6181 gcatatgaat tgacaaaaat ttatgcagag gaagaagaac tcaatatgaa tcctcttaat
     6241 ggtgccttgc tcgccttgat ggcttttgtc atgacagtac cgcaaatcat ttttgatggt
     6301 ggaatgatga agactgtgac aagtctaaaa gaaggtgcag taattgcaga tggatgggca
     6361 atgggaaatg gagtcgcacg ttttgggaca acagggattt ttaccgcaat cattatggca
     6421 attgtgactg ttcttattta tcgtatgtgt gttaaacata attgggttat taaaatgcct
     6481 gaagctgttc cagaaggagt ttctcgtgga tttaccgctt tggttccggg atttgttgtt
     6541 gcatttgttg ttatctttat caacggtctt cttgtagcaa tgggaacaga tatttttaaa
     6601 gtcattgcaa ttccatttgg ttttgtatcc aatctgacta attcgtggat tggtttaatg
     6661 attatttatc tattgactca actactttgg attgtaggta tccacggtgc gaacattgtt
     6721 tttgcatttg ttagtccaat tgctcttgct aacatggctg aaaatgctgc tggcgggcac
     6781 ttcgctgttg caggtgaatt ttctaatatg tttgtaattg caggtggttc tggtgcaact
     6841 ttaggactat gtttatatat tgcttttgcc tctaaatctg aacagcttaa agcaatagga
     6901 cgagcatctg tagttccagc cttatttaat attaatgaac cattaatttt tggattacct
     6961 attatctata atccagcctt ggctatacca tttattttag caccaatggt tactgctact
     7021 atttattacg tagcgaattc tctaaacttt attaagccaa ttatcgcaca ggttccatgg
     7081 ccaactccag tagggattgg agctttctta gggacagcag atcttcgagc tgtattagtt
     7141 gctctagtat gtgcatttgc agcattctta gtctatcttc cattcatccg tgtatatgat
     7201 caaaaattgg tgaaagaaga gcaaggtatc taataagtaa aaaagtatac tcgatgatag
     7261 aatccatata gtttaaataa tgagtgttaa tattagcagt gaagaggtct ttttaagata
     7321 ttcttctctg ctttttcata ttttttcgct atgtagggta tgaagcaaaa tagaaagtag
     7381 ttcgaatagt tgataaacag gaaactgctg ttatttaaaa aaaacaataa agtaaagtat
     7441 gttatcgtag aatacgatac aatagtaaaa aagcaaaaag aatgcgtttt atatttgggt
     7501 ttgaggttta taaaatagga taagcgtgct gaaaacttag atatgacaaa caaaataaaa
     7561 tttttaaaag ctacatagaa acatggtata atgtatctaa aggaggtagc atatgtcctt
     7621 agatatagat aaagaaaaga tgacaatcat gggaatagct tttgaaaaca gatccgtttt
     7681 taagagtgtt tggtatgctt taagtacaaa tatgattgaa ggatggcgac ctacggttag
     7741 tgatgttgaa aaattacgag atgaagctct tgctctgggg atgacttaat gaagcgcaac
     7801 tgttatgagt cttatgacta tgttgatccg gataatttat ataccgatcc gggttcttca
     7861 gttctaagaa ataagcagga aggaaaaaag cacgcgagct tgaatatcgt atgattgcta
     7921 gtaagagttt gaaattattt atcaatccta tcttagttaa tagtttaaaa gtagtttgtt
     7981 tcacaactgc ataagcttag aaaagttgaa aagtgataac tctttaataa actcttggtt
     8041 tgttaaaaga tattttgtcc actacatttt ttcaattgac tattatttgt catagatata
     8101 acagatagaa cagatagaac attgcattca gaataatgaa aaacgcatca aaaatggtgc
     8161 gttctgtttt tatgctacca taaaaggagg aaaacaaatt gaaaattttt aagggagagt
     8221 tttatcgaat ctctgtatta acagacaagc tagtaaggtt agaatactct caaactggaa
     8281 gttttgagga tagaacgaca caacttatct ataatagaga ttttggccaa gtttcgttag
     8341 attatatcga gacatcaaac gtactagata ttatgacgga ctattttcat ctgcacttta
     8401 ataaaggaga atttaacgcc gaaaatttat ttatagaatt aaaaggaaat tttgccgtat
     8461 atggtagtcg ctggtatttt ggtgaatcta ttgaaacgtt aaaaggaaca gctcggactc
     8521 tggataaggc agatggagca atctcgttag aagatggaat tattagccga aatggtatag
     8581 ccttattgga tgattctcaa ggatttattt gggatgaaca atctggttat attgagagag
     8641 aaaatcaaat tgacctgtat ttctttgcct atgggcatga ttatagagga gcaatcagag
     8701 acttttacca tttgactggt tcaacaccct tgttgccaag atatgcttta ggcaattggt
     8761 ggagtagata ttggccttat acgtcggatg aatacttgga tttaatagac agatttgaaa
     8821 cagagaaaat tccattatct atcggtgtgt tagatatgga ttggcatata actgacattc
     8881 cagctcgttt tggaagtggc tggacaggat atagttggaa tagaaactta ataccaaatc
     8941 cagaacagtt attgcaacaa cttcatgata gaaagttaaa actctcctta aatgtccatc
     9001 ctgctgatgg gatacgggct tatgaagaag cttatcctca aatcgcaaaa cggttggggt
     9061 taaatgtaga actagaagaa cctgctattt ttgatttttt taatccctct tttagggaag
     9121 cctactttaa agatgttcat tatgagctag aaaagcaggg agtagatttt tggtggattg
     9181 actggcaaca agggacacaa ggtatgctag atccactttg gcttttaaac cattatcact
     9241 atcaggatag ttgtaaaaat gcagaaggtg gtttgatttt atcaagatat gcaggtcctg
     9301 gtagtcaccg ctaccctgtt ggtttttcag gggatactat tattagttgg aattccttaa
     9361 ggtttcaacc ctattttaca gcgacagcat ctaatatcgg ttatagttgg tggagtcatg
     9421 atatcggtgg acatatgttg ggggattatg acgaagagct acaaactaga tggctacagt
     9481 ttggtgtttt tagtccgatt actcgattac atagttctag aagtcctttt aatagtaaag
     9541 aaccttggtt cttttcagaa acaacatcta agattatgaa gaaatacctt cgtttgagac
     9601 atcagatgat tccctatcta tataccatga atgtaaagac acatgaggaa ggtgccccat
     9661 taatcagtcc aatctattat ttctatccag agaatgatga gagctataat gttccaaacc
     9721 aatacttttt tggaacagaa ctgatggtgg ctcccattgt agaaaagatg gatttgacat
     9781 tccaatctgc aaaagtagat gtatggttcc ctgaaggtga atggtatgac ttcttttcag
     9841 agaaaaaata cacaggtggt gtgaagttaa gtgtttatag ggacatctcg actacgcctg
     9901 tgtttgcaaa aagtggtgca atcattccct tggttggttc tgagataggt atgggtgttg
     9961 atttacctga ggttgtagat tggtatgtat tcccagggaa acaacatttt tttgaaatgc
    10021 ttgaagatca aaatggtcaa agatataaaa caagattatc aatcgattgg gaaatgggaa
    10081 tggtagagtt agcattacaa ggagattcta gtatcgttcc aagcaataga aaacatagaa
    10141 ttcattttaa aggaacgaat gtgtctataa ttgaattgcc aaataagaat gatacagcta
    10201 aatttgaatg gaaagataat aaaaggacat ctttaaatga cgaagttttt agactactaa
    10261 agacagcttc tcttccatat gaattaaaag atagattgtt aaatcaattc atcaatgcga
    10321 aaaactctca tgacttaatg aatatcttgc atcatcagga taaggaattg agagggcgtt
    10381 tgttggaaat gatatttact agccaaaact aattgaaata attagaaagt catttgttta
    10441 gtgtatatga agattctgta tggtattcgt tatcactggt cacattgaaa atgtgaaata
    10501 agcacctaca acatagactt tacaacactt catgtttcat atcatggggt gtttttctat
    10561 ttaagtcaaa gcccatcaaa aaatctcact attcatcagg ttaaaggaaa cctaatcata
    10621 gtgagattgt gaattatagt agagtttgta tcgcctcttc aatttgtttt gggtctgttt
    10681 ttgaagaaaa gcgttcaaag acttgcccat ctcgaccgat gagaaactta gcgaaattcc
    10741 attcgattcg ttttcctagt gggccggatt tctggtcttt taaccagaca tagagagggt
    10801 ctgcttcctt accgttgacc ttaatcttgg caaaacgtgg gaaggtggtt tgaaaatgta
    10861 ggctacagaa ggcgttgatt tcctctgcgc tgccgggtgc ttgtcccata aactgattgc
    10921 aagggaaatc caatatttcg aagccctgat cttgatagcg ttcatagagt tcttgaagtc
    10981 cctggtactg gggcgttaaa ccacatccag tagcagtgtt gacaatcaag agaactttgc
    11041 cacgatagct atccaaggga gttgcttggt tgttttggtt caaaacggaa aaatcataaa
    11101 gtgaagtcat gagggcctct tttctttttc tacattgtaa cagtttttac ttttttcgtc
    11161 gagtcggatg gaagatattg ttgaagaata agccttcaat atgatagaaa ccgtttacaa
    11221 ataactttaa aaatggtatg atttaattaa accggtttac ttagttgcta taaatctcta
    11281 atttgagatt tagttcctat tgattttaca atatgtttat tggagtgtat acatgcaaac
    11341 aaaaacaaag aagctcattg tgagtttgtc ttcacttgtt ttatcaggat ttttattaaa
    11401 ccattatatg acagttggag cggaagaaac gactacgaat accattcagc aaagccagaa
    11461 ggaagttcag tatcagcaaa gggatacaaa aaatttagtt gaaaatggtg attttggtca
    11521 gacggaggac ggaagcagtc cgtggacagg aagcaaagct caggggtggt cagcttgggt
    11581 agaccagaag aatagtgcag atgcctcaac tcgagtcatt gaggctaagg atggggctat
    11641 cactatctca agccatgaga aattaagggc agcggttcac cgtatggttc ctattgaagc
    11701 taagaaaaag tataaactgc gtttcaagat taaaacagat cataaagtcg ggattgccaa
    11761 agttcgtatc attgaggaaa gtgataagga caagcgattg tggaattctg caacgacgtc
    11821 aggaacaaag gactggcaga ccattgaagc agactatagc ccgactttag atgttgataa
    11881 aatcaagctg gagttattct atgaaacagg aactgggact gtttccttta aggatattga
    11941 gctggtagag gtagcagacc agccttctga ggactatcaa acagataaac agcttgagga
    12001 aaagattgat ttaccaattg gaaaaaaaca tgttttttct cttgcggact atacttataa
    12061 ggtagaaaat cctgacgttg cttcagtcaa aaatggaatt ttagaacctc ttaaggaagg
    12121 gacaaccaat gtcattgtca gtaaagatgg caaggaagtg aaaaagattc ctttgaagat
    12181 tctagcctct gttaaggatg catacacaga ccgtttggat gactggaatg gcatcatcgc
    12241 tgggaatcaa tactatgatt ctaaaaatga acagatggcc aaattaaacc aggaattgga
    12301 aggaaaggta gctgatagcc tatctagtat ttcaagtcag gcggaccgca cctatttgtg
    12361 ggaaaaattt tcaaattata aaatgtctgc aaatctgact gccacttatc ggaaattgga
    12421 ggagatggcc aagcaagtga ccaatccttc ttctcgttat tatcaagatg aaactgtcgt
    12481 tcgaacagtc agggattcca tggaatggat gcataaacat gtctacaata gtgaaaagag
    12541 cattgttggg aactggtggg attatgaaat cggtacacct cgtgccatca acaatacctt
    12601 gtctctgatg aaagaatact tctctgatga ggaaattaaa aaatatacag atgtgattga
    12661 aaaatttgta ccagatcccg aacatttccg aaagacgact gataacccat ttaaggctct
    12721 aggtggaaac ttagttgata tgggaagagt aaaagtaata gctggtttac tgcgtaagga
    12781 tgatcaagaa atttcttcta ccattcgctc gattgagcaa gtgttcaagt tggtagacca
    12841 aggtgaaggt ttttatcaag atggatccta tatcgaccat accaatgttg cctatacggg
    12901 tgcttatggg aatgttttga ttgatggcct gtctcaactg ttgccagtca ttcaaaagac
    12961 caagaatcca atcgataaag ataaaatgca aaccatgtac cactggattg ataaatcgtt
    13021 tgctcctttg ctggtgaatg gagagctgat ggatatgagt cgtggacgct cgatcagtcg
    13081 tgcaaatagc gaggggcacg tggccgcagt agaagtacta agagggattc accgaatagc
    13141 ggatatgtct gaaggagaaa ccaaacaacg tttgcagagt cttgtgaaga ccattgttca
    13201 atcggatagt tattatgatg tctttaagaa tttgaagact tataaggata tcagtttgat
    13261 gcaatccttg ttaagtgatg caggagtcgc aagtgttcca agaacaagtt acctatctgc
    13321 ctttaacaag atggataaaa cagccatgta caatgcagag aaagggtttg gatttggctt
    13381 gtcactcttt tccagtcgta ccttgaatta cgaacacatg aacaaggaaa ataaacgtgg
    13441 ttggtatacg agtgatggga tgttctatct ttacaatggc gatttgagtc actatagcga
    13501 tggctactgg ccaacagtta atccatataa gatgcctggt acaacagaga cggatgctaa
    13561 gagagcggat agcgatacag gtaaagtttt accgtctgct ttcgttggaa cgagcaaact
    13621 agatgatgcc aatgcgacag caaccatgga tttcaccaac tggaatcaaa cattgactgc
    13681 tcataagagc tggtttatgc taaaggataa gatcgccttt ttaggaagca atatccaaaa
    13741 cacttcaaca gatactgctg caactacaat tgaccagaga aaactggaat caagtaatcc
    13801 atataaagtc tatgtcaatg ataaagaagc ctcccttaca gaacaagaaa aggattatcc
    13861 tgaaacccaa agtgtctttt tagaatcatc cgattcgaaa aagaatattg gttacttttt
    13921 ctttaagaag agttcaatca gtatgagtaa ggctttgcaa aagggagcct ggaaggatat
    13981 caatgaagga cagtcagaca aggaagttga aaatgaattt cttacgatta gtcaggctca
    14041 taagcaaaat ggagattctt atggctatat gctcatccct aacgtgggtc gtgccacctt
    14101 caatcaaatg ataaaagagt tagaaagaag cctcatcgaa aataacgaaa cccttcagtc
    14161 tgtttatgat gccaaacaag gagtttgggg cattgtgaaa tatgatgatt ctgtctctac
    14221 tatttccaac caattccaag ttttgaaacg tggagtctat accattcgaa aagaagggga
    14281 tgaatataag attgcctact ataatcctga aacccaggaa tcagctccag atcaggaagt
    14341 ctttaaaaag ctagagcaag cagctcagcc acaagtacag aattcaaaag aaaaggaaaa
    14401 atctgaagag gaaaagaacc attcggatca aaagaatctc cctcagacag gagaaggtca
    14461 gtcaatcttg gcaagtctag ggttcttgct acttggggcg ttttatttat tccgtagagg
    14521 aaagaacaac taatttgttc atcatctaga tgaattacat gaaactgtgg aaaatagaaa
    14581 aaatccgaag aaggccaaat atcttcggat ttttctttta aaaaaggata agttgatact
    14641 tatccttttt acttcattat gtgactatag cgttttgaaa ctagaatagg acatcataac
    14701 tgctaaaaga tttctataaa ttcatttgat tttcctaatc aatttattcg tatcctattt
    14761 cactctacta tattagtccg tctcgcacct cacggagcga gacaaaacaa ccacccgcta
    14821 tgcgggtgcg cgtcgaaggt tataccaaaa aaactccaaa cgcgatacaa taaaggtgtt
    14881 caatccactt gtaaagcgaa aggagaaaaa atatggcaca aaaggctcat agtttatctc
    14941 acacaaagtg gaggtgttct atcacattgt gttcacccct aagtatagac gaaaagtcat
    15001 ctata
//
LOCUS       DAVBCA010000052        14432 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.052, whole genome shotgun sequence.
ACCESSION   DAVBCA010000052 DAVBCA010000000
VERSION     DAVBCA010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14432)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14432)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14432
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.052"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..2288)
                     /locus_tag="VQU19_001612"
     CDS             complement(<1..2288)
                     /locus_tag="VQU19_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec-dependent serine-rich glycoprotein
                     adhesin"
                     /protein_id="HET2480836.1"
                     /translation="MFKVMRGGVDTTQVMTETVEDKVSHSITGLDILKGIVAAGTVIS
                     GTVATQTKVFTNESAVLEKTVEKTDALATNDTVVLGTISTSNSASSTSLSASESASTS
                     ASESASTSASTSASTSASESASTSASTSISASSTVVGSQTAAATEATAKKVEEDRKKP
                     ASDYAASVTNVNLQSYAKRRKRSVDSIEQLLASIKAAVFSGNTIVNGAPAINASLNIA
                     KSETKVYTGTGLDSVYHVPIYYKLTVTNDGSKLTFTYTVTYVDPTTRALGNLSKMGHG
                     YSIYNTGTSIQTMLTLGSDLGTPSDVKNYITDKDGVLVRSYNTSTMTTWGSGYTWGNG
                     AQMNGFFAKQGYGLTSSWTVPITGTDTSFTFTPYAAKTDNIRTNYFKGRGKVVESSTT
                     SQSLSQSKSLSVSASQSASASASTSASESASTSASASASTSASASASTSASASASTSA
                     SASASTSASESASTSASASASTSASASASTSASASASTSASASASTSASASASTSASA
                     SASTSASASASTSASESASTSASESASTSASASASTSASASASTSASASASTSASASA
                     STSASASASTSASASASTSASESASTSASASASTSASASASTSASASASTSASESAST
                     SASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSA
                     SASASTSASASASTSASESASTSASASASTSASASSSTSASASASTSASASASTSASA
                     SASTSASASASTSASESASTSAS"
     gene            complement(2286..2399)
                     /locus_tag="VQU19_001613"
                     /pseudo
     CDS             complement(2286..2399)
                     /locus_tag="VQU19_001613"
                     /inference="COORDINATES: protein motif:HMM:TIGR03715.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="KxYKxGKxW signal peptide domain-containing
                     protein"
     gene            complement(2637..3098)
                     /locus_tag="VQU19_001614"
     CDS             complement(2637..3098)
                     /locus_tag="VQU19_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000514209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2480837.1"
                     /translation="MGKERRKQGNLERKKRVVKKRKIPLEELKAFVEAHPDAFLREIA
                     ARFDCALPSVWAVLKQIKVILKKTTSFREQKPEKVSEFLDILDNLKDLPVLYIDETGI
                     NRYLYRPYAGAPRGEKVYDKISGRRFERTNEVEQKLNGSFLIRYIDSQIRE"
     gene            complement(3065..3208)
                     /locus_tag="VQU19_001615"
     CDS             complement(3065..3208)
                     /locus_tag="VQU19_001615"
                     /inference="COORDINATES: protein motif:HMM:NF013842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET2480838.1"
                     /translation="MAYSTDFKQGALDSIKEGHSHVEAAKFFGVGVRTLFTWEKKDVN
                     KGT"
     gene            3477..3857
                     /locus_tag="VQU19_001616"
     CDS             3477..3857
                     /locus_tag="VQU19_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET2480839.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            3956..4177
                     /locus_tag="VQU19_001617"
     CDS             3956..4177
                     /locus_tag="VQU19_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HET2480840.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            4194..4508
                     /gene="trxA"
                     /locus_tag="VQU19_001618"
     CDS             4194..4508
                     /gene="trxA"
                     /locus_tag="VQU19_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HET2480841.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            4815..5348
                     /gene="queF"
                     /locus_tag="VQU19_001619"
     CDS             4815..5348
                     /gene="queF"
                     /locus_tag="VQU19_001619"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HET2480842.1"
                     /translation="MKHQSALVVFSGGQDSTTCLFWTMQHYETVEAVTFAYGQHHHLE
                     IQITREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDNR"
     gene            complement(5602..6270)
                     /locus_tag="VQU19_001620"
     CDS             complement(5602..6270)
                     /locus_tag="VQU19_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HET2480843.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLSN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
     gene            complement(6381..6935)
                     /locus_tag="VQU19_001621"
     CDS             complement(6381..6935)
                     /locus_tag="VQU19_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HET2480844.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLFDHLGNPSPEIRNVLLNQGL
                     HYLSKEKDTRGFSSQYGWVHAFAHGADLLTEVVCHPGFPKNRVHEVFEILGQLFKRMS
                     IRFTDDEDWRLARVIYEPILQGKLAQEQVASWIKTVDFPIEEREDFYKFSNFRSCLVE
                     VYVQLDQRNSLQDELKEAIQSFQY"
     gene            complement(7181..8977)
                     /gene="pepF"
                     /locus_tag="VQU19_001622"
     CDS             complement(7181..8977)
                     /gene="pepF"
                     /locus_tag="VQU19_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HET2480845.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYGFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVAADEEVLDRLGKLPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDATLTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKHSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIISYSAELGE"
     gene            complement(8988..9731)
                     /locus_tag="VQU19_001623"
     CDS             complement(8988..9731)
                     /locus_tag="VQU19_001623"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HET2480846.1"
                     /translation="MQQYFVKGSAVSPVTIEDRETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFITQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNVVPSIHLFENKADFLAQLDQ
                     FDRILVAYEEAAKEGEAAALIKAVTGLEKGAKLLFIFGPEGGLSPAEIENFEAKGAVL
                     AGLGPRILRAETAPLYALSALSVLVELEK"
     gene            complement(9733..10683)
                     /locus_tag="VQU19_001624"
     CDS             complement(9733..10683)
                     /locus_tag="VQU19_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HET2480847.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYMGNVD
                     RFGEIFPEVEQQEEIVVTAYYPDTVDMTVVEADLQARLAELTDFMDLGELKIGTTALA
                     EEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMS
                     LFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNTG
                     MENIHVAAGDLLKGVEIEADVIVANILADILIHLTEDAYRLVKDEGYLIMSGIIKDKW
                     DMVRQSAESAGFFLETHMIQGEWNACVFKKTKDISGVIGG"
     gene            complement(10821..11249)
                     /locus_tag="VQU19_001625"
     CDS             complement(10821..11249)
                     /locus_tag="VQU19_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET2480848.1"
                     /translation="MELEISDFQGCKIALFCGDKLLTILRDDKDDIPCPNMWELPGGG
                     REGDESPFECARREVYEELGIHLDEDCLLWSKIYPSVIFKGKKSVFMVGQLRQEQFDN
                     IIFGDEGQGYQLMNVEEFLSSSQVVPQLQERLKDYLKVSD"
     gene            complement(11230..12318)
                     /locus_tag="VQU19_001626"
     CDS             complement(11230..12318)
                     /locus_tag="VQU19_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HET2480849.1"
                     /translation="MKKIGTYLVYVLAVVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQLKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENLLAELEKEMLEGTEDGTRNF"
     gene            complement(12337..12807)
                     /locus_tag="VQU19_001627"
     CDS             complement(12337..12807)
                     /locus_tag="VQU19_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HET2480850.1"
                     /translation="MATYGFLDVLEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNEEDYLTVIPYLPKKGFSREFLAYF
                     VLFLKDTAEVGLDVLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            complement(13098..13550)
                     /locus_tag="VQU19_001628"
     CDS             complement(13098..13550)
                     /locus_tag="VQU19_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HET2480851.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            complement(13587..13766)
                     /locus_tag="VQU19_001629"
     CDS             complement(13587..13766)
                     /locus_tag="VQU19_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HET2480852.1"
                     /translation="MPMTQKEMVKLFTAHGWIKTRGGKGSHIKIEKQGERPITILHGE
                     LNKYTERGIGKQAGL"
     gene            complement(13903..14082)
                     /locus_tag="VQU19_001630"
     CDS             complement(13903..14082)
                     /locus_tag="VQU19_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480853.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSGPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            complement(14247..>14432)
                     /locus_tag="VQU19_001631"
     CDS             complement(14247..>14432)
                     /locus_tag="VQU19_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480854.1"
                     /translation="IFTKQIRHWILSDQVISGKRKLFFREDTPKEILDLYENIKSKLD
                     FAYQEVHSNNGLKKYEK"
BASE COUNT         4196 a         3287 c         2765 g         4184 t
ORIGIN      
        1 gacgcactcg ttgaggctga ctcagacgca ctcgttgagg ctgaagctga cgcactcgtt
       61 gatgctgaag ccgaggcact ggttgacgct gaagctgagg cgcttgttga tgctgaggct
      121 gatgcgcttg tgcttgatga agctgaggca cttgttgatg ctgaggctga cgcactcgtt
      181 gatgcagatt cagacgcact tgtgcttgct gaggctgacg cactggttga tgcggaagct
      241 gaggcgcttg tgcttgctga agccgacgca ctcgttgagg ctgaagctga agcgcttgtc
      301 gatgctgagg ctgacgcact tgtcgacgct gaagctgaag cactggttga cgctgaagct
      361 gaggcactgg ttgacgctga agctgacgcg ctggttgagg ctgaggctga ggcgctagta
      421 cttgctgact ctgatgcact ggtacttgct gaggctgacg cacttgtgct tgctgaagcg
      481 gacgcactcg ttgatgctga agctgaagca ctggtacttg ctgactctga tgcactggta
      541 cttgctgagg ctgacgcact tgtgcttgct gaagccgatg cactcgttga tgcggaagct
      601 gatgcacttg ttgatgcgga agctgatgca ctcgttgatg ctgaagctga ggcgctagta
      661 cttgctgagg ctgaggcact ggttgatgcc gattcagatg cactggttga ggccgattca
      721 gacgctgagg tacttgctga agctgacgca ctggttgacg ctgaagctga tgcactggtt
      781 gacgctgagg ccgaagcact ggtacttgct gaagccgacg cactggtgct tgctgaagcc
      841 gaggcgctag tgcttgctga agccgacgca ctcgttgatg cggaagctga cgcactcgtt
      901 gatgcagatt cagacgctga ggtacttgct gaagctgagg cactcgttga tgcggaagct
      961 gacgcactcg ttgatgctga ggctgaggca cttgtacttg ctgaggctga tgcgctggtt
     1021 gaggccgatt cagaagctga ggtgcttgct gaggctgagg cgctttgact agcacttact
     1081 gagagtgact tagactgtga aagtgactga ctggtcgtgc tagattcaac tacctttcct
     1141 ctacccttga agtagttagt tctaatgtta tctgttttag cagcgtaagg ggtaaatgta
     1201 aaggatgtat ccgttccagt aattggtaca gtccaagatg atgttaatcc atatccttgc
     1261 ttagcaaaga aaccattcat ttgggcacca tttccccaag tatacccact accccacgtc
     1321 gtcattgtag atgtattata ggatcgaacc agtacaccat ctttgtcagt aatgtagttc
     1381 tttacatctg aaggggtacc aagatcactg ccaagggtta acattgtttg tattgaagta
     1441 cctgtattat agatagaata cccatgaccc atctttgaaa gattaccaag agcccttgtg
     1501 gtaggatcta catacgtaac cgtataggta aaggtcagtt ttgaaccatc atttgtcact
     1561 gtcaatttat agtaaattgg aacatgatat accgaatcta aacctgtacc tgtataaact
     1621 tttgtctcac ttttagcaat gtttagactt gcattaattg caggggcgcc atttacaatc
     1681 gtattgccag aaaaaacagc agcttttata gaagccagca attgctcgat ggaatccact
     1741 gaacgcttgc gtcgcttagc ataagattgg agattgacat ttgtaactga tgctgcataa
     1801 tcactagctg gtttcttacg atcttcttcg accttcttag cagttgcttc tgtagcggca
     1861 gctgtttgtg atcctaccac agtagatgat gcagagatac ttgtcgaagc cgatgtactt
     1921 gctgattctg atgcacttgt actcgctgag gtcgaagcgc tggttgaggc tgactcagat
     1981 gcagatgtac ttgccgactc tgaagctgac aaactagttg aactcgctga attacttgta
     2041 gatatcgtac ctagaactac tgtatcattt gttgccaaag catccgtttt ctctacagtt
     2101 ttttcaagta ctgccgactc atttgtaaat accttcgttt gagttgcaac ggttccactt
     2161 atgacagttc ccgcagcaac tattcccttg aggatatcaa gcccagtaat tgaatgactt
     2221 actttatctt ctaccgtttc ggtcatgacc tgagtagtat caacaccacc acgcatgacc
     2281 ttaaacaagc caaaaagaga agtcgaggcc cgtagccaat gcttccctga tttgattaat
     2341 ttgaaccgag ttactcggtc tgtttctcta tattcaccct tctgacgtct aaaaaatatt
     2401 ttgaaatttc ctttcgagta ttattttcat gtatggatat aaataaatta ccatactata
     2461 attatagaat agggaaccca aaatagcaag aaacttgagg tatttttgct aaaaaaaaaa
     2521 agcattttac tattttatat atatattata agataagttt tttataaaga cacgcaaatg
     2581 agtataaatc agctaatttt tggtttatat tcctattttt atgcataatt attctttcat
     2641 tctctaattt gtgaatcaat atatctgatt agaaaactac cattgagttt ttgctccacc
     2701 tcattagtcc gctcaaaacg ccgtccgcta atcttgtcat agactttctc ccctctagga
     2761 gcccctgcat aaggacgata gaggtagcgg ttgattcccg tttcgtcaat atataggact
     2821 ggtaaatctt ttaggttatc caaaatatca agaaactcag aaactttctc aggcttttgt
     2881 tccctaaaac tggtcgtctt ttttaaaatg accttaatct gctttaaaac tgcccatacg
     2941 gagggcaaag cacaatcaaa acgggccgca atttcccgta aaaaagcgtc tggatgagcc
     3001 tctacaaagg ctttcaattc ttctaaaggg atcttacgct ttttgacgac tcgctttttc
     3061 cgctctaagt tcccttgttt acgtctttct tttcccacgt gaagagagtt ctgacgccaa
     3121 caccaaaaaa cttggctgcc tcgacatgac tgtgcccctc tttgatggaa tctaatgctc
     3181 cttgtttaaa atcagtacta tatgccatag ctttattaga ccatgcttat tttaaactaa
     3241 gcaactatag atagagaaat gaaataaaat ctaaattcga atgtgataag gagttagaaa
     3301 ttgaaacaat aggattcccc cattattcac acaaaaataa aaccactaaa aaacagagct
     3361 tgccagcatt cttgaaaagt agtataatta ttgcatgcgc aatcatcttg tgacgcagag
     3421 actgcccgtt aatggacttt cttctatatt atgactctaa aaagaaagga gacactatga
     3481 cctatttgga aaaatggttt gacttcaatc ggcgtcagaa agaaattgaa agtctcttgg
     3541 aagagaccat tgcccaacag agcgagcaaa gtctgacctt gaaagagttc tacctgctct
     3601 actatctgga cttggctgaa gaaaaatctc tacgccagat tgacctgcca gataaacttc
     3661 atctgagccc gagcgcagtt tctaggatgg tggctcgctt ggaagctaaa aattgcggtc
     3721 tactcagtcg catgtgttgc catcaagata gacgctctag ttttatctgc ctgacaaatg
     3781 atgggcaaaa gacactggcc tcgctacaaa agactgtcga agaaagcttg gaagcaggtt
     3841 tggatttctt gatttaagat gattttaaaa aaagttgcgt gcgcaatcat ttttcttgac
     3901 attctctttt ataaggagta aaataaagtt agcattaaac aaaggagttt taaatatgat
     3961 tgaaattacc tatatagatg ccagcaagaa cgaaagaact gtgactttcg agtcttatga
     4021 agactttgaa cgttcacaac aagcttgcct tatcggcgtc gcagactact accctgtcca
     4081 aaaattaact tacaagggtc ataatttgga ctaccatggg acttatggag atatcttctt
     4141 ctatctcatg aaacaagatt taagccaata taactaaaaa aaggagaaat acaatggcaa
     4201 aagcaattac agatgcaaca ttcgaacaag aaacaaaaga cggtttggtc ttagtagact
     4261 tctgggcaac ttggtgtggt ccatgtcgta tgcaaggtcc aatcttggac aaattgtctg
     4321 aagaactttc agaagatgtc ttgaaaatcg ttaaaatgga cgttgatgaa aatccaaaca
     4381 cagctcgtgc ttttggaatc atgtctattc caactcttct cttcaaaaaa gacggccaag
     4441 ttgtcaaaca agttgcaggt gttcacacag cagaacaaat caaggccatc attgctgaat
     4501 tgagctaatc aaacgagaga ccaagtactt tctttggtct cttttttctt gccctttgcc
     4561 atttttcaaa aaatatgcta gactatagta gattgaaact agaatagtac acctctactt
     4621 ctaaaacatt gttaaaaatc gatttgactg tcctgatcga tttgtcctgt ttttatttca
     4681 ttttactata taagtagaat attacgatgt ttgggatatg ccatcgctaa aaaaaaactc
     4741 gatttggtat tttttagttc cctaatggga gctttttgcg tgctctgaac atttcccatt
     4801 ttggaaggag tactatgaaa catcaatcag ccttggtcgt ctttagtggc ggtcaagatt
     4861 caacaacctg ccttttctgg accatgcaac actatgaaac agtcgaagct gtcacctttg
     4921 cctacggcca acatcatcac ctcgaaattc aaattactag agaaatcgct aaggaacagg
     4981 gcattcgtca ccatatcctc gatatgtctc tgctgggaca aatcactgct cagccagact
     5041 ttgcgacgat tcatatttcc tacattcctg acaagctctg tgtcgagtca aaatccctca
     5101 aactatatct atttagctac cgaaaccacg gagatttcca cgaaaactgt atcaacacca
     5161 tcgggaaaga cttggtcaac ttgctagacc ctcgctattt agaagtctgg ggaaaattca
     5221 ctccgcgcgg tggcatttca atcgacccct actataacta cggtaagcaa ggaactaagt
     5281 atgagggctt ggcagaacaa cgcctcttcc aacacgacct ttatccagag aaaattgaca
     5341 accgctaaag tcatactcaa tgaaaatcaa agagcaaact aggaagttag ccgcaggtta
     5401 ctcaaagcag tgtttgaggt tgtagataaa actgacgaag tcagatcaaa acactgtttt
     5461 gaggttgtgg atagaactga cgtagtcagt aaccatacct acggcaaggt aaagctgacg
     5521 tggtttgaag agattttcga agagtatcat acgaaaaagc cctgttcctc aagatgagga
     5581 gcaaggcttt ttgagtttca attattcttc tgttccaagg aaattttttg caacaagggc
     5641 tgcaagaact ccaccagcga ttggtgcaag gatgaaaatc caaacttgtt gaagggctgc
     5701 gccgcctacc aagacagctg gtgccaagct acgagctggg tttactgaaa gtccagtaat
     5761 cttcaatccg acaagaatca tcgccatcaa tgacaaaccg attaccaaac cagcaatcgc
     5821 gccattgccc ttgctttctg aagtcacagt catgataacc aatacaaaca agaaagttgc
     5881 gatgacttca aacaagaaac caccaaagac agtgacaccg tttgccaagg cattttcacc
     5941 aagactagca gttgacatac ctgaattact caagaggaag aagactgcgc cagaagcgat
     6001 gaaagctcca acaacctgac caaggatgta gtttacaagt tctgaagatg acaaacgttt
     6061 gtttacaaac atagcaatcg aaacagccgg gttcaagtga gcacctgaaa cagttccgat
     6121 tgagtaggct gccaccacga ttgccaaacc aaaggcaaag gcgattccaa ggtgaccaag
     6181 gccatcaaga ccatttccaa aaacaacagc tcctgttcca acgaacacaa gcatgaacgt
     6241 accgattaac tcagcaacaa attttttcat tttctttctc cttttttcaa aaactagata
     6301 ctagtctatc aaaagtagga aagggtttca agaaaattga ttggaaattt tttgaaaatc
     6361 atagaactat tagctaatct ctagtattga aaagactgga tagcttcttt caactcatct
     6421 tgtaaactat ttctctggtc aagttggaca tagacttcca ccagacagga tctaaagttg
     6481 gaaaatttgt aaaaatcctc cctttcttct atcggaaaat caacagtttt tatccaagaa
     6541 gctacttgtt cttgcgctaa cttcccttgt aaaataggtt catagatcac tcttgctaaa
     6601 cgccaatcct catcatctgt aaagcgaatc gacattcttt taaataattg gccaagtatc
     6661 tcaaatactt catgaactct gtttttagga aagcccggat gacaaaccac ctctgtcagt
     6721 aaatcggctc catgtgcaaa agcatgaacc caaccatact gacttgaaaa accccttgta
     6781 tccttttctt ttgaaagata gtgcaagcct tgatttaaaa ggacattacg aatttctgga
     6841 gaaggatttc ccaaatgatc aaacaaccac tggatttctt cctggttata atttggtttt
     6901 tcttctgcta tttttcttag taaatcttga tacatggtca atacctctac atttctagca
     6961 actgttcaaa aaggcagtct taaatgactc aatattgaat tctcaattaa atacaatctg
     7021 atataaaatg acgtaaataa ctatcaatac cagttctaca gtaagttcaa atttaacatc
     7081 acgatcttca acgacatttt tgaaaatagc tacaactaag acaaatagaa tgacgcttaa
     7141 caagcccata aacatcattc taaaaaattt ttctattccc ctactctccc aactcagcac
     7201 tataggagat aatctggtca actgtgtcag acaagaattg gatggtatca cggagtggtt
     7261 tgtctgttga aatatcagca ccgataatca tggctgactc aagtggtgtc ttgctaccac
     7321 ctgatttgag gagattgagc cagtcttcag ctccagtttc agaatgtttt agatgaaggt
     7381 aaccagcagt cgagataact agtcctgctg agtaagtgta actatacaag cccatatagt
     7441 agtgagcttg gcgcatccaa gtcagagttg catcatcgtc aatttcaata gcatctcccc
     7501 agaaatccgt caaaacttcc ttcataatgc tgttgagctt gcttgctcca aaggtctccc
     7561 cttcttcaat caatgtatac accttacgct ggaaggcggc ttccaagagg tgggtgataa
     7621 agttatggaa gtaggtgtct gtcaagcgat gagccagagc gaagcgtttt tgacgtgggt
     7681 cattagactg gttctccaag taatcactga gtagcaattc attgaaggtt gacggtgctt
     7741 caacatagta ggtcgacata tgggcattga agtaactttg atgattgtct gaaaagatga
     7801 attgaccaga atgcccgatt tcatgaatca aggtatagac atcgctcaaa cggcctgtcc
     7861 agctcatgag tacataaggg tgtacgcgat atgggtccgc cgcataacca ccggaatcct
     7921 tgccactgtt agcagcaaag tccacccagc gctcttcttg gtaacgagca acttcctgac
     7981 aatattcttg ccccaaaggt tctaccgact tcatgaccaa atcataggca tcgtcaatag
     8041 tcacttcagg attcagggcg ctgtccaagt ccaatttcca gtctgcaaag gtcatctttt
     8101 caagaccatt taccttggca acatgcttga ggtatctctg agcgactggt gcaaagtcct
     8161 tcatgatgag gtcaatctgg cggtcaaaca tgacacggtc cacttcttgt tcagctagaa
     8221 gatagtcaaa gacagagtcg tatcccttca tatcagccaa gagtttttca gacttgacct
     8281 gagccagata ggctgctgca gccgtatttt ggtgcttacg aagtccctct gagaaggaac
     8341 ggaaggattt ctcacgaacc tcagcatcct catggttttg gtagaaattc tcataggtca
     8401 caaagctgtt tttgtaggtc ttgccatggg cttcaaagtc agccatttca aaatccccag
     8461 ctcgcatctt agtataaatg tcctgcggac tgtagaaaac ttcaccgaga tttgtcaagg
     8521 ccttctccac atctgcccct aagtagtggg cttttttgat tttagcctga cgaatggcag
     8581 ctgttaaatg tggcaattta cccaaacgat ccaagacttc ctcgtctgct gccaccaagg
     8641 catcgtcaaa aaaggtcaag gctacgctgg catctgtttc aaattccatc ccagcttgag
     8701 caatatttgc aaattcgtca ttgctatagt ccgtcgtctg aggcataaaa ccatagttgc
     8761 caatatggct catctgaatg tagatctgtt ccaattccgc aaaggccttc tcgaaatcct
     8821 caaaagtgtg aagattgccc ttgtaatcac ggctaaactg gttgatgtct tcgcgagctt
     8881 tctcgattgc acgcaagaaa tcctcacggt cttggtatag agctgttaaa tcccaaagtt
     8941 ccttctctgg aaattctgaa cggtgttttt gttccatttt cttcctctta tttctctaat
     9001 tctactaaaa cactaagggc tgataaggcg taaagcggtg ctgtttctgc tcttagaatg
     9061 cgagggccaa gtcctgccaa aacagctccc ttagcttcaa aattttcaat ttccgcaggt
     9121 gacagaccac cttctggacc aaagataaag agcaatttgg ctcctttctc gagtccagta
     9181 actgctttta taagagcagc ggcttctcct tctttggccg cctcttcata ggctactaag
     9241 atgcggtcaa actggtcaag ttgggctaga aagtctgctt tattctcgaa aagatggata
     9301 cttggaacaa cattacgctt actttgctct gctgctccaa gagcaatttt ttctagtttt
     9361 tcaacctttt tacccaattt cttgccatcc cacttagcaa cggaccaatc ggcagggaag
     9421 gcccaaatct ggctggcacc tagttccgtc accttttgag tgataaactc caacttatct
     9481 cccttgggaa atccagatgc gatggtcact tggactggta gttccacatt gtcatttaat
     9541 tcttggacca actcaaactg acgattttcc atatccagca cgcgcgccaa gcgcttgatg
     9601 ccatcatcaa agactaaggt aacctcatcc tcttctttca agcgcataac ctgaaacata
     9661 tgcttgctgg tttccctgtc ctcgatggtg acaggagaga ctgcactccc cttgacaaaa
     9721 tactgttgca tgctagcctc caatcacacc tgaaatatcc ttggtcttct tgaagacgca
     9781 ggcattccat tccccttgaa tcatatgggt ttcaaggaaa aatccagctg actcagccga
     9841 ctggcgcacc atgtcccact tgtccttgat aatgccactc atgatgaggt agccttcatc
     9901 ctttaccaag cgataagcat cctccgtcag atgaatgaga atatccgcca agatattagc
     9961 cacgatgaca tctgcttcaa tctcaactcc cttaagcaag tctcctgctg ctacatggat
    10021 attttccata ccagtgttga gctcaatatt ttcctgagcg acacgaaccg ccacatcatc
    10081 caagtcatag gcgaaaatct ccttggcacc taggagtgag cttgcaatag aaagaacccc
    10141 tgaaccagtc cccacatcta gcaccgtttc gccaccacga agaacctgtt ccaaggcaaa
    10201 aaggctcatc ttggtagttg ggtgggttcc agtaccaaaa gccatgccag gatccagctt
    10261 gataattttt tctcccgcag tcgcctcata gtctgtccaa gagggaacga tggtcaaatc
    10321 atgagtgatg cgagcaggtt catagtattt cttccagttg tctgcccagt cttcctcagc
    10381 caaggcagtc gtacctattt ttaactctcc caaatccata aaatccgtca attctgctaa
    10441 gcgagcctgc aagtccgcct caaccactgt catatccacc gtgtcagggt agtaggctgt
    10501 cactacgatt tcttcttgct gctccacctc tgggaaaatc tcgccaaaac gatccacatt
    10561 tcccatatag tccatgctgt cttcaatcgc gactccttgc gctcccagct caatcaagag
    10621 attggaaacc aactcctctc cctcacgctt cactgtaact tttaactctt gccatgtttc
    10681 cattattaag ataccaagcc cgtaaaacac aaaaccaaaa taggaaattc tctgaagacg
    10741 cttgtgtcta agagaagttt atctttttgg cacagtgttt agggcgggtt cagtttagaa
    10801 atgtaactga accatccttt ctaatcactt acttttaaat aatcttttaa tctctcttgc
    10861 aactgaggca caacttgact ggaactaaga aattcctcaa cattcatcag ctgatagccc
    10921 tgtccttcat ctccgaagat gatattgtca aattgttctt gtcttagctg accaaccata
    10981 aagaccgatt tcttgccttt aaaaattacg ctaggataaa tcttgctcca aagcagacag
    11041 tcttcatcta aatgaattcc cagttcctca taaacttcac gccgagcgca ttcaaaaggg
    11101 ctttcgtccc cttcacggcc accacctggc aactcccaca tgttgggaca agggatatcg
    11161 tccttgtcat cacgcaaaat cgtcagtagc ttatccccac aaaagagggc aatcttgcaa
    11221 ccttggaaat cagaaatttc tagttccatc ttcagttcct tctaacattt ccttttccag
    11281 ctctgctaac aagttttcat aatagcgttt ctcgtccctc aacattcgac tactatccat
    11341 tttctgtcta gcaatcttga gagccttacg agttcgatct acatctttct tcacctttaa
    11401 ttgataccag gcttgtatca cttgaagatt ggacagtttg agagacagaa acgatttgac
    11461 ctgtcgaata ctagcatatt gctccgcttg ctcaaaatct ccttccaaca aggcgatatg
    11521 aagcagggat agttgggcaa ctgtctgcat catcggagta gttgtcctct caagtaatgc
    11581 ttgaaactgc tgtttagcta cttcttcctt cccttccaaa atggaaactt caccttgcat
    11641 acctaataca ccatccgcaa aactccctcg tgcatcctca ggaactgctt gaacaaagtc
    11701 tttcaaatca tattcttgag gagccagcaa agtttgagca gaatgtctca ataccaggta
    11761 ggcgtatttg gtattttcag ggtgttgtag taattcccaa atttttgctc catcggtgat
    11821 gtcgactggc aaaatgttat ttaggaagaa agataaatta agaaaaatcc aagtccctgc
    11881 aaaataccag cttcttgtca aaaatccaaa cactatcgcc aataatatca agccgagatg
    11941 aaccatcaag cctcctgaaa gcatcaggat gattctttga tcgctttcat cctcttttaa
    12001 accaatgtat tgagcaccaa catttttcag aatggctgtt ctactaagat gaaacctgcc
    12061 tgactttttg gtcaaaataa aatgtcctaa tccaaaagcc accagccgat agcctgtcaa
    12121 gtagccacaa aaagcatgac ccagctcatg aagaataaag attaaataca tgcttagaag
    12181 agcgaaggca taaccaaaag taaaggctaa aactgcggaa taccccaact ctgcaaatgc
    12241 gattgttcca caagcaaaag ctagcataat aaagacaaca gctagcacat aaaccaaata
    12301 agtcccaatt ttcttcataa cacctccaac caactcctag tatcttggat aaggataaaa
    12361 ttctccctct tccaagccaa cttttccttc ttcaaagact tcttggttcc attccatgac
    12421 aaattcctct gcttctgggt cttccaaaaa gtccatgagg acatctagcc caacctcagc
    12481 agtatcttta aggaaaagca caaaataagc taaaaattca cgggaaaatc cttttttagg
    12541 caggtaagga ataacagtca aatagtcttc ctcattgact gttgacttag caggattgta
    12601 gaaaaggacc gcttcctcaa aaagaatgtc atctgatgaa acctctccgt cttcatccac
    12661 catctccaca cctgcagcat tttgcgcttc caatagaaaa ctcacttcta ccgcatggtt
    12721 gcgtttgtcc cagctaatct caaagtcaaa gggaaagttc ttgtccaact cttcctctaa
    12781 aacatctaaa aatccgtatg ttgccatttt gtcctctttc tatgcgactc tttaatcgcc
    12841 ccgattgctc ggaaatatgc taaaatagat actaccatct taccacaaaa ttattttatg
    12901 tcctaattat accatattac ctcatttaaa cccttggtat cagtgatttt cttaaaagtc
    12961 tgatttcttc atttctcata aaaatcaata taaaaagccc tcgaaagggc taataaatct
    13021 ataaaatcaa taggcgagta actagcacaa gtggacgtgc ttttttattg actattacca
    13081 cgataccacg cttaatctta ggcttgaact ttcttatctg caatagcgtc tgtcaaagtc
    13141 tgagaaaagt taagtcccat ttctcgtccc aacttatctg cccattttgg tatggtcaaa
    13201 gtctttttaa tgggttcctg acttcctagg tattctgata catcaacaga taccatagaa
    13261 ataaaagatt tatcaaggtc ataggttgac acgaaatctt catcatcttt aaaaggatca
    13321 ttatcaatta aagacaagct attgatatct gatggctgag gtaactctcc atcactctct
    13381 atcaaatctg caacagttat ccctagccac tccgacccca tagccaaagc ctcagaaatc
    13441 ccctctcctt gtgtagctga gtattcaaaa tctgggaaat ggacaaaata agtcgcttct
    13501 gttccgtctg tgtcgtcata ataaaataaa gctggatacg taactaacat ttcactacct
    13561 ccatatcaaa aagcagggac tgaattttac aacccagctt gctttcctat ccctctttca
    13621 gtgtacttat tcagctcacc atgaaggatt gtgataggtc tttccccttg cttctcgatt
    13681 ttaatatggg agcctttacc gcctctagtc tttatccaac catgggccgt aaagagttta
    13741 accatctctt tttgtgtcat aggcatagcg cttttacctc ctgacaacac cattataaca
    13801 cgtgttacac gtattgtaaa ggagtgatac ttattattct attatacata aaagccccta
    13861 gatgtggttc taagggaaac caatttattc agacctattt ttctaatgag tagtaaaaac
    13921 tgcttcttta tcgagcaatt catcatctgt atagtcaatt gtaaaagtat ctcgatctaa
    13981 gacagattga ggcggagttg aatgaatcat aggaccactg cgtactctat attttttatc
    14041 tccaattttt acaaactgat actcttcgaa aatcaaattc aaaccacgtc aacgtcgcct
    14101 taccgtactc aagtacagcc tgcggctagt ttcctagttt gctctttgat tttcattgag
    14161 tatgattaac tctcaagtct tcgaaatcag gattttcaac agttattaca aggaggcgat
    14221 ttactacttc aaaaacatca attattctat ttttcatatt ttttcaaccc attattagaa
    14281 tgaacttctt ggtaagcaaa atcaagttta gatttaatgt tttcgtacaa atctaaaatc
    14341 tcttttggag tatcttcccg gaagaaaagt tttcttttcc ctgaaataac ttgatcacta
    14401 agaatccaat gacgaatttg ttttgtaaaa at
//
LOCUS       DAVBCA010000053        14234 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.053, whole genome shotgun sequence.
ACCESSION   DAVBCA010000053 DAVBCA010000000
VERSION     DAVBCA010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14234)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14234)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14234
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.053"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(159..1085)
                     /locus_tag="VQU19_001632"
     CDS             complement(159..1085)
                     /locus_tag="VQU19_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2480855.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
     gene            complement(1078..1770)
                     /gene="ftsE"
                     /locus_tag="VQU19_001633"
     CDS             complement(1078..1770)
                     /gene="ftsE"
                     /locus_tag="VQU19_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HET2480856.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            complement(1788..2883)
                     /gene="prfB"
                     /locus_tag="VQU19_001634"
     CDS             complement(join(1788..2810,2812..2883))
                     /gene="prfB"
                     /locus_tag="VQU19_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HET2480857.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQDKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            complement(2991..3647)
                     /locus_tag="VQU19_001635"
     CDS             complement(2991..3647)
                     /locus_tag="VQU19_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET2480858.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKIGILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDESIDLPALREKFEANGIQVEEIARTSAKVL
                     "
     gene            complement(4112..4822)
                     /locus_tag="VQU19_001636"
     CDS             complement(4112..4822)
                     /locus_tag="VQU19_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2480859.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKIPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            complement(4822..5586)
                     /locus_tag="VQU19_001637"
     CDS             complement(4822..5586)
                     /locus_tag="VQU19_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2480860.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            complement(5586..6542)
                     /locus_tag="VQU19_001638"
     CDS             complement(5586..6542)
                     /locus_tag="VQU19_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HET2480861.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKLPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            complement(6546..7415)
                     /locus_tag="VQU19_001639"
     CDS             complement(6546..7415)
                     /locus_tag="VQU19_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HET2480862.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            complement(7683..8843)
                     /locus_tag="VQU19_001640"
     CDS             complement(7683..8843)
                     /locus_tag="VQU19_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET2480863.1"
                     /translation="MKKKFALSFVALASVALLAACVEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTNMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKDNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            complement(8944..9192)
                     /locus_tag="VQU19_001641"
     CDS             complement(8944..9192)
                     /locus_tag="VQU19_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HET2480864.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            complement(9271..9861)
                     /gene="clpP"
                     /locus_tag="VQU19_001642"
     CDS             complement(9271..9861)
                     /gene="clpP"
                     /locus_tag="VQU19_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HET2480865.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            complement(10035..10664)
                     /gene="upp"
                     /locus_tag="VQU19_001643"
     CDS             complement(10035..10664)
                     /gene="upp"
                     /locus_tag="VQU19_001643"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HET2480866.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETFQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(10753..11220)
                     /locus_tag="VQU19_001644"
     CDS             complement(10753..11220)
                     /locus_tag="VQU19_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HET2480867.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            complement(11239..11796)
                     /locus_tag="VQU19_001645"
     CDS             complement(11239..11796)
                     /locus_tag="VQU19_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HET2480868.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            11921..12766
                     /locus_tag="VQU19_001646"
     CDS             11921..12766
                     /locus_tag="VQU19_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET2480869.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEDGGLLM
                     GYEID"
     gene            12825..13997
                     /locus_tag="VQU19_001647"
     CDS             12825..13997
                     /locus_tag="VQU19_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HET2480870.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDDQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSNPI"
     gene            14048..>14234
                     /locus_tag="VQU19_001648"
     CDS             14048..>14234
                     /locus_tag="VQU19_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HET2480871.1"
                     /translation="MEHIILLRGVTPNGKNAIPKMSYLVDILTEADFQQVRTYIQSGN
                     IILESNLALEEIREQVHT"
BASE COUNT         4230 a         3092 c         2607 g         4305 t
ORIGIN      
        1 aatttctagt gcgccaaatt tcaagttcaa attagccatc aagaagtctt ctctggggga
       61 cttctttgga agctcttttc ttctacgcat ctcttttcaa aaactcttgt agcaaaaaag
      121 gagattttac aatctcctca taaaagcagc tattttacct aaatcttcaa gaatcggcgc
      181 atggatattc ctgatcccaa tgaaccaatg aaaaccccaa tcacaaatag tagggcaatc
      241 atcaacggac taaataaatc tggactaatc atggatagat tttgccctac caacgatttg
      301 ttgacagatt ggtaaacaat ttgataaaca ataaagacca aaacagatgg tgcgatagct
      361 cccaataaac cgataaaggc tccttctaac aagaacggtc cacggatata actgttttta
      421 gctccaacca agcgcatgat ttgaatttcg cgactgcggg aaataatggt aatacgaatg
      481 gtatttgaaa tcaagaaaac tgcgataaaa attaacaaag cagcaatccc tagtccccaa
      541 acacggataa atgaagctaa cttgaagagt ctttctgtat tggcaccgcc atcttgaacc
      601 tcagagacac cttcaatttt tttagcatct tcggctatag tttttacatc atttggagtg
      661 tttgcctcta caatataggc atcatagaga ggattggcat ctccttcaaa gattttccag
      721 ttatctccca ttatctcggt taatttttca tattgttctt ctttacttga aaaggtaaca
      781 cttttaaccg tagacatgtt cttcaaagaa tcatatacct tgtggtagtc attatttgta
      841 acagtttgac cttctttttc aattgtctga ctattatctt ccacatcctt tcggatataa
      901 actactacac ggacattatt ttcaatatct gtagctagtt tcgctgtatt gaaaataaca
      961 gatgcaaata ttgccaccaa ggtcaaagta atcatgactg aactgacagc agctactgtc
     1021 atccaaccat ttcgtttcaa actttttaag gcttcaaata aatggcgaaa aaatctacta
     1081 atcatcgtat ccatactctc cttttgattc gtcacgaacg acacggccat tttcaatggc
     1141 aatgacacgg tggcgcaagg tatttacaat ctggctatta tgagtcgcca tcaaaatagt
     1201 tgtcccttgt aggttaatcc gttccaagag attcataatt tcccatgaat tatccggatc
     1261 cagatttcct gttggctcat cagctatcaa tactttggga ttatttacaa ttgcacgcgc
     1321 aatcgcaatt cgctgctgct ccccacctga gagttcattt gggaaagaac gaaccttatg
     1381 cttcaatcca accaagtcca aaacttccat cactcgtctt ttgatattac ggcgattttc
     1441 cccgattact tccatagcgt aagcaatatt ttcatagaca gttttctttg gtaacaattt
     1501 ataatcttgg aagacaaccc caacactacg acgtagaagc gggacatctt tctttttgat
     1561 cttaaccaga ttaaaaccag caactgatag acttccttta tcgattttta cttcacgata
     1621 cagagaacga ataaaagttg acttccctgc tcctgaaggt cctacgatgt aagcaaattc
     1681 ccccggttga acgctgaccg aaacaccgcg tagagcagtc gttccgttgt cgtatttttt
     1741 aacgacatct ctcatttcaa taattgacat gtgagttcct ttctatctta gctaattcgc
     1801 cacttgagat aagcatctat aaaaccatct aggtccccat ccataacctt atctacctga
     1861 gcaacctcaa agctagttcg gtgatctttt accatagtat aaggcgtgaa gacataagaa
     1921 cggatttggc ttccccaagt gatctccttt ttctcacctt tgagagaatc tacctccgca
     1981 gccttcttat cttgctccat ttgatagagc ttagcctgca acatcttcat ggcacgatct
     2041 ctatttccat actgggtacg atccactgtt gattggacaa caattccagt tggaatgtgg
     2101 gttaaacgta cacctgttga aaccttattg acgttttgtc caccggcacc acctgaacgg
     2161 aaggtatcca tcttgatatc atcttcacgg atttccactt caatagtatc atccaattct
     2221 ggcatcactt ctacagatgt gaaagaggta tggcgacgtt tggcagagtc aaatggtgag
     2281 attcgcacta agcggtgaac acccatttct gacttgagga gaccataggc attaggccct
     2341 tcaaatgata aagttaccga cttaatacca gcctcatcac ctgcttggta atccaacact
     2401 tccactttaa agcctttagc attaccataa cgagtataca tacgaagcaa catatcaccc
     2461 cagtcctgcg cctcagtacc accagaacct ggatggattt ccaagatggc attgttgtgg
     2521 tcataaggtt ctgacaagag tagagtcatc tcgtagctgg tcattatctt atcaagttcg
     2581 gctaactgcg ctaccagttc atcatgcact gactcgtctt cagccaaaaa atccaataaa
     2641 atttcgactt catcctgcaa ctcttccatc ttatggaagg tattgtaagt gttttttaat
     2701 tcattcaatt cttgcgacgt tttttgggcc gcaatattat cgttccaaaa atcaggttct
     2761 gtcatcttgt tttccaagat ggcaatctct tcctctagcc cttcgaggtc aaagagaccc
     2821 cctgaaagaa gctaattttt cacgatttgc gtcaattttc tgacgaatta ctgaaatgtc
     2881 cataaatact ccttttttac attatttcat tatagcatat tttatcattt ctttccatct
     2941 tttgctctaa tccccttttc atgaaaaaag aagcctttgg acttcccttc ttacaagact
     3001 tttgctgaag tgcgagcgat ttcttccact tgaataccat ttgcttcaaa tttttctctc
     3061 aaggctggta aatcaattga ttcatcgatt tgcacttcga taatcacctt accatcctta
     3121 cgcggaatat tgactgtatg ggagatattc aaattttctt ctacaatcaa agaaacaatt
     3181 tttccaagaa caccaacttc atcttctgta acaaagcgta cacgaatccc ttcttcgcca
     3241 taacctgcaa tttcaagaaa ggcttggaaa acgtcacggt cagtaataac tccgtatact
     3301 tgatggttat ctacgacagg gagaatacca atcttatttt tcaacatcag ataagttgca
     3361 tcttctagac tagcatagcc tgagacagtg acaacatcgc gaatcatgac atcttttact
     3421 tttgtcttat tcagaagata attcatctca tagatagaaa gacttgttgc tttagatgga
     3481 cttgcttgtg caatggttcc ctcagtcacc aaaccaacca attgatcatt ttcgataaca
     3541 ggcagacggt gcaaaccttg ctctctcatc aaatctgctg catgagatac tgttgtatct
     3601 ggactaatat aaactacctt gcgggtcata aaatctttaa ctgccatgag acttctcctt
     3661 ttctattctt atccctatta tacaatcttt ttgcaaatct atcaaacgct tacatttctt
     3721 tttcaaaatt tagaaaagta tgaataagct agcaaaaaga gctctaaaat cgagctctgt
     3781 gaatgaaggt aagaaacttt tcattcgatt ttttcaatta ttagaaatta agctttcaat
     3841 gtagatgcag atttgtttgc aatctcaatc taccggctaa aacaatcctc tggatttgat
     3901 gattgcttcg caatcttcat ccaccgacta aaaagggccc ccggactata ttgatgatta
     3961 cttcgtaatc tttatctgcc ggctaaaaca atcctctgga tttgatgatt gcttcgcaat
     4021 ctcaatctac cgactaaaaa gggcccccgg actatattga tgattacttc gtaatcttca
     4081 tctgccgact aaaacaatcc actggattgt tttagccacc tagatatgct tttctgactt
     4141 cttctgatga agcgagttct tttcctgttc ctgataggac gatttttcct gtttccaata
     4201 catatcctcg gtcagagatt gcaagtgctt tattggcatt ttgttcaatc aagaggacgg
     4261 ttgttccttg cttctgaata tcttgaatga tatcaaaaat ctcttggatg aagattgggg
     4321 caagtcccat tgatggttca tctaaaagaa gaagttttgg tgttgacata agagcgcgtc
     4381 ccatggcaag catttgttgt tcccctcctg aaagagtagc tgcatcttgg ttcttacgtt
     4441 cttcaagacg aggaaagcgt gagaaaacct tcttcaagtt agcttgattt tcttcacgat
     4501 ttttctttaa gaaagctccc atttcaagat tttccataac agtcaagcca ggaaagacgt
     4561 ggcgtccttc tggaacttgt gaaagaccac ctgccacgat tttctgagct ggtatttttt
     4621 ggatttcttg acctaaaaat tcaatctttc ctgaacttgg tcgaaccaaa cctgacaagg
     4681 tgcgaagaat agttgtctta cctgcaccgt tggcaccgat aagggaaaca acttctcctt
     4741 cattaacttc aaagcttaca tcacggactg cttggatcat accgtaatgc acagaaagat
     4801 tttcaacttt taacatagac attaggcttc acctcctaga taagcttcga taacgcgttt
     4861 attggtctta atttcgtctg gagttccttg agcaattaaa cggccatatt caagtacgta
     4921 gatacgttct gttacttcca tgaccagatt catatcgtgt tcaatcaaca tgattgtaat
     4981 cttaaattca tctttgatac gacgaattaa ctcagtcaat tcggctgttt cctgtgggtt
     5041 catacctgct gctggttcat ctaagaagag aattttaggt tccgtagcaa gggcacgaac
     5101 aatttccaaa cgacgttgtt gtccgtagga aagattttta gcaagagtct ctgcatcacc
     5161 atctaaatca aagattttca acaattccaa agctttagcc tttaattctt tttcactctt
     5221 gtaaaaagct ggtaagcgta agaaactagt aaaaacatgc tgtttgtgat ggtttccaaa
     5281 agcaatcaaa acattatcta aaactgttaa atctttaaag agacggatat tttggaaagt
     5341 acgtccaagt cccaaagagg caatcttata aggtgatttc ccattcaaaa ggtgaccatc
     5401 tagggttact gttccctcgc ttggttcata aacaccggtc aaaaggttga aaagggtggt
     5461 tttcccagct ccgtttggac cgattaatcc aaccagttcc ccttcgttca attcaagagt
     5521 cacatctcca acagctgtta gaccaccaaa atgtttggtt aactgtttta cttcaagtaa
     5581 tgccattagt tttgttcctc cttcttagat tttttaaaga aacgtgatag gctcagttcc
     5641 cacgttccaa ggagtccacc tggtctgaaa atcattacca ataccaaggc taaagcgtaa
     5701 ataatcatac gcacactagc aacatcttgg agaagcatat tcaaaattcc cagaacaata
     5761 gccgaaacaa tcgcacctgt aatggaaccg agtccaccaa atacaacaat aatcaaaacg
     5821 ttgattgagt taatgaaggt gtaatctttc ggtacaacag acccgataaa tcctgcctga
     5881 agtgacccag caatacttgc agtaatggca ccaaagacaa aagcgatgat tttaatttta
     5941 gtcgtattaa ccccaactga ctcagcagcg atttcatctt cacgaacaga gagggttgaa
     6001 cggccaattg ggctacgcaa gaagttcaag gttgcaatgg ttgtaatcac gacaaagaag
     6061 taaaccattt gccaagttgt aaagttagga atccctaaga tacctgccgc accatttgta
     6121 agacttccac cattgatgat aaagatacgg ataatttcag aaacacctag agttgctacc
     6181 gcaagatagt cccccttcaa gcgcaaggtt ggaatgccga caagtaaggc aactgctcct
     6241 gaaagcaaag cccctacaag catagctcca aagaaggcac cgtaggttgg taatttagaa
     6301 ccaataatag ctgctgcata ggcaccaatc gccatgaaac cagcatgacc aagtgaaaat
     6361 tgtcctgaaa aaccaacgat taagttgaga ccaacagcca aaataatatt aattccaatt
     6421 tgttgtaaaa tctgtacata gaatagatta agtactccga ctgaaaccag tacactaatc
     6481 aagctatagc cagctaacaa aaggagtaac catagaatat taacttttaa attttccttc
     6541 atcgtttaca ccttctcttt cacattctta ccaaggatac cagctgggcg gacaatcaag
     6601 atcaacaaca agattccata aacaatggca tcacggaaat ctgacatccc aaaggcagtc
     6661 gcaaaggttt ccaatagacc aatcacaaag ccaccaagag ccgcaccagg aataattccg
     6721 ataccaccaa gtactgcggc aacgaaagat ttaagacctg gagtaacccc catcaaaggc
     6781 tcaagagagt tataataaag agcaatcaga acaccagccg cacccgcaag agcagaaccc
     6841 aaagcgaagg taaagctaat cgtacggttt acattgatcc ccatcaattg cgccgcgtcg
     6901 ctatctactg atactgcacg catggctttc cccatcttag tcttttggac aatgacttgt
     6961 aacaaaatca tcaaaatcaa ggaaatggcc aaaatcatta actgcacatt tgttaagcta
     7021 attggtccca aatcatatcg aactgtttga atcgcttgag ggaaggcacg ggtattggca
     7081 ccaaccagat agaccattcc atactccaat aggaaagaaa ccccaatagc cgtaatcaaa
     7141 acagcaatac gagtagagtg gcgcaaaggt cggtaagcaa gaaactcaat cacgacacca
     7201 agaatagctg tcgctagcat agctacaata agcgctacaa agaaattcat ttggaaagaa
     7261 ttgatcaaga aataaccgat aaaggctccc atcatataaa tatcaccatg ggcgaagttg
     7321 atgagcttga taattccgta aaccatggta tatcctaggg ctaacagcgc gtaaacacta
     7381 cctagaatca aaccatttac gagttgttgg agcataagat tcactctttc tatttataat
     7441 tccgagggtt ttccctcact ttttgatagg ttcttatact caatgaaaat caaagagcaa
     7501 actaggaaac tagccgcagg ttgctcaaag cactgctttg aggttgtaga taagactgac
     7561 gaagtcagtc acatatataa tccaaggcga cgttgacgca gtttgaagag attttcgaag
     7621 agtattaaat atcgaaacag ggagtgagtc aaaggctcat tccctatttc aacatttttc
     7681 tattatggtt ttacaacttc tgctgcttca actttaccat tgttcatggt catcatgtaa
     7741 gcagttttga ctgtgttgtg gtctgcatcg aagcttgttt gaccagttac accttcaaaa
     7801 tcttttgttt tagcaaggtt atccttgatt tcacctgaat ttttagcacc ttttgctgcg
     7861 tttgctacaa ggtgaactga atcataagcc aaggctgcaa atgttgaagg ctcttcattg
     7921 tacttagcac ggtaagcgtc aaggaaggct ttagctttag ctgaaacttc tacagtagtt
     7981 gagaagcctg agataaagta gatgtttgat gctttttcag cagttgcttg ttgtacaaac
     8041 tcctcaccgt tgaatccatc accaccaacg attggtttgt caattcccat gccacgcgct
     8101 tggtttacaa tcttaccagc ctcattatag taaccaggaa caacgatagc atcaaagtct
     8161 ttccctttca tgtttgtaag ggctgcttgg aagtctgtgt cacctgctac gaaagtttca
     8221 tctgcaacga tttcaccctt gtatgactcg cggaaagatt tagcaatccc tttagcatag
     8281 tcactggcat tgtcagtgta aagaacaact ttcttagcat ttaatttttc agaaacatag
     8341 tttgagataa tttttccttg gaagctatct tggaaagttc caataaagag gtaatcttga
     8401 cctttagtca atccatcttg agtcgcactt ggtgagatca atggaacacc tgcttttgta
     8461 gcgttcgcta ccgcagctgc agtcgcacca gatgtcgcag gtcctacgac tgctgatact
     8521 ttagattggg ttacaaggtt agttgtaact gaagcagcct cagctgtttc agacttatta
     8581 tctttatcga ctacttcgat ttgttttcca tcgataccac ctgcggcatt gatttcatca
     8641 acagccaatt gggcaccttt ttgttcagct gttccgtatg cagctaaaga acctgattct
     8701 tcaaagttaa acccgatttt aattgtcttt tcctctactg agttaccagc agtgttgact
     8761 gctccagact tcacttctac acaggctgca agaagtgcta cacttgcaag cgccacaaac
     8821 gatagggcaa attttttctt catctttttg tctccttatt tcttaaatag tctgttaaga
     8881 atataccgaa ttatcagaaa attgtcaatg ttttccttga actttttcga tgataacgtt
     8941 ttcctatcga taaagattgc ccacaaaggg tgtttccaac tcttggatat gacaaaccct
     9001 aactttttta ataaattttt ccttgctcaa gcgtccgacc aattgctcca cttcttgagt
     9061 tggaacatag agttgtaagt aacgatgttt cttggaatga taggtaatat ctccataatc
     9121 ctgcagtttt ttggcatcac gattatagta aagatagata atcaagccag agcgattgac
     9181 tttttcaaac atgataaatc ctctttctaa gaaatctctc cctattatac caaaaaaagc
     9241 aaacccagtc gagtttgcct tctatcatca ttagttcaat gaattgttgg ccataatttc
     9301 atcaataaag ccatattcaa gtgtttcctg ggcgctcatc cagttatcac gttctgcatc
     9361 tgcatggact ttttccattg actgacctga attttcagcc aagatttttt ccaaggtatt
     9421 acgagttttg agcaagtgtt ctgcagcgat agccatatca gtttgttggg taccaccacc
     9481 tgtaccgccc attggttggt gaatcatgta ttcagcattt ggaagcatga aacgtttgcc
     9541 ttttgctcca cttgatgcga tgactgttcc catagatgca gccattccca taacaatggt
     9601 ttggacatct gccttgataa agttcatggt atctacgatt gccaaaccag ctgaaacaga
     9661 accacctggt gtattgacat aaaggtaaat atcttttgta ctatcttggg catccaagaa
     9721 aagcagttgg gcaataacag agttagccat attgtcttca accggacctg tcagcataat
     9781 gatgcggtct ttgagaagac gtgagtaaat atcgtaagaa cgttctccac ggcttgtttg
     9841 ttcaataact acaggaatca ttcatttctc cttttgagtt ttaattttgt tggtcaaatg
     9901 actgaagata agactattat aatatcttgg tcaaaaaagg tcaaattttt gctctgcttt
     9961 cattagacag aaacaaaaac ccaacctcct ttcgtgactg gaaatacttt tccaagtcat
    10021 tcttcttttc gatcttattt tgtaccgaac aagcggtctc cagcatctcc aagacctgga
    10081 acgatataac cgtgttcgtt caaacgttca tccaaggctg ctgtaaagat ttctacatct
    10141 ggatgagctt cttgaagggc ttttacaccc tctggagcag atacaaggca gacaaatttg
    10201 atatttgatg cgccacgttt tttaagagaa tcaacagcca agattgctga gccacctgtt
    10261 gccaacattg ggtctactac aaaaatttga cgttggtcaa tgtcctcagg caatttcacc
    10321 aagtattcaa ctggttgaaa tgtttcttca tcacggtaca taccgatgtg gccaacttta
    10381 gcagctggaa ccaagctcaa gagaccatca accatcccga tacctgcacg caagattggg
    10441 acgatggcca atttcttacc tgccaattgt ttttgaactg tttttgtaat tggtgtttcg
    10501 atttccacat cttctagtgg aagatcacga agtacttcat accccatcaa cattgcaatc
    10561 tcatctacta gctcacgaaa agcttttgta gaagtatctg tacgacgcaa gattgacaat
    10621 ttgtgttgaa tcagtgggtg attaataact tcaatttttc ccatttttgg aattccttct
    10681 ttcaatttat tcttcttatt ataccaaaaa acgggttaaa aatctttcta aaccatttat
    10741 ttttgataat ttttacatta gatcagcctc tttaagagct gtctgtactg tctcaagtgg
    10801 taaatgggtc aattctgtcc ctttttcttg ataaaggtat tgggcgtagt cgtccattcg
    10861 gtactggttg atataaacca cacgcttgca gccgacctga agcaattgtt ttgtacagtt
    10921 gagacaagga aaatgggtta cataggctgt aaagcctttg ggaacaccac gctcagcacc
    10981 ttgaaggata gcattgacct cagcgtgaag ggtgcgaaca cagtggcctt caatgaccaa
    11041 acattcgtga tcaatacaat gctcagtccc tgacaccgaa ccattgtaac cagtggaaat
    11101 aaccttatta tcttttacca gaatcgcgcc cactttagca cgtttacaag tggaacgatt
    11161 cgcaattagt agagcttggg ctgcaaaata ctcatcccag gccagtcttt tttcagtcat
    11221 ctcttttctc ctttttctct attttttaaa aaatggtaaa cctaaatctg caatcttttc
    11281 agctggtacc ttcatgccat ccttgatcca ttttagaagg acagagacga tggctgagct
    11341 ccagaaggaa tgaagataag agctgacacc ttttgatttc ccatggtatt tttctagaaa
    11401 ttcctgcatg gcttggacaa agattttttc cagatggtaa tccaaggcca attgaattac
    11461 tctagcttcc tttctggcct cccggaaaag gtgaacccaa accaaataaa ggtctgtctt
    11521 taaatcgtaa tgatgcagct gttccataat attgtggaca gttcgtttaa agacgctctc
    11581 taaaatttcc tctttggagt cataattgcg ataaaaggcc gcacgcgaaa cacctgcacg
    11641 tttgaccaat tcagaaatac taatcttggt cagttccttt ttttccaaga gttgcaagag
    11701 ggctgtttca atggcttctc tggttaataa attggattct tggtttgatt ttctgagatt
    11761 ttcaagagac ttttcagaga ttctacgttc agacataaca ttttctttct acttgtcaca
    11821 acagacggat gatgcttttg tttcaagggt tttcatgata taattgtaaa aaaagacaga
    11881 acctttgtca atgtataact gacaaagatg gagaatttct atgacttgga agattattgc
    11941 tgactctggt tgtgattatc gtcaactgcc aacaccagct attaacacaa cctttgtaag
    12001 tgtcccctta accattcaag tagctgatca ggtctttgtt gatgacgcca gtctcgatat
    12061 tgaccaaatg atggaaacca tgtatgcaac tgcagaagct tcaaaatcgg cttgtccaag
    12121 cccagatgac tatttgcgag catttgaagg tgccaaaaac attttcctag taaccatcac
    12181 aggtaccctt tctggcagtc acaatagtgc tcaactagca aagaatattt atctggaaga
    12241 ccatcctgac actaagattc atgtgattga tagtttatct gctggtggtg aagttgacct
    12301 actcgtagaa aaattgaatg acttgattga ccagggcttg tcttttgaag aagtggttga
    12361 agctatcacc gcctatcaag aaaaaactaa gttgctcttt gtcctagcca aagtcgataa
    12421 cttggtgaag aacggccgtt tgagcaagct tatcggtacg gtcgttggcc ttctcaacat
    12481 tcgtatggtc ggaaaagcta gtgaaactgg aactctcgaa ttgctacaaa aagcaagggg
    12541 atcaaagaaa tcagttcaag ctgcctatga tgagttagta aaagctggat atgctggtgg
    12601 ccgtattgtc atggcccaac gcaataacga aaaatgttgt caacagctct cagagcgaat
    12661 ccgtgaaacc ttcccacaag cggatattaa aattctacca acctctggtc tctgcagttt
    12721 ctatgcagaa gatggcggtt tgctgatggg ctatgaaatt gattaattgt attcttgaca
    12781 agaggtgacc atcatctctt gtttttttgt ggtacaatag agctatgaaa cattttgata
    12841 ctattgtcat cggtggggga cctgctggta tgatggctac gatttccagt agcttttatg
    12901 gacagaaaac cctcctcatc gaaaaaaatc ggaaacttgg aaaaaaatta gctgggactg
    12961 gtgggggacg ttgcaatgtg accaacaatg gtagcttaga caacctgcta gctggaattc
    13021 ctggaaacgg acgctttctt tacagtgttt tctcccagtt cgataatcat gacatcatca
    13081 acttttttac agaaaatggt gttaaactta aggtcgaaga ccacggacgc gtctttccag
    13141 ccagtgacaa gtctcggact attatcgaag ctttggaaaa gaaaatcacc gaactaggtg
    13201 gtcaagttgc tactcaaata gaaatcgttt ctgttaaaaa agtagatgac cagtttgtcc
    13261 ttaagtcagc ggatcaaacc ttcacttgtg agaaactcat tgtcacaaca ggtggtaagt
    13321 cttatccttc gactggttcg actggttttg gtcacgagat tgctcgccat tttaagcata
    13381 ccatcaccga tcttgaggct gctgaaagtc ctttattaac agattttcca cataaagcct
    13441 tacaagggat ttctttggac gatgtgaccc taagttatgg taagcatgtc atcactcatg
    13501 atttactctt tacccacttt ggtttgtcag gtcctgctgc cctacgcatg tctagctttg
    13561 tcaaaggtgg ggaggttctc tcactcgatg ttttgcctca actttctgag aaggacttgg
    13621 ttacatttct agaagaaaat cgggaaaaat ccttgaaaaa cgctttaaaa accttgttac
    13681 cagaacgctt ggccgaattt tttgtacaag gatatcctga aaaagtcaaa caactgactg
    13741 aaaaggaacg agaacaactt gtccagtcca ttaaagaact taaaattcct gtaactggaa
    13801 aaatgtccct tgcaaagtcc tttgttacca agggtggagt cagtctcaag gaaatcaatc
    13861 ctaaaaccct tgaaagtaag ctggtacctg gcctccactt tgcaggcgaa gttatggata
    13921 tcaatgccca cacaggtggc tttaacatca cttctgccct ctgtaccggc tgggtggcgg
    13981 gatcaaatcc aatctaaata tacattacta aatggaacaa tcccccaaaa aaaagaaagg
    14041 aactactttg gaacatatta tcttgctaag gggagtcact cctaatggaa aaaatgctat
    14101 ccctaaaatg tcttatctag tagatatctt gacagaagct gattttcaac aagttcgaac
    14161 ttatattcaa agtggaaata ttattcttga aagtaactta gctctcgaag aaatacgaga
    14221 acaggttcat actc
//
LOCUS       DAVBCA010000054        12573 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.054, whole genome shotgun sequence.
ACCESSION   DAVBCA010000054 DAVBCA010000000
VERSION     DAVBCA010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12573)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12573)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12573
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.054"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(251..433)
                     /locus_tag="VQU19_001649"
     CDS             complement(251..433)
                     /locus_tag="VQU19_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480872.1"
                     /translation="MAVIFKNVLIEEKTEEEKQHILSILNGEYDLSDDVSCRLRRLNE
                     ESKRLEVFVKETNSLV"
     gene            complement(649..1881)
                     /locus_tag="VQU19_001650"
     CDS             complement(649..1881)
                     /locus_tag="VQU19_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HET2480873.1"
                     /translation="MKIAVAGTGYVGLSIAILLAQHHQVVAVDIIPEKVELINKKKSP
                     IQDDYIEKYLAEKELNLVATLNAEEAYENADFIVIAAPTNYDPKKNFFDTSSVEAVIE
                     AVMKYNPDAIIIIKSTVPVGYTKSVRRKFLTDNIMFSPEFLRESKALYDNLYPSRIII
                     GTDKDDKDLVKSAEIFVKMLQEGAVKENIETLYMDFTEAEAVKLFANTYLALRVSYFN
                     ELDTYSEMKGLDTQAIIDGVCLDPRIGSHYNNPSFGYGGYCLPKDTKQLLANYSDVPQ
                     EMITAIVQSNRTRKDYIADRILDLAGSYVGNDFYKPDKEKEIVVGIYRLTMKSNSDNF
                     RQSSIQGIMKRLKAKGVTIIIYEPTLESGTTFYGSQVVNDFEIFKKSSQVIVANRFDE
                     TLEDVRGKVYTRDIFKRD"
     gene            complement(1910..2980)
                     /gene="gla"
                     /locus_tag="VQU19_001651"
     CDS             complement(1910..2980)
                     /gene="gla"
                     /locus_tag="VQU19_001651"
                     /EC_number="5.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001214397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucuronate 4-epimerase Gla"
                     /protein_id="HET2480874.1"
                     /translation="MRGKTILITGVAGFIGSNLVRKLLELEGTMTIIGLDNLNDYYDI
                     ALKDYRLLQLNKLIQDYPEKNWIFIKGDIADKMLINKIFKSYHPQIVVNLAAQAGVRY
                     SITNPDVYIESNIVGFHNVLEACRHSYEIYDGGVEHLVYASSSSVYGGNKKIPFATED
                     KVDNPISLYAATKKTNELQAYAYSKIYNIPSTGLRFFTVYGPAGRPDMAYFGFTDKLR
                     SGSDIEIYNHGNCKRDFTYIDDIVEGIVRVMQSAPKKLVGSDNLPLAPYKVYNIGNSK
                     PENLLDFVDVLQQELIKAGVLPENYDFDSHKKLVPMQPGDVPVTYADTSDLERDFGFK
                     PKTSLREGLRKFAEWYKDYYNV"
     gene            complement(3048..4217)
                     /locus_tag="VQU19_001652"
     CDS             complement(3048..4217)
                     /locus_tag="VQU19_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HET2480875.1"
                     /translation="MRLSKKYWFALTSKFLLILLTLLSSIIINRGLGVEKKGDYAYVM
                     NLVEIFYILGGVGLGQAYSTFKRNHSNEYQNKFVFLTFIQGLLFGIIGLIIVLADVPI
                     DYGGVIIVLSSLSIMRTNLTMIAVIENSIKRNKIVLGVSVVYSVMLVLLLLFHLVSIE
                     MVFLVYAINEFLRIILFLYYYNMFPVFEHISIKEFFTIYKFGFLSMILTLLITFNYSI
                     DIIMLKQMSSSYNVGIYSVAVTFSNMFLMVPDSFKEILFGDSAKRTFEKNKAINAIKV
                     SFLFMILLIIGFLSFGEFAITLLYGSSYIKAFPITLVIFLGSLSMIFFKILQPIYISQ
                     GKQSVAIKILSVSALINISLNWYLIPNYQITGAAIASAISYTVCGLFFIIDYLRN"
     gene            complement(4403..5707)
                     /locus_tag="VQU19_001653"
     CDS             complement(4403..5707)
                     /locus_tag="VQU19_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide repeat unit polymerase"
                     /protein_id="HET2480876.1"
                     /translation="MKFSLQSNDIKNKIILLVGVVFSGTLILCSENNDVTIPLFSMIF
                     LSFMAMIIVKFNIFHPYVWYSSFFTIYSISYPLLYRMEYINYGYTKDLIFMQWLALAT
                     LLLTLPSKAIVLSERKINLNNNNYLLFLNNMNTFITTVAIIYLLGSGFRNKGEIYSGA
                     NIVIMLVFSLVYFMILIHTYQLFIQLSTKKWRLLNCNTNTAIVICLFSIVTGERDYMF
                     TLFILDVIILFYFHKIKRFYLVMLVPLAALLIPLSAVFKYTLLSGQVSSINTNNIWFD
                     LLDGEFVSASRNLQILILHNMGNYFEGRSFFNDIVRIFYNTGYSNQTWFMDTFFPNVH
                     STKYGFTLVGEGYVNGGYFGIVMIFMLTGFLMRFLYINAQRNIYGMLIYLYMIPIFIY
                     STRADFANILSPLLKYAILGTLVIVFINRMVLISPLDEMGGE"
     gene            complement(5824..6978)
                     /locus_tag="VQU19_001654"
     CDS             complement(5824..6978)
                     /locus_tag="VQU19_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET2480877.1"
                     /translation="MKVFIATEFRCTIYKNEIYLKPKAYFIYERYAKAFGEIVLCSRY
                     EKVESYPEGYHKANFINKFIPIEGLHQVLFGQNKNKIIEGMIDSDLIVVRIPSIIGSK
                     TADYALKIGKPYLTEIMGDAWDSYWYHSLKGKLLAPYIYAKTKSIVKNANYCIYVTEK
                     YLQDRYPNIKSNIVASNVNITSVENRSLKSRLYKLKKFNPQKISIMTTASVNVRAKGH
                     RFVLEAMKRLEIQGILLDYYLAGDGDQSFLKKKAEELGVANRIHFLGELTTSQIYEYL
                     DKVDLYIQPSLQEGLPRAVIEAMSRACPCIGSNKAGIPELLGPHCLFTPSSSQAIAGS
                     IIDFISMDKEKMVIKQFEFSKKFLSSVLNKRRSDYFAQIRRELNNSDGLD"
     gene            complement(6975..7526)
                     /locus_tag="VQU19_001655"
     CDS             complement(6975..7526)
                     /locus_tag="VQU19_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HET2480878.1"
                     /translation="MNRIIKNIVGLLRANICLILLKVCRNKDLTFHYFLKFGKNVTVE
                     QESNAKLILGKKIRVNAGGVLKVRKGAKLKISDDVFLSNNCMIACRKYIDIKSGVKCG
                     PGVLIYDHDYDVSVPGGLKAKKFKTAPVMIGENVWIGANSIVLKGVSIGENSVVAAGS
                     VVTKDIPADTIFIQKRLSREMKL"
     gene            complement(7519..8655)
                     /locus_tag="VQU19_001656"
     CDS             complement(7519..8655)
                     /locus_tag="VQU19_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001053205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET2480879.1"
                     /translation="MNLQKKKIMLITNHDDDIYCFRKEVIESLVEYGYEVLVSCPYGD
                     KIELMKSIQFEYEDITIDRRGINPLKDIRLFLSYIRLLRKYRPDVVLTYTVKPNVYAS
                     LAATILGIKYINNVTGLGSVLTMGSCVRSLVLLLFRISFRKSNCVFFQNEYNMKMLKT
                     LGLILGDSKLIPGSGVNIEKYPVQQYPNGGNGIQGETIVFNFIGRILKEKGIDTYLAA
                     AQIIKSRYPKTEFNIIGFIEPTESNYELKICDLEKKGIVYYLGQQKDVIPHITRSHAI
                     IHPSVYGEGMSNVLLENASSGRVLITTDNPGCKEIVKDRETGYIFQGGNVEELVSILE
                     VFLGLENEKRKEMGLQGRMYIEQYFSRQIIIDAYLDKIKGALDE"
     gene            complement(8796..9461)
                     /gene="cpsD"
                     /locus_tag="VQU19_001657"
     CDS             complement(8796..9461)
                     /gene="cpsD"
                     /locus_tag="VQU19_001657"
                     /EC_number="2.7.10.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis tyrosine autokinase
                     CpsD"
                     /protein_id="HET2480880.1"
                     /translation="MPTLEIAQKKLEFIKKAEEYYNTLCTNIQLSGDKLKVISVTSVN
                     PGEGKTTTSVNIAMSFARAGYKTLLFDGDIRNSVMSGFFKSREKITGLTEFLSGTADL
                     SHGLCDTNIENLFVVQSGSVSPNPTALLQSKNFNDMIETLRKYFDYIIVDTPPIGIVI
                     DAAIITQKCDASILITATGEANKRDVQKAKQQLEQTGELFLGVVLNKLDISVDKYGVY
                     GRK"
     gene            complement(9471..10163)
                     /gene="cpsC"
                     /locus_tag="VQU19_001658"
     CDS             complement(9471..10163)
                     /gene="cpsC"
                     /locus_tag="VQU19_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CpsC"
                     /protein_id="HET2480881.1"
                     /translation="MKEQNTLEIDVLQLFRALWKRKLVILLVAIITSSVAFAYSTFVI
                     KPEFTSTTRIYLVNRNQGEKPGLTNQDLQAGAYLVKDYREIVLSQDVLEEVISDLKLD
                     LMPKGLANKIKVTVPVDTRIVSVSVSDRVPEEASRIANSLREVAAQKIISITRVSDVT
                     TLEEARPAISPSSPNIKRNTLIGFLAGVIGTSVIVLLLELLDTRVKRPEDIENALQMT
                     LLGVVPNLGKLK"
     gene            complement(10172..10903)
                     /locus_tag="VQU19_001659"
     CDS             complement(10172..10903)
                     /locus_tag="VQU19_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein phosphatase CpsB"
                     /protein_id="HET2480882.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAESYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVADDLVIAYGAEIYYTLDALEKLEKKEIPTLNDS
                     RYALIEFSMHTSYRQIHTGLSNILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QINSYHVSKPKFFGEKYKFMKKRARYFLERDLVHVVASDMHNLDSRPPYMQQAYDIIA
                     KKYGAKKAKELFVDNPRKIIMDQLI"
     gene            complement(10905..12350)
                     /locus_tag="VQU19_001660"
     CDS             complement(10905..12350)
                     /locus_tag="VQU19_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HET2480883.1"
                     /translation="MSRRFKKSRSQKVKRSVNIVLLTIYLLLICFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLLFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSKIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VNQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADS
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGVDVHNDQ
                     EFSALHGKFHFPVGNVHLDSEQALGFVRERYSLTDGDRDRGRNQQKVIVAIIQKLTST
                     EVLKNYSSILQGLQDSLQTNIPIETMIDLVNTQLESGGNYKVNSQDLKGTGRMDLPSY
                     AMPDSNLYVMEIDDSSLTVVKAAIQDVMEGR"
BASE COUNT         4237 a         2433 c         1656 g         4247 t
ORIGIN      
        1 aattcactta cttcatatta catttagcat gaaatgaaat aagcgaattc tactttgttt
       61 gcatacaatt aaaaatcaat tcctaaggat gttttaaata actgtgtaaa aggcataatt
      121 tcaccatttc ttagtttttc aatgctaaat tacatagtaa ctggagagct attagaaatc
      181 tctaacttcc tcatagttaa aaaatgacaa tgagatactt attgatttca attcattaac
      241 agaatacgaa ctagacaagt gagttcgtct ccttaacaaa cacttccaag cgtttacttt
      301 cctcattcag tcgtcgtaat ctacaactta catcatcaga taagtcatac tcaccattta
      361 gaatagatag aatatgttgt ttttcttctt cagtcttctc ttcaataagc acatttttaa
      421 aaattactgc cattatcagc acctcacttc gaaggaatat atgcaactat atcctattaa
      481 gtcaatctct actgacaaaa gaagtatatt tacttcacta agtgcgagcg agaatataga
      541 aatatcttta ttgttttaga tgagttgtcg ctatcctcca gctagttttt aactattcta
      601 tcattcaaat gatatagatt attagggact agaaatatac aaattgattt aatctctctt
      661 aaaaatatcc ctagtataaa ctttacccct cacatcttct aaagtctcat caaaacgatt
      721 tgcaacaatc acttgactag atttcttaaa tatttcaaaa tcattaacta cttgactacc
      781 atagaaagta gtaccacttt caagagttgg ttcgtaaata ataatagtaa caccttttgc
      841 tttcaaacgc ttcataatac cttgaataga agattgtcta aaattatctg aattactttt
      901 cattgttaaa cgataaattc ctacaacaat ctctttttct ttatctggtt tatagaaatc
      961 attgcctaca taagatccag caagatctaa aatacgatct gcaatataat cttttcttgt
     1021 ccgattactt tgtactatag ctgttatcat ttcttgtgga acgtcagaat aatttgcaag
     1081 aagttgcttg gtatctttag gaagacagta acccccataa ccaaaagaag gattattgta
     1141 gtgagaacct attctcggat ctaaacaaac tccatcaata atcgcttgag tatctagtcc
     1201 tttcatctca gaataagtat ctaactcgtt aaaataggaa acccggaggg caagataggt
     1261 attagcaaaa agttttactg cttcagcttc tgtaaaatcc atatacaatg tttcaatatt
     1321 ttctttcact gcaccttcct gaagcatttt tacaaaaatt tcagcagact ttaccaaatc
     1381 tttatcatct ttatctgtac ctataataat tcgactcgga tataggttat catataacgc
     1441 ttttgactcc cgtaaaaact caggactaaa cataatattg tctgtaagaa atttcctccg
     1501 tactgacttt gtatatccaa caggaacagt acttttaatt attataattg catcaggatt
     1561 atatttcata actgcttcaa tgacagcctc gactgaagat gtatcgaaaa aatttttttt
     1621 cggatcataa ttagttggag ccgcaataac tataaaatcc gcattctcat atgcttcctc
     1681 tgcattcaat gtagctacga gattcaattc tttttccgcg agatattttt ctatataatc
     1741 gtcttggata ggggacttct ttttattgat taactcaact ttctcaggaa tgatatctac
     1801 ggcaacaact tgatgatgtt gagccagtaa gattgcaata gataatccaa catatcctgt
     1861 acctgctact gctattttca taattttttc ctttctcaaa acactctcgt tatacattat
     1921 agtagtcttt ataccactct gcaaactttc tcaaaccttc tcgtaaagaa gtttttggtt
     1981 taaaaccaaa atctctctct aaatcacttg tatctgcata agtaacagga acatcgcctg
     2041 gttgcatagg aactaatttt ttatgactat caaaatcata attttccggc aaaactcctg
     2101 ccttgattag ctcctgttga agaacatcca caaaatctaa caaattttcg ggtttactat
     2161 tcccaatatt gtacacttta tatggggcta acggtaaatt atcagatccc actagtttct
     2221 tcggagctga ttgcatgacc cttactatcc cctcaacgat atcatctata taagtaaaat
     2281 ctcgtttaca attaccatga ttataaatct caatatcgga accacttcgc aatttatctg
     2341 taaatccaaa ataggccata tctgggcgcc cagcaggacc ataaactgta aaaaagcgta
     2401 agcctgtcga aggaatattg taaatctttg aataagcata cgcttgaagt tcatttgttt
     2461 ttttagtcgc agcatatagt gaaataggat tgtctacctt atcttctgtt gcaaacggga
     2521 tttttttatt tccaccatat accgatgagg acgatgcata aactaagtgt tccacaccac
     2581 catcatatat ctcatacgaa tgacgacaag cttccaacac attatgaaag ccaacgatat
     2641 tactttctat atatacatct ggatttgtaa tggagtagcg tactcctgcc tgggcagcta
     2701 gattaacaac aatctgagga tgataactct taaaaatctt attaataagc attttatctg
     2761 caatatcacc cttgataaat atccagtttt tttctggata atcctgaatt agcttattaa
     2821 gttgaagcaa tcgataatct ttaagtgcaa tatcatagta atcattcaaa ttgtccaaac
     2881 caatgattgt catcgttcct tctaattcca ataatttcct aaccagattt gatccaataa
     2941 aaccagctac tcctgtaatt agaattgttt ttcctctcat atcataatac ctcttgttat
     3001 ttttatattt tcgtccacta atacacattc tttaacaact attataatca atttctaaga
     3061 taatctataa taaaaaacaa accacataca gtataagaga ttgctgatgc tatcgcagct
     3121 cctgtaattt ggtagttagg aattaagtac cagtttaaac ttatatttat caaagccgac
     3181 acagataaaa tttttatagc tacactctgt ttaccctgag atatataaat tggttgtaaa
     3241 attttaaaga aaatcatcga taagcttcct aaaaaaatga ctaatgttat aggaaatgcc
     3301 tttatataac tggaaccata aaggagcgta atcgcaaatt ctccaaaaga aagaaatcca
     3361 ataattaata aaatcataaa tagaaatgat acttttattg catttattgc tttatttttc
     3421 tcaaaagttc ttttagccga atcaccaaat aaaatctctt taaatgagtc tggaaccatc
     3481 aaaaacatat tagaaaacgt aactgcgaca ctgtatatac ctacattata actactagac
     3541 atttgcttca acattatgat atcaatacta taattaaatg taattaatag agtaagaatc
     3601 atagaaagaa atccaaactt atatatagtg aaaaattctt taatactaat atgttcaaaa
     3661 actgggaaca tattgtaata gtataaaaat aaaatgatac gtaaaaattc attaatagca
     3721 tataccaaaa ataccatctc tatagaaact aaatgaaata gtaacaacaa tactagcata
     3781 acggaatata ctacgcttac tcctaataca atcttattcc tctttatact attttctatt
     3841 actgcaatca tagtaagatt tgttctcata atagatagac tggacaaaac tattattacc
     3901 ccaccataat ctatcggaac atcagctaaa actattatta aacctattat tccaaacaat
     3961 aatccttgaa taaaagttaa aaaaacaaat ttattctgat actcattaga atgattcctt
     4021 ttaaaggtcg agtaagcctg acctaaacca actccaccta aaatataaaa aatttctact
     4081 aagttcatta cataggcata atctcctttt ttttcaacac ctaatcccct attaattata
     4141 attgaggata aaagtgttaa taagattaac aaaaatttac tcgttaaagc aaaccaatat
     4201 ttcttagata gtctcactta ttttctccgt atgttaaatt ttataacagt aaatttaaaa
     4261 ttatagtata ttgaaataga atatgaacaa aacgattagg gaatttaaag taatttataa
     4321 aaattcttta gaagctgcat tgtactactc caacttcaaa ccactatagt atcaaaaagt
     4381 ataccccacc tttttaaata aactactcac cacccatttc atccaatggt gatatcaaca
     4441 ccattctatt gataaaaaca ataaccaatg ttcccaatat agcatattta agtaatggag
     4501 ataatatgtt agcaaaatca gcacgagtag aataaataaa aataggtatc atatacagat
     4561 atatcagcat cccgtatata tttctttgag cgtttatata aagaaatctc atcaaaaagc
     4621 ctgttagcat aaaaatcatt acaattccaa agtatcctcc attcacatat ccctctccca
     4681 caagagtaaa accatatttg gttgaatgta cgtttggaaa aaaggtgtcc ataaaccaag
     4741 tttgattaga ataccccgta ttataaaaaa ttcttactat gtcattaaaa aaagaacgac
     4801 cttcgaaata attgcccata ttatgtaata tcagaatctg taaattacga ctagctgata
     4861 caaactcacc atctagcaaa tcaaaccaaa tattatttgt atttatagat gaaacttgcc
     4921 cacttaataa agtatattta aaaactgcag ataacggaat cagtagtgcc gcaagcggaa
     4981 ctaacattac aagataaaaa cgttttattt tgtgaaagta aaataatata atcacatcaa
     5041 ggatgaataa agtaaacata taatctcttt cccctgtaac gatagagaag agacagataa
     5101 ctatcgctgt gttagtatta caatttagta gtctccattt tttagtactc aactgtataa
     5161 atagctgata tgtatgaatg agaatcataa aataaaccaa agaaaatact aacattatca
     5221 caatattggc acctgaatat atttcccctt tatttctaaa accacttcct aatagatata
     5281 taattgctac tgttgtgata aacgtattca tattattgag aaataataaa tagttattgt
     5341 tatttaggtt tattttcctt tcgcttaaca caatggcttt agaaggtaga gttaacaaca
     5401 aagttgccaa agccagccat tgcatgaaaa tcaaatcttt tgtataacca tagtttatat
     5461 actccattct atagagtagc gggtaagaaa tagaataaat agtaaagaag ctactatacc
     5521 acacataggg atgaaaaata ttaaatttca caattatcat tgccataaaa cttaaaaaaa
     5581 tcattgaaaa taatggaatt gtaacatcat tattttcact gcataaaatt aaagtccctg
     5641 aaaaaactac acctactaga agtattattt tattttttat atcatttgat tgtagactaa
     5701 acttcattta cttttttcct ttaactaata atttaaacgt aatgcgtatt caaaaatttg
     5761 attggctatg tagtcagttt ttatagcata tttaatatat cgaaacggat tttccatcgc
     5821 attttaatct aaaccatcag aattatttaa ttctcttcta atttgagcaa aatagtcact
     5881 tctgcgttta tttaatacac tcgaaagaaa tttttttgag aattcaaact gttttatcac
     5941 catcttttcc ttatccatac taataaaatc tataatagat cccgcaatcg cttgtgaaga
     6001 ggatggagta aatagacaat gtggccccag caactctgga attcctgctt tattagaccc
     6061 tatacaaggg caagcacggc tcatagcttc aattaccgca cgaggtaacc cttcttgtaa
     6121 acttggttgt atatataaat caactttatc caaatactca taaatttgtg atgtagtcaa
     6181 ttcccctaaa aaatggattc tattcgctac tcccaattcc tctgctttct tttttaagaa
     6241 actttgatca ccatcacctg ctaaataata atccaacaaa ataccttgta tttctaatct
     6301 cttcattgct tccaatacaa atctatggcc cttggctcgt acattcacag atgctgttgt
     6361 cattattgaa attttttgag gattaaattt tttcaactta taaagacggc tcttcaaaga
     6421 tctattctct acagaggtaa tattaacatt tgaagcaacg atattagatt taatattagg
     6481 atatctatct tgtaaatatt tttctgtcac gtatatgcaa taattagcgt tttttacaat
     6541 tgatttagtt ttggcgtata tatatggagc taataatttt ccctttaaac tatgatacca
     6601 gtaagaatcc caagcatccc ccattatttc tgtcagatac ggcttaccta tcttcaatgc
     6661 gtagtctgca gtttttgatc caattataga cggaatacga acaactatta agtcgctatc
     6721 aatcattcct tcaataatct tatttttatt ttgaccaaat agaacctgat gtagaccttc
     6781 tatagggata aatttattaa taaagttcgc tttatgatat ccttcagggt atgattccac
     6841 cttctcataa cgactacata gtacaatctc tccaaatgct ttagcatagc gctcataaat
     6901 aaaataagct ttcggtttta aatatatttc atttttatag attgtacatc taaattcagt
     6961 cgctataaat actttcataa tttcatctcc cttgataaac gtttctgaat aaatatagta
     7021 tcagctggaa tatcctttgt tacaacactt cctgctgcaa ccacactatt ctcaccaata
     7081 ctcactccct tcaagacaat gctgttagct ccaatccaaa cattttctcc aatcataact
     7141 ggggccgtct taaatttttt tgctttcaat ccacctggaa cactaacatc atagtcatga
     7201 tcatatataa gtactccagg accacatttt actccagatt taatatctat gtatttacga
     7261 caagctatca tacaattatt actcaaaaat acatcatcag aaatcttgag ttttgctcct
     7321 tttctaactt tcaatactcc cccggcgttt actctaatct tttttcctaa gattaattta
     7381 gcattagatt cctgttcgac agttacattc tttccaaatt ttaaaaaata atgaaaagta
     7441 agatccttgt ttcgacacac ttttaataat atcaagcaaa tatttgcacg aagtaaacca
     7501 acaatatttt ttataatcct attcatctaa agctcctttt attttatcta aataagcatc
     7561 tataataatt tgacgagaaa aatattgctc tatatacatt ctcccttgaa gtcccatctc
     7621 ttttcgtttt tcattttcta gacctaaaaa aacttccaat atagagacta gttcctcaac
     7681 atttccccct tgaaatatat agcctgtctc tctatcttta acaatttctt tgcaacctgg
     7741 attatctgtc gtaattaaaa cacgtcctga actagcgttt tctagtaata cattgctcat
     7801 tccttcacca tacacactgg gatggataat tgcatgggaa cgggtaatat gaggtatcac
     7861 atctttttgt tgtcccaaat aataaacgat tccttttttt tctaagtcac aaattttaag
     7921 ttcataatta ctctctgtcg gttctataaa gccaataata ttaaactctg ttttgggata
     7981 tcgactctta ataatttggg cagcagccag ataagtatct ataccttttt cttttaatat
     8041 cctaccaata aaattaaaaa cgattgtttc tccttgaatt ccatttccac catttggata
     8101 ctgttgcaca ggatactttt caatgttcac tcctgaccca ggtatcagct tagagtcacc
     8161 caaaatcaag ccaagagttt ttaacatttt catattatat tcattttgaa aaaaaacaca
     8221 atttgatttc ctaaaagaaa ttctaaacag taataacacc aggcttctta cacaagaacc
     8281 cattgttaag acactaccta aacctgttac gttatttata tattttattc ctaaaattgt
     8341 tgcagctagg ctagcatata catttggttt cacggtatat gtcaagacta catccggtct
     8401 atattttctc aataatctta tataactaag aaatagacga atatctttta aagggtttat
     8461 tcctcttcta tcaatagtaa tatcttcata ctcaaattga atagacttca tcaactctat
     8521 cttatctcca taaggacatg acactagcac ttcataccca tactcaacta gtgactctat
     8581 aacttctttt cgaaaacaat agatatcatc gtcatgatta gttattaaca taattttttt
     8641 cttttgtaaa ttcatcaaaa taatcttcct aaaatataat taaccgctac tccattatcc
     8701 tttacaacta tcattttaaa aatagtaatt ttctataagt aattgtttcc aaattgtgac
     8761 actttaaaat tctatacaca tatagaactt acaaactatt tacgaccgta aactccatac
     8821 ttatcaaccg agatatccaa tttatttaaa acaactccca ggaacagttc ccctgtttgt
     8881 tctaattgtt gtttcgcttt ttggacatca cgtttattcg cctcacctgt tgctgttatc
     8941 aagatggacg catcacactt ttgagtgata attgccgcat caataacaat tccaataggt
     9001 ggtgtatcaa caatgatata atcaaaatat ttacgcaatg tttcaatcat atcattaaaa
     9061 tttttacttt gtaacaaggc tgtagggttt ggtgatacag atcccgattg aactacaaat
     9121 aaattttcaa tatttgtatc acataaaccg tgagataaat cagctgtccc agataaaaat
     9181 tctgttagcc ctgtaatttt ttcacgagat ttaaaaaatc ctgacataac tgaatttcga
     9241 atatcgccat cgaacaaaag agttttatag cctgcacgcg caaatgacat tgctatattt
     9301 acggaagtag ttgtttttcc ttcccccgga ttaacagaag taacggaaat tacttttagt
     9361 ttatctccgc tcaactgtat atttgtacac aaggtattgt aatattcttc tgccttctta
     9421 atgaactcca gttttttttg tgctatttct aatgtcggca tctctctctc ctatttcaac
     9481 ttacccaagt ttggtacaac tcccaaaagt gtcatctgca gtgcattttc gatatcttcc
     9541 ggacgtttca cacgagtgtc caaaagttca agaagaagaa ctataacact agttccaatc
     9601 acccctgcca aaaaaccaat tagtgtattg cgtttaatat ttggcgaaga cggtgatatc
     9661 gccggtcttg cctcctccag tgttgtcaca tcagaaacac gagtaatact gataattttt
     9721 tgagcagcta cttctcttaa agagttagcg atacggcttg cctcttcagg aactcgatca
     9781 ctaactgaaa cagagacaat acgggtatca actggtactg ttactttaat tttattagcc
     9841 aaaccttttg gcatcaaatc tagtttcaaa tcagaaataa cttcctccaa aacatcctgc
     9901 gataggacaa tttcacgata gtctttaacc aagtatgctc ctgcctgcaa gtcttgattg
     9961 gttaaaccag gcttctctcc ctgattacgg ttaactagat aaatccgagt cgtactagta
    10021 aactcaggtt tgataacaaa agtactgtag gcaaaagcaa ctgaagaagt tataattgcc
    10081 actaataaaa tgaccaactt tcttttccat aaagctctga atagttgcaa tacatcgatt
    10141 tccaaagtgt tttgttcctt catattttct cctaaattaa ttgatccatt ataatttttc
    10201 tgggattatc tacaaaaagt tctttcgctt ttttcgctcc atatttctta gcaatgatat
    10261 catatgcctg ttgcatatat ggaggtctac tgtctaaatt gtgcatgtca cttgcaacta
    10321 catgaactaa atcacgttcc aaaaaatacc gagctctctt tttcatgaat ttatattttt
    10381 caccaaagaa cttaggtttt gaaacatgat aactatttat ctgagtatag caccccatat
    10441 caatcagttc acgaacacgt ttttcgttat tctctaaagc atcataacgt tcaatatgag
    10501 caattactgg cgtgattccc aacatcaaaa tattgctcaa tcccgtatga atctgacgat
    10561 aggaagtatg catgctaaac tcaatcaagg cataacgact atcattaagg gtaggaattt
    10621 cttttttttc tagcttttct agagcatcca gagtatagta tatctctgcg ccataagcaa
    10681 tgactaaatc atctgctact tcttttgcaa tttcccgaac ctgaagaaag ttttctgcta
    10741 tcttctcttc cggagtttca aacatgccct tgcgacggtg agaggtagag acaatggttc
    10801 tcaccccctg cctgtaggat tctgccaaga gagccttgct ttcctctctt gacttgggac
    10861 catcatctac atcaaagacg atgtgcgaat ggatgtctat cattttatct accctccatc
    10921 acatcctgta tagctgcttt aactacagtt aaactactat catctatttc catcacatag
    10981 aggttactgt ctggcattgc ataagaagga agatccatcc gacctgtccc ttttaaatct
    11041 tgagaattta ctttataatt ccctccactt tccaactgag tattcactaa atctatcata
    11101 gtctcaatcg gtatatttgt ttgaagagaa tcctgcaatc cttgaagaat actactatag
    11161 tttttcaaaa cctctgtaga agttaacttc tgaataattg ctacaatgac cttttgttgg
    11221 ttgcgaccac ggtcacggtc tccatcggtt agtgagtagc gttcacgtac aaaacctaaa
    11281 gcttgctcag agtctagatg gacattccct actgggaaat ggaacttccc atgtagagct
    11341 gaaaactctt gatcattatg aacatctacc cctcccaata agtcaatcat tttcaagaaa
    11401 gaagtgaagt tcaatcgcac atagtaattg atatccactc catagagatt ttctaaggtg
    11461 tgaatggacg aatcaactcc ataaatgccc gcatgggtta atttatcttt ttgattattt
    11521 ccactatctg cgattggtac ataggcatca cgtggcgttg tggtcaagag gattttcttg
    11581 gtatctcgat tgacagtcat taggatattg acatctgatc gcgacaccga actaatagga
    11641 ccataggtgt caattccact aacatagata ttgaaagact gattcttaga cgtcttagga
    11701 gcctctactt ttttagtgaa tcccttggta taaatctttt ttatcttcga tgcgtagtct
    11761 ggatactctg actcgatgat attttcaaag acactattta ggacaatggc cttagtctcc
    11821 cctgcaatca aactcttgta agctgccaag taagacgaac tctggttgac cgtcaaatcg
    11881 gtattctgac ttgacttgat atcagctagt agtttttgaa tattttcatt atcagtccca
    11941 gtcggtgctg tcacactcgt cagttgcgta acattttcga tcttactatc tgctaaaaca
    12001 gcgacactga ttgaatattc tgagtaatta gaagtcgcat ttaaacgatt ggtcagtcca
    12061 acaaactgct gtactgcaaa gagcgacact gagctgacaa ggatagagaa cagcaacaga
    12121 aaaatagtaa acttttcagc ttttttatag ataatcaaga gtagccctac caaggcaact
    12181 agtaggacta acgcagttac cactaggtta agatatctaa aagcaaggat attgtactta
    12241 aagattaaga acaataaaaa acaaattaac aataaataaa tagtcagcaa aacgatatta
    12301 acacttcgct tcactttctg tgaacgtgat tttttaaaac gtctactcat gattaacacc
    12361 tataccttga acatcataca attatatcac ttttttacgg taatgtctac acctttattt
    12421 tcactatctg catctttaag tatcttagta gacttcccgc gaaccaaaaa tatagtaaaa
    12481 tgaaataaga ataggacaaa tcaatcagga cagtcaaatc gatttctaac aatgttttag
    12541 aatcagatgt gtactattct agtttcaata taa
//
LOCUS       DAVBCA010000055        12493 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.055, whole genome shotgun sequence.
ACCESSION   DAVBCA010000055 DAVBCA010000000
VERSION     DAVBCA010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12493
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.055"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            311..571
                     /locus_tag="VQU19_001661"
     CDS             311..571
                     /locus_tag="VQU19_001661"
                     /inference="COORDINATES: protein motif:HMM:NF012235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2480884.1"
                     /translation="MSGGETKRVALAKIILKNPPLIFADELTASLDSTTSQGIMKLLL
                     GMKNKNRLIIIATHNPDIWNQADEVINLNQLLQSIYIFYILK"
     gene            complement(675..1145)
                     /locus_tag="VQU19_001662"
     CDS             complement(675..1145)
                     /locus_tag="VQU19_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET2480885.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQTLLAENDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(1162..3435)
                     /locus_tag="VQU19_001663"
     CDS             complement(1162..3435)
                     /locus_tag="VQU19_001663"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HET2480886.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLASDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
     gene            3782..6883
                     /locus_tag="VQU19_001664"
     CDS             3782..6883
                     /locus_tag="VQU19_001664"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HET2480887.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQGVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQERFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     ETEGIHLKIEEIDLEDKETLALFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDPVLEDILAPTYGIMLYQEQVMQVAQRLAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSLEAGHTVEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQVMLNSSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKAIYLGLKSIKGVSNDLALWIIENRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEVREGAFYYIKGKVQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSDELEAKLNEIVMKT
                     IYR"
     gene            6965..7972
                     /gene="pfkA"
                     /locus_tag="VQU19_001665"
     CDS             6965..7972
                     /gene="pfkA"
                     /locus_tag="VQU19_001665"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HET2480888.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            8029..9534
                     /gene="pyk"
                     /locus_tag="VQU19_001666"
     CDS             8029..9534
                     /gene="pyk"
                     /locus_tag="VQU19_001666"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HET2480889.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(10266..10491)
                     /locus_tag="VQU19_001667"
                     /pseudo
     CDS             complement(10266..10491)
                     /locus_tag="VQU19_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            11339..12211
                     /locus_tag="VQU19_001668"
     CDS             11339..12211
                     /locus_tag="VQU19_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HET2480890.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            12224..12388
                     /locus_tag="VQU19_001669"
     CDS             12224..12388
                     /locus_tag="VQU19_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001836122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480891.1"
                     /translation="MTVILGFLFLFLMTWWVISIVNSQKPRKNETFIGYIQRYDIDGN
                     GYQSLPCPQN"
     gene            complement(12357..12493)
                     /locus_tag="VQU19_001670"
                     /pseudo
     CDS             complement(12357..12493)
                     /locus_tag="VQU19_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
BASE COUNT         3811 a         2175 c         2667 g         3840 t
ORIGIN      
        1 tctttctaat gagttgtttt gtcgcttttc attataggtc atatgggact ttttttctac
       61 aataaaatag gctccataat atctatagtg gatttaccca ctacaaatat tatagaaccc
      121 ttttttattg acagtatcag gatatctttt tcaaattttt ggtttgttag ataatgaaaa
      181 tgtttctatc aatctagatt taggattaat aaatcgtaaa tgtaattata aagaaaaaga
      241 taagttaaaa aaagatgtat tagcaagagt tggtctaact catattcatc tataacaaaa
      301 gatatatgaa ttgtctggcg gtgaaacaaa acgtgttgct ttagcgaaaa tcattcttaa
      361 aaatccacca ttaatattcg cggatgagtt gactgcatca ctcgattcga cgacttcaca
      421 aggaattatg aaattgttat taggtatgaa aaataaaaat cgtctaatca tcattgcaac
      481 tcataatccc gatatttgga atcaagcaga tgaagttata aatttaaatc aattattaca
      541 gtcaatatat atcttctata ttttaaagta attttatctg aatccgttaa gagactattg
      601 tcccaggctc tttctgatgt taaagacttt ctaccaggtt ttttaaaagc ataattgtta
      661 gttgtagtca tttattattc ttcaaagaaa aatggtgggg cgaatttttt cagttcttca
      721 aagcactttt gagcagtatc tgcatcttca cagatgataa gacagacatc attaccacaa
      781 agggtagcga tagcgtcagg gaagctcaaa gtatcaatga tagaaccaaa ggattgagcc
      841 agtccaggaa gggtttttag taggacttgg tgttgaactg ggcgcatcca gacaagggcg
      901 tcttccatgt agagttcgag acgtttttcc cattttgaga tggaaccatt gttaagaaca
      961 taataagcgc tatcttcttc gcggactttt gataggttca tatttttgat gtcgcgtgag
     1021 agggttgcct gagttacttg aatgtcgttc tcagcaagaa gggtttgcaa ctcagcctgt
     1081 gtatgaatct tgttttttgt gataagagcg cgtataagtt ggtggcggtg ttctgattta
     1141 ttcataataa tgtaactcct tttagcaagg taaggtaagc atggactgag cgaggtcgac
     1201 agtcaagtgg tagtctgtat tgtcacggat ggtgatttca aagtcagtag tatagaggac
     1261 taaacggaga gtgtctcctt cttttagctt gtaaatagtt ggctgcagtt caaattgaac
     1321 gtccatccat tcatctgcag taatatcctc tactaacagt aaatcatttc tattttgtaa
     1381 attaaggtaa ccttttgtca cgactctttg tgcctctggt ctaaatggca attcacagag
     1441 attttccaac atgtgatagc gaccgttgtc aatggttcta gcacttaaaa tagctggata
     1501 aggttgtagg tatttctttt gcccaaattc tagcagttgg gcagataaga gccccttgtt
     1561 tgtactggat ttgatacgaa gattgagctg agcgcgaccg tttaggtgga gatctttagt
     1621 cacaggaagg ttaatagtaa tctgattagc tttcccttga tagagctctg tattgaaggt
     1681 ttggtatgtc ttaccatagc gctcaaaatc cttatctggg tactggtttt gaatagcttg
     1741 ctcttcttga ccaagtgaga aggtttcaca gttttcttgc ccaccgaagt tatcaagtga
     1801 taaccaagtc tgtggagctg tattgtcctg ccagataaca gtaggaagtt gaaagtctgt
     1861 ttcctgtcct agtaatttct tggtcaataa ggcatttatg gactcacgga agtcaattga
     1921 ttgccaattg ttcatgtaaa catgggcacc attatggaaa aagagatgct tgtgtatatg
     1981 agtaggaaga gcatggaaca tctggtaaac atgaagtggt ttgacattcc aatcctgaga
     2041 accatgagta aagacaacct ctgcctttac tttatgggca ttgagcagat aattgcggtc
     2101 atgccaaaac tgattgtagt ccccagtttt tcggtctagt tgagctttca ctttttctaa
     2161 gtcagcttgg tgagcttcat tgccacggat atagtcgcta gccaagagat tacgagaata
     2221 ggttaactca gcaagggagt caaagtcctc acctggataa ccacctgggc tagtcaccag
     2281 accgttttca cggtagtagt tgtaccatga tgaaattcct gcctcggcaa tgataacttc
     2341 taaaccatcg actcctgtag tcgcaagacc attggacatg gtacctagat aggaaagtcc
     2401 cgttgtagca acttttccgt ttgaccaatc agccttgact tgacgctggc gcgtgtgatc
     2461 agtaaaggca cggcaacggc cgttaagcca atcgatgaca tttttataag cctcgatttg
     2521 ctggtagtct ccattagtca tgaaacctgt cgagtctttg gtaccaacac ctgagacata
     2581 gagattggca aagcctctcg gaaggaagta gtcgtttagt gtatagctag agttgatgtg
     2641 agttagcttt tcctcagcct ctgctataag ctcagcttta ccttggggtt ggacgagatt
     2701 tagttgaggt ttctctagct caatcttgtg aggaagttta acctcaagct cgccctccat
     2761 cttgtagaga gccttgtcac tagccttgtc attggttccc tgatgataag ggctggctgt
     2821 catgatggca gggatttttc catcaaaacg agggcgaata atgctaacct ttactaggtc
     2881 tgatagccct ttttggtcag tatcgacacg agactcaacg taaacgactt cacgaatgac
     2941 atcctggtta gaaaaagtag ccaaactctt gccgttaaag tagtggtagt cattatcctc
     3001 cggaataaga ccatcactaa caagttggtc gataagagta tttccttttt tggtgcgagt
     3061 attgagtaac tgatagagat tttcaatcaa gtcaccatat ataatgggaa atccagtttc
     3121 tttacgaaaa acgtcactat cttcgaagtc aaccaaataa gaaaagccta aaagttgaaa
     3181 agcaacagta taaaaaatat ctgctgtcag ttcatcttct gattgaaaaa atgtcagcag
     3241 gtctgttttt ttatcagctg ctaggataga aagtgggtag ttggtgtctt gataagtgaa
     3301 aaagaaacga cgtaaaaagg tttcaagtga gtctttgtga ttggctgtat tttgtaaatc
     3361 aaagccacat ttttttagtt cagataagac attttctttt ggaaaattga tataactata
     3421 ttgattaaaa cgcatagaac ctccatatag aatgacagtt aaggttatta tatcaaaaaa
     3481 aaagcagaaa gggaattgtt aacttcaaaa ggaaataatc caataaaaat gaataaagta
     3541 ctaaattcaa tatagagaac agagtaacaa taagaataaa tagatagggt ataaaagttc
     3601 taggagattt atattatatg ctttctgttt ttatatacaa tatagtataa atataaaaat
     3661 gatgacaaaa atacaaatga atagaaaata aattagtaag ctgatgaaat ttttctcaag
     3721 agaagccatt tataggtgaa aatggtataa tatagtgaga aggatagagg agaagtgtaa
     3781 attgatcgca caactagata caaaaacagt ctatagtttt atggaaagcg tcatttcgat
     3841 cgaaaagtat gtgagagcag ctaaagaata cggctacact catttggcta tgatggatat
     3901 tgacaatctt tatggcgctt tcgactttct agagattaca aaaaaatacg gcattcatcc
     3961 tttgctaggg cttgaaatga cagtgtttgt agatgatcag ggagtgaatt tgcgcttttt
     4021 agctctatct agtgtgggct atcagcagtt gatgaagctt tcgacagcca agatgcaggg
     4081 ggagaaaact tggtcagtcc tgtcccagta cctggaggat atcgcggtca ttgtgcctta
     4141 ttttgataga gttgagtcgt tagaactagg ctgtgattac tatatagggg tttatccaga
     4201 aacactagca agcgaatttc atcatcctat cttacctctt tatcgggtca acgcttttga
     4261 aagcagggat agagaagttc ttcaagtttt aacagcgatt aaagaaaatc taccgctcag
     4321 agaagttccc ttgcgttcga gacaagatgt ctttatatca gcaagttctt tagagaaact
     4381 attccaagag cgttttccgc aagctttgga caatttagaa aagcttattt caggcatttc
     4441 ttacgacttg gatactagtc tgaaactgcc tcgttttaat ccagctagac cagcagtaga
     4501 ggagttgaga gagcgtgctg aactggggct tgttcagaag gggttgacta gtaaagaata
     4561 tcaagataga ctagaccaag aattgtctgt tattcatgat atgggctttg atgattattt
     4621 cttggttgtt tgggatttgt tgcgttttgg acgatcgaat ggctattata tgggaatggg
     4681 aaggggttct gcagtaggca gtttggtttc ttatgcctta gacatcacgg ggattgaccc
     4741 agtagagaaa aatctgattt ttgaacgctt tcttaatcgt gaacgctata ccatgcctga
     4801 tattgatatt gatatcccag atatttatcg tccagatttt atcagatatg ttggtaataa
     4861 atatggtagt aaacatgcgg cacaaatcgt tactttttca acctttggag ccaagcaagc
     4921 tcttcgagat gtcttgaaac gctttggtgt gccagagtat gaattatctg caattactaa
     4981 gaaaatcagt tttcgtgaca atcttaagtc ggcctatgag ggcaatctcc agtttcgtca
     5041 gcaaatcaat agtaagttag aataccaaaa agcttttgag attgcttgca agatagaggg
     5101 ctatccaagg caaacctctg tccatgcggc tggtgttgta attagtgacc aagatttaac
     5161 caactacatt cctctaaagt atggtgatga aattccactg actcagtatg atgctcatgg
     5221 agttgaggct agcggacttt tgaagatgga ctttctggga ctacgaaatt tgacctttgt
     5281 ccagaagatg caagagttgc ttgctgaaac agaaggtatt catctgaaaa ttgaagaaat
     5341 cgatttagaa gacaaagaaa cattagcttt atttgcctct ggtaatacaa aaggtatctt
     5401 tcaatttgag caaccaggtg ccattcgtct gcttaagcgt gtgcaaccag tctgttttga
     5461 agatgtcgtc gcgactactt ctctaaatcg accgggtgct agtgactata tcaataattt
     5521 tgtggcaaga aagcatgggc aggaagaagt gactgttctg gatccagtac tggaggatat
     5581 tttggctcca acctacggca taatgctcta tcaggagcag gttatgcagg ttgcccagcg
     5641 acttgccgga tttagtcttg ggaaagccga tattttgcgt cgggctatgg ggaaaaagga
     5701 tgcctctgcc atgcatgaga tgagggcttc ctttattcaa ggttcattag aagctggtca
     5761 tactgtggaa aaagcagagc aggtctttga tgttatggag aagtttgcag gttatggttt
     5821 taacaggtca cacgcctatg cctactcagc cttggccttc cagttggctt atttcaaaac
     5881 gcattatcca gccatttttt atcaggtcat gttaaattct tccaacagtg attacttaat
     5941 agatgcactt gaagcaggtt ttgaagtagc ctctctatcc atcaacacca ttccctatca
     6001 cgataaaatt gccaacaagg ccatctatct aggtttgaaa tccattaaag gagtcagtaa
     6061 tgatttagct ctctggatta ttgaaaatag accttattct aacattgaag attttatagc
     6121 taaattacct gagaattatc tgaaacttcc tctgctagaa cctttggtaa aagttggtct
     6181 tttcgattca tttgaaaaaa atcgtcaaaa agtatttaat aacttagcta atctatttga
     6241 atttgtgaaa gagttgggaa gtttgtttgg agatgctatt tatagttggc aggaatcgga
     6301 agattggacg gaacaagaaa aattttatat ggaacaagag cttttaggga taggtgtcag
     6361 caaacatcca ctacaagcta ttgcaagtaa ggctatttac ccgattaccc caatcggaaa
     6421 tttgtcagaa aatagctatg ctattatctt ggttgaagtt cagaaaataa aagtgattcg
     6481 taccaaaaag ggtgaaaata tggccttctt acaggcagat gatagtaaga aaaaattgga
     6541 tgttacactc ttctcagatt tatatcgaca ggttggtcag gaagtaagag aaggagcatt
     6601 ctactatatc aaagggaaag tccaatcacg tgacggtcgt ctgcaaatga ttgcacaaga
     6661 aataagagaa gcagttgctg aacgcttttg gatacaggtg aaaaatcatg aatcggatca
     6721 agaaatttca cgtattttag aacaatttaa aggcccaatc ccagtcatca tccggtatga
     6781 agaggaacag aaaaccatcg tttctcccca tcattttgta gctaaatctg atgaattaga
     6841 ggcgaaattg aatgaaatcg ttatgaaaac gatttatcgc taaaaatacg gaaaatagaa
     6901 gaattttaaa atcaaatgtg atataatcaa gaagaatgtt aaaagaaaaa ggagcataac
     6961 caatatgaaa cgtattgctg ttttgactag tggtggagac gcccctggta tgaacgctgc
     7021 catccgtgca gttgttcgtc aagcaatttc agaaggaatg gaagtgtttg gtatctatga
     7081 cggatatgct ggtatggttg ccggtgaaat tcatccccta gatgcagctt cagtagggga
     7141 catcatttct cgtggtggta ctttccttca ctcagctcgt tacccagagt tcgctcaact
     7201 tgaagggcaa cttaaaggga ttgagcaatt gaaaaaacac ggaattgaag gtgtagttgt
     7261 tatcggtggt gacggatctt accacggcgc tatgcgtttg actgaacatg gcttcccagc
     7321 tattggtctt ccaggtacaa tcgataacga tatcgttggt actgacttta caatcggttt
     7381 tgacacagcg gttactactg ccatggacgc tatcgataag attcgtgata catcatcaag
     7441 tcaccgtcgt acttttgtaa tcgaagttat gggacgtaac gctggtgata tcgctctttg
     7501 ggctggtatt gcaactggtg ctgatgaaat catcatccct gaagcaggct tcaagatgga
     7561 agatatcgta gcaagcatca aagctggtta tgaatgtggt aaaaaacaca atatcatcgt
     7621 cttagctgaa ggtgtgatgt cagcggctga atttggtcaa aaacttaaag aagctggaga
     7681 tacaagcgac cttcgtgtaa cagaacttgg acatattcaa cgtggtggtt ctccaactgc
     7741 gcgtgaccgt gttttggcgt cacgtatggg tgcacatgct gttaaacttc ttaaagaagg
     7801 tatcggtggt gttgcggttg gtattcgtaa cgaaaaaatg gttgaaaatc caattcttgg
     7861 tactgcagaa gaaggggcat tgtttagcct tactgcagaa ggtaagattg tggttaacaa
     7921 cccgcacaaa gccgatattg agctatctag cttgaataag agcttgtcat aatttacaat
     7981 ttagttaata agaccaaaaa ggtcatatat aaaggagtca caaaaatcat gaacaaacgt
     8041 gtaaagatcg ttgcaacttt gggtcctgcg gtagaaatcc gtggtggtaa aaaattcggt
     8101 gaggacggat actggggtga aaaacttgat gttgaagctt cagctaaaaa cattgctaaa
     8161 ttgattgaag ctggtgctaa cacattccga ttcaacttct cacacggcga ccaccaagaa
     8221 caaggtgagc gtatggcaac tgttaaactt gcggaaaaaa ttgcaggtaa aaaagttggt
     8281 ttccttcttg atacaaaagg acctgaaatc cgtacagaat tgttcgaagg tgaagctaaa
     8341 gaatattcat acaaaactgg tgaaaaaatt cgtgttgcaa ctaaacaagg aatcaaatca
     8401 actcgtgaag tgattgcgtt gaacgttgct ggtgctcttg atatctatga tgatgttgaa
     8461 gttggtcgtc aagttttggt tgacgatggt aaacttggtc ttcgtgtggt tgctaaagat
     8521 gatgcaactc gtgaatttga agttgaagtt gaaaacgatg gtatcatcgc taaacaaaaa
     8581 ggtgtgaaca tccctaacac taaaattcct ttcccagctc ttgctgaacg cgataacgac
     8641 gatatccgtt tcggtcttga acaaggtatc aacttcatcg caatttcatt cgtacgtact
     8701 gcaaaagatg tgaacgaagt tcgtgcaatc tgtgaagaaa ctggaaacgg acatgttcaa
     8761 ttattcgcta aaatcgaaaa ccaacaaggt atcgataact tagacgaaat catcgaagca
     8821 gctgatggta ttatgattgc tcgtggtgat atgggtatcg aagtaccgtt cgaaatggtt
     8881 ccagtttatc aaaaaatgat tatcaagaaa gtcaatgctg caggtaaagt tgttatcact
     8941 gcaacaaaca tgcttgaaac aatgactgaa aaaccacgtg caactcgttc agaagtatca
     9001 gacgtattca acgctgttat cgacggaact gacgctacaa tgctgtcagg cgagtctgca
     9061 aacggtaaat acccactcga gtcagtaact acaatggcta caatcgacaa gaatgctcaa
     9121 gctcttctta atgaatacgg acgtcttgat tcagattcat ttgagcgtaa ctctaagaca
     9181 gaagtaatgg cttctgctgt taaagatgct actagctcaa tggatatcaa attggtcgta
     9241 actcttacta agacaggtca tactgcacgt ttgatttcta aataccgtcc aaatgctgac
     9301 atcttagcat tgacatttga cgaattgaca gaacgtggct tgatgttgaa ctggggtgtt
     9361 atcccaatgt tgacagatgc tccatcttca actgacgata tgttcgaaat cgctgaacgt
     9421 aaagcggtag aagcaggtct cgttgagtca ggcgatgata tcgttatcgt tgctggtgtg
     9481 ccagtaggag aagctgttcg cacaaacaca atgcgtatcc gcacagtacg ttaagaaaaa
     9541 tataaaaacc tatcatatcc agctttagag cttgtgtgat aggctttttg tatagagggt
     9601 aagaaatagg caaaactttc ataatggatt gatactcttc gaaaatcaaa ttcaaaccac
     9661 gtcagcgtcg ccttaccgta tatatgttac tgacttcgtc agttctatct acaacctcaa
     9721 agcagtgctt tgagcaacct gcggctagct tcctagtttg ctctttgatt ttcattgagt
     9781 atgaaataag atatgcacaa attgattagg aaattcaaat gaatttctac aaatgtttta
     9841 gcaatcgtaa tgtacttgtc tagattcgat ctgatatatt ttcgatttaa tgatatggta
     9901 tttaaaacct ccaaagtagc ttgctccatt cttttactta cgtgagtgta gatgttattt
     9961 actgttttag cgtttttgtg ttccactcta accattatag cattcttctc agctagtgta
    10021 ctaaggagtg tgtgcctgaa aatatgggaa ctaaggggct ggtttatcgg tttctctagt
    10081 ttagtatttg ccttttgcaa agtgatgtta aatgcctttc tctaaattta catatcacta
    10141 ttgtttaaca aaatctaatc tactttaggt cacttattct ttttttgaaa tgtagaatga
    10201 actttttcaa agtttttcga atcttttaaa atctgtttgt tttatatcgc cattctcccc
    10261 cttttttaat tctccctata tagcctgaca actttcccga tggtacgaat atggttgctt
    10321 tcgtctaggt ggatgtcggg gtatttggga ttgagttttt ttaaggtagc cttggcggag
    10381 tttcttgaca tagttagcgc cgtctacttg gaagatgccg atggtattat agtcaatctg
    10441 tggggtattc ttgataaata ggtagtcgct gtttcttatc tttggctcca tggacttgct
    10501 gacgacataa gcgattgggt cgtagtcgtc tgggataatg gaaactccat aactaaatcg
    10561 tcgtcctgca tcgagcggct acctgcagag ataaactacc taacacgaga gtaagtagtc
    10621 tgtctgtagt cgtccagtct gatgattttt acgatatttc gtttttctgc tcatacagtt
    10681 gcctctcggc ataggtcaga actttacctt gtctgggtgg tgcccgttgg tcgtagatag
    10741 attggatatc gctaggagaa tccttttgaa ctggaggaaa gagggtatca atcaagctac
    10801 tgaatacttt agctaagtca aatatagtat ttttcttagt agacctaacc cttttttcat
    10861 aatttccaat ggtgttttta cttataccaa tcttagtacc caattcttat tgagtccaac
    10921 cattactagt ctatattgtt ttatagttga ttgagtttgg aatagtacgc tgtagctgct
    10981 aaaacatttc taggaattaa tttgactttc ctaatagagt tgttcatatc ttatttcaat
    11041 ctactatgtt tttcacctct aacaatcgca atctcttctt tatccatgaa tgaaatcgct
    11101 ttctattttt gtaagtaaag catcacacga aatccacgaa aatgaaaacc tttgttgtgt
    11161 tttcgtaaaa aatttgttga cagagcacga aacgcctact ataattaaat caagcttaag
    11221 gaaataacaa aaaaacaaat cggagggaaa gacgatgaac acattaaatg agaaagtaat
    11281 caatatctgt aaagcagtag ttaaagaaac tttaatccaa gacatttagg agaaagaaat
    11341 gaagaaatca agaaaattag ccacattagg aatctgttca gccttgtttt taggcttggc
    11401 tgcttgtcaa caacaacatg ctacttctga ggggacgaat caaaggcaaa gcagttcagc
    11461 gaaagttcca tggaaagctt catacaccaa cctaaacaac caggtaagta cagaagaggt
    11521 caaatctctc ttatcagctc acttggatcc aaatagtgtt gatgcatttt ttaatctcgt
    11581 taatgactat aataccattg tcggctcaac tggcttatca ggagatttca cttcctttac
    11641 tcacaccgaa tacgatgttg agaaaatcag tcatctctgg aatcaaaaga agggcgattt
    11701 cgttgggacc aactgccgta tcaatagtta ttgtcttttg aaaaattcag tcaccattcc
    11761 aaagcttgaa aagaatgacc aattgctttt cctagataac gatgcgattg ataaaggaaa
    11821 ggtctttgat tcacaagata aggaagagtt tgatattcta ttttcgagag ttccaactga
    11881 ggcaactaca gatgtcaagg ttcacgctga aaagatggaa acattcttct cacaatttca
    11941 attcaatgaa aaagctcgaa tgctgtctgt agtcttgcac gacaatctgg atggcgagta
    12001 tctgtttgta ggccatgttg gggtcttagt acctgctgat gacggtttct tatttgtaga
    12061 gaaattgact ttcgaagagc cctaccaagc gattaaattt gctagtaagg aagattgcta
    12121 caagtatttg ggcaccaagt atgcggatta tacaggcgag ggactggcta agccttttat
    12181 catggataat gataagtggg ttaaacttta atagtgttat gatatgacag taatcttagg
    12241 atttttattt ctatttttga tgacttggtg ggttatttca atcgttaata gccagaaacc
    12301 acgcaaaaat gaaacattta ttggctatat ccaaagatac gatattgatg ggaatggcta
    12361 tcaatcatta ccgtgtcctc agaactgaga ggagttcttg aaaccgtaaa accgctttga
    12421 acaagagtta cttcaaccca ttggctccga cggagtaagt tgctttcgtg aataccaaaa
    12481 tcagccgcaa ttt
//
LOCUS       DAVBCA010000056        12327 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.056, whole genome shotgun sequence.
ACCESSION   DAVBCA010000056 DAVBCA010000000
VERSION     DAVBCA010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12327)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12327)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12327
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.056"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            270..2561
                     /gene="pcrA"
                     /locus_tag="VQU19_001671"
     CDS             270..2561
                     /gene="pcrA"
                     /locus_tag="VQU19_001671"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HET2480892.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTTYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKSASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            2604..3284
                     /gene="radC"
                     /locus_tag="VQU19_001672"
     CDS             2604..3284
                     /gene="radC"
                     /locus_tag="VQU19_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HET2480893.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(3281..3970)
                     /locus_tag="VQU19_001673"
     CDS             complement(3281..3970)
                     /locus_tag="VQU19_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HET2480894.1"
                     /translation="MKKPVIGITGNEKAHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYNLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(3988..4629)
                     /locus_tag="VQU19_001674"
     CDS             complement(3988..4629)
                     /locus_tag="VQU19_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HET2480895.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            complement(4712..4927)
                     /locus_tag="VQU19_001675"
     CDS             complement(4712..4927)
                     /locus_tag="VQU19_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HET2480896.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGQKVYQGLVGDLYRFLSHADFLHQN"
     gene            complement(4935..5282)
                     /locus_tag="VQU19_001676"
     CDS             complement(4935..5282)
                     /locus_tag="VQU19_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HET2480897.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFSLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            complement(5287..6402)
                     /locus_tag="VQU19_001677"
     CDS             complement(5287..6402)
                     /locus_tag="VQU19_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET2480898.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            complement(6412..7371)
                     /locus_tag="VQU19_001678"
     CDS             complement(6412..7371)
                     /locus_tag="VQU19_001678"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HET2480899.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            complement(7484..8053)
                     /locus_tag="VQU19_001679"
     CDS             complement(7484..8053)
                     /locus_tag="VQU19_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HET2480900.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAEDYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDITDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            8181..8852
                     /locus_tag="VQU19_001680"
     CDS             8181..8852
                     /locus_tag="VQU19_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HET2480901.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            8836..9654
                     /locus_tag="VQU19_001681"
     CDS             8836..9654
                     /locus_tag="VQU19_001681"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HET2480902.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            9651..10547
                     /locus_tag="VQU19_001682"
     CDS             9651..10547
                     /locus_tag="VQU19_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET2480903.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIDIPAEEGFETLEAIEHPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            10591..11565
                     /gene="pta"
                     /locus_tag="VQU19_001683"
     CDS             10591..11565
                     /gene="pta"
                     /locus_tag="VQU19_001683"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HET2480904.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
     gene            complement(11881..>12327)
                     /locus_tag="VQU19_001684"
     CDS             complement(11881..>12327)
                     /locus_tag="VQU19_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HET2480905.1"
                     /translation="LIQQDSRKLSDKRFYRPTFRMHLTNKEILDKLLSYSQDLKHHYQ
                     LYQLLLFHFQNKEPEKFFGLIEDNLKQVHPLFQTVFKTFLKDKEKIVNALQLPYSNAK
                     LEATNNLIKLIKRNAFGFRNFENFKKRIFTALNIKKERTKFVLSRA"
BASE COUNT         3587 a         2342 c         2657 g         3741 t
ORIGIN      
        1 tatcgaaatc atcgtaaacg cttcggatta cgaatgaatt tgattgctgg cattatcaat
       61 catgaactag gattctagtt ttgcaggaag tctattgagg tattgagcta gtttatgaaa
      121 aaattgggtg aaaaagtcga gtgttttaga aacccacagt gtagtattct agtttcaatc
      181 cactatattt tgctactccc cgtaaagttt ctattttccc tgatttctga tataatagaa
      241 atattgactt caagagtaag gaagagaaga tgaacgcatt attaaatgga atgaatgacc
      301 gtcaggctga ggcggtgcaa acgacagaag gtcccttgct aatcatggca ggagctggtt
      361 ctggaaagac tcgtgtttta acccaccgta tcgcttattt gattgatgaa aagctggtca
      421 atccttggaa tatcttggcc attaccttta ccaacaaggc tgcgcgtgag atgaaagagc
      481 gtgcttatag cctcaatcca gctactcagg actgtctgat tgcgaccttc cactccatgt
      541 gtgtgcgtat tttgcgtcgc gatgcggacc atattggcta caatcgtaat tttacaattg
      601 tggatcctgg tgaacagcga acgctcatga aacgtattct caaacagttg aacttggatc
      661 ctaaaaaatg gaatgaacga actattttgg ggaccatttc caatgctaag aatgatttga
      721 ttgatgatgt tgcttatgct gctcaagctg gcgatatgta tacgcaaatt gtggcccagt
      781 gttatacaac ctatcaaaaa gaacttcgtc agtctgaatc cgttgacttt gatgatttga
      841 ttatgctgac cttgcgtctc tttgatcaaa atcctgatgt tttgacctac taccagcaaa
      901 aattccaata catccacgtt gatgagtacc aagataccaa ccacgctcag taccaattgg
      961 tcaaactctt ggcttcccgt tttaaaaata tctgtgtggt tggggatgcg gaccagtcta
     1021 tctacggttg gcgtggtgct gatatgcaga atatcttgga ctttgaaaag gattacccca
     1081 aagctaaggt tgttttgttg gaggaaaatt accgctcaac caaaaccatt ctccaagcgg
     1141 ccaacgaggt tattaaaaat aataaaaatc gccgtcctaa aaatctctgg actcaaaacg
     1201 ctgatgggga gcaaatcgtt tactatcgtg ctgatgatga gctggatgag gctgtatttg
     1261 tagccagaac catcgatgaa cttagtcgca gtcaaaactt ccttcataag gattttgcag
     1321 ttctctatcg gactaatgcc cagtcccgta caattgagga agccctgctc aagtctaaca
     1381 ttccttatac catggttggc ggaaccaaat tctacagccg taaggaaatt cgcgatatta
     1441 ttgcttatct caaccttatt gctaatttga gtgacaacat tagttttgag cgtattatca
     1501 acgagcctaa acgtggaatt ggtctaggta cagttgagaa aatccgtgat tttgcaaatt
     1561 tgcaaaatat gtctatgctg gatgcttctg ctaatattat gttgtctggt atcaagggta
     1621 aggcagccca atctatctgg gattttgcca atatgatgct tgatttgcgg gagcagctag
     1681 accacttaag cattacagag ttggttgagt ccgtcctaga aaaaacaggt tatgtcgata
     1741 ttcttaacgc ccaagcgact ctagaaagca aggcaagggt tgaaaatatc gaagagtttc
     1801 tttctgttac gaagaacttt gatgacacca ctgatgtgac agaagaggaa actggtctgg
     1861 acaaactgag tcgtttctta aatgacttgg ctttgattgc cgacacagat tcaggtagtc
     1921 aggagacatc agaagtgacc ttgatgaccc tgcatgctgc caaaggtctc gaatttccag
     1981 ttgtcttttt gattgggatg gaagaaaatg tctttccact tagtcgtgcg actgaagatc
     2041 cagatgaatt agaagaagag cgccgtctag cctatgtagg tatcacgcgt gcagagaaaa
     2101 ttctctatct gaccaatgcc aactcacgct tgctttttgg tcgtaccaat tataaccgtc
     2161 cgactcgttt tattaacgaa atcagttcag acttgcttga gtatcaaggt ctggctcgtc
     2221 ctgcaaatac aagctttaag gcatcatata gcagtggtag tatttccttt ggtcaaggta
     2281 tgagtttggc tcaggctctt caagaccgta aacgcggtgc tgccccaaaa tcgatccagt
     2341 caagcggtct tccatttggt caatttacag ctggcgcaaa atcagcatct agcgaggcaa
     2401 attggtccat tggtgacatt gctctccaca agaaatgggg agagggaact gttctggaag
     2461 tttcaggtag cggtgctagg caggaattga aaatcaattt cccagaagta ggtttgaaaa
     2521 aacttttagc cagtgtggct ccaattgaga aaaaaatcta attttccatc cttctcacga
     2581 ataataaagt gaggaggatt tttatgtaca gtatttcatt ccaagaagat tcactattac
     2641 caagagaaag gctggccaag gaaggagttg aagcgcttag taaccaagag ttgctagcta
     2701 ttttactcag gacaggaaca cgtcaagcta gcgtttttga aattgcccaa aaagtcttga
     2761 acaatctttc aagcctaacg gatttgaaaa aaatgaccct gcaggaattg cagagtttgt
     2821 ctggtattgg gcgtgttaag gccatagaat tacaagctat gattgaactg gggcatcgta
     2881 ttcacaaaca cgagactctt gaaatggaaa gtattctcag cagtcaaaag ttggccaaga
     2941 agatgcagca ggaattaggg gataaaaaac aagagcacct ggtggcactc tatctcaata
     3001 ctcaaaatca aatcatccat cagcagacca tttttatcgg ttctgtaact cgtagtatcg
     3061 ctgaaccgcg agagattctt cactatgcaa tcaagcatat ggcgacttct cttatcttgg
     3121 tccacaatca tccttcagga gcggtagcgc ctagccaaaa tgatgatcat gtcactaaac
     3181 ttgttaaaga agcctgcgaa ttgatgggga ttgttctctt ggaccatttg attgtctctc
     3241 attctaatta ctttagttat cgtgaaaaga cagatttaat ctaaagttca ttaacgacat
     3301 agtcaaagag ttttttatct ttgggacgat tttcaaaaag aagttctgga tgccattgga
     3361 caccgagaaa ggcgacatca tccgtactca tgacagcctc aatgatacca tctttaggat
     3421 catgagccac aacttttaaa tttggtgcta agtccttgat gctctggtgg tggaaggagt
     3481 tgatatgaga gatttctcca tagatttctt ggagaacggt atctggttct gttaccaagc
     3541 gttgagttgt gtactcaaca gaagaatcct gccaatggtc ttcgatatct tggtacaaag
     3601 ttccacccat ggcaacgtta aagagttggg taccacggca gacagagaaa atgggctttt
     3661 tctgtttaat agcttccttg atgagggcca gttcgaagat atctctttga aggttatagt
     3721 catcgctatc aatggttttg ggttcgccat aaaattttgg atcgacattt tgcccacctg
     3781 tcaagatgag cttgtcaatc aaactgatat agtggcaggc catttcttga tcaccaatcg
     3841 gtaggatgat gggaatccct ccagcatctt taacgccttc aacaaagcct tttgctgcgt
     3901 agctcatcat gatgtcatca tctggatgag ctttttcgtt tcctgtaatc ccaataactg
     3961 gttttttcat aaaatgattt tcgctttcta atcctctttt cgcatgaagt agaggagggt
     4021 ttggagttca cttgtcaaat cgacatactg aacgaccacg tcttttggta aatgcagatg
     4081 gactggtgaa aaactgagaa ttcctttcac accagcatca accaagagat tagcaacctc
     4141 ttgtgacttg acgctgggaa cagttaggat agcagtcttc acatcagcat ccttgatttt
     4201 atccttgatc tgagaaatcc cgtaaatggg aatcccgtca ggagtttggg taccgacttc
     4261 aggatggtcg tctaggtcaa aggccatgat aatcttcatc ttgttacgtt cgtggaagcg
     4321 gtagtggaga agggcatggc ccatatttcc aataccaacc agcatgacat tggtaataga
     4381 gttgtcattg agcaaatcgg caaaaaatgt cattagtttt ttgacatcat agccaaaacc
     4441 acgacgacca agttcaccaa aataggaaaa atcacgacgt acggtcgctg aatcaatacc
     4501 gatagcctct gcaatttgct tagagttggc acgttcaatc ttttctgcat gaaatctctt
     4561 aaaaattcga tagtagagag agagtctttt tgctgtagct tttggaatag caaactgttt
     4621 atctttcaca aaatcacaac ctttctattc ttctatttta tagaaacatt gtgaaaaaat
     4681 caacaaaaat aagaaaaaac taagaaaaat cttagttttg atgtaaaaaa tctgcatgag
     4741 atagaaaacg gtagaggtct ccgaccagac cctgataaac tttttggccc ctaaaagtca
     4801 gagaagtcac ataaagtgta tctggtaagg ttacacatcc tgacaaagtc aacatgagag
     4861 cctcatgatc ctcatacttg agagtacgct ctacatgata gcagtcctta taggtcagtt
     4921 caaacatttt ggctctatct ttccgatttt gtaaagacac cacgttctac caagctatcc
     4981 atgaggaagt agaatttttc ctgatgaata tggtggtctt ctgatttgaa aatatcaact
     5041 agacgaaggc taaacttgtc agtgatattg attttagccc ctgtaagttc cttgttaatg
     5101 atgattttga gttggaagcc ttcaccgctg tttggcactt tttccaaaag gcgagtcagt
     5161 tcatagttac caaccttagt ttcaaaaaag gtgttatctt tgagggtgaa ttttttaaca
     5221 gaagggctaa gagtgtaatc gtaacgacaa ttttttaact gaatgatttt ttcaaatgcc
     5281 atatggctaa cctccgataa tttcttttaa ggtttttgcg agggtttgta ggtcttcaac
     5341 ggtattttgt ggcgacaaac tgatgcgaag ggattccttc aagcgttctg aatttgcgcc
     5401 atacatggct tcaagaacat ggctggattg gacaacgcct gcagtacagg ctgagccagt
     5461 agagattgaa attccagcta aatctagccg aaggagtaag aggtcatttt tctgaccagg
     5521 aaatccaata ttgagaacat aagggagatg atgttttcct ctattcaagt aatactgaat
     5581 gccctccagc tctgccagaa aggcggtttc tagattttgt acatgttgaa aatgttcttc
     5641 ttgtttttct aggtcttctt ttagggctgc aaccatgcct acgatagcag gcagattttc
     5701 agttcctgca cgttttttct gttcctggtc tccgccatgt agataggaat caaagtccat
     5761 gctagatgcg tagagaaaac cgattccctt aggaccatgg aatttgtggg cagaagcagt
     5821 gagaaaatca atgcccaatt cttctgaatg aattgggatt ttaccaatag cctgaactgc
     5881 atcaacatga taggcagcag ggtgttgctt gagtatttgg ccaatttcag cgatgggcag
     5941 taggtttcct gtctcattat tggcaaacat ggtagaaacc aaaatcgtat cgtcacgtaa
     6001 agccttttga atttgctggg ctgtgatttc ttgattttct ggctggataa tggttgcttc
     6061 aaacccaaag tgttgaacca agtaatcaat tgtttcaagg acagcatggt gctcgatggc
     6121 agttgtgatg atatgttttc cttgttcttg gtgacgaaga cagtagccaa tgatggtagt
     6181 attattgcct tcagtcccac cagaagtgaa aaagatatgt tgaggttttg tccttagtaa
     6241 ctgggctagt tcctgacggg cttctcgcaa gagtttgcca gcttgacgac catgaccatg
     6301 aatactagaa ggatttccgt gggtttcttg cataaccttg gtcatagctg aaatagcaac
     6361 tgctgacata ggagtcgttg cagcattgtc caaataaatc aaagaatcac cttatttctt
     6421 tttattgtag gcaaagagtg ggctgactgg ttttctttcg tgaatacgga cgatagcatc
     6481 accaattaac tcactagcag tgatgtagca tacattttta ggagtttttt cttttgttgc
     6541 tactgaatca gtcacaagaa tttctttaat attagtattg tcaagaagct cagcagctcc
     6601 ctcgacgaag agaccgtggc tagaaacagc ataaatttct gtagctcctt cacgttcaac
     6661 gattttagaa gcttcagaga aggtacgtcc tgtatttaaa atatcatcaa tcaagatagc
     6721 tttcttacct tcaacatcac caataatata accttcgtta cgagttgcat cgtcttgagg
     6781 gtagtcgata atggcgatag gagcatcaag atattcagcc aggctacgcg cacgtttgac
     6841 acctgaattt ttagggctaa cgacaacaac atctgaacca agcaatcctt tatcgcagta
     6901 atgttttgcg aataggggaa cagtgaaaag attatccact ggaatatcaa agaaaccttg
     6961 aacctgaacg gcatgcaaat caagagtcag gatacgatca actccagcct taaccagcat
     7021 attggcaact agttttgctg taagtggctc acgaggacaa gcaatgcggt cttgacgtgc
     7081 atagccaaaa tatggaagga caacgttgat actgtgggca cttgcacgca cacaagcatc
     7141 gaccatgatt aacaattcca ttaggtggtt gttgacaggg aaacttgttg attggatgat
     7201 gtaaacatca taaccacgga cactttcttc gatatttact tggatttctc cgtctgaaaa
     7261 ttgacgtgat gatagttttc caagtgggac accaacagct tgggcaattt tttgtgcaat
     7321 ctcttggtta gagttgagtg cgaaaagttt catgtttttt ctatctgaca ttatagaccg
     7381 tcctctgtaa actttataaa tcctagttat atttacctta catatatgaa ctgggatttg
     7441 tgtattttta tcttttctat tttaccaaaa aatggagatt atttcagcta tttttcatac
     7501 ttttgacaaa tcgaaccaat tttgaaggag ctttttggta ggaaatctga tttttctcta
     7561 aaaattgtcg gaaatcctgt ttgccttgct catgattttc cacttcaagc tccaattcgt
     7621 aatctgttat atcaaagtat cggctctgat ccagtgccat gagaccaata gctgttttca
     7681 tttcatagcg aagcgttgtt agacaaccaa gaacctgcca gttcttactt tggataccat
     7741 gtttcgccaa ttcatccagt actagtcctt gaggaagttc ttccttactc agatagtcct
     7801 cagcatcttt tagttgcaat ttttggttgt attccatgtt tccaacactc tgcgggactt
     7861 tgagtgtcaa ctcagcccag tcttcaaagg ttcgaatgcg catagcgact ttcttttctc
     7921 gcagttcaaa atcaggcgtg tcgatgtagt aatttgtttg aagaacagga gtgacacctg
     7981 tgaactggtc ttttagacga ttgtattcat cttttttcaa tagtgttttc aattcaattt
     8041 ctaaatgttt catttttctt accttttttt atcgttgaaa gcggatttat ggtataataa
     8101 gcattgtatt tattgtatat gaatctggag aaaaaatcaa agatattttt gacggataat
     8161 atgagaacaa gggagaatat atgaccttag aatgggaaga atttctagat ccttacattc
     8221 aagctgttgg tgagttaaag attaaacttc gtggtattcg taagcaatat cgtaagcaaa
     8281 ataagcattc tccaattgag tttgtgaccg gtcgagtcaa gccaattgag agcatcaaag
     8341 aaaaaatggc tcgtcgtggc attacttatg cgaccttgga acacgatttg caggatattg
     8401 ctggcttacg tgtgatggtt cagtttgtag atgacgtcaa ggaagtagtg gatattttgc
     8461 acaagcgtca ggatatgcga atcatacagg agcgagatta cattactcat agaaaagcat
     8521 caggctatcg ttcctatcat gtggtagtag aatatacggt tgataccatc aatggagcta
     8581 agactatttt ggcagaaatt caaattcgta ctttggccat gaatttctgg gcaacgatag
     8641 aacattctct caactacaag taccaagggg atttcccaga tgagattaag aagcgactgg
     8701 aaattacagc tagaatcgcc catcagttgg atgaagaaat gggtgaaatt cgtgatgata
     8761 tccaagaagc ccaggcactt tttgatcctt tgagtagaaa attaaatgac ggtgtaggaa
     8821 acagtgacga tacagatgaa gaatacaggt aaacgaattg atctgatagc caatagaaaa
     8881 ccgcagagtc aaagggtttt gtatgaattg cgagatcgtt tgaagagaaa tcagtttata
     8941 ctcaatgata ccaatccgga tattgtcatt tccattggcg gggatggtat gctcttgtcg
     9001 gcctttcata agtacgaaaa tcagcttgac aaggtccgct ttatcggtct tcatactgga
     9061 catttgggct tctatacaga ttatcgtgat tttgagttgg acaagctagt gactaatttg
     9121 cagctagata ctggggcaag ggtttcttac cctgttctga atgtgaaggt ctttcttgaa
     9181 aatggtgaag ttaagatttt cagagcactc aacgaagcca gcatccgcag gtctgatcga
     9241 accatggtgg cagatattgt aataaatggt gttccctttg aacgttttcg tggagacggg
     9301 ctaacagttt cgacaccgac tggtagtact gcctataaca agtctcttgg cggtgctgtt
     9361 ttacacccta ccattgaagc tttgcaatta acggaaattg ccagccttaa taatcgtgtt
     9421 tatcgaacac tgggctcttc cattattgtg cctaagaagg ataagattga acttattcca
     9481 acaagaaacg attatcatac tatttcggtt gacaatagcg tttattcttt ccgtaatatt
     9541 gagcgtattg agtatcaaat cgaccatcat aagattcact ttgtcgcgac tcctagccat
     9601 accagtttct ggaaccgtgt taaggatgcc tttatcggtg aggtggatga atgaggtttg
     9661 aatttatcgc agatgaacat gtcaaggtta agaccttttt aaaaaagcac gaggtttcta
     9721 agggattgct ggctaagatt aagtttcgag gtggagctat tctggtcaat aatcaaccgc
     9781 aaaatgcaac gtatctattg gacgttggag actacgttac cattgacatt cccgctgagg
     9841 aaggctttga aaccttggag gctattgagc atccattaga tattctctat gaggatgacc
     9901 actttctagt cttgaataaa ccctatggag tggcttctat tcctagtgtc aatcactcta
     9961 acaccattgc caattttatc aagggttact atgtcaagca aaattatgaa aatcagcagg
    10021 ttcacattgt taccagacta gatagggaca cttctggctt gatgctcttt gccaagcacg
    10081 gttatgccca tgcacgatta gacaagcagt tgcagaagaa atctatcgag aaacgctact
    10141 ttgctttggt taagggagat ggacatttgg agccagaagg ggaaattatt gctccgattg
    10201 cgcgtgatga agattccatt attaccagac gagtggctaa aggcggaaag tatgcccata
    10261 cttcatacaa gattgtagct tcttatggaa atattcactt ggtctatatt cacctgcaca
    10321 ctggtcgaac ccatcaaatc cgagtccatt tttctcatat cggttttcct ttgctgggag
    10381 atgatttgta tggtggtagt ctggaagatg gtattcaacg tcaggctctg cattgccatt
    10441 acctatcctt ttatcatcca tttttagagc aagacttgca gttagaaagt cccttgccgg
    10501 atgatttcag taaccttatt acccagttat caactaatac tctataaaaa ctgtctcaga
    10561 gtataattat tatcttaaag gagaaaactc atggaagttt ttgaaagtct caaagccaac
    10621 cttgttggta aaaatgctcg tatcgttctc cctgaagggg aagagcctcg tattcttcaa
    10681 gcaacaaaac gcttagtaaa agaaacagaa gtgattcctg ttttgcttgg aaatcctgaa
    10741 aaaattaaaa tttatcttga aattgaagga atcatggatg gttatgaggt catcgaccct
    10801 caacattatc ctcaatttga agaaatggtt tctgccttgg tggagcgtcg caagggcaaa
    10861 atgactgaag aagatgtacg caaggttttg gttgaagatg tcaactactt tggtgtgatg
    10921 ttggtttact tgggcttggt tgatggaatg gtgtcaggag cgattcactc aacagcttca
    10981 acagttcgtc cagctctaca aatcatcaaa actcgtccaa atgtaactcg tacttcagga
    11041 gccttcctca tggttcgtgg tacggaacgt tacctatttg gagactgtgc cattaacatc
    11101 aatccagatg cagaagcctt ggctgaaatt gccatcaact cagcaatcac agctaagatg
    11161 tttggcatcg aacctaaaat tgccatgttg agctattcta ctaaaggttc agggtttggt
    11221 gaaagcgttg ataaggtcgt tgaagcaact aaaattgctc acgacttgcg tcctgacctt
    11281 gaaatcgatg gtgagttgca atttgatgca gcctttgttc ctgaaactgc agctctgaaa
    11341 gctcctggaa gtacggtagc tggtcaagca aatgtcttca tcttcccagg tatcgaggcc
    11401 ggaaatatcg gttacaagat ggctgaacgc ctgggtggct ttgcggctgt aggacctgtt
    11461 ttgcaaggtt taaacaagcc agttaatgat ctttctcgtg gatgtaatgc agatgatgtt
    11521 tacaagttga ccctcatcac agcagctcaa gcagttcatc aatagtgaaa actataaagc
    11581 gatatactat gctatactgt agttatgaaa ctatgtacga aaagcactgc cattaattcc
    11641 tgagaactaa attactgatt ggtgtcaaaa aggaaaactt ccaagcgatg atatcctgtc
    11701 tatacacgac ctatagaaat ctgtaatatg tatgtccgta aaacgataat ttcccttttt
    11761 gattttaaat gagtatgaaa agagaatttt ttcatgagaa aacgcataat attaagtgtc
    11821 ttgacacctg ctattatgcg ttttctggct ctttgtcaac tgtagtgggt tgaagaaaag
    11881 ctaagctcga gaaaggacaa attttgtcct ttcttttttg atattcagag cggtaaaaat
    11941 ccgttttttg aagttttcaa agttccgaaa accaaaggca ttgcgcttga taagtttgat
    12001 gagattattg gtcgcttcca atttggcgtt tgaatagggt agttgaaggg cgttgacgat
    12061 tttctctttg tcctttagaa aggttttaaa gacagtctga aaaagaggat gaacctgctt
    12121 tagattgtcc tcaatgagtc cgaaaaattt ctccggttcc ttattctgaa agtgaaacag
    12181 caagagttga tagagctgat agtgatgttt caagtcttgt gaatagctca aaagcttgtc
    12241 taaaatctct ttattggtta aatgcatacg aaaagtagga cgataaaatc gcttatcact
    12301 cagtttacgg ctatcctgtt gaatgag
//
LOCUS       DAVBCA010000057        11679 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.057, whole genome shotgun sequence.
ACCESSION   DAVBCA010000057 DAVBCA010000000
VERSION     DAVBCA010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11679)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11679)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11679
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.057"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..1017)
                     /locus_tag="VQU19_001685"
     CDS             complement(<1..1017)
                     /locus_tag="VQU19_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HET2480906.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMKELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     KGEILEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESSEKFEAIKQNLVDEMWKVAQRELATGFYYGTPSENEQLFGARRKIPEYKFVAEVV
                     SYDDA"
     gene            1641..1823
                     /locus_tag="VQU19_001686"
     CDS             1641..1823
                     /locus_tag="VQU19_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HET2480907.1"
                     /translation="MANDNKSHYLIYRVLGISFEEGENIDLYQNKGRFLYKYAGSFLE
                     EAAVLSFNEKFGTENT"
     gene            1833..2198
                     /locus_tag="VQU19_001687"
     CDS             1833..2198
                     /locus_tag="VQU19_001687"
                     /inference="COORDINATES: protein motif:HMM:NF021048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HET2480908.1"
                     /translation="MPNSENTKPKTFEIDCLVGEKHAYEIKWWDATTDGDHITKEHTR
                     IKVIHNKGYIPIRLMFYYPNRTQAIKIQQTLETLYNGIGGKYYYGDSAWEHLRAVTGI
                     DLLSILTDIANKKTGVKSK"
     gene            2195..3385
                     /locus_tag="VQU19_001688"
     CDS             2195..3385
                     /locus_tag="VQU19_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HET2480909.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGADM
                     FQSEIIWNYKRWSNSKKGLLNNHQNIYFYSKSKDFKFNTIFTEYSSTTNIDQILVERK
                     RNGNSKTIYKVDNNGNYILAKEKNGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQ
                     IIKIATDKNDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLENVIKTSS
                     NLLNKGIEAYRTKTEEEENILKLLQAKIVQRNKGIDGFLPKHFQKKPIPIKIQKNNEC
                     LNESISLLQNAINSKKLDFGVVIKTHSDNLLFDFDTIPENIIVVDHFELTIEKWLSKS
                     QQLL"
     gene            complement(3900..4892)
                     /locus_tag="VQU19_001689"
     CDS             complement(3900..4892)
                     /locus_tag="VQU19_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2480910.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFYIKEEVVQNSTYSMSDYVSIYSSYIVSANGEKFNPYQTITANSL
                     CTFDFDNIKDDFVFLLHENCCYLAVSIGFKKELIEKHLASININPESFYSTLLQPNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWISIVIDTYLNRKKYKIEIDDDKAL
                     EDVARFLDDHFATNVNQGTLEKISKMSGTKLKNLFKEKYCQSITEYTQRKRMNVAETL
                     LLNTELPIKEIAESVGYSSASKFSIYYKRYKGKLPSEVRNLACKHHNFKCDYCD"
     gene            5052..6806
                     /locus_tag="VQU19_001690"
     CDS             5052..6806
                     /locus_tag="VQU19_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2480911.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISAVLTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIVTPILVLVLGFIVSIRVGI
                     ILLALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFK
                     SFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAEVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNVNNFKNY
                     NIEFENVSFAYNDKAIIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNKGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            6790..8511
                     /locus_tag="VQU19_001691"
     CDS             6790..8511
                     /locus_tag="VQU19_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2480912.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERIHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILIDGK
                     DIKEISTESLFDKVSIVFQDVVLFNQSVMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            8522..9151
                     /locus_tag="VQU19_001692"
     CDS             8522..9151
                     /locus_tag="VQU19_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HET2480913.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALIALGAFLGGILGAYIGKALLKKHFSNGLYCVGYFTPCLILWCYLN"
     gene            9052..9609
                     /locus_tag="VQU19_001693"
     CDS             9052..9609
                     /locus_tag="VQU19_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET2480914.1"
                     /translation="MYRQGSIEKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIP
                     IVIRMFILPFMAASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKN
                     IKMAMRVRGINFKNPVKYLEYVSVPLLIISSNISDDIAKAAETKAIENPIAKTRYIRV
                     KIQLIDFVYVLAVAGLIVGGLIWLK"
     gene            9597..10961
                     /locus_tag="VQU19_001694"
     CDS             9597..10961
                     /locus_tag="VQU19_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2480915.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGSGKSSLI
                     NSINGLAVRYDNAKTKGEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDILEIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDESSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKLK
                     KTYTRSEFLKLDKNELNALSLRDKELSKLKVPYLKEGGEYQIKNLSYKFTDDECLSLK
                     DISFKLGKIYGIIGSNGRGKSTLLRCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVM
                     QDVNHQLFTDEVFNELRLGVKNFDEEKAKIILKDLGLDEFIERHPMSLSGGQKQRLAI
                     ASVMCKTSPFIFFDEPSSGIDYSNMIKISELINKYKTMDKIIFIVSHDIEFLNEVADE
                     IFEL"
BASE COUNT         4258 a         1670 c         1977 g         3774 t
ORIGIN      
        1 cgcatcatca taagaaacca cttcagcgac aaacttgtac tcaggaattt tacgacgagc
       61 accaaacaac tgctcatttt cagatggtgt accatagtaa aatcctgtag ccagttcacg
      121 ttgggcaacc ttccacatct cgtccactaa gttttgtttg atggcttcaa acttttcaga
      181 actttcaaga taggcatcca cagccgcctt gtagcagttg gttactgttg atacgtagtg
      241 aatagacttc atacgtcctt cgatttttag actgtccaca ccattttcaa tcatatctgg
      301 aatgtggtca atcatagaca tatcaacggc tgacattgaa aattcttcta gaatctcacc
      361 cttcaaactc ttacgttctt tcccaaatgg catatcgtaa aggtcgtatt tccaacggca
      421 tgactgagaa cacccaccac ggttggcatc acgcatactc atgtggtttg aaagagtaca
      481 acgtccagag tatgaaatac acatagctcc atggacaaag gcttcaattt caacatctgt
      541 acgtttgcgg atttcagcta attctttcat tgaaacctca cgtgctaaaa cgacacgagt
      601 caagcctagc tctttccaga actcaagggt ttcatagtta gtggcactgg cttgggtaga
      661 aaggtggatt tcaaggcctg gtgcttcagt cgctgcaatc ataatcaagg ctgggtcaga
      721 tacgataact gctgcaatcc cgatatcacg cagtttacga aaccactcac cagcaccagc
      781 ttcatttcct tcgtgcataa ccatattagc cgctacatag accttggcac catacttggc
      841 cgcaaactgc acgccttctt ccatctgttc gaaagtaaag tttcccgcac ggctacgaag
      901 accataggcc tgaccaccga taaagacagc atctgctcca tactgaacag ctacctttag
      961 cttctctaaa gtccctgcag gtgataaaac ctcaggacgt tttaatgttt ttgtcatgat
     1021 ttctcctatt tgcaatataa aagtttgaca tttttccttc tcattttata gtaaataaag
     1081 gataaaatca agcctagacg gattgttttg acaattctaa tcttttagac tttgcataat
     1141 aactattaaa cagtcgaaaa ttaccccagt tttaacaagt agtcaaaaag tctaaaaaag
     1201 taaaaaccag tatcccaaga tactgactcg taaaaatata taaattagtc cttagatgac
     1261 tactcccact ctgttgctcc tataatggaa aaggattgat acagtctaga atatcgcttt
     1321 tttatttatt attctgatat aaaactgtta gaattgattt tttgttttat acccaaatat
     1381 gaatagagac gtagctaata agttgaataa catatttgga aaaatgagaa atagcaatat
     1441 tactagaact tttagaaaca atcaatattt aaaaagaaaa aagctcaaag aatttattaa
     1501 accatgttat aatagatata gctataattt tatttataac aagaggatag aaatgaccga
     1561 attagaaaga aaaaatcgaa aaattagcta agaaatattc tgataactta aacatcaaag
     1621 ttcaagagag agttcgtgaa atggcaaatg ataataagag ccattatttg atatacagag
     1681 ttttaggtat ttcatttgaa gaaggagaaa atatcgattt gtatcaaaat aaaggtcgtt
     1741 ttttatacaa atatgctggt tcatttttag aagaagctgc agtactatcc tttaacgaaa
     1801 aatttggtac agaaaatact taaaaagtta acattcctaa ttctgaaaat acaaaaccta
     1861 agacttttga aattgattgt ttagtcggag aaaaacacgc atacgaaata aaatggtggg
     1921 atgcaactac agatggagac catataacta aagaacacac tagaataaaa gttattcata
     1981 acaaaggata tataccaatt cggttaatgt tctactatcc aaatagaact caagctataa
     2041 aaattcagca aactttagaa acattgtata acggtattgg agggaaatat tattatggag
     2101 attctgcctg ggaacattta agagcagtga ccggtattga tttacttagt attctaacag
     2161 atattgcaaa taaaaaaaca ggggtaaaat caaaatgaca gtattaaaag gagataactt
     2221 agaaatatta aaaactattg aatcctcaag tattgattta atctatatgg accctccttt
     2281 ctttacacag aaaacccaaa aattatctaa taacaaaaat attatgtatt cattcgaaga
     2341 tacgtggact tcgattgagg attacaaaga atttttgtct gtaagattag aagaatgcaa
     2401 aagagtgcta aaaaatagtg gcagtatttt cgttcattgt gataaaattg caaatcatca
     2461 tattagatta attttagata atatctttgg agcagatatg tttcaaagcg aaattatatg
     2521 gaactataaa cggtggtcta attcaaaaaa gggattattg aacaatcatc aaaacattta
     2581 cttttattca aagtcaaaag attttaaatt taatacaatt tttacagagt attcttctac
     2641 tacaaatatc gaccaaatac tagtagaacg aaaacgaaat ggaaactcta aaactatata
     2701 taaagttgat aataatggta actatattct agcaaaagag aaaaatggag ttcccctttc
     2761 agatgtttgg aatataccat ttcttaatcc aaaagctaaa gaaagagtag gttatcctac
     2821 acaaaaacct attctgttat tagaacaaat tataaagatt gctactgata aaaatgatat
     2881 agttttagac ccgttctgtg gaagtggaac tactttagta gcctccaaga ttttgaatag
     2941 aaattatatg gggattgatt tatctgagga agctatcaat ataactcagc aacgtctgga
     3001 aaatgttata aaaacaagtt caaatttatt gaataaagga atcgaagcat atagaaccaa
     3061 aactgaggaa gaggaaaaca ttcttaaatt attacaggca aaaattgttc aaagaaataa
     3121 aggaattgat ggttttttac ctaaacattt tcaaaaaaaa ccgataccta taaaaattca
     3181 aaaaaataat gaatgtctga atgagagtat ctctttatta cagaatgcta taaactccaa
     3241 aaaacttgat tttggagtag ttataaaaac tcattcagat aatttattat ttgattttga
     3301 tacgattcct gaaaatataa tagtagttga ccattttgaa cttacaatcg aaaaatggtt
     3361 aagtaaaagt caacagttac tatagtttgc aaattattta cagaaagaac aaaaaatgct
     3421 ctgaaacact gatttcaagg cattttttgt tagtttaaaa ttactcccat tcttcttttc
     3481 caaacgtaca atatatccaa aaccattcaa aatactagat tctatttttt ataatatcac
     3541 taaatccacc taattatagg acgttttcag atttttagtc ccgtcccagt cccagtaccg
     3601 gagaaatatt gttttaatat aatatctctt tttgtcttct aagctcttaa aagcaaaaga
     3661 acaagtaaag agtcaagaca aggataaaaa gtccatatta gggcaaataa aaagctttaa
     3721 gacagatgac aaatctaagt caaataagaa agaccatagc aaaggtgcag agagataaat
     3781 attggcggtc ttcggactgc ctttattttt ttatccattt ttcaaatcaa atttattcag
     3841 actatatatg cacatataca cttaaattca tataaaaaca tggcttgtaa aaaattactt
     3901 taatcacaat aatcgcattt aaaattgtga tgtttgcaag ctaaattacg gacttcactt
     3961 ggaagttttc ccttgtatct tttataatag atagaaaatt tgctggcaga tgaatatcca
     4021 acagattctg ctatctcttt tataggtagt tcagtgttta aaagaagagt ttcagctaca
     4081 ttcattcttt ttctttgagt gtactctgta atgctttgac aatatttttc cttaaataaa
     4141 ttttttaatt tagtaccact cattttagat attttttcaa gcgtgccttg atttacattc
     4201 gttgcaaaat gatcatctaa gaatcttgct acatcttcaa gtgctttatc atcatcaatt
     4261 tcaattttat atttttttct atttaagtat gtgtcaatta ctatacttat ccattcattt
     4321 gcctttgctt taaagaaaaa atcagcggca ggagcgtcca tcttacaatt taatatttcc
     4381 attgccactc tttctaaggc ctttgtaagt attatttgat tcggttgaag caaggttgaa
     4441 taaaaagatt ctggattaat gttaatagat gctaaatgtt tttctattag ctctttttta
     4501 aaaccaatgg aaacagcaag ataacaacaa ttctcgtgta ataaaaaaac aaaatcatct
     4561 tttatattat caaaatcaaa agtacataaa gagtttgcgg taatagtttg atacggatta
     4621 aacttttctc cgtttgcact gacaatgtaa cttgaataaa ttgaaacata gtctgacata
     4681 ctataagtgc tattttgaac tacttcctct ttgatataaa aatcatgtat atcgataatg
     4741 aagctgcctc cttcataaaa ccaatatagg ccttctgcat aagttgaatt ctcttttttc
     4801 caacaaaatg tatgacctgc acttgaatac ttctcattgt ttttacattc atctactttc
     4861 atataatctt ttacaaaatc ataatatgac ataacacact atccctttta gacaatattc
     4921 caattagcct tattaattca aaactattgt attagtaatt ataacagatg tataatagaa
     4981 aagcaatgat agatattatc aattaagcga atttatatct aaaagggata ttaaagaaag
     5041 gagatatgct tatgaagatt tacaaaaaac tatttgctta tgtccaagat aagaaatatc
     5101 ttggggtttt ggccataatt ttttctgcta tatctgctgt acttacagta tatggatatt
     5161 atttaatcta caaatttcta gataagttaa taattaattc aaacttatcc ggtgcagaga
     5221 gtatagcatt aaaatctgtt attacactaa caagtggagc gatattttat tttgtctcag
     5281 gaatgttttc acatatcttg ggatttaggc ttgaaacaaa tttaagaaaa aggggaatcg
     5341 atggtctgga aaaagcaagt tttaggttct ttgacttaaa tccatctggt caaataagaa
     5401 agatcataga tgataatgca gcacaaactc atcaggtggt agctcacatg attccagata
     5461 gctctcaggc aatagtcaca cctatacttg tccttgtact tggctttata gtaagtataa
     5521 gagttggcat aattttgctt gctcttacta taattggtgg cttaatttta ggggcaatga
     5581 tgggcgagca agaatttatg aagatatacc aagaatccct atctaaacta agtgctgaaa
     5641 ctgttgagta cgtgagagga atgcaagttg taaaaatatt taaagcaaat gtagagtctt
     5701 ttaaaagctt ttataaggcg ataaaagatt actcaaagta tgcttatgat tattccctat
     5761 cttgtaaaag gccttatgtt ttgtatcaat ggttattttt tggactgatt gcaattttaa
     5821 ttattcctat agtttatttt atgactagct tagctagcgc agaggtgatt ttacttgagc
     5881 ttatcatgat tttattttta tcaggagttc tctttgtttc attcatgaga atgatgtggt
     5941 actccatgta tatttctcaa ggaaattatg cagtagatac tttagaggcg ctttacgaag
     6001 atatgcaaaa agacaaatta gtgcatggta atgtcaataa ttttaaaaac tataatatag
     6061 aatttgagaa tgttagcttt gcttataatg ataaagctat cattgaaaat ttatccttta
     6121 atttagaaga aggaaagtcc tacgcacttg tcggttcatc tggatcaggc aaatcaacag
     6181 tagcaaaact tatatcaggt ttttacaatg ttaataaagg aagcataaag ataggcggga
     6241 tagcaataag tgaatattct gacgaagcct taattaaagc catttccttt gtttttcaag
     6301 attcaaaatt attcaagaag agcatttatg ataatgtagc tttagctaat aaagatgcga
     6361 cgaaagatga cgttatgaga gccttaaaat tagcaggatg cgatttaata ttagacaaat
     6421 tcccagaaag agaaaataca atcataggct caaaaggtgt ttatttatcc ggtggagaaa
     6481 aacaaagaat tgcaattgct agagcaattt taaaggattc caaaattatt attatggatg
     6541 aagcatcagc atctattgac ccagataacg agtttgaatt gcaaaaagct tttaaaaatc
     6601 ttatgaagga taaaacagtt atcatgattg cacacaggct atctacaatt aaagaccttg
     6661 atgaaattat tgtcatggat agtggaaaaa ttatagaaag agggtctgac aaagaattaa
     6721 tgtcaaaaga tacaaggtat aagagcctgc aagagatgtt taacagtgcg aatgaatgga
     6781 gggtttcaaa tgaaagagtt ttataaaaaa agatttgctc ttacagatgg aggagcaaga
     6841 aatttaagta aagcaacact ggcttcattt ttcgtttatt gtataaacat gcttcctgcc
     6901 atattactta tgatttttgc tcaggaagtt ttggaaaata tgggcaaaag caatggcttt
     6961 tatatagtat tctcagtttt gactttgata gcaatgtata ttttgctttc tatcgaatac
     7021 gataaattat ataacacaac ctatcaagaa agtgcagatt taagaataag gacagcggag
     7081 aatttatcaa aattacctct atcttacttt tctaaacatg acatttccga catttcacaa
     7141 acaatcatgg ctgatattga aggcatagag catgcaatga gccactcaat accaaaggtg
     7201 ggcggcatgg tactgttttt cccattaata tctgtaatga tgctagcggg caatgtcaag
     7261 atgggtttag ctgtaattat tccatctatt ttaagcttta tatttatacc tttatctaaa
     7321 aaatatcagg ttaatggaca gaatagatat tatgatgtct taagaaaaaa ctcagaaagc
     7381 tttcaagaaa atatcgaaat gcaaatggag attaaagcat ataatttatc gaaggatatt
     7441 aaagatgact tatataaaaa aatggaagat agtgagagaa tacacttaaa ggcggaagta
     7501 actacaattt taactttgtc tatatcttca atatttagct ttatatctct tgctgttgtg
     7561 atatttgtcg gcgtaaatct aattattaat aaagagataa attctctcta ccttatagga
     7621 tatttactag ctgctatgaa gataaaagac tctttagatg catctaaaga gggcttgatg
     7681 gaaatatttt atttatcgcc caaaatagaa agattaaaag aaattcaaaa tcaagattta
     7741 caagaaggcg atgactatag cttaaaaaaa tttgatattg atctaaaaga tgttgagttt
     7801 gcctacaata aagacgcaaa agttttaaat ggtgtaagtt ttaaagctaa gcagggagag
     7861 gtcactgctt tggtaggtgc aagtggctgc ggtaaaacaa ctatcttgaa acttatatca
     7921 agactttatg attatgacaa gggacaaatc ttaatcgatg gcaaagatat aaaagaaata
     7981 tcaacagaat ctctttttga taaggtctct atagttttcc aagatgtggt tctctttaat
     8041 caaagcgtta tggaaaatat tagaatcggt aagcaagatg caagtgacga agaggttaaa
     8101 agagcagcaa aacttgcaaa ttgcacagat tttatagaaa aaatggataa aggtttcgat
     8161 acagttattg gtgaaaacgg agctgagcta tcaggaggag aaagacaaag attatcaata
     8221 gccagagcct tcttaaaaga tgcgccgata ttgatcttag atgagataac agcaagcctt
     8281 gatgttaaca acgagaaaaa gattcaagag tctttaaata atttagttaa agataaaact
     8341 gttgtaatca tttcacatag aatgaaatcc atagaaaatg cagacaagat agtagttctt
     8401 caaaacggaa gagtagaaag cgaaggtaag catgaagagc ttttacaaaa atcaaaaatt
     8461 tacaaaaatt taatagaaaa gacaaaaatg gcagaagaat ttatttatta ggaggactac
     8521 aatggataat aaaaaattaa aagtaaaaga tttagtaagt atcggtgttt ttggcgtaat
     8581 ttattttgcc ttcatgtttg gagttggtat gatgggcttg attccaatat tgttcttaat
     8641 atacccgaca gtattagcca tagttgcagg aactgttgtt atgttattta tggctaaggt
     8701 tcaaaagcca tgggcactat ttatatttgg tatgatatca ccacttgtga tgtttgcagc
     8761 tggtcatacc tacgtagttg tggttttatc acttatagta atgataatag cagaattaat
     8821 tagaaagatt ggtaattata attcatttaa atacaatatg ctttcttatg caatcttcag
     8881 cacatggata tgtagctctt taatgcaaat gcttttagca aaagaaaaat atatggagtg
     8941 gtctttgatg acgatgggaa aagattatgt tgatgtatta gaaaagttaa taacttatcc
     9001 tcacatggct ttaatagcct taggtgcttt cttaggagga attcttggag catatatagg
     9061 caaggctcta ttgaaaaaac acttttcaaa tggattatat tgtgtgggat actttactcc
     9121 ttgcctaatt ttatggtgtt atctgaatta aaccctatag ttaagatgtt tttgagtata
     9181 cctattgtta ttagaatgtt tattttacca tttatggcag caagctttat gataaagacc
     9241 tcggatgtag gcgcaataat ttcatcgatg gataagctta agatttcaaa gaatgtatcc
     9301 atacctattg cggttatgtt tagattcttc ccatctttta aggaggagaa gaaaaacatc
     9361 aaaatggcta tgagagtaag agggataaat tttaaaaacc cagtcaaata tcttgaatat
     9421 gtttctgtgc cactactcat tatatcatct aatatatcag atgacattgc aaaagcggca
     9481 gaaacaaagg caatagaaaa tccaattgcc aagaccagat acattcgcgt aaagatacag
     9541 ctaattgatt ttgtttatgt tttagcggtt gctggactta ttgtgggagg cttaatatgg
     9601 ttgaaataaa aaatttaagt cttgattatg gtgaagagca tatattagat gatatatcac
     9661 tatccatagc cgagggagag tgcgtgctat ttacaggaaa aagtggaagt ggtaagtcat
     9721 ctttaataaa ttcaatcaat ggactagctg taaggtatga taacgcaaag acaaagggcg
     9781 aaataattat tgatggtaag aatataaaaa atttggaact ttatcaaatc tcaatgcttg
     9841 tttcaactgt ttttcaaaat cctaagacat atttttttaa tgtcaatacg acattagaat
     9901 tattatttta tttggaaaat atcggtcttg caagagaaga gatggacagg cgtttgaagg
     9961 atatacttga gatattcccg ataaaaaatc ttttgaacag aaatatattt aatctatccg
    10021 gcggtgaaaa acaaattctt tgcattgcag cttcttatat agcaggtaca aagattatag
    10081 ttatggatga gtcttcatcg aatttagata ttaaaagcat aagtgttttg gcaaagatgc
    10141 taaagatatt aaaagagaaa ggcataagca taattgttgc agagcataga atttattatt
    10201 tgatggacat agttgaccgt gtatttttaa tagataaagg aaagcttaaa aaaacttata
    10261 ctagaagtga atttttaaag ctagataaaa atgaattaaa tgctttaagt ttaagagata
    10321 aagaattaag taaattaaaa gttccttatt taaaagaagg tggagagtat cagataaaaa
    10381 atcttagcta caaatttact gatgatgagt gtttaagctt aaaagatatt tcgttcaagc
    10441 ttgggaaaat ttatggcata ataggatcca acggacgagg aaaatcaacg cttttaagat
    10501 gtttaatagg tcttgagaaa aaatcaaaag aagaaattta ttttaaggga gagaagctat
    10561 ctaaaaaaga aagactcaaa aactcttcac ttgttatgca agatgtaaat catcaattat
    10621 tcacagatga agtattcaac gagcttagat taggagtaaa gaattttgat gaagaaaagg
    10681 cgaaaatcat tttaaaagat ttaggcctgg acgaatttat tgaaaggcat ccgatgagtt
    10741 tatcaggagg gcaaaagcaa aggcttgcaa tagcatctgt tatgtgcaag acttctccat
    10801 ttatcttttt tgacgaacct tcaagtggta tagattattc caatatgata aaaatatctg
    10861 aactgattaa taagtataaa accatggata aaataatttt tattgtttcc catgatatag
    10921 aatttttaaa tgaagtggca gatgaaattt ttgaattgta aaatagagtc tgttaaacat
    10981 gtctatagaa ctggtaaatt gtctaaaaat ttaaaagata ctaacacata ttgatattta
    11041 ttagaaaatt aacttcagga tttttacagt atttataaac tttataatat gtatttatag
    11101 tattaataat ttccatatct ttagggaaat tatttattta cttaccataa ttaaagagat
    11161 gagagataaa tatcggcagt cttcggactg cctttatttt tttacttaat ttaatgcagt
    11221 aaatcatacg attgaaagga atctgcgtta tatgctataa ttaggtagtt aatctataca
    11281 tttagaaagg taaaatatag aattggagaa tgatatggga ttttcatata ataaattgta
    11341 accacccaat aacgaagtct attgaaaaat ctccagatta gtgaactcac ggatagttcc
    11401 taatctggag atttcttatt tgcacttttc ttgtacaact ttagtccatg gtaaataagc
    11461 ctctaaaacc tctttgttta cgagagtttc ctcgtttgga agacattcta gaagatagga
    11521 tagatatttc tcgctattta taatggattg aaataagata tgaacaaatc gattaggaaa
    11581 ggaaaattga tttatagaaa tattttagca gtcgatgcgt actgttatag attcaacgca
    11641 ctataattga tgacgtttag ctgtttccaa caaactcat
//
LOCUS       DAVBCA010000058        11556 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.058, whole genome shotgun sequence.
ACCESSION   DAVBCA010000058 DAVBCA010000000
VERSION     DAVBCA010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11556)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11556)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11556
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.058"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..947)
                     /locus_tag="VQU19_001695"
     CDS             complement(<1..947)
                     /locus_tag="VQU19_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET2480916.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQVIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFILVTFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTI"
     gene            complement(1027..1890)
                     /locus_tag="VQU19_001696"
     CDS             complement(1027..1890)
                     /locus_tag="VQU19_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HET2480917.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTSLYFELNWILLQGLICQRDASYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQEAMHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(1893..3794)
                     /locus_tag="VQU19_001697"
     CDS             complement(1893..3794)
                     /locus_tag="VQU19_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET2480918.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFNDLRRTERQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETISWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLATEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENAAV
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINCVAT
                     HVLELSENGSTLYLGDYDYYVEKKATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSDQV"
     gene            complement(4222..4497)
                     /locus_tag="VQU19_001698"
     CDS             complement(4222..4497)
                     /locus_tag="VQU19_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HET2480919.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(4603..5442)
                     /locus_tag="VQU19_001699"
     CDS             complement(4603..5442)
                     /locus_tag="VQU19_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET2480920.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVIVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRIGRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            5584..6432
                     /locus_tag="VQU19_001700"
     CDS             5584..6432
                     /locus_tag="VQU19_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HET2480921.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSGWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(6525..7442)
                     /locus_tag="VQU19_001701"
     CDS             complement(6525..7442)
                     /locus_tag="VQU19_001701"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HET2480922.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            7879..8084
                     /locus_tag="VQU19_001702"
                     /pseudo
     CDS             7879..8084
                     /locus_tag="VQU19_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            complement(8395..8688)
                     /gene="rpmA"
                     /locus_tag="VQU19_001703"
     CDS             complement(8395..8688)
                     /gene="rpmA"
                     /locus_tag="VQU19_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HET2480923.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(8705..9049)
                     /locus_tag="VQU19_001704"
     CDS             complement(8705..9049)
                     /locus_tag="VQU19_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HET2480924.1"
                     /translation="MIQAVFERAEDGELRGAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENY
                     SEFVQTRVITEN"
     gene            complement(9065..9379)
                     /gene="rplU"
                     /locus_tag="VQU19_001705"
     CDS             complement(9065..9379)
                     /gene="rplU"
                     /locus_tag="VQU19_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HET2480925.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYIEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(9415..9502)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(9597..10196)
                     /locus_tag="VQU19_001706"
     CDS             complement(9597..10196)
                     /locus_tag="VQU19_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HET2480926.1"
                     /translation="MTFCAGYVDAYTFIVRGNTLVAGQAGNVVFLSVELIQNNVSDVR
                     DKLLTLITFIMGVFLLTIYKEKLRIVKKPILSLIPLAILSIIIGFVPQTVDNIYLVQP
                     LAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLAFGDYFRTKHTPFLREGFIFVSLL
                     SSFVLGDVFSAYLTIFYHEKTILGVPIMMSIFYLSMLFA"
     gene            10666..10965
                     /locus_tag="VQU19_001707"
     CDS             10666..10965
                     /locus_tag="VQU19_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HET2480927.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
     gene            11184..>11556
                     /locus_tag="VQU19_001708"
     CDS             11184..>11556
                     /locus_tag="VQU19_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2480928.1"
                     /translation="MGQLHFITKLLDIKDPNIQILDIINKDTHKEIIAKLDYDAPSCP
                     ECGSQMKKYDFQKPSKIPYLETTGMPTRILLRKRRFKCYHCSKMMVAETSIVKKNHQI
                     PRIINQKIAQKLIEKISMTDIA"
BASE COUNT         3668 a         2400 c         1919 g         3569 t
ORIGIN      
        1 aaaatcgtca taaacaattc acaaactaaa tttccagaaa aggaaagaaa agttggaagt
       61 ggtaatccca tcataaaaac tccgacacct gtcaaagcca gtaaaatcaa aagattataa
      121 atattagctt taattttact agctagaaga gccccaatga tggaaccaat agcccccata
      181 gttaaaatac ttgcataggc tccttctgac ccgtaaagct gattcgaaaa gggaagtaga
      241 aattcaaaag ctgcaaaaaa gaaattaacg ctggaagcta ccagcaaaag gaagaaaatt
      301 tcttgctgat gccagatata gtgtaaccca tccttgatat ctacaaaaat atctctccca
      361 gtaaaagcct ttttctcttg aacttttgct tcctcttttg gaaggaaagt cactagaata
      421 aaagcaatga aaaaagtcag cgagtctagc agtagcgtca tatggagact tgcaaactgt
      481 aaaacaagga aggaaagaac aggagagcta acacctacaa cctgcaaaac cagctctaag
      541 cgagaattat agatcacaat ctcatctttc tccaccactt cagttatgat agctttattg
      601 gctgtgcgag aaaaggcaaa agcaataacc tgcacaatgt tagcaacaat caaagcgcca
      661 atcatccagc tatcattcct tatgaaagaa atagccagac aaagaatccc acaaacaaga
      721 tctgccgtca ttaaaatctt acgacgagaa aaacggtctg aaataactcc gccaaaggga
      781 ttgacgagaa tagatgtgac gagctcagaa atctgataca ttcctaaaac tgtctgtcct
      841 atagtcccca tagaagccaa ccagacacta tttccataat catagagcat atttcccatt
      901 ttattgatag ccccacggct aatcaactgc actgcatagc gattcatatt aaagctcctc
      961 tcaaattttg aaactattgt atcaaaaccg aaaggagctt tttatttttt cccttatttg
     1021 ggaaaattaa cttttgacaa atttttcgta gtgttcctga taataggcta cttgctctgg
     1081 aagacctaac acatcaaaaa tatgcatggc ctcttgcatc tgcttacagc cttctttaca
     1141 ctgtcctttt tgatataagg caaaaccttt taaataatgg aaaacattac gctcataaag
     1201 cttaatacct ttgtcaataa tcttctctgt ataagcctca aaatagttgg cattataaaa
     1261 agaagaatgc tctaaacaat gctggtaaca attgagggcc aaaatcaaca ctaatctctt
     1321 atggcgacta atctcttggt aaaattcctc cctctccata acttctctac caatccgagt
     1381 gacatagtct acatcgtaga aactatagag gttaccgaaa agaatcaact catacatggt
     1441 ccattcttct gttttgaaga gataatctgc taccttatcc aaatcatcct gcttcatatc
     1501 ataactcgca tctctttgac aaatcagacc ttgtagcaaa atccagttca gctcaaaata
     1561 aagggaagtc gtcgaactct tagacttttc aagttgttct ctttgaagct tttgaaaacc
     1621 tgcaatatcg tttgaatagt aaagtgggat aatctgtgcc atcatagaca catgttcatg
     1681 attatgaaaa ttccttgcct tatccatgaa attttcgatt gttacatgaa tgttatccaa
     1741 aatctcaaag aaacgggaga ctgccaggtc agactcccca agctcaaagc gagataactg
     1801 agaggtagag caggattcgc ctgctgcttc ctttaaagaa taatttccac ttgttcgaaa
     1861 ttcacgaaat acttttccaa gatgttccat ctttacacct gatctgataa ttcttcccac
     1921 tcaagcatag cttcttcctg acgatggctg attttatcca gctcagcctg taattccatg
     1981 agtttgtcgg catcgtttgt ttccaacatt tgttcagaaa tggcttggct ttgactttct
     2041 agctcttcaa tttcagcttc tagactttcg atttgtcgca tgagtttgcg aacttctttt
     2101 tgactttctt tctgggcctg atagtcattg actggacttg cttcctttgc ttgattgcta
     2161 gttgaagctt cctcagtctg actcatttct gctgttgctt tcttctcaac atagtagtcg
     2221 taatctccaa ggtagagagt tgaaccattc tcagacaatt ccaaaacatg agttgccaca
     2281 caattgataa agtaacgatc atgactgaca aaaagcaagg taccatcaaa gtcaatcaag
     2341 gcattttcta gcacttcctt actatcaata tccaagtggt tggtcggctc atccagaatc
     2401 aaaaagttat tgttttccat agacaattta gctaaaagca aacgagcttt ttcgccacca
     2461 gatagcatgc cgactgattt tttaacatca tctcctgaga aaaggaaggc tccaagacgg
     2521 ttgcggattt caacttctgg tgtcaatttg aaatcattcc agagttcatc cagcaccgta
     2581 ttacttggtg tcagcttgct ttgggtttgg tcatagtaac caacctcaac attagcgcca
     2641 aagcgctttt ctcccttgat aaacggaatt tgatccacga ttgatttgat aaaggttgat
     2701 tttccgatac cattgggacc aacgatagca acagcattca tcttacgaag gtctaggtta
     2761 atcggttgtg acaggacttc cccatcatag ccaacagccg cattttcaac agtcaaaaca
     2821 acattgcccg acgttttttc agactggaag gtcatgttgg ctgctttctt gccagcttcc
     2881 ggcttgtcca aacgctccat tttttctagt tgtttacggc gagattgagc acgtttggtc
     2941 gttgaagcac gaactagatt gcgattgaca aagtcttcca gagcagcgat ttccttctgt
     3001 tgcttttcat agttttttgc ctcagtagct agcttttgct ccttcaactc gacaaaacga
     3061 gagtaattcc ccacatagcg atccaaggaa tgcttggtca aatctagcgt aattgtcgca
     3121 accttgtcca agaaataacg gtcgtggctg acgataatga gggcaccgct atagtttacc
     3181 aagtaattct ctagccagga gatggtttca atatccaagt ggttagttgg ctcgtccaag
     3241 accaagagat tgggcttttc aaggagcatt ttagctagag ccaaacgagt attttgacca
     3301 cctgaaagtt cagctatttt catctgccac atagactcgt caaacttgaa tccattcaaa
     3361 atcgctcgaa tatcagcttc ataggtaaag ccacctgctt ggcgaaaatt ctcagataag
     3421 cggtcataat ctgacatcag tttatccaaa tcctcaccag acttttcacc catctccagc
     3481 tccatctgac gcagttgtct ctccgtccga cgcaaatcat taaagacatg aagcatttca
     3541 tcgtagatgg tattttcaga ctcaaaacgg ctatcttggg ctaggtaaga cagagaaata
     3601 tcttttttct tattgatttc tccgctagtt ggctcctctt ctccaactaa aatcttcaaa
     3661 agagtagact tacctgcacc atttttccca acaagagcaa tccgatctcg ttcatcaacc
     3721 tgcaggttga tattatcgaa aagaacctct cctgcaaaag aacgttcaat tttattagct
     3781 tgtaaaataa tcataagagt agtatagcat gtttccctaa ggcattcaag ataatcgtaa
     3841 gtcttttagt acaactttta taacataaaa taaactaaat tatgtatatt ttatattaga
     3901 ttccttcact atcttgttgg attttctaac cagctaatct tgtttcaaat agttatcgca
     3961 caagcctatt atttaattct tttcattatt tacgtacgcg tatagcagat tgaaataaga
     4021 tgagaacaaa tcgattggga aagtaaaatt aatttctata aatgttttag caattgtttc
     4081 gtactatttt agattcagtc tactatgtac aatattttcg gaacattcaa ctttttaact
     4141 ctatttatta ctagatttca taattaaaaa gcctactgac caagctagaa agcttgatac
     4201 aataggcttt ttaaagactg attatttaac agcgtcttta agagctttac cagctttgaa
     4261 tgctggtact ttagaagctg caattgtcat ttctttacca gtttgtgggt tgcgaccttt
     4321 acgttctgca cgctcacgaa cttcaaagtt accaaaaccg atcaattgaa ctttttcacc
     4381 agctgcaaga tagtcagcta ctgctgcaaa tacagcttca actgctgctg ctgagtcttt
     4441 cttagtcaat tctgtagctt ctgctacttt agcgatcaaa tcttgtttgt ttgccatgtt
     4501 aatgattcct ccagataatt tctaattaac aaatataatc atatcctaaa atccctttta
     4561 ggtcaagtta aaaacgctat ttcttccaat tttatttatt ttttaggagt ggtaacgtat
     4621 caaaatagcc caagcgttct cacccgtgtg agtttgaata atggaacccg tttccaaaac
     4681 agaaattggc ttttcaacat aagcttgtaa gctttctttc atctcttttg cccaatcatc
     4741 actaccagaa tatgaaattc caatctctgc tacagcacgt tcagaaagcg atgttatcaa
     4801 ctcatctaac cattttttaa atgttttagt tccacgacct ttaaccattg gctgcaattc
     4861 atggtctttc atttgcatga caacacggat attgagaagg gagctcaaca agccagttac
     4921 acggccaatt cgtccacctt tgacaagatt ttccaaagtt gaaacaccaa tataaagctc
     4981 tgtatggttt ttaacctctt ctacatgaga taaaattgcc tccatatctt taccttcttg
     5041 agctaacttc gcagcctcaa caacttggaa tttcagggct tggtcagtga aggaactatc
     5101 aacaacaatc acatctgcag tagataggct agcaccttgg cgtgctgctt ctaccgtacc
     5161 cgaaagagca tgggacatat gaatagcaag aatctggcca ccatctttgc ataggtcttc
     5221 aaaaatctca gcaaagacac ctacaggtgg ctgacttgtt ttcggaagat tcttactttc
     5281 ttgcatcaac tgaagaaatt taccttcttc tttcaaatcc gcatcagaat aaacaacatt
     5341 atcaatcatt acagataatg gaacaattgt aatatctaat tgctttacta gttcaggttc
     5401 aatagtaaca gatgaatcgg ttacaatctt aatttttgtc atagtatcaa tctttctatt
     5461 ttaggattca gattggtttc cttacttcta attatatcaa aaaaaagatt aaaaatccta
     5521 atggagtcaa tcaaattttc cgtaaaattt gatataatca acttataaga aaagaggtgt
     5581 cctatgatta aaaaaattta ccccattttt accattttac taggtgctgc tatttatgct
     5641 tttggactga cttattttgt agttccccat catctctttg aaggaggggc gacaggtatt
     5701 accctcatca cattttatct ttttaaaatc cctgtttccc tcatgaacct gctgattaat
     5761 attccccttt tcatcctagc ttggaagatc tttggagcca aatccctcta ttctagttta
     5821 ctaggaacct tagctttgtc cggctggtta gctttttttg agcatattcc ccttcatatt
     5881 gatcttcaag gtgatttact aataacagcc cttatagcgg gaatcctatt gggaattggc
     5941 cttggaatta tttttaatgc tggaggtaca actggcggaa ctgatattct agctcgtatt
     6001 ctcaacaaat acactcatat atccatagga aaactgctct ttatcttaga tttttgtatt
     6061 ctcatgttga ttctcctaat cttcaaggat ttgagattgg tttcctacac gcttttgttt
     6121 gattttattg tttctcgtgt tattgatttg attggtgaag gaggatatgc cggcaaaggc
     6181 tttatgatta tcacaaaacg tcctgaccaa cttgctaagg cgattaatga tgacctcgga
     6241 agaggtgtta cttttatttc tggtcaaggc tactatagta aagaaaattt gaaaatcatc
     6301 tactgtattg tcggaagaaa tgaaattgtg aaaacgaagg aaatgattca tcgaatcgat
     6361 cctcaagcct ttataactat tacagaagcc catgaaatcc taggagaagg cttcaccttt
     6421 gaaaaagaat aaaaagaggt aatgtcgtga cctcaaaagt tagactaaat catctatctt
     6481 ttgggttaca gacaacctct tttttgtttt atttactcaa gctcttaaga ccaattccga
     6541 gttacttctt catcagcctt taactgatcc actaattggt caactgagtc aaatttggtc
     6601 atatcacgaa tgcgatcaag ccaataaacc atgacggttt ccccataaat atcttgatta
     6661 aaatcaaaaa tattgacttc aaaacgtgct tcttctccat caaaggtcac atttttcccg
     6721 acactagcca tagcacgata cttctgtctt tgaatctcaa catcaacgac ataaacgcca
     6781 tctgctggca tataagtacg gtctaaaagc actaaattcg ctgtcggata accaattgta
     6841 cgaccacgag cattaccatg aaccaccata cctcttgatg gaagcggtgc ccccaaaagt
     6901 tttcctgctt ctttcacatt tccatctaaa atagcttgac ggatacgagt tgaactaatc
     6961 tttcctttct catcttctac aggtggaaca atgataactt ctccatcaaa gtaatccttt
     7021 aaatcttctg ctgttttttt gtcagaacca aatgtataat caaaacctgc aacaataatt
     7081 ttggcattca tagccttgat ataagttgca aagaattctt gtgcagtgag actagcgaat
     7141 tgactactaa aatcaaggag atataattct tctacacctt cgcgctttaa ttttctttca
     7201 cgttcagcag ggttcaaaat atgcaaaaac aaatccggat gataaggctc taaagcgatc
     7261 tttggagatt cattaaaggt cataacgacg ataggtaata aatcctttct cgcagccttg
     7321 ttggcaacac gaaataattc ttgatgcccc ttatgtatgc catcaaaata gccgagaaca
     7381 acgactgaat cagatggtgt gccaatatct ttttggtttt ttataggaat agtaataatc
     7441 ataaaataat tatatcatag cgatagctat ttctggaaca gaaaatctga aatgttgttt
     7501 ttttcacatg aagtgtacct gttttcaaaa agcactttat tctatcgttg cttaactatg
     7561 aactttgcaa tattcttctc aaaaacttgt aggacatctt caaaattttg caaggagtga
     7621 ttagacttgt tcggtaacca taaagtgtca tactatgtta tgtatgaaaa agcaatgcaa
     7681 ctaactcctg agaactttaa attactaatt ggtgccgaaa aggtagaatt tagaatcgag
     7741 gtacacctat ggctgtaaaa tttacaaaat gagacaactt gggcaagatg tttgaagaat
     7801 ttcctaaact ccctgatttg aagcaagtca ctttccctga tgacaaagaa aaaagccaaa
     7861 acagcaaaga aaaactagat gactgctttc caacaactcc catctagtgt gcttcagact
     7921 gggctatttt tctctccatc tgttagcttg gattctcaga ccgtttcagc taaagaatat
     7981 cttttccctt atcagaagga acggctcaaa ccattcagac aagtgaaggg acgacaagcc
     8041 aatatttgaa accagatagc agttcttata gtcaattgaa ataaaatctg aagaaatcga
     8101 gtaggaaact catatcaatt tttaacagtg ttctattcca gattcatact caatgaaaat
     8161 taaagtgcaa actaggaagt tagccgcagg ctgtacttga gtacggcaag gtgaaactga
     8221 cgtggtttga atttgatttt cgaagagtat caatccacta tacatattaa aaagtatgga
     8281 tatcaaaaca aaaaaacagg ctctccgaaa actcggaaag ccttatttta agctgtttct
     8341 agcttcctca cctttacatt tcaaggttcg ggataaaagg ttcaatggac ctttttattt
     8401 agcgattggg taaacagaaa cttgtttttt atcgcgtcct ttacgttcaa agcgtactac
     8461 gccttcaact ttagcgaaca aagtatcgtc tccaccacga ccaacgttta cacctggata
     8521 gatgtgtgta ccacgttgac ggtaaaggat tgatccacct gttacagttt gtccgtcagc
     8581 tgctttagct ccaagacgtt ttgcttgtga atcacgtccg tttgatgtag aacctccacc
     8641 ttttttgtgg gcgaaaagtt gcaagttgtt aagagtcatt tttaacataa tgttttcctc
     8701 cgtgttagtt ttctgtgata actctggttt ggacgaactc agaatagttc tccgataagt
     8761 ttgccatacc taagaaaaat gattcaaaga ataactgggt catttctctc tggtgtgaag
     8821 gaagatcttt tggtatttca accatcagat agccaccttc atcttcgttt aattctagga
     8881 ttggttcata gcctgcaaat ttctcaatag aattgataaa gttaatggca agcgtagaaa
     8941 ccgatgcaca cacgacatct aagccgtatt cgccactctc ggcgtgtcca gtaatttccg
     9001 cacccctcag ctcgccatct tcggctctct caaagactgc ttgtatcatg tgttctcctt
     9061 aaaattaagc gttaattgcg ttgatgacaa cttttgtata tggttgacgg tgaccttgtt
     9121 tacggtggct acctttttta ggtttgtact tgtaagtaac aactttcttt tgttttcctt
     9181 gtttttcaac agttccaact acagtagctc cagcaacaag tggagttccg acaacagtgt
     9241 tttcaccacc aacaagaaca acttcgttaa aagtaacttc ttgaccagct tcaacgttca
     9301 atttttcaat gtaaactgct tgaccaactt caactttaac ttgttttccg ccagttttga
     9361 taattgcgta tgtgctcatt atgcacctcc tatgattttt atgggtttcc ccgatttttt
     9421 gtgaagactc gcctagcatc gtgggacaaa ccacttaaac ttgaataatc aagcaacgat
     9481 gttcgtgcgg ttgcacagga tcgtgcatag tcaactcttc aagtatagca tatctcctat
     9541 tttcttacaa gtaataacac ctaaaatcaa gctttttctt ttactttttt ctgccactag
     9601 gcaaaaagca tactgagata aaaaatgctc atcataatag gaacaccaag aatggtcttt
     9661 tcatgataga aaatcgtcaa ataggctgaa aagacatcgc caaggacaaa actactaagc
     9721 aggctaacaa atatgaaccc ttcacgcaaa aaaggagtgt gcttagttcg gaaataatct
     9781 ccaaaagcta gcattgttcg tttgatattc cctgtcataa aggcattatt gtaggcaata
     9841 cccgaaacct caccaaaagc agttgtcacc agtcccatac agaaggccaa gggctgcact
     9901 agatagatat tatctacagt ttgtggcaca aaaccaataa ttattgatag gattgctaaa
     9961 ggaatcaagg acagaatagg ttttttcaca attctcaatt tttccttata aatcgttaat
    10021 aaaaagactc ccattataaa cgttattaag gttaaaagct tatccctaac atccgaaaca
    10081 ttattttgta ttagctctac cgaaagaaag acaacatttc cagcttgtcc agctacaagg
    10141 gtattccctc gaacaataaa agtgtaagca tccacatatc cagcacaaaa tgtcaaaaaa
    10201 gtgctaacct tttagactga cgtgatattt ttcttatagg taataacctc attttccctc
    10261 ccattgtatt ttctcttaga aatattgtac catttctttc taaaaaatcg tagactacca
    10321 tttagatttt actattagca taaaaataat aatagacaac tatttatcca aaaatagata
    10381 gaggtaacat gtttgcaaac aaagcatacg aacctttagt aaaatcattt ccatgaaact
    10441 agaatagagc ccctcttagc aaaaatcatt attttaattt atttctaatc actccttgac
    10501 ataaataact ctcaccaata aaagactatg tcttaaaaaa atggtataat aaaatcaata
    10561 cctgggcttg atggctatgc tactaataac aattaggaga gaaaatcagg cacttgttaa
    10621 caacaaggat tatccccttg agatgaaagg aactttagaa atcttatgat gaacatgcaa
    10681 aacatgatgc gtcaagcaca aaaacttcaa aaacaaatgg aacaaagcca agctgaactt
    10741 gctgctatgc aatttgttgg caaatctgct caagatcttg tccaagcgac cttaactggc
    10801 gataagaaag ttgtcagcat tgatttcaat ccagctgtcg ttgacccaga ggaccttgag
    10861 actctttctg atatgaccgt tcaagccatc aactctgctc ttgaacaaat cgatgaaact
    10921 actaagaaaa aactgggtgc tttcgctggg aaattgccat tctaaaaaca aggagctaga
    10981 acaatacttg tcgataacaa aggctaagaa aggtgcaaaa attataaaaa acgcatagta
    11041 tcaagcaacc taaaactttg ggctctataa tatttgtagt gggtaaatcc actatagata
    11101 ttatggagcc tattttattg tagaaaaaaa tcccataaga tctataatga aaagcgacca
    11161 aacaactcat tagaaagatt catatgggac aattacattt tatcacaaaa ttactagaca
    11221 ttaaagaccc taatatccag attttagaca tcatcaataa ggatacacac aaggaaatca
    11281 tcgccaaact ggactacgac gccccatctt gccctgagtg cggaagtcaa atgaagaaat
    11341 atgactttca aaaaccgtct aagattcctt accttgagac aactggtatg cctactagaa
    11401 tcctccttag aaagcgtcga ttcaagtgct atcactgttc aaaaatgatg gtcgctgaaa
    11461 cttctatcgt caagaagaat caccaaatcc ctcgtatcat caaccaaaag attgctcaaa
    11521 agttaattga aaagatttct atgactgata ttgccc
//
LOCUS       DAVBCA010000059        11318 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.059, whole genome shotgun sequence.
ACCESSION   DAVBCA010000059 DAVBCA010000000
VERSION     DAVBCA010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11318)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11318)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11318
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.059"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(7..1221)
                     /locus_tag="VQU19_001709"
     CDS             complement(7..1221)
                     /locus_tag="VQU19_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET2480929.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(1377..1670)
                     /locus_tag="VQU19_001710"
     CDS             complement(1377..1670)
                     /locus_tag="VQU19_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480930.1"
                     /translation="MMKNSFQKSNFLYYGIILVSVLVKVIMICQLESLVPLLYPSFIG
                     FLVFHVLYHLILFLVAKRSGRWDYLMIWGLFLMFNLLYDSFLGLLFLGLSFGM"
     gene            1832..2284
                     /locus_tag="VQU19_001711"
     CDS             1832..2284
                     /locus_tag="VQU19_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HET2480931.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(2319..3707)
                     /locus_tag="VQU19_001712"
     CDS             complement(2319..3707)
                     /locus_tag="VQU19_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET2480932.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQALDKAAGKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            3773..4735
                     /locus_tag="VQU19_001713"
     CDS             3773..4735
                     /locus_tag="VQU19_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HET2480933.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
     gene            complement(4732..4923)
                     /locus_tag="VQU19_001714"
     CDS             complement(4732..4923)
                     /locus_tag="VQU19_001714"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480934.1"
                     /translation="MNTIERTRRLVKGCATHCFEVVDETDEVSSKHVFEVVDRTDEVS
                     NHTYGRATLTWFAEIFEEY"
     gene            complement(4987..5997)
                     /gene="ccpA"
                     /locus_tag="VQU19_001715"
     CDS             complement(4987..5997)
                     /gene="ccpA"
                     /locus_tag="VQU19_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HET2480935.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKVGITYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(6422..7021)
                     /locus_tag="VQU19_001716"
     CDS             complement(6422..7021)
                     /locus_tag="VQU19_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2480936.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRSERLETKVVVVTTFKRAGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEVVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(7022..8119)
                     /locus_tag="VQU19_001717"
     CDS             complement(7022..8119)
                     /locus_tag="VQU19_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET2480937.1"
                     /translation="MLERLKSIHYMFWASLIFMIFPILPVVTGWLSAWHLLIDILFVV
                     AYLGVLTTKSQRLSWLFWGIMLIYVAGNTAFVAVNYIWFFFFLSNLLSYHFSVRSLKS
                     LHVWTFLLAQVLVVGRLLIFQRIEVEFLVYLLGILTFVDLMTLGSVRIRLVEDLKEAQ
                     TKQNTQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQIQAYPQVEKELR
                     EIQQISKESMREVRTIVENLKSRTLTSELETVKKMLEIAGIEVEIANQLDTASLTQEL
                     ESTASMILLELVTNIIKHAKASKAYLKLERTDQELLLMVRDDGKGFETVTENELHTVR
                     ERVLPFSGEVSVISQKHPTEVQVRLPYKERK"
     gene            complement(8119..8856)
                     /locus_tag="VQU19_001718"
     CDS             complement(8119..8856)
                     /locus_tag="VQU19_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2480938.1"
                     /translation="MKRWIALNKIEFLLTKRQSVYYLLSVGMPTAFYLFFSGMYQDTP
                     GGPANFMRDYLISMTAFSMMSTAIFSFPAVLHTDKMNNWQKTLRHSPVNMVEYYLSKI
                     TSMMVDYLVSILVVFSVGHLVRGVDMSLGSWIGAAFLLIVGSIAFVALGLTLTLLPSS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQAIGKCLPTYQLMELLKTFLNEGSINL
                     SATVYLLVFSAVLFGLTIYLQGHKENA"
     gene            complement(8858..9742)
                     /locus_tag="VQU19_001719"
     CDS             complement(8858..9742)
                     /locus_tag="VQU19_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2480939.1"
                     /translation="MNMIKVQGLHKNIKSKAILKDISFEVAEGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVYIQDLPVTSSKLDYTRSYLPQENVIVQKLKVKELIAFFQRIY
                     PNPLNNQEIDQLLQFDQQQKEQFAEKLSGGQKRLLSFILTLIGRPKLVFLDEPTAAMD
                     TSTRQRFWEIVRDLKAQGVTILYSSHYIEEVEHTADRILVLNKGELIRDTTPLAMRSE
                     EIEKHFILPLAYKEVVEKSVLVENWVQKQDALQVVTCEADAFWELLVQAGCRIQEIEV
                     NNRSLLDTIFEETQKGDD"
     gene            complement(9729..9923)
                     /locus_tag="VQU19_001720"
     CDS             complement(9729..9923)
                     /locus_tag="VQU19_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480940.1"
                     /translation="MKKAILFLFIGLSLVVWLVEMFTGWFDQSFLHQVIRGAWGLGFM
                     ISVVFPMGMEWLKGEYYEHD"
     gene            complement(9920..10126)
                     /locus_tag="VQU19_001721"
     CDS             complement(9920..10126)
                     /locus_tag="VQU19_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480941.1"
                     /translation="MEEEEMRNKMIIAVSLVVAGVMTYLMFSGLDEGFYHFPWELFAS
                     FGIMSWLIREGLKLVRDVKKELEK"
     gene            complement(10611..10684)
                     /locus_tag="VQU19_001722"
     tRNA            complement(10611..10684)
                     /locus_tag="VQU19_001722"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10648..10650),aa:Pro,seq:tgg)
     gene            complement(10700..10773)
                     /locus_tag="VQU19_001723"
     tRNA            complement(10700..10773)
                     /locus_tag="VQU19_001723"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10737..10739),aa:Arg,seq:acg)
     gene            complement(10783..10868)
                     /locus_tag="VQU19_001724"
     tRNA            complement(10783..10868)
                     /locus_tag="VQU19_001724"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10832..10834),aa:Leu,seq:taa)
     gene            complement(10876..10947)
                     /locus_tag="VQU19_001725"
     tRNA            complement(10876..10947)
                     /locus_tag="VQU19_001725"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10913..10915),aa:Gly,seq:gcc)
     gene            complement(10970..11042)
                     /locus_tag="VQU19_001726"
     tRNA            complement(10970..11042)
                     /locus_tag="VQU19_001726"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11007..11009),aa:Thr,seq:tgt)
     gene            complement(11061..11142)
                     /locus_tag="VQU19_001727"
     tRNA            complement(11061..11142)
                     /locus_tag="VQU19_001727"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11106..11108),aa:Leu,seq:tag)
     gene            complement(11148..11220)
                     /locus_tag="VQU19_001728"
     tRNA            complement(11148..11220)
                     /locus_tag="VQU19_001728"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11185..11187),aa:Lys,seq:ttt)
     gene            complement(11245..11317)
                     /locus_tag="VQU19_001729"
     tRNA            complement(11245..11317)
                     /locus_tag="VQU19_001729"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11282..11284),aa:Asp,seq:gtc)
BASE COUNT         3401 a         2619 c         2087 g         3211 t
ORIGIN      
        1 caagccctat ctacgatact gtttcaagaa acgagtcatc ttttcttgga tttgggctaa
       61 ctcatcaaca cgaggaaggt aaacgatacg gaagtggtct ggttcctgcc agttaaagcc
      121 tcgaccatga accaagagaa ccttttcctg cttcaagaaa tcaaggacaa actgctcatc
      181 atcatcgata cggtacatat tgcggtcgat ttttgggaag atatagagcc ccgccttggg
      241 tttaacggca gacaaacctg gaatatcttg aatggcatta tagatgaaat ttctttgctc
      301 gtagattcgt ccaccaggaa gaagcaattc atcgactgat tggtgacccc ccaaggaagt
      361 ttgtacgact tgttgggcca aaacgttaga gcaaaggcgc atattggaca gcatattgag
      421 cccttcgata tagcccttaa catgagtctt agggccagac aagaccatcc aacccacacg
      481 gaaacctgct atgcggtggg attttgacag accattcatg ctgacacaga agacatctgg
      541 tgccaagctc gccacaggcg tatgcacatg tccgtccatt accatgcggt catagatttc
      601 atccgcaaag ataatcaaat cgttttgacg ggcaatctca ataatctcca gcaagagttc
      661 cttaggataa agggctccag ttgggttatt tggattgata aggacaattg ccttggtatt
      721 ggaagtgatt tttgacttga tatcgtcaat atctgggtac cattccacag cttcatcaca
      781 gatatagtga acggcatttc ctccagctag gctgacagcc gccgtccata gaggatagtc
      841 tggcattggc actaagacct catccccatt gtccaaaagc ccctgcatgg acatgacaat
      901 caactcactg acaccatttc caaggtaaat atcatcaata tctacgtttg ggaatttctt
      961 cagctggcaa tactgcatga tggccttacg ggctgagaaa atccctttgg agtcagaata
     1021 gccttcacta tcacgcgcat tcataatcaa gtcatgaatg acctcgtctg gcgctgtaaa
     1081 gccaaattct gctggatttc ctgtattcag acgtaaaatc ttttctccat tcgctcgcat
     1141 ccgcatggct tcttccaata caggaccacg gatatcataa gcaacatgct ctaacttact
     1201 agacttgtta tattctttca tcttgtttcc tcaattcatc aggatagtaa cattatacca
     1261 ctagaaagag aatgcgacaa gtttactgaa atgtgttact agtttcgtat agaagaaaaa
     1321 ccttgctaaa ggcgaggtta agaacgtaga gatagcaggc attttgcaaa gacacatcac
     1381 ataccaaaag ataaacctag aaaaagcaag cctagaaagg agtcataaag aagattaaac
     1441 atgaggaaaa gcccccatat catcaagtaa tcccaacgcc cacttcgttt tgcaactaga
     1501 aataagatta gatggtagag tacatgaaag actaaaaatc caataaaact tggataaaga
     1561 agcggtacca gactctctaa ttgacagatc atgatcactt ttaccaagac tgaaactagg
     1621 ataattccat aatacaggaa atttgatttt tgaaaagagt ttttcatcat tctcccttcc
     1681 ttcacttctt tccttctatc ctttctttta ttttatcata tatttatata gattttaagc
     1741 cctaatattc ttttgaaaaa tacttttttt gctttacttc tatagtgaaa aggtttacaa
     1801 ttatagtaag aaaatttcag gaggtttcat tatggcacaa cgttaccaaa atatcatggt
     1861 cgcaatcgat ggttctaagg aagcggactt ggcttttgtc aagggagttc attctgctct
     1921 acgaaacgac gctaaactca ccatcgcaca tgtcattgac acacgcgctc tccaaagcgt
     1981 atccaccttt gatgctgaag tttacgaaga actccaagtc gacgctgaaa gtctgatgaa
     2041 agagtacgaa aaacgtgcta aagatgctgg ggtagcagat gttcatatcg tcattgaaat
     2101 gggaaatcca aagaccctgc tagcacgtac tattccagat gccgaggaag tggacctcat
     2161 cctcgttggc gcaactggtc tcaacgcctt tgaacgcctc ttggtcggct cttcatctga
     2221 atacatactc cgccatgcta aggtcgattt gctggttgtg agagaacaag aaaaaacctt
     2281 ataatcacaa agaaaaggag cccctagctc ctttttgttt acgatttatt tctctcttta
     2341 tggcgttcgt aagccttgag ctggcgctgc agttcctttt taatagcagg ttctggagca
     2401 tatttttctt cccaattatc tggttttaag attttatggg tcactggatc aaaatgagcc
     2461 ttgccatctg gaaaaatttt ccccatattg gcctgatgga caatatcaaa aatacgttct
     2521 gggtccaccc ccatcaagac aaaactgccg taggtgaagt aaagcgtgtc aatcaaggca
     2581 tccacttgcc ctatcaaatc ttgctgagca ggtgtcttct tggctacttt acctgctgcc
     2641 ttatcaaggg cctgatgaag ttgcgataca gcttgaccaa aatcttcttc agaaggactg
     2701 gctgctcgaa caaactccac caattcttct attttaaaac cagccctatg ggttgcaccc
     2761 tctaaatccc aagctcgagg ttcttcttgg gttcgttcat ccatcatgtg gtggaaggtc
     2821 ttgaccttat tgaaatgata gtcacggctg acaaagactt tttctgaaga caaaacacca
     2881 aaatgttcca aggccttgtg gatcccatct tgttgattgc tagtggtaat gtgcttggca
     2941 gcttccttga cactgctact accatttccc atagcgaccg acataccgac gccagccagc
     3001 atttcaaggt cattatctga gtcaccaaaa gccatgactt ggttgaggtc aaagccatat
     3061 tctttcccaa ctcggcgaat gccttctaat ttagaatttc cctgattgat gacatccgat
     3121 gcaaaaggat tgctacgtgt caatttcaag tcttcaaaat cagctgccgc cttctcagat
     3181 tcttctggtg tcatcagcat caaaacttgg tagataggct gattcatcag gtgaagcagg
     3241 tcctcttcct tttggggaac aaccttgctg accatgcgat taaaagactg actcaccgtc
     3301 cgagttaaaa cagagggaac gaagcgacta attcgttggg aaaaagaacc cagaccaaag
     3361 gacatgattt tagaacccaa catggcatcc ttggtcccta gggcaatctc cgtgccctct
     3421 tttttagcat agctaattag atggcgcaaa tgtaacttgg aaatagggct cgtgaacaag
     3481 actctgtctt tactaaagat atactggcca ttataggtta ccgcaaaatc cagatccaaa
     3541 tcgtccatca attccttaac aaaaaaaggt cctcgccctg tcgctacgcc aactagtacc
     3601 ccttgttctt tgacaatctt aatcgcgtcc ttagtggatt tcaaaacact cttgcgattg
     3661 ttgaccaagg ttccatcgat atcaaaaaaa acagctttga cttccatcct attccaatct
     3721 ccccttttgt gatacaatga ttataccaca tttcagaaag agtgagtaaa tcatgcctaa
     3781 gaaaatcctt gttttacata cgggtggaac tatttccatg caggccgatg cttctggcgc
     3841 tgttgtgacg agttcagata atcccatgaa ccatgtgtcc aacccacttg aaggaatcca
     3901 agtccacgcc ttggactttt ttaaccttcc aagtccccat atcaaaccca aacatatgct
     3961 ggtcctctac cagaaaatta aagaggaagc agataactac gatggagtgg taatcacaca
     4021 cggaaccgat actttagagg aaacagccta tttccttgat accatggaag ttccccatat
     4081 gcctatcgtt ctaacaggag ccatgcgtag ctccaatgag ctcggtagtg atggtgttta
     4141 taattaccta agtgctttac gagtggccag cgatgacagg gctgctgaca aaggagtttt
     4201 ggtcgttatg aacgatgaaa tccacgctgc caagtatgtc accaaaacac atacgactaa
     4261 tgtcagcacc ttccagactc caacacatgg ccccctcggt ctcatcatga aacaggaaat
     4321 cctctacttc aaaacagctg aacctcgtgt tcgctttgac cttgatcaca tacaaggttt
     4381 agtccctatc atctcggctt atgctggtat gacagatgag ctgattgata tgctggattt
     4441 agaacacttg gacggtttga ttatccaagc cttcggagct ggtaatattc ccaaagaaac
     4501 ggctcaaaaa ttagaaagcc ttctgcaaaa aggaatccca gtcgctctgg tatcacgatg
     4561 ctttaacggt attgccgagc ctgtttatgc ctaccagggt gggggcgtac agttgcaaaa
     4621 agcaggcgtt ttctttgtta aagaactcaa cgcccaaaaa gctcgcttga aactcctcat
     4681 cgccctcaat gccggactaa caggacaggc tttgaaagac tatatggaag gctaatactc
     4741 ttcgaaaatc tctgcaaacc acgtcagagt cgccctaccg tatgtatggt tactgacttc
     4801 gtcagttcta tctacaacct caaaaacatg ttttgagctg acttcgtcag tttcatctac
     4861 aacctcaaaa cagtgtgttg cgcagccttt aaccagccgc ctagtccgct ctatggtatt
     4921 cattaagtca acatctcttg tttaagagca caaaatcagg aaatcttctc gattccctga
     4981 ttttttctat ttacgttttc gtgttgagct acgttctgtc aaaccatgag gtaagagaac
     5041 ttcacgttct tccaactctt ccttatgcat aatcttggtc aacatacgca tactaatggc
     5101 accaaggtca taaagaggtt gggcaatcgt tgtcaagttt ggacgggtaa agcgtgagat
     5161 ttgtgaatca tcactagtaa taatttcaaa atcttctggc acagaaacac ccttatcagc
     5221 caaaccgttc aagactcctg ctgccaactc atcacctgtc acaactgctg cagttgcatt
     5281 tgatgaaatc aaacgctctg ctaaggcgta accatcatca tagctatatt tagattcaaa
     5341 taccaaaccc tcactataag tgattcctac ttttttcaag gtttccttgt agccaactaa
     5401 acgaacctta ccattgatgt catccactag cggaccgcta acgaaagcaa tacgctcatt
     5461 ttctttagca aggtagctca ctgcatcaat tgttgcttgc ttatagtcaa tattgacact
     5521 tggcaactgg tgctcaacat cgacagttcc tgcgagaaca atcggagtac gtgaacgcga
     5581 aaattctgag cgaattttat ctgtcaagtg ataacccata tagataatgc catctacctg
     5641 ctttgaaaag agggtattga caacagaaac ttctttctcg ttatcttcat cgctattagc
     5701 taggacaata ttgtacttgt acatttctgc aatatcatca atccccttag ccaaactcga
     5761 aaaataacca ttggtaatat ttggaatcac gacaccgaca gtggttgtct ttttacttgc
     5821 aagaccacgc gcaactgcat ttggacgata atccaaacga tcaattacct ctagcacttt
     5881 tttacgggta ttctctttta catttttatt gccattgacc acacggctga ccgtcgccat
     5941 ggaaacacct gcttcacgag cgacatcata aatggttact gtatcatctg cattcattcc
     6001 ttttcctgtc ctttctatct cacacattct tttacaagta gaggtactga ttgaagctct
     6061 atatctactt acaaaagtga agatgtgaaa atttcgtttt catatttcta cttattccat
     6121 tctatcacta attgtaaaca ctttcaagtg ttttttgaag attgattgaa aaaatttcat
     6181 agaaaaccta ggtttagctc cttgctacca ccttagacta aataaaaagg aggaaactaa
     6241 gcccttctaa agttatagta aaatgaaata agaacaggat aaatcgatca ggacagtcaa
     6301 atcgatttct aacaatgttt tagaagtaga ggtgtactat tctagtttca atctactata
     6361 ggtattgttc cattcactac cgtcaatttt agcacatagt cttcatgaaa atattatatc
     6421 atcataacca accagattct tttgcgatat tagctgcctc tgttcgatta ccagcatcca
     6481 gttttgaaag aatattggtg acatagtttc gaatagttcc gtttgagagg taaagctgat
     6541 ctgcgatttc ttggttggat aagccccggg cgattccctt taagacagca atctcttgtt
     6601 ctgtcaacgg attgggacgg gtcatcacca cttccatcaa ttcaggcgaa tactccttgc
     6661 gtccttcgag gacggtgtgc aaggtttgca tgaggtctgc aatgcttcgt tcctttaata
     6721 cataagcatc cactccagcc ttgaccgcac gttcaaaata cccagcacgc ttgaaggtcg
     6781 tcaccacaac cacctttgtt tcaagccttt ctgatcgtat ccactccaag acttcaagac
     6841 ctgtcttaac aggcatttct acgtcaagga tggcgatatc tacagactcc ttttctaata
     6901 gttggattgc ttcttgccca ttcttggctt gaaggacaga ctccacatct ggttgaagcg
     6961 tgagcaattg acacatagca tctcgcaaca tactttgatc ttctgcgact aatactttca
     7021 tctactttct ctccttataa ggtagtcgaa cttgcacttc cgttggatgt ttctgactga
     7081 ttacacttac ttctcctgaa aatggaagga cacgttctcg aactgtatgg agctcatttt
     7141 ctgttacagt ttcaaaacct ttcccgtcat ctctgaccat caggagcaat tcctgatctg
     7201 tgcgttctaa ttttaagtag gctttagacg ctttagcatg tttgatgatg ttggtcacta
     7261 attcaagcaa aatcatggaa gccgttgact ctaattcctg agttaagcta gctgtatcta
     7321 gttgattagc tatttccacc tcaattccag caatttctaa catctttttc acagtctcta
     7381 gttcggatgt caaagttcta gacttaagat tttccacaat ggttcgcact tcacgcattg
     7441 attctttgct aatctgctgt atttctctta attccttttc cacttgtgga taagcctgta
     7501 tttgaaataa ctgcaaggct agatcagttt taacactaag catagcaaag gtatgcccca
     7561 gactatcatg caaatcttga ccgatacgat tgcgctcatt ttctgctagc aatagattta
     7621 tctgggtatt ttgcttagtc tgagcttctt tcaaatcctc gacaaggcga attcgaaccg
     7681 agcccaaagt catcaaatca acaaaagtaa gaattccaag cagatagact agaaactcaa
     7741 cttcgattct ctgaaaaatc aaaagtcgcc ccacaacaag gacttgagca agaagaaaag
     7801 tccagacatg taaagacttt aaactacgta cgctgaaatg ataacttaag agattggaaa
     7861 ggaaaaagaa aaaccagata taattcacag caacaaaggc ggtattccca gctacataga
     7921 tcagcatgat cccccagaaa agccaagata ggcgctggct cttagttgtt aaaacaccca
     7981 aatatgccac tacaaataga atatcaatca ataaatgcca ggcagaaagc cacccagtca
     8041 ctacaggtag gatggggaaa atcataaaaa ttaaactggc ccaaaacata tagtgtatgc
     8101 ttttcagtct ttcaagcatt aagcattctc cttatgacct tgaaggtaaa tggtcaaacc
     8161 aaacaaaact gctgaaaaaa caagtagata aactgtggct gatagattga tgctaccctc
     8221 gtttaagaag gtcttgagca actccatcaa ctgataagtt ggtaggcact tcccgattgc
     8281 ttgcatccag tctggaaata aagagatggg catccagagt ccacctaaaa cagccaagcc
     8341 tagatagaga agattgccca cgacagacat cagctgacta gaaggcaaga gtgtcaaggt
     8401 caagccaagc gctacaaaag ctatacttcc tactatcagc aagaacgcag ccccaatcca
     8461 gcttcctaaa gacatatcca cacctctgac caagtgccca actgagaaaa caaccaggat
     8521 tgagaccaaa taatcaacca tcatacttgt tatctttgat agataatatt ctaccatatt
     8581 tacagggcta tgacgcaatg ttttctgcca gttgttcatc ttatcggtat gtaagacagc
     8641 tgggaatgaa aagatagcgg tcgacatcat ggaaaaggca gtcatggaga tgaggtagtc
     8701 gcgcataaaa ttagccggtc cacctggtgt gtcctggtac atgcctgaaa agaatagata
     8761 gaaggctgtc ggcatcccta cagataataa ataatagact gattgccgtt tggtcaatag
     8821 aaattctatc ttgtttagtg caatccatcg tttcatctta gtcatctccc ttctgtgttt
     8881 cttcaaagat tgtatccaac aaactacgat tattgacttc gatttcttgt atcctacatc
     8941 ctgcttgaac taacagttcc cagaaagcat ccgcttcgca tgtgactact tgtaaggcat
     9001 cttgtttttg tacccagttt tcaaccaaga ctgacttctc aacgacttcc ttgtaagcta
     9061 gcggaaggat aaaatgcttt tcaatctcct cactacgcat agctagaggc gtcgtgtcac
     9121 gaatcaactc tcccttattt aaaaccaaaa tccggtcagc tgtatgctct acctcttcaa
     9181 tataatgaga cgaatagaga atggtgactc cttgcgcttt taggtcccga acaatttccc
     9241 aaaaacgttg acgagttgaa gtatccatgg cagcagttgg ctcatctaaa aagacaagct
     9301 ttggtcgccc aattaaggtc aagataaaag ataaaagacg cttttgccca cctgacaatt
     9361 tttctgcgaa ttgctctttc tgttgctggt caaactgtaa tagttgatcg atttcctggt
     9421 tgttcaaggg atttggatag atacgttgaa agaaagcaat caactcttta acctttagtt
     9481 tttgaacaat tacattttct tgagggagat aggatctcgt atagtctaac ttagagctcg
     9541 ttaccggcaa atcttggata tatacttgcc cactggtgac caatttatct ccaagcaaac
     9601 agtccaagag tgtcgtctta ccagctccat ttggcccaat caaggcgacg cattcacctt
     9661 cagctacctc aaaggaaata tccttcaaaa tagccttact tttgatgttt ttatgtaagc
     9721 cttgtacctt aatcatgttc ataatattct cctttcaacc actccattcc catagggaaa
     9781 acgacggaaa tcataaatcc taatccccag gcgccgcgaa taacttggtg aagaaaggat
     9841 tgatcaaacc aacctgtaaa catttctacc aaccatacca ctagtgatag tccaataaaa
     9901 agaaagagaa tcgctttttt catttttcaa gctccttttt cacatctctt actaatttca
     9961 agccttctcg tatcaaccaa gacatgattc caaagcttgc aaacaactcc caaggaaaat
    10021 gatagaatcc ttcgtccaat cctgagaaca tgagataagt catgactcct gctactacta
    10081 aactcactgc gataatcatt ttatttctca tctcttcttc ctccatttca tactacaatt
    10141 atagtctttt gaaatcagag gagatagaag cttctgtcac taaaaaatat gacaaatgtc
    10201 ataaaaaatt ctgttcaaaa caagcaagat acactataca ataaaacaca attagataaa
    10261 tctaaggcaa cttcctcaaa agagatatca aaccccattc acactataat gtaaactaat
    10321 acttatttaa agtcaaaaga gcggaaattt ttatcgtaca aacatatata ttataggtaa
    10381 gacaaaaaac tcttcaatta ctttcttaaa aatttatagg agttataaaa tctattaaat
    10441 ttcaatgtgg atacctaaac tacagtattt attgaaaaga ctggagacaa aaagtatacg
    10501 ctgccaaaat gaattgctga aaatcaaaaa agagagaagc aaactgattc tctcttaatg
    10561 tatataatat ctagttataa aaatacacac tcacatatct ctgtaatgaa tcgggaagac
    10621 aggattcgaa cctgcgacac cttggtccca aaccaagtac tctaccaagc tgagctactt
    10681 cccgagttaa atagaaaaat gcaccctaga ggagtcgaac ctctaaccgc ctgattcgta
    10741 gtcaggtact ctatccagtt gagctaaggg tgctccatat tatgccgagg accggaatcg
    10801 aaccggtacg atcgttacca atcgcaggat tttaagtcct gtgcgtctgc cagttccgcc
    10861 accccggcct ctctaagcga acgacgggat tcgaacccgc gacccccacc ttggcaaggt
    10921 ggtgttctac cactgaacta cgttcgcact gttttcttct atctaaaaat gccggctaca
    10981 tgacttgaac acgcgaccct ctgattacaa atcagatgct ctaccaactg agctaagccg
    11041 gctcatttgt tatatcttaa tgcgggttaa gggacttgaa cccccacgcc gttaagcgcc
    11101 agatcctaaa tctggtgcgt ctgccaattc cgccaaaccc gcatatatga cccgtactgg
    11161 gctcgaacca gtgacccatt gattaaaagt caattgctct accaactgag ctaacgagtc
    11221 taaaataact tgcgttacct taaacggtcc cgacgggaat cgaacccgcg atcttcgccg
    11281 tgacagggcg acgtgataac cgctacacta cgggacct
//
LOCUS       DAVBCA010000060        11268 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.060, whole genome shotgun sequence.
ACCESSION   DAVBCA010000060 DAVBCA010000000
VERSION     DAVBCA010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11268)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11268)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11268
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.060"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..77
                     /locus_tag="VQU19_001730"
     CDS             <1..77
                     /locus_tag="VQU19_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET2480942.1"
                     /translation="MPQSPWVERIVQVLDLDYEDLFRR"
     gene            80..667
                     /locus_tag="VQU19_001731"
     CDS             80..667
                     /locus_tag="VQU19_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2480943.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCSDELTILQILYGASLIS
                     FLWMYGQRKQVIKVNMKTRIQWLGIGFVSLLIISLCFSLIHAQESTNQANLIGLQHQI
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHPGTIIAWCLYV
                     SLGMFLGLVRYKLDLWGSMGLHLVWNLLVYSLLLF"
     gene            1066..1875
                     /locus_tag="VQU19_001732"
     CDS             1066..1875
                     /locus_tag="VQU19_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000926538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HET2480944.1"
                     /translation="MLLQKELIPMIEANLPNMAYAEKDIAKFFLKQQPLNNYSCKALC
                     ECLNVSKATLTRFAKKCGFKGFRQFIFKYQEMIREKEKLALYTEATEKVLSDYEEMLR
                     KTYTVLDEVQLERIAEMIETAERVYLYGKVSSVLALQEMKMRFMRLGVIGEVLSDEDM
                     ILWNSLLLNENCLVIGASVSGQTDIVLEGLQKAADKGAKTVLMTTRKFDEEDCFFDEL
                     LLLASTNHLSYGNRISPQFPILLITDCLFSHYLESPERQYYYNQTIIHKEE"
     gene            1880..2581
                     /locus_tag="VQU19_001733"
     CDS             1880..2581
                     /locus_tag="VQU19_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET2480945.1"
                     /translation="MSQIWTKEKFISQVHGGVIVSCQALPGEPLYNEEFSLMPFMAKA
                     ALEAGAVGIRANSVRDIKAIQKVVDLPIIGIIKRDYPPQEPYITATMKEVDELVECGT
                     TVIAFDATLRPRYDGLVINEFIKKIKEKYPNQLLMADVSNFDEGLYAFKSGVDFVGTT
                     LSGYTSTSVQSDEPDFELMKKLADFNIPVIAEGKIHYPEQLKKAYSLGVTSVVIGGAI
                     TRPKEIAQRFINVIK"
     gene            2606..3523
                     /locus_tag="VQU19_001734"
     CDS             2606..3523
                     /locus_tag="VQU19_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HET2480946.1"
                     /translation="MKDLTKYKGVIPAFYACYDENGEISQERVKSLVQYFIDKGVKGI
                     YVNGSSGECIYQSVEDRKQIIEAVMEVAKGKLTVINHVACNNTKDSIELAKHSESVGV
                     DAIAAIPPIYFKLPEYSIAAYWNAMSEAAPNTDFIIYNIPQLAGVALTGSLYATMRQN
                     PRVIGVKNSSMPVQDIQMFVAAGGEDYIVFNGPDEQYLGGRLMGAEAGIGGTYGVMPD
                     LFLKLESLIQERDLDTAKKLQYAINEVIYKMISGKANMYAVAKEVLRLNEKLDLGSVR
                     QPLEALAEGDLEVAKQAAELIQQARKEFL"
     gene            3551..5092
                     /locus_tag="VQU19_001735"
     CDS             3551..5092
                     /locus_tag="VQU19_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HET2480947.1"
                     /translation="MGTTGFTIIDLIILIVYLLAVLVAGIYFSKKEMKGKEFFKGDGS
                     VPWYVTSVSIFATMLSPISFLGLAGNSYAGSWILWFAQLGMVVAIPLTIRFILPIFAR
                     IDIDTAYDYLDKRFNSKALRIISALLFIIYQLGRMSIIMYLPSAGLSVLTGIDINILI
                     ILMGAVAIVYSYTGGLKSVLWTDFIQGVILISGVVLALFVLMANIKGGFGAVAETLAN
                     GKFLAANEKLFDPNLLSNSIFLIVMGSGFTILSSYASSQDLVQRFTTTQNIKKLNKML
                     FTNGVLSLATATVFYLIGTGLYVFYQVQNAGSAASNIPQDQIFMYFIAYQLPVGITGL
                     ILAAIYAASQSTISTGLNSVATSWTLDIQDVISKNMSDDRRTKIAQFVSLAVGLFSIG
                     VSIVMAHSDIKSAYEWFNSFMGLVLGLLGGVFILGFVSKKANKQGAYAALIVSTIVMV
                     FIKYFLPPTAVSYWAYSLISISVSVVSGYIVSVLTGNKVSAPKYTTIHDIPEIKADSS
                     WEVRH"
     gene            5111..5569
                     /locus_tag="VQU19_001736"
     CDS             5111..5569
                     /locus_tag="VQU19_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET2480948.1"
                     /translation="MIISEQSDFRRYASINKHFSKVCDFLENTNLTDLVDGKVDIDGE
                     NVFANCMIYLADGVPGDIFETHKKYLDIHIVVENTEKMAVTSPVRAQSRVPFSEEKDI
                     AFYDSKDYQIVELLPGNMLVTFEEDLHQPKIHCNDEPVKKLVIKVLNEEK"
     gene            5571..7793
                     /locus_tag="VQU19_001737"
     CDS             5571..7793
                     /locus_tag="VQU19_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exo-alpha-sialidase"
                     /protein_id="HET2480949.1"
                     /translation="MKKNIKQYVTLGTAVVLSAFVANSVAAQETETSEVSTPELVQPV
                     APTTPISEVQPKSGNSSEVTVQPRTVETTVKDPSSATEETPVLEKNNVTLTGGGENVT
                     NELKDKFTSGDFTVVIKYNQSSEKGLQALFGISNSKPGQQNSYVDVFLRDNGELGMEA
                     RDTSSNKNHLVSRPASVWGKYKQEAVTNTVAVVADSVKKTYSLYANGTKVVEKKVDNF
                     LNIKDIKGIDYYMLGGVKRAGKTAFGFNGTLENIKFFNSALDEETVKKMTTNAVTGHL
                     IYTANDTTGSNYFRIPVLYTFSNGRVFSSIDARYGGTHDFLNKINIATSYSDDNGKTW
                     TKPKLTLAFDDFAPVPLEWPRDVGGRDLQISGGATYIDSVIVEKNNKQVLMFADVMPA
                     GVSFREATRKDSGYKQIDGNYYLKLKKQGDTDYNYTIRENGTVYDDRTNRPTEFSVDK
                     NFGIKQNGNYLTVEQYSVSFKNNKKTEYRNGTHVHMNIFYKDALFKVVPTNYIAYISS
                     NDHGESWSAPTLLPPIMGLNRNAPYLGPGRGIIESSTGRILIPSYTGKESAFIYSDDN
                     GASWKVKVVPLPSSWSAEAQFVELSPGVIQAYMRTNNGKIAYLTSTDAGTTWSAPEYL
                     KFVSNPSYGTQLSIINYSQLIDGKKAVILSTPNSTNGRKHGQIWIGLINDDNTIDWRY
                     HHDVDYSNYGYSYSTLTELPNHEIGLMFEKFDSWSRNELHMKNVVPYITFKIEDLKKN
                     "
     gene            7833..8942
                     /locus_tag="VQU19_001738"
     CDS             7833..8942
                     /locus_tag="VQU19_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HET2480950.1"
                     /translation="MVNYGIVGAGYFGADLARSMNKIEDAKVVAVFDPNHGEEVAQEL
                     GSDVCASLDELVAREDIDCVIVASPSYLHREPVVKAAQHGKHVFCEKPIALSYEDCKA
                     MVDACKENNVIFMAGHIMNFFNGVHHAKELITQGKIGKVLYCHAARTGWEEQQPTVSW
                     KKLRSQSGGHLYHHIHELDCIQFIMGGLPEKATMVGGNVYHKGENFGDEDDMLIVNLE
                     YSDDRYAVLEYGNAFRWGEHYVLIQGTEGAIKLDLFNTGGTLRVKGEGESHFLVHETQ
                     EEDDDRTAIYTGRGMDGAIAYGKPGVRCPLWLQTCIDKEMEYLHDIIKGGEITEEYEK
                     LLNGVAALESIATADACTLSVKEDRKVSLSEITNA"
     gene            9099..9989
                     /locus_tag="VQU19_001739"
     CDS             9099..9989
                     /locus_tag="VQU19_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET2480951.1"
                     /translation="MKIIGIDIGGTTIKADLYNEFGTSLNQFKEIETIIDYDLGTNQI
                     LNQVCDLIGEYILNHSIDGVGISTAGVVNANTGEIIYTGYTIPGYIGVNFTFEIEKRF
                     GLSTFVENDVNCAALGELWKGQAKDKKNVVMVTIGTGIGGSIIVNGQIVNGFNYTAGE
                     VGYIPVGNSDWQSKASTTALIHLYQKKSLKTNQTGRTFFTDLRAGDKVAKETFEIFVE
                     NLTKGLLTITYLLNPEILILGGGILAKKDILLPEIQSSLAKNAMDNRFLPKNLVAATL
                     GNEAGRIGAVKNFLDRISNK"
     gene            10014..10337
                     /locus_tag="VQU19_001740"
     CDS             10014..10337
                     /locus_tag="VQU19_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480952.1"
                     /translation="MTNSVFSTMQDIENVATDIIKSYDNEIYTYKAVSQEELEKLEKS
                     YDEKSHEELVSIESNLEMKQQNLIDEVNKTIKENYEKIQYISSSRRGEFVEKIIGRVV
                     EKYGY"
     gene            10327..>11268
                     /locus_tag="VQU19_001741"
     CDS             10327..>11268
                     /locus_tag="VQU19_001741"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018351.1"
                     /note="Produces ATP from ADP in the presence of a proton
                     gradient across the membrane. Subunit I is part of the
                     membrane proton channel; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HET2480953.1"
                     /translation="MAISQMKRISLLFSKSSLDDVLKTIQELESVQFRDLKVQDNWSE
                     ALEKDEVVFPTIQISHTSNSNHGVIEGNDALIYLMNQQQYLEATVEKLQEYLPKENTF
                     KLLQQPPITTSYEELEKFGKANVAEGVLKKVNRQINRVHELERHIQSNNEEIERLIKW
                     EKLEIIPAHLEQFFFCKGKVGTIPRTVDNRLYNSFLENNIEVQEIFSNDREYGVVVFY
                     QSSCSIDFDEYLFEPFDYSRKELPKQRVVDLDQENMQLITEKENIIASLQDSKNNLID
                     LQWQIDYILSIYARQISKNNLLSTPHLVALEGWIEETR"
BASE COUNT         3873 a         1616 c         2202 g         3577 t
ORIGIN      
        1 gaatgcctca aagtccatgg gtagaaagga ttgtgcaggt attagattta gattatgaag
       61 atttatttcg gaggtaatta tgaaaagaat aattccagtt tatatattcc aacaagtaaa
      121 tgtcctattg gtatctctat acttattgaa atttctttgt agcgatgagt taactatact
      181 acagattctc tatggagcgt cactcatttc ttttttatgg atgtatggtc aacgaaaaca
      241 agtgatcaag gttaatatga aaactaggat acaatggctt ggtattggat tcgttagcct
      301 actgattata agtctatgtt ttagtctaat ccatgcgcaa gaaagcacga atcaagcaaa
      361 cttaattgga cttcaacatc aaattccttg gttttcattt ttattgtttt taatcaatgc
      421 gagtatggtt gaagaatttc tgtatagaga aattttatgg aacttggtta gaaaattaga
      481 tattcgagtt gctttgacaa gtgttttatt tgccttagca catcatccag gaaccattat
      541 agcttggtgt ttgtatgtat cgctggggat gtttttaggg cttgtacgct acaaattgga
      601 cttatggggc agtatggggc tacatttggt gtggaaccta ctagtttata gtttgctgct
      661 tttttaaaat aagtgatctg atttatctca taaatcagta gtttttatag gattattttt
      721 aattcggaaa caaaaatgta ttaacagcat aaaataaaga aactaggaac atttttttta
      781 ttttttagaa ataaaatgtt gtatagaaat tccgaaagaa ataataaaat caaaataaaa
      841 attaataaaa taggtatatt tgaacatatt gacgtcgaca aatgttcttg caagacataa
      901 aatacaaata aaaagaataa aaaattttta tatttttata tttgttgttc tgttataaaa
      961 tgaaagaaat tagaaactag tttctaaatc atgaaaaata ttgaaaaaaa aaaaataagt
     1021 gttaaaataa agaatgtaaa cgtttacttc aataaaggag ctcatatgtt actgcaaaaa
     1081 gaactaattc caatgataga agctaactta ccaaatatgg catatgctga aaaagacatt
     1141 gctaaattct tcttaaaaca gcaacctctg aataattatt catgtaaggc attgtgcgaa
     1201 tgccttaatg tatccaaagc aacattgact cgatttgcga aaaaatgtgg ttttaaaggt
     1261 tttagacaat tcattttcaa ataccaagag atgattcgtg agaaagaaaa gttagcattg
     1321 tatacagagg ctacagaaaa agttttatcc gactatgaag aaatgttgag aaaaacttac
     1381 acggttcttg atgaagttca acttgagcgt attgctgaga tgatagaaac tgctgagcgt
     1441 gtatatcttt atggtaaagt aagttctgtt cttgctttac aagaaatgaa gatgagattt
     1501 atgcgtctcg gagtcattgg tgaagtatta tcagacgagg atatgatttt gtggaatagc
     1561 ttattactta atgaaaattg ccttgtcatt ggagcatccg tttcaggtca aactgatatt
     1621 gtactagaag gtcttcaaaa agctgcggat aaaggcgcta aaacagtttt aatgactaca
     1681 agaaaatttg acgaagaaga ttgtttcttt gatgaactat tgttattagc ttcgaccaat
     1741 catctctcgt atggcaatcg catatcacct cagtttccaa tacttttaat tacagactgc
     1801 ttattctctc attatctgga aagtccagag agacaatatt attacaatca aactattatc
     1861 cataaggagg aataataaaa tgagtcaaat ttggactaaa gaaaaattta taagtcaagt
     1921 ccatggtgga gtcattgttt cttgtcaagc tttacccggt gaaccccttt ataatgaaga
     1981 atttagcttg atgcctttta tggctaaagc agctttagag gcaggagcag tgggcattcg
     2041 cgcaaattct gtgcgtgata ttaaagcaat tcagaaagta gtagatttac caataattgg
     2101 aattatcaaa agagattatc cacctcaaga accatatatt actgctacga tgaaagaagt
     2161 agatgaactt gtagaatgcg gaacaacagt cattgcattt gatgcaactt taagaccaag
     2221 atatgatggc ttagttatca atgaatttat caaaaaaata aaagaaaaat atcctaatca
     2281 attgttgatg gcggatgtaa gtaattttga tgaaggtctc tatgcattta aatcaggcgt
     2341 tgattttgtt ggtacaacat tatcagggta cacaagtaca agtgtacaat cagatgagcc
     2401 tgattttgaa ctaatgaaaa aattggctga ttttaatatt ccggtaattg ccgaaggaaa
     2461 aattcattat ccagaacaat taaaaaaagc ttatagttta ggtgttacca gtgttgtcat
     2521 tggtggagcg attacacgtc caaaagaaat tgctcagcga tttattaatg tcatcaaata
     2581 aaaaacaata taaaggagaa atctgatgaa agatttaact aaatacaaag gcgttattcc
     2641 tgcattttat gcttgctatg atgaaaatgg tgaaattagc caagaacgtg taaaatctct
     2701 ggtgcaatat ttcattgaca aaggtgtaaa aggtatctat gtaaatggtt cttcaggtga
     2761 atgtatttac caaagtgtag aagatcgtaa acaaattatt gaagctgtta tggaagttgc
     2821 taaaggtaaa ttaacagtta tcaaccatgt tgcatgtaat aacacgaaag atagtattga
     2881 attggcaaaa cattcagaaa gtgttggagt cgatgctatt gctgctatcc cacctattta
     2941 cttcaaattg ccagaatatt caattgcagc atattggaat gcaatgagtg aagctgcgcc
     3001 aaatacagat tttatcattt ataatattcc acaattggca ggggttgcgt tgactggtag
     3061 tttgtatgca acaatgcgtc aaaatcctcg tgtgattgga gttaaaaatt cttctatgcc
     3121 tgtacaagat attcaaatgt ttgtagctgc aggtggagaa gattacattg tattcaatgg
     3181 tccagatgaa caatatcttg gtggtcgctt gatgggagca gaagctggta ttggtggtac
     3241 ttatggcgtt atgccagatt tgttcttgaa attggaaagt ttgattcaag aacgagattt
     3301 agatactgct aaaaaacttc aatatgctat caatgaagtt atctataaga tgatatcagg
     3361 taaggcaaat atgtatgctg tagcaaaaga ggttttgcgt ctaaatgaaa aacttgattt
     3421 aggttctgtt cgtcaaccct tagaagcatt ggcagaaggt gacttggaag ttgcaaaaca
     3481 agcagcagaa cttattcaac aagcacgaaa agaattttta taataaataa aatcaatatg
     3541 gagatatgtt atgggcacaa caggatttac aataattgac ttaattatct tgattgttta
     3601 tttacttgcg gtgttggttg caggtatcta tttctctaaa aaagagatga aaggaaaaga
     3661 gttcttcaaa ggagatggtt cggttccttg gtatgttact tcggtatcca tttttgccac
     3721 aatgctcagt ccgatttcct tcttgggact cgctggtaac tcttatgcag gtagctggat
     3781 tttatggttt gctcaattag ggatggtagt agctattcca ctgacaattc gttttatctt
     3841 acctatcttt gcacggatag acatcgatac ggcatatgat tacttggata aacgttttaa
     3901 ttctaaagca cttcgtatta tttcagcact cttgtttatt atttatcaat tgggacgtat
     3961 gtctatcatt atgtacctcc catcagctgg tttatcagta ttgacaggaa ttgacatcaa
     4021 tattttgatt attttgatgg gtgcagttgc aattgtttat tcttacactg gtggtctaaa
     4081 atccgtatta tggacagact ttattcaagg tgtgattctg attagtggtg tcgttttagc
     4141 tttatttgta ctgatggcta atattaaagg tggctttggt gcagtagcag aaacattagc
     4201 aaacgggaaa ttccttgctg caaatgaaaa acttttcgat cctaacttgc tttcaaactc
     4261 catcttttta attgtgatgg gttcaggctt tacaatcttg tcttcctatg cttcatctca
     4321 agatttggtt caacgtttta ctacaacaca aaatattaag aaacttaata agatgttgtt
     4381 cacaaacggt gtcttgtcac ttgcaactgc aacagtcttt tacttgattg gtacaggctt
     4441 gtacgtattc tatcaagtac aaaatgcagg tagtgcagct agcaatatcc ctcaagacca
     4501 aatctttatg tactttattg cataccagtt accagtaggt atcacaggtt tgattttggc
     4561 agcgatttat gcagcatctc aatcaactat ttcaacaggt ttgaactctg ttgcaacttc
     4621 atggacattg gatattcaag atgtcatttc taaaaatatg tcagacgatc gtcgtacgaa
     4681 aattgcacaa ttcgtatctc tagcagtagg tttattctca attggtgttt ccattgtcat
     4741 ggctcactca gatattaaat ctgcatacga atggttcaat agcttcatgg gacttgtact
     4801 tggtctactt ggtggtgtat ttattcttgg atttgtttct aaaaaagcaa ataaacaagg
     4861 tgcttatgca gcgctgattg tatcaactat cgtcatggta tttattaaat acttccttcc
     4921 tccaacagct gtgagctact gggcatattc attgatttca atctctgtat cagtagtttc
     4981 aggttatatt gtatctgttc ttactggaaa taaagtatct gcacctaaat atacaacgat
     5041 tcatgatatt ccagaaatta aagcggattc aagttgggaa gttcgtcact aatagaaaag
     5101 agaaaataat atgattattt ctgaacaatc tgattttaga cgatatgctt ctatcaataa
     5161 acatttttca aaagtctgtg attttttaga aaatacaaat ttgacagatt tagttgatgg
     5221 aaaagttgat attgacgggg aaaatgtttt tgcaaattgt atgatctatc tagctgatgg
     5281 agtcccagga gatatttttg aaactcataa gaaatattta gatattcata ttgttgttga
     5341 aaatactgaa aaaatggcag taacttcccc agttcgtgcc cagtcacgtg taccttttag
     5401 cgaagaaaag gatattgctt tttacgatag caaagactat caaattgttg aattgcttcc
     5461 agggaatatg ttggtgactt ttgaagaaga tcttcaccaa ccaaagattc attgcaatga
     5521 tgagcctgtt aaaaaacttg ttattaaagt tttaaacgag gaaaaataaa atgaaaaaaa
     5581 atattaaaca atacgtaacc ttaggtactg cagtggtatt atcagcattt gttgctaact
     5641 cagttgcagc tcaggagact gaaacttctg aagtatcaac accagagttg gtgcaacctg
     5701 ttgcaccaac gactccgatt tcggaagtac aacctaaatc gggtaactct tcggaagtta
     5761 ctgtacaacc tagaacagtc gaaactactg ttaaggatcc atcttctgca acggaagaaa
     5821 ctcctgtctt agaaaaaaat aatgttactt taacaggggg cggagaaaat gttactaatg
     5881 agttaaagga taaatttact agcggtgact ttactgtagt gattaagtac aatcagtcta
     5941 gtgagaaagg cttacaagct ctgtttggaa tatctaattc taaacccggt caacaaaata
     6001 gttatgtaga tgtgttcctt agagacaatg gtgaattggg aatggaagcg cgtgatactt
     6061 cttccaataa aaatcaccta gtatccagac ctgcttcagt ttggggtaag tacaaacaag
     6121 aagctgtgac taacactgtt gcagtagtag cagattcagt caaaaaaaca tattctttat
     6181 atgcaaatgg tacaaaagta gtagaaaaga aagtggataa cttcttaaac atcaaggata
     6241 ttaaaggtat tgattactat atgcttgggg gagtgaaacg tgcaggaaaa acggcgtttg
     6301 gttttaacgg aacactagaa aatatcaaat tctttaatag tgcattggat gaagaaactg
     6361 ttaaaaagat gacaacaaac gctgttactg gacatttaat ttatacggct aatgatacaa
     6421 caggttctaa ctatttccgt attccagttc tgtatacttt tagcaatggt cgggtatttt
     6481 caagcattga cgctcgttac ggcggaactc atgatttttt gaataaaatt aatattgcta
     6541 caagttatag tgatgataat ggtaagacat ggactaaacc aaaattaaca ttggcattcg
     6601 atgattttgc gccagtacca ttagaatggc ctcgtgatgt tggtggacgt gacttacaaa
     6661 tcagcggtgg tgcaacctat attgactctg ttattgttga aaaaaataac aaacaagtac
     6721 tcatgtttgc ggatgtgatg cctgctggag taagttttag agaagctact agaaaagatt
     6781 caggttataa acaaattgat ggtaattatt accttaaatt aaagaaacaa ggtgatactg
     6841 attacaatta tactattcgt gagaatggta ctgtatacga cgatcgtacc aacagaccaa
     6901 ctgaattttc agtagataaa aatttcggta ttaaacaaaa tggtaattat ttgacagtag
     6961 agcaatattc ggtttcattt aaaaataata aaaagactga atatcgtaat gggactcacg
     7021 tccatatgaa tatcttctac aaagatgcat tgttcaaagt agtgccaacg aactatattg
     7081 catatatttc tagcaatgat catggcgaat cttggtctgc accaacttta ttacctccta
     7141 taatgggact taatcggaat gcgccttatt tgggtcctgg acgtggaatc attgaaagct
     7201 caactggacg tattcttatt ccgtcttaca ctggtaaaga gtctgcattc atttatagtg
     7261 acgataatgg agcatcttgg aaagttaaag ttgtgccact tccttctagt tggtcagcag
     7321 aagcacaatt tgtagaattg agtccaggag taattcaagc atacatgcgt acaaataatg
     7381 gtaaaattgc atatttaaca agtacagacg caggtactac ttggagtgca ccggaatatt
     7441 tgaaatttgt ttcaaatcca agttatggaa cacaattatc aatcatcaat tatagtcaac
     7501 tgattgatgg taaaaaggct gtcattttaa gtactccaaa ctccacaaat ggtcgtaaac
     7561 acggacaaat ttggattggt ctaattaatg atgataatac aattgattgg cgttatcatc
     7621 acgacgttga ttatagtaac tatggatact catattcaac attgacagag ttaccaaatc
     7681 atgaaattgg attgatgttt gaaaaatttg attcatggtc tcgtaatgaa cttcatatga
     7741 aaaatgttgt accatatata acatttaaga ttgaagatct gaaaaagaat taaagctgaa
     7801 atttgaaaat atataaaaag aggataaaaa ttatggtaaa ttacggtatt gttggagctg
     7861 gatattttgg agctgattta gctcgctcaa tgaacaaaat tgaagatgca aaagtggttg
     7921 cggtatttga cccaaatcat ggagaagaag ttgctcaaga gttgggatca gatgtttgtg
     7981 caagtttaga tgaacttgta gcacgtgaag atattgattg tgtgatcgta gcttcaccta
     8041 gctaccttca ccgtgaacca gttgtgaaag ctgctcaaca tggcaaacac gtattttgtg
     8101 aaaagccaat tgcattgtct tatgaagatt gtaaagccat ggttgacgca tgtaaagaaa
     8161 ataatgttat ctttatggct ggtcacatca tgaacttctt taacggtgta caccatgcta
     8221 aagaattgat tactcaaggt aaaatcggta aagttcttta ttgccatgcc gctcgtacag
     8281 gttgggaaga acaacaacca actgtatcat ggaagaaact tcgttctcaa tctggaggac
     8341 atttgtacca tcatattcat gaattagatt gcattcagtt tatcatggga ggacttcctg
     8401 aaaaagcgac aatggtagga ggcaatgtat atcataaagg tgaaaacttt ggtgatgaag
     8461 atgatatgct cattgtaaac ttagaatact ctgatgatcg ttatgctgtt ttggaatatg
     8521 gtaatgcttt ccgttggggt gaacactacg tcttgattca aggaactgaa ggagctatca
     8581 aacttgattt gttcaatact ggaggtactc ttcgtgttaa aggtgaagga gaatcacact
     8641 tcttagttca tgaaactcaa gaggaagatg atgaccgtac agctatctat accggtcgtg
     8701 gtatggatgg agcaattgcg tacggtaaac caggagtacg ttgcccatta tggttgcaaa
     8761 catgtattga taaagaaatg gaatatctac atgacatcat taaaggtgga gaaattacag
     8821 aagaatatga aaaacttctc aatggtgtag ctgctttaga atcaatcgct accgctgatg
     8881 catgtacttt atcagttaaa gaagatcgaa aagtaagtct ttcagaaatc acaaatgctt
     8941 aacttttgta aaacagaata gtaaattctt atcattatat aatttctaaa gttctgtgat
     9001 acaactcatt gaataaagaa atagagatgg gactgggata atgcccagtc ccatttttta
     9061 tcaaaaagta atgagatcaa aaatgtggga gtgatgaaat gaagattata gggatcgata
     9121 ttggcggaac aacaattaaa gcagatttat acaatgagtt tggaacgagt ttaaatcagt
     9181 tcaaagagat agaaacaatt attgactatg atttgggaac gaaccagata ttaaatcagg
     9241 tctgtgattt aattggtgag tatattttaa atcattcaat tgatggtgtt gggatttcca
     9301 ctgctggagt tgttaatgct aatacaggag agatcatcta tacaggctat acaataccag
     9361 ggtatatcgg agtaaacttt actttcgaaa tagaaaaacg ttttgggttg tctacttttg
     9421 ttgaaaatga tgttaattgt gctgcattag gtgaattgtg gaagggacaa gccaaagata
     9481 agaaaaatgt agtaatggtt actattggaa caggtatagg aggcagtatt attgtcaatg
     9541 gacaaattgt taacggattt aactatactg ctggtgaagt aggctatatt cctgtaggta
     9601 attcggattg gcaaagcaaa gcctcaacaa ccgcattgat tcatttatat caaaagaaaa
     9661 gcttgaaaac taatcaaact gggcgtactt tctttactga tttaagagct ggagataaag
     9721 tcgctaaaga aacttttgaa atttttgtag aaaatctaac aaaaggttta ttaacgatta
     9781 cttatctact taatccagaa attctcatat taggaggtgg gatcctggct aaaaaggata
     9841 ttttgttacc tgaaattcaa agttctttag ctaaaaatgc aatggataat aggtttttgc
     9901 ctaaaaatct tgtggcagct acattaggaa atgaagctgg tcgtatagga gctgtaaaaa
     9961 atttcttaga tagaatttct aataaatagt atgaaagata aggaggtgtc acaatgacta
    10021 actctgtatt ttcgacaatg caagatattg agaatgttgc aaccgatatt ataaaatcat
    10081 atgataatga gatttatact tataaagctg tttcccaaga agaattggaa aaactagaaa
    10141 aaagttatga tgaaaaaagt cacgaagaat tagtttcaat agaaagcaat ttagaaatga
    10201 aacaacagaa ccttattgat gaggttaata aaacaatcaa ggaaaattat gaaaagattc
    10261 agtatatttc atcaagtagg agaggagaat ttgtagaaaa aattattggt agggtggtag
    10321 aaaaatatgg ctattagtca gatgaaaaga atttctctac tattttctaa aagtagtctt
    10381 gatgatgttt taaaaactat tcaagaacta gagtcagtgc agttccgtga tttaaaggtt
    10441 caggataact ggtcagaagc tctagaaaaa gatgaggttg tatttccaac tattcaaatt
    10501 tctcatactt ctaattccaa tcatggggtt attgaaggaa atgatgcctt gatttatttg
    10561 atgaatcaac aacaatattt agaagcaact gtagagaaat tacaagaata cctaccgaaa
    10621 gaaaacacgt ttaaattatt acagcaacct ccgataacga cctcttatga agaattagaa
    10681 aaatttggta aagctaatgt tgctgagggt gttcttaaaa aagtgaatcg tcaaataaac
    10741 agagttcatg aattagaaag acacattcaa agtaataatg aggaaataga gagattaata
    10801 aaatgggaaa aattagaaat tattcctgcg catttagaac aatttttttt ctgtaaagga
    10861 aaagtcggaa caattccaag gactgtagat aatcgcttat acaatagttt tttagaaaac
    10921 aatattgaag ttcaagaaat attttctaat gatagagagt acggtgttgt tgttttctat
    10981 cagtccagtt gctctattga ttttgatgaa tacttatttg aaccatttga ttattctaga
    11041 aaggaattac cgaagcagcg agtagtagat ttggatcaag aaaacatgca gttaataact
    11101 gaaaaagaga atattatcgc atcgttgcaa gattcaaaga ataatttgat agatttacaa
    11161 tggcaaattg actatatttt atctatctat gctcgtcaaa tctctaagaa taaccttttg
    11221 agcactccgc atctagttgc actagaagga tggatagaag aaactcgt
//
LOCUS       DAVBCA010000061        11086 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.061, whole genome shotgun sequence.
ACCESSION   DAVBCA010000061 DAVBCA010000000
VERSION     DAVBCA010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11086)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11086)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11086
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.061"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(6..890)
                     /locus_tag="VQU19_001742"
     CDS             complement(6..890)
                     /locus_tag="VQU19_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HET2480954.1"
                     /translation="MRAKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVRDILSDMIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            complement(894..1280)
                     /locus_tag="VQU19_001743"
     CDS             complement(894..1280)
                     /locus_tag="VQU19_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HET2480955.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLISLMLEEQILTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            complement(1273..2616)
                     /locus_tag="VQU19_001744"
     CDS             complement(1273..2616)
                     /locus_tag="VQU19_001744"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HET2480956.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYEVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEGLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFATADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            complement(2698..3582)
                     /locus_tag="VQU19_001745"
     CDS             complement(2698..3582)
                     /locus_tag="VQU19_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2480957.1"
                     /translation="MIQVRNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGELVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHIEVLLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKDGQVIGTCTVDLSTNT
                     NYFYGLAISEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            complement(3594..4211)
                     /gene="cysE"
                     /locus_tag="VQU19_001746"
     CDS             complement(3594..4211)
                     /gene="cysE"
                     /locus_tag="VQU19_001746"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HET2480958.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFIW
                     KHGFKLLARMHSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            complement(4227..6440)
                     /gene="pnp"
                     /locus_tag="VQU19_001747"
     CDS             complement(4227..6440)
                     /gene="pnp"
                     /locus_tag="VQU19_001747"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HET2480959.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDDQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYADHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRLELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHHKDHKPKKEFTETPKDSE"
     gene            complement(7125..7991)
                     /gene="metF"
                     /locus_tag="VQU19_001748"
     CDS             complement(7125..7991)
                     /gene="metF"
                     /locus_tag="VQU19_001748"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HET2480960.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            complement(8055..10304)
                     /gene="metE"
                     /locus_tag="VQU19_001749"
     CDS             complement(8055..10304)
                     /gene="metE"
                     /locus_tag="VQU19_001749"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HET2480961.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVAAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVASDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            complement(10565..10831)
                     /locus_tag="VQU19_001750"
     CDS             complement(10565..10831)
                     /locus_tag="VQU19_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2480962.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGVSQPVIARMETGESSLQLDTVLKVLTSLGKTLAVVPLEQGKS"
     gene            complement(10915..11086)
                     /locus_tag="VQU19_001751"
                     /pseudo
     CDS             complement(10915..11086)
                     /locus_tag="VQU19_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
BASE COUNT         3095 a         2540 c         2194 g         3257 t
ORIGIN      
        1 cttctttaca aaccaactat agttgacaaa gaacctaaaa tcaattgata acacaaggtc
       61 aggtcggtca actctttcaa ctgaagccct gtcaactctt cccatttatc aatcttgtat
      121 tggagagaat tgcggtgcag atagagttgc tgggctgttt tagtgagaac agcactattt
      181 tcccaaagag agagaatgat ttcctgaatc tgatcttgat ccaaaatcat ctggtgtaga
      241 cattctttaa ttggcttcaa gtccacgagt ctttctccca tactccaaag atagagctga
      301 gaaaaagtat gaacaccttg gtgaccctga cgccaccatg tcttgaacaa atcccgctca
      361 gctttgatta agtctgatag ggcttgatgt cctgtctgag accaaacctg acccaacatg
      421 atagaaagac gaagtccaaa gtcatactca actgcttcaa tcatatcact taaaatatct
      481 cttacagaag tgtatttgtc ttgttgaagc acgaaaacat aatcctgagc tccgacctgt
      541 aacactgtct gacaattcgg aaaaagagtc cgcatcatat ctagccaaga agccagattt
      601 tcctgctgaa aataagaaag atggcaataa accaactgaa tctttttaaa aacttgcggt
      661 gcctgtccct tgccttcaac cagataggaa taccaagggt ttagcgaacg agcctgctcc
      721 tgctgggtca aaagggcaac caactgcttt tcacgctcgc tgagcccagc ttcctccagc
      781 aaaatccact gctgagaagc taaaggaagc gtgagatagc cctctttctc tactggttgg
      841 tctgaaatcc gagcctcagg aaaccagtct tgtagttctt ttgccctcat gttctagccc
      901 tccacttttt ggatgcacca tgaaaccaaa ctctcaagac gttccagatt ctcagtcata
      961 tggagatagc ccataactgc ttcaaatccc gtggacatac gataagtcac gacatctgca
     1021 tttttagcct ttgtgtgact attggtattg cggccacgtt tgtagatttc ttcttctttt
     1081 tccgttagga tctgctcctc caacatgaga gaaatcaggc gagcttgagc cttggctgac
     1141 acgtacttgg tcgcctcttg gtggagttta ttgggcttgg tcataccttt gaggatgagg
     1201 tggcggcgaa tatacataga atacaccgca tctccctcaa aggctagcgc aatcccgtta
     1261 atgagattga catcaatcac gtgtccacct cactccatcc ttggtatcaa ggagcttaat
     1321 tccttgagta accaattggt cacggatttg gtctgctgtc gcaaagtcac gattggcacg
     1381 cgcctcttgg cgtttttgaa tcaagtcttc aatctctgca tccaaaactt cctcaacaaa
     1441 gacaattcca aaaatttcta acatatctgc aagagcttgc ttgacacttg catcatagtt
     1501 ccctgagttg atccatttgg ccatttcaaa gacaactgtg ataccgttgg cagcattaaa
     1561 atcttcatcc atagctgcta caaacttatc tttaaagttt tgtaactctt gggcatccac
     1621 gtttcctgta aatggttgtt cgtaagtatt cttcagatac ttgagattgg tctcggcatc
     1681 gcgaactgcc ttttccgtga agttgatagg cttacggtag tgctgggtcg caaagaagaa
     1741 acgaagtact tgcccatcaa gagttttaag ggcatcgtgt accgtaatga agttacccaa
     1801 ggacttagac attttgacat tgtcgatatt gacaaagcca ttgtgcatcc agtagttagc
     1861 aaaagccttg cctgttttag cttcagattg ggcaatttca ttggtgtggt gtggaaactc
     1921 taggtcagct ccaccaccgt gaatatcaat ggtatcacct aaaatctctg tcgacatgac
     1981 tgaacactca atatgccaac ccggacgtcc aggtccccaa ggactatccc aagaaatctc
     2041 acctggtttg gaagatttcc atagagcaaa gtctacagga ttttccttac gagccgtttc
     2101 ttcatcggta cgacctgaag cacctagctc caaatcttcc aaggttttat tagccaattt
     2161 agcatagttg tgggattttt ctacacggaa atagacatcc ccttgactct cataggcaaa
     2221 gcctttctcg atcaagcctt ccacaaaacg gatgatgtct gccataaact ccactacacg
     2281 cggatggcga gtcgcaggtt tcacgcccaa ggccgtcaca tcctcacgaa aggcagcgat
     2341 gtacttatcc gcaacctcct gaggcgtgat gccttcttcc ctggcacggt tgataatctt
     2401 atcatccaca tccgtaaaat tggaaatata ggcaacctcg tacccacgat actcaaaata
     2461 gcgacgaatg gtatcaaaag ctaccgttga acgagcattc cctacatgaa tatagttgta
     2521 caccgttggc ccacaaacat acatcttgat cttgccgtcc tcaatcggga caaattctcg
     2581 caaatcacga gacatggtgt catagatttt aatcataaat cataatcaag aaagctgaaa
     2641 tccaagaaca attagtttca tcactaaaag ttcaagtaaa tttcagtccg aatatctcta
     2701 cacttcggaa tcccttgctc ctttctcatt cagataaacc acctgagtct gtttgacaaa
     2761 gccaattttt tcatacaaac gtttggcacc tacattgcta tcttccactg caatctgaaa
     2821 ttccttgtca ttttgctcaa ttagttggtt gacgagggat tttgctaagt agcttccata
     2881 gcctttccca cgttcaggtt ccgatattgc taaaccgtag aagtaattcg tattagtcga
     2941 taaatctacc gtgcaagtcc caataacctg accgtctttt aacaaaatat atagtcggct
     3001 ttctggatcc ttcagagctt cagcgacata tctatccaca acttctctcg attcatgttc
     3061 ctctgaaaat gcctgaaatt ttaattgact aatttgatcc tgatacgaac tatctgctaa
     3121 caaaacttca atatgggaaa catttgctaa cggataaggt cttctatcct tacctaacca
     3181 agtttctgtc tcttcatcct cgattagtcc ccagttactg gcaaagtcag gatgattctc
     3241 taaaaaaata cgttctgtct gaaaagtgac tgatcgaatg gggaaagaag ctgtttctct
     3301 ctcaaaacta gtaaacaatg cacgcgcaat cccctgacgg cgatgacctg gatgaaccag
     3361 tatcgtcact tctacatctt ggtcatctgc atagacagtt aataaaccaa caagttcgcc
     3421 tttttcataa taaaggaaaa aggcgggcat gtttgggtca aaattaagca tgttagagag
     3481 atagggatcg cgataggtac cgtcatagtt ttggcaacag ttaattactt ttttcgcctc
     3541 agatagctcc tcttggctta acttgtttct tacttgaatc atataggtat cctctacaaa
     3601 ccagacgatc tgtgactggc atctttagcc tgctcgagtt tattgacata atactctcgt
     3661 ttttcttcga cttcgtgaat gacaggctca tctttcttac catgaagacg gacaatcttg
     3721 gccggaatac cgacaaccgt cacatcacta ggtacatctg ctacgacaac tgctgcagca
     3781 ccgaccttgg cattttcacc aatttccaca ggtccgataa cttgggcatg ggctgatatg
     3841 agggctccct ttcgtacagt cggatggcgt ttgccacagt ctttccctgt tcccccaaga
     3901 gtcactccgt gatagagaag aacgcctttt tcaacaatcg ctgtctctcc aatcaccaga
     3961 ccagaaccat ggtcaataaa gacacctgaa tcaatctggg ctcctggatg aatctcaatc
     4021 tgagtccaaa agcgccaaaa ctgactgtgc atacgagcta agagtttgaa gccgtgcttc
     4081 cagataaaat gcgagagacg gtgggccgcc aaggccttga cacctggata agtcagcaaa
     4141 acctccaaag tggtgcgggc cgctggatca ttttctttta cgatatcaat ggtttcgcgc
     4201 caccacccca tacatttctc cttttcttat tctgaatctt ttggtgtttc tgtaaattct
     4261 ttcttaggtt tgtgatcctt gtgatgacgt gggcggtgag gacgctcaga cttttcacct
     4321 ttttcatcat gctcaggttt tggcggacga ggtagaagag ccttcataga ggcatcgata
     4381 cggccttttt catcaatctt gataacctta acatcaactt catccccgat ttctaccaaa
     4441 tcctctacac gattggtacg agtccaagcc atctcagaga tatgaacaag ggcatctgtc
     4501 ttatcaaaga ggttaacaaa ggcaccaaat ttctcgatac gaacgacttt agcacggtaa
     4561 acttcatcca ctttggcttc acgaaccaaa ccagcaataa tttctttggc acggttaata
     4621 gcatcttggt cactagagta gatagacaca tttccttctt cgtctatatc aatcttaaca
     4681 cctgtttcag cgataatctt gtcgatggtt tctccaccct taccgatgac aatcttaatc
     4741 ttgtccacat caatcttgat cgtatcaatt ttcggagcag ttggagccaa ttctagacga
     4801 acttctggaa tggttgcttc aatgacatca aggatttcaa aacgcgcttt cttggcttga
     4861 gcaagagcct ccgtcaagat ttctgcagta atcccttgaa tcttgatatc catttgaagg
     4921 gctgtaatcc catcacgagt acctgcaacc ttgaagtcca tatctccaaa gtgatcttcc
     4981 aaaccttgga tatctgtcaa tactgtgtag ttatttccat ctgagataag tcccatagca
     5041 ataccagcta ctggcgcctt gattggcaca ccaccagcca taagggcaag agttcccgca
     5101 cagatagaag cttgagatga agaaccgttt gattccaaaa cttctgctac tagacggata
     5161 gcgtatggga attcttccaa gcttggcaag acttgagcaa gagcacgctc accaagggca
     5221 ccgtgaccga tttcacgacg acctggcgca ccgtaacgac ctgtttcccc tacagaatat
     5281 tgagggaagt tatagtggtg cataaagcgt ttcttgtact ctggatccaa accatcaatg
     5341 atttgagttt ctcccatcgg agccaaggtc aagactgaaa gagcttgagt ttgcccacga
     5401 gtaaagagac ctgaaccatg tacacgagga aggaagtcaa caaccgcatc caaaggacgg
     5461 atttcatcga ccttacgacc atcaggacgc accttgtctt ctgtaattaa acgtcgcact
     5521 tctgcgtgtt ccatttgttc caagatttca gccacatcac gcataatacg gtcaaattct
     5581 tcgtggtccg catatttttc ttcgtaaacg gcagtcactt ggtctttcac tgcttgagtt
     5641 gcagcttcac gggccaattt ctcttctact tgaactgcct tttggaggtc actgttgtag
     5701 gctgcaatga tttcagcttg caattcagca tccacgtgaa gcaattccac ttctgctttt
     5761 tctttaccga cagcagcaac gatttcttct tggaaggcaa tcaattcttt gacagcttcg
     5821 tgccctttaa gaagcgcttc caacatgatt tcttctgaca attctttggc accagactct
     5881 accatgttga tagcgtgctt agttccagct actgtcaatt caagaagaga ttgctctgct
     5941 tgttcttgac ttgggttgat gatgatttgg tcatctacat atcccacttg taccccagca
     6001 attggtccgt caaatggaat atctgaaata gacagtgcca aagatgaacc aaacatagca
     6061 gccattggtg cagatgcatt ttcatcataa gaaagcactg tattgatgac ttggacttca
     6121 ttacggaaac cttccgcaaa cataggacga atcggacggt caatcaaacg cgctgtcaag
     6181 gtcgcatctg ttgaaggacg tccttcacgt ttcataaagc caccaggaaa cttcccagcc
     6241 gcatacattt tttcttcgta gttgacttgg agtgggaaaa aatccccagt tgccattttc
     6301 ttagacataa cggcagcagt caagacagtt gactcaccgt aacgtacgac aacagagcca
     6361 tttgcttgct tagcaacctg accagtctct acaattaact cacgacccgc aaaagtcgtt
     6421 tgaaacactt gttttgccat tttaatcccc tttggattga tgaaattata cgccttgcct
     6481 acaaagatca agataccaag gacgtcaaaa gcaaagtaaa aataggaaac tgacgaagtc
     6541 ttcgatgaag acaagacagt ttatcttttt tacacagctt ttcggccgtg ttcaattaca
     6601 caagatattt tggacggttc ggcttgccga acatttctgt agaaaaatag gaaggtgacg
     6661 tcgcactcga cgagtgctag gaagcttatc ttttttccta agaaatgaga ccaaaattca
     6721 agtcatcaag ataccaagcc gtcaagcaac tcaaaggaag ataggaaatc gaacgacgga
     6781 gcgactgctc ctaggcagat ttatcttttt ccacagagtt gtaggcgtgt tcagttttca
     6841 agatacatca ttagaaaggt ttaatattaa agtatctaaa cctttcacgc taatcgctat
     6901 cgggcgatta gctaaatgct ttactaactc tttcgtcaaa taacatcgat ttgactcact
     6961 cgtgtcgtta aatcttacag tttaaatgca ttgtattatt taataccttc atctttgtat
     7021 caagtacgta cagaatctat tttatcatat ttttcttaaa aagtgaggtc tttaccatta
     7081 aaaaggaacc attcccctca cctgagaaga atggtttgct tttattatcc tagagactgg
     7141 tgattaaaca aggcatgggt tgcttgatgg atgtattttg ctgtatcagc attattcatc
     7201 gtatagagat gcacaccggc aacatcctga gttaccaagt ccacgatttg gtccactgca
     7261 taggcaagtc ctgctgctct gagcgactca gggtcatgct catacttgtc taagatggct
     7321 ttaaatttgc gtggaagatg gatattctca caagtcttca agagtcggag agcctgattt
     7381 cgattcagaa ttggcataat tcctgcatga ataggaacat caatcccagc caagatacac
     7441 ttgtcctgaa aatcatagaa gcgctcattg tcaaagaaga gctgagttac gaggctcgaa
     7501 cagcctgcat ccactttctt cttaagattt tgaatatctg aaatctgatt tggcgaatct
     7561 ggatgccctt ctggatagca agctccaata atatcaaagt gaggggcttg ttccttgata
     7621 aactcaatca agtcggttgc atagcggaaa tccttttgtg gttctacgtc tggaataata
     7681 tccccacgaa gagccaagat tttctgaacc ccaactttgt ccaagtcagc aatagtttca
     7741 gcaaccttgt ccttagttag ataaatagct ggcaagtggg caatggtcgg aatcgccaag
     7801 tcattttgga taaagtcagc caaacgaacc gtcgtttcct tgatattaaa tttattattg
     7861 ctggcagtta cactgataaa atggggagcc aactcctgca tatcctgcaa ggctgaaata
     7921 atgttaccat tacccacggc tgggtttgga gggaacactt caaatgagag tgacggtgtt
     7981 tggcgtgaca tatgtaataa ccttttctag ttgatttctt tttgaacaac cactgtatgg
     8041 agagaaatcc aatcttacaa tttctcacgc gcagctttag ctgcttcaac aaggcggatc
     8101 aagctttctt ttgtttctgg gataccacgt gttttcaaac cacagtcagg gttgatccaa
     8161 actttcttgc ttggcacttt agcaaggatg gcttcgattg tgttgtcgat ttcgccttca
     8221 tttggtacac gaggtgagtg gatatcgtaa accccaggtc ccacttctgt ttggaagttt
     8281 ttcgctttga gttcgtccaa gatttcaagg tttgaacggc tggcttcaaa ggaaataacg
     8341 tctgcatcca tgttatcgat agctgggatg atatctgtaa attctgagta acacatgtga
     8401 gtgtggattt gtgtgtctga cgctactgtt gagtgtacca agcggaaggc aggaattgcc
     8461 cagtcaaggt aatcttcgta ccagtcacta cgacggagtg gcaatttttc acgaagagca
     8521 gcctcatcaa tttggatgat tttcacacca gcagcttcaa ggtcaagcac ttcatccttg
     8581 atagcaaggg cgatttgaag agtagaatcc ttgatagaga tgtcttcacg tgggaatgac
     8641 cagttaagga tggtaacagg tccagtcaac atacctttaa caggtttgtt tgtacgactt
     8701 tgtgcatagc tagaccattt aacagtgata gggttaagac gagtgacatc accccagatg
     8761 attggtggtt ttaccccacg cataccgtat gattgtaccc atccattttt agagaagagg
     8821 tatcctgaca agttttgacc gaagtactca accatgtcat tacgctcaaa ttcaccgtga
     8881 acaaggacat caaagtcaat atcttcttgc cacttgatcc attcgtcaat cgtttcagca
     8941 aggaaagcat cgtactcttt ttgagacaat tcacctttac ggtaagccaa acgtttggca
     9001 cgaacttctt ttgtttgagg gaatgaacca atcgttgttg ttggaagagc tggaagtttg
     9061 aaagcttctt cttggatagc ttcacgttct gcaaaggctg gcaaacgagt gtagtctgcg
     9121 tctgtcaagc cagcgatacg cgcacgaagt tcagcatttt caccaacacg ctcagtcgca
     9181 aagagttctt tgttggctgc aagagcttct gaaccttgac cattgcggat agcatccaag
     9241 tcacggattt catccaattt ttcaactgca aaggcaaagt ggttcaagag tgctggttca
     9301 aattcttcat tagcagttgt aaatggcaca tgaagaagtg agcaagagct tgtcaaaacg
     9361 atgttttcag ctggaatttg ctcaagaaca gccaagctct tttcgtagtt gttgcgccag
     9421 atgtttttac cattgacaat acctacatag agagtcttgt cagctgggaa gccaccttta
     9481 acgagttcaa gagttttctt accttcaaca aagtcaagac cgatagcatc tactggtaag
     9541 tttacaaggt cagcgtatac gtcacgaaca tcaccgaaat aagtttgaag caagacttca
     9601 agaccttttt tgtcagccaa gagtttgttg taaaggttca agaagagagc tttttcttca
     9661 gctgtcaagt cttttacaag agccgcttca tccaattgga tgcgagtcgc accaagttca
     9721 gccaatttag caaaaacttc ttggtaagca gccactaagc tatctacgaa gtcgtctgct
     9781 ttcacgcctt cttcaaagtc tgacaattga aggaaagtga agggacctac aagaacagga
     9841 cgagtgttca atccaagttc tttggcttct tggaactcat cgaaaatctt gtgaccagcc
     9901 aattttactt gagtgtcttt ttcaaattta ggaacgatgt agtggtagtt agtgttgaac
     9961 catttcttca ttggaagggc gcgaacgtcc cctttttctc cctggtaacc acgtcccaaa
    10021 gcgaagtagc gctcaaggtc agacaagtcc aagttttgaa cggatgcagg caccacgttg
    10081 aaaaggaaag ccgcatctag gaagttatca tagtgagaaa agtcatttga tggaatttca
    10141 gtgatgcctt tttctttgac aatgttccag tgtttagcac gcaagtcttt tgctgctgct
    10201 aaaagttctt cttctgagat ttcttttcta aagtattttt cagttgtaaa ttttaattca
    10261 cggaattcgc ccaaacgagg gaaaccgatg attgtagttg acatgatgtg tcctccaaaa
    10321 tttgttgttg aaactatctt aacagaaaag aaagcgtctg tataattgta aaaaattagg
    10381 gtttgatata gtttgaaact atatatctgt ttcggacaaa agaaaaagac ttgaagcaaa
    10441 cgtctcaaat cctttgtaat tcttacttta cagctatatt ccaattagaa tactaaaaca
    10501 tgttattagt aattcttata agtgactatg acctgttatt agaaaagact ataactgatt
    10561 ctagtcaact tttcccctgt tcaagtggaa cgactgctag tgtctttcct agactggtta
    10621 gaacttttaa gaccgtatcc aactgaagac tgctctctcc tgtttccatc ctagctatga
    10681 caggttgact cactccactg acttcttcca gctttttctg actgattcct tgttcatacc
    10741 tagcctcaat caactcgctc atgatagcca ctcgcatatc actttcaagg atttcctcct
    10801 tgctaaagag ctcagatgga catccttcca attactccca atagcactat tcttcatcac
    10861 ttaaccctct ttcttttacg tctatgtatt tttaaaagaa tgagcgaatt atgattcgat
    10921 agattgacca gcaggtttaa agttggtgct agcctgtttc ttaagcgctt ttccttttct
    10981 agggtaaagc agatcctgct tgcttaaccc caattttcca cgatgaatcc aatagtaaat
    11041 ggttgaaatt cccacgttaa cccctttagc catcaccatc atttca
//
LOCUS       DAVBCA010000062        10989 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.062, whole genome shotgun sequence.
ACCESSION   DAVBCA010000062 DAVBCA010000000
VERSION     DAVBCA010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10989)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10989)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10989
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.062"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            136..2316
                     /locus_tag="VQU19_001752"
     CDS             136..2316
                     /locus_tag="VQU19_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET2480963.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFTPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDTSQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKNLTEEVYSVADGQVVGLEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            2368..3183
                     /locus_tag="VQU19_001753"
     CDS             2368..3183
                     /locus_tag="VQU19_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HET2480964.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETLVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAMLNWK"
     gene            3323..4666
                     /locus_tag="VQU19_001754"
     CDS             3323..4666
                     /locus_tag="VQU19_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET2480965.1"
                     /translation="MSFTKFQFKNYIREALKELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLEIVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            5043..6233
                     /locus_tag="VQU19_001755"
     CDS             5043..6233
                     /locus_tag="VQU19_001755"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HET2480966.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            6786..7721
                     /locus_tag="VQU19_001756"
     CDS             6786..7721
                     /locus_tag="VQU19_001756"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HET2480967.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            7755..8792
                     /locus_tag="VQU19_001757"
     CDS             7755..8792
                     /locus_tag="VQU19_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HET2480968.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQVLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNSSPTTKLIIFAEGKLDSKRRLVKLLKRDAKVFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKANSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            8965..9570
                     /locus_tag="VQU19_001758"
     CDS             8965..9570
                     /locus_tag="VQU19_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HET2480969.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            9726..10256
                     /locus_tag="VQU19_001759"
     CDS             9726..10256
                     /locus_tag="VQU19_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HET2480970.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKEQRHFVIRQK"
     gene            10277..>10989
                     /gene="rlmN"
                     /locus_tag="VQU19_001760"
     CDS             10277..>10989
                     /gene="rlmN"
                     /locus_tag="VQU19_001760"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HET2480971.1"
                     /translation="MKPSIHSLAHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQGIVQESADGTVKYLFELPDGMLIETVLMCQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERISHIVVM
                     GIGEPFDNYNNVLNFFRTINDDKGMAIGARHITVSISGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFP"
BASE COUNT         3341 a         2017 c         2395 g         3236 t
ORIGIN      
        1 tagaaatttt ttagaaaaaa gtgtaatttt tttataaaag cctttacaaa aaaaattaaa
       61 gtggtataat taaatcatag aaggtgcaaa cgttttcgta aaacgtttgc ctaaataaaa
      121 ataaaggaga tttgaatgat gaaagataca ttcaaaaatg tcttgtcttt cgaattttgg
      181 caaaaattcg gtaaggcttt gatggtagtt atcgcggtta tgccggctgc tggtttgatg
      241 atttcaatcg gtaagtctat cgtgatgatt aacccaacct ttacaccact tgtcatcaca
      301 ggtggaattc ttgagcaaat cggttggggg gttatcggta accttcacat tttgtttgcc
      361 ctagccattg gaggaagctg ggctaaagaa cgtgctggtg gtgctttcgc cgctggtctt
      421 gccttcatct tgattaaccg tatcactggt acaatttttg gtgtatcagg cgatatgttg
      481 aaaaatccag atgctatggt aactactttc tttggtggtt caatcaaagt tgctgattac
      541 tttatcagtg ttcttgaagc tccagccttg aacatggggg tattcgtagg gattatctca
      601 ggttttgtag gggcaactgc ttacaacaaa tactacaact tccgtaaact tcctgatgca
      661 ctttcattct tcaacgggaa acgtttcgta ccatttgtag ttattcttcg ttcagcaatc
      721 gctgcaattc tacttgctgc tttctggcca gtagttcaaa caggtatcaa taacttcggt
      781 atctggattg ccaactcaca agaaactgct ccaattcttg caccattctt gtatggtact
      841 ttggaacgtt tgctcttgcc atttggtctt caccacatgt tgactatccc aatgaactac
      901 acagctcttg gtggtactta tgacatttta actggtgcag ctaaaggtac tcaagtattc
      961 ggtcaagacc cactatggct tgcatgggta acagaccttg taaaccttaa aggtactgat
     1021 actagtcaat atcaacactt gttagataca gtacatccag ctcgtttcaa agttggacaa
     1081 atgatcggtt cattcggtat cttgatgggt gtgattgttg ctatctaccg taatgttgat
     1141 gctgacaaga aacataaata caaaggtatg atgattgcaa cagctcttgc aacattcttg
     1201 acaggggtta ctgaaccaat cgaatacatg ttcatgttca tcgcaacacc tatgtatctt
     1261 gtttactcac ttgttcaagg tgctgccttc gctatggctg acgtcgtaaa cctacgtatg
     1321 cactcattcg gttcaatcga gttcttgact cgtacaccta ttgcaatcag tgctggtatt
     1381 ggtatggata tcgttaactt cgtttgggta actgttctct ttgctgtaat catgtacttt
     1441 atcgcaaact tcatgattca aaaattcaac tacgcaactc cagggcgcaa cggaaactac
     1501 gaaactgctg aaggttcaga agaaaccagc agcgaagtga aagttgcagc aggctctcaa
     1561 gctgtaaaca ttatcaacct tcttggtgga cgtgtaaaca tcgttgatgt tgatgcatgt
     1621 atgactcgtc ttcgtgtaac tgttaaagat gcagataaag taggaaatgc agagcaatgg
     1681 aaagcagaag gagctatggg tcttgtgatg aaaggacaag gggttcaagc tatctacggt
     1741 ccaaaagctg acattttgaa atctgatatc caagatatcc ttgattcagg tgaaatcatt
     1801 cctgaaactc ttccaagcca aatgactgaa gcacaacaaa acactgttca cttcaaaaat
     1861 cttactgagg aagtttactc agtagcagac ggtcaagttg ttggtttgga acaagtaaag
     1921 gatccagtat ttgctcaaaa aatgatgggt gatggatttg cagtagaacc tgcaaatgga
     1981 aacattgtat ctccagtttc aggtactgtg tcaagcatct tcccaacaaa acatgctttt
     2041 ggtattgtga cggaagcagg tcttgaagta ttggttcaca ttggtttgga cacagtaagt
     2101 cttgaaggta aaccatttac agttcatgtt gctgaaggac aaaaagttgc agcaggagat
     2161 ctccttgtca cagctgactt ggatgctatc cgtgcagcag gacgtgaaac ttcaacagta
     2221 gttgtcttca caaatggtga tgcaattaaa tcagttaaat tagaaaaaac aggttctctt
     2281 gcagctaaaa cagcagttgc taaagtagaa ttgtaatata cttgaggttg gaagctgtat
     2341 tccaacctct tattttggga gaaaagaatg aaatttttaa cactcaatac tcacagttgg
     2401 atggagaaag aagcagagga aaaattccag attttgcttg aagatattct tgaaaaggac
     2461 tatgatttga tttgtttcca agaaatcaat caggagatga cctcgtcaga ggtggaggtt
     2521 aatgaccttt atcaagcttt gccagcagct gagcctattc accaagacca ttatgttaga
     2581 ctcttggttg aaaagttgtt agagcaaggg aaaaattact actggacctg ggcttataac
     2641 catatcggct atgaccgcta ccacgaaggt gtggctatct tgtctaaaac acctattgaa
     2701 gccagagaaa ttttggtttc agatgtggat gatccaacag actatcatac tcgccgtgtt
     2761 gccctagctg aaactttagt cgatggcaag gagctagcag ttgccagtgt tcatctctct
     2821 tggtgggata aaggtttcca agaagaatgg gcacgatttg aggctgtctt gaaaaaattg
     2881 aacaagccac ttttactagc tggagatttt aacaacccag caggtcagga aggttaccaa
     2941 gctattttag ctagtccatt aggcttacaa gacgcatttg aagttgctca agagaaaagt
     3001 ggtagctata ctgttccgcc tgaaattgat ggctggaaag ggaacactga accccttcga
     3061 atcgattatg tctttactac caaagagtta gcggtggaaa atttacatgt cgtatttgat
     3121 ggtaacaaga gtccacaagt gagtgatcac tatggcttga atgctatgtt aaactggaaa
     3181 taataactga aaagaggttg gaactataaa attccagcct tttcttacta gagaagctac
     3241 tggaaatagc ctaaataagt gagactactg taatggaata aaatatggta taattgataa
     3301 gatagataga atcgaggatg ttatgtcatt tacgaaattt caatttaaaa actatattag
     3361 agaagccttg aaggagttaa aatttacaac tccaacagag gtgcaagata agttgattcc
     3421 tattgttttg gcaggtcgtg acctagtagg agaatcaaaa acaggttcag gtaagactca
     3481 tactttcttg ttaccgattt tccagcaatt agatgaagct agcgatagtg tacaagcagt
     3541 gattactgca ccgagtcgtg agttggctac tcaaatttac caagtagcgc gtcagatttc
     3601 agctcactca gatgtcgaag ttcgtgtggt taattatgtg ggtggtacgg ataaggctcg
     3661 ccagattgag aaattggcaa gcaatcagcc tcatattgtt attggaacac caggccgtat
     3721 ctacgacttg gttaaatctg gtgatttagc tattcataaa gccaagacat ttgttgttga
     3781 tgaagcagat atgaccttgg atatgggatt cttggaaatt gttgataaga ttgctggcag
     3841 tcttccaaaa gacttgcaat tcatggtctt ctcagcgact atcccacaaa aactgcaacc
     3901 attcttgaaa aaatacttat caaatcctgt tatggagaaa attaagacta aaacggttat
     3961 ttctgacacc attgataatt ggttgatttc gaccaaggga catgataaga atgctcaaat
     4021 ttaccaattg actcagttga tgcagccgta tttggcaatg atttttgtta acactaaaac
     4081 gcgtgctgat gaattgcatt catatctgac tgctcaaggc ttgaaggttg caaaaatcca
     4141 tggagatatt gcccctcgtg aacgcaagcg aatcatgaat caggtgcaaa atctggattt
     4201 tgagtatatt gtcgcaacag atttagcagc gcgtgggatt gacattgaag gtgtcagcca
     4261 tgtcatcaat gatgccattc cgcaagactt atcttttttt gttcaccgtg ttggtcgtac
     4321 tggacgaaat ggcctaccag gtacagctat taccctttat cagccaagtg atgactcgga
     4381 tatccgtgag ttggagaaat tgggaatcaa gtttagtcct aagatggtca aagatgggga
     4441 atttcaagat acctatgacc gtgatcgtcg tgccaaccgt gagaaaaaac aagataaact
     4501 tgatatcgaa atgattggtt tggttaaaaa gaaaaagaaa aaagtcaaac cgggttataa
     4561 gaagaaaatt caatgggcgg ttgatgaaaa gcgccgtaaa actaagcgtg ctgaaaatcg
     4621 cgctcgcggt cgtgcagagc gtaaagctaa acgccaaaca ttttaataga aattgttgga
     4681 gtactgagct ccaacttttt tatttatgag aacgaactat ctaaaccgaa acactacatt
     4741 aaagactgca aattgcgatt aaaaatggta taatgataaa gttatatagt cccgataaga
     4801 tggtaggtat ttattacgaa gagttttcct atcagtagtt tgcaattcgc aaagaatgac
     4861 ggcttcgagg tcgctcgtct ttctacggtt gccgccatac tgcggtcacc ctatgcgcct
     4921 tactagcttc agaaataaaa aagtatcgtt tttatttctg aagctagtaa ctcttagata
     4981 atggaaattc ctatcagtac tttgtaactc tataacaata ttttttaagg ggggacattt
     5041 ttatgtcaga acgtaaatta ttcacgtctg aatctgtatc tgaggggcat ccggataaga
     5101 ttgcagacca aatttcagat gcgattttgg atgctatttt agcaaaggat ccagaggcgc
     5161 acgttgctgc tgaaacagct gtatatactg gttctgtcca cgtttttggt gaaatttcta
     5221 caaatgccta tgtggatatt aaccgtgtgg ttcgtgatac cattgcagag attggttata
     5281 ccaatacaga atatggattt tctgctgaga cggtgggagt acacccatct ttggtggaac
     5341 aatctcctga catcgctcaa ggtgttaacg aagccttgga ggttcgtgga aatgctgatc
     5401 aagatccact ggacttgatt ggagcaggtg accaagggct catgtttgga tttgcagtag
     5461 atgaaacaga agagctcatg ccattgccaa ttgcactcag tcataaattg gttcgtcgtc
     5521 tggcagaact tcgtaagtct ggagaaatta gctatctccg tccagatgca aaatcacaag
     5581 ttacagttga gtacgatgaa aatgaccgtc cggtacgtgt agatacagtc gttatttcta
     5641 ctcagcatga tccagaggcc actaatgaac aaatccatca agatgtgatt gacaaggtca
     5701 tcaaagaagt tattccatct tcttatcttg atgataagac aaaattcttt atcaatccga
     5761 caggtcgttt tgtaatcggt ggtcctcaag gggactcagg tttgactggt cgtaagatta
     5821 ttgtagatac ttatggtggc tactctcgtc atggtggtgg tgccttctct ggtaaagatg
     5881 cgactaaggt ggatcgttca gcctcttatg cggctcgcta tattgccaag aatatcgttg
     5941 cagcaggcct tgctaagaag gcagaagtgc agttggccta tgctatcggt gttgcgcaac
     6001 ctgtttctgt tcgtatcgat actttcggta caggaacagt agctgaaagt caacttgaaa
     6061 aagcggctcg tcaaatcttt gaccttcgcc ctgcagggat tatccaaatg ctggacctca
     6121 agcgtccaat ttaccgtcaa acatcggctt acggtcacat gggacgtaca gatattgatc
     6181 ttccatggga acgtttggat aaggtagatg ctttgaaaga agcagtaaaa taagatttta
     6241 agaggggaac gtcctctctt ttttatagtt tttaactata ctgggatact gttctgaaaa
     6301 tccattttgc gaaagtagag atttacatgt ataatggatt gaaactagaa tagtacacct
     6361 caacttctaa aacattgtta gaaatcgatt tgactgtcct gatcgatttc tcctgttctt
     6421 gtttcatttt actatatttc tttaaaaatg ataaaggttg agatttctcc tcgtaataga
     6481 taatcatggg gatatttcaa tccaaagttt tattcgttat cacttgacta ttgcaaggtt
     6541 ttctagagca acagagtcat ggaatggact catggttgag atttctcctt gttgcttgga
     6601 cttcattcaa aagtctgtta cccaagcctt gttcaaactt ccaatacact agctgtttcc
     6661 atagcatgac ttctgtacta gactttcttt tccgaataaa tagatagaac cacagaatct
     6721 agtaaaccta gaattaaaat tatggtataa tattagcaat aaaagaaatc tggaggatta
     6781 gaatcatggt atcaacgaaa acacaaattg ctggttttga gtttgacaat tgcttgatga
     6841 atgcagcagg tgtggcttgt atgacgatag aggagttaga agaggtcaaa aactcagcgg
     6901 caggaacctt tgttactaag acagcgacct tggacttccg tcaggggaat cctgagccac
     6961 gctaccaaga tgttccactt ggttccatca actctatggg cttgccaaat aatggcttag
     7021 actattattt ggattatctt ttagatttgc aggaaaaaga gtcgaaccga actttcttct
     7081 tatctctggt cggcatgtct ccagaggaaa cccatactat tttgaaaaaa gtccaagaga
     7141 gtgattttcg tggtctgact gagctaaatc tttcctgtcc aaatgttcca ggtaaacctc
     7201 agattgccta tgattttgag acaacagacc ggattttggc agaagtgttt gcttacttca
     7261 ccaaacctct tggaattaaa ttgccacctt attttgatat tgttcacttt gaccaagcgg
     7321 cagctatttt caacaaatat ccgctcaagt ttgtcaactg tgttaactct atcggaaacg
     7381 gcctctatat agaagacgaa tctgtcgtta ttcggcctaa gaatggtttt ggtggaattg
     7441 gtggagaata catcaaaccg actgctctag ccaatgttca cgccttttat caacgtttaa
     7501 atcctcaaat ccaaattatc ggaacaggtg gcgttctgac tggtcgagat gcctttgaac
     7561 acatcctctg tggagcaagt atggtgcagg tgggaacgac ccttcacaaa gaaggcgtca
     7621 gtgcttttga ccgcattacc aatgaactga aagcaatcat ggtggaaaaa ggctacgaga
     7681 gcttagaaga tttccgtggg aaattgcgct atattgacta aattaaatcg aaaaatctga
     7741 agaaaggaga gacgatgcta gccattgaag aaagtcagaa gttgacttta tcaaatttac
     7801 cgagcctgag cctatttaca gggacagatc agggtcagtt tgaagtgatg aagagtcaag
     7861 tgttgaaaca gattgggtat gattctgctg acctcaactt tgcctacttt gatatgaaag
     7921 aagtagttta caaggatgtg gaactggagt tggtcagcct tcctttcttt gcggatgaga
     7981 aaatcgtgat attagattat tttatggata tcacgactgc taagaaacgc tttttgacag
     8041 atgatgagct taagtcattt gaggaatacc ttgacaattc ttctccaaca accaagttga
     8101 taatctttgc agaaggaaag ctggatagca aaagacggtt agtcaaatta cttaagcgtg
     8161 atgccaaggt cttcgatgca gtagaagtaa aagaacaaga attgcgccag tatttccaaa
     8221 agtggagtca gaaacaaggt ctgcagttta ccaatcattc ttttgaaaat ctcctcatca
     8281 agtcggggtt tcaatttagc gaaatccaga aaaatcttct ctttttacag tcctataagg
     8341 cgaattctgt tattgaggaa gaggatattg ttaacgcaat tcccaagacc ttgcaggaca
     8401 atatttttga tttaactcag tttattctga ctaaaaagat ggatcaggcg cgcgatttgg
     8461 tgagagactt gaccttgcaa ggggaagatg aaatcaaact gattgcagtc atgctgggac
     8521 aatttcggac ttttactcag gtgaagattt tggcggagtc tggccaaaca gaatcgcaga
     8581 ttgcaagtag tttaggtagt tatctgggac gtaacccaaa tccttatcaa atcaagtttg
     8641 cattaagaga ttcgagagga ctttctttga gctttctgaa gcaagctatt tcctatttga
     8701 ttgagacaga ctatcagatt aagacaggtc tttatgaaaa aggtttcctt tttgaaaagg
     8761 cactcttaca gattgctagt caggtcaatt gacatttgtt gaaactacaa cccgcgtcag
     8821 gattatcttg tcgtgggttt cttgctgatt tgcttatttt attagaaagt atgtcagtga
     8881 tttccttatc tataagcaaa aaacttgaaa aaagtgaatg tttgcgttat cattttcata
     8941 tagaaagaaa aagaggtatt acagatggct attatcttac cagaacttcc atatgcatac
     9001 gacgctttgg aaccatacat cgatgcggaa acaatgcatt tgcaccatga caaacaccat
     9061 caaacttatg tcaacaatgc caatgcagct ttagaaaaac accctgaaat cggtgaagac
     9121 cttgaagcct tgcttgctga tgtagaatct atcccagctg atatccgtca agcacttatc
     9181 aacaatggtg gcggacactt gaaccacgct cttttctggg aattgatgac tcccgagaaa
     9241 acagctcctt cagcagaact ggcagcagca atcgatgcaa catttggttc atttgaagaa
     9301 ttccaagcag ccttcactgc agcagcaaca actcgttttg gttcaggttg ggcatggttg
     9361 gttgtcaaca aagaagggaa acttgaagtg acttcaacag caaaccaaga cacaccaatc
     9421 tcagaaggta aaaaaccaat cttgggcttg gacgtttggg aacatgctta ctacgtgaaa
     9481 taccgcaacg tgcgtcctga ctacatcaaa gctttctttt cagtaatcaa ctggaataaa
     9541 gtagatgaat tgtacgcagc tgctaaataa tgatagttgg agggaagaat tgttcttctc
     9601 tttttaggtt ataagattct ggtctgacaa aatcgtcaga cttttttcat ttttatgaga
     9661 aacgtgctaa ctgctagaaa ttatggtaga ataaagtatt aagtaatcgt ggaaaaagga
     9721 tatctatgcg aaaagaaatt gcacctgaat tatacaacta taacaagttt cctggtccgg
     9781 agttccattt acacggggat aaggtcgaaa cggaagggat agctttttcc ttggttgaaa
     9841 atatcaagga tgcctttgat gtgacgactt ttaatcagcg tttttcagaa gtcttaacca
     9901 agtttgatta tatcgtgggg gactggagca acgaacagct tcgcctacga ggtttttaca
     9961 aggatgaccg aacagaagaa aaacttgaaa aaatcagtcg tttacaagac taccttttag
    10021 agtattgtag ttatggttgt gcctattttg tcttagaaaa tgaagcccct aagcgagcat
    10081 catttgacaa gaaaatgcgt aagacggaag aagaaacacc ttctagaaaa ggaaagaaac
    10141 cgactcaaac taaacgaaag tcgaatgcag ataagaaaaa tagacgtcgt cagaaagacc
    10201 agcattctca gaaagaggac aaggaacaac gtcattttgt cattcgtcag aagtgagtag
    10261 agaataagga gaagaaatga aaccctcaat tcatagtttg gcacatcaaa ccatgcagga
    10321 atgggtattg gagcagggag aaaagaaatt ccgtgcagat caaatctggg aatggctcta
    10381 ccgtaaacgt gtgcagtcat ttgaagaaat gaccaacctt tccaaggatt tgattgctaa
    10441 gctcaatgac cagtttgtgg tcaatccctt gaaacaaggt attgtgcaag agtctgctga
    10501 tggtacagtc aaatatctct ttgaattgcc tgacggtatg ttaattgaga ctgtactcat
    10561 gtgtcaacac tatggtttat ctgtctgtgt gaccactcag gtcggctgta atatcggttg
    10621 taccttctgt gcctctggtt tgattaagaa gcagcgtgac ctcaataacg gtgaaatcgt
    10681 agcgcaaatc atgctggttc agaaatactt tgatgagcgt ggtcaggatg aacgcatcag
    10741 ccatatcgtt gtcatgggaa tcggtgagcc ctttgataat tacaacaatg tcttgaattt
    10801 ctttcgtact atcaatgatg ataaaggaat ggctatcggt gctcgtcaca tcacggtttc
    10861 aatctcaggt ttggctcata aaattcgtga ctttgctgat gaaggggttc aggtcaatct
    10921 tgccgtgtct cttcacgcac ccaacaatga acttcgttca agtatcatga agattaaccg
    10981 tgcctttcc
//
LOCUS       DAVBCA010000063        10815 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.063, whole genome shotgun sequence.
ACCESSION   DAVBCA010000063 DAVBCA010000000
VERSION     DAVBCA010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10815)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10815)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10815
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.063"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            159..449
                     /locus_tag="VQU19_001761"
     CDS             159..449
                     /locus_tag="VQU19_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480972.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETTEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEYPELYAVAQTSGEIPEKNAKNCVRLSQLSLNKR"
     gene            473..1189
                     /locus_tag="VQU19_001762"
     CDS             473..1189
                     /locus_tag="VQU19_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET2480973.1"
                     /translation="MKKYFIGGLGSNAYHSKDFLQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSIGGDLARYFASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIISDLDVLTSKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNEATWREEALKELPDYFDTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
     gene            complement(1318..2133)
                     /locus_tag="VQU19_001763"
     CDS             complement(1318..2133)
                     /locus_tag="VQU19_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HET2480974.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWITAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(2130..3035)
                     /locus_tag="VQU19_001764"
     CDS             complement(2130..3035)
                     /locus_tag="VQU19_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HET2480975.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGMLFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMILAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLVYSLLIGVIL"
     gene            3433..5562
                     /locus_tag="VQU19_001765"
     CDS             3433..5562
                     /locus_tag="VQU19_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HET2480976.1"
                     /translation="MDKKYEKISQDLGVMLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRAQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYTAVKELFKRL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVSVGD
                     LVTVWVKKIDTEREKVNLSLLAPNETD"
     gene            5549..5998
                     /locus_tag="VQU19_001766"
     CDS             5549..5998
                     /locus_tag="VQU19_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HET2480977.1"
                     /translation="MKLTDYVKQVSLEDFGRAFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQKLGMEVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPLKLYRCQSCQQRYQRKRRIDTKRYRCGLCRGKLLLINQPED"
     gene            6057..6329
                     /locus_tag="VQU19_001767"
     CDS             6057..6329
                     /locus_tag="VQU19_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HET2480978.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(6683..6874)
                     /locus_tag="VQU19_001768"
     CDS             complement(6683..6874)
                     /locus_tag="VQU19_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480979.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            7302..8060
                     /locus_tag="VQU19_001769"
     CDS             7302..8060
                     /locus_tag="VQU19_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2480980.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFDEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            8062..10050
                     /locus_tag="VQU19_001770"
     CDS             8062..10050
                     /locus_tag="VQU19_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2480981.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTVTYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVVFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQTKVVITVLV
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSSESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYSVKEKEVLRYSNFGIANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNEGVKEQKALTLNDHQFSVKEEFTKDFIVNHVPNQF
                     NILTADYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVNASEAEQLKVAEEYEKYLQKF
                     NAQLNTEGNYVYGSTLADASAQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFLHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(10092..10736)
                     /locus_tag="VQU19_001771"
     CDS             complement(10092..10736)
                     /locus_tag="VQU19_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HET2480982.1"
                     /translation="MLRAGVLDANDGIISIAGVVIGVASATTNIWIIFLSGFAAILAG
                     AFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLYAAYIQNEEFKTSAQLL
                     TNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSDYR
                     IPATVLIVGVALLLTGYTSARLGKAPTKTAMIRNLAIGLLTMGVTFLLEQLFSI"
BASE COUNT         3347 a         2024 c         2257 g         3187 t
ORIGIN      
        1 ttgcttcata attcatagaa ctactatacc atattttgtt tcgcaggaag tctaatgcta
       61 aaatcttatc agtgagaaga tttcttaaag tttattcttt gtagtttcat ctgtattagt
      121 acataattta acttagagaa aataggagga ctaatcgaat ggaattaaaa gattttacag
      181 aaaaagaaca ggaaatgatt aagaaaaggc ttacaatgtc taatattagt gacaaagaaa
      241 ctactgagaa gattctggcg ctagtcccac aagacttgat taagcgaatc ccgttttttg
      301 tcagaaaaca tgctacaaca cgtacgatta aacgtatttc aattgaatac cctgaactct
      361 acgctgtagc tcaaacaagt ggtgagattc cagaaaaaaa cgcgaagaat tgcgtcagat
      421 tatcacaact atctttgaac aaaagatgaa taagcatagt attaagtaga gaatgaaaaa
      481 atattttatt ggcggtttgg gaagcaatgc ctatcatagc aaggattttc ttcaagaact
      541 agattcgcag gtctattttc taaatccata tgaaaagcat cttcgagatg aaacagaatt
      601 gaaatcatgg tttaaaaatg agattgtaga ggaagaatct atctgtctga taggtcattc
      661 tattggaggc gatttagctc gttatttcgc atcggaattt gaagaagtaa agaaactgat
      721 tcttttggat ggtggctatc tagatttaga taagatttta cctttggata cagagttaga
      781 ggaaactaaa aattatatca aatctcaaat tatttcggac ttagatgttc ttacttctaa
      841 agaaaaatct gaagcaaagc attggtcaga aaatatggag aaagctgtaa gacagtccta
      901 tcactggaat gttgagtata atagatatga gttggctata aattatgaaa atatagaagc
      961 gatactccgc ctacggagaa aaatacaagc ttttaagaga gaagtgggag ataccttgtt
     1021 tattagtcct cgctatccta atgaagctac atggagagag gaagccctaa aagaattgcc
     1081 agactatttt gatactattt ttttagaaaa ctttggccat gagctttata ctcaagcacc
     1141 taaagaaatc gctagtctaa tgaatgagtg gctcgcttat tttctatgag ctacttgtat
     1201 tgctggaaat ggtataagat gaaaatctac aagtcactaa ttttcatata acaaaaaacg
     1261 aacaggctct ttttctgtta ttcagaagag aacttgttcg tttttatctt gattttctta
     1321 aaaagctcta tatacatagg gattttctgg tttatcgact ttggtaaagc tgtcgatttc
     1381 caaggttgga aggttttgtt tgagttcttt atggtagtga ttgaccagtt ttcctttggc
     1441 tgttatccaa gtgttgtttt catactgccg ggtattgccc ttggtcagca atccatagac
     1501 accagaatct gcgatacagt ggataatgcc gaatcggaac agaaattgac tattggcatg
     1561 actggggtcg ttatagacaa agcctgtaaa ctggattgtc ttgccctcaa actcatctgg
     1621 atagtcgtag atagcctcca tgacttccat atagttttca ttagtgatct gaatactatc
     1681 ttgggataag tatttatccg ccgccgttcg catttccttt tcataggctg attttgaaaa
     1741 ataagaactg gtatctggtt tcaaatattg gcttgtcgtc ccttcgcttg tctgaatggc
     1801 tagatctgtt ccttccgata gggggaaatg ataaccttta gcagaaacgg tctgagaatc
     1861 caagctaaca gttgggaaag ttaagccgat gacaagtgga atagccagaa gagaaatact
     1921 cgtcatcttg gccaatcggc tgttcagatg actgtgggtt ttgacttgct tcatccagat
     1981 atacaattga acaattgcca agataaagga aagcaccatg gagatatagg ccagatagga
     2041 atagtgcatg ttgatgtact ggtttagttt gcccgacaga tggaggtaaa tagtcagttc
     2101 aaaatagcca gctaaaacta aaaatcgaat cataggatga ctccaatcaa gagagaatag
     2161 actaagacga caagagttac aatcgttatg aagtgactga taaatcgtgc tttcaagtaa
     2221 tttttcatca tgagaatatt tttgatatcc agcattggac caatgacgag aaaggccaga
     2281 actggtgcca aaccgaaact cgagagaaga gaagcaccta taaaggcatc cgcctcacta
     2341 cagagcgaaa gaagaaaggc caaaatcatc aagagcagga tggcaaaaag aggagtcgca
     2401 ctgatagagg tcagaatccg agtcggaacg tagacctgta ttatagaagc aaagaggcag
     2461 ccaaatacca aataacgccc cgtatcaaaa aattcatcaa tggcctgcac aaagacttga
     2521 aaaacttttt ttgcagaact caagtaagaa aaatcatgct catgacaagc cagacgattt
     2581 tctttctgaa tcggttcttg ccagaaaaat cctagaaaaa ttcctagtat tacagccaca
     2641 agaatggaac ccagagctcg taatagggcg acatggaagg agttgccaaa ggcagaatag
     2701 gtcgcaaaaa gaacaatggg attgataaca ggtgctgtca caagaaaagg aacggctgtg
     2761 taactgggaa cctttttttc cagaaaacga ttgatgatgg ggacgattcc acattcacaa
     2821 gaagggaaaa gcataccgac aaaggtccca aaaaagattc tcccccaacg atttcgaggg
     2881 agaaaatgat aaaccttgtc aggtgtgata taaacttcaa tcagccctga gacaatgctt
     2941 cctattagaa cgaagggaag ggcttcaatg ataatggaga gaaaaatggc tccagtttga
     3001 agtacactag atgggagttg ttgaaaagca gtcatctagt ttttcttttc tgctttggct
     3061 tttttctctt tgtcatcagg gaaagtaact tgtttcaaat cagggagttt agcaaactct
     3121 tcaaacatct tgtccaagtc gtctcgtttt gtaaatttta cagccatagg tgtacctcga
     3181 ttctaaagtc tacctctatt atactattat tttgcggaaa agggagtttt ttaatttgtt
     3241 ttcgatagtt gatacacttc gaaaatctct tcaaaccacg tcagcttcgc cttaccgtat
     3301 atatgtgact tatccacaac ctcaaaacag tattttgagc agcctgcggc tagcttccta
     3361 gtttgctttt tgattttcat tgagtatgaa aaggattgga gaaagccttc cagcttgtgg
     3421 tataatagat ttatggataa aaaatatgaa aaaatctctc aggatttggg agtgatgtta
     3481 aagcaaattg ataccgttct aagtttgaca gctgaagggg cgactattcc ctttatcgcg
     3541 cgttatcgca aggacatgac tggtagtctg gatgaggtgg cgattaaggc tattattgat
     3601 ttggataaaa gtctgacaaa tctcaatgac cgtaaggaag ctgtcttagc taagattcaa
     3661 gaacaaggta agttgaccaa ggaattggaa gaagctatct tagttgccga aaaattagca
     3721 gacgttgaag aactctatct tccttataag gaaaagcgtc gtaccaaggc aaccattgcc
     3781 cgtgaagctg gactctttcc tcttgctcgt ttgattttgc agaatatagt tgacttagag
     3841 aaagaagctg aaaagttcgt ctgtgaagga tttgcgactg gcaaggaagc cttgaccggt
     3901 gcagttgata ttttggtcga agccttatcg gaagatgtga ccttgcgttc tatgacttat
     3961 caggaagtgc tgagacactc taaacttact tctcaagcca aggatgaaag tcttgatgaa
     4021 aagcaggttt ttcagattta ttatgatttt tcagagacag ttggaactat gcaaggctat
     4081 cgtaccttgg ctctcaatcg tggggagaaa cttggtgtct tgaagatcgg ttttgaacat
     4141 gcgacggacc gtattcttgc cttctttgct actcgtttca aggtgaaaaa tgcttatatt
     4201 gatgaagttg ttcagcaatc cgttaagaaa aaggtcttgc ctgctatcga gcgtcgtatt
     4261 cggacagaat taactgagaa agctgaagaa ggagctatcc aacttttttc tgacaatctg
     4321 cgcaatctcc tcttggttgc tccactgaaa gggcgcgtgg ttcttggatt tgacccagcc
     4381 tttcgtacag gtgccaagtt agctgtcgtg gatgcaacag gaaaaatgct gacaactcag
     4441 gttatttatc ctgttaaacc agcatcagct cgtcaaatcg aagaagccaa gaaagattta
     4501 gcagatttaa ttggtcaata cggtgtagag attattgcca ttggaaatgg aacggccagt
     4561 cgtgaaagtg aagcttttgt agcggaagtt ctgaaagatt tccctgaagt cagctatgtt
     4621 atcgttaatg aaagtggtgc ttctgtctat tctgccagcg aacttgctcg tcaggagttt
     4681 ccagacttga ccgttgaaaa acgctctgcc atttctatcg cccgtcgttt gcaagatcct
     4741 cttgcggaat tggtcaaaat cgatcctaag tcaattggtg tcggtcaata ccaacacgat
     4801 gtcagtcaga agaaactatc tgagagtctg gactttgttg tcgatacagt ggttaaccaa
     4861 gttggtgtca atgtcaatac agctagccca gctcttcttt cacacgtagc tggactcaac
     4921 aaaactatct ctgaaaatat tgtcaaatac cgcgaggaag aaggaaaaat cacttcacgc
     4981 gcccaaatca agaaagttcc tcgtctggga gccaaggcct ttgagcaggc tgctggtttc
     5041 cttcgtatcc ctgaaagtag caatatcctt gataatacag gagttcaccc agagaattac
     5101 actgcagtta aggaactctt caaacgttta gatattaaag acctaaacga agaagcccaa
     5161 agcaaactca agtccctttc agtcaaggaa atggctcaag agctagacct cggtccagaa
     5221 acccttaaag atatcattgc agatcttctc aaaccaggtc gagatttccg tgattccttt
     5281 gacgcacctg tgcttcgcca agatgtccta gatatcaaag acctagtggt aggtcagaag
     5341 ctagaaggtg ttgtgcgtaa cgttgttgac ttcggtgcct tcgttgatat cgggattcac
     5401 gaggacggct tgattcatat ttctcatatg agtcgcaagt ttatcaaaca ccctagtcaa
     5461 gtggtgtcag ttggagattt ggtgaccgtt tgggtcaaga aaattgatac tgaacgtgaa
     5521 aaagttaatc tgtcgctcct cgctccaaat gaaactgact gattatgtca agcaggtttc
     5581 actagaagac ttcgggagag cttttatcca tcatgtccag tggaataggc gtctacgttc
     5641 gacaggtggg cgatttttcc ccaaagatgg gcatctggat tttaatccca aggtttatca
     5701 gaaactgggt atggaggttt ttaggaaaat tgtccgacat gaactctgtc attatcacct
     5761 ttatttccaa gggaagggct atcaacacaa ggatcgggat tttaaggaac tgttgaaagc
     5821 agtggatgga ttaaggtttg taccatcctt gcccaatagt aactctaaac cactcaagct
     5881 ttatcgttgt caatcctgcc agcaaaggta tcagcgcaag cgtaggattg ataccaaacg
     5941 ctatcgctgt ggactttgtc gaggtaaatt gcttctgata aatcagcctg aggactgatg
     6001 aaagccgagc ctccccgtga tatactatgt ctaacctagc agaaagagga aatatcatga
     6061 acagtaaatt ttataaaatg agacgcaatc gcatgatttc aggagttctg gcaggtctgt
     6121 cagacaagtg gaattttgat gttaccctag ttcgtttctt gtttgccatt tttacagttg
     6181 caaactttgg acttggcgtg attatctata tcatcctagc ttctatcatg cctaccaagg
     6241 aagaaatcga agcagaaatg tacggaacag gcccacgtaa acgcaaagaa gcccaagcca
     6301 ttgacgacaa tgaaggctgg ttttggtgag gttctacaga agatttggaa taagcaaaaa
     6361 gctttaaatc aatagtctaa actgcttgat ttaaagcttt tttactttta tactcaataa
     6421 aaatcaaagt gcaaactagg aagccagcca caggctgtaa tttagtcggc aatgtgaagt
     6481 tgacatagtt tgcactttga tttttgaata gtattaataa tatttcgcca gcttcatcca
     6541 caaactatag tggattggaa ctagaatagt acacctctac ttctaaaaca ttgttagaaa
     6601 tcgatttgac tatcctgatc gatttgtcct gttcttattt cattttatta taaaagcagt
     6661 aatttaaact cagtttttta atctattttt gctgctgaga caatacattt ttggaaaaat
     6721 ggtggatgct gataacaact gataaccagc aaataacata agcagtgccg gtaaattctg
     6781 taccgataaa gtgtgtgtgt tcaactaaga gctgaccgat gaatggagag agcagataga
     6841 gaagtccgat gagtatatgt tctttgtgtt tcattaaagc gcaccttctt tccttatagg
     6901 ttgaacgact tgcaagtgtt aaattgaatg gtatgttatc taggtaagct tactcaaatg
     6961 atagttcccg cttcctcctt tccaaagtaa gccttttcat acttatattt tacaacttta
     7021 aaaataggaa atcaaatcat tttctaagta attttgctta tatttcaccc aatcttacaa
     7081 aaatgtaaga ttaaagtctc ttttgtaagg ttaggttatg gcaagcggtc tttttttgat
     7141 gtaaactaga ctcataaaga acaaaggagt aacatcatga aacaaatctt acataagaaa
     7201 actagaaaac caagtcacaa agaaattgag cgcgttcagc tgggatgcac tatgatgcaa
     7261 gctacatttc atttgatggg atattaagaa aggagattct catgacactt ttagatgtaa
     7321 aacacgttca aaaaatttat aaaacacgtt ttcagggcaa ccaagtagaa gccctcaagg
     7381 atattcactt taccgtcgaa aagggtgact acgttgccat catgggtgag tctggttctg
     7441 gtaaatcaac tcttctcaat attctagcta tgctggataa accaagtcgt ggtcaggttt
     7501 acttgaatgg aactgacacc gcaaccatta aaaattcaca ggcctctagc ttccgtcgtg
     7561 aaaagttggg ctttgtcttc caagacttta acttgctaga tactctatct gtaaaggaca
     7621 atatcttgct tccgcttgtc ttgtcaagaa gacctattac agagatgatg aagaaattgg
     7681 tggtgacagc tgagaatctg ggaataaacc aattacaaga gaagtaccct tacgagattt
     7741 ctggtggcca gaaacagcgt gtagcagtag cacgcgccat catcactgaa cctgaaattc
     7801 tccttgcgga cgaaccgaca ggagctcttg actccaagtc atctgcagcc ttacttgatg
     7861 tctttgatga aatcaatgag cgcggccaaa ccattctcat ggtaacccac tcaacagcag
     7921 cagctagcag agctaaacgt gtactcttta tcaaagacgg cattctttac aatcaaatct
     7981 accgtggaga gaagacagaa cgtcagatgt tccaagaaat ctctgatacc ttgactgtca
     8041 tggcaagcga ggtgaattag tatgtttcga ttaaccaata agttagcggt atcgaacttg
     8101 attaaaaacc gcaaactcta ctatcctttt gcgctggctg ttctcttggc agtcactgtc
     8161 acctatctct tttactctct aaccttcaat cccaagattg ctgaaattcg tggaggaaca
     8221 accattcagg ctacacttgg atttggtatg tttgtcgtca cccttgcgtc agccattatc
     8281 gttctctatg ccaatagttt tgtcatgaag aaccgttcca aggaactagg aatttatggc
     8341 atgttgggct tggagaagcg tcatcttatc agtatgacct ttaaggagtt agtggtattt
     8401 gggattctaa ctgttggagc gggtatcggt attggagcct tgtttgacaa gttaattttc
     8461 gctttcctgc tcaaactaat gaaattgaag gttgagctgg ttgctacctt ccagacgaaa
     8521 gttgtcatta cagtgcttgt tgtcttcggt ttgattttcc taggcctcat gttcctgaat
     8581 gcccttcgaa tcgcccgtat gaatgccctc cagctctctc gtgagaaagc tagtggagag
     8641 aaaaaaggtc gcttccttcc tctccaaacc attcttggtt ccataagttt aggaattggc
     8701 tattatcttg cccttacggt aaaagatcct cttacagcct taacaacctt cttcatagct
     8761 gttttactgg ttatctttgg gacttatctc ttgtttaatg cagggattac cgttttcctc
     8821 caaatcttaa agaaaaataa gaaatactat taccaaccaa ataatctcat atctgtttct
     8881 aacttgattt tccgtatgaa gaaaaatgca gttggactag ccaccatcgc tatcttgtca
     8941 acaatggttt tggtaaccat gtcagcagcg acaagcattt tcaattcctc agaaagcttt
     9001 aaaaaagttc taaatcctca tgattttggg gtttcagggc aaaatgttga aaaagaagac
     9061 ttggacaaac tcttgagcca gtttgcaagt gacaaaggtt atagtgtcaa agagaaagaa
     9121 gtacttcgtt acagtaactt tggtattgca aatcaagaag gaactaagtt aactattttt
     9181 gaaaaaggac aaaaccgtgt ccaaccaaaa acagttttca tggtatttga ccaaaaagat
     9241 tatgaaaata tgactggtca aaaactgtct ctatcaggaa atgaggtcgg actctttgca
     9301 aagaatgagg gagttaaaga acagaaagct ctaactctaa atgatcatca attttctgta
     9361 aaagaagaat ttactaaaga ttttattgtc aaccatgttc caaatcagtt taatattttg
     9421 actgctgatt acaattacct tgttgtacct gatttacaag cctttttgga tcaattccca
     9481 gattcggcta tctataatca gttttacggt ggtatgaatg taaatgccag tgaagcagaa
     9541 caactcaagg tcgctgagga gtatgaaaaa tacttacaaa agtttaatgc tcaattaaac
     9601 actgaaggta actatgtgta tggtagcact ctagcagatg ctagtgctca gatgagtgcc
     9661 ctctttggtg gtgtcttctt tatcggtatt ttcttatcca ttatctttat ggtcggaacc
     9721 gttctggtca tctactacaa acaaatttct gaaggatatg aagaccgtga gcgctttatt
     9781 atcttgcaga aagtcggttt agatcaaaag caaatcaagc aaaccatcaa caaacaggtt
     9841 ttaactgtat tcttccttcc tttgctcttt gccttcctac atctagcctt tgcctaccat
     9901 atgcttagtc tgattttaaa agtgattggt gtactggata cgactatgat gttgattgtg
     9961 accttgtcta tctgcgctat cttcctcatc gcctatgtgc tgattttcat gattacttca
    10021 agaagttatc gcaagattgt gcaaatgtaa aaaagatacc tcgacttcaa aatcgaggta
    10081 tttcttgtat tctaaatgct gaaaagttgt tcgagcagga aggtaactcc catggtcaag
    10141 agaccaatag caaggttccg aatcatagct gttttggttg gggcttttcc aagtctagca
    10201 cttgtgtaac cagtgagaag aagggccaca ccgacaataa ggacggtagc agggatgcgg
    10261 taatcacttg gaaaaatggt cactgacagc attggaggca aacttctaag gaaaaaggca
    10321 acgaagctag aaatggcagc gtgccaagga ttggtaaatt cttcatactc aatcccatat
    10381 ttttcctcta ccagagcctt gagtggattt ttaagaaaga tcttattagt caagagttgg
    10441 gcagaagttt tgaattcttc attttggata taagcagcat agagggattt tttggctagt
    10501 tccctatctt ggtctagcaa gagtttttct cgcgaaacgg cagcttcctc ggtatctttt
    10561 ggagttgaaa cggatacata ttctccacca gccattgaaa aggcaccagc taagatagcc
    10621 gcaaatcctg ataaaaagat aatccagata ttggtcgtgg cactggcaac cccgataacc
    10681 acaccagcaa tggaaataat tccatcgtta gcatcaagaa cacccgcacg caggatattt
    10741 aaacgacctg caaaatttga atcaatttcg tgatttgttt ctgacgctaa atttcaagtt
    10801 caagttagcc atcca
//
LOCUS       DAVBCA010000064        10814 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.064, whole genome shotgun sequence.
ACCESSION   DAVBCA010000064 DAVBCA010000000
VERSION     DAVBCA010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10814)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10814)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10814
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.064"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            1..269
                     /locus_tag="VQU19_001772"
                     /pseudo
     CDS             1..269
                     /locus_tag="VQU19_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(385..1188)
                     /locus_tag="VQU19_001773"
     CDS             complement(385..1188)
                     /locus_tag="VQU19_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HET2480983.1"
                     /translation="MQSTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNTPFQQHSKY
                     FRDALVLDNAKILQRRSEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(1467..2222)
                     /locus_tag="VQU19_001774"
     CDS             complement(1467..2222)
                     /locus_tag="VQU19_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HET2480984.1"
                     /translation="MSKHPHYELLNLIGYGLAKFDKLFIKEFQCSSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPYFDNNRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYAEIVKM
                     LLASEGKKTGITIVEKPIVRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDARLY
                     GDGYDFQVDVQEYSYLAEVKGIRKSKGRVRLTAKEFEKVKEFQSDFILSLVTNLDDIP
                     KLVLIDNPLKHFEFKKNIIKNEIIEYRSVEDLY"
     gene            complement(2292..4943)
                     /locus_tag="VQU19_001775"
     CDS             complement(2292..4943)
                     /locus_tag="VQU19_001775"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HET2480985.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ISRYDLGRESFLTKVWEWKDEYSTTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPKFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTDDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNEAGEIYVGEEAPAGDGWKQDEDVLDTWFSS
                     ALWPFSTMGWPNTETTDFKRYYPNSTLVTGYDIIPFWVSRMIFQGIEFTGKSPFKNAL
                     IHGLIRDEEGRKMSKSLGNGIDPMDVIDKYGTDSLRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNEGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEEEKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQISEGSIVTAEYPTVNPAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIFLPLVDLLNVEEELARLEKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     ERDKQADYQAKYDATVARIDEMKKLVK"
     gene            complement(4936..5514)
                     /locus_tag="VQU19_001776"
     CDS             complement(4936..5514)
                     /locus_tag="VQU19_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HET2480986.1"
                     /translation="MHLFIIGAPASGKMTIGQELSRLTDATLFYNHQAIDFALEIYQD
                     YTEEMWEFVRGITFSFLGASARNQRSVILTDVIDFSNQYQLMYLKQIQNLLDDYHQEI
                     LFVELETSLEECIRRNRTENRLKHKPLKRHIEVSEREILETAETLQLNSQYQPNELHH
                     YFKINNTNLSAEEAAKQIQNKINKIEKGHTHV"
     gene            complement(5514..5984)
                     /locus_tag="VQU19_001777"
     CDS             complement(5514..5984)
                     /locus_tag="VQU19_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2480987.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGYG
                     IVVKGTDKIVGSVDFNHRHEDDVLEIGYTLHPDYWGRGYVPEAARALIDLAFKDLGLH
                     KIELTCFGYNLQSQRVAEKLGFTLEARIRDRKDAQGNCCDDLRYALLKSEWEVI"
     gene            complement(5971..6549)
                     /locus_tag="VQU19_001778"
     CDS             complement(5971..6549)
                     /locus_tag="VQU19_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HET2480988.1"
                     /translation="MKQSFKTNKLYYGFPVFILGYQDQNFGYNITTCSSSYSLGDWVV
                     IGVVARENAAEQIKQYQKFTVNISDETSMLAMEQAGFISHQEKLERLGVHYEISERTQ
                     TPILDACPLVLDCRVDRIVEEDGICHIFAKILERLVAPELLDEKGHFKNQLFAPTYFM
                     GDGYQRVYRYLDKRVDMKGSFIKKARKKDGKN"
     gene            complement(6832..7227)
                     /locus_tag="VQU19_001779"
     CDS             complement(6832..7227)
                     /locus_tag="VQU19_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HET2480989.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLALKGIGPATIKKLKENGIKFK"
     gene            complement(7323..7577)
                     /locus_tag="VQU19_001780"
     CDS             complement(7323..7577)
                     /locus_tag="VQU19_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HET2480990.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKVGKGFHDLPEGLFGERNY"
     gene            complement(7586..8920)
                     /locus_tag="VQU19_001781"
     CDS             complement(7586..8920)
                     /locus_tag="VQU19_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HET2480991.1"
                     /translation="MTDEWIHILRDILLELHNGASPESVQDRFDATFTGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVLDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYELMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTVKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKTIMKRLREGSKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            complement(8920..9153)
                     /locus_tag="VQU19_001782"
     CDS             complement(8920..9153)
                     /locus_tag="VQU19_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HET2480992.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLTGTPMDKIVRTLEANGYEVIGLD"
     gene            9184..9258
                     /locus_tag="VQU19_001783"
                     /pseudo
     CDS             9184..9258
                     /locus_tag="VQU19_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            9247..9372
                     /locus_tag="VQU19_001784"
     CDS             9247..9372
                     /locus_tag="VQU19_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004238277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysyl-tRNA synthetase"
                     /protein_id="HET2480993.1"
                     /translation="MDRTDEVSNHTYSKVKLTWFEEIFEEYKMILLLILYHMERD"
     gene            complement(9422..9562)
                     /locus_tag="VQU19_001785"
     CDS             complement(9422..9562)
                     /locus_tag="VQU19_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480994.1"
                     /translation="MKFFWTILAILFIKPIIGIVKFFWMIISFAVQLLFYKILDWFFK
                     LI"
     gene            complement(9559..9741)
                     /locus_tag="VQU19_001786"
     CDS             complement(9559..9741)
                     /locus_tag="VQU19_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2480995.1"
                     /translation="MNPIKAFAKIYGNYFLTVQGVKVMKTIKKDDHVVVGLGKLFIAD
                     KLMDTARWLIKPEERE"
     gene            complement(9743..10526)
                     /locus_tag="VQU19_001787"
                     /pseudo
     CDS             complement(9743..10526)
                     /locus_tag="VQU19_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         3149 a         2386 c         2000 g         3279 t
ORIGIN      
        1 cgacacgatt cttatcatcg gttcctaaga gtaagggaat tcaagcatct atgtcacgca
       61 agggaaacag ccaagacaac ggtatgatgg agtccttctt tgggattctg aaatcggaaa
      121 tgttttacgg ttatgagaag tcgtttcagt cgcttaagca attggaacaa gccattatag
      181 actatattga ttactacaac aataaacgaa ttaaggtaaa actaaaagga cttagccttg
      241 tgcaatacag aactaaatcc ttcggataaa ttatttgtct aactttttgg ggtcagtaca
      301 cctaaaactt tgatgatata cgttttcttg tgagaatatt tacttcattt ttgcctaaaa
      361 ttcaatgttt actcagtatt tggattatga aaaatcgagg tctaaatcta gatacatttt
      421 ttctgaagac aaatcatttt gaccaccgag caagagattt tcaaaaaaag ctgttaaaaa
      481 ctcagaacgt cgctgtaaaa tctttgcatt atctaatacc aaggcatcac gaaaatattt
      541 ggaatgttgc tgaaatggtg tattatcaat atcaaaacca aactcacgaa gatactgaat
      601 caaaaagacc gttactgtcc gagtgtttcc ttcgcgaaat ggatgaatct gccagattcc
      661 tgaaataaaa tgctggattt gtttaaccac atccgcctga gttagtgtcg catatgcaac
      721 ttgtttttcc tgattaaaat cataatctaa ggtcatttga atcatggagt aatcagagta
      781 cacaacactt tcaccattca aaacaggttc attctttgtg atattggtct gacgaaattg
      841 ccccaccgga atagagggtt caaatatatc ttgaaacaac tccttatgaa tagcaagtaa
      901 ggtcgcagga ctaaagctaa agcctcttcg agacaatagt tctacaatac gtagagaaac
      961 caagtctgcc tcttccgtac ttgcatcaat agtatggtga taagccgttg catcctcata
     1021 aacctgctca taagtcagtt ctccccggga ctgtttctca gccaaagatt ccatatacgc
     1081 tgatggcact agattgtcaa ctttctgcag accaaaacct atccgccata aatcacgctt
     1141 cgcttcataa gacaagtttg gattgtcaat gttgtaagtt gattgcatag aaatatcctt
     1201 tcaattgttt ttcttcatta ccagtaaatc acgaaattgg ttggaaactg gcttaaacta
     1261 taaaaagtcc tcacaatagg ttctatgata tatatatata tacttcatgt aaataataaa
     1321 agagttataa tcagcactac tgataaattc aataccgatt tcgccatctt aaaacttagt
     1381 caaacgaata ccgttgattt ccagttcatt aagtcgttga cctgtcaaga cttctcgttc
     1441 cttcaactgg aaaagttaag ggggaactaa tacaaatcct ctacgcttct atattcaatg
     1501 atttcatttt tgataatatt ctttttaaac tcaaaatgtt ttaaaggatt atcgattaac
     1561 actaactttg gaatatcatc tagatttgtg accaaggata aaataaaatc cgattgaaac
     1621 tccttgactt tttcaaattc ttttgcagtt aaacgcacac gccccttaga ttttcggata
     1681 ccttttactt cggcaaggta agaatactct tggacatcta cctgaaagtc atatccatca
     1741 ccataaagac gggcatcggt taactgtcca ccttggaatt tttcttcttt atcaaaatga
     1801 aggataaaat aattctcagc ctccattccc gtttcctgta gacgtttgaa tttagttcga
     1861 actattggtt tttcaacgat ggttatgcct gttttcttcc cttcactggc aagtaacatt
     1921 ttaactattt cagcataact atgaacatct tcatttccaa acatcatatc aattaaatct
     1981 ttacgaaaac gataaacttc agctttctgc caccaacctt ttcgattatt gtcaaaataa
     2041 ggatcaaata aatccattct attttttaca actccagttg tttcagcaat tcccagagaa
     2101 accacatagc gataaaactc cgacttgcta gagcattgaa attcttttat aaaaagcttg
     2161 tcaaacttgg caagaccgta gccaattaaa tttaacaatt cataatgagg gtgtttggac
     2221 atcactttct ccatcaatag atattgattt cattatacca aaaaacacgg ctcatcaccg
     2281 tgtttctgtg tttatttcac caacttcttc atctcatcaa tacgtgctac ggtcgcatca
     2341 tacttagctt ggtaatctgc ttgcttgtcg cgttcttttt ggacaacttc tggtttagcg
     2401 ttggcgacga agcgttcgtt gctgagtttt ttgccaacca tgtcgagttc tttctgccat
     2461 ttggcaagtt ctttttccag acgtgccaat tcttcttcga cattcaagag gtctaccagt
     2521 ggcaagaaga tttcggctcc tgtgatgacg cttgacatag ccagttcagg tgcagggatg
     2581 gttgatgcga tttccaagtg ttcaggattt gtgaaacgtt tgatgtagtt gacattgctg
     2641 ttaaagaagg cttccaagtc gctatcgctt gtcttaacaa ggatagtgat aggcttgctt
     2701 ggagcaacgt ttacttccgc acgcgcatta cgaacggcac ggatcaagtc tttaaggctt
     2761 tccacaccag tgtgagcagc aaggtcttca aaggctgggt tgacagttgg gtattctgct
     2821 gtaacgatag atccttctga gatttgtcca aagatttcct ctgtcacaaa tggcatgatt
     2881 gggtgaagga gacgaaggat cttgtccaaa gtgtatagta gaacagaacg tgtgatgact
     2941 ttctcttctt cgttatcgct ataaaggact tccttggtca actcaacata ccagttggca
     3001 aattcttccc agatgaagtt gtaaaggata tgaccagcca caccaaactc gaacttatca
     3061 aagttttcag taacttttgc aatggtttcg ttgagattgt ggagaatcca gcggtccgtc
     3121 acattaccag cctcacctgt tgcaactttt gtgacattgt catgcgccac atccagcgtc
     3181 aaaccttcat tgttcatgag gatatagcga gaaatgttcc aaattttgtt aataaagttc
     3241 catgaagcat ccattttctc gtaagagaaa cgaacgtctt gaccaggagc tgagccgttt
     3301 gacaagaacc aacgaagact atctgtacca tatttatcaa taacatccat tgggtcaatg
     3361 ccatttccaa gagatttaga catcttacgt ccttcttcat cacgaattag accatggata
     3421 agagcatttt taaatgggct ctttcctgta aattcaattc cttggaaaat catgcgtgat
     3481 acccagaaag gaataatatc atagcctgtt acgagtgttg aatttggata gtagcgttta
     3541 aagtcagtag tttcggtatt aggccagccc atggttgaga agggccagag ggcagagctg
     3601 aaccaagtgt caaggacatc ttcgtcctgt ttccagccat cgcccgctgg ggcttcctcg
     3661 ccgacataga tttcgcctgc ttcattatac caagcaggga tttggtgacc ccaccagagc
     3721 tgacgggaaa tcacccagtc gtggacattt tccatccatt gcaggaaggt gtcgttgaag
     3781 cgcggtgggt aaaattccac cttgtcatct gtgtcttggt tggcaatggc gttcttggcc
     3841 aattggtcca tcttgacgaa ccattgagta gacaagcgtg gctcaactac gacacctgtc
     3901 cgttctgagt gaccgactga atggacacgt ttttcgattt tgacaagggc accgatttct
     3961 tccaacttag caacgactgc cttacgagct tcaaaacgat ccatgcctga aaattcaaag
     4021 gcaagctcgt tcatagttcc gtcgtcgttc atgacgttga cttgtggcaa gttatgacgt
     4081 tggccaacca agaagtcatt tggatcgtgg gcaggtgtga ttttcacgac accagtacca
     4141 aacttaggat ctgcgtgctc atcaccaacg attgggatta atttattagc aattggaagg
     4201 atgacatttt taccaatcaa gtccttgtag cgcgggtctt ctgggttgac cgcaaccgca
     4261 acgtccccaa acatggtctc aggacgagtt gtagcaactt caagggcgcg tgaaccatct
     4321 tccagcatgt aattcatgtg atagaaggca ccttcgacgt ccttgtgaat aacctcgata
     4381 tcagaaaggg ctgtgcgagc tgctgggtcc cagttgatga taaactcacc acggtagatc
     4441 cagcctttct tgtaaaggtc cacaaagacc ttacgaacag cttttgacaa accttcgtca
     4501 agagtgaaac gctcacgaga gtagtctaca gagagcccca tcttgcccca ttgttccttg
     4561 atagtagtgg aatattcgtc tttccattcc cagactttcg tcaagaaaga ctcacgacca
     4621 aggtcatagc gggaaatgcc ctcaccacgc aagcgctcct ctaccttagc ctgagtggca
     4681 atccctgcgt ggtccatccc aggaagccaa agggtatcaa aaccttgcat gcgtttttga
     4741 cggatgataa tatcttgcaa agttgtatcc caagcgtgac caaggtgaag tttacctgta
     4801 acgtttggtg gtggaataac gattgaataa ggcttagcct tttgatcgcc tgaaggcttg
     4861 aaaacatcag catcaagcca tttttggtaa cgaccagcct caacctcggc tggattgtat
     4921 ttagatgaaa gttctttaga catgtgtgtg tcctttctct attttgttta ttttattttg
     4981 aatttgctta gcagcttctt ctgcagacaa attcgtatta tttattttaa agtagtggtg
     5041 caactcattc ggttgatatt gggaatttaa ttgaagtgtt tcagcggtct ctaaaatttc
     5101 tctttcagat acctcaatat gtcgttttaa gggtttgtgc tttaatcgat tctccgttcg
     5161 atttcgacgt atgcactctt caagacttgt ttccaactca acaaaaagaa tctcttgatg
     5221 ataatcatcc aacaaattct gaatttgctt taaatacatc agttgatact gatttgaaaa
     5281 atcaattaca tctgttaaaa ttactgatcg ctgatttctt gcacttgctc caaggaatga
     5341 aaaagtgatt ccacgaacaa attcccacat ttcctctgta tagtcctgat agatttctag
     5401 tgcaaaatca atggcttgat ggttataaaa tagggtagca tccgtcagtc gagataattc
     5461 ttgaccaatg gtcatttttc ctgatgctgg agcaccaatg atgaaaagat gcatcaaatc
     5521 acctcccact cactcttcag caaggcatat ctcaaatcat cacagcagtt gccttgagca
     5581 tctttacggt ctcttatgcg agcttcgagg gtaaagccaa gcttttccgc gactcgttga
     5641 ctttgaaggt tatatccaaa gcaagttagt tcaatcttgt gaagacccaa atctttaaag
     5701 gctaagtcaa tcaaggcacg cgcagcttct ggcacataac ctcgccccca atagtctggg
     5761 tgtaaggtat agccgatttc cagcacatca tcttcatggc gatggttgaa atcgacagag
     5821 ccaacgatct tatccgttcc tttgacgaca atcccgtagc ctgctggata ggcgacctct
     5881 ggcaaactag catagtcaaa gatatcctca gcatccgcca cagtacggac tcgtaaaacg
     5941 agacgttctg tttcgatttt atctggcagc tcagttcttg ccatccttct tcctcgcttt
     6001 tttgatgaaa ctgcccttca tatctacacg cttatccaga tagcgataaa cgcgctgata
     6061 tccatctccc atgaaatagg ttggggcaaa cagttgattt ttaaaatgtc ccttttcatc
     6121 caggagttct ggggcaacaa gtcgctcaag aatcttggca aagatgtggc aaataccgtc
     6181 ttcctcaaca atcctatcta cccgacaatc taaaacaagt ggacaggcgt ctaaaatagg
     6241 agtctgagtt cgttcagaaa tttcataatg cactcccaaa cgttccaatt tctcctgatg
     6301 actgataaaa ccagcctgct ccatcgcaag catagaagtt tcatcagaaa tattcacagt
     6361 aaatttttga tactgtttga tctgctctgc ggcattctct ctcgcaacga ctccaatcac
     6421 aacccaatct cctagactat acgaggaact acaggtcgtg atgttatagc caaaattctg
     6481 atcttgatat cctaaaataa aaacaggaaa accataatat agtttattag ttttaaatga
     6541 ttgttttata acaacctcct ttgactaaga cacaaaagaa aagccctgcc atctacatga
     6601 cagggacgaa tgtatttatc cgcggtacca cccaatttcg ggccaagccc gcatctttag
     6661 tctttaaaat aaaaagacag aaatatttca ttttttcagt cattagcaac cagttttgac
     6721 acatttgtgg acttctcagc gccgccactt tctgtaaaat gtgggattca aaacacctct
     6781 aatagctcta ttgtagcaag tttttctcgg aaatgcaagg ctcaagaaaa attacttgaa
     6841 cttgatgcca ttttctttca atttcttgat ggtagctggg ccgattcctt tcaaggcaag
     6901 gagttctttt tcagtccagt ttttgaaatc tgaagcagac ttgattcctt catcatagaa
     6961 agtcttggca cgatcaagtg gaagtccacc caagtttgct gcaaaatctt ctacagaatt
     7021 agctactttt tgagcttgct ctttggtagc ttctactgct tgttcaactt ttttagaaac
     7081 agccttacca gctgcgcttg ctgactgttc tgcacgcttc acgacttttt ttgtctcatc
     7141 tacaacctta gtcacagtac ttgaaaaggc acctgcgcga cggaggccat ttcgtaattg
     7201 ttttttacga ttgagtttct ttgacatgat aaaatccttt caataaaaaa tccctgctct
     7261 gacaaggatt taacataaac attctatcaa gattttagtg aaaaatcaag aatctttctc
     7321 gtttaataat ttcgctcacc aaacaagcct tctggcaaat catggaatcc cttgcctact
     7381 ttgaagtttt caaacttacc aagcaagaac tgataagcat ccaagcgact ctcgtagcga
     7441 atcatggcat ctttggcacg ctcgtcctgg tcttcttcgt aaactttttg actttccttg
     7501 tgcgccatgt cgttaatcat gatttgggta ttgacccaag cttcaaattc cttcataaat
     7561 tcttgttcgt aactcatttt tctccttatt ctaatccacg aaaatagtcc gtatcaatct
     7621 cacggtaggg ctggatatcc tgaacatact ccaacactcc ttggaattct ccgtcttcat
     7681 cgtgtactgc agcataggtg atgtggacaa acttacctcg cgactcagac ttgaaccaca
     7741 tttcatactt gtctttgctt ccctcacgaa gcctcttcat gatagttttg accttgtcca
     7801 agtacttagg cggatggcag agttcgacat tgcgcccgac ttgagacggc gtccgtttga
     7861 aaatcatctc atcagctggc gtattgtcat tgtaatactg gaaaatatct tctttattga
     7921 caaaggtaat ctccataggg agatgattga ggatgagatt ggcctgctcg actgaaagat
     7981 agccattacc aaaagcctgt tgactatggc ggtccagcac agcttccttt tccttagggg
     8041 taaaggtaat ggtaaaatgg ccttctggcg tatctatgac ttgttgaact tgaccttctg
     8101 ccgtatctag ctgtacaggc tcctctgcaa tcttttcctc aataaagctc tgtcgttctg
     8161 gcacccattt ctctgacgga cggatgatgg catagccata ggcatcgctc tcctccgcaa
     8221 tctgaagcca gtcatcctga gtaaaagact caaggagaat catgaggagg atggactctt
     8281 ccttgaaaat catactttca aactctgtcg caaaagcttc aaaagcttcc tttacactgc
     8341 taattgacac ttctggtagt gacttgactg tcgttagagc tgtttgaaag agttccctaa
     8401 tctgatcatc cactccccac ataactttgg gaggtgaatc gtgtccatag cgctccatga
     8461 taggaaagaa gagttcttcc ttacgttggt aatggatgtc aaattgcccc acaagcccca
     8521 tctgacgcac caagcccttg cgcatctccg caagcatttc ctcgtcttcc atcaactcat
     8581 aggtatctaa caatctacga atgcgaatca aagctgcacg gagggccaaa ttttcttcct
     8641 taaagacacg aactgggtgc ccagggtgtt cggtatctaa aacttcgaca cctttgatag
     8701 catttttaaa aagattggca tggacatcac agagttccat aacatcttca aaagtgacgc
     8761 ccgaatccga gttcatcagc tcgtgctcca taagggaaat ctcgatggct gacacgcccg
     8821 taaaggtcgc atcaaagcga tcttgaaccg actcaggaga ggcgccattg tgcaattcta
     8881 acaaaatatc ccgtaggata tgaatccatt catctgtcat tagtctaatc caatcacttc
     8941 gtagccattc gcttccagtg tgcgtacaat cttgtccata ggagttcctg ttagcttaga
     9001 accctgttta agtgatactt tacgaccaac tgtattgcgc attaagggat tggcaagggg
     9061 tttaaaaccc aactccacta gaatttccaa gacttctgga tgcttgtcca ccacttctgc
     9121 aacaggaatt gacacatcga tgatattgtc catgacgacc tccattgtat gttctaatac
     9181 tcaatgaaaa tcaaagagca aactaggaag ctagccgcag gttgctcaaa acagtgtttt
     9241 gaggttgtgg atagaactga cgaagtcagt aaccatacct acagcaaggt gaagctgacg
     9301 tggtttgaag agattttcga agagtataaa atgattttac tgcttatatt ataccatatg
     9361 gagagagatt aaaaaactag cagtggagtt cctgctagtt ttctgcgact tggattacca
     9421 tctagataag tttaaagaac caatccaata tcttgtaaaa cagcaattga actgcaaaag
     9481 aaatgatcat ccaaaagaat ttcacaatcc caataatcgg tttgataaaa agaatagcaa
     9541 gaattgtcca gaaaaatttc attctctctc ctctggctta atgagccacc gagccgtatc
     9601 cattagctta tctgcaataa agagttttcc cagaccaaca acgacatggt catctttctt
     9661 tatcgttttc atcactttta caccttgcac ggtcaaaaag taattaccat aaattttagc
     9721 aaaagctttg ataggattca tattattctc ctttgatgat ttcagcctct tttcggattg
     9781 tttcaacatc ttcttgatat tgaacttcac tatagttgac tagcttggat aattctttct
     9841 gcaagctttc ccccattggt ttcatagttg caaaggttaa accacctgaa atgataccac
     9901 ccaagatagg aataaatttc cccattcctt tggccaaccc tcccttggta agattcacac
     9961 caaatatttt taagactttt ttcaaaatag ggtaccaaag cgtctttgtt aaagctttat
    10021 taggcactgt tttcattacc tgtttggcaa ttgttatacc accagcacgt agcaaacaaa
    10081 gcagcggttc cattcacccc taacattacg cctagataaa gcaagagggt attttgagca
    10141 tcttcactca actcctcacg tgaagcccaa agatcctcat aaccataaat ataacctaat
    10201 tcttgggcca atttcagaga gaaaccataa aattgagcca cataagctgg aatggtaatt
    10261 gccatagcaa gccctccagg taatcctgcc aaaacagaag tcccactcgc taataaaaca
    10321 ttatccctaa tacaggcatt agccactcga tctaagattt cttgagataa gagagacgtt
    10381 ggaccttgtt ccaataaggt aggaatgtcc tgtggaccca attctttgga aaacttatcc
    10441 actaaaaatt tcgaacgatc aaccttaaca actggtagtt ttaccacttg ttgtaatact
    10501 tgcatagcta agtcttgttc agccatatac aaactcctta tttctttttt gcaccttatc
    10561 atattatatt tcctacaaaa aaagcatttt ctaattagat aacattaaaa aatacagaac
    10621 ccctttttta tagtaaaata aaacaagaac aggacaaatc gatcaggaca gtcaaatcga
    10681 tttctaacaa tgttttagaa gtagaggcgt actattctag tttcaatata ttttaaaaga
    10741 atatttttcc atttcaaatt caacctattt tcctccacca aaaaagggct ctataatatt
    10801 tgtagtgggt aaat
//
LOCUS       DAVBCA010000065        10764 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.065, whole genome shotgun sequence.
ACCESSION   DAVBCA010000065 DAVBCA010000000
VERSION     DAVBCA010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10764)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10764)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10764
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.065"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            51..233
                     /locus_tag="VQU19_001788"
     CDS             51..233
                     /locus_tag="VQU19_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HET2480996.1"
                     /translation="MKSQKIKVSFTQSKIVTPILLVNKTIVWYGAMPLLGKVDEMTIL
                     RLESASIVSELVAGLR"
     gene            533..1372
                     /locus_tag="VQU19_001789"
     CDS             533..1372
                     /locus_tag="VQU19_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HET2480997.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKTGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGIIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTK
                     NLD"
     gene            1390..3228
                     /locus_tag="VQU19_001790"
     CDS             1390..3228
                     /locus_tag="VQU19_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET2480998.1"
                     /translation="MSYKDTVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPDVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGAPVTPASYGSSVVPILIMV
                     WLMKYIEKIIAKLTPAITKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVKAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     NLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            3241..4656
                     /locus_tag="VQU19_001791"
     CDS             3241..4656
                     /locus_tag="VQU19_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HET2480999.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEN
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSAIPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDELNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            5248..6294
                     /gene="pheS"
                     /locus_tag="VQU19_001792"
     CDS             5248..6294
                     /gene="pheS"
                     /locus_tag="VQU19_001792"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HET2481000.1"
                     /translation="MSTIEEQLKALREETLASLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            6294..6803
                     /locus_tag="VQU19_001793"
     CDS             6294..6803
                     /locus_tag="VQU19_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2481001.1"
                     /translation="MIRKVEMADVEVLAKIAKQAFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            6880..9285
                     /locus_tag="VQU19_001794"
     CDS             6880..9285
                     /locus_tag="VQU19_001794"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HET2481002.1"
                     /translation="MLVSYKWLKELVGIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEILSCEDVPETHLHVCQVNVGEEEERQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKKFADGIQILPENAVPGEEVFSYLDLDD
                     EIIELSITPNRADALSMRGVAHEVAAIYDKAVNFKEFTLTETNEAATDALSVGIETDK
                     APYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDT
                     FEGTDIRVREARAGEKLVTLDGEERDLDVNDLVITVADKPVALAGVMGGQATEISEKS
                     SHVVLEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASLIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VSVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTVTQKLSRQVRTIAE
                     GAGLTEIITYVLTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYA
                     KGILEALFTRLGLEVTYTATAEIASLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSVIEAALQPAAPFVEITKFPAVSRDVALLLKAAVTHQEVIDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEKKVNA
                     EVR"
     gene            complement(9458..10459)
                     /locus_tag="VQU19_001795"
     CDS             complement(9458..10459)
                     /locus_tag="VQU19_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HET2481003.1"
                     /translation="MIKTFLSALSVILFVIPIITYSFFPSSNLNIWLSTRPILAQIYA
                     FPLATATMAAILSFVFFSLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIADDFNATMRHGALAKISSHRDAL
                     NVLPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            10615..>10764
                     /locus_tag="VQU19_001796"
     CDS             10615..>10764
                     /locus_tag="VQU19_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET2481004.1"
                     /translation="MQDNYTTKGKHLTIDSRRLIERWKKEGKSNREIASLLGKVPQTI
                     HTEIKR"
BASE COUNT         3450 a         1733 c         2287 g         3294 t
ORIGIN      
        1 accccaaaag ttagattttt tctgtctaac ttttggggtg tagttcacag ttgaagagcc
       61 agaaaattaa agtgtctttt actcaatcaa aaatagtaac gcctattctt ttggtgaata
      121 agactattgt ttggtatggt gcaatgccat tattagggaa ggtagatgag atgaccatat
      181 tacgtttgga atcagctagt atagtttctg aactagtggc aggtttacga tagagaaaat
      241 ttttaaaaat ttctatgtat gattttcatt tctttagtga gactgttgcc attatcacat
      301 tcgaatcaca caaaataaaa aaatttctac aagtacttga caaatagatt gaaatatcat
      361 aaaatgaaaa tggttacaga gttattaatt atttaagctt catgtcacca ttaaaaattg
      421 aaataaaagg atgttatcac taatacaagt gagcaggaac ctatttaatc acatcggaag
      481 aagtttcttg atgtttttaa gtaggttcct tttattttaa aagggaaatt ttatgatcat
      541 aaaacgaata ctaaaccaca atgccgtaat tgcgcaaagt aaaaaagata tcgatattct
      601 tctttttgga aggggcatag cttttggaag aaaaactgga gataaagtaa atccaattga
      661 tattgagaaa agtttttttc tcaaaaatag agataatatg acccgtttta cagagatgtt
      721 tattaacgtt cctttggagt tggtgtacat caccgaaaaa ataattaacc taggtaaaat
      781 aacattgggt aataattttg atgaaattat ctatattaat ttaacggatc atatttcttc
      841 gagcatagaa cgttataaag aagggattat tatttcgaat cccctacgct gggaaatatc
      901 gaaatattat aaagaagaat ttgaacttgg gaaaagggct ttacaaataa taaaaaaaga
      961 gttaggtatt gaacttccaa ttgacgaagc tgcattcata gcgctacatt ttgttaatgc
     1021 taatttagaa aataattttc aagagtcgta taaaatcact gaaataatta tgggaattga
     1081 gaaaatcatt caagatttct attgtactga gtttaaccaa gattctattg attattatag
     1141 attcataact catataaaat tatttgctca tcgcttggtt gaaaatacaa cttattgtga
     1201 cgatgatgat gaagacttgt tagcattaat gaaaaataaa tatcctagag aatatgaatg
     1261 tggtgaacag gtggcaatgt ttatacaaac tgagtacaat tatttgctga cttctagtga
     1321 attagtttat ttgatggctc atattcgtcg cttaacaaaa aatttagatt aatagaatag
     1381 gagaatacca tgagttataa agatacggta caaaaaatcc tcgatgtaat tggaggtgaa
     1441 aaaaatgtca atagagttac ccattgtgta acacgtttaa gattagaatt aaaagatgaa
     1501 aatttagtca atgatgatga tgtgaagaag ataccagatg taataggtat tatgaaaaag
     1561 aatggacaat atcaaattat acttggtaat gatgtagcta attattataa agaattcgtt
     1621 aaacttggca attttgaatc cgattcagtt gttcaagggc acaaagggaa tattttagaa
     1681 agaatcattg agtatatcgc tggttccatg actccaatca ttccagcaat gttaggggga
     1741 ggtatgttga aagtcttggt aatcatttta ccaatgcttg gtatattgca atcagattct
     1801 cagactattg cttttttgac attttttggg gatgctccat attatttctt accgctgtta
     1861 ttagcttatt ctgcatcaca aaaattaaaa gtaacatcta cattagctat gtctgtagca
     1921 ggtgtacttc tccatccaaa ttttgttcaa atggtgcaat cagggaatcc tcttagttta
     1981 tttggtgcac ctgtgacacc agctagttat ggttcatcag tcgttccaat tcttattatg
     2041 gtttggttga tgaaatatat tgaaaaaata attgctaaat taacaccagc tattactaag
     2101 agttttttgc aacctacgct agtattatta gtatcaagct gtattgcctt agttgtagtc
     2161 ggacctattg gagtaattgt tggtgaagga ttatcaaatc tagttgggca aatgtatggt
     2221 gtagctggat ggcttacatt agctattctt ggtgctatta tgccatttat tgttatgact
     2281 ggaatgcatt gggcttttgc acctattttt ttggcggcat ctattgctac tccagacgta
     2341 ttaattcttc cagcaatgtt agggtcaaac ttagctcaag gggctgcttc gatggctgtt
     2401 gcattaaaga gtaaaaataa taatacaaaa caaattgctt ttgcagcagg tttctcagcc
     2461 ttacttgcag ggattaccga acctgcatta tatggtgtga ctttaaaata taaaaaaccg
     2521 ctttatgcag ctatgattgg tggtggatta gcgggattat ttgcaggtct tactagtgtt
     2581 aaagcatatc tatttgctgt cccatctttg atagcgttgc ctcaatttat ttattctgat
     2641 gtgccatcaa atattgtaaa tgctttaatt gtggcggtca tttcggttgt tattaccttt
     2701 gtattagctt atatatttgg aatcgatgaa gaagagagtt ctagcaattt agaagttaaa
     2761 gctggagttt caaataaaaa aatgatattt tctcctatat caggagaaat cattccgtta
     2821 agcgatgtcc aggataaaac attttcagat aaattaattg gagacggagt agcgattatc
     2881 ccaagtgaag gtaaggttta tgcaccattt gatgggaaaa ttacaaatat ttttccgact
     2941 aagcacgcaa ttggattgaa gagtgatgag ggtgttgagt tactaattca tattggatta
     3001 gatactgttg agctaaaagg tcaaggtttt attagtcatg tagaagaagg agacagagtt
     3061 ttcaaaaatc agttgatttt tgaaatgaac ttgaatttaa tcaagactaa aggctacgaa
     3121 acagttacac cagtaattgt aacgaatacc aatgattttc tagatgtatt agtattacct
     3181 aataatcaga caatcgagca ttctaaggaa ttactggtaa tattataatg gaggaaagtt
     3241 atgaccattt ttccagatga ttttctttgg ggtggagcgg ttgcagctaa tcaagtagag
     3301 ggagcatata atgaagatgg taagggctta tcagttcagg atgtgttacc caaaggtgga
     3361 ttaggagaag caacagaaaa tcctacagaa gataacttaa aattgatagg tattgatttt
     3421 tatcataaat ataaggaaga tatatccttg ttttctgaaa tgggctttaa tgtttttcgt
     3481 acttctattg catggagtag aatttttcca aaaggagatg aggaagaacc taacgaagct
     3541 ggtttgaaat attatgatga attatttgat gaactacatg ctcacgggat agaaccactt
     3601 gtaactcttt cacactatga gactccatta tatttagcaa gaaaatatca tggatggatt
     3661 gataggagaa tgattcattt ttatgaaaaa tttgctcgaa cagttttaga aaggtataaa
     3721 gataaagtta aatattggct tacatttaac gaagtaaact ctgttttgga attaccgttt
     3781 actagtggag gaatagatat acctaaggag aatctttcga aacaagaatt atatcaagct
     3841 atacatcatg aattagtcgc ctcgagtttg gttacaaaaa ttgctcgtga gattaattca
     3901 gagtttaagg tggggtgtat ggtattagct atgccagctt atccaatgac tccaaatcca
     3961 aaagatgtat gggcgactca tgagtatgag aatctaaatt atctattttc agatgtgcat
     4021 gttagaggtt attatccgaa ttatgcaaaa agatatttta aggaaaatga cattaacata
     4081 gagtttgcag ctgaagatgc agagttatta aaaaattata ctgtagattt tttatccttt
     4141 agctattaca tgagtgtgac tcaatctgct attccaacac agtataattc aggagaaggg
     4201 aatattattg gtggtttagt aaatccttat ttagagtctt cagagtgggg atggcaaatt
     4261 gatccaattg gactacgtat aattttaaat agatattatg accgttatca aatcccatta
     4321 tttatagtag aaaatggatt aggtgctaaa gatcaactaa taaaagatga acttaataac
     4381 ttaaccgtcc aagatgatta tagaattcag tatatgaaag aacatttatt gcaagttgct
     4441 gaagctctac aggatggtgt tgaaattatg ggctatacgt cttggggatg tattgactgt
     4501 gtttctatgt ccactgcaca actttctaaa aggtacggtc tcatttatgt tgatcgaaat
     4561 gatgatggaa atggcacatt caatcgatat aagaaaatgt cctttacttg gtataaagga
     4621 gtgattgaat caaatggaga atccttattc aaatagtttg tttattgatg attagatatt
     4681 atcacggtta aggcaacatc tcattaaata taaaataaag aggtttggaa gacatcaaat
     4741 tctaaacctc tttattttat agggggatta attaatttaa ttttgttaca gagagccgat
     4801 tataaatagt taacttagga tagattggtt atatatagta gactgaatct aaaatagtac
     4861 gaaacaattg ctaaaacatt tatagaaatt aattttactt tcccaatcga tttgttttca
     4921 tcttatttca atccgctata aagttagata agaataagct aacaagcaga agtaagatag
     4981 gtcttgcaag aatggtaaaa atctgataaa ctaagtagta attgaatagg aatctgaaag
     5041 actagtagcc caagggaagt atatcaggga ggagagccgt gactgcaagc tctctatatg
     5101 aaagctgggt gaattcactt gcgcatggat ttagaaatga aggtctgact tgtcagatga
     5161 aaacggatgg taccgcgtgt caacgctccg agtggagttt ttggcatgtg gttttctttt
     5221 tatctacgag agactgatgg aggaaatatg tcaactattg aagaacaatt aaaagcgctt
     5281 cgcgaagaaa cgctggctag cttgaagcag attactgctg gaaatgaaaa agagatgcaa
     5341 gatttgcgtg tctctgtcct tggtaaaaag ggttcgctca ctgaaatcct caaagggatg
     5401 aaagatgttt ctgctgagat gcgtccaatc atcgggaaac acgtcaatga agctcgtgat
     5461 gtcttgactg ctgcttttga agaaacagct aagctcttgg aagaaaagaa agtcgcggct
     5521 caactggcta gcgagagtat cgatgtgacg cttccaggtc gtccagttgc gactggtcac
     5581 cgtcacgttt tgacacaaac cagtgaagaa atcgaagata tcttcatcgg tatgggttat
     5641 caagtcgtgg atggttttga agtggagcaa gactactata actttgaacg tatgaacctt
     5701 ccaaaagacc acccagctcg tgatatgcag gatactttct atatcactga agaaatcttg
     5761 ctccgtaccc acacgtctcc agttcaggcg cgtgctatgg atgcccatga tttttctaaa
     5821 ggtcctttga agatgatctc gccagggcgt gtcttccgtc gcgatacgga cgatgcgacc
     5881 cacagtcacc aattccacca aatcgaaggc ttggtagttg ggaaaaatat ctctatggct
     5941 gatcttcaag gaacgcttca gttgattgtc caaaaaatgt ttggtgaaga gcgtcaaatt
     6001 cgtttgcgtc catcttactt cccattcaca gagccatctg ttgaggtgga tgtttcttgc
     6061 ttcaagtgtg gtggagaagg ctgtaatgta tgtaagaaaa caggttggat cgaaattatg
     6121 ggggccggta tggttcaccc acgtgtcctt gaaatgagtg gtatcgatgc gactgtatac
     6181 tctggctttg cctttggtct tggacaagag cgtgtagcta tgctccgtta tggaatcaac
     6241 gatatccgtg gattctacca aggagatgtc cgcttctcag aacagtttaa ataatgatta
     6301 gaaaagtaga aatggcagat gttgaggtgt tggctaaaat tgccaaacaa gcctttcgtg
     6361 aaacctttgc gtatgataat acggaagagc agttacagga atactttgaa gaggcttata
     6421 gtctgaaaac tttgtcaact gagttgggaa atcctgactc tgaaacctat ttcattatgc
     6481 atgaggagga gatagctggt tttctcaaag tcaactgggg aagtgctcaa actgagagag
     6541 aattagagga cgcttttgaa attcaacgcc tctatgtgct acaaaaattc caaggatttg
     6601 gactaggtaa gcaactgttt gaattcgcac ttgaacttgc tacaaaaaat agtttttctt
     6661 gggcttggct aggtgtttgg gagcataata caaaagctca agcgttttat aaccgatatg
     6721 gttttgaaaa atttagccaa catcatttta tggttggtca aaaagtagat acggattggt
     6781 tactgagaaa gaaattaagg taagaagaga attcttctat tgaaatgata ggaaaggaaa
     6841 agaaccagtg tggcaatggt cattctggag aactaaatta tgcttgtatc ttataaatgg
     6901 ttaaaagaat tggtgggcat tgatgtgcca tcacaggagt tggctgaaaa aatgtcaacc
     6961 acagggatcg aggtcgaagg tgtcgaatca ccagctgccg gtctttcaaa aattgtcgtc
     7021 ggtgagatct tgtcttgcga agatgtgcca gaaactcacc ttcatgtttg tcaggttaac
     7081 gttggcgaag aagaagagcg tcagatcgtt tgtggtgccc caaatgtgcg tgcaggcatc
     7141 aaggttatgg tggctcttcc gggagctcgt atcgctgaca attacaaaat caaaaaagga
     7201 aaaatccgtg gcttagagtc acttggaatg atctgttcac ttggtgaatt gggtatttct
     7261 gactcagttg tacctaagaa attcgcagat ggtattcaaa ttttgccaga aaatgccgtt
     7321 ccaggtgagg aagtcttttc atatctagac ttggatgatg aaatcatcga actttctatc
     7381 acaccaaacc gtgcagatgc cctttctatg cgtggagtgg ctcacgaagt ggcagccata
     7441 tatgacaagg cagtcaactt taaagaattt actttgacag aaacaaatga agctgcgaca
     7501 gatgcccttt ctgtgggcat tgagacagac aaggcgcctt actatgcagc tcgtatcttg
     7561 gacaatgtga ctatcgcacc aagtccacaa tggttgcaaa accttctcat gaacgaaggc
     7621 atccgtccca tcaataacgt tgtagacgtg acaaactaca tcctgctcta ctttggtcaa
     7681 cctatgcatg cttttgactt ggacacattt gaagggactg acatccgtgt gcgtgaagcg
     7741 cgtgctggtg aaaaattggt gaccttggac ggtgaagaac gtgacttgga cgtgaatgac
     7801 ctagtcatca ctgttgcaga caagccagta gcccttgcag gtgtcatggg tggtcaagca
     7861 acagaaatct ctgaaaaatc tagtcatgtt gtccttgaag ctgctgtttt caatggcaaa
     7921 tctatccgta agacaagtgg tcgcctgaac cttcgttctg agtcatcttc tcgctttgaa
     7981 aaaggaatta atgtggcaac agttaatgaa gcccttgatg cggcagctag cctgattgcg
     8041 gaacttgcag gtgcgacggt gcgtaagggt atcgtttcag cgggtgagct tgatacttca
     8101 gatgtagaag tttcttcaac tcttgctgat gttaaccgtg tcctcggaac tgagctgtct
     8161 tatgctgatg tcgaagacgt cttccgtcgt cttggctttg gtctttctgg aaatgcagac
     8221 agctttacag tcagcgtacc acgtcgtcgt tgggatatca caatcgaagc tgatctcttt
     8281 gaagaaatcg ctcgtatcta tggatatgac cgcttgccaa ccagccttcc aaaagacgat
     8341 ggtacagctg gtgaattgac tgtgacacaa aaactcagcc gtcaagttcg taccattgct
     8401 gaaggagcag gtttgacaga aatcatcacc tatgttctaa caactcctga aaaagcagtt
     8461 gagtttacgg ctcaaccaag taaccttacg gaactcatgt ggccaatgac tgtggatcgt
     8521 tcagtcctcc gtcaaaatat gatttcaggt atccttgata ccgttgccta caacgtggct
     8581 cgtaagaata aaaacttggc cctttacgag attggaaaag tctttgaaca aacaggtaat
     8641 ccaaaagaag aacttccaaa tgaaatcaac agttttgcct ttgccttgac aggcttggtt
     8701 gctgaaaaag atttccaaac agcagcagtt ccagttgatt tcttctatgc taaaggaatc
     8761 ctagaagcgc tctttactcg cttgggacta gaagtgacct atacagcaac agctgagatt
     8821 gccagccttc acccaggacg tacagcagtc atttcactcg gtgaccaagt tcttggtttt
     8881 cttggccaag tgcatccagt cactgctaag gcttacgata ttccagaaac gtatgtggct
     8941 gagctcaacc tttcagtcat cgaagctgcc cttcaacctg ctgctccatt tgtggaaatc
     9001 acgaaattcc cagcagtcag ccgtgacgtt gcccttctcc tcaaggcagc agtaactcac
     9061 caagaagtta tagatgctat ccaagctgcc ggcgtgaaac gtttgacaga tatcaaactc
     9121 tttgacgttt tctcaggtga gaaattggga cttggtatga agtcaatggc ttatagcttg
     9181 accttccaaa atccagaaga cagcttaacg gacgaagaag tcgcacgcta catggaaaaa
     9241 atccaagcat cgcttgaaaa aaaagtgaac gcagaagtgc gttaaacgat agtaggatac
     9301 aaattccccc tctagtttat gaacactaga ggggtgattt tatataatac tcaatgaaaa
     9361 tcaaaaagca aactaggaag ctagccgtaa gctgtacttg agtactgtaa ggcgaggctg
     9421 acgtggtttg aagagattgt cgaagagtat aaaataatta aaatgtgatt tctgtaaaaa
     9481 tacatctatg atcagagttt tgaaaactta caatgtctaa atctttaaca tagtagtggt
     9541 ttttaggcaa taaaatatga tctattgttg cattaaaaag ttttggactt tggctattcc
     9601 aagttcctct ttcaaaaggt ggtagtacat ttaatgcgtc cctatgagag cttatttttg
     9661 caagtgctcc atgacgcata gttgcattaa aatcatctgc aataatagcc tttggatatt
     9721 ttgaagccaa ttgattatga atgatgttta agtcttgctt ccagatttcc attaaacctg
     9781 gcagaggagg agcagtatgc aaggcaatga tatctggtat attttgtttt ctcgaatgta
     9841 atacaattgt cccgaaccgt gttgtatgaa aagttttagc ttctgtatag aaaccataac
     9901 ttttcttgac aatcacagtc acaggagcta ttccactatt ggtaggtgga gaagtgaaaa
     9961 tatcatagtt ggccatagaa agtccaactt gatgaaacaa tagtttgatt ctctggtttt
    10021 cttgctcacc tctgatattg gtagctagtt cagggaatat agccatatcg gcgtcaaaat
    10081 ggctaaaaat tcgctcaata tgttgtgctt ctatttgatt agcgacgttc caagttacta
    10141 attttaaggt tttagtctta tttgatgcag aagaaagggt tttatctgtt ccgaataata
    10201 gtaatatgag cgatagtaag agcaaaatgc cagagtaaaa ccgtatttgt ttatttttct
    10261 tgtaaaaaga tagggaaaaa aatacgaaac ttaaaatagc agccatagtt gcagtagcta
    10321 aggggaaggc ataaatctgt gccaagatag gtctggtaga tagccaaata ttaagattag
    10381 aagatggaaa aaaagaataa gttatgatag ggataacaaa gagaatgacc gaaagggcag
    10441 agagaaatgt tttaatcatt gtgtgagtac ctcaatttgc aatggttgct cggagctaat
    10501 gtgactttgt gactttactt gattgatatt ctttttcttg tcttcctcat agattaagta
    10561 caacccaagt aaaaaaagtc caatttaaga ttgaaatgat taaaaggcac agaaatgcaa
    10621 gacaattata ctacaaaagg caaacatttg acaatcgata gccgtcgctt aatcgaaaga
    10681 tggaaaaaag aagggaaatc aaatagagaa attgcctctc tgcttggaaa agttcctcaa
    10741 actatccaca ctgaaatcaa gcgt
//
LOCUS       DAVBCA010000066        10086 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.066, whole genome shotgun sequence.
ACCESSION   DAVBCA010000066 DAVBCA010000000
VERSION     DAVBCA010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10086)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10086)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10086
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.066"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            588..986
                     /locus_tag="VQU19_001797"
     CDS             588..986
                     /locus_tag="VQU19_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HET2481005.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEVGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKKQTVFLILQQ"
     gene            1024..1713
                     /locus_tag="VQU19_001798"
     CDS             1024..1713
                     /locus_tag="VQU19_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2481006.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQLTLIVQNYWQFSSQIGNFV
                     WIQNILSLLFIGVMIVVLVKTGHGYLFRIPRKKWLWYSILTVLVVVFQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYIALFFLVPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFVFATVGIIFAGLTRYTKSIYPSYAVHVINNIVATFP
                     FLLTFLHRVLG"
     gene            1755..2003
                     /locus_tag="VQU19_001799"
     CDS             1755..2003
                     /locus_tag="VQU19_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2481007.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLKWFVLERLELKDDA"
     gene            2033..2644
                     /locus_tag="VQU19_001800"
     CDS             2033..2644
                     /locus_tag="VQU19_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2481008.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGGFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMFYNSWPLLYYL"
     gene            2805..3599
                     /locus_tag="VQU19_001801"
     CDS             2805..3599
                     /locus_tag="VQU19_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HET2481009.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            3596..4231
                     /gene="trmB"
                     /locus_tag="VQU19_001802"
     CDS             3596..4231
                     /gene="trmB"
                     /locus_tag="VQU19_001802"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HET2481010.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            4357..4836
                     /gene="rimP"
                     /locus_tag="VQU19_001803"
     CDS             4357..4836
                     /gene="rimP"
                     /locus_tag="VQU19_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HET2481011.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEIISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            4880..6016
                     /gene="nusA"
                     /locus_tag="VQU19_001804"
     CDS             4880..6016
                     /gene="nusA"
                     /locus_tag="VQU19_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HET2481012.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            6038..6331
                     /locus_tag="VQU19_001805"
     CDS             6038..6331
                     /locus_tag="VQU19_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HET2481013.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            6324..6623
                     /locus_tag="VQU19_001806"
     CDS             6324..6623
                     /locus_tag="VQU19_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HET2481014.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            6640..9432
                     /gene="infB"
                     /locus_tag="VQU19_001807"
     CDS             6640..9432
                     /gene="infB"
                     /locus_tag="VQU19_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HET2481015.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     VKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            9683..10033
                     /gene="rbfA"
                     /locus_tag="VQU19_001808"
     CDS             9683..10033
                     /gene="rbfA"
                     /locus_tag="VQU19_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HET2481016.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
BASE COUNT         3060 a         1847 c         2301 g         2878 t
ORIGIN      
        1 attcaagatt tggatgaaaa attttaaaaa acaatgatat actaaacttg tcaaagttgc
       61 aacgggtgct gctacattat gttaaaaatc gctcttgatt gataagctgg atttgttagg
      121 aaaggagtaa ataattatgg ataagaaaaa gatagtttcg actataatat gtatagtatt
      181 tcttgtagtg tcagtagata atttttttag agacttaacc ccgttactgt tcattttaaa
      241 tattattggc ctgtcttgct tttcagtgct aacatacatt aacataaaag agatactctt
      301 aaatataagt aaatgatgat ttggttagtc ctagaaccaa tcaacttatg tttatcggct
      361 tggcagattt tatgtttgtc atttgtttgt atagaggtat ttcagaaaca gaattctatc
      421 aacaactaat cgcttatata ggtgtattct ctgcttgttt atcacgcttc tgctcatgtg
      481 gggcttgaag tattataaaa agtagctttc tatccttttc tgacaggata tttgagtaga
      541 aggctctatt aaattgttag tgaaataaat gaatggaggt atttaatatg aaatacagat
      601 tattttttgt tattttcttg agtagtgtgt tggatattct tttagggaca tttttacaaa
      661 tctctatcgt atctattggg tggcttgttc tttacagtgg tttgtttgaa gtaggagttt
      721 tccttcttgc taataaaggg gtggcggtaa aaatcaagga agtagatatt cgaaatcgct
      781 ttaaatttat ttttggaaaa accttatggt ttcaaattct tttgctcatc tttttgataa
      841 tcaaacttta tcttggtttg gatgcgaggt tgattttatt ctatggacat attttcattg
      901 tctttaatgc cttaatgtat ctattatcta gtagtcaggt tagccttaaa aaaaaacaaa
      961 ctgtcttctt aatcttacag cagtagagtc tgacaaggtg aggtcatagt agggaggatt
     1021 tctatgaaaa agtatcaact tctattcaaa ataagtgcag tcttctctta cttatttttc
     1081 gtatttggtc tttctcagct gacgcttatc gtccaaaatt attggcaatt ttcttcccag
     1141 attggtaatt tcgtctggat tcaaaatatc ttgagtttac tttttattgg agtcatgatt
     1201 gtggttcttg ttaagacagg ccatggttat ctcttccgca ttccaagaaa aaaatggctt
     1261 tggtattcga ttttgacagt attagtggta gtgttccaga tctcttttaa cgttcagaca
     1321 gctaaacatg ttcagtcaac tgcggaaggt tgggctgtat tgattggtta tagtgggact
     1381 aactttgcag agctaggtat ttatatagcc ctgttctttc tggttccact gatggaagaa
     1441 ttgatttata gaggattact gcaacatgct ttctttaagc attcgcgatt tggtcttgat
     1501 ttgcttcttc cttctatttt atttgctctc cctcattttt caagcctgcc tagtctgtta
     1561 gatatcttcg tctttgcaac agttggaatc atctttgctg gtttgacccg ctataccaag
     1621 agcatttatc catcctatgc ggtgcatgtg atcaataata ttgtagcgac cttcccgttt
     1681 ttgctcactt ttctacatag ggtcttgggg taaaaaaaca aaaggcttgc ttttcagcca
     1741 tagaggaggt catcatgtat aaacacttat ttttcctaga ttccaaaact ttagatcggt
     1801 tgacacccta tattctagtc ttggcttctg acaccattgc ttttaatgtt tttgtgctaa
     1861 cctttgtatc tgcggtggtt tttaatttcc taaattccat gctagcttta atggctatat
     1921 tcataggggc tggctatgtg gtcggatttt ggttgctaaa atggtttgtt ttggaaaggt
     1981 tagagctaaa ggatgacgcg taggaagtct gtttggtgag gaggatagtt ttatggagtt
     2041 ttttgataaa tttcatgcct tgtgttttgg atttttagta ctaataattg tcattacagt
     2101 tccttatacg attaaccatg ggggtttttt tcaaaatgaa tctgcattga ttcttgtaag
     2161 tcttcttgta acctcgctga gtgttgctta tgctagaaag tttgaaatga tttcttttgg
     2221 gatgttaagc aagaaacaac ttttgctttt cattgcaatc tttcttctaa gtgtacttga
     2281 gacgctggtt tatattcatt tcttcgctgt ttcttctggc tcaggggtcc aacacttggc
     2341 ggaagtcagc agaggaattt ccctgtcttt gattttgact acctcagttt ttggccccat
     2401 ccaggaggaa ctcattttca gaggacttct tcaaggtgcg gtttttgaca attcttggtt
     2461 agggcttgtg ctaacttcct ctctcttttc tttcatgcat ggaccttcta atgtcccttc
     2521 gtttattttt tatctacttg ggggtttgtt gctgggcttt gcttataaaa agagtcaaaa
     2581 cctatgggtt tctactctag tacacatgtt ttacaacagt tggccactcc tatattattt
     2641 ataaaaatta tgaaaaggta agcagaagac ggtgcttacc tttttcaagc tataatgata
     2701 cccaagccaa tccagaggct tttctttgag aatcgggtta gagtggttga cgaataggcc
     2761 aaaaactagt agaatagtaa ggaaacttta tacggaggaa agaaatggat ttgggtgata
     2821 atgagctaac actgactccc atacctggga aaagtggcaa ggcttatatg ggtagctatc
     2881 ctgacgggaa gcgcatcttt gtaaaaatga acacctctcc aatcctacct ggtctagcta
     2941 gagaacaaat tgctccacaa ttattatgga gtcgtcgttt ggcagatggg cgtgatatgt
     3001 gtgctcaaga atggttgaca ggcaagatat tgacccccta tgatatgaat cgtaagcaaa
     3061 tcgtcaatat tttaacccgt cttcatcgct cacgtccgtt gatgacacaa ttgagtcgtt
     3121 tgggctatgc catggaaaca cctgtagatt tactacagtc ttggcaggaa acggctccag
     3181 atgctttgcg taaaaatcat tttatcagtg aagtgatggc tgatttacgt cagactattc
     3241 caggatttag agaggaccat gcgaccattg tccatggaga tgtacgacat agtaattgga
     3301 ttgagacaga tagtggcttg atttatttag tagattggga ttcggttcgc ttgaccgatc
     3361 gcatgtttga tgtggcccat atgctctgcc attatatttc agaacatcag tggaaggaat
     3421 ggttgaccta ctacggttac aagtacaatc aaacggtatt aagtaaattg tattggtatg
     3481 gtcaattgtc ttatttgagt cagatttcca agtattatat gaaccaagat ttagaaaatg
     3541 tcaatcggga gattcatggt ttgcgtcatt tccgagacaa gtatggaaag agaagatgag
     3601 agttagaaat cgtaaagggg caacagaatt actagaggca aatccccagt atgtggtcct
     3661 caatcccttg gaagccaagg caaaatggcg ggacttgttt ggcaatgata atcccattca
     3721 tgtggaagtt ggaagtggaa agggtgcctt tgtttcaggt atggccaagc aaaaccctga
     3781 catcaactat atcgggattg atattcaaaa gtctgttttg agctacgctt tggacaaggt
     3841 gcttgaagtt ggagtgccta acatcaagct cttgtgggta gatggttctg acttaactga
     3901 ctattttgaa gacggtgaga ttgatcgctt gtatctgaac ttttcagatc catggccgaa
     3961 aaaacgccat gaaaagcgtc gtttgaccta caagaccttc ttggatacct tcaaacgtat
     4021 cttgcctgaa aatggagaaa ttcatttcaa gacggataac cgtggcttgt ttgagtacag
     4081 tttagtgagc ttttctcaat atggcatgaa actcaatggt gtctggttag atttgcatgc
     4141 cagtgatttt gaaggcaatg tcatgacaga atacgagcaa aaattctcaa acaaggggca
     4201 agttatctac cgagttgagg cagaatttta agagatagcc taaaattagg ctgtacaagt
     4261 gcttttgctt tacataagtt ggcaaacgtg ctatactgat agtaagaata tgaaaagtga
     4321 ggcggggaaa tatcttcgcc tcttgcttat gaggaggtgg acgcaatcgc aacaatcgta
     4381 gaattagtca gagaagttgt agaacctgtc atagaagctc cttttgaact cgtggatatc
     4441 gagtatggaa agattggcag tgacatgatt ctcagtattt ttgtagataa acccgaagga
     4501 attaccttga acgacacggc agacttgaca gaaattatca gtcctgtcct agacaccatc
     4561 aagccagatc ccttcccaga acaatatttc ctagaaatta ccagtccagg tttggaacgc
     4621 cctttgaaaa ccaaggatgc cgtcgctgga gcggttggaa aatacatcca tgtcgggctc
     4681 taccaagcca tcgataagca aaaggtcttt gaaggaacct tgttggcctt cgaagaggac
     4741 gagttgacta tggaatatat ggacaagacg cgtaagaaaa ccgtccaaat tccatacagt
     4801 ttagtatcaa aagcacgttt agcagttaaa ttatagaaaa agaaaggata gcttttgagg
     4861 attcaaaagt gaagaaaaca tgagtaaaga aatgctagag gccttccgca ttttggaaga
     4921 agacaaggga atcaaaaaag aagatatcat cgacgcagta gtagagtcgc ttcgttccgc
     4981 ttatcgcaga cgctatggtc agtcagacag cgtagctatt gacttcaacg aaaaaacagg
     5041 tgactttaca gtttatactg tccgtgaagt tgttgatgaa gtatttgata gccgtttgga
     5101 aatcagcttg aaagatgctc ttgccattaa ttcagcttat gaacttggag acaaaatcaa
     5161 gtttgaagaa gcaccagctg agtttggtcg tgtagcagcc cagtctgcca aacaaaccat
     5221 catggaaaaa atgcgcaagc aaacacgtgc catcacttac aatacttaca aagaacatga
     5281 gcaagaaatc atgtctggta cagtagaacg ctttgacaac cgctttatct atgtcaacct
     5341 tggtagcatc gaagcccaat tgtcaaaaca agaccaaatt cctggagaag tttttgcttc
     5401 tcatgatcgt atcgaagttt atgtttacaa ggttgaagac aaccctcgtg gtgtgaacgt
     5461 ctttgttagc cgtagtcatc cagaaatgat caaacgttta atggagcaag aaattccaga
     5521 agtttatgat ggaactgttg aaatcatgag cgtggctcgt gaagcaggtg accgtacgaa
     5581 ggttgctgtt cgtagccaca atccaaacgt ggatgctatc ggtacaatcg ttggacgtgg
     5641 tggtgctaat atcaagaaga ttactagcaa attccaccca gctcgttacg atgctaaaaa
     5701 tgaccgcatg gtaccaatcg aagaaaatat cgatgttatc gagtgggtag cagatccagc
     5761 tgaatttatc tacaatgcca tcgctcctgc tgaggttgac caagttatct ttgatgaaaa
     5821 cgacagcaaa cgtgccttgg tggttgttcc agataacaag ctttctcttg ccattggtcg
     5881 tcgtggacaa aacgtgcgct tggcggctca cttgactggt taccgtatcg atatcaagtc
     5941 tgctagcgaa tttgaagcca tggaagacgc tgcttcagta gagttggaag tagaaaacga
     6001 tactgtagaa gaataaaagc tgctagagga gggaaagatg aaaacaagaa aaatcccttt
     6061 gcgcaagtct gttgtgtcta acgaagtcat tgataagcgt gatttgctcc gcattgtcaa
     6121 gaacaaggaa ggacaagtct ttattgatcc tacgggcaag gccaatggcc gcggcgctta
     6181 tatcaaacta gacaatgcag aagccctaga ggcgaaaaag aagaaggtct ttaaccgcag
     6241 ctttagcatg gaagtggaag aaagctttta tgacgagttg atcgcttatg tggatcacaa
     6301 agtgaaaaga agagagttgg gacttgaata agcaaaagat aagtaatctc ttggggcttg
     6361 ctcagcgagc agggcgcatc atatcgggtg aagaattggt ggtcaaggcc attcaagacg
     6421 gcaaggccaa gttggtcttt ctagctcatg atgctggacc caatctgacc aagaagattc
     6481 aagataaaag tcattattat caagtagaaa ttgtaaccgt gttttcaaca ctggaattaa
     6541 gcatagcagt cgggaaatcg agaaaggttt tggctgtaac agatgctgga tttacaaaga
     6601 aaatgaggtc tcttatggaa tagaagagga ggacatgatt tgtctaagaa aagattgtac
     6661 gaaatcgcaa aagaacttgg aaaagaaagt aaagaagttg tagcgcgtgc aaaagagttg
     6721 ggcttggatg tgaaaagcca ctcatcaagt gtggaagaag ctgtcgctgc aaaaattgct
     6781 gccagcttta agcctgcagc tgctccgaaa gtagaagcaa aacctgcagc accaaaagta
     6841 agtgcagaaa agaaagccga aaaatctgag ccagctaaac cagctgtagc taaggaagag
     6901 gcaaaaccgg ctgagccagt tgctccgaaa acagaaaaag tagcagtgaa accgcaaagt
     6961 cgtaatttca aggctgagcg tgaagcccgt gctaaagagc aggcagaacg acgcaagcaa
     7021 aataagggca ataaccgtga ccaacaacaa aacggaaacc gtcagaaaaa cgacggccgt
     7081 aatggtggaa aacaaggtca aagcaaccgc gacaatcgtc gctttaatga ccaagctaag
     7141 aagcagcaag gtcagcaaaa acgtagaaat gagcgccgtc agcaagagga taaacgttca
     7201 aatcaagcgg ctccacgtat tgactttaaa gcccgtgcag cagccctaaa agcagagcaa
     7261 aatgcagagt acgctcgttc aagtgaggaa cgcttcaagc agtatcaggc tgctaaagaa
     7321 gccttggctc aagctaacaa acgcaaggaa ccagaggaaa tctttgaaga agcggctaag
     7381 ttagctgaac aagcacagca agttcaagca gtggttgaag tcgtccctga gaaaaaagaa
     7441 cctgcagtgg atacacgtcg taaaaaacaa gctcgaccag acaaaaatcg tgacgattat
     7501 gatcatgaag aagatggtcc tagaaaacaa caaaagaatc gaagtagtca aaatcaagtg
     7561 agaaatcaaa agaatagtaa ctggaataac aacaaaaaga acaaaaaagg caataacaag
     7621 aacaaccgta atcagactcc aaaacctgtt acggagcgta aattccatga attgccaaca
     7681 gaatttgaat atacagatgg tatgaccgtt gcggaaatcg caaaacgtat caaacgtgaa
     7741 ccagctgaaa tcgttaagaa acttttcatg atgggtgtca tggccacaca aaaccaatcc
     7801 ttggatgggg aaacaattga actcctcatg gtggattacg gtatcgaagc caaacaaaag
     7861 gttgaagtgg ataatgctga catcgaacgt ttctttgtcg aagatggtta tctcaatgaa
     7921 gatgaattgg ttgagcgtcc accagttgtt actatcatgg gacacgttga ccacggtaaa
     7981 acaacccttt tggatactct tcgtaactca cgtgttgcga caggtgaagc aggtggtatt
     8041 actcagcata tcggtgccta ccaaatcgtg gaaaatggta agaagattac cttccttgat
     8101 acaccaggac acgcggcctt tacatcaatg cgtgcgcgtg gtgcttctgt taccgatatt
     8161 acgatcttgg tcgtagcggc agatgacggg gttatgcctc agactattga agccatcaac
     8221 cactcaaaag cagctaacgt tccaatcatc gtagccatta acaagattga taaaccaggt
     8281 gctaacccag aacgcgttat cggtgaattg gcagagcatg gtgtgatgtc aaccgcttgg
     8341 ggtggagatt ctgaatttgt tgaaatctca gctaaattca accaaaatat cgaagaattg
     8401 ttggaaacag tccttcttgt agctgaaatc caagaactca aggcagaccc aacagtgcgt
     8461 gcaatcggta cggttatcga agcgcgcttg gataaaggaa aaggtgcggt cgcaaccctt
     8521 cttgtacaac aaggtacctt gaatgttcaa gacccaatcg ttgtcggaaa taccttcggt
     8581 cgtgtccgtg ctatgaccaa cgaccttggt cgtcgtgtta aagttgctgg accatcaaca
     8641 ccagtctcta tcacaggttt gaacgaagca ccgatggcgg gtgaccactt tgccgtttac
     8701 gaggatgaaa aatctgcgcg tgcagcaggt gaagagcgtg ccaaacgtgc cctcatgaaa
     8761 caacgtcaag ctacccaacg tgttagcctt gaaaacctct ttgataccct taaagctggg
     8821 gaactcaaat ctgttaatgt tatcatcaag gctgatgtac aaggttctgt tgaagccctt
     8881 tctgcctcac ttcaaaagat tgacgtggaa ggtgtcaaag tgactatcgt ccactcagcg
     8941 gtcggtgcta tcaacgaatc agacgtgacc cttgccgaag cttcaaatgc ctttatcgtt
     9001 ggtttcaacg tacgccctac accacaagct cgtcaacaag cagaagctga cgatgtggaa
     9061 atccgtcttc acagcattat ctacaaggtt atcgaagaga tggaagaagc tatgaaaggg
     9121 atgcttgatc cagaatttga agaaaaagtt attggtgaag cggttatccg tgaaaccttc
     9181 aaggtgtcta aagtgggaac tatcggtgga tttatggtta tcaacggtaa ggttgcccgt
     9241 gactctaaag tccgtgttat ccgtgatggt gtcgttatct atgatggtga actcgcaagc
     9301 ttgaaacact ataaagacga cgttaaggaa gttacaaacg gccgtgaagg tggattgatg
     9361 atcgacggct acaatgatat taagatggat gatgtgattg aggcgtatgt catggaagaa
     9421 atcaagagat aagatttttt gctcctttct taggtggtga gggacgcaag caaaccgatg
     9481 gtttcattgc ttatttttga gcctagggtc tcaaaaatcc cctgtgatgg gactgataaa
     9541 tcagttccat cactttcacc acggcgaaag aagcagatga cttcaaattg aacttcgttt
     9601 caatttaaac tgaaaatcaa gaagtttaaa atagctaggt ctgctggcct agcttttggt
     9661 tcaaagtaga gaaaggaata tcatggcaaa tcatttccgt acagatcgtg tgggcatgga
     9721 aatcaagcgt gaagtcaatg agattttgca aaagaaagtc cgtgatccac gtgtccaagg
     9781 tgtgaccatc acagatgttc agatgctggg tgacttgtct gttgccaagg tttattacac
     9841 cattttgagt aaccttgctt cggataacca aaaagcccaa atcgggcttg aaaaagcaac
     9901 tggtaccatc aaacgtgaac ttggtcgcaa tttgaaattg tacaaaatcc cagatttgac
     9961 cttcgtcaaa gacgagtcca tcgagtatgg aaacaagatt gacgagatgc tacgcaatct
    10021 ggataagaac taaagaagag gggttgcccc tctttttcgg ctctttgtca actgtagtgg
    10081 gttgaa
//
LOCUS       DAVBCA010000067        10041 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.067, whole genome shotgun sequence.
ACCESSION   DAVBCA010000067 DAVBCA010000000
VERSION     DAVBCA010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10041)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10041)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10041
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.067"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(17..1918)
                     /locus_tag="VQU19_001809"
     CDS             complement(17..1918)
                     /locus_tag="VQU19_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HET2481017.1"
                     /translation="MKEERRQFFERVDGNQCRDYILSHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWAYMLNRQEYLLQFMIGYVVEGDKDYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDMLEEKELEKIL
                     VSLEKQIDFMKSYYRAKYTLSNWGILQTIPMLAIYYFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYRELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEILSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     KRAWQPKSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHKRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSNKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDICVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            complement(1940..2233)
                     /locus_tag="VQU19_001810"
     CDS             complement(1940..2233)
                     /locus_tag="VQU19_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HET2481018.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQTEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIKDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            complement(2233..3051)
                     /locus_tag="VQU19_001811"
     CDS             complement(2233..3051)
                     /locus_tag="VQU19_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET2481019.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPAKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVVIGIIGSWLKIIA"
     gene            complement(3038..3817)
                     /locus_tag="VQU19_001812"
     CDS             complement(3038..3817)
                     /locus_tag="VQU19_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET2481020.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTANHVVEEEAHDDWI"
     gene            complement(3832..4323)
                     /locus_tag="VQU19_001813"
     CDS             complement(3832..4323)
                     /locus_tag="VQU19_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HET2481021.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLACNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNAPGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            complement(4334..5524)
                     /locus_tag="VQU19_001814"
     CDS             complement(4334..5524)
                     /locus_tag="VQU19_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HET2481022.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREATLKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSAQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            complement(5536..5964)
                     /locus_tag="VQU19_001815"
     CDS             complement(5536..5964)
                     /locus_tag="VQU19_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET2481023.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPVKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEDFESGI"
     gene            6235..7050
                     /locus_tag="VQU19_001816"
     CDS             6235..7050
                     /locus_tag="VQU19_001816"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HET2481024.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
     gene            7069..7710
                     /locus_tag="VQU19_001817"
     CDS             7069..7710
                     /locus_tag="VQU19_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HET2481025.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKDYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            7741..8742
                     /locus_tag="VQU19_001818"
     CDS             7741..8742
                     /locus_tag="VQU19_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HET2481026.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITIAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            8752..9381
                     /locus_tag="VQU19_001819"
     CDS             8752..9381
                     /locus_tag="VQU19_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HET2481027.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYITLR"
     gene            complement(9760..10041)
                     /gene="tnpA"
                     /locus_tag="VQU19_001820"
                     /pseudo
     CDS             complement(9760..10041)
                     /gene="tnpA"
                     /locus_tag="VQU19_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028215.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
BASE COUNT         3004 a         2227 c         1834 g         2976 t
ORIGIN      
        1 ttcaaaatgc ctatttctag cactgcaagc gaatcattct ctcatttatt ttatcatata
       61 ctagacattt tccacgcatt tttgttccgt caacgaggca caatttttca cctacacaaa
      121 tatcctcgct taataacaga atcagcttgt ctgtttcgtc atttttcact tcaaaagcca
      181 gagcattttc cacttcacga tcatctgtct ggtagacaga atgacggatg atttcaaaac
      241 tctcatgcgc aatgatggta taatccagca tctgattctc aaagaattgg cgcttggtga
      301 gtttgttact tctttcaagc tcattgtatt taggagaaat gatggtatct tccaaatcaa
      361 aatcaacttc actccatagt ctcaactgat tgattttccc atcttgatag gtcacatcct
      421 tgtcaaggat aaactgagtc aacgcctcat gctgaccttg acacctgatg tcatccacca
      481 agagccagac atcctctacc aacatgagga tttttctctt gtgaagataa ggcaaatcag
      541 gttctgctga ccaataagcc ccttcaatat aatgcactcc ctccctttct ttatggtgac
      601 aaaacaggga gtgaggatag tattcatatt cccaggatcc cgtgattctt tccggagctt
      661 tcccatctac aatgcaggtc gaatgactcc aagcactctt taagagataa cgttcatata
      721 tctcccgata agaataacgc ccagcatcta tgaaaatagg ttgtccttga tactgtaagc
      781 aaaaactatt ctcgtcacta tggctatggg cacttcctag cggaccattt ttgaaaaata
      841 gataacgatg ttcatcctta atgcagacat gtccagagtc ttcaaagatc atggacttag
      901 gctgccaagc tctcttttca aattcctgca gtcgcttgac cttttctcgc cccaggaaca
      961 agaggctaag caaatcgact ttaacatcca gaccgttaag aaggtcttcc ttgttcaaaa
     1021 ccacagcaga caggctcaaa atttctgtcg tttctgtaga atcgctatca ccaaaagcca
     1081 aagttcgtcc atctaagcct gtcatcattt gaatataggt cgccatcttt tccagcaact
     1141 ctcggtaact atcttgcaag tctggaagca agagacacaa atccagcaag gctttataaa
     1201 cctctacatg atagagaatc gactgttcaa actggcttcc atctcctaaa atctgtgtct
     1261 caatttgctg tttcaactcc tctgaagcaa aatggtaagc ttcttctagg tccatcttat
     1321 ctgaaaagaa ataatagata gcaagcatcg gaattgtttg taaaatcccc cagttactaa
     1381 gggtgtactt ggcgcgatag tagcttttca taaagtcaat ctgcttttct agactgacca
     1441 aaattttctc tagttctttc tcctctagca tgtcaaattt caagaggagc aagagtagtt
     1501 tcaaccaagt aaaggaacga atacccgtat ccaaggttct agtcatcaag gattgaggag
     1561 aaaattctct cacctgctca atccaatcaa atagaaagaa cttgcacttt tgaatatagt
     1621 ccttatctcc ttctaccaca taccctatca taaactgcaa gagatattct tgtcgattga
     1681 gcatataagc ccattctgga tcatcttcaa atacttgatc ccataccatc ggctggattt
     1741 gatggatttt tgaacaaggc tccatatccc aaggactatc aaacataaaa cgattgtcca
     1801 tcaagcgttc aagggaactc ttgactttct catagtcttt tgaacagtgc gacaagatat
     1861 aatcacgaca ttggtttcca tcgactcttt caaaaaattg tcttctttct tctttcatta
     1921 tctattacca gaaaaagaac tacttaaaaa gcagttcttt tgtctttccc attacacttt
     1981 ccttttctac atagatgacc acaccttttg caatctgcaa ggagaccaag tcatctttga
     2041 tagaaatgat ttttccatga attccagaca ataacaacac ttcatcacca gatgttaaag
     2101 aagctaaata ctcttgtcgt tgctccgtct gtttgcgaag caacttttgc tgacgaatag
     2161 aatgaaagct tgacagtaaa aggggactca ctgccaagac aatcactatt ccataaaaca
     2221 atgttgtatc cattaagcta taatcttaag ccagcttccg ataattccga tgacaactgt
     2281 taaaataacg agtttatatg ttgtccattt cttttctttg atcaagtagt aaactaaaag
     2341 tgtaaatagg gctggtagaa gagctggagc aaccttatca agcattccct gaatacttac
     2401 gatactttgt ttagcgtctg ctttaacttc ccctgcagca aaggtaatcg gcaccataat
     2461 cttaacagat gtcgctgcca aaccagcaat tacggttaca ccgataatat tggcaatacg
     2521 agaaatcgtt gccatctgtt cgcttagttt atcaatcaca gttgttccta gtttgtatcc
     2581 atacagacca gttgacaatt taatcgctgt taaaatcgta ttcatcgcaa ggaagaacaa
     2641 gattggaccg acaaccaagc cttcttgagc aaacgaagct gcgatggttg agaacaatgg
     2701 agctaaacag aattgagaaa gagaatcccc aatacctgcc aatggtccca tcaaggccat
     2761 cttgatgcta cgtgtttctt ttgccggacg gccattttcc aacattacaa gatgcaagct
     2821 ggtaataaaa ggcaggaagt gtgggttggt attatagaat tcacagtttt cttccaaggc
     2881 ttggtagaaa ccttcctgat cctctccata gtgttttttc aaagcaggat acatcacatt
     2941 ggcatatccc aacccttgat agttactata gttaaatcca ttttgacaaa agaatgcccg
     3001 caaagacgtt ttaagataat cacgttttgt taatttgtta gatccagtca tcgtgtgctt
     3061 cctcctctac cacatgattc gctgtttttg gcttgttata aaattcaatc aaagcaaaga
     3121 tagtacctac aattgcaata ccaattgttg ggatgtttag ataagctgca caaacatatc
     3181 ccaacaagac aaagggaatc aactctttct tagccatcac tgacaagatc atcgcaaaac
     3241 cgatagctgg gagcatttta ccagcaactg tcaaacctgt aagtaatacc ggtggaatgt
     3301 agtctacgag tttcaacaag gtatccattg aaagggcacc caagcaaccc aaggtaaatc
     3361 caataaaggc aaacaaccaa attgttgcat ttagagtaaa cttgaatttc ttcaaattat
     3421 ggtttttcaa gtgcttcatc gccgtttcag gcgcaccagc acgtacagtg taggcgaaag
     3481 tttgtaagaa ttgaatcgcc acagcaatcg gagtagagag ggcaagagcc gcttctggac
     3541 tgactttacc agcactagtg atagccatca aggtaccaaa gataccaggt ccgattgggt
     3601 ttggtggaac agtacctcca gcaccaacac cgaatcccat ataagccaat tcaccaatag
     3661 ctcccattgc aagagcagta ggcagatcac ctagaataat tccgacacca aatgacagaa
     3721 caatacatct attggtgtaa attcctaaca gcattccact aaaacagaaa gctgtccata
     3781 atccaattaa aatcgcttga aatacattaa tcgacataac gatctcctct tttaaatata
     3841 gtccataatg ttgacttgaa cagctccatc atttcctgtt ggagttgttt tcgtattaaa
     3901 tgttacttga tgagtttggc ttaattcctt gagggctgcc ttgtcctctt cacccaggaa
     3961 gatggagcgt gtcacttgct ctttaccagg ggcattgtga atgttcccaa tattgatttc
     4021 tttgataggg acaccacctt ctaccaaggt taaagcgtcc tttacatcct ttacaacgat
     4081 aaagatcgtt tgagcaggat tagccttgtg aatgatatca atcacctttt gcaaagggaa
     4141 gaaacgcatg gcaactgagt ctggcacaac tgttttcatc agagtttgtt gcatcttgtc
     4201 cgtgcttact tcgtcattgg caacaatgac cgtattacaa gctaggtatt ttacccaaag
     4261 ttgtccttgt ccatgaatca accgttcatc gatacgggtc ataataatat ttggcattgt
     4321 catatttctc ctcctaccaa tataggttcc agtctttgta gaaacggata agggcttcta
     4381 ggtaatagta gtcaccccag atattgcctt catccactcc tttacctgaa tgccatgagt
     4441 acacaccgtg gagaagactt gtcccaccag gggtaaattg atcatttgca taatgttcga
     4501 tcaaggaacg aagcatggca tgcatagcat gtttataaat atctttgtca gcatccacct
     4561 ctgggagatg ttttagcatt tcatgaatcc cacagacggc gatagctgtt gctgaagaat
     4621 ctcgtgattg agcactacca tcattaaaaa tcaaatccca ataggacaca tgatcttttg
     4681 gcagacgatt caagaaataa ttggtcacac ccttaaacaa gtcaaagcag gactcgtctt
     4741 ttaagtgacg ataagtcaaa ggaataccat agactcccca tgattgacca cgtgcccagc
     4801 atgaatcatc actataccct tgtctcgtta cacctttaaa gggttgacct gtctcaggat
     4861 caaaatagaa ggtgtggaag gacgaagcgt catcacggat tacattatta gctgaagcat
     4921 agaaatgact ttctgcaata tcgtagtatt tttgatcgcc tgtttcttga taagcaaaga
     4981 ataagagttg gatattgagc aagcagtcga taatcaaacg gtaatgctct ttcttgccca
     5041 agtctcccca agcttgaata aaaccacctt tttcttgata gcgttcaatc aacttatctg
     5101 cagctttcaa ggttgcttct ctagcctctc catctccatt tatcttatat tcagccatac
     5161 aagacggtgt gtacaagaag ccgagatcat ggtgatccaa ttctactctc ttattgacac
     5221 gatccaggaa agaaagaaca tttttatgag cgatgttttt aaatgcatcc tgttgactgt
     5281 attcataagc caaccacagt tctcctgtcc agaaaccatt ggtccattcc gtgttatcca
     5341 tgattggata gacattatca aaggtagctg gcgtcgggaa atcttccttg aaatagtcaa
     5401 ggttgagttc taactgccga ataaccttat cgattgcctg gccgacttct tctttcgtca
     5461 gaagtggtac ttctaagaag cgctcaggcg attttatttt ttcaatcgta acctttttta
     5521 tcattctttt accctttaaa tacccgattc gaaatcttct tcctctgcat ccgttgaaaa
     5581 caattcttta ccatttacga ctccgccctg ggccgccact actgatttat taacaacctc
     5641 atcaaagcta tgagccattc tagcaaagac tgcttccatt aacatggcta agttcaaacc
     5701 cgagagaaca ttcattgttt tgactggatt ttctcccatt atggtagaag aaaccttgaa
     5761 tggcgatcct cccaagagat cacttaggat taaaacttct tcttcatttg aaattgcaag
     5821 taagattttt tgcttgagtt catctgctga cattccttcc acaaagtcaa tcgcctccac
     5881 attttcttga ttacctgcaa tcaattgtaa agaactataa atccctgtag caaaatgtcc
     5941 atgccctaca agtacaattt tcatcttttc tcctttcttg tttaggttta ccggtttact
     6001 ttatattccc cattgtaatc ctttattttt atcttgtcaa tagttttttt aaaaaaatat
     6061 tagcgctttc attatctttt taaccatttt aataaacaga aatttcaaaa cattccgttt
     6121 ttcaggaaaa caaatctttt tataaataaa aatatttatt tattgacaaa accggtttgc
     6181 tagaatataa tttggttata gagaagtctt aacaaatttg aaaggaagta tcaaatgaca
     6241 aatacatcat tctcaattga gcagttttct ttaaaaggaa aaattgctct catcaccggc
     6301 gcttcttatg gaattggatt tgctattgcc aaatcctacg ctgaagccgg cgctactatt
     6361 gtctttaacg atatcaatca agatctggtc aataaaggga ttgaagctta tcgtgaagtt
     6421 ggcatcgaag cccatggata tgtctgtgac gtgacagacg aggacggtat ccaagccatg
     6481 gtcaagcaaa tcgaacaaga ggttggtgtc attgacatcc tcgttaataa cgctggtatt
     6541 atccgccgag ttccaatgtg cgaaatgagc gccgctgatt tccgtaaggt catcgatatt
     6601 gacttaaacg caccatttat cgtttcaaag gcagttattc cttctatgat aaagaaaggg
     6661 catggaaaga ttatcaatat ttgttcgatg atgagcgaac tgggacgtga aacagttagc
     6721 gcttatgctg ctgctaaagg gggcttgaaa atgttgaccc gcaacattgc gtctgaatac
     6781 ggtggagcca atatccaatg taacggaatt ggaccgggtt atattgccac tcctcaaaca
     6841 gcacctcttc gtgagttgca agaagatggt tctcgccacc catttgacca gttcatcatt
     6901 gcaaaaacac ctgctgcacg ttggggaaat cctgaagatt tgatgggccc tgctgtcttt
     6961 ctcgctagtg atgccagcaa ttttgtcaat ggccacatcc tatatgtaga tggcggtatc
     7021 ttagcctaca tcggaaaaca acctgagtaa aaatagaaag aagatcttat gaaaatcgca
     7081 ttaatcaatg aaaatagtca agctagcaag aatcacatta tttacgatag tctaaaagaa
     7141 gcgacagata aaaaagacta ccaattattt aactatggta tgcgtggaga agaaggagaa
     7201 agtcaattaa cttatgtgca gaacggacta atggctgcca tccttttaaa tacaaaggca
     7261 gttgactttg ttgttaccgg ctgtggtacg ggtgtagggg ctatgcttgc tttaaacagc
     7321 ttccctggtg ttgtctgtgg tctagcagtg gacccaactg acgcttacct ttattctcaa
     7381 atcaatggtg gtaacgcctt gtctatccct tatgccaaag gatttggctg gggggcagaa
     7441 ctgaccctca aattgatgtt tgaacgctta tttgctgaag aaatgggcgg tggctaccca
     7501 agagaacgtg taatccctga acaacgcaac gctcgtatct taaacgaggt gaaacaaatc
     7561 acccacaatg atttgatgac catccttaaa acaatcgacc aagacttcct caaagacacc
     7621 atctctggca aatacttcca agaatacttc tttgaaaact gccaagatga tgaagtcgct
     7681 gcttatttga aagaagtatt agccaagtaa agctattcta aaccagaaag gaactaatgg
     7741 atgacgaaaa tattactgtt tggcgaacca ttaattcgaa tctcaccatt agatgccacc
     7801 agtatcggcg atcatgttgc cagttcgact tattttggcg gatcagaaat taacatcgct
     7861 tgtaatttgc aagccctggg tatctcaacg aaagtcttta ccgcactccc tgccaacgag
     7921 attggagatc gttttctcac attcttgaaa cagcaccaaa tcgataccag ttcaatctgt
     7981 cggcttggcg atcgaatcgg cctctactat ttggagaacg gctttggttg tcgtcaaagt
     8041 gaagttttct acgatcgtaa gcatacgagt atcagccaga ttcggccaaa catgctagat
     8101 atggattctc tctttcaggg gattagccat tttcatttta gtggaatcac catagctatc
     8161 ggtcaagagg tccgtgcgat ccttctccta ctcttggaag aagccaagcg ccgaggaatt
     8221 gtcgtttcaa tggatctcaa tctgagaaca aagatgattt cagtcctaga agccaagtat
     8281 gaattttcta agtttgcacg ttttactgac tattgcttcg gtattgatcc tctcatgatt
     8341 gatgaccaaa atctagagat gtttccaaga gacagtgcta gcctagaaga ggtggaaaat
     8401 cgcatgcgac ttttaaaaga agcctatggt ttcaaggcca ttttccatac cctccgatct
     8461 agtgatgagc aagacaaaaa tgtctatcaa gcctatgctc tggaagaacg atttgaagag
     8521 tctgtccaac taaaaactgc agtctatcaa cgaattggta gcggggatgc ctttatatct
     8581 ggtgcccttt accaactact ccatcattcc tccctaaaaa ctaccattga ctttgcagtt
     8641 gcgagcgcaa ctctcaaatg cactcttcca ggagaccatc tctccacttc cgcaactagt
     8701 attgaaaatt tactggcaaa tgcacaagat atcattcgtt aggagaatta catgaccaaa
     8761 tcagatacga ttattgaact aaaaaaacag aaaattgtcg ctgtcattcg aggaaataca
     8821 aaggaagaag gactacaagc ctcgattgct tgtatcaagg gcggtatcaa agctattgaa
     8881 atcgcctata ccaatcagta tgcaggacaa atcatcaagg aacttgtaga cttgtatcag
     8941 gacgatcaga gtgtttgtat cggtgcaggt actgtgcttg atgccgtaac tgctagagat
     9001 gccattctag ctggagcaaa ttacgttgtt tctccatctt tccatgctga aactgcgaaa
     9061 atgtgcaatc tctacagcac accgtacatt ccaggctgta ttaccctcac agagatcacg
     9121 actgcacttg aagccggtag tgaaatcatc aaactcttcc caggtagtac tctcagtcca
     9181 gcatatatct ctgcagtcaa ggcaccgatc ccacaagttt ccgtaatggt aaccggagga
     9241 gtcggcctaa acaacatccc tcaatggttc gctgctggtg cagatgccgt tggaattggt
     9301 ggcgaactca ataaactcgc ttcccaaggc aactttgacc gcatcagcga gattgcccaa
     9361 cagtatatta cactcagata aaatcataac tacccgtcta acgggtggtt tatcccagag
     9421 ctataagccc aaatcatcag ccagcgccta aagacgctgg cttttacgtt gttcaagcct
     9481 tattgctctt gactcgtcac ttgcctcttt aagagacttt ggtattactt accactatcc
     9541 ctaaagggat cctcatattc ttttacactc aatttatcta gtgctatagt agattgaaac
     9601 tggaatagta tacctctact tctaaaacat tgttaaaaat cgatttgact gtcctgatcg
     9661 attttgtcct gttcttattt cattttacta tatatcatac tttactagtt ctcaaatttt
     9721 catactcgtg aagaaatcat ccactggata atttctttaa tcttgactat atttcttaat
     9781 tgtggcttca ttaagcccta ctggacttac ataataacct tccacccaga aatgccgatt
     9841 cccaaacttg tacttgagat tggcgtgttt gtcaaacatc atgagtgcac tttttccttt
     9901 taaataaccc atgaaactcg aaacacttag ccttagtgga atactgacta acatgtgtac
     9961 atggtctggc attaagtgac cctcgatcat ttcaacacct ttataactac acaagcgatg
    10021 aaatatttcg cctaaactac t
//
LOCUS       DAVBCA010000068         9999 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.068, whole genome shotgun sequence.
ACCESSION   DAVBCA010000068 DAVBCA010000000
VERSION     DAVBCA010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9999)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9999)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9999
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.068"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(108..2213)
                     /locus_tag="VQU19_001821"
     CDS             complement(108..2213)
                     /locus_tag="VQU19_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET2481028.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELERKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQEKVIGQDKAVEVVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVVIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
     gene            complement(2822..3802)
                     /locus_tag="VQU19_001822"
     CDS             complement(2822..3802)
                     /locus_tag="VQU19_001822"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HET2481029.1"
                     /translation="MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNMGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDMLSVFGYQVHLGIFYIVFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLSFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            complement(3804..6056)
                     /gene="pbpX"
                     /locus_tag="VQU19_001823"
     CDS             complement(3804..6056)
                     /gene="pbpX"
                     /locus_tag="VQU19_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HET2481030.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDSFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAVYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKVEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            complement(6060..6377)
                     /gene="ftsL"
                     /locus_tag="VQU19_001824"
     CDS             complement(6060..6377)
                     /gene="ftsL"
                     /locus_tag="VQU19_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HET2481031.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            complement(6389..7339)
                     /gene="rsmH"
                     /locus_tag="VQU19_001825"
     CDS             complement(6389..7339)
                     /gene="rsmH"
                     /locus_tag="VQU19_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HET2481032.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNHYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            7505..7699
                     /locus_tag="VQU19_001826"
     CDS             7505..7699
                     /locus_tag="VQU19_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2481033.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            7715..8257
                     /locus_tag="VQU19_001827"
     CDS             7715..8257
                     /locus_tag="VQU19_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HET2481034.1"
                     /translation="MKKETFTEKLIKRTYGISGPLDEYKRREADSIGNQVFIVLFYLM
                     IFGNLIPLLLAYKYPQEVALIYPPLILVIALIAAGYVTYQMKKTGITVIEPDMLNEKE
                     SKQLHYPGLKAGLFFGLWMFFITPLLSILIDEGQDYFHSLLTIRNGVSSILGSIFFGA
                     SIQFLISRRIAKTKKNQDED"
     gene            8268..8510
                     /locus_tag="VQU19_001828"
     CDS             8268..8510
                     /locus_tag="VQU19_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2481035.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            8521..8856
                     /locus_tag="VQU19_001829"
     CDS             8521..8856
                     /locus_tag="VQU19_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2481036.1"
                     /translation="MKSLARLLNIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(8966..9967)
                     /locus_tag="VQU19_001830"
     CDS             complement(8966..9967)
                     /locus_tag="VQU19_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET2481037.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
BASE COUNT         2876 a         2269 c         1785 g         3069 t
ORIGIN      
        1 attgaaactg gaataataca cttctactat acgacatgcc tgtcgtacct aaaaaggaac
       61 cagttttttt cagctggctc cttctttttt atcctcaaaa ttctatctta ggctttctca
      121 cgaataacca aaacgccatc ttccatatct gcttccagat gtttagcatc taaatgatcc
      181 aagtggaagt ctgtcacctt atcacgaatt tcttgttcaa ccacgcgacg gagaggacga
      241 acccccatga cttcgtcgta accttcttct gtgatataat ctttagccgc ttgactaact
      301 accaagtcaa tgtctttctt agccaaggtt tggttaactt cagccaacat caaatctaca
      361 atcttagaaa ggtcttcctt agtcaagtgt gagaactcga tgactgcatt aaagcggttg
      421 aggaattctg gacggaagaa gggtttcaaa cggtccatca attctggttt atccgcatct
      481 tctgtcaagt tggcttcata gccaaatcca gcatttgagg tcgcaataac gacagtattc
      541 ttgaagttta ctgtatttcc ttgaccatct gtcaaacgac catcatctag aacttggagg
      601 agaagggtaa taacttgagg atcagccttt tcaatttcat ccaagagaat gatagagtat
      661 ggattgcgac gaacacgttc tgttaaggta ttgctattgt catcataacc cacatagcct
      721 gctgttgtac caattagctt agaaacagct gtgcggtcac tgtattcaga catatccaaa
      781 cggataatcg catcctgggt tccaaacata tcgagtgcca attgcttagc aagctccgtc
      841 ttaccaaccc cagtagaccc tacaaagagg aagctgccga ttgggcgatt tccttcatca
      901 aaaccagcac ggttacgacg gatagcacga gctacaactt ctacggcctt atcttgacca
      961 atcacctttt cttgcaagcg atgagccata tctttcaaac gttcgatatc tgaagctccc
     1021 atttgcgata ctgggatacc tgtcattcgt tccacagatt cagccacatc gttgacactt
     1081 gcagtcactt tcatatcttc tgtgtggttt tcgattttcc tttccaattc tgcaatgcgt
     1141 gttttatagt ttagagctgc ttcaaaatct tctgcttcaa ctgctttttc ttgcttgtct
     1201 ttttccgttt cgatttctcg ttcaacagca tgcacatctg ttactggatg ttgagccgcc
     1261 aagtgagcag ccgttacatc gacaaggtca atagccttat ctggcaagct acgttgagga
     1321 atgtattgaa cagaataatc caccgctgct ttcaagactt cgtctggcaa gatgacattg
     1381 tggtgttgtt gatagaggtc acgaatgcct tgaagaattt taaaagtatt ctctgctgaa
     1441 ggagcattga ccttcacttc gttgaaacga cgagcaagag cagcattctt caagatggtg
     1501 ttacggtatt cgtcttgagt tgttgcccca atcactgtca attctccacg agagagagct
     1561 ggcttgagaa tatccgcaag tcctttagaa ccactgtctc caccagtgct accagcacca
     1621 agaatttggt gaatttcatc aaagaagagg ataatattcc ctgcttcttt cacttcattg
     1681 actaagtttt ggacattttc ttcaaagcta ccacggtatt gagtaccagc ctcaagacct
     1741 gagatatcaa tggaaataat ttccttgttc ttgatagcag caggaacatc tccgttcaca
     1801 atggcttgcg ctagaccttc gacaactgct gtcttaccaa cacctgcatc tccgaccaaa
     1861 acaggattgt tcttggtgcg gcgtgagagg atttcagatg tttcttgaat ttccttgttt
     1921 cgtccgataa caggatccaa cttgccctca cgcgcttctg ctgttaagtt tcgacctagt
     1981 tttgcaagga caccgtcttg tttcatacct gatgcctgtt gtggcatttg cacatcagtt
     2041 tctgcatttc ctggtaattg accagtcgca cgatagtgag caaattcctc aggtgtgact
     2101 tcgcgtccat taattaagta acggcgattt tcagaactat atcctcgcat accacccatc
     2161 aattggttaa ataaatcatc catgttatta aaattattaa agttgttatt catattcttt
     2221 acctcttttt gtttacttag ttatgattac tgatattgac tatctttgac cattgtttta
     2281 aaaaatttag actagctaga tcgctaccct acgtactatt tctggttttt ctttttcaag
     2341 caggagtaga ctatctttac ctctgaagat tgctagatga aacatagact cacctctttc
     2401 tattttactt taaataagtg ttctagtaag gctttcattt accttacgtt cataatatac
     2461 tacattggtc agaaaaggtc aagagttttg actttaactg accaatattt ttttacactc
     2521 ttcgaaaacc tcttcaaacc acatcagctt cgccttgtct acaacctcaa aacagtgttt
     2581 tgagctgact tcgtcagttc tatcaaccat ctcaaaactg tatagtaaaa tgaaataaga
     2641 acaggataaa tcgttcagga cagtcaaatc gatttctaaa aatgttttag aagtagaggt
     2701 gtactattct agtttcaatc tactatattt tgagcagcct aaagttagct ttctagtttg
     2761 ttctttgatt ttcattgtgt atttaaacac aaaaacaccc tgaaacatca gggtgccatt
     2821 cttacatcaa atacaaaatt gcaagggtca ggagacttgc tagaagccca actccccaaa
     2881 agaagaagtc aaccttccac tcgctccaag gatttccttt accagacaat cccccaagct
     2941 caaaatggtg atgtacaggc gtcatacgga aaatacgttt accacctgtc agtttgaaat
     3001 aactgacttg catcataaca gaagttgttt caaaaacata tacaattccg ataatcaaga
     3061 gagtccattc ttggtggaga gccatagaga tagctgccag catcccacct agggccaaac
     3121 ttcccacatc acccataaag accttagcag gcttatggtt aaagatgaaa aaactgagca
     3181 aaccaccaat catggcaaga atcactagaa gaatatccat ctgaccttgc acataggcaa
     3241 taactccata ggcagacaaa ctaatcacaa cggaaatact agctaaaccg tcaacaccgt
     3301 ctgtcaagtt tactgcgttt gaaaaaccga ctagccagaa aagagcgaag acaatataga
     3361 aaatccctag atgcacttga taaccaaaga cagaaagcat atcgccaccg cgctcataga
     3421 aaagatagaa gataactcca cctagaagct gaagagctaa tttttgctta ggattaagcc
     3481 cctcattgat tttacgaaag accttgagaa agtcatctaa aaatccgacc aagccataca
     3541 agaccaagat gaacaaaatc attcccatat tattgctgaa ttggctacta aatagggcga
     3601 aaaagaaagc aaccaaaaca gaagtaatca agaaaaccaa acctcccatt gtaggagtcc
     3661 cagcttttgc ctgatgctgt ttgacatcct catgcatctg ctggcctgta atttgcgcct
     3721 ttctataaaa ttggataaag gccggaattc ctactaaagt tagtaaaaat gtcacaattc
     3781 cagcactgat ggaaataaac atattagtct cctaaagtta atgtaatttt tttaatgtcc
     3841 ttgatagctg tgttagcacg aacatcttgc ttctgcacag tagagcccga accttgaaat
     3901 tcaagttcta tattgagcca cttagcaagg gtctcagcag tctcctttgt ccaaccatac
     3961 atatctggaa cttcctctac tttatcagat aagataagga cttgctgatt cggggcaaga
     4021 ttcttccctt cttcagcaga actgttttta atcttcgttc ctgttcccac aacgatgggt
     4081 tgtacaagat tgcgacgcaa ttcttctgct aaatcaccag gtgaaatatc cttgacacta
     4141 ggcataggat aaggactttg ttgacttact tgctccaaag ctttagctgt tgtttgaaga
     4201 ttgagagagt ctttcatagc tgaagcccgc tccaagatag gattggcaaa ttctcccaac
     4261 tgaatacctg aataatgttc aggttgttgg accgtcacat acaagataaa atcaggattt
     4321 tcagccggac tcatcgatac agccgagaaa atatagtcgg ttaacccgac tagataacca
     4381 ccatttttct cgtcagcaat ctgagccgta ccagacttga gggctacatt ttgcccagga
     4441 acagttacag ttggcttgcc tgtgctgtgg ttatacatgg ttccataaac cggatccgtc
     4501 cctaccaaaa ccatgttagt ccgagttaga ctagctgcat ctttagaaac aggatttccc
     4561 acaatttctt tttgagattt ccgagcagtt tgatcatttg gatcataaac ggcactaata
     4621 aatttaggct ccagcatgac accgtcatta gcaatagctg taaaggcacg aatcatttgc
     4681 gtctgggtca ctgaaatccc ttgtccaaat gagctttgcg caatgttgac aatattatcc
     4741 gcaggaagct gaccagcata ctcatccgtc aaaccgaaac gggtcggaac tccaaactta
     4801 aaacgattaa gataatcaag ccaggtagca tctcccatct tttgctcaag gagggtcatc
     4861 ccaacgttac ttgagtgtgc aaaaccttga gaaaaagtca tcattctgcc accagtcaat
     4921 ccttcattaa cgtcccaatc tcgaatcgtg gcatctgcaa tttttaactc actactatta
     4981 aagacttctc ctcctggaaa ggtattatta tcaatagcag cagccaacat catcactttc
     5041 atagtggaac ctggctcata gttactttgg taaaggatat cacgccaaac aaagtcctct
     5101 gtaatgcctt cttttgtatc tgcatcaaag gtcggtcgtt gcgttgttgc cagaatttcc
     5161 cctgttttag cactgaccaa agtcgctgtc atgtactttc cttttacctt ctcttgaaaa
     5221 gaatccatct gggtttccat aaaggactgg agggggctgg aaatggttgt ataaacatcc
     5281 ttaccgtcca tcgttcgttg ggaaacttgt tctgttccgg gtacaatatt acccagacga
     5341 tccttttcat aggtaataat gccgtctgtc cctgcaagaa tactgttcaa ggaactctcc
     5401 attccagagg ttcccagcaa gctcttgctt ccatcttcat tttcatggag ctgagctagg
     5461 ccgataaaac tagaagcaaa ttgtccgttt gggtaactac gattgggact ggttgtaaaa
     5521 tcaatcccct tgacctctgc agcttccaat tcttttttga tagacatcat attggcatag
     5581 gtaatcccat ttccctttgc tccaaaggaa acttgcttga gattaggttg cgagagttgc
     5641 tctcttacat aggattcttc catgtccaga tacttatgaa agacctctgc aaccttgtta
     5701 aattgtgttt tttctacgta aagaatctta cccgttgctg acttatagtt ctcatcaatg
     5761 accgcataga cattatagga ggttgcatcc tcagcaatcg ggactccatt tcggtcataa
     5821 atagtcccac gtttggcagg aactgtacgg gtggtttgat gaaccttctt agcttccttc
     5881 gctaaatctg ttccaaagcg agtgcctgtc ccaataatga ccgcaaaatt gactaaaaaa
     5941 atggcaaaaa caaagacaga taataaactc agactttttc caactctgcg tctgttttca
     6001 gccggcgatt tccgattttt ggtcgcataa cggattactc tttttgtcca cttcatatct
     6061 tactccgcta ttctaatatt ttcattgttt aattgcaaat cgtgtgaatt ggcaatttct
     6121 ttcaaacgtt ctgcacgtaa tagttcattg acctcttgct tggcatcgtc caattcggtc
     6181 ttcttttcct ctatctgcgc attgattttt gtcaaatcat tctgcacttg caagagcttg
     6241 gtctgcataa aaataatact aatggctaca ataagagtgg ttacagcaat ggaaaagtaa
     6301 aaagcttttt ccacacgcga aaaccgttta agttgcatct gtagtatttg acctgttttt
     6361 tccatttttt ctgccatctt tttccctctt acttgtgaat ttttctggcc acgcgcaact
     6421 tggctgagtg cgagcggtta ttggcttcta actcttccgc acttggcaag attggcttac
     6481 gggacaccaa ttccatcttg ggcttgagat catctgggat gaaaggcaag ccttttggaa
     6541 cttcaactgt tgaagcttcc ttgaacaatt gcttggtcaa gcggtcttct aaggaatgaa
     6601 aggtaatcac tgaaattcta ccatccagag ccaacatatc catagcctgc tggatggact
     6661 catctgccgc tcccagttca tcattgactt caattcgaat agcctggaaa atctgcttag
     6721 caggatgacc cttcttcttg agttccttgg caggtttgac caacttgata atctctgcta
     6781 actcagtcgt tgtctcaatc ggcttcactt cacgcgcttg ctcaatctta cgcgcaatct
     6841 gtttagagaa tttatcctca ccgtatttga agaaaatacg aaccaaatca tgatagtcat
     6901 agtgattaac cacttcatag gctgtcagac tagcatcctg attcatccgc atgtccagtg
     6961 gcgcatcctt tttataagaa aaaccacgct cacgctggtc caattgagga ctagacactc
     7021 ccaagtcata acaaattcca tcaatttcct gaacaccagc ttcgcgcaaa cgtgcctgta
     7081 aatgacggaa gttatccttg ataaaggtca ccattccctt ctcaatgtaa ggtgccaagc
     7141 gtttttgcgc attgtcaatg gcattctgat cctggtcaaa ggcatagaga tggccttttt
     7201 cacttaattt acttaataaa tactcgctat ggcctgctcc acccaaagtc gcatcaacgt
     7261 agataccgtc aggttttacg tcaagcatat caatcgtttc gtggagtaag accgttacat
     7321 gatgaaattc ttttgtcata tcttatctat tttaccacaa atccgaccag cttgcacttg
     7381 tcagacaaat aggacaagga gactactatt tcttcaaaaa atatgtcaaa tatacttgac
     7441 actttatgtt taaaagacta taatatagtc aaatatatac gacataaatc agaaaggaga
     7501 ccagatgaat cgtgtgaaag aatttcgcaa ggaattgggt atttcccagc tcgaactcgc
     7561 caaggatatc ggtgtctcga gacagactat caatatgatt gaaaacgaca agtacaatcc
     7621 aaccttggaa ctctgtctca atctcgcccg cagcctccaa actgacctca acagtctctt
     7681 ttgggaggaa gatttttaaa aaaggagcaa actcatgaaa aaagaaacct tcactgaaaa
     7741 actgatcaaa cgcacatacg gtatttctgg tccccttgac gaatacaaac ggcgtgaggc
     7801 cgatagtatt gggaaccaag tctttatcgt cctcttttat ctgatgattt tcggaaatct
     7861 tattccactc cttctagcct ataaataccc tcaagaagtg gctctaatct atcctcctct
     7921 gattttagtg attgccctca tcgctgctgg ctatgtcacc taccaaatga aaaaaacagg
     7981 catcacagtc attgaaccag atatgctgaa tgagaaagaa agcaagcaac tacactaccc
     8041 aggtctgaaa gcaggtttgt tctttggtct atggatgttt tttataactc ctcttctcag
     8101 tatactcata gatgaaggtc aggactattt tcattctctt ctcactataa gaaatggtgt
     8161 atcaagtatt ctcggttcta ttttcttcgg agcgagcata cagttcctca tctcccgtcg
     8221 cattgcaaaa actaagaaaa atcaagatga ggattaggag gaaactcatg aaaaaagaaa
     8281 agaaacagtt acgttatcct ggtctgaaag caggttcgat ttatggaaca gtgatatttt
     8341 ttataattcc actcattgat accctaacaa gtgaaaatcc aaattttatc agttctcttc
     8401 taaatacaaa acatattttt aaaactatac tgggagcttt ctttttcgga gtgatgatac
     8461 atattgtcga ctcacttcgt attgcaagag ctaaaaaaga ccaggattag gaggtgcctt
     8521 atgaaatcac tagctagact actgaacatt catgttttta tcagtatttt ccttttcttc
     8581 gcccttattt caggagctgt ttctcataca gttttactac tcctactcct ctttcttcct
     8641 gcgctcaata aaggacttga gaaaatacaa tcaaaacgga tacctgtcct caacgcagcc
     8701 ctcttctttc tcctcatatc ctttccacaa cttttaacca accctgtcca atggaaattt
     8761 tcaatattcc tagtcgtaac catcatttca agtttggcct acttctataa cttttatcaa
     8821 gtagttaaag aagtagatca aaaacagttg atttaggagc ttgctcccat aatttctcat
     8881 ttcataagca aataatccca cctagcttgt tctaggtggg attattttat ttcttaacag
     8941 agattgcaag tcattttcct tcattttaga aagtcgactc tttccaattc acactacaat
     9001 ccaagacttg ttgcctttct tcttgattac ggccttcaat ctgatcaatc aaaatctttg
     9061 tagcctgttg tccttcctca aaggagggct gaaccagcgt cgaaacactt ggagaagaaa
     9121 agcaagtcca ctccgtattg tcaaaaccaa tcaacccaac ttgtggcaag ttataattca
     9181 actctttgat aacggtaaag actagaggta gggcccaaca gttagggata aataccagag
     9241 ttttttcatc gggatcgatt tctttttgta aaaattcctt aatttgttcc aaattcgtat
     9301 gcttatcttc aatggttaga ctggcgtgac gcatattagc atctgttaaa gcatccacaa
     9361 aaccacttgc ccgctcaatc cgagtactca aacgactcgt atccgctgta atcaagagaa
     9421 aatgctcata acctttttcg atacaggact gggtcatgtc ataaacggca tcatagttat
     9481 tggttttaac ccagctagtc cggtgttcat agagctgact atcaaaaaag accattttct
     9541 tctttttctc atcgatgata cgagaatatt ttcggaaatt agaggtcggc tgaataataa
     9601 agccgtctac tcccaagaga agcatgcttt caatataccg gtcctcactc tcttggctgt
     9661 aattactatt tcctatcatt acctggtagc cattctggct ggcgatatcc tcaattccct
     9721 taacaatttg gtttgagaaa ctgttggtaa tatcaccgat caaaacaccg attaattttg
     9781 ttcgtttgga gtttaagcta cgcgcaacaa tgctcggttt gtaatttgtt tcatgaataa
     9841 ctttttcaat cttttcacgt gtctcttggg acattttttc atatttcccg tttaggtaaa
     9901 atgacacggt tgttttcgag gtctgagcca tttccgcaat gtcttttatg gtcagtttct
     9961 tctccaatct aaaacacctc ctactaatac ttattataa
//
LOCUS       DAVBCA010000069         9987 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.069, whole genome shotgun sequence.
ACCESSION   DAVBCA010000069 DAVBCA010000000
VERSION     DAVBCA010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9987)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9987)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9987
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.069"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..77
                     /locus_tag="VQU19_001831"
     CDS             <1..77
                     /locus_tag="VQU19_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET2481038.1"
                     /translation="MPQSPWVERIVQVLDLDYEDLFRR"
     gene            80..667
                     /locus_tag="VQU19_001832"
     CDS             80..667
                     /locus_tag="VQU19_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2481039.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQILYGSSLIS
                     FLWMYGQRKQAHKVNMKSRMKWLGVEFVSLLIISLCFSLIHAQGSTNQANLIGLQHQI
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHTGTILAWCLYV
                     SLGMFLGMVRYKSDLWGSMGLHLVWNLLVYSLLLF"
     gene            869..1006
                     /locus_tag="VQU19_001833"
     CDS             869..1006
                     /locus_tag="VQU19_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HET2481040.1"
                     /translation="MAEEVLNLQLVSVQVDETDEVDGMRFSTFSTNRCGNWSAFSWEN
                     C"
     gene            1185..3794
                     /locus_tag="VQU19_001834"
     CDS             1185..3794
                     /locus_tag="VQU19_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000386153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase"
                     /protein_id="HET2481041.1"
                     /translation="MDYNFNLEHPFFFTNNDYSTDTSIKYQVSLPFNWHEVMNNDEWV
                     YQYPIGKFVERQGWKIHISSEYNSSHELLQDVAKICHEMRIPFKHLSTEDKFIMRNGK
                     LVSRGFSGKFITCYPNQNELESVLQRLESALKQYNGPYILSDKRWDEAPIYLRYGVFR
                     PSRDDEKKVAIDELIVGDEVVKDERLPVFKIPKGIVPPDFLNKWLDKKDKKQGDFPFI
                     IDNAIRFSNSGGIYNARLKEDGKKIILKEARPYTGLGFDGTYSSEKLASECKALKILN
                     EWSETPKIYWHGKIWEHTFLGIEHMKGVPLNRWVTNNFPLYEVVDKTKDYLLRVSKIV
                     EKLIDLTNKFHSENVYHQDLHLGNILVKDEDEISIIDWEQAVFSNDEKVVHKVAAPGF
                     RAWRETLPSEIDWYGIRQIAHYLYMPLVTTSDLTYNYVSQTRIEGKKLFESLGYTREH
                     IDYVESLLSYLDSKCPQIENISRKKVLKPMHEIRTIESEQDIQDFIIKLLRGFTLTYG
                     QWRKEFQSRFFPVHYYGLNFNQGIAFSDLAILWSYQQLAKKVKNFKFDDYYEIRTQVI
                     NEAVNNFKKSSLSGLFDGKIGTIWLIYEFGEIDRAVELFTTHFIEIFENSQNKNLYSG
                     QAGILLVGLYFLSKGEIDNKLGEEILIRLREYTLNYIENPETFCKVGASDVQSNDPYE
                     NFGGLLYGHAGVAWLFGEAYKLTGESIYKNGLELAVDKELVAYKVDSNNSLQYSQGHR
                     LLPYLATGSAGLLLLINRNKEILSSKYLKYLTSLERATDVVFCVLPGLFNGFCGLEVA
                     NNIYSDIDDNFSGQKKLIEQLYRYLCVIEEGFVIAGDNGLKITTDIASGFAGVAIGLV
                     SIMDNKLTILPQI"
     gene            3827..5767
                     /locus_tag="VQU19_001835"
     CDS             3827..5767
                     /locus_tag="VQU19_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HET2481042.1"
                     /translation="MNQSNEIFLNTIQEKTHYKRSISSSFQELKKWNSLIFRRGRYWY
                     QFDNWSIPNTGVIKEWYVEDNDWIPKVSSSSLDNSNSLKIVFDVEKYTLPDDSILQDV
                     RISSDESYIVLVVSSLRSTNLIGIKKYTMEELFIIEDISVESSFYLGKFGVMYTRSKE
                     YGRPSKLFYKSFDSFTEEELFEENECSFRLKIVHIDSNNCFVKSVDFQKGRIFLYSFD
                     RTGFVRHSYTETVAPTPRDIALFSTEKAQYFLGLSSTEEKKDQLILRETSSGDRVSIT
                     IPYQDRARRVHCIGRYILLDCSNAANSVFYLATFKNNSLRELSVNKITFDEKTTLYEN
                     SFSDRVLLFLERRTFYEKILSFDLIENTLKTEFERPIIKSNNTKYFSKVIWTKKDSYD
                     VSIPISLFWKSEDTDELPRRKKCILSVYGAYGKNDNSDLDEIMLSIIDAGFIYAIVHV
                     RGGGYLGGEWYRSGKALNKWNSIRDFIEGVNYLRENDVIDSKRLGLITSSAGGIIAGA
                     VLNEEKNLLQSILLFSPFINPYDTLQNPNDPLSKTEIAEWGDIRDPEVKAYIKSYSPM
                     QNIEKARDSNTVIVNILGEKDPYINNNEVIEWSKKLNSIGVKSLLYLNKAAGHGGFTP
                     SDVLLMIDTLNYFFEEVGRNNL"
     gene            5764..7371
                     /locus_tag="VQU19_001836"
     CDS             5764..7371
                     /locus_tag="VQU19_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2481043.1"
                     /translation="MNYLKFIKKTKLILMGILIFLSSFNGVLLSGIIVYAGSLNQTSS
                     FSDVLRFGAISILGWSAIYISNYYLEVTEASITKDINVKIKQGYFREQYLSSEMVKDY
                     SSIISVLSNDLRLIEENYFRQIFEIISSILLFIVSLSFMLYLNFLVSIIFIVLSALPI
                     IVPVFMKKMLSNSANEYSNSNAEYTHIIKEIFNGFKTLKSYSVTKEIISLSDKKLDKL
                     EDSTFNLKRSEVLSKLVAVLISGFCFLVPLVVGCYFVIYHKSLSFSELIGIFLANDKV
                     LGPIQSIAYSLNKINTTKDLRKPFLKYLSGEKNFIDAEHDNNGLYTSSIDEIHMKDVV
                     YSITPENKLSIDFSFKSPFRVLLTGTSGSGKTTILNLINGSLKPQKGYVNLLSHGKKS
                     SDSIPTVDQTPYIFDTTIRENVTLFQNEYFSDDQIIEVLKKVNLYEELEKIDILNYQC
                     GENGSNLSGGQKQKIALARALIRNNKVYLFDEISANLDNDNSNSIHDILFNLGISFIE
                     VSHHYDLNDKRYTDIYKLENGTLFKIK"
     gene            7386..8126
                     /locus_tag="VQU19_001837"
     CDS             7386..8126
                     /locus_tag="VQU19_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2481044.1"
                     /translation="MDKDYILKVKGLYHQFLLGNNKTLQVLKNVSLSASRGEFISILG
                     ISGSGKSTLLKCISSLLEPTSGEVILNGINPYKIRNAKLSSIRRNEVSFIFQAYNLIP
                     SLPVIENIALPLRLSQKKLTIKNVENLLKRMKFNAGLNDFVGTLSGGEQQKVAIARAV
                     IADSDIIFADEPTGALDSVSREVIFELLRELVGAGKCVIMVTHDIELASKTDRALILK
                     DGKIFKELHRPSGEELYKILEVQSTTEE"
     gene            8129..9448
                     /locus_tag="VQU19_001838"
     CDS             8129..9448
                     /locus_tag="VQU19_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2481045.1"
                     /translation="MLRLVYYQFLHNKKQWLGVSPVIFVSSLVMGLAVNGVINVENNS
                     QVFVGLPDPKPIFMFPIVFGGVTLFFVLSNIINMLVEIFRDDYELLEVLGASLLQLSF
                     LVGGQIFIISSIISFIAYLCSIFVTSNYYYFLQYFFGENILPDIQFQTSAVGCIITVV
                     LISFLAFLSGCFYTFKKIRNRKSSKIRHVLSIVKRILLLAGFSVIWLLSLQQIFQDST
                     ILAKAQIIFNIVILDIVIIYQLSPFIQSCFIKLLSIIIFRNNFMFIASKWNLLYRKPY
                     IKSISAAITGAILLISSFQMISQNILSQFQDDSDLELKVAFIVYVGAPILIVLANIIS
                     IAFLSSHQERIEIQQFEILGTSNYQMVKIKVGEAIFLTFVTSLIAFLLNIKIMALIYY
                     SLEDVLIDDMNLLGLILPNFIVSIILFILIFITKSSYFIFKNAKIIS"
     gene            9582..9719
                     /locus_tag="VQU19_001839"
     CDS             9582..9719
                     /locus_tag="VQU19_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HET2481046.1"
                     /translation="MAEEVLNLQLVSVQVDETDEVDGMRFSTFSTNRCGNWSAFSWEN
                     C"
BASE COUNT         3389 a         1244 c         1910 g         3444 t
ORIGIN      
        1 gaatgcctca aagtccatgg gtagaaagga ttgtgcaggt attagattta gattatgaag
       61 atttatttcg gaggtaacta tgaaaagaat aattccagtt tatatattcc aacaagtaaa
      121 tgtcctattg gtatctctat acttattgaa atttctttgt atcggtgagt taactatact
      181 acagattctc tatggttcgt cactcatttc ttttttatgg atgtatggcc aacgcaaaca
      241 agcgcataag gtcaatatga aatctaggat gaaatggctt ggtgttgaat ttgttagcct
      301 actgattata agtctatgtt ttagtctgat tcatgctcaa ggaagcacga atcaagcaaa
      361 cttaattggc cttcaacatc aaattccttg gttttcattt ttattgttct taatcaatgc
      421 gagtatggtt gaagaatttc tgtatcgaga aattttatgg aatttggtca gaaaattaga
      481 tatcagagtt gctttgacaa gtgttttatt tgccttagca catcatacag gaaccattct
      541 agcttggtgt ttgtatgttt cacttgggat gtttttaggt atggtgcgct ataaatctga
      601 cttatggggc agtatgggac tacatttggt gtggaaccta ctagtttata gtttgctgct
      661 tttttaaaat aggtgacctg atttttaggt aacttctaaa actaacttcc agttttggga
      721 gagagatgga agttactttg aaaagttacg gaaacattat tttctatgtg acaacattgt
      781 ataattgctt gcattttact ggtggagaga gtataatgag ggtggataaa gtacttaatc
      841 ccaaaaattt aaataggagg agctagctat ggcagaagaa gtattaaatc ttcaattagt
      901 atctgttcaa gttgacgaaa cagatgaagt tgatggaatg cgatttagta cattcagtac
      961 aaatcgttgc ggtaactgga gtgcttttag ttgggaaaat tgttaattca tttaaattgt
     1021 aaactttaga gattctctgg agttatggat gtcgttccaa tatgtgcacg ttggaatgtt
     1081 agtgcttata tggggagaat ccaaaggatt ctcccttttt atttaaataa gtctgtctag
     1141 ctatagatat attaagtttg ataaaatttc ttggagattt tgttatggat tataatttca
     1201 atttggagca tcctttcttt ttcactaata atgattatag tacagatact agcataaagt
     1261 accaagtaag tctgcctttt aattggcacg aagtaatgaa taatgatgag tgggtttatc
     1321 aataccctat tggaaaattt gttgaaagac aagggtggaa aatacacatt agttcagagt
     1381 ataacagttc acatgaattg ttacaagatg tagcaaaaat ttgccatgaa atgcgaattc
     1441 catttaaaca tcttagtaca gaagacaaat ttatcatgcg aaacgggaaa ttggttagtc
     1501 gaggattttc tggtaaattt attacatgtt atccaaatca aaatgaatta gagtcggttt
     1561 tgcaaaggtt agaaagtgcc ttaaagcaat ataatgggcc atatatttta agcgataaac
     1621 gttgggatga agcaccaata tatctgaggt atggtgtgtt taggccgtca agggatgatg
     1681 aaaagaaggt tgctattgat gaattaattg ttggcgatga agttgttaaa gatgaacgtt
     1741 taccagtatt taaaattcca aaaggtatag tgccccctga ctttttgaat aaatggcttg
     1801 acaagaaaga taaaaaacag ggagactttc cctttattat agataatgca attagatttt
     1861 caaacagtgg tgggatatat aatgctaggc taaaagaaga tgggaaaaaa ataattttaa
     1921 aagaggctag accgtataca ggtctaggat ttgatggtac ttattcttca gagaaattag
     1981 cttcggagtg caaagcacta aaaattctaa atgaatggag tgagacgcct aaaatatact
     2041 ggcacggtaa gatctgggag cacaccttct taggaattga acatatgaag ggcgttccac
     2101 taaatagatg ggttaccaat aattttcctt tatatgaagt tgttgataag accaaagatt
     2161 atctattgag agtttcaaag atagtagaaa aactcatcga tttaacgaat aagtttcatt
     2221 ctgaaaatgt atatcatcaa gatttacatt taggaaatat cttggttaag gatgaagatg
     2281 agattagtat aatagactgg gaacaggctg tcttttcaaa tgatgaaaaa gttgtacata
     2341 aagttgcagc ccctggtttt agagcatggc gagaaacact tcccagtgag atagattggt
     2401 atggtattag acaaatagct cattatttat acatgccact agtaactaca tcggatttga
     2461 catacaacta tgtaagtcaa accaggatag aaggaaaaaa actatttgag tctttgggtt
     2521 atacaagaga acatatagat tatgtagaaa gtttattgtc atatctagat tctaaatgtc
     2581 cacagattga gaatatttcc aggaaaaaag ttttaaaacc catgcatgag attagaacta
     2641 tcgagagtga gcaagatata caagatttta ttataaaatt attgagaggg tttacgctaa
     2701 cttatggaca gtggcgtaaa gaatttcaat caagattctt cccagttcat tattatggtc
     2761 tgaattttaa tcaaggaatt gcgttttcag atttagctat cctttggagt tatcaacaac
     2821 tagctaagaa agtaaaaaat ttcaagtttg atgactatta tgagattcga acacaggtta
     2881 ttaatgaggc agtaaataat tttaagaaat cgtccctttc tggtcttttt gatggtaaaa
     2941 ttggtacaat ctggctcatt tatgaatttg gggagataga tcgggcagtt gaacttttta
     3001 caactcattt tatagagata tttgagaatt cacaaaataa aaatttatat agtgggcagg
     3061 ctggaatttt actggttgga ctgtattttc ttagtaaagg ggaaattgat aataaactag
     3121 gagaagaaat actaattagg cttagagaat atactttaaa ttatatagaa aatccagaaa
     3181 ctttttgtaa agttggcgct agtgatgttc agagtaatga tccttatgag aattttggtg
     3241 gattactata tggtcacgca ggggtagctt ggctcttcgg tgaagcttat aaattaactg
     3301 gtgaaagtat ctataaaaat ggtctagaat tggctgtaga taaagaatta gttgcttata
     3361 aagtagatag taataattca ttgcagtaca gccaaggtca tagattacta ccatatctag
     3421 caactggaag tgctggcctg cttttactta ttaatagaaa taaagaaatc ttgtcaagca
     3481 aatacttaaa atatttaact tctttagaga gggcaactga tgtagttttt tgtgtattac
     3541 caggtttatt taacggattt tgtggtcttg aagttgctaa taatatatat agtgatatcg
     3601 atgataactt ttcaggacaa aagaaattaa ttgaacaact ttatagatat ttgtgtgtaa
     3661 ttgaagaagg atttgttatt gcgggagata atggtttaaa gataacaaca gatattgctt
     3721 cgggatttgc gggtgttgca attggattgg tatcaataat ggataataaa ttgacgattc
     3781 ttcctcaaat ataatattta gataccatta ttaaggggtc atacttgtga atcagagtaa
     3841 tgaaatattt ttaaatacaa tacaggaaaa aacacactat aagaggtcta tctcttcatc
     3901 atttcaggaa ttaaaaaaat ggaattcttt gatatttagg agagggcgat attggtacca
     3961 atttgataat tggagtatac ccaatactgg tgtaataaag gaatggtatg tcgaagataa
     4021 tgactggatt cctaaggtta gttcttccag tttagacaat tcaaattcac ttaaaattgt
     4081 ctttgatgtg gaaaaatata ctttgccaga tgatagtatc ttacaggatg ttaggatttc
     4141 atctgatgag agttatatag ttttggttgt atcctcactg cgtagcacta atttaattgg
     4201 aataaaaaaa tatactatgg aagagttatt tatcattgaa gatatttcag tagaaagttc
     4261 gttctatttg ggtaaattcg gtgttatgta tactcgctcc aaagagtacg ggaggccaag
     4321 taagttattc tataaatctt ttgatagctt tacagaagag gaactgtttg aagaaaacga
     4381 atgctctttt cgattaaaaa tagtccacat tgatagcaat aattgttttg taaagtcagt
     4441 agactttcag aaaggcagga tttttctata cagtttcgac cggacgggtt ttgttagaca
     4501 ctcttacaca gaaacggtag ccccaacacc tagagatatc gctctattta gtacagaaaa
     4561 agcacagtac tttcttgggc tctcttcaac tgaagaaaag aaagatcaac taattctaag
     4621 ggaaacttct tcgggagaca gagtttctat tactatacca tatcaagata gggctagaag
     4681 agttcactgt ataggacgtt atatcctttt agactgttca aacgcagcga attccgtctt
     4741 ttatcttgct acatttaaaa ataatagttt gagggagttg agtgttaata agataacatt
     4801 tgatgaaaag acaacacttt atgaaaattc attttctgat cgtgttcttc tgtttttaga
     4861 gaggagaact ttttacgaaa aaatacttag ttttgattta atagaaaata cattaaaaac
     4921 tgaatttgaa agacccatca taaaatcgaa taatactaaa tatttttcta aggtgatttg
     4981 gactaaaaaa gacagttatg atgtaagcat accgatttct ttattttgga aaagtgaaga
     5041 tacggatgag ctcccaagaa gaaaaaaatg tattctaagt gtctatgggg cttatggtaa
     5101 gaatgataat tctgatttag atgaaattat gttatctata atagatgcag gttttattta
     5161 tgctatagtt catgtaagag gtggaggcta tttgggtggt gaatggtatc gctcaggaaa
     5221 ggcgttaaac aaatggaatt ctatcagaga ttttattgag ggagtaaatt atttaaggga
     5281 aaatgatgta attgacagta agcgattagg tttaataact tctagtgcag gtggaataat
     5341 tgctggtgcg gtgttgaacg aggaaaaaaa tttattgcaa agcattctct tattttcgcc
     5401 atttataaat ccttatgata cacttcagaa tccaaatgat cctctttcta agaccgaaat
     5461 agcagagtgg ggagatatta gagaccctga agtaaaggct tatataaagt catattcgcc
     5521 tatgcaaaat attgaaaagg cacgagactc aaatactgtt atagttaata ttttgggtga
     5581 gaaagaccca tatattaata ataacgaagt gatagagtgg tcaaagaaat taaattctat
     5641 tggagttaaa agtttgttgt atttaaacaa agcagctggt catggaggtt ttactccatc
     5701 agatgttctc ttaatgattg atactttaaa ttatttcttt gaagaagtgg gaaggaataa
     5761 cttatgaatt atttaaaatt tataaaaaag actaaactta tattaatggg gattttaata
     5821 tttctatctt cgtttaatgg tgtcttgctc tcaggaatta ttgtatatgc aggtagttta
     5881 aatcagactt cctcattttc tgacgttcta agatttggtg ctataagtat tctgggttgg
     5941 tcagcaatct atatatcaaa ttactattta gaagtaacgg aagcatcaat aacgaaagat
     6001 ataaatgtaa aaattaaaca aggatatttt agagaacagt atctttcttc tgaaatggtt
     6061 aaagattact catctattat ttcagttttg tcaaatgatt tgagattaat cgaagaaaac
     6121 tattttagac aaatttttga aataatttct tcaatattgt tgttcatcgt ctctctaagt
     6181 tttatgcttt atttaaactt cctagtttca ataatattta ttgtattatc agcattgccg
     6241 attatagtac ctgtctttat gaagaagatg ttgtctaatt cagctaatga gtactctaac
     6301 agcaatgcag agtatactca cataataaaa gaaattttta atggttttaa gacattaaaa
     6361 tcttattctg ttactaaaga aataattagt ttgtcggata aaaagttgga taaactagaa
     6421 gattctactt ttaatttgaa acgatcagag gttctttcaa aattggttgc agtactaatt
     6481 tcaggttttt gctttctagt tcccttggtt gtaggatgtt attttgtaat ttatcataaa
     6541 agcctttctt ttagtgaact gataggtatt ttcttagcaa acgataaagt tttagggccg
     6601 atacaatcaa ttgcctattc attaaataag ataaatacaa ccaaagattt aaggaaaccg
     6661 tttttaaaat acttaagtgg agagaagaat tttatagacg ctgaacatga taataacgga
     6721 ctgtatactt catcaataga tgagatacac atgaaagatg ttgtatattc tattacacca
     6781 gaaaataaat taagtattga cttctcattt aagtcaccat ttagggtatt attaacagga
     6841 acttctggta gtgggaaaac aacgatttta aatttaatta atggttcttt aaagccacaa
     6901 aaaggttatg taaatttgtt atcacatggg aaaaagagtt cagattcaat accaacagtt
     6961 gatcagacac catatatttt tgacactact attcgtgaga acgtaacttt atttcaaaat
     7021 gaatattttt cagatgatca gataattgag gtgttaaaaa aggtaaatct atatgaagaa
     7081 ttagaaaaga tagatatact aaattatcaa tgtggtgaaa atggtagtaa tttgtctgga
     7141 ggtcaaaaac aaaaaatagc tttagctaga gctctgatta gaaataataa agtgtactta
     7201 tttgacgaaa tatcagctaa tttagataat gataattcaa attccataca tgatattctg
     7261 ttcaatttag gtatttcatt tattgaagtt tcacatcatt atgacttaaa tgacaagaga
     7321 tacactgata tatataaatt ggaaaatgga acacttttca aaattaagtg attggaggca
     7381 agaatatgga taaagattat atattaaaag tgaaagggct gtatcatcaa tttttactag
     7441 gaaataataa aacgttgcaa gtgctgaaaa atgtttctct ttctgcttcg agaggagaat
     7501 ttataagtat tctaggaatt agtggttctg gaaagtcaac tttattaaaa tgtatttcta
     7561 gtttgcttga accaacaagt ggggaagtaa ttttaaatgg aatcaacccc tataaaatca
     7621 gaaatgcaaa attgtcaagt ataagacgta acgaagtatc ttttatattt caagcataca
     7681 atttaatacc ttccctgccg gtaatagaaa atatagcact tcctttgcga ttatcacaaa
     7741 aaaaattaac tattaaaaat gtagaaaact tactcaaaag aatgaagttt aatgctggct
     7801 taaacgattt tgttggaact ctgtctggtg gagaacaaca gaaggttgct atagctagag
     7861 cggttattgc tgatagtgat ataatatttg ctgatgagcc aactggggct ttagacagcg
     7921 tttctcgtga agtaattttt gaattattga gagagttagt aggggcgggt aagtgtgtaa
     7981 ttatggtaac gcacgatata gaattggcct cgaaaactga tcgtgcatta atattgaaag
     8041 atggaaaaat tttcaaagaa cttcatagac ctagcgggga agagttgtat aaaatcttag
     8101 aggtacaatc aactacggag gaatagagat gctcagatta gtttactatc aatttttaca
     8161 taataagaaa caatggttag gcgtttcacc agtaattttt gtttcgagtt tagttatggg
     8221 attggctgtt aatggggtaa ttaatgttga gaataattcg caagtatttg tcggacttcc
     8281 agatcctaaa ccaattttta tgtttccgat agtattcgga ggagtaacat tattctttgt
     8341 gctctctaac ataataaata tgttggttga aatttttaga gatgattacg aacttctgga
     8401 ggtgttggga gcaagtctcc ttcaactatc atttcttgtg gggggacaga tttttatcat
     8461 ttcctcgatt attagtttta ttgcatatct atgctctata tttgttacgt caaattatta
     8521 ttatttttta caatactttt tcggggaaaa tatattacct gatatccaat ttcaaacgag
     8581 tgctgttgga tgtatcatta cagtagtgtt gatttcattt ttagcctttc taagtggttg
     8641 cttttatacg ttcaagaaga ttagaaatag gaagagttct aaaataaggc atgttctttc
     8701 aatagtaaaa agaatactgc tattggctgg ttttagtgtt atctggttgc tttctttgca
     8761 acaaattttc caagatagca caattttagc gaaggcccag ataatattca atattgtaat
     8821 cttagatatt gtgattattt atcaattatc tccttttata cagtcatgtt ttatcaaact
     8881 actttctata attatattta gaaataattt tatgttcatt gcttcgaagt ggaatttact
     8941 atatcgtaag ccttatataa aatctatcag tgctgcaatt acaggagcta tattactaat
     9001 ttctagtttt caaatgattt ctcagaatat actatctcaa tttcaagatg acagtgattt
     9061 agagctaaaa gtggcattta ttgtctatgt aggagcacca attttgatag tacttgcaaa
     9121 tattatttca attgcatttt tgtcatcgca tcaagaaagg attgagattc agcaatttga
     9181 aattttagga acttctaatt accagatggt taagattaaa gttggtgagg ctatattttt
     9241 gacatttgtt acttcattaa ttgcattttt acttaacatt aaaattatgg ctttaatata
     9301 ctactcttta gaggatgttt taatagatga tatgaatctt ttggggttaa tacttccaaa
     9361 ttttatagtg tctattattt tatttatttt aatatttatt actaaaagtt cctattttat
     9421 ctttaagaat gcaaaaatta tttcttaaaa atttgtaagt tttcgctata taaaatagtt
     9481 aaatctattt tgtatcattg cttgcatttt actggtggag agaatataat gagggtggat
     9541 aaagtactta atcccaaaaa tttaaatagg aggagctagc tatggcagaa gaagtattaa
     9601 atcttcaatt agtatctgtt caagttgacg aaacagatga agttgatgga atgcgattta
     9661 gtacattcag tacaaaccgt tgcggtaact ggagtgcttt tagttgggaa aattgttaat
     9721 tcatttaaat tgtaaacttt agggattctc tgaagttatg gatgtcgttc caatatgtgt
     9781 acgttggaat gttagtgctt atatgggggg aacagaatcc tctcttgatt gaagacaagt
     9841 tagccattag gctggtttgt ctctttgtca actgtagtgg gttgatataa tagtattagt
     9901 gagtgggata aaagtttcat ttagtttatt cagtacaaat ttaacgggtc aagatttatt
     9961 gaactgcacc ccaatagtta gacagaa
//
LOCUS       DAVBCA010000070         9647 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.070, whole genome shotgun sequence.
ACCESSION   DAVBCA010000070 DAVBCA010000000
VERSION     DAVBCA010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9647)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9647)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9647
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.070"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(302..1282)
                     /gene="dusB"
                     /locus_tag="VQU19_001840"
     CDS             complement(302..1282)
                     /gene="dusB"
                     /locus_tag="VQU19_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HET2481047.1"
                     /translation="MTNLNTPFMIGNIEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(1269..2141)
                     /gene="hslO"
                     /locus_tag="VQU19_001841"
     CDS             complement(1269..2141)
                     /gene="hslO"
                     /locus_tag="VQU19_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HET2481048.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQERHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGAGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            2306..3733
                     /locus_tag="VQU19_001842"
     CDS             2306..3733
                     /locus_tag="VQU19_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET2481049.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELTIHSEDENLRLSIGAATKGRDIRSLFLDSAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSAGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLAGIRQLLFT"
     gene            3892..5400
                     /gene="glpK"
                     /locus_tag="VQU19_001843"
     CDS             3892..5400
                     /gene="glpK"
                     /locus_tag="VQU19_001843"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HET2481050.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            5442..7268
                     /gene="glpO"
                     /locus_tag="VQU19_001844"
     CDS             5442..7268
                     /gene="glpO"
                     /locus_tag="VQU19_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HET2481051.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKDQVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKHLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELALSPVDFLLRRTNHMLFMRDSLD
                     SIVEPILDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            7338..8042
                     /locus_tag="VQU19_001845"
     CDS             7338..8042
                     /locus_tag="VQU19_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HET2481052.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTIGVALKGGLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            8339..8542
                     /locus_tag="VQU19_001846"
     CDS             8339..8542
                     /locus_tag="VQU19_001846"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2481053.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEDKKQELLNRLNK"
     gene            complement(8629..9216)
                     /locus_tag="VQU19_001847"
     CDS             complement(8629..9216)
                     /locus_tag="VQU19_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2481054.1"
                     /translation="MFVFADDSLSANSKVVSGEAQFENGSSVRFGDTQVNILSDEVLE
                     VVNPDGSVDTIERRADGVYINGAFYMAYQKNEIDLNISFRSYDPNVWNYVNTIHGNKQ
                     ANTFANFMTGAGISYMIGRIGTLLGGPWGAIIGGAYFGIQAYQSYLDSQSPYPYYITS
                     TYIHVAQKKWKFITEYYRNSNYTGYVKTVTTYVNF"
BASE COUNT         2791 a         1922 c         2181 g         2753 t
ORIGIN      
        1 tcaggtgccc ttgcagtcaa cacaactgta gatagctata gagtcaatgc caatggtgaa
       61 tgggtaaact aaacctaata taactagtta atactgactt cctgtaagaa ctctttaaag
      121 tattccctac aaataccata tcctttcagt agataatata cccttgtagg aagtttagat
      181 aaaaaaataa ctctgtaatc tctagccgga tttatagcgc tagagactac ggagtttttt
      241 tgatgaggaa agaatggcgg cattcaagag gctctttaag agagttacgg gttttaaact
      301 attaagcctt ctccaattgc aagagggctt caatctctgc cagggtgcta gcttgcgaaa
      361 tggctccacg gagtttggca gcgccagatg ttccacggag atagtgagga gcgaggccgc
      421 ggaattcacg aactgcgacg ttttctcctt tgaggttaat caatcgtttc aagtgttcgt
      481 aggcgatctt catcttgtct tcaaaggtca aatcaggtag gatttctcct gtttcaaagt
      541 aatggttgat ttggttgaag aggtaaggat ttcccatggc agctcggcca atcatgactg
      601 cgtcagcacc aacttcttcg atgcgttgct tggcttcttg gacagtacgg atatcaccgt
      661 tggcgatgaa tggaatcttg gttagagctt gggcaacctt gtaaagggtc tcaaggtctg
      721 cgtggccagt atacatttgt tcacgggtac ggccatgcat ggcgagggca gaaacacctg
      781 cagcctcagc agcgagggca ttttctactg caagagatgg gtccgcccat ccggtacgca
      841 ttttgacagt aagtgggata tcaaggacag actggacctt gttgatgata gagtagatct
      901 tgtcaggatc cttgagccac atagctccag cttcgttctt cacgattttg ttgacagggc
      961 agcccatgtt gatatcgacg atatcggtct tggtgttttc ttggatgaat tctgctgcgc
     1021 gtgctaggct gtcttcatcg ctaccaaaaa gttggataga gacagggttt tcgccctcat
     1081 cgatatgaag catgtgcagg gttttttcgt tgttgtattg gattcccttg tcagagacca
     1141 tttccattac aacgagtcca gctccgagct cttttgcgat ggtacgaaag gctgagttgg
     1201 tcacgccagc cataggcgct aaaacggtac gattgggaat ctcaatattg ccaatcataa
     1261 aaggtgtatt aagatttgtc acgaatgagt tcctccaggt ccttttcatc aaagttgtaa
     1321 gtagtttggc agaattgaca agtgatttct gccccgtggt cttcctcttt catttcctgt
     1381 aagtctgagc ttggaaggct ggcaagagcg ttcataaagc gttcatggct acagtcacat
     1441 tggaaacgga tttcttcttc agaaagacgc ttgtaggctt cgtccccgta gatagccttg
     1501 aggagggctt cgatatggtc gtcgctttcg agaagagtag agatagctgg catttcttgg
     1561 atgcgttttt caaagcgagc aatctcttct ttcttggctc ctggcaagac ttgaactagg
     1621 aaaccacctg caaccttgac cttgtcttcc tcgtccaaaa ggacattgag gccgaccgct
     1681 gaaggcgttt gttggctttc agtaaggtaa aaggcaaggt cttcaccgat ttctccagag
     1741 atgaggggag ttatagagtt gtaaggattt ccagcaccgt agtctgtgat aacgaggaat
     1801 tgaccatttc caacaaaagg tccgactagg acttcaccag tcgcagtctt tttgatgtca
     1861 acaccaggat tttgaacata gcctttgacg ttccccttgg tatcagcgac ggtgataata
     1921 gcacctagag agctagagcc caacacctta actgtaagtt tggtatttcc tttttcattg
     1981 gctgcgagaa tctggctagc gataagagtt cgaccaagcg ctacagttga gctagcttgg
     2041 gtttgatgtc tttcttgagc agtgcggacg gtttccgtgc tatcaaggac aaaagcacga
     2101 aaggctccgc tttctgatat agttttaata attttatcca tagctactat tttagcataa
     2161 aaatgcccaa agggggagcc gtgtgtttac tgattttcag gataatggac caggaaatca
     2221 gcatgaaaat aaaaagagaa acagattatt tcagcatttg taagatttat gctatgctta
     2281 aggtagaaaa tgaaaggggt aacaaatgta tttaggagat ttgatggaga aagccgagtg
     2341 tggtcaattt tcaatccttt cctttctatt acaagagtct cagacgaccg tcaaggctgt
     2401 aatggaagaa acaggatttt caaaagcaac cctaaccaaa tatgtcaccc tgctcaatga
     2461 caaggctttg gatagtggct tagaactgac tattcactca gaagatgaaa atctgcgtct
     2521 gtctatcggt gcagctacca aggggagaga tattcggagc ttgtttttgg atagtgctgt
     2581 taaataccag attttggttt atcttctcta ccaccaacag tttttagccc atcagctggc
     2641 tcaagaattg gtgattagcg aggctacgct tggtcgtcac ttggctggtt taaatcagat
     2701 tttgtcagaa tttgatttat ccatccaaaa tggacgctgg agaggtccag agcatcagat
     2761 tcgctatttc tatttctgtc ttttccgaaa ggtctggtcg agtcaggaat gggaaggtca
     2821 catgcagaaa ccagagagaa aacaggagat tgccaattta gaggaaatct gcggtgcaag
     2881 tttgtctgcg gggcagaaat tggacttggt tctctgggct cacatcagtc aacaacgtct
     2941 tcgggtcaat gcttgtcagt ttcaagtcat agaagagaaa atgcgagggt attttgacaa
     3001 tatcttttat cttcgtttgc tgagaaaggt tccgtccttt tttgctgggc aacatattcc
     3061 actaggagtt gaggatggtg agatgatgat attcttctct tttctcctat ctcatcgcat
     3121 tcttcctctt catactatgg agtatattct tggttttgga gggcagttgg cagatttact
     3181 gacgcaattg attcaagaaa tgaagaagga ggaactattg ggggattata cagaggacca
     3241 tgtcacctat gaactcagtc agctttgtgc tcaagtctat ctctataagg gctatatttt
     3301 acaggatcgc tacaagtacc agttagagaa tcgtcatcca tatttactga tggaacatga
     3361 ttttaaagag acagcagagg agatttttca tgctctacct gcttttcaac aggggacaga
     3421 tttagataag aagattctct gggaatggct ccagttaatc gaatatatgg ctgaaaacgg
     3481 tggccagcat atgcggattg gtctggattt gacatctggt tttcttgtct tttcaaggat
     3541 ggcagccatt ttgaaacggt atttggaata caatcgtttt attaccattg aagcttatga
     3601 ccctagtcgg cattatgatt tgctggttac caataacccg attcataaga aggaacagac
     3661 accagtctat tatttaaaaa acgacttgga tatggaagat ttggcaggga ttcgtcagtt
     3721 attattcact taaaaggctt ggttaatcta ggtctttttt gtgaaattca cacaatctcc
     3781 tcacattttt ttaaaaatta aaaaaagttg ataaacaaga aagcgcttta ttttgtatac
     3841 tagtaagtgt aaagaggaaa cacctcaaga tctttatcag gaggacagta catgtcacaa
     3901 gaaaaataca tcatggccat tgaccaggga actacaagtt ctcgtgccat cattttcaac
     3961 aaaaaagggg aaaaggttag ctcgagtcaa aaagagttta cccagatttt ccctcaggca
     4021 ggttgggttg agcacaatgc caatgaaatt tggaactctg ttcagtcagt tattgcgggt
     4081 gctttcatcg aaagtggtgt caagccaaat caaatcgagg caatcgggat taccaaccaa
     4141 cgtgaaacaa cggttgtctg ggataagaaa acaggacttc ctatctacaa tgctatcgtt
     4201 tggcagtcac gccagacagc acctttggct gagcaactaa aaagccaagg ttatgtggaa
     4261 aaattccatg aaaagactgg tttgattatt gatgcttact tctctgctac caaggttcgt
     4321 tggattttgg atcatgtaga aggtgctcaa gagcgagcag aaaaagggga attgctcttt
     4381 ggtactatcg atacttggtt ggtttggaaa ttgactgacg gtgcggctca cgtgactgac
     4441 tactcaaatg cagctcgtac catgctttat aacattaaag aactcaaatg ggatgatgag
     4501 attttggaaa tccttaacat tccgaaggct atacttccag aagttcgttc taactccgaa
     4561 atctacggca agacagctcc attccatttc tacggtggag aggtgccaat ctcaggtatg
     4621 gctggggacc aacaagcagc cctctttgga cagttggctt ttgagccagg tatggttaag
     4681 aatacttatg gaacaggctc tttcatcatc atgaatactg gggaagagat gcagttgtct
     4741 gaaaacaacc tcttgacaac cattggttac ggaatcaacg gtaaggttta ttatgccttg
     4801 gaaggttcta tcttcatcgc aggaagtgct attcagtggc ttcgtgacgg tcttcgcatg
     4861 gttgaaaatt caccagaatc tgaaaaatac gctcgtgatt ctcacaacaa cgatgaagtt
     4921 tatgtcgttc cagcctttac aggtctaggc gctccatact ggaaccaaaa tgctcgtggt
     4981 tccgtctttg gtttgactcg tggaacaagc aaagaagact ttatcaaggc gactttgcaa
     5041 tctattgctt atcaagtgcg tgatatcatc gacaccatgc aagtggatac tcagaccgcc
     5101 attcaagtac tgaaggtgga tggtggtgca gccatgaaca acttcctcat gcagttccag
     5161 gcggatattt taggcattga cattgcacgt gctaaaaacc tggaaacaac agctctagga
     5221 gcggccttcc tagcaggttt gtcagtaggg tactggaaag acttggacga gttgaaactc
     5281 ttgaacgaga caggagaact ctttgagcca tctatgaacg aatctcgcaa ggaacaactc
     5341 tacaagggct ggaagaaggc tgtgaaagca actcaagtct ttgcggaagt agacgactaa
     5401 tactggcaga ataaagcgat ttatttagaa agtgtgtaaa tatggaattt tcaaagaaaa
     5461 cacgtgaatt gtcaattaaa aaaatgcagg aacgcaccct ggacctcttg attatcggtg
     5521 gaggaatcac aggagctggt gtagccttgc aggcggcagc tagcggtctt gagactggtt
     5581 tgattgaaat gcaagacttt gcagaaggaa catctagtcg ttcaacaaaa ttggttcacg
     5641 gaggacttcg ttaccttaaa caattcgacg tagaagtggt ctcagatacg gtttctgaac
     5701 gtgcagtggt tcaacaaatc gctccacaca ttccaaaacc agacccaatg ctcttaccag
     5761 tttacgatga agatggagca acctttagcc tcttccgtct taaagtagcc atggacttgt
     5821 acgacctctt ggcaggtgtt agcaacacac caactgcgaa caaggttttg agcaaggatc
     5881 aagtcttgga acgccagcca aacttgaaga aggaaggctt ggtaggaggt ggagtgtatc
     5941 ttgacttccg taacaacgat gcgcgtctcg tgattgaaaa catcaaacgt gccaaccaag
     6001 acggtgccct cattgccaac cacgtgaagg cagaaggctt cctctttgac gaaagtggca
     6061 agattacagg tgttgtagct cgtgatctct tgacagacca agtatttgaa atcaaggccc
     6121 gtctggttat taatacaaca ggtccttgga gtgataaagt acgtaatttg tctaataagg
     6181 gaacgcaatt ctcacaaatg cgcccaacta agggagttca cttggtagtg gattcaagca
     6241 aaatcaaggt ttcacagcca gtttactttg acacaggttt gggtgacggt cgtatggtct
     6301 ttgttctccc acgtgaaaac aagacttact ttggtacaac tgatacagac tacacaggtg
     6361 atttggagca tccaaaagta actcaagaag atgtagatta tctacttggc attgtcaaca
     6421 accgctttcc agaatccaac atcaccattg atgatatcga aagcagctgg gcaggtcttc
     6481 gtccattgat tgcagggaac agtgcctctg actataatgg tggaaataac ggtaccatca
     6541 gtgatgaaag ctttgacaac ttgattgcga ctgttgaatc ttatctctcc aaagaaaaaa
     6601 cacgtgaaga tgttgagtct gctgtcagca agcttgaaag tagcacatct gagaaacatt
     6661 tggatccatc tgcagtttct cgtgggtcta gcttggaccg tgatgacaat ggtcttttga
     6721 ctcttgctgg cggtaaaatc acagactacc gtaagatggc tgaaggagct atggagcgcg
     6781 tggttgacat cctcaaagca gaatttgacc gtagctttaa attgatcaat tctaaaactt
     6841 accctgtttc aggtggagaa ttgaacccag caaatgtgga ttcagaaatc gaagcctttg
     6901 cgcaacttgg agtatcacgt ggtttggata gcaaggaagc tcactatctg gcaaatcttt
     6961 acggttcaaa tgcaccgaaa gtctttgcac ttgctcacag cttggaacaa gcgccaggac
     7021 tcagcttggc agatactttg tcccttcact atgcaatgcg caacgagttg gctcttagcc
     7081 cagttgactt ccttcttcgt cgtaccaacc atatgctctt tatgcgtgat agcttggata
     7141 gcatcgttga gccaattttg gatgaaatgg gacgattcta tgactggaca gaagaagaaa
     7201 aagcaactta ccgtgctgat gtcgaagcag ctctcgctaa caacgattta gcagaattaa
     7261 aaaattaaga aaaaataaaa gaggtggagg gcagcattcc ttgtcgcccg tcccttcttt
     7321 ttaatggaga cagaaagatg atgaatgaat tatttggaga atttctaggg actttaatcc
     7381 tgattcttct aggaaatggt gttgttgcag gtgtggttct tcctaaaacc aagagcaata
     7441 gctcaggttg gattgtgatt actatgggtt gggggattgc agttgcggtt gcagtctttg
     7501 tatctggcaa gctcagtcca gctcatttaa acccagctgt gaccatcggt gtggccttaa
     7561 aaggtggttt gccttgggct tccgttttgc cttatatctt agcccagttc gcaggggcca
     7621 tgctgggtca gattttggtt tggttgcaat tcaaacctca ctatgaggca gaagaaaatg
     7681 caggcaatat cctggcaacc ttcagtactg gaccagccat caaggatact gtatcaaact
     7741 tgattagcga aatccttgga acctttgttt tggtgttgac aatctttgct ttgggtcttt
     7801 acgattttca ggcaggtatc ggaacctttg cagtgggaac tttgattgtc ggtatcggtc
     7861 tatcactagg tgggacaaca ggttatgcct tgaacccagc tcgtgacctt ggacctcgta
     7921 tcatgcacag catcttgcca attccaaaca agggagacgg agactggtct tacgcttgga
     7981 ttcctgttgt aggccctgtt atcggagcag ccttggcagt gcttgtattc tcacttttct
     8041 agtttatact cttcgaaaat caaattcaaa ccacgtcagc gtcgccttac cgtactcaag
     8101 tacagcttac ggctagcttc ctagtttgct ctttgatttt cattgagtat tagaaaacaa
     8161 ttatgttgat agagcttggg caagagccca atttcagcaa aaaatgaagt aaatcttctc
     8221 ataataaaac gcatcatatc aagcacgaaa attccacgag gtcaactaca gtcagaaagc
     8281 tgaacaacaa gccaaaacgc ccaaaaaagg cggcaaaaag caagcacctg caagcaacgt
     8341 gccgaaatgg tcaaatcctg attatgtcaa cgaattagac ccaaaaatcg ttgatatgct
     8401 agtagaattt cacaagtcac aaggcacttt ggaaactccc gaggcgcaag cagaaatcgc
     8461 ccaaaaacgt gaagaaatcg agcaaaggag agctgagctt gaggataaaa aacaagagct
     8521 tttgaaccgc ttgaacaaat agagtttcgc aagtattatg cttacaaatt acttgagcaa
     8581 ttaactaaaa tataaaccct gcctttatat ctaggcaggg tttatatttt agaaattcac
     8641 gtaggttgtt acggttttta catacccagt atagtttgag tttctatagt attcagtgat
     8701 aaacttccat tttttttgag caacatggat ataagtactt gttatgtagt atggatatgg
     8761 gctttgtgaa tccaagtaag actgataagc ttgtatacca aaatatgctc caccaattat
     8821 tgcaccccat ggacccccca ataaagtacc tatcctacca atcatataac tgattccagc
     8881 accagtcatg aagttagcga atgtgttagc ttgtttattc ccatgtattg tgttgacgta
     8941 attccaaaca ttaggatcgt atgatctaaa agatatattt aggtcgattt cattcttttg
     9001 ataagccata taaaatgccc cattgatata gacgccgtca gcacgtcgtt caatagtgtc
     9061 tacacttcca tctggattga caacctcaag aacttcatcg cttaaaatat ttacttgcgt
     9121 atctccgaac cgcactgatg agccattctc aaactgagcc tcaccagata caactttaga
     9181 gtttgccgat aagctatcat cagcaaaaac aaacaagcga cggggaaatg ctagacatac
     9241 agaaaacaga cataactagc aaacacatgc atttaaacat cttagacata acggaaactc
     9301 ctttgtattt ttgatttttt tcaactttta ttatacaata aaaccaaata aaaagaaagc
     9361 ggtaacaata tgcttaatgc gaaaattttt tatatatttt tatgtttgat cgttatcgaa
     9421 actacaggct tgttgttgtt gaaaagaggt ctcgaaatgg gttatttaga cacagaagct
     9481 attatcctcg cagttttttc atttgctttt tacaacctat gttcattcgc ttgggtctgc
     9541 tctacaataa aaaacaataa aaaataaata gacgtatttt caaaaaaaaa aaaaaaaaat
     9601 gcatatttat cttagcaaaa cgacaattta aatcgtcgtt tttttgt
//
LOCUS       DAVBCA010000071         9471 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.071, whole genome shotgun sequence.
ACCESSION   DAVBCA010000071 DAVBCA010000000
VERSION     DAVBCA010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9471)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9471)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9471
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.071"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            150..686
                     /locus_tag="VQU19_001848"
     CDS             150..686
                     /locus_tag="VQU19_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HET2481055.1"
                     /translation="MKKAHVYAIPAIGAALIAALAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALAVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            737..823
                     /locus_tag="VQU19_001849"
                     /pseudo
     CDS             737..823
                     /locus_tag="VQU19_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(892..1107)
                     /locus_tag="VQU19_001850"
     CDS             complement(892..1107)
                     /locus_tag="VQU19_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HET2481056.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            1205..1525
                     /locus_tag="VQU19_001851"
     CDS             1205..1525
                     /locus_tag="VQU19_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2481057.1"
                     /translation="MRHKFQQVLNKIHDFLNGYDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFAKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            complement(1556..1894)
                     /locus_tag="VQU19_001852"
     CDS             complement(1556..1894)
                     /locus_tag="VQU19_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2481058.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(1906..2625)
                     /gene="trmD"
                     /locus_tag="VQU19_001853"
     CDS             complement(1906..2625)
                     /gene="trmD"
                     /locus_tag="VQU19_001853"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HET2481059.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            complement(2615..3133)
                     /gene="rimM"
                     /locus_tag="VQU19_001854"
     CDS             complement(2615..3133)
                     /gene="rimM"
                     /locus_tag="VQU19_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HET2481060.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKRYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            complement(3164..3952)
                     /locus_tag="VQU19_001855"
     CDS             complement(3164..3952)
                     /locus_tag="VQU19_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET2481061.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADAVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKRQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFEDVSIEAHIPVFVFCQP
                     YREKEYRESEYWTSNTKLILGGNHHYLQWSESEKIAAIIRELSE"
     gene            complement(4529..4768)
                     /locus_tag="VQU19_001856"
     CDS             complement(4529..4768)
                     /locus_tag="VQU19_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HET2481062.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            complement(4788..5060)
                     /gene="rpsP"
                     /locus_tag="VQU19_001857"
     CDS             complement(4788..5060)
                     /gene="rpsP"
                     /locus_tag="VQU19_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HET2481063.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            5230..5439
                     /locus_tag="VQU19_001858"
     CDS             5230..5439
                     /locus_tag="VQU19_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2481064.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERELDTWLLSPKPVPKRNMDL
                     LVDDSLAGDIILLWRIQFGTFTTET"
     gene            5918..6139
                     /locus_tag="VQU19_001859"
     CDS             5918..6139
                     /locus_tag="VQU19_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2481065.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEEVEDFQDDDEIPTII"
     gene            6222..7025
                     /locus_tag="VQU19_001860"
     CDS             6222..7025
                     /locus_tag="VQU19_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HET2481066.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQSSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(7081..8622)
                     /locus_tag="VQU19_001861"
     CDS             complement(7081..8622)
                     /locus_tag="VQU19_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET2481067.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMEMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DLPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(8624..9106)
                     /locus_tag="VQU19_001862"
     CDS             complement(8624..9106)
                     /locus_tag="VQU19_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HET2481068.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVYFCFTPQEQSTVGVGTPDIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNILNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            complement(9106..>9471)
                     /locus_tag="VQU19_001863"
     CDS             complement(9106..>9471)
                     /locus_tag="VQU19_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S rRNA methyltransferase"
                     /protein_id="HET2481069.1"
                     /translation="KLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALELAELLKNI
                     KKSSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGGNCVVRQEHGTDIDAACGQ
                     LLFNTMKRDRQKAVAAVNP"
BASE COUNT         2796 a         2028 c         1698 g         2949 t
ORIGIN      
        1 attttcgaat caacaaaaaa attatccaac ttgactagtc acgaaaatcg gctgttacag
       61 tttttgttac cttgttttta aaaaatggtt gacatcgact cctatatgag tataatagtt
      121 atcatacatt agaaaagagg ttaactattt tgaaaaaagc tcacgtttat gctatccctg
      181 ctattggggc tgctctcatt gctgctttgg cacaaatcag tcttccaatt ggacctgttc
      241 ccttcactct gcaaaacttt gcaatcggct tgattgctac tgtctttaga ccgagagagg
      301 ctgtactttc tgctggactc tatcttcttc taggtgctat cggtcttcct gtctttgcag
      361 gaggtggagc tggttttcag gctttagttg gccctactgc aggctatctt tggttttatc
      421 tcgtttactc tggacttact tcctctctaa ccaacagcaa gagtggtgtt gttaagattt
      481 ttcttgcaaa cctcttgggt gatgcccttg tctttgtcgg cgggattctc agcttgcatt
      541 tcctagctgg aatggcattt gaaaaagctc ttgctgtggg ggttcttccc tttatcattc
      601 cagaccttgg caaacttctg gctattagtt ttattagccg tcccctactt caacgcctta
      661 aaaatcaggc ttactttact aactaaaaaa ggatatcgag ttatcatgac tcaatatcct
      721 tttcttttat tttgaaaact tatactcaat gaaaatcaaa gagcaaacta gaaagctagc
      781 cgcaggctgc tcaaaacact gttttgaggt tgtggatgaa actgacgaag tcagtaacca
      841 tacatacggc aaggcaaagc tgacgcggtt tgaagagatt ttcgaagagt attagttgcc
      901 tttaaaggca tccaccatcg tttgaaattc ttcatttgag agagtaatcc ctttgcccat
      961 tttagtatgg tctggactcc aagcacgaat atcaaacttt gcaggggcac cattaaagct
     1021 cacacggtta atttccttgg tccaaccttt ttcgttttca gaaagagtca acaagtgctc
     1081 ttcgatttca aatgtaaatt ctgccatttt cttctccttt tttagtttca ttagtttatt
     1141 cgtaaaatct tgtagatttt aggaaaattt tatataatat tgatataaaa gaagggaggc
     1201 caatatgaga cataaattcc agcaagttct aaataaaata catgattttt taaatggata
     1261 tgaccaacct gaccagactg aaaccaactc ccttacagcc actattgaag aggctatcca
     1321 gaaacaaacc gctgttcacc ttatcttgtc tgagacaagt tttacaggtg atatcatcaa
     1381 atatgatcag caaggccagc aaattatcgt gaaaaatttt gccaaaaatg tgagccggat
     1441 tatccgtata agcgatattc aacgcctgcg atttgtcccc tcaactgtcc aaacagccca
     1501 aaaaaataga tttaagaaag agtgagatgt agttgcttca tcccactctt ttttcttagc
     1561 gaatttgttc aaaatgtaaa tgaactgcaa tatgatctcc ataaccactt ctttccaagt
     1621 cacgttgtaa acgataggaa atgtagtgtt ctgcaatggt aatgtaacct gcgcccaata
     1681 aacgatgttc aaccatagat tgaatcatac tgatagtcgc acgttccacc ttggcttctt
     1741 gtaaatccaa aactaccttc ttagtgactt gagcaagatt ttgacgcaaa tcatctgtca
     1801 aaacataaac agtttgggct gccttcaaga tggcttggta aatcttatct ggattaaatt
     1861 cagcaatttc gccattacgt ttgattactt gcataggttt ctcctttatt ctttgttttc
     1921 tttgatttct gccagcattt tttcttcttc tactgtcagt tgataatgtt caagtaaatc
     1981 cggtctgcgc tcgtaggttt tctttaaact ctcgtacaat cgccactgac gaatcttttc
     2041 atggtggcca ctcatcaata catctggcac gaccatgcct cgataatcat agggacgtgt
     2101 gtactgagga tattctaaaa gacctgaaga aaaactatca tcttggtggc tagactcctt
     2161 gccaatcact tctggaatca ggcgaactgt agcatcaatc atggtcatag ctgccaattc
     2221 tccaccagtg aggacatagt cgcctaggga aatctcatct gttaccaagg tcttaatgcg
     2281 ctcatcataa ccctcatagt gcccacagat aaagattagc tcttcctctt gagccaaatc
     2341 ttcagcataa gcctgatcaa actgctttcc agcaggatcg aggagaataa cgcgcggatt
     2401 tttcttttca atagcatcaa aggaatcgaa aataggttgt gctctgagca acatgccctg
     2461 accgcctccg tagggctcat catctacatg acgggccttt tcagcatttt ctcgaaaatt
     2521 atgatactgg atatccaaga gccctttttc tcgagccttt ccaacgattg agtgctccag
     2581 tggagaaaac atctctggaa agagggttaa aatatcaatc ttcatcgtct aacccttcta
     2641 agatttccac atcgacccgt ttatttggaa tatcaacatt gagaaccact ggtgggatat
     2701 aaggtaaaag caaatcacgt ttgccttttc gtttgaccac ccagacatca ttagcacctg
     2761 gttgcaggat ttccttgatg gttccaacca agctatcacc ctcatagact tccaaaccga
     2821 taatctcgtg atagtaaaat tcaccatcgt ctaggtcatt caaatcttcc tcagcgacct
     2881 tgagactata tctcttgtac ttttcgatag tattgatatg gtacatatct ttgaatttaa
     2941 taatgtcaaa gttcttctgt ttacggtggc tagcgatggt cactgtttgg acaaactgat
     3001 ctttttcatc aaacaaagcc agctcagctc cttttttaaa ccgttcttct gcaaaatccg
     3061 tcacagacaa gactcgcatc tcaccctgta atccctgcgt attaacgatt ttcccaacat
     3121 taaagtagtt catcttgtct cctgtaatct ccttttttcc atcttattct gacaattctc
     3181 gaataatagc cgcaattttt tccgattctg accattgtaa ataatggtga ttccctccta
     3241 aaatgagttt agtattggaa gtccaatatt ctgattctct gtactctttt tctctataag
     3301 gctgacaaaa aacaaataca ggaatatgag cttctataga tacatcctca aaatcttcct
     3361 cagtaatctc tccagatatc tgaaattctg gatcttgatt ttccaactct aagccttttt
     3421 cttgcattaa ttcccagatt tttttattcg tttcaggact aaatgttgct tgagttaagt
     3481 tcttaaaata aagttcagga ccacactcgt caatcagcct catctgctct tccatttctg
     3541 gataaggatt ttctgaaaaa tcagcaaaca tgactttttt agttgtcggt tcaattgcta
     3601 ctaaagtctg acgcttaatt ggtttctcga gtaatttgca agctaaaatt ccactccaac
     3661 tatgtgcaca aagtatatat tcagaaattc ctaattcttc aagtacttca taaaccgcat
     3721 ctgcaagatt atctagattt tttccagctt ggtcatgaat cggactccta cctgtgttcg
     3781 gaaaatcaat tgtcaaataa ccaattgtag gaggaggttt ttcaagtata agtgaaaaat
     3841 tttcataact tggtagcaaa cctgctccgt ttagacaaac tagcactttc ttttgctttt
     3901 gataagtaac agagaggcta ccaatttctg tagatacttc aaacctcttc ataaagaaat
     3961 ccactcattc tatataatga attattaaaa atccttatct tttattttat cacgttccaa
     4021 ggattttctc aagttggagg aaggggacaa catctctact ttcccttcaa aaatccttcc
     4081 aaatcatgtt tatgttggta attaacggct gcggttttgt ctttctcaaa gacagtcttg
     4141 gtaaggtcaa tatgattaat agctacgatt gcgacggtgt agtaaatgat atcagccagt
     4201 tctctggcaa gttcctcgtt cgaatcctat cccttctttt cgaccagagc gcctattcaa
     4261 aacctcggct acttctccga cttcctccac taacttcata aagagacctt catcagtccg
     4321 agactgctgt taatgttcga ttaagtagtc ttggaattgc ctaaacgttc aatcttttat
     4381 agtatattga aactagaata gtacaccttt acttctaaaa cattgttaga aatcgatttg
     4441 actgtcctga tcgatttgtc ctgttcttgt ttcattttac tatatcttct attccacaca
     4501 aaaaagcgag acatccgtcc cgcccttctt atttttcgtc aataacgatt cttacttttt
     4561 tgtattcagt tgggacagag tagacaatcg ttcttatcgc agaaatagtg cgacccttac
     4621 gaccgattac acgacccaca tcgctttgat caagattcaa atgatattcc aaaaattctg
     4681 gtgtatcctc aatcttgata gttaaggcat ctggttgtga aattaagggt ttcacaatcg
     4741 caataatgag attttcaatc gtatccatct gtcaacctac tttaaactta ttttgaaaat
     4801 ttagaatcgt ggaatttttt caatacgcct tcttttgaaa ggatgttacg tactgtgtct
     4861 gaaggttgag ctccattagc caaccatgca agaacgcggt cttctttcaa agttacttgg
     4921 ttttcagcaa caagtgggtt gtaagttcca actgtttcga tgaaacgtcc gtcacgtggt
     4981 gaacgtgaat ctgctacgtt gatacggtag aaaggttttt tcttagaacc catacgagtc
     5041 aaacggattt taactgccat ttttaaagtc tcatttcttt aattttttat ttcggtgaaa
     5101 tagctgagct atttagcaca tgttctatta tagcagattt ctggcatgtg tcaagaaaaa
     5161 aacttgacag actataaatt tcttaaagta tttagaaatt tgttagaata ggaaataaat
     5221 gtttgaaaga tgctatccgt gaatactatt ttagaaaaat tttataaaga acaccaagtc
     5281 aaacccttca tatcgcctga acgagagttg gatacttggc ttctaagtcc caagcccgtt
     5341 cccaagcgaa atatggactt attagtagat gattcactag caggagatat cattttacta
     5401 tggagaatcc agtttggtac ttttaccact gaaacatgat tttaaaaact cccattcgaa
     5461 tatgattcaa aattcgctta gaatcaatgt tttcccgctt tttcaaaaaa taaattttca
     5521 tctaatttaa ataactttca attaagtgtg aattttgctt aaaatcatta aaaagcaccc
     5581 catggtgtga accatgaagt gttgtaaatg ctgtgttgta gctagttctt agcgtttaga
     5641 gaactggcta gctttacgag ctttcttaag atctggtttc caaaatactt tgagtacact
     5701 tatggtattg atgcccctaa acatctaaaa actctggtag aaaaagggta tgctcttgtc
     5761 gaaacttctt ttgactcact tgaccatcta aataatacca tgaaaaagaa tatcctgaag
     5821 aagaagggag ttactggact ttctaaaatg aaatcttgcg acctggatca agcccttcat
     5881 gagcattttt cagaagaaga attagctggt cactttcatg tccttctatg gactttttta
     5941 caatggcatt gctatcacac ccaataccta tctaagcgcc tggttcgtaa actttattgc
     6001 agctcttcct ctaaatttcc taattgttga accaattgcc cgttttatac taagttcttt
     6061 tcagaaacca tttactgggg aagaagttga agaagttgaa gattttcaag atgatgatga
     6121 aatcccaact attatctaag ccagttctgt aaactactaa tatttgaaat ccacttcttt
     6181 ttagggtaca atggtataaa tgaatttttg agaggatcag aatgaaaaaa ctagcaaccc
     6241 ttcttttact gtctactgta gccctagctg ggtgtagcag cgtccaacgc agtctgcgtg
     6301 gtgatgatta tgttgattcc agtcttgctg ctgaagaaag ttccaaagta gctgcccaat
     6361 ctgccaagga gttaaacgat gctttaacaa acgaaaacgc caatttccca caactatcta
     6421 aggaagttgc tgaagatgaa gccgaagtga ttctccacac aagccaaggt gatattcgca
     6481 ttaaactctt ccctaaactc gctcctctag cggttgaaaa tttcctcact cacgccaaag
     6541 aaggctacta taacggtatt accttccacc gtgtcatcga tggctttatg gtccaaactg
     6601 gagatccaaa aggggacggt acaggtggtc agtccatctg gcatgacaag gataagacta
     6661 aagacaaagg aactggtttc aagaacgaga ttactcctta tttgtataac atccgtggtg
     6721 ctcttgctat ggctaatact ggtcaaccaa acaccaatgg cagccagttc ttcatcaacc
     6781 aaagctctac agatacctct tctaaactcc ctacaagcaa gtatccacag aaaattatcg
     6841 aagcctacaa agaaggtgga aaccctagtc tagatggcaa acacccagtc tttggtcaag
     6901 tgattgacgg tatggatgtt gtggataaga ttgctaaggc cgaaaaagat gaaaaagaca
     6961 agccaactac tgctatcaca atcgacagca tcgaagtggt gaaagactac gattttaaat
     7021 cttaaaaacc aaaaaaatac agtatccaca ttcggtactg tatttctttt actctcattc
     7081 ttaagttaaa ttattaaaat cccatatttg gtctatccag ccttcataaa agtctggctc
     7141 gtggcagacc ataaggatag atcccctata ttctttgaga gcgcgtttga gctcatcctt
     7201 tgcatccaca tccaaatggt tggtcggctc gtccagcact aaaacgttgt tttcacgatt
     7261 catcaagaga cagaaacgaa ccttggcttg ctctccccct gataatactt gaatctggct
     7321 ttcaatatgt ttggttgtca aaccacaacg ggcaagggct gcacggactt ctgcttgatt
     7381 aagggcagga aaggcattcc agacagcttc aagaggagtt tggcgattac cgccttctac
     7441 ttcctgctca aaataaccaa gttctaaata atctccacgc tccacttccc cagcgattgg
     7501 cgagataatg cccaagagac tcttcaagag agttgttttt ccaataccat tagcaccaat
     7561 aatcgcaacc ttttgattgc gttcgaaggt aagatttaaa ggcttagtaa gaggaaggtc
     7621 gtaaccaatt tgcaagttct tggcttggaa gataaagcgc cctggtgtac gagctggttt
     7681 gaaatcaaag gatggttttg gtttctcact ttggagttcg ataatatcca tcttatccaa
     7741 tttcttttga cgagacatag ccatattacg agttgcaaca cgggctttat tacgagccac
     7801 aaagtccttg aggtctgcaa tctctttctg ctggcgttcg taggctgcct ctagctgaga
     7861 tttcttcata gcataaactt cttggaactg gtagtagtca ccagagtaac gcgtcagctg
     7921 ttgattttcc acatgataga caatattgat aacgtcattg aggaatggaa tatcgtgcga
     7981 aatgagaaca aaggcattct catagttttg gagatagcgc ttgagccaat caatatgctc
     8041 agcatccaag tagttggtcg gctcgtccaa cagcaagata tcaggctttt caaggagaag
     8101 ttttgccaaa agcaccttgg ttctttgccc acctgacaaa gaagttacat ccgtatccat
     8161 gccaaagtcc ataacaccaa gagcacgcgc tacttcgtca atcttagcat ccaaggtata
     8221 gaaatcacga ctctccagac ggtcttgaag ttctcctact tcttccatga gagcatcaac
     8281 atccgcaccg tcttcagcca tttccatata gaggtcattg atacgagctt cagctttgaa
     8341 aagctcatca aaagccgtac ggagaacatc acgcaccgac tgtctttcag caaggacaga
     8401 gtgctgatcc aagtaaccag ccgtcacata tttggaccac tcaacctttc cttcatctgg
     8461 cagcatttta ccagtcacga tactcataaa ggttgatttt ccttcaccat tggcaccgac
     8521 caggccgata tgttctccct tgaggagacg gaaggacaca tcttcaaaaa ttgcacggtc
     8581 accaaaaccg tgactcagat ttttaacttc taaaatactc attttaattc cttatcttgt
     8641 ttttatgtaa tcgtttataa aggagccaag ccagatagcc acccaaagtg ttggtccaca
     8701 aatcatcaat ctcaaagacg cgattgaaat caaagaaaaa gtccaagatt aattgcgtac
     8761 actcgattcc aagactcaca agaaaactaa aaagaaggac cttttttgtt ttccgcaaat
     8821 ttggaaatag ataaaggagt tggaaaatca gaggaaaaaa caagaagaca ttgaggatat
     8881 tttgtaaaaa aatccaacat aattgtccaa tgtcactcac ttcgcccagt ttccagagag
     8941 aattgaaagg agtcaaaaga aaaaccaggc gtccaagatg ctgaatatct ggagttccca
     9001 ctcccacggt agattgttct tgaggagtaa agcaaaaata gacaatgcaa atgctataga
     9061 aaatgactcc ccagaccaaa atatgattat aagtcttctt catcattaag gatttaccgc
     9121 tgcgactgcc ttctggcggt cacgtttcat tgtgttaaag agcaattgtc cacaagctgc
     9181 gtcaatatct gtaccatgct cttgacgaac cacacagttg cccccttttt tcttaagcgt
     9241 atcatagaaa gccaacacgc gctctttggg actacggcta tattggtcat gctcactaac
     9301 tgggttataa ggaatcaagt ttacataaga cgatttcttg atgttcttga gcaattcagc
     9361 caattccaag gcttgttcca caccgtcgtt gacttcatta agcatgatat attcaaaggt
     9421 tacacgacgg tttgttgtct caatgtagta ttcaatagca gcaaagagtt t
//
LOCUS       DAVBCA010000072         9136 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.072, whole genome shotgun sequence.
ACCESSION   DAVBCA010000072 DAVBCA010000000
VERSION     DAVBCA010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9136)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9136)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9136
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.072"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            1..294
                     /locus_tag="VQU19_001864"
                     /pseudo
     CDS             1..294
                     /locus_tag="VQU19_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466308.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            370..819
                     /locus_tag="VQU19_001865"
     CDS             370..819
                     /locus_tag="VQU19_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000337416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET2481070.1"
                     /translation="MCTILVSIYYKIGLSSSGVYKAVADGEMTVSLSYEDPAVKLLND
                     GANIKVVYPKEGTVFLPASAAIVKKSKNMENAKKFIDFIISQEVQDTLGTTTTNRPVR
                     KNAKTSENMKPIDKIKTLTEDYDYVIKNKSDIVKKYNEVFTDIQSKQ"
     gene            832..1491
                     /locus_tag="VQU19_001866"
     CDS             832..1491
                     /locus_tag="VQU19_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2481071.1"
                     /translation="MSEIEIINAKKIYHDVPVIENLNITIPKGSLFTLLGASGCGKTT
                     LLRMIAGFNSIEGGEFYFDDTKINNMEPSKRNIGMVFQNYAIFPHLTVRDNVAFGLMQ
                     KKVPKEELIQQTNKYLELMQIAQYADRKPDKLSGGQQQRVTLACALAVNPSVLLMDEP
                     LSNLEAKLRLDMRQAIREIQHEVGITTVYVTHDQEEAMAISDQIAVMKDGVIQQIGRP
                     K"
     gene            1618..1923
                     /locus_tag="VQU19_001867"
                     /pseudo
     CDS             1618..1923
                     /locus_tag="VQU19_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809465.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TOBE domain-containing protein"
     gene            1913..3558
                     /locus_tag="VQU19_001868"
                     /pseudo
     CDS             1913..3558
                     /locus_tag="VQU19_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(3661..4353)
                     /locus_tag="VQU19_001869"
     CDS             complement(3661..4353)
                     /locus_tag="VQU19_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET2481072.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEMIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGCEKMEEGSI"
     gene            complement(4597..5934)
                     /locus_tag="VQU19_001870"
     CDS             complement(4597..5934)
                     /locus_tag="VQU19_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HET2481073.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPDINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALTETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGAAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     IGDSVARVLEEMGLETVGTHGTTVALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            complement(5944..6210)
                     /locus_tag="VQU19_001871"
     CDS             complement(5944..6210)
                     /locus_tag="VQU19_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HET2481074.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            complement(6475..6861)
                     /gene="rplQ"
                     /locus_tag="VQU19_001872"
     CDS             complement(6475..6861)
                     /gene="rplQ"
                     /locus_tag="VQU19_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HET2481075.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            complement(6873..7808)
                     /locus_tag="VQU19_001873"
     CDS             complement(6873..7808)
                     /locus_tag="VQU19_001873"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HET2481076.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            complement(7851..8234)
                     /gene="rpsK"
                     /locus_tag="VQU19_001874"
     CDS             complement(7851..8234)
                     /gene="rpsK"
                     /locus_tag="VQU19_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HET2481077.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            complement(8252..8617)
                     /gene="rpsM"
                     /locus_tag="VQU19_001875"
     CDS             complement(8252..8617)
                     /gene="rpsM"
                     /locus_tag="VQU19_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HET2481078.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            complement(8635..8751)
                     /gene="rpmJ"
                     /locus_tag="VQU19_001876"
     CDS             complement(8635..8751)
                     /gene="rpmJ"
                     /locus_tag="VQU19_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HET2481079.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            complement(8776..8994)
                     /gene="infA"
                     /locus_tag="VQU19_001877"
     CDS             complement(8776..8994)
                     /gene="infA"
                     /locus_tag="VQU19_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HET2481080.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
BASE COUNT         2766 a         2044 c         1567 g         2759 t
ORIGIN      
        1 tcaaaagaaa atgataatgt tatcaaagaa tatcaaaaca caactggctt ctctactcct
       61 tatacactag atggtagtgt tttaatcgtc caccctgatt taactaaagg catgaacatc
      121 gaaggatata gcgaccttct caaacctgaa ctaaaaggaa aaatcgcaac tgctgaccca
      181 gcaaactctt ctagcgcctt tgctcaatta acaaatatgc tacaagctca aggtggttac
      241 aaagatgata aggcttggtc ttatgtaaaa gatcttttca cacttattga tggtatagta
      301 aaatgaaata agaacaggac aaattaatca ggacagtcaa atcgatttct aacaatgttt
      361 tagaagtaga tgtgtactat tctagtttca atatactata aaatcggttt aagttcatct
      421 ggtgtctata aagcagtcgc tgatggagaa atgactgtta gtctctctta tgaagatcca
      481 gcagttaaac tcttaaatga cggagctaac attaaggtag tctatccaaa agaaggaacc
      541 gtcttcctac ctgctagtgc tgctatcgtt aaaaaatcta aaaatatgga aaatgccaag
      601 aaatttatcg attttattat ctctcaagaa gtacaagata cacttggtac aaccactact
      661 aaccgtcctg ttcgtaaaaa tgctaaaaca agcgaaaaca tgaaaccaat tgacaaaatc
      721 aaaacactca ctgaagatta tgattatgtc atcaagaata aatcagatat cgttaagaaa
      781 tacaacgaag tctttacaga tatccaatct aaacagtaaa agaggttcac tatgagtgag
      841 atcgaaatta ttaacgccaa aaaaatctac cacgatgtcc ctgttattga gaatttgaac
      901 attacaattc caaaaggaag tctctttacc cttcttggag cttcaggatg tgggaaaacg
      961 acccttcttc gtatgattgc aggtttcaac agtatcgaag gtggagaatt ttacttcgat
     1021 gatacaaaaa tcaataatat ggaacccagc aaacgcaata tcgggatggt tttccaaaac
     1081 tacgctattt tcccacattt gactgtccga gacaacgttg cttttggtct tatgcaaaag
     1141 aaggttccaa aagaagaatt gattcaacag accaacaagt atcttgaact catgcaaatt
     1201 gctcaatatg cggatcgaaa gcccgataaa ctcagtggtg gacaacaaca acgtgtcacc
     1261 ttggcatgcg ccttagcggt taatccaagt gttctcctca tggacgagcc acttagtaat
     1321 ctggaggcca aacttcgctt ggatatgcgt caagccatcc gagaaatcca acacgaagtg
     1381 ggaattacaa ctgtttatgt aacccacgac caagaagaag ccatggctat ttcagaccaa
     1441 attgctgtta tgaaagatgg ggtgatccaa caaatcggcc gaccaaaata actctatcat
     1501 aaaccagcta atgagtttgt ggcaaccttt atcggacgca caaatattat ccctgccaat
     1561 cttgaaaaac ggagcgacgg cgcttatatc gtcttttcag atggctatgc ccttcgaatg
     1621 ccagctcttg atcaggttga ggagcaagct attcatgtaa gcattcgtcc cgaagagttt
     1681 atcaaagatg aatctggaga tatcgaagga actattagcg atagcgtcta tcttggacta
     1741 aatacggagt atttcattga gacaggtttt gcctcaaaaa tttaagttag tgaagaatca
     1801 acttttgaag aagaactaca aaaaggcaat cgtattcgtc tacgaatcaa tacgcaaaaa
     1861 ttaaacatct tttctgcaga tggttcccaa aacctgataa aaggagtcaa ccatggaatg
     1921 taaaaaacta aatatttgga cagcttcctc tttcttcatc tttcttacct atcttgtctt
     1981 tctcgtttat cctatcgtta ccgtgctcaa gcaagcactt atacatgaag gacaattctc
     2041 actagctaat tttgtcactt tctttagtaa agcctactac tctgagacac tagtcaacag
     2101 tttcaaggtt tccattaccg ctactatcac ttccttagtt gtaggaaccc tattagctta
     2161 tctcttctct atgtatgact tcaaggggaa gaaatttcta caaatattga ttatcattgc
     2221 ttccatgtca gctcctttcg taggagccta ctcctgaatt ctcttgctgg gacgaaatga
     2281 ggtcatcact aaatttttga caaatgccct tcatcttcca gctatcgata tttatggatt
     2341 caaaggaatt gtacttgtct ttacactgca actattccca ctggtatttc tatatgttgc
     2401 tggaacaatg aacagtattg acaattctct acttgaagca gctgaaagca tggggtcctt
     2461 cggatttaag cgtatcgtaa cggttgtttt acctctccta gttccaacct tactagcagc
     2521 tccttgcttg tatttatgag agcattctca gactttggaa cgcctatgtt gattgacgaa
     2581 ggatatcgga ctttccctgt cctgatttat acccaattta ttagcgaggt tggaggaaat
     2641 tctgcttttg caattatggc gattatcatt gccttggcaa ttttccttat ccaaaaacac
     2701 attgcaaacc gctacagttt cagcatgaat ctgctccatc caattgagcc taaaaaaact
     2761 acaaaaggaa aaatagctgc catttatgca acagtctacg gaattatctt tatctctgtt
     2821 ttacctcaaa tctacttaat ttatacctct ttcctaaaaa catcaggtat ggtatctgtt
     2881 aaaggttatt ctccaaacag ttacaaggta gctttcaatc gtatgggatc tgctattttc
     2941 aataccattc gtatcccttt gattgcctta gttctagttg ttctatttgc gacatttatc
     3001 tcctacctag ccgttagaaa acggaatttg tttacaaact taattgacag cctcagtatg
     3061 gtaccttata ttgtaccagg aaccgttcta gggattgcct tcatttcttc cttcaatact
     3121 ggtctatttg gaagtggatt tcttatgatt acagggactg ctttcatctt gattatgtct
     3181 ctatctgtca gaagattacc ttatactatt cgctcatctg ttgctagctt acaacaaata
     3241 gcaccaagta ttgaagaagc tgctgaaagc ttaggaagta gtcgtctcaa tacctttgct
     3301 aagattacaa ctccaatgat gctatctggt atcatttctg gagccatctt atcttgggtc
     3361 acaatgattt caaaactctc tacttctatc ctcctctaca atgtcaaaac aagaacaatg
     3421 actgtagcta tttatacaga ggttctcaga ggaaattacg gtgtagccgc agccttgtca
     3481 actatcctga ctgttctaac agtaggttcc ttgctcttgt ttatgaaaat ctctaaaagc
     3541 aatagcatta cactttagtt ttccacatca aaaacagccg aaaggagtgc cctcggctgt
     3601 tttttcttat cttgatattc ttatcaaatc cctagctcat ggcaagcaag tctagactga
     3661 ttaaatagag ccttcttcca tcttctcaca tcctagctct cggtaactac ggtcaccgac
     3721 aacttcaacc ctaaactgac cgtcctcata ttcaagaatc gtcacgctac cattatctag
     3781 accatgcgga tgcatgccat taatcagata aacaatggtt ccaatagtca ttccatggct
     3841 gacaacaagg gcgttacctc caccttgatc ttccatttct tttgcaatca tttcaaagcc
     3901 ttccttgatt cggccactga gtttttccca gccttcagcc caaccagctg tatcgacctc
     3961 taccaagccc tcagccagtt cagcataaga caattggtga acgtggtcca cattaaagat
     4021 acgaggaata atgcccatga aaagatcgcc atcataggct ccatcaaaac taccgaaaca
     4081 ccattctctg atacgcttgt ccatgcgata agggattttc ccctgcaagc caagttcttc
     4141 aaggataatt cccatggtct gaatggtacg accagaatca ctcgaataag cgcgctcaaa
     4201 ctgtagatca gattctcgca aaccgattcc taactcttga atccctcgtt caccttcagc
     4261 agttaaggga gtatcgctcc aaccttgcgc gcgaccaatc gtgttaaaca tggtcttgcc
     4321 atgacgtacc aaatacaatc gtacttttac cattttccgt cctccgtttg cttctattat
     4381 atcatgaatg ataaaataaa agccacccat acaggcgact tttgaaggag attattatga
     4441 aaaagtttag gagttcatta aataaagata ttagatgaaa atcaaattca aactaattca
     4501 gtgttatctg tttcaaataa tattaggagg tctttattta atgattatag tatacacatc
     4561 taatcttaaa tagaacttaa aatttctcct attttcttaa tttttaaaac tatgaattgg
     4621 tgctgggatt tgtccaccgc gagagatgaa gtcgacagac gaagccccat taaccttcat
     4681 aacaggtgca gttcctaata gaccaccaaa ctcaatcata tcgccttctc ttcctttggg
     4741 aatgatacga acagctgttg ttttcatgtt gataacaccg attgctgctt catccgcaat
     4801 catagccgca atggtttcag caggcgtatc ttctgggatg gcaatcatat ccaatccaac
     4861 agaacagata gccgtcatag cttctagttt ttctaaatta agagagccat tttgcactgc
     4921 agcaatcatt ccttcatcct cagaaacagg gataaaggcg ccagataaac caccgacttg
     4981 gttgcaggcc atcactccac cctttttaac ttggtcgttc aagagggcca aggcaaccgt
     5041 cgttccatgc gtgccaactg tttctagccc catttcctca aggacacgtg ccacagagtc
     5101 tccaatcgca ggggttggtg ccaaactcaa gtccacaata ccaaactcca cacccagtct
     5161 ctcactggcc atttgaccaa ccaattgacc gatacgagtg attttaaagg cagttttctt
     5221 aactgtttcg gctactacat caaagctctg tccacgaact ttttccaaag cacgtttcac
     5281 cacaccagga ccagaaactc cgacattgat gataacatct gcttccccaa caccatgaaa
     5341 ggcacccgcc ataaatggat tgtcctcaac agcattagcg aatacaacca acttagccgc
     5401 tcccatatct gaaagatttg ccgtttcctt gataattcgt cccatatctg ccacagccgt
     5461 catattaata ccagacttgg ttgagccgat attgactgac gagcagacct tatccgtctc
     5521 agtcaaagcg cgaggaatgg aattgatgag aatctcatct cccttttgat aacctttttg
     5581 tactaaggca gaaaaaccac caataaagtc cacaccaatc tctttcgcag ccttatcaag
     5641 cgcttttgcc agaaccacgt agtccgtcgc atctgtcgct gccccaatca gagaaatagg
     5701 tgtcaccgat acacgcttat taacgatagg aattcccaac tcagccgcaa tttcatcacc
     5761 aacagctact aaattagccg cctttgtcgt aattttttga tagattttct ccgcagcacg
     5821 attgatatct ggatcgatac agtccaaaag agaaatcccc atggtaatgg ttctaatatc
     5881 gaagttttgc tcctcaatca tggcgatggt ttcagtaact tgtctaatat ccatgatgac
     5941 ctcctagata ttatacatag cttcgaaaat cgctgcactc tgaatattga tttttacatt
     6001 caaagtttgc ccaaaagctt caaattcatt acgaagatag gtaaaatctt gcttttcatc
     6061 actagataca acagccatca tcgtaaaata ttcatccaag acagtttgag agatatcgtc
     6121 aatattcaat cctaattctg caattttacc agaaacacct gcaacaattc cagatttatc
     6181 tttaccaaca acagttataa tggctttcat aagtaaactc caattcttct taaaataaga
     6241 aaccttaaca ttaaacagga ttcttttcaa atagtatagc ataattctaa cgaaaatact
     6301 caaaaacgcc tgcttacgaa gttgttctta agaaaaaaac aatttcgtaa acaagcgtct
     6361 actatcccaa cttatgatga gtgttcccgc taggaccgaa atcctagcgg tagaccagag
     6421 ctagactaag agcacaagac tccatcatca taacactcaa caaaattgat gattttatac
     6481 taattcgatg atcgccattg gcgctgcatc accacgacgt ggttcagttt taaggatacg
     6541 agtgtatcca ccgttacgtt cagcataacg aggtgcgatt tctgagaaca atttttgaag
     6601 tgctgtagta gaagtgtact tatcagttgc ttcatcatag ttttcagatg cgatttcatt
     6661 acgtacgaaa gcagctgctt gacgacgtgc atgcaaatca ccacgtttac ctagagtaat
     6721 cattttttca acagttttac ggatttcttt agcacgagct tcagttgtca cgattgattc
     6781 gttgatcaaa aggtcagttg tcaaatcgcg aagcattgct ttacgttgtg agctagtgcg
     6841 tcctagttta cggtaagcca tgtattcctc ctttatttat cttttaatcc aagacccaaa
     6901 tcaatgagtt tgagtttcac ttcttccaaa ctcttgcgtc caagatttcg tactttcatc
     6961 atctctgctt cagatttttc tgtcaaatca tgcacagtat tgataccggc acgttttaaa
     7021 cagttgtatg aacgcacaga caagtccagt tcctcaatcg tacgatctaa aatacggtcg
     7081 tcagattcag tatcagcttc tttcatcact tcagttgact tagcaatctc agtaagattt
     7141 gtaaacaaat caagatgttc tgtcaaaata cgtgctgaaa gccctaaagc atcttctgga
     7201 ataattgttc catttgtcaa gatttcaagg gttaatttgt cgaaaccatc attgctacct
     7261 acacgagcag gttccacttg atagttgact tttgtaactg gtgtataaat agaatctaca
     7321 gcaagtgttc caactggtgc attatccttt ttattttcat cagcaggtac atatccacga
     7381 ccactgttaa cagtcatagt cgcttttaga gaagaacctt caccaattgt aaagagataa
     7441 tgatctggat ttacaatttc aatatcgcta tctgtcaaaa tgtcaccagc tgttacttca
     7501 gcaggacctt caacatccag ttcgatgatt ttttcgtctt caacgtacga tttcactgca
     7561 attcctttaa tgttcagaat gatttgcatc acgtcttcac gaacacctgg aactgtgtca
     7621 aactcatgta acacaccatc aatgttgata gatgtcacag ctgctcctgg tagagaagct
     7681 agaagtacac gacgaagaga gttaccaaga gttgtaccgt agccacgttc aagtggttcg
     7741 attacaaact tgccataatc tttattttca tcaatttttg ttatatttgg tttttcaaac
     7801 tcgatcattt agttactccc tcttaaacga aaagcagtgt aatgcgatga ttatacacgg
     7861 cgacgttttg gaggacgagc accattgtgt ggcactggag tcacatcacg aattgctgtt
     7921 acttcaagac cagcggcagc aagcgcacga atagctgact cacgaccaga acctggacct
     7981 tttacagtaa cttcaactga tttaagaccg tgttcttgtg cagatttagc agcagcttca
     8041 gaagccattt gagcagcgaa tggtgtagat ttacgagaac ctttgaaacc aagagcacca
     8101 gctgatgacc aagcaattgc attaccatgc acatcagtaa tcataacaat agtgttatta
     8161 aatgtagcgt gaatatgagc aataccagat tcgatattct ttttcacacg acgtttacgt
     8221 gttggtttag ccaagacttt tacctcctat attatttttt cttaccagca atcgcaacag
     8281 ctttaccttt acgagtgcga gcgttgtttt tagtattttg tccacggaca ggaagtccac
     8341 gacggtgacg gataccacgg tatgaaccga tttccatcaa acgtttgatg ttcaagttta
     8401 cttcacgacg aaggtcacct tcaactttga ttgcatccac ttcacgacgg atagcatctt
     8461 cttgatctga tgtaagatca cgtacacgaa catcttctga gattccagca gcagccaaaa
     8521 ttttcttaga tgttgcaagt ccgataccat aaacataagt caatgagatt actacgcgtt
     8581 tgtcatttgg aatatcaact ccagcaatac gagccatgtt ttctcctttc tatcttatcc
     8641 ttgacgttgt ttgtgttttg gatttgctgg gcaaattacc ataacacgac cattacgacg
     8701 aataacttta cagtattcgc aaattggttt gaccgatggt cttactttca tttcttatcc
     8761 ctccaagttt ttcgattatt taaagcggta agtgatacgt ccacgtgtca agtcatatgg
     8821 actcatttcg acagtaacac gatctcccgc taaaatacga atatagtttt tacgaatttt
     8881 accagaaact gttgctaaaa tctgatgtcc attttcaagt tcaaccgtaa acattgcatt
     8941 cggcattgta tcaactactt tgccttcaac ttcaatcaca tcgtcttttg ccacgcaaaa
     9001 gcacctccat aaatttcgat tcgatgcctc tagacacaga gacaacaatt ataagtcaga
     9061 ctatctcagt ataacatttg tagcggattt ttgcaagtgc gaaaaacgct ttatttcaaa
     9121 tttgtcaata cttttt
//
LOCUS       DAVBCA010000073         9123 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.073, whole genome shotgun sequence.
ACCESSION   DAVBCA010000073 DAVBCA010000000
VERSION     DAVBCA010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9123)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9123)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9123
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.073"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            168..854
                     /locus_tag="VQU19_001878"
     CDS             168..854
                     /locus_tag="VQU19_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET2481081.1"
                     /translation="METKKIKNLKGQIIVSCQALEGEPLYTPNGGVMPLLAKAAFQAG
                     AKGIRANSVRDISEIKEEVDLPIIGIIKRDYDGFEPFISATMKEIDELVSEGVDILAL
                     DCTNRSRPGYDNITDFIHDIKVKYPNQLLMAAISTFEEGKVAAESGVDFVGTTLSGYT
                     PYSPKKDNPDFELVERLVKELDVPVIAEGRISTPEQARKMLDLGAYAVVVGGAITRPL
                     EIAKKFIEVV"
     gene            855..1787
                     /locus_tag="VQU19_001879"
     CDS             855..1787
                     /locus_tag="VQU19_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001071049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2481082.1"
                     /translation="MNQEILKKSKIQLTVEHIQKYWILYLMMIPATVLLILFTYGPMY
                     GIIMAFQDFTVFKGYTGSPFVGLKHFQRLFSDPLFYRLFKNTFMVGVLDFLFFFPAPL
                     IFALILNEVRKVRFKSVVQSISYLPHFIPLVVMVGIIFELFGSYGIINSLLSSLGMEP
                     ISFFTKSEWFLPLYIGSGVWKTIGWGSIIYMGALTNIDSTLYEAADMDGANRWHKMWH
                     VTLPSLRPTVVTLFILNAGGIMQVGFEKVFLMSSPATYEVSDVLSTYVYRQGILNSDF
                     SYSAAVGLFNNIVALLFVLLANKIAKKLGEEGIV"
     gene            1798..2727
                     /locus_tag="VQU19_001880"
     CDS             1798..2727
                     /locus_tag="VQU19_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000577774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET2481083.1"
                     /translation="MIFSKNTKKSNRDKETFVDYLFIFILIIITLLMLYPLWWVVMTS
                     LSEPVWLSKNVVKLFPLKIDITAYKFIFGDSKLWQAYGNSVLYAALSTIVSVAVCSMY
                     AYPLTIPEIRGKKFWNTLILIPMFFSGGMIPLYIQVANLGLLNTAWALVLPGAVSTYY
                     IILFRTQFKSIPMELRESARIDGASEFRIFWNLVLPLSKVIFMIIALYCIVGSWNSFT
                     PPLLYLNDDTKMPLSIYLRNLVVTNTTDTAELSLSAGNTYYQQIAAQGGGIGMRIAIK
                     MGTIVVSVIPIMMIYPFIQKHFVKGILLGSVKG"
     gene            2741..4180
                     /locus_tag="VQU19_001881"
     CDS             2741..4180
                     /locus_tag="VQU19_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001178946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2481084.1"
                     /translation="MQNLKKYLLLDSGLVVGYTLENAQLKLNKLKKDTENNPLFGEEY
                     FAENPKLWEVRFDNSYPNVIYDKELKLYRCWYQTFVSDEASEETPLAERGEKEYIVKS
                     SRMTALCYAESKDGVKWEKPNLNLVKFKGSKDNNIVLMHAHGAGIMLDEQELDPKKRY
                     KLVSKLEFSPNLHYMVVVFSEDGIHFDEPIPWKKWNPAADSHNFPFRDPKTGKYAVIT
                     RTWANNVRLSAITFSDDFINWSEPKEILRGDGFEDQIYSMPVISYADIYLGFASMYHE
                     GDTLNENYDKVDLELKFSANLEQWDSVCKGDYLIERGGGVYPQNADFDASCIFTAAPI
                     IEDDKIWFYYMGGNGNHTGFRESSLARGYIKKDQFAYYTNKREGIPAKISTVSFQTYD
                     DEIYILADIPENGYIKVAVGTKYGNAYSDFGQEDISLVQVSDGKYKLEFNKKSILDLG
                     NSPVAFKFEIENAKLYGIEGSIQQHYLKY"
     gene            4249..5826
                     /locus_tag="VQU19_001882"
     CDS             4249..5826
                     /locus_tag="VQU19_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET2481085.1"
                     /translation="MVKLNKVLKGSVAFLSASLLLAACGNNANSKPAEKTADGKTKIS
                     FLSTWQINDVRPPKDETLVGQWLEEQLGIDIDLVTIPGEGVSSKVNSLITSNQLPTVL
                     LTTGDKSDIAGINKLGKQGAFLDLSQHMDKLPNYKKYLEKNNALAQIEDDEKHIYAFT
                     KFFTDENIMYTTPILRKDLLVGSEFEDLSKIKTVDDYTKVLKYLTEKQGSPAFIQRNG
                     YEGFMKRVTPLWNLSHRTYYDYESDSYKHPVEQPQLKQFVEWLKELRKDNVLHPDWAV
                     MKDETWEGLLASNKGSFTVDRMNIIGDNNFDKSFDWQPLVYPEINGKRYLQPKTPYIS
                     DSGWVINANAPKEEIDKALEFFNFLYADENQEKLAIGFEGKTFTRENPNTQAGIKWLI
                     QIYGENAGNDKAELLFKHGNQAFTRVQTKLDIEAQPGTFPKVMYDQVDKIKKDLGGFR
                     PDTPVLSFTTEELDVLTKSEAGLNTFFDENIIKFIEGQRDMSEWDSFINEAKSKDLDK
                     VTKVYNDAYKRVKDRMK"
     gene            5886..7346
                     /locus_tag="VQU19_001883"
     CDS             5886..7346
                     /locus_tag="VQU19_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HET2481086.1"
                     /translation="MYDVVIIGAGSSGALAAIASGRLGLKTCLIEKGSRIGGVPINTL
                     MGSFANLYFDDSGRVNASKIVGELIERIIKKGGTVFNSMEELMNVNDFYQITIPYQPE
                     VYESVLTDMLIESKVDILLNVEVNNIIYDSKNIKSLEILSNQEVKLIDSKVFIDATGN
                     ATIASASGADVYEKNSSYGCLMRVGGVDISKTIEHIEKTKQWNYIEGYNQWLEEVLAN
                     RKYRATGAVLKDPVSYDHAPMLSKDDHFMNDEKWNYIKERWEKFRFIYTLEVSLFRNE
                     LKKAVESGDFNFEIYHDDKSGVTMNGDGISYGSWGQNVALINVAKAFGFNPKYMEDES
                     HANILSRKYNLTFLSFLKKYVPGFENSFILDQGTRATNRSCRHIDNSSMMDEILDFPM
                     YTFKTMYSYQTPKEITYKSIVGGKLNNLFVIGKGAYQSESFRSQISCMLMGISSAAAA
                     KTIIEDKSNTLNINRDLFKSNLDILFTWEFSNWITD"
     gene            7368..7823
                     /locus_tag="VQU19_001884"
     CDS             7368..7823
                     /locus_tag="VQU19_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001000318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT domain-containing protein"
                     /protein_id="HET2481087.1"
                     /translation="MNDTNKNQYFVYEFDTSFVEMSYSQFFEGYCILFSKEPYPSLSD
                     MPMEFRKEFLMEMSILGDAMLEVLNAYRINYDILGNSTPVLHAHLFPRYMWEEEERRK
                     TVVHRYDSSVFSNPEFEFTIEKHGPIIKKLRSAIDRHYREYQQLLDDSN"
     gene            7910..8315
                     /gene="cdd"
                     /locus_tag="VQU19_001885"
                     /pseudo
     CDS             7910..8315
                     /gene="cdd"
                     /locus_tag="VQU19_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221146.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
     gene            8328..8777
                     /locus_tag="VQU19_001886"
     CDS             8328..8777
                     /locus_tag="VQU19_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET2481088.1"
                     /translation="MELVEFKNGHVNTVHEHIAITKVKEFLNNHDILKDKGGIHKIST
                     DFFYNIIDMETTTEENRPWESHKEYYDVHYLLNGEETILYNFLSQMELSEYKVDDDWQ
                     QMNGTALFSIKLKKDMLLLLEPNDAHRTGLLVEEPLNIKKVVFKVKI"
     gene            complement(8889..9123)
                     /locus_tag="VQU19_001887"
                     /pseudo
     CDS             complement(8889..9123)
                     /locus_tag="VQU19_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT         3154 a         1206 c         1706 g         3057 t
ORIGIN      
        1 gtgtattgaa tctataacag tacgccttaa atgctaaaat atttctataa attaatttaa
       61 ctttcctgat agggctgttc atatcttatt tcaattcact atataaataa aattgtagta
      121 gatgttattg aattagtaaa aaaaataaaa aaacggaggt tttctgaatg gaaactaaaa
      181 aaattaaaaa tttaaaaggt caaataattg tttcctgcca agcgttagaa ggagagccac
      241 tttatactcc aaatggagga gtgatgccgt tattagcaaa agccgccttt caagcaggcg
      301 ctaaaggtat tcgtgctaat tctgtccgcg atatttcaga aataaaagaa gaagttgact
      361 taccaattat aggtatcata aaaagagatt acgatggctt tgaacctttt atttcagcaa
      421 ctatgaaaga gattgatgaa ttagttagtg aaggagtaga cattttagct ttggattgta
      481 ctaatcgttc aagaccaggt tatgataata ttactgactt tattcatgat attaaagtca
      541 agtatccaaa ccaattatta atggctgcta tttctacttt tgaagaaggg aaagtagctg
      601 ctgaatcggg agtagatttt gtgggtacga cattatctgg ttatacacca tatagcccta
      661 aaaaagataa tcctgatttt gagttagttg aaagattggt aaaagagctt gacgtaccag
      721 ttattgctga aggaagaata agtactccgg aacaagctag aaaaatgtta gatttaggtg
      781 cttacgcagt ggttgttgga ggagctatca ctcgtccttt ggaaatagcg aagaagttta
      841 ttgaggtagt ttagatgaat caagaaatat taaaaaagag taagattcaa ttgacagttg
      901 aacatattca aaaatattgg attttatatt taatgatgat tccagcaact gttctactaa
      961 ttttatttac gtatggacca atgtacggca ttattatggc ctttcaagac tttactgtct
     1021 tcaagggata tactggaagt ccatttgtcg gtttaaaaca ttttcaaaga ttgttctcag
     1081 atcctttgtt ttatagattg ttcaagaata cgttcatggt aggggtttta gattttttat
     1141 tctttttccc agctccgctt atttttgcac tcatattaaa cgaagtcaga aaagtaagat
     1201 ttaagagtgt agttcaatct attagttatc ttcctcattt tattccccta gtggttatgg
     1261 ttggtattat ttttgaacta tttggttcat atggtattat taacagttta ctttcatcac
     1321 ttggaatgga gccaataagt ttctttacaa aatctgaatg gttcttgcct ctctacattg
     1381 gttcaggagt atggaaaaca ataggttggg gttctatcat ttatatggga gcattaacca
     1441 atatagattc aactttatat gaagcagcag atatggacgg ggctaataga tggcacaaaa
     1501 tgtggcatgt aactctacca agtttaagac ctacagtagt tactttgttt atactaaatg
     1561 ctggtggtat catgcaagta ggatttgaaa aggtattctt gatgtctagt cctgcaacat
     1621 atgaagtatc tgatgtatta tctacttatg tttatagaca aggtatttta aattctgatt
     1681 tcagttactc agctgcagta ggattattta ataacatagt agctttgtta tttgttttat
     1741 tagctaataa gattgctaaa aaacttggcg aagaaggaat tgtataaggg gggtaaaatg
     1801 attttttcaa aaaatacaaa aaagagtaat agagacaaag aaaccttcgt tgattatctc
     1861 tttatattca ttttaataat aataacctta cttatgttgt atccattatg gtgggtagtg
     1921 atgacgtcac tttcagaacc agtttggcta tctaaaaacg ttgttaaatt atttccctta
     1981 aaaatagata ttactgcata taagtttatt tttggggatt ctaaactatg gcaagcatat
     2041 ggtaatagtg tattgtatgc tgcactatct acaattgtta gtgttgcggt atgtagtatg
     2101 tatgcctatc cacttacaat tcctgaaatt aggggtaaaa aattctggaa tactcttatt
     2161 ttgattccaa tgttctttag tggaggaatg atcccgcttt atatacaagt tgcaaacctc
     2221 ggtttattga atactgcttg ggctcttgtt ttacctggtg ctgtttctac atattatata
     2281 attttgttta gaacacagtt taaatcaatc ccaatggagc ttcgtgagtc tgctagaatt
     2341 gatggggcaa gtgaatttag aattttttgg aatttagtat taccattatc aaaagttatt
     2401 ttcatgatta tagcacttta ttgcatagtt ggttcatgga atagttttac tcctccatta
     2461 ctttatttga atgacgacac taagatgcct ttatctattt atttgagaaa tttagtcgtt
     2521 acaaatacaa ctgatactgc tgaattatca ctttctgcag gtaatacata ttaccaacaa
     2581 attgctgctc aaggtggagg tattggtatg cgtattgcta ttaagatggg tactattgtt
     2641 gttagtgtta ttccaattat gatgatttat ccatttattc agaaacattt tgttaaggga
     2701 atcctgctag gttctgtgaa aggttaataa ggtaattatt ttgcaaaatt taaaaaaata
     2761 tcttttatta gatagcggtt tagtagttgg gtatacatta gaaaatgctc aattaaaatt
     2821 aaataagcta aaaaaagata ctgaaaacaa tccactattt ggtgaagagt attttgccga
     2881 aaatcctaaa ttatgggaag ttcgttttga taattcatat ccaaacgtta tctatgataa
     2941 agaattgaaa ttatatagat gttggtatca aacatttgtt agtgatgaag caagcgaaga
     3001 gactccttta gcagaacgtg gagagaagga atacattgtc aagtcatcta gaatgacagc
     3061 actttgctat gctgaaagta aagatggagt aaaatgggaa aaaccaaatc tcaatctagt
     3121 aaaatttaaa ggttcaaaag ataataatat tgttctgatg catgcacacg gtgcaggtat
     3181 catgctagat gaacaggagt tggatcctaa gaaacgatat aaattagttt caaaattaga
     3241 attttctccg aatcttcatt acatggttgt tgttttttca gaagacggta ttcattttga
     3301 cgaacctatt ccatggaaaa aatggaatcc tgcagcagat agtcataatt ttccatttag
     3361 agatccaaaa actggtaaat acgctgttat tacaagaacc tgggcaaata acgtacgtct
     3421 aagtgcaatt actttcagtg atgattttat taattggtca gaacctaaag aaatccttag
     3481 gggagatgga tttgaagatc aaatttattc tatgccagta atttcatacg cggatatcta
     3541 tttaggtttt gcttcaatgt accatgaagg cgacacttta aatgaaaact atgataaagt
     3601 agacttagaa ttgaaattct ctgctaattt ggaacaatgg gatagtgtat gtaagggcga
     3661 ctatctcatt gaaaggggag gtggagtata cccgcagaat gctgattttg atgctagttg
     3721 tattttcacg gctgctccaa taattgaaga tgataagatt tggttctact atatgggtgg
     3781 aaatggtaat cacactggct tccgagaaag ttcattagct agaggatata ttaagaaaga
     3841 ccaatttgct tattatacta ataagagaga aggaattcca gctaaaatat ctacagttag
     3901 cttccaaact tacgatgatg aaatttatat cttagctgat attcctgaaa atggttatat
     3961 taaagttgcg gtaggtacta aatacggtaa tgcttattca gatttcggtc aggaagatat
     4021 ctctcttgtt caagtttccg atggtaagta taagttggaa tttaataaaa aatctatctt
     4081 agatttaggt aattctccag ttgcgttcaa atttgaaatc gagaatgcaa aattgtatgg
     4141 tattgaaggt agtattcagc aacactatct caaatattaa ccagaataat tcgttaacaa
     4201 ataatctcta tattagtgga gatagatata taaaatggag gtcttattat ggtaaagctt
     4261 aataaggtat taaaagggag tgttgcattc ctgagtgcaa gtttattgct agcagcttgt
     4321 ggcaataacg ctaattcaaa gcccgctgaa aaaacagctg atggtaaaac gaaaatttcg
     4381 tttctatcta catggcaaat taatgatgtt cgtccgccta aagatgaaac acttgttggt
     4441 caatggttag aagaacagct aggtattgat attgatcttg taactattcc tggcgaggga
     4501 gtaagttcta aagtaaattc tcttattact agtaaccagt taccgactgt tttgttgaca
     4561 acaggagata agagtgatat cgctggtatc aacaaacttg gtaaacaggg tgcattctta
     4621 gatttgtcac aacacatgga caaactacca aactataaga agtaccttga aaaaaataat
     4681 gcattagctc aaatagaaga tgatgaaaaa catatttatg ctttcacaaa attctttact
     4741 gatgagaata tcatgtatac tacaccaatt ctgagaaaag acttacttgt tggttcagaa
     4801 tttgaagatc tttcaaaaat taaaactgtt gatgactata caaaagtttt gaaatatttg
     4861 actgaaaaac aaggttctcc agcatttatt caacgtaatg gctatgaagg cttcatgaag
     4921 cgagttacac cattgtggaa tttaagccat cgtacatact atgactatga atcagattca
     4981 tataaacatc cagttgaaca acctcaattg aaacaattcg ttgaatggtt gaaagaatta
     5041 cgtaaagata acgtacttca ccctgactgg gcagttatga aagatgaaac ttgggaaggt
     5101 ctattggctt ctaacaaggg ttcattcact gttgaccgta tgaatatcat tggagataat
     5161 aactttgata aatcatttga ttggcagcca cttgtttatc cagaaattaa tggaaaacgt
     5221 tatttgcaac cgaaaacacc gtacatttct gattcaggtt gggtaatcaa tgccaatgca
     5281 ccaaaagaag aaattgataa agcgttagaa ttctttaatt tcttatacgc tgatgaaaat
     5341 caagaaaaac ttgctattgg atttgaaggt aaaacattta cacgtgaaaa ccctaatact
     5401 caagcaggta ttaaatggtt gattcaaatt tacggtgaaa atgctggaaa tgataaagca
     5461 gaactgctgt ttaaacatgg taaccaagca tttactcgcg ttcaaactaa attagatatt
     5521 gaggcacagc caggaacatt ccctaaagtt atgtatgatc aagtagataa aattaagaaa
     5581 gatttaggtg gttttagacc agatactccg gttctttcct ttacaactga agaattagat
     5641 gttttaacta aatctgaagc aggattaaat actttctttg atgaaaatat tattaaattc
     5701 attgaaggac aaagagatat gagtgagtgg gattcattta tcaatgaagc taaatctaaa
     5761 gacttggata aagttacaaa agtatataat gatgcctaca aacgtgtcaa agatagaatg
     5821 aaatagacta aatggtagct ctctggtttt tcagagagct actactgcct gagggggagt
     5881 aagctttgta tgatgtagta attataggtg caggaagttc gggcgcattg gctgcaattg
     5941 cttcggggcg tctagggtta aaaacttgtc taatagagaa gggaagtaga attggtggag
     6001 ttcctattaa tacactaatg gggtcatttg ctaatctata ttttgatgat tctggtagag
     6061 taaatgcaag taaaattgtt ggggaattaa tagaacgtat tatcaaaaaa ggtggtactg
     6121 tctttaactc tatggaagaa ttgatgaatg taaatgattt ttatcagatt acaattccct
     6181 atcaaccaga agtttatgaa tcggttttaa ctgatatgtt gattgagtct aaagttgata
     6241 ttttactaaa tgttgaagtt aataatatta tttatgatag taaaaatatt aaaagtcttg
     6301 aaattttaag taatcaggaa gttaaattga ttgattctaa agtttttatt gatgctacag
     6361 ggaatgcaac aattgcttct gctagtggag ctgatgttta tgaaaaaaat tcttcttacg
     6421 gttgtttaat gagagttgga ggagttgata tctcaaagac tatagaacat attgaaaaaa
     6481 caaagcagtg gaactatata gaaggatata atcagtggtt agaagaagta ttagcaaatc
     6541 gaaagtacag agccactgga gcagttttaa aagatccagt ttcttatgat catgccccta
     6601 tgctttcaaa agacgaccat tttatgaatg atgaaaaatg gaattacatt aaagaaagat
     6661 gggaaaaatt tagatttatt tacactttag aagtatcact atttaggaat gaattaaaaa
     6721 aagctgtaga atctggggat tttaattttg aaatttatca tgatgataaa tctggagtca
     6781 ctatgaatgg cgacggtata agctatggtt catggggtca aaatgtagca ttaattaatg
     6841 ttgcaaaagc atttggattc aatcccaaat atatggaaga tgaatcacat gctaatattc
     6901 tttctagaaa atataattta acatttttat cttttcttaa aaaatatgta ccaggttttg
     6961 aaaattcttt tatccttgat cagggaacta gagctactaa cagatcatgt aggcacattg
     7021 ataattcatc tatgatggac gaaattcttg attttccaat gtatacattt aagactatgt
     7081 atagctatca aactcctaaa gaaataacgt acaaatcaat tgtaggtgga aaattgaata
     7141 atttgtttgt aataggtaaa ggtgcttacc aatccgaaag ttttagatca caaattagtt
     7201 gtatgttaat ggggatatca tcagcagcag cggcaaaaac tattattgaa gataaaagca
     7261 atactctaaa cattaataga gatttgttta aatcgaactt agatatatta tttacatggg
     7321 agttttctaa ttggattact gattaacaaa taataaggga atattaaatg aatgatacta
     7381 ataaaaatca atactttgtt tatgaatttg atactagctt tgtagaaatg tcttattctc
     7441 agttttttga aggatattgt attctttttt caaaagaacc ctatccttct ttatctgata
     7501 tgccaatgga atttagaaaa gaatttttaa tggaaatgag tatattaggt gatgcgatgc
     7561 ttgaagtgtt aaatgcctat agaattaatt atgatatctt aggaaattca acacctgtac
     7621 ttcatgctca tttatttccg agatacatgt gggaagagga agagagaaga aaaactgtag
     7681 ttcatagata tgattcttca gtttttagca atcctgagtt tgaatttact atagaaaagc
     7741 atggaccaat tattaaaaaa ctgaggtctg ctattgatag acattataga gagtatcaac
     7801 aattattaga tgattcaaac tgaactccac attttcgatt agatttaata ccttgtatat
     7861 tacaactagg ttgtggatga tataattttt tgaaaaatat attttaggaa tgacttataa
     7921 agcaattata tcagaggcta ttaaatcaat ggccaaagct tatgctcctt attctgattt
     7981 taaggttgga gctgcgttag taactgaaga taaaaaattt tttctggatg taatatagaa
     8041 aatgctgctt tttctcctac ttgctgtgca gaacgagtat ctttttataa agctgtattt
     8101 aaaggagaac gttcgttttc aagaacatgt attgtaggtg gaaaaaatgg tatcttatca
     8161 tcttttatag caccttgcgg agtgtgtcgc caggtaatga tagaatttgt aatcctgatt
     8221 catttgaagt tatattggct agtgatgttg atacttataa agtatataaa cttaaagaac
     8281 tactaccagt tagttttaat caagaaaatt tataacagga gggaactatg gaattagttg
     8341 aatttaaaaa tggacatgtt aatacggttc atgagcatat cgcaataacg aaagtaaaag
     8401 agtttctaaa taatcatgat atattaaaag ataaaggtgg catacataaa atttctactg
     8461 atttctttta caatataatt gatatggaaa ctacaactga agagaataga ccgtgggaaa
     8521 gtcataagga atattatgat gtccattatc tgttaaatgg agaagaaaca attttatata
     8581 acttcttgtc tcaaatggaa ttgtctgaat ataaagtaga tgatgattgg caacaaatga
     8641 atgggacagc tttatttagt attaaattaa agaaagatat gttacttttg ttggaaccaa
     8701 acgatgcaca tagaacaggc ctattggttg aagaaccact taatattaag aaagttgttt
     8761 ttaaggtaaa aatttaactg aaagtacttt cggggattaa gaattttaaa atatttaaga
     8821 aattgtattc taaagttcta aaattataga tatttaattt aaagcttgtt aaaatagaat
     8881 agtaacactc atctgctttc aaaaagcatt ctattccatc tccgattaac gatggacttt
     8941 atcacctcct tctccagtcc ttgtatgaca tcttggagtt gattcatgac atcttccaaa
     9001 gttcgaaagg ctttattctt aaatccacgt ttatgaatct ctttccacac ttgttcgatg
     9061 ggttcatctc tggtgtgtat ggaggaataa atgcaaaacc aatattagtc ggagtcttta
     9121 agg
//
LOCUS       DAVBCA010000074         8962 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.074, whole genome shotgun sequence.
ACCESSION   DAVBCA010000074 DAVBCA010000000
VERSION     DAVBCA010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8962)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8962)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8962
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.074"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            264..1322
                     /locus_tag="VQU19_001888"
     CDS             264..1322
                     /locus_tag="VQU19_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2481089.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIESKGIFVSILMAVLLLYLI
                     YFIATVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREIALLLATIIVYFFTHRILPLSVFTFIFSYILLFAQ
                     SYLGGNTVWIGNRRLIIDDEFEKILLSKSYIKEISSARYSEYLTCEYKNLTPIILLAI
                     FENLLDSYLLQNQSEVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYD
                     NEALGDLSKQYLNRNISELQDGSFDGGIQDAVASKQIVVINEFIACLNSRCMPSQYDR
                     FFYKDRPYIFSRKSPIKG"
     gene            1637..2611
                     /locus_tag="VQU19_001889"
     CDS             1637..2611
                     /locus_tag="VQU19_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2481090.1"
                     /translation="MKNKRYFFDTILMILLLISTIFCVSPVFIKLDILGTPSHAILTF
                     VLAIPLFYILSQCLHTLLLLVSSIFCKLRPIYFYFIFVIIIGARKYYRILFHQLMGFS
                     PGIAVFYKESQTTKNLFKFYYFLYFTTLISYYFFFTFVYDKPLLLPLIPFSIIIALVQ
                     KLYRIENQQLFLLKSKVLTILESKKNCEFNLQDYHEIWKLQSKSELPCVALSYISLIK
                     PYLSESVREQIDLLEVKRFKKINHPISLYGMLDVIKLNLYLRHYNEKNKYESMLKKIL
                     EVRPDFVLIEQNIDDSLNSSQPLSLSLAISEIQLLLEVYMGIKHVSTK"
     gene            2991..3365
                     /locus_tag="VQU19_001890"
     CDS             2991..3365
                     /locus_tag="VQU19_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HET2481091.1"
                     /translation="MELVLPNNYVVLEQEEMMYLDGGFSIPRWPVATAINIAFNGVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAGFALSAINGFAAWMSIGD
                     AITTIWANNDVNRRDPNLNALW"
     gene            3573..4475
                     /locus_tag="VQU19_001891"
     CDS             3573..4475
                     /locus_tag="VQU19_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2481092.1"
                     /translation="MIRKLIVFLLMLPLFVLWLELHVLVNNLLLNLESPLDFVISMSL
                     AFCSLILSKIVLDILYALKDLYKKEGLIKIFPFIFIRRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWQKEDSFESNLHKILMDKIQKSELSYSDLMSLLLYDAMNQSTFLTDSELFEDILKKI
                     EDSHNTLLCTGLVELLLYEISISNNNNWQEKVDKIRIQLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            4531..4770
                     /locus_tag="VQU19_001892"
     CDS             4531..4770
                     /locus_tag="VQU19_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HET2481093.1"
                     /translation="MELVLPNNYVVIDEEVMMYLDGGAYLSKRACQGICAAAGVLATA
                     AGKIAYCIGYGVLNRGCDINENPYPWDGFISATVR"
     gene            4767..5495
                     /locus_tag="VQU19_001893"
     CDS             4767..5495
                     /locus_tag="VQU19_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2481094.1"
                     /translation="MSNVDKIRKIHIIVCWVYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLVINSILLMSFPILINKFFPESFLTYTVLISVFILELAIFHL
                     IRKDFDIKLTNEYKKISQFRSKVSQSPWIKYLEISSFILTIFPSILYGKVDNHVLTLI
                     FLIKICVDTTIKFLFIRLFDTSTLMKRRIFFLFALDVIAYLFLGYLLVIQKAGYLFSV
                     LLLFSNFSVPFIKEKEYELFKNSK"
     gene            6630..6869
                     /locus_tag="VQU19_001894"
     CDS             6630..6869
                     /locus_tag="VQU19_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2481095.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLEIFKVNFCLTDLHHLF
                     DLYKITRDYASQTKPAIQDGVFILEDFRNILCTMM"
     gene            7419..>8962
                     /locus_tag="VQU19_001895"
     CDS             7419..>8962
                     /locus_tag="VQU19_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein"
                     /protein_id="HET2481096.1"
                     /translation="MNKKKMILTSLASVAILGAGFVTSQPTFVRAEEAPVASQSKAEK
                     DYDAAVKKYEAAKKEYEDGKAAQKKYEDDQKKTEEKAEEERKASEEEQAANLKYQQEL
                     VKYIRENDPTKKAEAKKAMDEAEKEYKKKQTEFAEVRAKVIPSAEELKKTRQKAEEAK
                     AKEAELTKKVEEAEKKVTEAKQKVDAEHAEEVAPQAKIAELEHEVQKLEKALKEIDES
                     DSEDYVKEGLRAPLQFELDVKQAKLSKLEELSDKIDELDAEIAKLEKDVEDFKNSDGE
                     QAGQYLAAAEEDLVAKKAELEKTEADLKKAVNEPEKPAEETPAPAPKPEQPAEQPKPA
                     PAPQPEKPAEEPENPAPAPQPEKSADQQAEEDYARRSEEEYNRLTQQQPPKAEKPAPA
                     PQPGWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNANGAMATGWLQYNGSWYYLNAN
                     GAMATGWLQYNDSWYYLNANGAMATGWLQYNGSWYYLNANGAMATGWAKVNGSWYYLN
                     ANGSMAT"
BASE COUNT         3080 a         1249 c         1648 g         2985 t
ORIGIN      
        1 taaatctaat aaattctatt attatagctc ttggtatgat attggcatta attttggtat
       61 tatcaagagt gtatagaaaa tatttttata gagacgatga tgactaaagt ttttatcaat
      121 aatttgggct ccttgtcaac tgtagtggat tgaagaaaag ctaacgtctg gggaagggtt
      181 taaagctttg ctttatcaaa tattgactta cagagttgct ctattgtatt gatgtattct
      241 tagtaaataa tatggtgttt tgaatgaaag atgatcagaa atatttatta gcgggacttt
      301 attcgcttct agttgcaata ttttattttc cattgattga gtccaagggg atttttgtaa
      361 gtatattgat ggcggtttta cttttatatt taatatactt cattgcaaca gtcattcata
      421 ttgtgataat taagtttata agaaaaaaat cttttaagta tttggttcta tatccattta
      481 cttatgatgg gagctggaga tttcaaccta taaacttact ctactttcca gaaatggtga
      541 gagatgtcat tccgattaat ttagttcaag aatattgcca aggacaacct tacggactgt
      601 taaaaaagat gctgaaaaga attcgattgt cacgagagat agctttactc ctggctacca
      661 ttatcgtcta tttttttacg catagaattc tacctctttc agtatttacg ttcatatttt
      721 cttacatatt gctatttgca caatcttatt tgggtggtaa taccgtttgg attggaaata
      781 gaagattaat aatagatgat gaatttgaaa aaatcttgct ttcaaaaagt tatataaaag
      841 aaatatcatc tgcacgatac tcggaatact tgacatgtga atacaaaaac cttacaccaa
      901 tcatattgtt agctattttt gaaaatttgc ttgactccta cttgcttcag aatcagagtg
      961 aggttgactt agatattttt tataaagttt tacctttgct ttataaagaa aaatatacta
     1021 tgggattcaa ttactttgta agtttaaatt atttactata taaggttgga tttttgggaa
     1081 tcatttacga taatgaagca ttaggagatt tgtcaaaaca atatttaaac agaaatattt
     1141 cggaattaca agatggttct ttcgatggcg gtatacaaga tgctgttgcc tctaaacaaa
     1201 tagtagttat aaatgaattt atagcttgtt taaattccag atgcatgcca tcccaatatg
     1261 atagattttt ttataaagat agaccttata ttttttccag aaagagtcct attaaggggt
     1321 gaaaatttgt tacatttgga ttaacaagtg tcctagggat tagaaataac tctagtatag
     1381 ctagatattt ttgagtaact agaaatatca ttaggctacc catatgattg ccagaaaaga
     1441 tggctgatga atcttattta tactgttgca gtaggcattg tctaggataa ataagctatc
     1501 ttgatggggg aaattggaat aattttagta gaaacattaa aggattatgg acaagtagcg
     1561 caggattagg tgatgcaatg tgctaagttg gcttggtgtt agcagtagta ttatttaaca
     1621 atggaaagta gactaaatga aaaataagcg ttattttttt gacacaattt taatgatttt
     1681 actgcttata agcacgatat tttgtgtcag cccagtattt ataaaattgg acatcttagg
     1741 aaccccctct catgccatct taacctttgt attggcgata ccgttattct atattttgtc
     1801 tcaatgctta catactttgc tattactagt ttcctcaatc ttttgtaaat taagaccaat
     1861 ttatttttat tttatatttg tgatcattat aggagctagg aaatactatc gaattctctt
     1921 tcaccaacta atgggattta gtccaggaat agcagtgttt tataaggaga gtcaaacaac
     1981 taagaatctg tttaaatttt actacttctt gtactttaca acactaattt catactattt
     2041 tttctttact tttgtgtatg acaaaccgtt gcttttgcct cttattccat tttctattat
     2101 catagcatta gtacaaaaac tttatagaat tgagaatcaa caattatttc tgttaaaatc
     2161 aaaggtacta acaatactgg aatctaagaa gaattgtgag tttaatcttc aggattatca
     2221 tgaaatttgg aaattgcaat caaaatctga gttgccatgc gtggctttat cttatatcag
     2281 tttgatcaag ccatatcttt cagagagcgt gcgtgaacaa attgatttat tagaagttaa
     2341 gcgatttaaa aaaataaatc atccaatatc actttatggt atgttggatg ttataaaatt
     2401 aaatctatat ttacggcatt ataatgaaaa aaataaatat gaatcaatgt taaagaaaat
     2461 tttagaggta agaccagact ttgttttaat cgagcagaat attgatgata gtttaaatag
     2521 ctcgcaacca ttatctttat ctttagccat ttcagaaatc caacttttgc ttgaagtgta
     2581 tatggggatc aaacatgttt caaccaagtg ataaaaccag aataatattt gccattatag
     2641 gggcaagttg catattagtc agtatgtatc ttattccact tattaaaact gagaataaat
     2701 tttgggaaat acttttattt atattaggtg tattgctaat tggaattgcg ttactaagtc
     2761 aaaaaaaata aattttgaaa tagtattagt gagttcgcaa tcatttattg ctagtggttt
     2821 agaactgtta agtttcaaac aataattgat tttaaacctt aggtaaccta taaaaacaaa
     2881 taaggtagag aaaggatatc ttatctaggt agctaagtga taaaaacaca gtcgtctatc
     2941 acttgttagg aaactatcct aactatgctt aataaaaaag gagaaaataa atggaactcg
     3001 tattaccaaa taattatgtt gttcttgagc aagaagagat gatgtatctt gatgggggat
     3061 tttctattcc gagatggcct gttgcaacag ccattaatat agcttttaat ggtgttttag
     3121 gtggaggagc aatcagtcta gttagaaatt atattcgtaa ttatggtttg cggcgagtta
     3181 caagcgcaat tgctggagca gctgcaagat atgttggggt acgagttgca aatagagtgg
     3241 caggatttgc actgtctgct attaatggat ttgcagcttg gatgtcaatt ggcgatgcta
     3301 ttacaacaat ctgggccaac aatgatgtaa ataggagaga cccaaattta aacgccttgt
     3361 ggtaactaga tatgggtatt aaaatggaaa aaatttttgt tattattttt tttgtatgtc
     3421 tatttatatc atccataact tttttagcct atgattttgt tagcgaagaa ataaaaaagt
     3481 tgattatttg gattaatgtc gtttttttga ttttaatcat agcaatgatg atttatccaa
     3541 aattaagaaa atgataagga cactgtaaaa ttatgatacg taaactaatt gttttcttac
     3601 taatgctccc tctttttgtc ttgtggctag agttgcatgt cctagtgaat aacttactat
     3661 tgaatctaga atctcccctt gattttgtga ttagtatgag tcttgctttc tgtagtttga
     3721 ttttatcaaa aatagtttta gacatactat acgcattgaa agatttatac aagaaagaag
     3781 gtcttattaa gatttttccc tttattttta taagaaggaa aaaagtgaat gtgagattct
     3841 cgccctattt ttcattccat cgtaaaagtt tgtcgcctga tgatttaaga tctaggatta
     3901 tatggagttt tattcttgaa attgctatta tcctagtatt tattttaaaa attccttttg
     3961 caatcatcat gcttactaca atatttttct ggactataat ggatatcaat catctcgttt
     4021 ttaataagac ggaatttctt tttaatcaaa acaaatggca aaaagaagat tcatttgaaa
     4081 gtaatttgca taagatattg atggacaaaa tacaaaaatc agaattaagc tattctgact
     4141 taatgtccct tcttctctat gatgcgatga accaatccac ctttttaacg gatagtgaac
     4201 tttttgagga tattttgaaa aaaatcgaag attctcataa cacccttctg tgtacaggtc
     4261 ttgtcgagtt actgctgtat gagatttcta ttagtaacaa taacaactgg caagaaaagg
     4321 ttgataaaat tagaatacag ctcatcagaa tcaatcaatt agattttttc tattatacaa
     4381 gttggttaag gcaaaatttt gatttctgta tgaatagaga gtatcataaa atgaaatctc
     4441 ggaaattatt actgagtaat aaaaagatag tttaagttcg tcctatttgt aaaacaaatg
     4501 aaacaatttc aactaaggag gagaaaacaa atggaacttg tattaccaaa taattatgtt
     4561 gtgattgatg aagaagtaat gatgtatctt gatgggggag cttatttaag caagcgtgct
     4621 tgtcaaggaa tttgcgcagc agcaggtgta ttggctacag cagcagggaa aatagcttac
     4681 tgtattggat atggtgttct taatagaggt tgtgatatta acgagaaccc ttatccttgg
     4741 gatggattca tatctgcaac agtaagatga gtaatgtaga taagattcga aaaatacaca
     4801 tcatcgtgtg ttgggtgtat atatttttat cattcagggc gattataaat gatacggagt
     4861 attttttgct tattttttta gcttttatct actcaatagt atcactacct ctatattctg
     4921 tgaaaaataa aatagtatct atctgtctag ttataaattc gattctgtta atgagtttcc
     4981 ccattttaat caataagttt ttcccagaaa gttttttgac ttataccgta ttaataagtg
     5041 tttttatcct agagttagca atctttcatt taattaggaa agattttgat attaaattga
     5101 ctaacgaata taagaaaatt agtcagttta gaagcaaggt gtctcaatct ccttggataa
     5161 aatatttaga gatttctagt tttatattaa ctatatttcc atctattctt tatggtaaag
     5221 ttgataatca tgtactgact cttatctttt tgataaaaat ttgtgtagat actacgataa
     5281 aatttttatt catcagatta tttgacacaa gtactttaat gaagaggaga atattttttc
     5341 ttttcgcatt ggatgttata gcttacttat ttttaggata tcttttagtg attcaaaaag
     5401 caggctattt gttttcggtt ttacttcttt tttctaattt ttcagttcca tttatcaaag
     5461 aaaaggaata cgaattattt aaaaatagca agtaatagaa atatggatta aatcttagaa
     5521 cggcttaaaa tcagatatga taaagggaaa tagtcttatc taggtaacta agtgctacaa
     5581 acacaatcga ggatcacttg ttaggattac attttaatca tgcttaataa gaatggagaa
     5641 ttcctatggg gattgtatta ctctgaagtt tcgaatacct tagttctcgt gattttgagc
     5701 tattctagct ttagaatcct tcagaacgta aaattttaag cagtcaaaga cttagaatag
     5761 cctgaaaaca tttattttat agcaattcta ggcttagaat tgctcatata tatgtatttg
     5821 agctgctcga tagttaggac agctctattc tgagaaatct gagctatcaa tgcttcagaa
     5881 tagtatttcg ccaatggttt ttattgaaga ggtgattgtg ttatgatagt ctaaaataaa
     5941 attgatttaa tagagtaaat ggagaatcgt tacatgaaac atttttttgc aggaattggt
     6001 gagataaaac ttgttggcta cttattgtat atatgtgtag gactagcccc tctttttcat
     6061 atatatgtca taggttcgga actgagtttt gtgaaaatag tgttatctat tttgggagtt
     6121 atatttgtaa gtatgttaac tattgctcga atttatcgga cttttctata aagaatagtt
     6181 tggacttaaa ctgtatctaa aaacagaggt tggtcgatta tcagcctctt tcttgtcgtt
     6241 gaaaagagtg agatatattg acttttgaaa aaaagatgtc ataattgagt tgggataaac
     6301 ctaaaagtaa tatagtagat tgaatctgga atagtccgtt atgactgtta aaatatttct
     6361 agaaattaat ttgactttcc taatcgattt gttcacatct tgtttcaatc tactatactt
     6421 tctcgttaaa ccgttcggca attcatggtg acatggacac atagtagtaa gcacactatg
     6481 tggcttggca gagctaaaaa ctgttccctt gcgataagcc taataagcac aacataggga
     6541 gttagagaag ccgactctaa tcaaccactt tgggcaatag tgagaactgc cccgtgcttt
     6601 tttattttga gaaaatatgg agtttgtcgt tgaaattact tgattgtatt ttggactatc
     6661 aagaaagatt caatggaaaa acatgtcaag tatcaacgaa ttataagtat ttagagattt
     6721 tcaaagtgaa tttttgtttg actgatttac atcatttatt tgacttatac aaaatcacac
     6781 gagattatgc tagtcaaaca aaacctgcta ttcaagatgg tgtttttatt ttagaagatt
     6841 ttagaaatat cctatgtaca atgatgtaat cgaaaggata tctttatgtg agtttatcgg
     6901 cgatatcttc tatatctaag ctagcaagtt gttgcatcgt agctaaggat ttatctaaaa
     6961 atactatgaa attggacgtc atattttttg aggataaaaa taaaagatcc gcagttttag
     7021 gtttacgaag agacaaaagc ggagtattta aaccagttac tctacatttt acaagcgcta
     7081 agaaatatgc taaagttcgt aaaacagatg tgaaagaaat gaaatggcta taaagattgt
     7141 ccgcaggctt aagcttgcgt tttttgttgt ttaacgaaat taaaaaacaa gctctctcat
     7201 cggaaatgtt tttataggaa tgaaggaaga tgatgctatg tttaaaaaga gaatcgaaaa
     7261 gggcaaaagt agtgtcttta tctttttgga gtagaagctt atgatataga aatttgtaat
     7321 aaaaatgtaa tataaaacat ttgacaaata tttacggggg gagtatactt aatataagta
     7381 tagtctaaaa atgactatca gaaaagaggt aaatttagat gaataagaaa aaaatgattt
     7441 taacaagtct agccagcgtc gctatcttag gggctggttt tgttacgtct caacctactt
     7501 ttgtaagagc agaagaagct cccgtagcta gtcagtctaa agctgagaaa gactatgatg
     7561 cagcagtgaa aaaatatgaa gctgctaaga aggaatatga ggacggaaaa gctgctcaga
     7621 aaaagtatga agatgatcag aagaaaactg aggagaaagc ggaagaagaa agaaaagctt
     7681 ctgaagaaga acaagctgca aatctgaaat atcaacaaga gttggttaaa tatatacgtg
     7741 aaaatgatcc aacaaaaaaa gctgaagcta agaaagcaat ggatgaggct gagaaagagt
     7801 ataagaaaaa acaaacggaa tttgctgaag ttcgtgcaaa ggtaattcct agcgcggaag
     7861 aattaaaaaa gactagacaa aaagcagaag aggctaaagc aaaagaagca gaacttacta
     7921 aaaaagtaga agaagctgag aaaaaagtta ctgaagccaa acaaaaagtg gatgcagaac
     7981 atgctgaaga agtcgctcct caagctaaaa tcgctgaatt ggaacatgaa gttcagaaac
     8041 tagaaaaagc tctcaaagag attgatgagt ctgattcaga agattatgtt aaagaaggtc
     8101 tccgtgctcc tcttcaattt gaattggatg ttaagcaagc taaactatca aaacttgaag
     8161 agttgagtga taagattgat gagttagacg ctgaaattgc aaaacttgaa aaagatgtag
     8221 aagatttcaa aaactcagac ggtgagcaag ctggacaata ccttgctgca gctgaagaag
     8281 acttagttgc taaaaaagct gaattagaaa aaactgaagc tgaccttaag aaagcagtta
     8341 atgagccaga aaaaccagct gaagaaactc cagctccagc accaaaacca gagcaaccag
     8401 ctgaacaacc aaaaccagcg ccggctcctc aaccagaaaa accagctgaa gagcctgaga
     8461 atccagctcc agcaccacaa ccagagaagt cagcagatca acaagctgaa gaagactatg
     8521 ctcgtagatc agaagaagaa tataatcgct tgacccaaca gcaaccgcca aaagcagaaa
     8581 aaccagctcc tgcaccacaa ccaggttgga aacaagaaaa cggtatgtgg tacttctaca
     8641 atactgatgg ttcaatggct acaggttggc tacaaaacaa cggttcatgg tactacctca
     8701 acgctaatgg tgctatggct acaggttggc tccaatacaa cggttcatgg tactacctca
     8761 acgctaatgg tgctatggct acaggttggc tccaatacaa cgattcatgg tattacctaa
     8821 acgctaacgg cgctatggct acaggttggc tccaatacaa cggttcatgg tactacctca
     8881 acgctaacgg tgctatggct acaggttggg ctaaagtcaa cggttcatgg tactacctca
     8941 acgctaacgg ttcaatggca ac
//
LOCUS       DAVBCA010000075         8848 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.075, whole genome shotgun sequence.
ACCESSION   DAVBCA010000075 DAVBCA010000000
VERSION     DAVBCA010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8848)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8848)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8848
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.075"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(185..1153)
                     /locus_tag="VQU19_001896"
     CDS             complement(185..1153)
                     /locus_tag="VQU19_001896"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HET2481097.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(1298..2113)
                     /locus_tag="VQU19_001897"
     CDS             complement(1298..2113)
                     /locus_tag="VQU19_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HET2481098.1"
                     /translation="MKKSSILFIFILLLCIGLQYETIYYTDGSRSGAEYGLMGVSIFL
                     ALFYMIPALYFLFRIGKKWELPKKVLILSLLGGMFLSGWLSSFTNTYIHDLLGVLFPD
                     SPFLNAFESAIVAPLVEEPLKLLPLVFVLALIPVRKLKSLFLLGIASGLGFQMIEDIG
                     YIRTDLPEGFDFTISRILERIISGIASHWTFSGLAVVGVYLLYRAHKEQKVGKKQGLI
                     FLGLALRTHFLFNSPFVELETELPLAIPVVTAIALYGFYHAYCFVEKHNELMT"
     gene            complement(2138..2635)
                     /locus_tag="VQU19_001898"
     CDS             complement(2138..2635)
                     /locus_tag="VQU19_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HET2481099.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            complement(2708..4069)
                     /gene="radA"
                     /locus_tag="VQU19_001899"
     CDS             complement(2708..4069)
                     /gene="radA"
                     /locus_tag="VQU19_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HET2481100.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MSVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            complement(4083..4598)
                     /locus_tag="VQU19_001900"
     CDS             complement(4083..4598)
                     /locus_tag="VQU19_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET2481101.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGFPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            complement(4600..5043)
                     /locus_tag="VQU19_001901"
     CDS             complement(4600..5043)
                     /locus_tag="VQU19_001901"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HET2481102.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            complement(5100..5197)
                     /gene="ffs"
                     /locus_tag="VQU19_001902"
     ncRNA           complement(5100..5197)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VQU19_001902"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(5230..5697)
                     /locus_tag="VQU19_001903"
     CDS             complement(5230..5697)
                     /locus_tag="VQU19_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HET2481103.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYDILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            complement(5898..7184)
                     /locus_tag="VQU19_001904"
     CDS             complement(5898..7184)
                     /locus_tag="VQU19_001904"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HET2481104.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGIGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGARNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(7415..7651)
                     /locus_tag="VQU19_001905"
     CDS             complement(7415..7651)
                     /locus_tag="VQU19_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HET2481105.1"
                     /translation="MLQKIYEQMTNFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            7917..8714
                     /locus_tag="VQU19_001906"
                     /pseudo
     CDS             7917..8714
                     /locus_tag="VQU19_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(8749..>8848)
                     /locus_tag="VQU19_001907"
     CDS             complement(8749..>8848)
                     /locus_tag="VQU19_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HET2481106.1"
                     /translation="EKTWAYIKKNLKKVLPSCNTFYEALFSCSCFN"
BASE COUNT         2835 a         2112 c         1419 g         2482 t
ORIGIN      
        1 cgtcgattca agtgctatca ctgttcaaaa atgatggtcg ctgaaactta tgatgacgta
       61 cagtcatatt tcttctcttt ttattatatc acagttttaa atctagcttt actagattca
      121 ccgctactat ctatttattc ggaaaaaaga cgaaaaaacc tgagaatcat ctcaggcttg
      181 gtcattaaat ttttttctca atatcgaaaa gtggagaaag tggtcgtttt tcatgaatac
      241 gtacgatagc atcccctagg agatgagcga ttgaaatctg ctcaatctta tcaatcaaac
      301 gctcttctgg cagatagatg gtatccaaaa caaccaattt cttaatagct gatttttgga
      361 tattgtccgt agcaggacca gaaagaactg ggtgcgtaca gcttgcatag acttcaacag
      421 caccagcttc cgcaagagca tctgccgcat gacaaatcgt tccagcggta tcaatcatat
      481 catcaatcaa gatacaagtc ttgccttcaa ccttaccgat gatgttcata acttcactag
      541 tattcatctt atcaacgcta cgacgtttat caataatagc gatagatgtt ttcaaaaatt
      601 ctgccaactt acgagcacga gtcacccctc catggtccgg gctgacaacc acatagtcag
      661 aaccaaccat accacgacgc tcaaaataat ctgcaatcag aggagcaccc atcaaatgat
      721 ccacaggaat atcaaagaat ccttgaattt gcgcagcatg caagtcgatg gtcaataaac
      781 gatccactcc agctacttca agcatatttg cgacaagttt tgaagtgatt ggctcacgcg
      841 ctctcgcctt tctatcctga cgtgcatacc catagtaagg catgacaaca ttgacagatt
      901 ctgcactcgc acgcttcaaa gcatctacca taatcaaaat ttcaagcaga ttgtcattta
      961 caggcgaact agttgattgt aggataaaga cgtgtttccc acggattgat tcttcaatgt
     1021 tgacctgaat ctctccatct gaaaattggc gaacacttga tttccccaac tctatcccaa
     1081 tctcctgcgc cacacgttct gccaattctt tattagaaga aagggcaaac agctttaaat
     1141 cagaaaaaga catgatttcc tccggtatat atgtatcgct tgtgcttttc acaagatttt
     1201 ccatctacca ttgtagcgct ttttgcacta tttttcaatc aaaaataaaa gaagggcacc
     1261 atatttgtac ccttgcatca ttcttttgaa aaatattcta ggtcatcaac tcattgtgtt
     1321 tctcaacaaa gcaataagca tgataaaaac catagagagc aatagccgta accactggaa
     1381 tcgctaaagg caactctgtt tccaactcca caaaaggaga gttaaacaag aagtgagttc
     1441 tcaaggctaa acctagaaaa ataaggccct gtttcttgcc aaccttctgt tctttatggg
     1501 ctctgtaaag caagtaaaca cctactacag ctagacctga aaaagtccag tgagaggcaa
     1561 ttcctgagat gatacgctct aaaattcgcg aaatagtaaa gtcaaagccc tctggcaaat
     1621 ccgtacgaat ataaccaata tcctcaatca tttggaatcc caaaccggaa gcaattccaa
     1681 gtaaaaacaa agattttaat tttcgcacag gaatcaaagc caaaacaaaa acaagtggca
     1741 ataatttcaa gggttcttct accaaaggag ccacaatagc actttcaaag gcatttaaaa
     1801 atggactatc tgggaaaaga acccccagta aatcatggat ataagtatta gtaaaactag
     1861 acaaccagcc tgaaaggaac atccctccca ataaagacag aatcaaaacc ttctttggca
     1921 attcccattt tttcccaata cggaagagaa aataaagagc cggaatcatg taaaagagag
     1981 ctagaaagat agaaactccc attagtccat attccgcacc tgacctcgaa ccgtccgtat
     2041 agtagatggt ttcatactgt aaaccaatac atagcaataa aataaaaata aataaaatac
     2101 tgcttttctt catacacttt ctttctaaat gaagtattta taattctacg actgtcatac
     2161 ttcctgtatc aacattgtaa atggcaccag agataatgac atcgtctggt attaggggag
     2221 actcgataag cagttgcata tcctcgcgta cactctcttc tatatcttgg aagggcaaga
     2281 agtcctggtc tgacacatct acacctaatt cctcttttaa atactcctga aaaggttcat
     2341 tttcaaaggt ctgagcacca cagtctgtat ggtgcaatac cacaatctct cttgtcccca
     2401 tttgttgctg ggaaataact agcgaacgaa tcatgtcttc agtcactcga ccacctgcat
     2461 tccgcaagat atgagcatcc ccaagtgcca agcccagagc ttgcgcaacg tgcagacgag
     2521 agtccataca ggtcacaata gctactcttg ttttgggttt aagtggcaga tttaactgcc
     2581 catgtagggc aacataagcc tgattagctt gcataaactg ttcaaaatac gacacgattc
     2641 cctccttgaa aatttgatag tcaaatattt ctcctatctt atcattttta agagaatttg
     2701 tcacggatta tgcaaagacc tttttcaaaa cttcctgaat cgttgtcacg ccaatgacct
     2761 gaatttcctt aggcagagtg attcctgtca aggaattctt aggtacataa atcttagtaa
     2821 agcccagttt agcagcttcg ttgatgcgtt gctcaatacg attcacgcgc cgaatctctc
     2881 ctgtcaagcc cagttctccg acaaaacatt cctgaggatt agttggcttg tctttgtagc
     2941 tcgaagcaat agcaactgca acagccaagt caatggcagg ttcatccaat ttaacaccac
     3001 cagcagattt gagataggca tcctgatttt gcaagagaag ccctgcccgt ttttccaaaa
     3061 cagacataat caagctagca cggttaaaat caagtcctgt cgtagtacgc ttggcatttc
     3121 caaacatggt cggtgttacc aaagcctgaa cctccgccaa aatcggacgc gtcccttcca
     3181 tggttacaac gatggaggaa ccagtcgccc catccaaacg ctcttctagg aaaacttgac
     3241 tcggattgag tacctcaacc aagccgcccg actgcatctc aaaaatccca atctcattag
     3301 tggaaccaaa acgatttttg accgctctca aaatacgaaa ggtgtggtga cgctcccctt
     3361 caaagtaaag caccgtatcc accatatgct ccaacatacg aggcccagcc aaggttcctt
     3421 ctttggtcac atgacctacg ataaagatgg caatgttatt ggtcttggcc aactgcatga
     3481 gttcagcggt cacttcacgc acctgagaaa cagacccctg cacccctgaa atctcaggag
     3541 acatgatggt ctggatggaa tcaataatga gaaagtctgg ctggatacgc tccacttctg
     3601 cacgaacact ctgcatattg gtctctgcat agagataaaa ctcactatca atatcaccta
     3661 agcgctctgc acgtagttta atctgctggg cagactcctc cccactgaca tagagaactg
     3721 tccccacttg ggacaactgg gttgagactt gtaggagaag agttgatttc ccaatcccag
     3781 gatccccacc gatgaggacg agacttcctg gtaccactcc gcctccaagc acacggttga
     3841 attcctccat ctccgtcttg gttcgattga cattgatgga agtcacctca gctagtttca
     3901 tgggcttggt tttctcacct gtcaaggaca cacgcgcatt cttgacctcg gcaacctcaa
     3961 cctcttccac aaaagaagac caagacccac agttggggca acgtcccaga tatttagggg
     4021 aattataccc acaattttga catacaaatg tcgctttttt ctttgcgatg acaaacctct
     4081 ttctatatct ctaactcaca ctcaatcact tggcaaaaat caatcttctc atttggcaca
     4141 aactggcgca tgagcattcg atgagcaaca actaccacag tctgatgttc tcgatactta
     4201 gacatacatt ctagaaaccg agacttcatt tccgtagctg tctcatattg aataggacta
     4261 ttaggaagca actccccctt gttttctaaa aacagtcttc tagctgtttc aaagttttct
     4321 attcctgttt tatagacctg ccattcatgt aataaaggct ctactcttaa aggaaaaccc
     4381 gtagcacata ccacatacga agccgtttct aaagctcttg tgactgcaga agatacgatt
     4441 atttcagctg acgagagtaa aggatttttg ctcaatttct ggacttgctg ccgtcccatc
     4501 tcagacaagg gtgccaaatc tatcccaaat cctatataag aacgctcctc taactcacgg
     4561 taatctggct ccccatgacg tacaaagata atcttcattc tagtgccctg tcgatccaaa
     4621 tccaccagtt cgaacgccat cagccgcatc tccatctgca attaagaaag tagcaaaaac
     4681 agcctggaca atacgctccc caacttcaag aacaacctct tggtctgtga tattcttcat
     4741 ctgcgcaaaa atatgccctt catttccagg atttccataa taatccccat caatgactcc
     4801 aactgagtta attaaaacca agcccttctt acgaggattt gaagaacgat catagaggta
     4861 gagaacctca gtcggctgca tataagcctt aacccctgtc ggaaccaaga caatctctcc
     4921 tggcgcaaca actgtacgca cagcaacctt taagtcgtaa ccagccgcat gcgctgtctc
     4981 acgcttgggc aataaatttt catctgtaaa actcgaaacc aattcaaaac cacgaatttt
     5041 cataattttc tcttttctat tatcatttat tctagattat tctatcttat ttattcggaa
     5101 aaagcacgaa aaaaagagca cacaattcaa atcgcttagg gctgctggat tcctcccctg
     5161 acccgcttca cgcagaactg ttgctccact atttattata tcacattcct attcatttta
     5221 aaagcaaaat tattttttcc gtctatttct aaaaaaatcc tgcatgatag ctgcgcattc
     5281 atcttccaaa attcctattt caacctccac acgatgatta agacgctcat ctgtcaagat
     5341 atcgtacaaa cttccagcag cgccaaattt ctggttttta gccccataga ccacatttgg
     5401 aatgcgggca agcccaatcg ccccactaca catgacacaa ggttcaatgg tcacaaaaag
     5461 tgtgcaatcc agcaagcgcc agctctcctc actcaagttc gcatcctcta tagccataat
     5521 ttccgcatgc ataaccgctc gctgtaattc ctcacgcgca ttatgcccac gaccaatgat
     5581 ttccccatct ttgacaatca cacaaccaat tggaatttca tcgtgttcaa gagcaatctc
     5641 agcctctctc aaagcctccc tcataaagac ttctttttct tcaagcgtat aatacatctc
     5701 ttttctcttt tcctacttat cgattttatt attatatcat gaatcccaac acaaaaaaag
     5761 ccaccgaatg cggtgactct atagggagat tattatgaaa aagaaaagtt taggatattt
     5821 gttacaacaa gttaggaggt cttcttgtaa ctgtctatag tatacccgac ctatcttaaa
     5881 caaatcttaa aaatctctta ggaccaaaca ctttctaaaa tatttgtttg ttcacgacca
     5941 ggacctactg agaaagtaga aatacgaacg ccaaccaatt cactcacacg acgaacatag
     6001 ttacgcgcat tctcaggaag atcttccaaa ttgcgagctc cggtaatatc ttctgaccaa
     6061 cctggcaact cttcatagat aggcttgcaa cgtttcaatt gctcaagact agctggatag
     6121 tagtcaatac gttgaccgtc aagatcatag gccacacaaa ttttcacagt atccaagccg
     6181 ctcaaaacat caatagagtt caaagaaagg ttagtaatac cagaaacacg acggctatga
     6241 cgcatcacaa ctgagtcaaa ccaacctaca cgacgtggac gaccagttgt tgtaccatat
     6301 tcatgaccca cttcacggat acgttctccc acttcatcaa acaactcagt tgggaaagga
     6361 ccatctccta cacgactcgt ataagcttta catacaccta caaccttgtc aatcttgctt
     6421 ggaccgatac cagaaccaat tgtcacacca ccagctacag ggtttgatga cgtaacaaat
     6481 ggataagtac cttgatcgat atctagcata acaccttgtg caccttcaaa aagcacacgt
     6541 ttgccattat caagcgcatc attcaagata acagatgtat ctatcacgta tttcttgatt
     6601 tgttgaccat attcgtaata ttcttcaaaa atatcatcga aaacaatcgc tttactgtca
     6661 tacaattttt caaaaagacg attcttttca gcaaggttac gttctaaacg ctcacggaaa
     6721 atatctttat ctaaaagatc tgcaatacga attccaacac gagcagcctt gtccatataa
     6781 gctggaccaa ttcccttaat tgtcgtacca atcttattgt cgcccttagc ttcttcttgc
     6841 aagcgatcca actcgatatg ataaggcaaa ataacatgcg cacgatcaga aatacgcaag
     6901 ttatcagttg ttacaccttc ctcatgaaga tagctcaact cttttacaag agatttagga
     6961 tttacaacca taccattccc aatgacagat attttttcag ggaagaaaat cccagatgga
     7021 atcaagtgca acttaaattt cttaccgtca atcacaatcg tgtgaccagc attatcacca
     7081 ccttggtaac gtgcaattac ttctgcattc gctgaaagga agtctgtaat cttcccttta
     7141 ccttcatcac cccattgggt acctacaaca acaactgaag tcataatttt gtctgagccc
     7201 tcaggctctt cctttctcac atacatggca ggactctcac ctgcaattat atcttacaat
     7261 ttattataat aaaaaatcgc ctttttatca agaagaaaca atagaaagat ttgctatttc
     7321 caactattaa aaaatgattt agaaaaatta ctagctattt actattatct ttccataaaa
     7381 gagtaaatta gttcggaaat ttactaaaat tacctcaaca agaaataaaa ccccgattca
     7441 ttaccaattt ttcaagatac aaacgataag caacacgata atggtaaacg ataaaatccc
     7501 tacgacaacc aatgccatat ctcactaaat aataaattaa aaatttaaaa tgaacatgtt
     7561 cccagtcaaa attatcacca aatgtaggac catactcttc ttcaatacta tcatagaaat
     7621 tagtcatctg ctcataaatt ttttgtaaca taatcaaata ctccttttct tttttataaa
     7681 cttattctaa caaaaaattt tacacattca ctatcaattc ctgaattgtt aaaataccag
     7741 cctcaacaag ataaaaatag gaaaagttga caaaatagaa acaaatttgc tacctaaatt
     7801 tcaaacgatt aaagttctaa aaagaccgcc ttaaaacttt tgggtaaatc ctattagaac
     7861 tataatattt atatatatgt attatggttc tgattttcta gtataaaaaa attcaaacta
     7921 gaattcttct tagaaaaggc cgttttaagt gctatcattg ctcaaaaatg gaggtcgctg
     7981 agacttctat cgtcaagaag aatcatcaaa ttccttgtat catcaaccaa aagattgctc
     8041 agaagttaat tgaaaagact tctatgaccg acattgatca tcagttgtct atttcaactt
     8101 caactgtcat tcgcaagatc aataattttc actttgagca tgatttttcg cgtcttcctg
     8161 agattatgtc ctaggacgtt gaaacagtcc ggggagtgac tgtttcaatc gggagatgga
     8221 gatgagcttt attgctcagg actttgataa actcaatatc ataactgttc ttgagagcag
     8281 aacacaagcc atcatccgaa atcccatgaa tacaaggcta tcaagcgcta ctggaagctc
     8341 attcaacaag atagtcagaa actgagtgat aaacgatttt atcgccctac ttttcgtatg
     8401 cacttgacta ataaagaaat tctagataaa cttttgagct attccgaaga cttgaaacac
     8461 cactataatc tctatcagct cttgcttttc cacctctgtt tcagactttg tttaaaacct
     8521 tcctcaaaga taaagagaaa atcgtcaacg cccttcaatt accttattcc aacgccaaac
     8581 tggaagccac caataatctc atcaaactta tcaagcacaa tgcctttggt tttaggaact
     8641 ttgaaaactt caaaaaagaa aggacgaaat ttgtcctttc tagatcttcg ctttcttcaa
     8701 cccactacag ttgacaaaga accgaaaaat gtctcgcctc taatatagtc aattgaaaca
     8761 agaacaagag aaaagagcct cgtaaaaggt attgcaactt ggtaatacct ttttgaggtt
     8821 ctttttgata taagcccatg ttttctca
//
LOCUS       DAVBCA010000076         8550 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.076, whole genome shotgun sequence.
ACCESSION   DAVBCA010000076 DAVBCA010000000
VERSION     DAVBCA010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8550)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8550)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8550
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.076"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..128
                     /locus_tag="VQU19_001908"
     CDS             <1..128
                     /locus_tag="VQU19_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HET2481107.1"
                     /translation="FQSLNQLEQAIVDYIDYYNNKRIKVKLKGLSPVQYRTKSFG"
     gene            complement(257..460)
                     /locus_tag="VQU19_001909"
     CDS             complement(257..460)
                     /locus_tag="VQU19_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2481108.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(453..1535)
                     /locus_tag="VQU19_001910"
     CDS             complement(453..1535)
                     /locus_tag="VQU19_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HET2481109.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(1661..2443)
                     /locus_tag="VQU19_001911"
     CDS             complement(1661..2443)
                     /locus_tag="VQU19_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HET2481110.1"
                     /translation="MVYTSLSSKDSNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(2443..3786)
                     /locus_tag="VQU19_001912"
     CDS             complement(2443..3786)
                     /locus_tag="VQU19_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HET2481111.1"
                     /translation="MNLKTTLGLLAGRSSHFVLSRLGRGSTLPGKVALQFDKDILQSL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(3885..5201)
                     /locus_tag="VQU19_001913"
     CDS             complement(3885..5201)
                     /locus_tag="VQU19_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HET2481112.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYATVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKKELTAETIVINTGAVSNVLPIPGLATSKNIFDSTGIQSLDKLPEKL
                     GILGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            5394..6615
                     /locus_tag="VQU19_001914"
                     /pseudo
     CDS             5394..6615
                     /locus_tag="VQU19_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
     gene            6814..8388
                     /locus_tag="VQU19_001915"
     CDS             6814..8388
                     /locus_tag="VQU19_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET2481113.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQDIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
BASE COUNT         2454 a         1652 c         1892 g         2552 t
ORIGIN      
        1 cgtttcagtc gcttaatcaa ttggaacaag ctattgtaga ctatattgat tactacaaca
       61 ataaacgaat taaggtaaaa ctaaaaggac ttagtcctgt gcaatacaga actaaatcct
      121 tcggataaat taattgtcta actgtttggg ggcagtacat attcaacacc tgatactatg
      181 cgttttattg tgggaagatt ttcctcattt tctagtgaaa ttgaactttt tctaacatct
      241 tttgatagat gacttcttaa tcaattatca tttccattgt tgtttcttgg ggtttcatcc
      301 cttgtctttg ataaaagcgg agagcaccct cgttatcatt ccagacactt agggttagat
      361 tattgcagcc aatttcttta gcataatagc agaaaaatga caataaaata gcccctagat
      421 attttgaaag gaaagcatag gggctatata gtttaatcaa aataaagcaa atctttgctg
      481 gtgcttgtaa agaggtcgaa gccatccttg gtaacaacac cgcagtcttc aatacgaaca
      541 ccgactttac cagggatata gatacctggt tcaacagaga agcacatgcc ttcttcgatg
      601 accatgtcgt ttccttccat gatagatggg aattcatgga catccatacc gataccatgc
      661 ccgagacggt ggttgaagta ctcaccataa ccagcttttt cgatgacctc acgggcagcg
      721 cggtccactt catgagcagt cacacctggc ttgataaagt caagagcagc ttgttgggct
      781 tcaagagtca agttgtaaat atctttcttg aattggtctg gtttgccgac agcgactgta
      841 cgagtcatat ctgacgcata gccattgacc agaacaccca ggtcaaagag gagaagagca
      901 tcattttcaa ccttattagc tgctggaatg ccgtgtggat tcgcagcatt atcaccagtc
      961 aagaccatgg tatcaaagct catttcataa ccttcacgtt tcatggcaaa gtcgatttgt
     1021 gcgatgatat ctgtctcagt cttatcaaga gaaatattgt caaaaccaac atgaacagcc
     1081 ttgtcagcat aaagacctgc aaccatcatt ttttgcactt catcagctga tttgatgagg
     1141 cgcatgcgtt ggatacgagg agtgaggttg tcaaactcag cagtctcaaa aactgttttc
     1201 aaaccatggt atttggtcaa gatgagattg tcaaactcaa cagcgacacg tttgaagtca
     1261 agttgtggaa gagcatgttt gattttttgc catggatttt cagaatcgac atagcccact
     1321 actgggaagg aaacggtgct acttgcacgt tctacttcaa gagctgggac aaagaggaga
     1381 ggttcctgat ccgctaggac aaagaggaac atttggcgtt catggggatc actgtaaaaa
     1441 ccagtgaggt aattgattgt gacggggtca gatacgacag cgacgtctag tttttctgat
     1501 tcaagatatg ttaggatttg ttgtaattta gacatatgct accttctttc tacccctcta
     1561 ttttggcaaa aaatgagaga aaatgcaagg gagaagggta aaagaaaaga caaaaaactc
     1621 cgacaagata acggagttct ttgatatcat tttcctttgt ttaagaaaag tcagccttgc
     1681 ttttgacgtc actgtactct tcagcgattt cttggctgag aatgtcctca taggcaggga
     1741 gttggatgtc ctgaccatat ttcttcttga gggcagtagt aactaggcga taagccagat
     1801 tggcattacg agagaggata ggcccgtgga agtaggaacc aaagacattc ttataatgaa
     1861 ccccttcacc gaccttttct tcgttgtttc catttccata gacaacctgt cccagcggtt
     1921 tttggtcatc agagaggaag gtacgacctt ggtgattttc aaatccatag taggtttcat
     1981 cgaaatcttc attgtgaatc ttgatgtcac cgataaaacg gttattggtc tggttgagcg
     2041 tgtagtgtcc catgacccct agcccttcga tacgttttcc tgaagcttca acataatatt
     2101 gacccaatag ttggaaacca ccgcagatag ccagaactac accgtcgttt tggatgtagt
     2161 tgtcaatgct ctctttttta gcaggtaggt cgtctgcaat gatactttgt tcaaagtctt
     2221 gaccaccacc gaaaaaggcg atgtcgtagt gattttcatc aaagtcatca tggagagaaa
     2281 cgatgtcaac ggtcacatgg gctcccagtt tttcagccac atacttgagc atgaggatgt
     2341 ttccattgtc cccgtaggta ttcatgagat ttccgtagag gtgggcaatg ttgagctgat
     2401 aggggtaatt gctatctttt gaggaaagtg aagtataaac cattagttca tctcctttct
     2461 aacaatctga cgactagcca gcagttcacg aaattccagc atggcagtat aagttgccag
     2521 aatataggca tgcttgcagt cttgattctc aatggtcttg agaacttgct ccagattact
     2581 cgtttcagtg attttctcag ctggatagcc agtcactcgg aggcgacgag cgatttcaga
     2641 atgacgaaca ccgccagcgt tgatttcagg aatgtccatg tcagtgattt gctcaaagtc
     2701 tgcatcccag atccagctag tgtcaattcc atctgcatag ttggcattaa ggaggacaga
     2761 taggctaaat ggataaggtg ctagtttgat catttcgata gcttgggttg caccgactgg
     2821 atttttaatc aagacaaggg tacattcctt gtcaccgata tgaaaggttt cttggcgtcc
     2881 aaagacagca cggctcttgt caaatccctg tttgatgagt tgggaatctg cgccgaggaa
     2941 acgggcgatg gccacagcag ctagggcgtt atagatatta tagagcccgc cgatttggat
     3001 accgtattct tggccgtcta tgacaaagcg agagcgattg ttggtcaact caaccagttt
     3061 tgtcaaacga tagtcgagat caggacgttt acatccacaa ccttcacaga tataggcacc
     3121 caagtttgca taggtattat gctcatattt gaggatgcct tggcagtcag gacagagaat
     3181 cccttcggta ttgtagtgag ccagttgggc tggtcctttt tccaagtcaa aaccaaaata
     3241 ctctataggg tttggaatag ttggcttgta gaaaagtgga ctgtctccgt taaggagaac
     3301 agtagcagtt ggaacttttc gaatggcatc caatatcatg ttataggtag tatagatttc
     3361 accgaaacgg tccatctggt cacggaagat attagtaatg acaaaaagac taggctggat
     3421 atagtcacag atacgagata gactggcttc gtcaatttcg aggacggcaa tatttttccc
     3481 agtttttgaa gatttggctg ttaggaaggt tgttgcaatc cctgtaatca tgttggcacc
     3541 gcttgggttg gttagaactt gaccataaac ctcttttaaa atgccgacag tgagggcagt
     3601 tgtcagggtt tttccatttg ttccagtgac aacgacaatc tcgtagttct tagctaggct
     3661 ttgtaaaata tctttatcaa attgaagggc gactttccct gggagcgtac ttccacgtcc
     3721 aagacggctt aaaacgaagt gggaagaacg cccagcaaga aggcccaaag tagtttttaa
     3781 gttcatgttt ctattatatc acaaaagagg gaaaagacag atttggtgtt tcgtagaagt
     3841 aaaaacagcc caaagagggc tgtcagttaa gatgagattt caacttaaat cgcaaacaag
     3901 tcattcaagt tctcagccaa ggttgggtga gtgaagattt gttttgtgaa gtaagtgtaa
     3961 ggaatcttgt tgtccatagc aacagtaatg atgttgatga tttcttgaga accttctgag
     4021 aagatgcttg caccaagaat ttcttttgtt tcagtattaa caacagcttt gaaagctccg
     4081 cgaaggtctc catttacgtg accacgaggc atggctgcaa cagggatttc tttcactgcg
     4141 tatggaagtt tcaaatcagc tgcttggctt tcagtcaaac caacttgtga aagtgcaggt
     4201 gtgatgaaca tagtatttgg cacattgaga cggtcctcaa gtgtgtagct gccatctcca
     4261 gcaaggtagc tgtaaacaac acggaagtca tcaagtgaaa tgtaagtaaa ttgaaggcca
     4321 ccgttgacat ctccaactgc aaagacacca ggaacgtttg tttgacagtg tttgtctact
     4381 ttaatagcac cacgttcagt tagttcaata tctgtatttt caagttgaag tggttctaca
     4441 tttggtttgc gtccagttgc gtagagaagg gcgtcgaaac ggtaagtttc gtcttcagtt
     4501 acgacaagca cttggtcacc atcgtttttg atttcagtag tatggatatt ttgaagcaat
     4561 tcaatgccat cttcttccat gtattgttta gcaagagctg cgatggaagg ttctgcacga
     4621 ggtaggaatg tatccaaggc atctaggact gtgaccttgc ttccaagttt gttgtaaagg
     4681 ccggcaaatt caagaccgat atttccgcca ccaaggattc caagtttttc aggtaatttg
     4741 tccaagcttt ggatacctgt tgagtcaaag atgtttttgc ttgtagcaag tccaggaatt
     4801 ggcaagacgt ttgaaacagc accagtgttg atgacgattg tttcagcagt cagttctttc
     4861 ttttcatcac cagcttggat ttcgatgact ttatttgaaa ggaagtgagc ttccgcatca
     4921 aagatatcta cgcctgtacc agcaacagtc gcatagtttt taccgttgag gcgaccagtg
     4981 atcgtgtttt tagtagcaat cacttcttca aaagacaagt ccttttcagc agcaactagc
     5041 aaggttttag ttgggataca accaatgttg atacaagttc caccgtacat agccttgctg
     5101 cgttcaacga gggcaacttt tttgccagct gaagccaatt tacctgctag tgttttacca
     5161 gctttaccaa atccaataac aattaaatcg tatgttaaca tttatcttcc tcctattcga
     5221 atttcattct agcacaagaa aaaaactttt gcacaattct gctacggaaa agacagaaaa
     5281 agataaaaac gctttccaga caaaaaacta gtaatttttt gacaagcttg ataaactaaa
     5341 atcctatcta tttttatata agaaagaata aatgttcgaa aataggaggt tttatgaaat
     5401 cgaatcgtta tattattgcc tttgctgggg tcattttaca cttaatgctg ggttcgactt
     5461 atgcttggag tgtttatcgt aaccctatta ttgaaaaaac gggatgggat caggcttctg
     5521 ttgccttcgc ctttagtcta gcaatctttt gtttgggctt atcggctgca tttatggggc
     5581 gtttggtaga aaaatttggt ccgaaagtca tggggagtct atctgctttt ctatacgcag
     5641 gtggaaatat cttaacagga tttgcaatag accgtcagga actgtggttg ttgtatctag
     5701 cttatggcat tttaggtggg cttggtttgg gagcaggcta tattacccct gtgtcaacga
     5761 ttataaaatg gtttcctgat aaacgtggtc tcgcaacagg tttagcgatt atggggtttg
     5821 gttttgcttc tttattgact agtcccatag cgcaacacct catcgcaggg gtagggattg
     5881 tagaaacttt ttatatttta ggagcaagtt actttattat catgctccta gcttcacaat
     5941 tcattaagcg tccaaatgag caagagcttg caattttatc ttcttcaggg aaagaaaaaa
     6001 cagcctcttt gacgcaagga atggctgcaa atcaggctct aaaaagcaat cggttttata
     6061 tgctttggat tattttcttt atcaacatag cttgtggttt aggcttaatt tcagcggcat
     6121 cgccaatggc acaggagatg gctggcttgt ctacaagtca tgcagcagta atggtgggtg
     6181 ttttggggat tttcaatgga tttggtcgct tgctctgggc gagtttgtct gactatatcg
     6241 gtcgccctct aacctttagt atattactgc ttgtcaatct tttctctctc actttggctc
     6301 tttacagatt ccgttttatt tgtagttgct atgtctattt tgatgacttg ctatggagct
     6361 ggtttttctt tgattccagc ttatctcagt gatatttttg gaaccaagga attggccgct
     6421 ctgcatggtt atattttaac agcttgggca atggctggtt tagcgggacc tattttatta
     6481 gcagagactt ataaaatggc tcattcgtac acacaaacct tgttcgtttt tctcatttta
     6541 tacagtatcg ccttggcttt gtcttattat ctaggtcgtt caatcaaaaa agaaagtcaa
     6601 aaaccgctta catgattttc tgtagaaatg gggctatctt ttgctctggt cttgtgttat
     6661 actagatagg ttgcaaagaa aacagtactt ttcttttgtg gaaaagaagc aacacgattt
     6721 tatatctagt tatatgaaaa tacgtcataa aaagaaaagt ataaactaag ccctataggg
     6781 tggcttcgca ccacctttag aaagaagaat aacgtgaaat ttaatgaatt aaacttgtct
     6841 gctgatttgc tagcagaaat tgaaaaagct ggttttgtag aagctagtcc tatccaagaa
     6901 caaactattc ctttggccct tgaaggcaag gatgttatcg gtcaagctca gactggtaca
     6961 ggaaaaactg cagcctttgg cttgcctacc cttgaaaaaa tccgtacaga agaagcgact
     7021 atccaagctt tggtcatcgc tccaactcgt gaactagctg tccaaagtca agaagaactc
     7081 ttccgctttg gtcgtagtaa gggagtcaaa gtccgttcag tatatggcgg atcaagcatt
     7141 gaaaaacaaa ttaaggctct taaatctggt gcccatatcg tggtgggaac tccaggtcgc
     7201 ctcttggact tgattaaacg caaggccttg aaattacaag acattgaaac ccttatcctt
     7261 gacgaagcgg atgaaatgct taacatgggc ttccttgaag acatcgaagc cattatttcc
     7321 cgtgtacctg agaaccgtca aactttgctt ttctcagcaa ctatgccaga tgccatcaaa
     7381 cgtatcggtg ttcagtttat gaaagcccct gaacatgtca agattgcggc taaggaattg
     7441 acaacagaat tggttgacca gtactatatc cgtgttaagg aacaagaaaa atttgacacc
     7501 atgactcgtc tcatggatgt ggcacaacca gaactcgcta ttgtatttgg tcgtaccaaa
     7561 cgccgtgtgg atgaattgac tcgtggtttg aaaattcgtg gcttccgtgc agaaggaatt
     7621 catggcgacc tagaccaaaa caaacgtctt cgtgtccttc gtgactttaa aaatggcaat
     7681 cttgatgttt tggttgcgac agacgttgca gcgcgtggtt tggatatttc aggtgtgacc
     7741 catgtctaca actacgatat tccacaagat cctgagagtt atgttcaccg tatcggtcgt
     7801 acaggtcgtg ctggtaagtc aggtcaatct attacttttg ttgctccaaa cgaaatgggt
     7861 taccttcaaa tcattgaaaa cttgactaag aaacgcatga aaggtctcaa acctgcaagt
     7921 gtagaagaat ccttccaatc aaaaaaacag gtagctctca agaaaatcga acgtgatttt
     7981 gcagatgaaa ccattcgtgc caactttgag aaatttggta aggatgctcg caaattggct
     8041 gctgagttta ctccagaaga attggcaatg tatatcttga gtctgacagt ccaagaccca
     8101 gatagccttc cagaagtgga gattgcacgt gaaaaaccac taccgtttaa accatcaggt
     8161 aatggtttcg gtggtaaagc taagggaggt cgtggaggcc gtcgtgggga cgaccgtcga
     8221 gagcgtgatc gccgtggcaa tggtcgccgt gatgagttca aaaaaggaag tcgtggcaac
     8281 gatcgttttg ataaggaaaa acgttaccgt aaggataata aaaaaccacg caatacttta
     8341 agcgaaaagc aaacaggctt tgttattcgt aacaaaggcg ataaataaga aaaagcggtt
     8401 caaaatgaat cgctttttta tataaggaga ccgaatgtga aaagacaaat aaaattacta
     8461 tattatcttt tataatgtta tgatacacaa aaataggcaa cttgtcaata gaaaaggaac
     8521 aatttaatta aaaatattct ggtttttaat
//
LOCUS       DAVBCA010000077         8107 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.077, whole genome shotgun sequence.
ACCESSION   DAVBCA010000077 DAVBCA010000000
VERSION     DAVBCA010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8107)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8107)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8107
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.077"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            120..497
                     /locus_tag="VQU19_001916"
     CDS             120..497
                     /locus_tag="VQU19_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HET2481114.1"
                     /translation="MICQFIRDMLDLPAKNVTILEGSNIHVLPSMPYSAQDFYTSIDV
                     LAELDNGIQVIIEIQVHHQNFFINRLWAYLCSQVNQNLEKIRQREGDTHQSYKQIALV
                     YAIAIVDSNYFSDDLAFHSFIVK"
     gene            732..2123
                     /locus_tag="VQU19_001917"
     CDS             732..2123
                     /locus_tag="VQU19_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HET2481115.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKIEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIDQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKHQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            2237..3079
                     /locus_tag="VQU19_001918"
     CDS             2237..3079
                     /locus_tag="VQU19_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HET2481116.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQEQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     IAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERETLKTIAVQSGAPRVD
                     DVDF"
     gene            3352..4113
                     /locus_tag="VQU19_001919"
     CDS             3352..4113
                     /locus_tag="VQU19_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HET2481117.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDFNAATQIIRESAVPAYTNNRRMVMAPDLAVWKELYLYQLMDYECSQQTQAI
                     ESHYHSLSENFLLQIVGHELAHWSEHFLDDFDGYDSYIWFEEGMVEYISRKYFLTEEE
                     FQAEKICNQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWRSFLTVDKLVENLG
                     SVQAVLDSYHLWANTEKTFPLLDWFVQQKLIEKEI"
     gene            4483..5400
                     /gene="glyQ"
                     /locus_tag="VQU19_001920"
     CDS             4483..5400
                     /gene="glyQ"
                     /locus_tag="VQU19_001920"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HET2481118.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRVKLLAEDAE"
     gene            5660..7696
                     /locus_tag="VQU19_001921"
     CDS             5660..7696
                     /locus_tag="VQU19_001921"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HET2481119.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQAVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSELFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            7738..7995
                     /locus_tag="VQU19_001922"
     CDS             7738..7995
                     /locus_tag="VQU19_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HET2481120.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
BASE COUNT         2554 a         1431 c         1794 g         2328 t
ORIGIN      
        1 gctttctttt ccgaataaat agatagaagc atagaatcta gcaaacctag atttaaaaat
       61 gtgctataat agaaggagga aaaggaggat tctcagacat ccaggtatca gcccaactaa
      121 tgatttgtca atttatccgc gatatgctgg acttgccagc aaaaaatgtg acgattttgg
      181 agggaagtaa cattcacgtc ttgccttcca tgccctactc agcgcaagat ttctatacta
      241 gtatagacgt cttggcggag ttagataatg gaatccaagt tatcatcgaa attcaggttc
      301 atcatcagaa ttttttcatc aatcgcctat gggcttatct gtgcagtcag gttaatcaaa
      361 acctagaaaa aattcgccaa cgtgaaggtg atacccacca gagctacaaa caaatcgcac
      421 tagtatacgc tatcgcaatt gtcgatagta attacttctc agatgaccta gcttttcata
      481 gttttatagt aaaatgaaat gagaacagga caaatcgatc aggacagtca aatcgatttc
      541 taacaatgtt ttagaagtat aggtctacta ttctagcttc aatctactag aaattccata
      601 gatagaaaac tacataatct ctacagatac ggatgttgga gttgatgtaa gatgctttgg
      661 cttgctagag gaattgtgga ttgccaaatt gtatcattga aattattgct caaatttgtt
      721 atgatataaa tatgaataaa agtagactag gacgtggcag acacgggaaa acgagacatg
      781 tattattggc tttgattggt attttagcaa tttctatttg cctattaggc ggatttattg
      841 cttttaagat ctaccagcaa aaaagttttg agcaaaagat tgaatcgctc aaaaaagaga
      901 aagatgatca attgagtgag ggaaatcaga aggagcattt tcgtcagggg caagccgaag
      961 tgattgccta ttatcctctc caaggggaga aagtgatttc ctctgttagg gagctgataa
     1021 atcaagatgt taaggacaag ctagaaagta aggacaatct tgttttctac tatacagagc
     1081 aagaagagtc aggtttaaag ggagtcgtta atcgtaatgt gaccaaacaa atctatgatt
     1141 tagttgcttt taagattgaa gagactgaaa agaccagtct aggaaaggtt cacttaacag
     1201 aagatgggca accttttaca cttgaccaac tgttttcaga tgctagtaag gctaaggaac
     1261 agctgataaa agagttgacc tccttcatag aggataaaaa aatagatcaa gaccagagtg
     1321 agcagattgt aaaaaacttc tctgaccaag acttgtctgc atggaatttt gattacaagg
     1381 atagtcagat tatcctttat ccaagtcctg tggttgaaaa tttagaagag atagccttgc
     1441 cagtatctgc tttctttgat gttatccaat cttcgtactt actcgaaaaa gatgcggcct
     1501 tgtaccaatc ttactttgat aagaaacatc aaaaagttgt cgctctaacc tttgatgatg
     1561 gtccaaatcc agcaacgacc ccgcaggtat tagagaccct agctaaatat gatattaaag
     1621 cgactttctt tgtgcttggg aaaaatgttt ctgggaatga ggacttggtg aagaggataa
     1681 aatctgaagg tcatgttgtt ggaaaccata gttggagcca tccgattctc tcgcaactct
     1741 ctcttgatga agctaaaaag cagattactg atactgagga tgtgctaact aaagtgctgg
     1801 gttctagttc taaactcatg cgtccacctt atggtgctat tacagatgat attcgcaata
     1861 gcttggattt gagctttatc atgtgggatg tggatagtct ggactggaag agtaaaaatg
     1921 aagcatctat tttgacagaa attcagcatc aagtagctaa cggctctatc gttttgatgc
     1981 atgatattca cagtccgaca gtcaatgcct tgccaagggt cattgagtat ttgaaaaatc
     2041 aaggttatac ctttgtgacc ataccagaga tgctcaatac tcgcctaaaa gctcatgagc
     2101 tgtactatag tcgtgatgaa taagcaagaa aaaataggtc tgttagatat ttgacagact
     2161 tattttttac agaatatagt actacttaaa aaatgtttta tgctataatt gatgaataaa
     2221 atagaaggag aagcatatga atacctatca attaaataat ggagtagaaa ttccagtatt
     2281 gggatttgga acttttaagg ctaaggatgg agaagaagcc tatcgtgcag tgttagaagc
     2341 cttgaaggct ggttatcgtc atattgatac ggcggcgatt tatcagaatg aagaaagtgt
     2401 tggtcaagca atcaaagata gcggagttcc acgtgaagaa atgttcgtaa ctaccaagct
     2461 ttggaatagt cagcaaacct atgagcaaac tcgtcaagct ttggaaaaat ctatagaaaa
     2521 actgggcttg gattatttgg atttgtattt gattcattgg ccgaacccaa aaccgctcag
     2581 agaaaatgac gcatggaaaa ctcgcaatgc ggaagtttgg agagcgatgg aagacctcta
     2641 tcaagaaggg aaaatccgtg ctatcggcgt tagcaatttt cttccccatc atttggatgc
     2701 cttgcttgaa actgcaacta tcgttcctgc ggtcaatcaa gttcgcttgg cgccaggtgt
     2761 gtatcaagaa caagtcgtag cttactgtcg tgaaaaggga attttattgg aagcttgggg
     2821 gccttttggt cagggagaac tatttgatag caagcaagtg caagaaatcg cagcaaatca
     2881 cggaaaatcg attgctcaga tagccttggc ctggagcttg gcagaaggat ttttaccact
     2941 tccaaaatct gtcacaacct ctcgtattca agctaatctt gattgctttg gaattgaact
     3001 gagtcatgag gagagagaaa ccttaaaaac gattgctgtt caatcgggtg ctccacgagt
     3061 tgatgatgtg gatttctaga aaatcataaa aagaattgta cattattcta atttttgata
     3121 taatagtcag caggaaagaa agtcttatgg cgttcttcaa gcgagcttgg gatagtggga
     3181 gccaagtagg gcaaaataat gagctggcgc tttctgtagt attttcaaaa acaatgaagt
     3241 aataaattag ggtggaaccg cgtttctgac gcccctaggt taaatcaacc taggattgtc
     3301 ggacgcggtt cttttgctta ttcagtctat tgtgtgaaag aaaggagagc cgtggacaac
     3361 ctttatcttg taaaagacga tagtcaacta gctacatttc gtgattttgt agtaagaaat
     3421 actgaaaagt tgaaagatta tcaatctttt ttaaagaatg aacttgcagt ctgtgattta
     3481 ccgcaagccg ttatttggtc agattttaat gctgctacac agattattag ggaaagcgct
     3541 gttccagcct atacaaataa tagacgaatg gttatggcgc ctgatttagc tgtttggaaa
     3601 gagttgtatt tgtatcaatt gatggactac gagtgttctc agcaaactca agcaatagaa
     3661 agtcactatc attctttatc tgaaaatttc ctcttacaga ttgtaggaca tgagttagct
     3721 cattggtcgg agcatttttt agatgatttt gatggttatg actcttatat ctggttcgaa
     3781 gaggggatgg ttgaatatat tagtcgcaag tatttcttga cagaagagga atttcaagcg
     3841 gaaaaaattt gtaatcaatc tctcgtagaa ctttttcaga agaagtatgg ttggcattca
     3901 ttgaatgatt ttggttcttc gacttatgat aagaactatg caagtatttt ttatgaatac
     3961 tggcgcagct ttttgacagt agataagttg gtagaaaatt taggtagtgt acaagcggtc
     4021 ttagattctt atcatttatg ggcaaataca gaaaaaactt ttcccttgtt agattggttt
     4081 gttcagcaga aattaattga aaaagaaata taaaaactaa aggagtaaac aatgtctaag
     4141 aaattgacat ttcactgcgt cagtggcaga aacctcctta cagtcggact gccccacgct
     4201 cagcactaga gtgcctgagc tagacgcagt actaactcgt cttgcctcgt atgatcgacg
     4261 aggcagactc atgtcgcaag taattatttt ttattaagga gtaaacaatg tctaagaaat
     4321 taacatttca ctgcatcagt ggcagaaacc tccttacagt cggactgccc cacgctcagc
     4381 accctagtgc tgagctagac gcagtactaa ctcgtcttgc ctcgtataat cgacgaggca
     4441 gactcgtgtc gcaagaaatc attttttatt aaggagtaaa caatgtctaa gaaattaaca
     4501 tttcaagaaa ttattttgac tttgcaacaa ttttggaatg accaaggttg tatgcttatg
     4561 caggcttatg acaatgaaaa aggtgcgggg acaatgagtc cttacacttt ccttcgtgct
     4621 atcggacctg agccatggaa tgcagcttat gtagagccat cacgtcgtcc tgctgacggt
     4681 cgttatgggg aaaaccctaa ccgtctctac caacaccacc aattccaggt ggtcatgaag
     4741 ccttctccat caaatatcca agaactttac cttgagtctt tggaaaaatt gggaatcaat
     4801 cctttggagc acgatattcg ttttgttgag gacaactggg aaaacccatc aactggttca
     4861 gctggtcttg gttgggaagt ttggcttgac ggaatggaaa tcactcagtt cacttatttc
     4921 caacaagtcg gtggattggc aactggccct gtgactgcgg aagttaccta tggtttggag
     4981 cgcttggctt cttacattca agaagtagac tctgtctatg atatcgagtg ggctgatggt
     5041 gtaaaatacg gagaaatctt tatccagcct gagtatgagc actcaaaata ttcatttgaa
     5101 atttcggacc aagaaatgtt gcttgaaaac tttgataagt ttgaaaaaga agctggtcgt
     5161 gcattagaag aaggcttggt acaccctgcc tatgactatg ttctcaaatg ttcacatacc
     5221 tttaatctgc ttgacgcgcg tggtgccgta tctgtaacag agcgtgcagg ctatatcgct
     5281 cgtatccgta acttggcccg tgttgtagcc aaaacctttg ttgcagaacg caaacgccta
     5341 ggttacccac ttttggatga agaaacacga gttaaacttt tagcagaaga cgcagaatag
     5401 tgagtaatac tgtactctaa aatcgttaga ggcaagtcga agacttgcta gagggatatg
     5461 caccgccgta ctgttatgtg gggatttttg aaaccttagg ttcaaaaatc agtcagctaa
     5521 atccactttg atgagattgt tggaaatctt gataaattta gcattggatt tccatacaga
     5581 ctcacagagt tagttagcga cgtccccagt acctaaggtg catatcaaaa aagattgaag
     5641 aaaatgtaaa ggaaaaaaca tgacaaaaaa cttattagta gaactcggtc ttgaagaatt
     5701 accagcctat gttgtcacac caagtgaaaa acaactaggc gaaaaaatgg cagccttcct
     5761 caaggaaaac cgcctgtctt ttgaagccat tcaaaccttc tcaacaccac gtcgtttggc
     5821 tgttcgtgtg actggtttat cagacaaaca gtctgatttg acagaagatt tcaagggacc
     5881 agcaaagaaa attgccttgg atagtgatgg aaactttacc aaagcagctc aaggatttgt
     5941 ccgtggaaaa ggcttgactg ttgaagatat cgaattccgt gaaatcaagg gtgaagaata
     6001 tgtctatgtc actaaggaag aagttggtca agcagttgaa gccattgttc ctggtgttgt
     6061 agatgtcttg aagtcattga ctttccctgt cagcatgcac tgggctggaa atagctttga
     6121 atacattcgt cctgtccaca ctttaactgt tctcttggat gagcaagagt ttgacttgga
     6181 tttccttgat atcaagggaa gtcgtgtgag ccgtggccat cgtttcttgg ggaaagaaac
     6241 caaaattcag tcagcattga gctatgaaga agaccttcgt aagcagtttg taatcgcaga
     6301 tccatgtgaa cgtgagcaaa tgattgttga ccaaatcaag gaaattgagg caaaacatgg
     6361 tgtacgtatc gaaattgatg cggatttgct gaatgaagtc ttgaatttgg ttgaataccc
     6421 aactgccttc atgggaagtt ttgatgctaa ataccttgaa gttccagaag aagtcttggt
     6481 gacttctatg aaggaacacc agcgttactt tgttgttcgt gatcaagatg gaaaactctt
     6541 gccaaacttc atttctgttc gtaacggaaa cgcagagcgt ttgaaaaatg tcattaaagg
     6601 aaatgaaaaa gtcttggtag cccgcttgga agacggagaa ttcttctggc gtgaagacca
     6661 aaaattggtg atttcagatc ttgttgaaaa attaaacaat gtcaccttcc atgagaagat
     6721 tggttccctt cgtgaacaca tgattcgtac gggtcaaatc actgtacttt tggcagaaaa
     6781 agctggtttg tcagtggatg aaacagttga ccttgctcgt gcagcagcca tttacaagtt
     6841 tgacttattg acaggtatgg ttggtgaatt tgacgaactc caaggaatta tgggtgaaaa
     6901 atacaccctt cttgctggtg aaactccagc ggtggcagct gctattcgtg aacactacat
     6961 gcctacatca gctgaaggag aacttccaga gagcaaggtc ggcgcagttc tagccattgc
     7021 agacaaattg gatacgattt tgagtttctt ctcagtagga ttgattccat caggttctaa
     7081 tgacccttat gcccttcgtc gtgcaactca aggtgtggtt cgtatcttgg atgcctttgg
     7141 ttggcacatt gctatggatg agctgattga tagcctttat gcattgaaat ttgacagttt
     7201 gacttatgaa aataaagcag aggttatgga ctttatcaag gctcgtgttg ataagatgat
     7261 gggctctact ccaaaagata tcaaggaagc agttcttgca ggttcaaact ttgttgtggc
     7321 agatatgttg gaagcagcaa gtgctctcgt agaagtaagc aaggaagaag attttaaacc
     7381 atctgttgaa tcactttctc gtgcctttaa cctggctgag aaggcagaag gggttgctac
     7441 agttgattca gaactatttg agaatgacca agaaaaagct ttggcagaag cagtagaaac
     7501 actcgtttta tcaggacctg caagtcagca attgaaacaa ctctttgcgc ttagcccagt
     7561 cattgatgct ttctttgaaa atactatggt aatggctgaa gatcaggctg tccgtcaaaa
     7621 tcgtttggca atcttgtcac aactaaccaa gaaagcagct aagtttgctt gttttaacca
     7681 aattaacact aaataaaatt tgataaacgg actttatctt attacaaagg agaagaaatg
     7741 gatccgaaaa aaattgctcg tatcaatgag cttgctaaaa agaaaaaaac agaaggctta
     7801 acaccagaag aaaaagtgga acaagccaaa ctacgtgagg agtacatcga aggttatcgc
     7861 cgcgctgttc gtcaccacat tgaaggaatc aaaattgtgg acgaagaagg aaacgatgtt
     7921 acaccagaaa aactacgcca agtacaacgt gaaaaaggat tacatggccg tagtcttgat
     7981 gacccaaatt cataatatgt actctttctt ttaacaaaga tagatgaaac gataacaaag
     8041 agactagcag tttgtgtttg ctagtctttt ttcgctaaaa aaggaaccat aatggttcct
     8101 aaaaact
//
LOCUS       DAVBCA010000078         7660 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.078, whole genome shotgun sequence.
ACCESSION   DAVBCA010000078 DAVBCA010000000
VERSION     DAVBCA010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7660)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7660)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7660
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.078"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            226..6657
                     /locus_tag="VQU19_001923"
     CDS             226..6657
                     /locus_tag="VQU19_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HET2481121.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALNISDKEKV
                     VVDKETENKEKHEDIHNAIETSQDFKEKKTAVIEGKEVVSKNPVTDNNTSNEEARIKE
                     DSNQSQGDHTDSFVNKNTENPKKEDKVVYIAEFKDKESGEKAIKQLSNLKNTKVLYTY
                     DRIFNGSAIETTPDNLDKIKQIEGISSVERAQKVQPMMNHARKEIGVEEAIDYLKSIN
                     APFGKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKI
                     PHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQ
                     IFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRAL
                     RKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQT
                     VEFDKVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDL
                     RGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGT
                     KSQVFSISGDDGVKLWNMINPNKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVG
                     DEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVIN
                     GKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQ
                     NTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGS
                     ISLKEIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPYGK
                     QIVPEIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESV
                     EEMEALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGK
                     PKIPGTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNQGINAPSSSG
                     SKIANIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVIS
                     REHFIRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATK
                     IRGQFEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLIT
                     KDTYHKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYA
                     GEGQGRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFANHADEKG
                     MISYYLVDPDKDASKYEKLGEISEDKLKNAKSPEENTNNNQAKDEDSKPDEKSSVEGE
                     ASLEINKTISTIREFENKDLKKLIKKKFREVDDFTSETGKRIEEYDYKYDDKGNIIAY
                     DDGSALQYETEKLDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNSYKSIEI
                     KATKYDSHSKTMIFDLYANINDIVDGLAFAGDMRLFVKDDNQIKAETKIRMPEKNKET
                     KAEYPYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKGY
                     ALKVTTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRSTQ
                     AVLMSALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDKS
                     NVEAIKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWE
                     LRVNESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMDG
                     NVYLQTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKRN
                     NGFDGEIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDTG
                     EVSELKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKKD
                     AGYVINLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDLQ
                     REDHSQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIVG
                     IFLGLKKKNQD"
     gene            complement(6948..7294)
                     /locus_tag="VQU19_001924"
                     /pseudo
     CDS             complement(6948..7294)
                     /locus_tag="VQU19_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(7389..7574)
                     /locus_tag="VQU19_001925"
                     /pseudo
     CDS             complement(7389..7574)
                     /locus_tag="VQU19_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            7578..7660
                     /locus_tag="VQU19_001926"
                     /pseudo
     CDS             7578..7660
                     /locus_tag="VQU19_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000646892.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2958 a         1055 c         1480 g         2167 t
ORIGIN      
        1 taatcttatt ttttaacgtg tgctaaaaaa taaattaatg catgttaatt tttcttgaat
       61 taaatttttt taaatgatat actgttttta tggagagata acaattatat ataaatgtac
      121 tactctattt cctagataat acttagtaaa actttttata acaaaggcta gcaaagttaa
      181 agtttattat ctattggaag ttaaataaat atgtaaggaa ttaaaatgaa aaaaagtaca
      241 gtattgtcat taaccacagc tgcagttatt ttagcagcct atgcccctaa tgaggtagtc
      301 ttagcagaca catctagctc tgaagatgct ttaaacatct ctgataaaga aaaagtagta
      361 gtagataagg aaacagaaaa taaagagaaa catgaagata ttcataatgc tatagaaact
      421 tcacaggatt ttaaagagaa gaaaacagca gtcattgagg gaaaagaagt tgttagtaaa
      481 aatcctgtga cagacaataa cactagcaat gaagaagcaa gaatcaaaga agattccaat
      541 caatcccaag gagatcatac ggactcattt gtgaataaaa acacagaaaa tcccaaaaaa
      601 gaagataaag ttgtctatat tgctgaattt aaagataaag aatctggaga aaaagcaatc
      661 aagcaactat ccaatcttaa gaatacaaaa gttttatata cttatgatag aatttttaac
      721 ggtagtgcca tagaaacaac tccagataac ttggacaaaa ttaaacaaat agaaggtatt
      781 tcatcggttg aaagggcaca aaaagtccaa cccatgatga atcatgccag aaaggaaatt
      841 ggagttgagg aagctattga ttacctaaag tctatcaatg ctccgtttgg gaaaaatttt
      901 gatggtagag gtatggtcat ttcaaatatc gatactggaa cagattatag acataaggct
      961 atgagaatcg atgatgatgc caaagcctca atgagattta aaaaagaaga cttaaaagga
     1021 actgataaaa attattggtt gagtgataaa atccctcatg cgttcaatta ttataatggt
     1081 ggcaaaatca ctgtagaaaa atatgatgat ggaagggatt attttgaccc acatgggatg
     1141 catattgcag ggattcttgc tggaaatgat actgaacaag atatcaaaaa ctttaacggc
     1201 atagatggaa ttgcacctaa tgcacaaatt ttctcttaca aaatgtattc tgacgcagga
     1261 tctgggtttg cgggtgatga aacaatgttt catgctattg aagattctat caaacacaac
     1321 gttgatgttg tttcggtatc atctggtttt acaggaacag gtcttgtagg tgagaaatat
     1381 tggcaagcta ttcgggcatt aagaaaagca ggcattccaa tggttgtcgc tacgggtaac
     1441 tatgcgactt ctgcttcaag ttcttcatgg gatttagtag caaataatca tctgaaaatg
     1501 accgacactg gaaatgtaac acgaactgca gcacatgaag atgcgatagc ggtcgcttct
     1561 gctaaaaatc aaacagttga gtttgataaa gttaacatag gtggagaaag ttttaaatac
     1621 agaaatatag gggccttttt cgataagaat aaaatcacaa caaatgaaga tggaacaaaa
     1681 gctcctagta aattaaaatt tgtatatata ggcaaggggc aagaccaaga tttgataggt
     1741 ttggatctta ggggcaaaat tgcagtaatg gatagaattt atacaaagga tttaaaaaat
     1801 gcttttaaaa aagctatgga taagggtgca cgcgccatta tggttgtaaa tactgtaaat
     1861 tactacaata gagataattg gacagagctt ccagctatgg gatatgaagc ggatgaaggt
     1921 actaaaagtc aagtgttttc aatttcagga gatgatggtg taaagctatg gaacatgatt
     1981 aatcctaata aaaaaactga agtcaaaaga aataataaag aagattttaa agataaattg
     2041 gagcaatact atccaattga tatggaaagt tttaattcca acaaaccgaa tgtaggtgac
     2101 gaaaaagaga ttgactttaa gtttgcacct gacacagaca aagaactcta taaagaagat
     2161 atcatcgttc cagcaggatc tacatcttgg gggccaagaa tagatttact tttaaaaccc
     2221 gatgtttcag cacctggtaa aaatattaaa tccacgctta atgttattaa tggcaaatca
     2281 acttatggct atatgtcagg aactagtatg gcgactccaa tcgtggcagc ttctactgtt
     2341 ttgattagac cgaaattaaa ggaaatgctt gaaagacctg tattgaaaaa tcttaaggga
     2401 gatgacaaaa tagatcttac aagtcttaca aaaattgccc tacaaaatac tgcgcgacct
     2461 atgatggatg caacttcttg gaaagaaaaa agtcaatact ttgcatcacc tagacaacag
     2521 ggagcaggcc taattaatgt ggccaatgct ttgagaaatg aagttgtagc aactttcaaa
     2581 aacacggatt ctaaaggttt ggtaaactca tatggttcca tttctcttaa agaaataaaa
     2641 ggtgataaaa aatactttac aatcaagctt cacaatacat caaacagacc tttgactttt
     2701 aaagtttcag catcagcgat aactacagat tctctaactg acagattaaa acttgatgaa
     2761 acatataaag atgaaaaatc tccatatggt aagcaaattg ttccagaaat tcacccagaa
     2821 aaagtcaaag gagcaaatat cacatttgag catgatactt tcactatagg cgcaaattct
     2881 agctttgatt tgaatgcggt tataaatgtt ggagaggcca aaaacaaaaa taaatttgta
     2941 gaatcattta ttcattttga gtcagtggaa gaaatggaag ctctaaactc caacgggaag
     3001 aaaataaact tccaaccttc tttgtcgatg cctctaatgg gatttgctgg gaattggaac
     3061 cacgaaccaa tccttgataa atgggcttgg gaagaagggt caagatcaaa aacactggga
     3121 ggttatgatg atgatggtaa accgaaaatt ccaggaacct taaataaggg aattggtgga
     3181 gaacatggta tagataaatt taatccagca ggagttatac aaaatagaaa agataaaaat
     3241 acaacatccc tggatcaaaa tccagaatta tttgctttca ataaccaagg gatcaacgct
     3301 ccatcatcaa gtggttctaa gattgctaac atttatcctt tagattcaaa tggaaatcct
     3361 caagatgctc aacttgaaag aggattaaca ccttctccac ttgtattaag aagtgcagaa
     3421 gaaggattga tttcaatagt aaatacaaat aaagagggag aaaatcaaag agacttaaaa
     3481 gtcatttcga gagaacactt tattagagga attttaaatt ctaaaagcaa tgatgcaaag
     3541 ggaatcaaat catctaaact aaaagtttgg ggtgacttga agtgggatgg actcatctat
     3601 aatcctagag gtagagaaga aaatgcacca gaaagtaagg ataatcaaga tcctgctact
     3661 aagataagag gtcaatttga accgattgcg gaaggtcaat atttctataa atttaaatat
     3721 agattaacta aagattaccc atggcaggtt tcctatattc ctgtaaaaat tgataacacc
     3781 gcccctaaga ttgtttcggt tgatttttca aatcctgaaa aaattaagtt gattacaaag
     3841 gatacttatc ataaggtaaa agatcagtat aagaatgaaa cgctatttgc gagagatcaa
     3901 aaagaacatc ctgaaaaatt tgacgagatt gcgaacgaag tttggtatgc tggcgccgct
     3961 cttgttaatg aagatggaga ggttgaaaaa aatcttgaag taacttacgc aggtgagggt
     4021 caaggaagaa atagaaaact tgataaagac ggaaatacca tttatgaaat taaaggtgcg
     4081 ggagatttaa ggggaaaaat cattgaagtc attgcattag atggttctag caatttcaca
     4141 aagattcata gaattaaatt tgctaatcat gctgatgaaa aggggatgat ttcttattac
     4201 ctagtagatc ctgacaaaga tgcttctaaa tatgaaaaac ttggtgaaat ttctgaagat
     4261 aaactcaaaa atgcaaagag cccagaggaa aataccaata ataatcaagc taaggatgaa
     4321 gattcaaaac cagatgaaaa aagttcagtt gagggagaag ctagccttga aataaataaa
     4381 actatttcaa caattagaga gtttgaaaat aaagacctaa agaaactcat taaaaagaaa
     4441 tttagagaag ttgatgattt tacaagtgaa actggtaaga gaatagagga atacgattat
     4501 aaatacgatg ataagggaaa tattattgct tatgacgatg gtagtgcctt acaatatgaa
     4561 actgaaaaac ttgacgaaat aaaatcaaaa atttatggtg ttctaagccc atctaaagat
     4621 ggacactttg aaattcttgg aaagataagc aatgtttcta aaaatgccaa ggtatattat
     4681 ggaaatagct ataaatcgat agaaatcaaa gcgactaagt atgattcaca ttcaaaaacg
     4741 atgatatttg atttatacgc taatattaat gatattgtag atggattagc ttttgctgga
     4801 gatatgagat tatttgttaa agatgacaat caaataaaag ctgaaactaa gattagaatg
     4861 cctgaaaaaa ataaggaaac taaagcagaa tatccctatg tatcaagtta tgggaatgta
     4921 atcgaattag gagaaggaga tctttcaaag aacaaaccag acaatttaac taaaatggaa
     4981 tctggtaaaa tctattctga ttcagaaaaa caacaatatc tgttaaagga taacatcatt
     5041 ctaagaaaag gctatgcact aaaagtgact acctataatc ctggaaaaac ggatatgtta
     5101 gaaggaaatg gagtctatag caaggaagat atagcaaaaa tacaaaaggc caatcctaat
     5161 ctaagagtcc tttcagaaac aacaatttat gctgatagta gaaatgttga agatggaaga
     5221 agtacccaag ctgtattaat gtcggctttg gacggcttta acattataag gtatcaagtg
     5281 tttacattta aaatgaacga taaaggggaa gctatcgata aagacggaaa tcttgtgaca
     5341 gattcttcta aacttgtatt atttggtaag gatgataaag aatacactgg agaggataag
     5401 tccaatgtag aagctataaa agaagatggc tccatgttat ttattgatac caaaccagta
     5461 aacctttcaa tggataagaa ctactttaat ccatctaaat ctaataaaat ttatgtacga
     5521 aatccagaat tttatttaag aggtaagatt tctgataagg gtggttttaa ctgggaattg
     5581 agagttaatg aatcggttgt agataattat ttaatctacg gagatttaca cattgataac
     5641 actagagatt ttaatattaa gctgaatgtt aaagacggtg acatcatgga ctggggaatg
     5701 aaagactata aagcaaacgg atttccagat aaggtaacag atatggatgg aaatgtttat
     5761 cttcaaactg gctatagcga tttgaatgct aaagcagttg gagtccacta tcagttttta
     5821 tatgataatg ttaaacccga agtaaacatt gatcctaagg gaaatactag tatcgaatat
     5881 gctgatggaa aatctgtagt ctttaacatc aatgataaaa gaaataatgg attcgatggt
     5941 gagattcaag aacaacatat ttatgtaaat ggaaaagaat atacatcatt tgatgatatt
     6001 aaacaaataa cagacaagac actaaacatt aagattgttg taaaagattt tgcaagaaat
     6061 acaaccgtaa aagaattcat tttaaataaa gatacgggag aggtaagtga attaaaacct
     6121 catagggtaa ctgtgaccat tcaaaatgga aaagaaatga gttcaacgat agtgtcggaa
     6181 gaagatttta ttttacctgt ttataagggt gaattagaaa aaggatacca atttgatggt
     6241 tgggaaattt ctggtttcga aggtaaaaaa gacgctggct atgttattaa tctatcaaaa
     6301 gataccttta taaaacctgt attcaagaaa atagaggaga aaaaggagga agaaaataaa
     6361 cctacttttg atgtatcgaa aaagaaagat aacccacaag taaaccatag tcaattaaat
     6421 gaaagtcaca gaaaagagga tttacaaaga gaagatcatt cacaaaaatc tgattcaact
     6481 aaggatgtta cagctacagt tcttgataaa aacaatatca gtagtaaatc aactactaac
     6541 aatcctaata agttgccaaa aactggaaca gcaagcggag cccagacact attagctgcc
     6601 ggaataatgt ttatagtagg aatttttctt ggattgaaga aaaaaaatca agattaagac
     6661 aaaagctata gaaaaaaatg gtttatgtac tgagattaga tagtgaggtg atgacatagt
     6721 tttgtgaaaa cagccattta taactcaatt atttagttta cttcactatt gatactattt
     6781 ggagttatta atggacttag tttagataac taatgaattg attgaaaggg ttagtattga
     6841 caatattggt catattgatt agaaaataga gtctatcaaa atttaaaggc taatagaggt
     6901 gatgagacaa tttcggctct ttgtcaactg tagtgggttg aagtcagcta agctcgagaa
     6961 aggacaaatt ttgtcctttc ttttttgata ttcagagcga tgaaaatccg ttttttgaag
     7021 ttttcaaagt ttcgaaaacc aaaggcattg cgcttgataa gtttgatgag attattggtc
     7081 gcttccagtt tggcattaga atagtgtagt tgaagggcat tgacaatctt ctctttatct
     7141 ttgaggaagg ttttagagga tgaacctgat tcagattgtc ctcaatgagt ccgaaaaatt
     7201 tgtcaggctc cttattctga aagtgaaaaa gcaagagttg atagagatta tagtggtgtt
     7261 tcaagtcttc tgaatagctc aaaagtttat ctatagtaga ttgaaactag aatagtacac
     7321 ctctgcttct aaaacattgt tagaaatcga tttgactgtc ctgaatgatt tgtcctgtta
     7381 ttatttcatt ttactataaa tccacgttta cgaatctctt tccacacttg ttcaatgggg
     7441 ttcatctctg gtgtgtatgg aggaataaat gcaaaaccaa tattagtcgg aatctttaag
     7501 gtacttgatt tatgccatat agcattgtcc ataacgagta aaagataatc atctggataa
     7561 gcttgtgaaa gctcctattc ctaaagcccc tttataacct cttgcgagag agactattga
     7621 ctcagccctt acttcatgcg gatgaaactt cttatcgggt
//
LOCUS       DAVBCA010000079         7489 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.079, whole genome shotgun sequence.
ACCESSION   DAVBCA010000079 DAVBCA010000000
VERSION     DAVBCA010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7489)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7489)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7489
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.079"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..1038
                     /locus_tag="VQU19_001927"
     CDS             <1..1038
                     /locus_tag="VQU19_001927"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018351.1"
                     /note="Produces ATP from ADP in the presence of a proton
                     gradient across the membrane. Subunit I is part of the
                     membrane proton channel; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HET2481122.1"
                     /translation="IKVMDERFGHSIYIYESETLSDNQDEIPIKLTNHSLIEPFELLT
                     EMYALPKYYEKDPTPVLAPFYFTFFGMMVADLGYGLLLFLGTMLALKIFHLPSETKRF
                     LKFFNILGVAVAIWGGIYGSFFGYELPFHLISTTSDVMIILVVSVVFGFITVFAGLLA
                     SGLQKVRMKKYAEAYNSGFVWCVILLGLLFIAVGMLMPDMRLLFVLGKWVSIFNAVGI
                     LVVSIIQAKSLSGIGAGLFNLYNISSYIGDLVSFTRLMALGLSGASIASAFNLIVGLF
                     PGTLAKLTIGLVLFILLHAINIFLSLLSGYVHGARLIFVEFFGKFYEGGGKPFQPLKA
                     SEKYIKVITKN"
     gene            1054..1530
                     /locus_tag="VQU19_001928"
     CDS             1054..1530
                     /locus_tag="VQU19_001928"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HET2481123.1"
                     /translation="MEHLATYFSTYGGAFFAALGIVLAVGLSGMGSAYGVGKAGQSAA
                     ALLKEQPEKFASALILQLLPGTQGLYGFVIGILIWLQLTPELPLEKGVAYFFVALPIA
                     IVGYFSAKHQGNVAVAGMQILAKRPKEFMKGAILAAMVETYAILAFVVSFILTLRV"
     gene            1564..2145
                     /locus_tag="VQU19_001929"
     CDS             1564..2145
                     /locus_tag="VQU19_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2481124.1"
                     /translation="MSNLENLRESVIEQAHEKGRMKLLDSKKKIDDEFEMQKSVIVKK
                     KEVEHERKLKELQQKYQIIFQQLKNKERQSTLVSKQKILKELFQSALIEMESWSADKE
                     MEFIYRILERYSQQEVIVTFGERTLAKFNLEQLEKLKFSFPNHLFSEQPISNESGLLI
                     SIGKIDDNYLYKTLIGSISKEESSSIANQIFIN"
     gene            2210..3217
                     /locus_tag="VQU19_001930"
     CDS             2210..3217
                     /locus_tag="VQU19_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HET2481125.1"
                     /translation="MDTNLFSKINTTISVKENDFITEDKFQKIIQSKDTETMAFILEA
                     TPYHLSIDVLENPSQTETSLMTKLVNDYRWAYAESPSNKIVTLFALRYVYHNIKVLLK
                     SKAAIKKDFSKLLIPIGIFDIESLKHLVSSLHSDTLPDFMVHEVESIWNEYETFNNIR
                     VLDVGADLAYFKHLKLLSNELDEVLSQVIVAMIDFYNIITVKRGLSQNKSHGDILQLL
                     SDEGSISAKEFIYIVENQEIFVWFNKINPSLDSIFSTYELKMQDATISSSELEFLCDL
                     LLYKILDQGRYNVDGPLVLARYLLGCEFEVKNLRMIISALQNTIPFGSIKERIRPHYG
                     S"
     gene            3207..3527
                     /locus_tag="VQU19_001931"
     CDS             3207..3527
                     /locus_tag="VQU19_001931"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HET2481126.1"
                     /translation="MEANKYKIGIIGSRDIILPFSMIGFDIFPAYQEQEAINTLRKLA
                     QSDYGVIYITEDIASMILDTIRHYDSQVVPAIILLPTHKQGLNLGLKRIEDNVEKAVG
                     HNIL"
     gene            3590..5365
                     /locus_tag="VQU19_001932"
     CDS             3590..5365
                     /locus_tag="VQU19_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HET2481127.1"
                     /translation="MTQGKIIKVSGPLVIASGMQEANIQDICRVGKLGLIGEIIEMRR
                     DQASIQVYEETSGLGPGEPVVTTGEPLSVELGPGLISQMFDGIQRPLDRFKLATHNDF
                     LVRGVEVPSLDRDIKWHFDSTIAIGQKVSTGDILGTVKETEVVNHKIMVPYGVSGEVV
                     SIASGDFTIDEVVYEIKKLDGSFYKGTLMQKWPVRKARPVSKRLIPEEPLITGQRVID
                     TFFPVTKGGAAAVPGPFGAGKTVVQHQVAKFSNVDIVIYVGCGERGNEMTDVLNEFPE
                     LIDPNTGQSIMQRTVLIANTSNMPVAAREASIYTGITMAEYFRDMGYSVAIMADSTSR
                     WAEALREMSGRLEEMPGDEGYPAYLGSRIAEYYERAGRSQVLGIPEREGTITAIGAVS
                     PPGGDISEPVTQNTLRIVKVFWGLDAPLAQRRHFPAINWLTSYSLYKDSVGIYIDGKE
                     KTDWNSKITRAMNYLQRESSLEEIVRLVGIDSLSDNERLTMEIAKQIREDYLQQNAFD
                     SVDTFTSFAKQEAMLSNILTFADQANHALELGSYFTEIMEGTVAVRDRMARSKYVSED
                     RLDEIKIISNEITHQIHLILETGGL"
     gene            5366..6751
                     /locus_tag="VQU19_001933"
     CDS             5366..6751
                     /locus_tag="VQU19_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000111247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HET2481128.1"
                     /translation="MSVIKEYRTASEVVGPLMIVEQVNNVSYNELVEIQLHNGEIRRG
                     QVLEIHEDKAMVQLFEGSSGINLEKSKIRFAGHALELAVSEDMVGRIFNGMGKPIDGG
                     PDLIPEKYLDIDGQAINPVSRDYPDEFIQTGISSIDHLNTLVRGQKLPVFSGSGLPHN
                     ELAAQIARQATVLNSDENFAVVFAAMGITFEEAEFFMEELRKTGAIDRSVLFMNLAND
                     PAIERIATPRIALTAAEYLAFEKDMHVLVIMTDMTNYCEALREVSAARREVPGRRGYP
                     GYLYTNLSTLYERAGRLVGKKGSVTQIPILTMPEDDITHPIPDLTGYITEGQIILSHE
                     LYNQGYRPPINVLSSLSRLKDKGSGEGKTRGDHAPTMNQLFAAYAQGKKVEELAVVLG
                     ESALSDVDKLYVRFTKRFEEEYINQGFYKNRNIEDTLNLGWELLSILPRTELKRIKDD
                     LLDKYLPLVEV"
     gene            6774..7385
                     /locus_tag="VQU19_001934"
     CDS             6774..7385
                     /locus_tag="VQU19_001934"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000251933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HET2481129.1"
                     /translation="MVRLNVKPTRMELNNLKERLKTAERGHKLLKDKRDELMRRFISL
                     IRENNRLRKEVESYLIDNLKSFAVAKSLKNSLMVEELFSIPSKEIELFIEKENIMSVT
                     VPRMHMNITSQNENSEYSYLSSNSEMDDVFATMNSLIDKLLRLAEVEKTCQLMADEIE
                     KTRRRVNGLEYSIIPNLSETIHYIELKLEEAERANLVRIMKVK"
BASE COUNT         2458 a         1042 c         1525 g         2464 t
ORIGIN      
        1 ataaaagtta tggatgagcg ttttggacat tctatttata tttatgaatc ggaaacattg
       61 tcggataatc aagatgaaat acctatcaaa ttaacgaatc attctttaat tgaaccattt
      121 gaattattga cagaaatgta tgctctgccc aaatattatg agaaagatcc tacacctgta
      181 ttagcaccat tttactttac attttttgga atgatggttg ctgatttagg ctatggttta
      241 ctattgtttt taggaacaat gttagcatta aaaatttttc atctaccttc agaaactaag
      301 agatttttaa aattctttaa tatattaggg gtagccgttg caatttgggg tggaatctat
      361 ggctcatttt ttggatatga gttgccattt catctgatat ctacaacctc tgatgtcatg
      421 attatattag tagtgtcagt tgtgtttggg tttattacag tatttgcagg tttgttagct
      481 tcaggactac aaaaagtaag aatgaagaaa tatgcagaag catataattc aggatttgtg
      541 tggtgtgtta ttctgcttgg cttgttattt attgctgtcg gaatgttgat gcctgatatg
      601 agactgttat ttgtattagg gaaatgggta tctattttta atgctgtggg aattttggtt
      661 gtttctatta ttcaagccaa aagcttgtca ggtattggag caggattgtt taatctatat
      721 aacatttcat cttatatagg tgatttagtt agtttcactc gattgatggc attaggatta
      781 tctggagcaa gtatagcatc agctttcaat ttaattgttg gtttgtttcc gggaacattg
      841 gctaaactaa caattggatt agtattattc attcttttac atgcgatcaa tatttttcta
      901 tcgttactat caggatatgt tcatggagca cgtctgatat ttgttgaatt ttttggtaag
      961 ttttatgagg gtggaggaaa accatttcaa cctttgaagg cttctgagaa atatattaag
     1021 gttattacaa agaattaatg gaggatatat ataatggaac atttagcaac ttatttttca
     1081 acctatggag gagctttctt cgctgcattg ggaattgtat tggcggttgg attaagtggt
     1141 atggggtctg cttatggagt tggtaaggct gggcaatctg ccgcagcttt actgaaagaa
     1201 cagccagaaa agtttgcctc tgctttgata ttgcaattac tgcccggaac acaaggatta
     1261 tatggttttg ttattggaat tttgatttgg ttgcaattaa ctccagaact tcctttagaa
     1321 aaaggcgttg cttatttctt tgtagctctt ccaattgcta ttgtaggata cttttcggct
     1381 aagcatcaag gaaatgtagc agtagcggga atgcaaatct tggctaaaag accaaaagaa
     1441 ttcatgaagg gagcaatttt ggctgccatg gtagaaacct atgcaattct tgcctttgtc
     1501 gtatcattca ttttgaccct tcgtgtataa gaaattaatt tgctattcaa aggaggtgtc
     1561 taaatgagca atttagaaaa cttacgagag tctgttattg aacaagctca tgaaaaaggg
     1621 cgtatgaaat tattggattc caaaaagaag attgatgatg aatttgaaat gcaaaagtcg
     1681 gtcattgtaa agaaaaaaga agtggaacat gaacgaaagt taaaagaatt acaacagaaa
     1741 tatcaaataa tttttcaaca attaaaaaat aaggaacgcc aatcaacgtt agtatcaaaa
     1801 cagaaaatat taaaagaact ttttcaatct gctttaatag aaatggaatc ttggagtgca
     1861 gataaagaaa tggagttcat ctatcgaatt ctggaacgat attcacaaca agaggtcata
     1921 gtaacttttg gggagcggac tttagctaaa ttcaatctgg aacaattaga gaaattgaaa
     1981 ttctcttttc caaatcattt atttagtgaa cagcctatct caaatgaatc aggcttactt
     2041 atttcaatag gtaaaattga tgataactat ttgtataaaa cattaattgg atcgatttct
     2101 aaggaagaaa gttcaagtat cgcaaatcaa atttttatca attaaggatg aaattggtta
     2161 atccttctta gaaatttgga gtattccaat aaaattagaa aggtatttta tggatactaa
     2221 tcttttttca aaaataaata cgacgatttc ggtaaaagaa aacgatttta ttacagaaga
     2281 taaatttcaa aaaattatac aatccaaaga tacggagaca atggcattta tcttagaagc
     2341 aactccctat catttatcga ttgacgtttt agaaaatcct agtcagacag agacttcgct
     2401 aatgacaaaa ttagtcaatg attatagatg ggcctatgct gaaagtccgt ctaataaaat
     2461 tgtgacttta tttgctttac gatatgttta tcataatatc aaagttttat taaaatctaa
     2521 ggcggcaatt aagaaagatt tttctaaatt attaattcca atagggattt ttgatataga
     2581 aagtttaaaa catttagttt cttccttaca ttcagataca cttcctgatt ttatggttca
     2641 tgaagtagaa tcaatttgga atgagtatga aacttttaat aatattcgtg tacttgatgt
     2701 cggagctgat ctagcatatt ttaaacatct gaaactttta tctaatgagt tagatgaggt
     2761 gctgtctcag gttattgtcg caatgattga cttttataat attattactg taaaacgtgg
     2821 tttatctcaa aataagagtc atggggatat tttacaatta ctttcagatg aaggaagtat
     2881 ttctgctaaa gaatttatat acattgtaga aaatcaagaa atatttgtgt ggttcaataa
     2941 aataaatcca agcttagatt caatcttttc aacttatgaa ttgaagatgc aggacgcaac
     3001 aatttcatct tctgagttag aatttttatg tgatttatta ttgtataaaa ttttagatca
     3061 aggaaggtac aatgtagatg ggccgttagt acttgctaga tatttattgg gatgtgagtt
     3121 tgaagtaaag aatctcagaa tgattatatc agctcttcaa aatacaattc cctttggatc
     3181 aataaaagaa aggatacgcc cgcattatgg aagctaataa gtataaaatt ggcataattg
     3241 gtagccgtga tattatttta ccctttagca tgattgggtt tgatatattt cctgcctatc
     3301 aagaacaaga agctataaat actctaagaa aattagccca atctgattat ggtgtcattt
     3361 atatcactga agacattgct tcaatgatat tagatacaat tcgccattat gattctcaag
     3421 ttgtgcctgc tattatttta ttaccgactc ataaacaagg tttaaattta ggattaaaac
     3481 gtatagagga taatgtggag aaagcagtag gacacaatat tttataataa tgtacaaaat
     3541 tgtctgtaat attattctat aatttttgga cttagtaagg agaataactt tgactcaagg
     3601 gaagattata aaagtatcgg gacctctagt tattgcatca ggtatgcagg aggctaatat
     3661 tcaagatatt tgccgtgtag gtaagctagg gttaatcggt gaaattattg aaatgagaag
     3721 agatcaggca tctatccaag tctatgagga aacatctggt cttggtccgg gagaacctgt
     3781 tgttacaact ggagaacctc tctcggttga attaggacca ggattgattt ctcaaatgtt
     3841 tgatggcata caacgcccat tagatcgatt taaattggct actcataatg attttctagt
     3901 tcgtggggta gaagttccaa gtttggatag agatattaag tggcattttg attccactat
     3961 agcaattggt caaaaagtga gtacgggtga tattctagga actgtcaagg aaaccgaggt
     4021 agttaatcat aaaattatgg ttccttatgg agtatctggc gaagtcgttt ctatcgcatc
     4081 tggcgatttt acaattgatg aagttgtata tgaaataaaa aaattggacg gtagtttcta
     4141 taaaggaacg cttatgcaaa aatggcctgt tcgcaaggcg cgtcctgttt ctaaacgttt
     4201 aatcccagaa gaaccattaa tcacaggtca acgagttatt gatacattct ttccagtaac
     4261 caaaggggga gcagcagctg ttcctggacc gtttggagca ggaaagacag ttgtacaaca
     4321 ccaagtagct aaattttcca atgttgatat tgttatttat gtcggttgtg gagaacgtgg
     4381 aaatgaaatg acggatgtac tgaatgagtt tcctgagttg attgacccta ataccggaca
     4441 atcaattatg caacggacag ttctgattgc taatacttca aatatgcctg ttgctgctcg
     4501 tgaggcttca atttatacag gaattaccat ggctgagtat tttcgtgata tgggctactc
     4561 tgtcgccatt atggctgatt cgacttcacg ttgggcagaa gcactacgtg aaatgtcagg
     4621 acgtctagaa gaaatgcctg gtgatgaggg ttatcctgct tatctgggaa gtcgtatcgc
     4681 tgaatattat gaaagagcgg gacgttctca ggttctaggg attccagaac gtgaaggaac
     4741 tattactgct attggagctg tatcgccacc cggtggagat atttcagaac cagttactca
     4801 aaacacttta cggattgtga aagttttttg ggggcttgat gctccgttgg cacagagacg
     4861 tcattttcct gcaattaact ggcttacatc ttattcactc tataaagaca gtgtgggaat
     4921 ttatatagat ggtaaagaga agacagattg gaatagtaaa ataactcgtg cgatgaacta
     4981 cttacaacgg gaatctagtt tagaggaaat tgttcgtctt gttggaattg attctctgtc
     5041 tgataatgaa cgactaacga tggaaattgc taaacaaatt cgagaagatt atttgcaaca
     5101 gaatgctttt gattcagtag atacattcac ttcgtttgca aaacaagaag caatgctaag
     5161 taatatccta acttttgctg atcaggcaaa tcatgcttta gagttaggtt cttactttac
     5221 agagattatg gaaggtaccg tggcagttcg agaccgtatg gcgcgaagta aatatgtttc
     5281 agaagataga ttagatgaaa tcaaaattat ttcaaatgag attacacatc aaattcattt
     5341 gatattagaa acaggaggtc tataaatgag tgttataaaa gaatacagaa ctgctagtga
     5401 agttgttggg cctcttatga ttgttgaaca agtaaataat gtgtcttaca atgagttagt
     5461 tgaaattcaa cttcataatg gagaaattcg tcgtggacaa gttttagaga ttcacgaaga
     5521 taaagcaatg gttcaacttt ttgaaggatc tagtggaata aatttagaaa agtctaaaat
     5581 tcgttttgct ggtcatgcac tagaattggc tgtatctgag gatatggttg gtcgtatttt
     5641 taatgggatg ggaaaaccaa ttgatggtgg accagattta attccagaga aatatttaga
     5701 tattgatggt caagctatta atcctgtatc tagagattat ccagatgaat ttattcagac
     5761 agggatctcc tctattgatc atttgaatac tcttgtacgt ggtcaaaaat taccagtatt
     5821 ttcaggttcg ggcttacctc ataatgaatt agcagctcag atagcaagac aagcgactgt
     5881 tttaaattct gatgaaaatt ttgcggttgt atttgcagca atgggtatta cttttgaaga
     5941 agctgagttt tttatggaag aactcagaaa aacaggagcg atcgatcgtt cagtcttatt
     6001 tatgaacttg gcaaatgatc ctgcaattga gcgtattgca actccccgca ttgctttaac
     6061 cgcggcagag tatctagctt ttgaaaaaga tatgcacgtt ctagttatca tgacggatat
     6121 gactaactat tgtgaagcgt tacgtgaagt ctcggcagcg cgccgtgaag ttccaggtag
     6181 acgaggctat ccgggatatt tatatacaaa tttatcaact ctatatgaaa gggctggtcg
     6241 cttagttggt aaaaaaggtt cagtgacaca gattcctatt ttaacaatgc cagaagatga
     6301 cataacacat ccaattcctg atttaactgg atacattact gaagggcaaa ttattttgtc
     6361 tcatgagttg tataatcaag gttatcgtcc accaatcaat gttttatctt ctctctctcg
     6421 attaaaagat aagggatctg gagaaggtaa aactcgtgga gatcatgctc caactatgaa
     6481 tcaactgttt gcagcctatg cccaagggaa aaaggttgaa gagttagcag tagtattagg
     6541 agaatcggct ttatctgatg tagataaatt gtatgtgaga tttacaaagc gttttgaaga
     6601 agagtacatc aaccaaggat tttataaaaa tcgaaatata gaagatacgt tgaatcttgg
     6661 gtgggaatta ctatcaattc ttcctagaac agagttaaaa cgtatcaaag atgatttgct
     6721 tgataaatat ttacctttgg tagaagttta atccagaaat ggagtgatta tctatggtac
     6781 gtttgaatgt aaaaccaact cgtatggaat tgaataactt aaaggaacgt ttgaaaacag
     6841 ctgaacgtgg acataagtta ttaaaggata aaagagatga attgatgagg cgatttattt
     6901 ctttgattcg tgagaataat cgacttcgga aagaagtaga aagttatcta attgataatc
     6961 taaaatcttt tgcagttgct aaatcattaa agaactctct aatggtggag gaattatttt
     7021 caattccatc gaaagaaatt gaattattta ttgagaaaga aaatatcatg agtgtaacag
     7081 ttcctagaat gcatatgaat attacttctc aaaatgagaa cagtgaatac agctatttat
     7141 cttctaatag tgaaatggat gatgtatttg ctacaatgaa tagtttaatt gataaattac
     7201 taagactggc agaagttgaa aaaacgtgtc agttaatggc tgatgaaata gaaaaaacac
     7261 gtagacgtgt aaatggttta gaatattcga ttattccaaa cttgtcggaa actattcatt
     7321 atatagaatt gaaactagag gaggcagaaa gagccaattt agttcgtatt atgaaagtga
     7381 agtagttcct ttatttagat ttttaattag atgaacaaat atcagcttgg ataaggcggt
     7441 aagcctttct aagctttttt aggctctttg tcaactgtag tgggttgaa
//
LOCUS       DAVBCA010000080         7220 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.080, whole genome shotgun sequence.
ACCESSION   DAVBCA010000080 DAVBCA010000000
VERSION     DAVBCA010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7220)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7220)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7220
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.080"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            231..645
                     /locus_tag="VQU19_001935"
                     /pseudo
     CDS             231..645
                     /locus_tag="VQU19_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720030.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(684..1127)
                     /locus_tag="VQU19_001936"
     CDS             complement(684..1127)
                     /locus_tag="VQU19_001936"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HET2481130.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(1157..3379)
                     /locus_tag="VQU19_001937"
     CDS             complement(1157..3379)
                     /locus_tag="VQU19_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HET2481131.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRMIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            3790..4032
                     /locus_tag="VQU19_001938"
     CDS             3790..4032
                     /locus_tag="VQU19_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2481132.1"
                     /translation="MTRFEEIFEEYKNPQDTFFYPLVYKENTYEKTAISIFALLMLGV
                     CCLFLFSQQSYKKLVQYYANDQNLPSRITYSEYSDK"
     gene            4372..5001
                     /locus_tag="VQU19_001939"
     CDS             4372..5001
                     /locus_tag="VQU19_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HET2481133.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            complement(5124..7016)
                     /gene="pepO"
                     /locus_tag="VQU19_001940"
     CDS             complement(5124..7016)
                     /gene="pepO"
                     /locus_tag="VQU19_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HET2481134.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
BASE COUNT         1985 a         1681 c         1378 g         2176 t
ORIGIN      
        1 ttatcatttt atgacaaaca tactatcgtt aaatgctgat ttaatcgaaa ttttgagtta
       61 taaactcctc agtttcgaac tcaaaattag ccgtgcagga taggataccc ttcataaact
      121 tatataacta ctttaatacc ttaaaaagct aataaaataa ggaatatcta agcaatatac
      181 attctaaaat acctgtacgg gagtgtctct aaagaaaagg aggttttagc atgaaaaaaa
      241 tcatcttcat caaaaccatt caactccttg tcattgatgg aatcatgctg gcatttttga
      301 catttaaaag gggggcttac ttgggactgg attttgattt atagtggttg gctcattttc
      361 tttcatcctg tgctattgac ctatctttca aaccaacttt gtgaccactt tagtcaactc
      421 tattcccaga ttagaccgag attctggcgt tttgctttac aaattctcct atgggatagc
      481 ctgatgattc tctccttggt gtctttaagt gatattccac ttttccttca gggaactctc
      541 ctcatcctag gacatctcat cccttcctat cgcatctgcc aaagcctgaa aagagacttc
      601 ccccaagcat atcaagaacc gatttctttt tggagtattt tatgatcgat gagaaagacc
      661 aagccgactg ggcttggtct ttcttatctc tttttagtat ctaggataat ggtaacaggt
      721 ccgttattaa ccagctcaac ctgcatatct gctccaaaga tacctgtctg aacgggcact
      781 tcttgcgcta atttttgatt gaaagcatca tagaagtctg atgccatatc aggtttagct
      841 gcccctgtaa aggctggacg attgcctttc ttagtatccg caaagagggt aaactgagaa
      901 atagagagga tttctccttc aatatctttg acagacaggt tcatcttgcc ttctgcgtct
      961 gaaaaaatcc gcatattgac cagttttctc acagcatagt ccaaatcttc ctcttggtcc
     1021 tctggtccaa caccaaccag caataaaagt ccctgattga tttttccctg aatctggcct
     1081 tctatactca cttgggcttt tttaacccgt tggataatga ttttcataat agcctttcta
     1141 gtaagagcta ggacaactag ccgttggtcc gtttgacaga gtaaacttct ggcacactct
     1201 taattttatc gacaaccgtg gtcagtgtag agaggttggc aataccgaag gacacatgga
     1261 tattagcaaa cttcatatcc ttggttggtt gggcattgac cgttgaaata ttcttggttg
     1321 tatttgaaag aacttgcagt acatcgttca acagtcctgt acggttgaga ccgtagatat
     1381 cgatatgggc catatactcc ttatttgagc tagagtactg gtcttcccat tccacatcaa
     1441 ggagacgttg ctcgtagttt tcttgggcac gcaggttcat acagtccaca cggtgaatag
     1501 ccacaccacg acccttggta atgtagccaa caatatcgtc accaggcacg gggttacaac
     1561 acttagcaat ccgcactagg agaccagaag caccttcaat aaccactccc ccctcatgct
     1621 tgaccttgag agtttcttta ttttcaacct tgacctcgcc acctttgaca agctcctctg
     1681 cctcagcctt ggccttggca cgctcttcct cacggcgttc cttttcagtc agacggttaa
     1741 agacggtaat cgcaccgatt tccccaaaac caatggccgc aaagagggag tcttctgtct
     1801 tgtaactggt cttttgcaga acttgatcca tgtggcgctt gtccataaat ttatttgcca
     1861 catagccatt ttcttggaac tgagccatca gcatctcacg acccttgttg acagacaatt
     1921 ccttatcttg gtttttaaag aactggcgaa tcttattgcg cgccttgcta gtcttgacca
     1981 tattgagcca gtcacggcta ggtccaaagg agttcgggtt ggcgataatt tcaacctgat
     2041 cccctgtctt taacttggtt gtcagtggaa ccatgcggcc attgaccttg gcaccagttg
     2101 ctttttcacc gaccttggta tggatttcgt aggcaaaatc aatcggtcct gaatctttgg
     2161 gaagagaacg gacagctcca tctggggtaa aaacgtaaat ctcctcagcc agatagtttt
     2221 ccttaacaga gtccacaaat tccttagcat catcagcctg gtcttggagc tccatcatct
     2281 ccttgatcca gttcattcca atagctgatt ccttgctgtt aacttgcccc tttatacctt
     2341 tcttataagc ccagtgagcc gcaaccccgt actcagccac ctcgtgcatt tccttggttc
     2401 gaatctggaa ttcaatcggc ccttttggtc cataaacagt cgtatggata gactgataac
     2461 cattagcctt gcggttggca atatagtctt tgaagcgacc tggcatcggt ttccaaaatt
     2521 catgcacgta accaagcatg gcataaacat cactttgggt atctaaaata caacgaatag
     2581 caatcagatc atagatttcc tcaaaccgtt ttctcttgtc ctgcattttg cggaaaattg
     2641 agtaaatatg cttgggacga ccataaatct tccctttcaa gtgacgttct gtcgtatact
     2701 cctctaattt tgtgactacc tcatccacca aggcctcacg ctccctgcgc ttttccttca
     2761 tcatatgggt aatcttgtaa aactccgttg gattgagata acggaaagac aagtcttcta
     2821 attcccattt gacactggaa atccccaaac gatgggcaag cggggcatag atttccatgg
     2881 tttctttgga aatacgctcc tgcttgtctt ttcgaagatg tttcagggtc cgcatattgt
     2941 gcaagcggtc agacagtttg accaaaataa cgcggatgtc ctcagacatg gccatgagca
     3001 tcttgcgatg attttccgct aattgctcct cgatcgattt gtactcgacc ttgccaagct
     3061 tggtaactcc gtcaacaatc atccgcacat caggaccaaa ctctctttcc aaatcgtcca
     3121 aagtcgcatc tgtatcttcc accacatcat gcaagaatcc acaagctact gttacagcat
     3181 ccagctttag cttagctaaa atacctgcca cttggatagg gtgaatgata taaggctcgc
     3241 ctgatttgcg atattgacca ctgtggcatt caacagcata gaccaaggcc ttatggacaa
     3301 aatgaacatc ctcttccgtt aaatattctt tggttaaagc gacaacttct tcgcctgtta
     3361 aattcacttc tttcggcatc tctactctcc aattcttcct accattttat cactttttta
     3421 agaatatgaa aactagattg gaacagaata agaaaaaaat aattcaaaat tgcttgataa
     3481 ttctgaatta ttggcccata atatactacg aagttagatt ttaaacttag gtgatagaag
     3541 gagagataga agaacggaaa ccatattgta acccaaagac tttctgattt ccccaattcc
     3601 attgaagata cgaaagataa acggtggaac tcgtatcaca tacactggta ccttgactgg
     3661 attttggaat taatactcaa tgaaaatcaa agagcaaact aggaaactag ccacaggttg
     3721 ctcaaagcac tgctttgagg ttgtagataa gactgacaaa gtcagtcaca tatatacggc
     3781 aaggcgacgt tgacgcggtt tgaagagatt tttgaagagt ataaaaatcc tcaagatact
     3841 ttcttctatc ctttagttta taaggagaat acctatgaaa aaactgctat ttctatcttt
     3901 gctctcctaa tgttaggagt ttgctgcctg ttcctattca gccagcaaag ctataaaaaa
     3961 ctcgttcaat actatgctaa cgaccagaac ctgcccagta ggataactta tagtgaatat
     4021 agcgacaaat gagaagccaa ctacggtagc actctaaaca tcacgtctat caaacaagct
     4081 aatgacggag tttatgcaac ctatgaaggg caattgacac ctttccaata ttgataaatt
     4141 gataaccagc ctgtcttcat ctagtcatgc tggtttttaa gttcatttta aatccttacc
     4201 tattctccct aactgtgcta tacttaattt atactcaatg aaaatcaaag agcaaactag
     4261 aaagctagcc gcaggctgtt caaagcactg ctttgaggtt gcagataaag ttgacgcggt
     4321 ttgaagagat tttcgaagag tattagtaca ttctttgaga ttggagttag tatgaaaatc
     4381 cataaaaccg tgaatcctgt tgcctatgaa aatacctatt atctagaagg cgaaaagcac
     4441 ctcatcgtcg tcgatcctgg tagtcattgg gaagccattc gtcagacaat cgagaagatc
     4501 aacaaaccga tctgtgctat tctcttgacc cacgcccatt atgaccatat catgagtctg
     4561 gacttggttc gcgagacgtt tggcaatcct cctgtctata tcgcagagag cgaagccagc
     4621 tggctctaca ctcctgtcga taatctctcc ggtctccctc gccacgatga tatggcagat
     4681 gtggtcacaa aacctgcaga acacaccttt gtctttcacg aagaatacca actagaggaa
     4741 tttcgtttta aggttctacc gaccccaggg cactctatcg gtggtgtttc cctagtcttt
     4801 cctgatgctc acctagtctt gacgggagat gctctattcc gcgaaactat cggacggacc
     4861 gaccttccga ctggtagcat ggagcaactc cttcatagta tccagaccca actcttcacc
     4921 ctaccaaact acgatgtcta tccaggacat ggtccagcta ctactatcgc tcacgaaaag
     4981 gccttcaatc cctttttcta gcaagatgat gacaatcgaa atttaagtaa actatccagc
     5041 aaatctttct attacaaaag gcatcctatc aaggttttca cacgtgattg gatgcctttt
     5101 ttctgatgac tagatttttt gtattaccaa ataatcacgc gctcctctgg tgaacgccac
     5161 attccgtctc cttctttgac atcataggtt gtaaagaaat cgtcgaagtt tggtacttgc
     5221 acattgacac ggagtttggc tggtgcgtgc acatcgacgc tagccaaaag tttcataaat
     5281 tctggtcgac ctttcatgcg ccagatgcga ccgaagttgt agaagaactc ttctgctgag
     5341 aagtctgctt ctctcttagc tgcttcaagc gctgctgcga ttcctcccaa gtcagccacg
     5401 ttttctgata cagtcaattt accgttaatg gttgctccat aagaatcctg tccatcaaat
     5461 tggtcaatga ctttttgtgt tttctccttg aaggcagcat agtcgctctc tgtccaccaa
     5521 tccttgaggc taccattttc gtcaaaggaa gccccgttag tatcaaaggc gtgggaaatt
     5581 tcatgggcaa tcactgcccc aataccaccg tagttagcag aagatgactg atgcaagtca
     5641 tagaaaggcg cctgtaaaat ggccgctgga aagacaatca ggttcttctg aggattgtag
     5701 taggcattga ccatatgagc aggcatgccc cattccttat agtctacagg ctggttccac
     5761 ttactccaac tgtgcttgat ttccacacgc gcaaaggcta gagcattctc aaaaagactg
     5821 gcagtttcat tcactacctt atccttgtaa cgtgcaggca attcttctgg atagccaata
     5881 taaggtttga tcacattgag cttcacgata gcctgtttac aggtttctgg agtgagccag
     5941 tcattcttaa gcagacgctc cttatagaca tcaatcatgg ttgccacttt tttctccaca
     6001 tccgccttgg cttctggaga gaacttctca cgggcgtacc aaagccccag ggcttgcttg
     6061 aaaggttcct gtgctagatg ataagctgct ttgaccttat cttttgcctc tggaactcca
     6121 gaaagggcac ggctgtaggc accagacaaa acacggatat cctctgttaa atagctggtt
     6181 gaaagattga caacactcaa aatcaaggtt gctttaagga gagaccaggc ttcctcactg
     6241 taaaattgct ctgctgcttg ccagaaacgt tcctcgtcta caataacctt gtctggtaat
     6301 tgcccaataa ctgctttgaa gaagtcatcc aaaggtaggg caggcgcgaa tttcttgaaa
     6361 tcttcgtaag aatatggatg atagagttta gcatattctg aactttcttc attagagagc
     6421 accactgccg caactcggcg gtccaattca agtctttttt ctagcaagtc ttcaatttct
     6481 tcatcagaga aatcataagc cttgaggaga tttgcgctgc tttctttcca aagagtcaag
     6541 agctcttcgc gctgaggatg ttcttctgca tagtaggtcg tatctggcaa gattgtgctt
     6601 ggagcgctag cccatagaac attgattcta gcatccataa agtctggcga tacaccaaaa
     6661 ggaaggaagt ttggttttcc tgcaagctca aactctgcta gtttagctgt aaaatccgca
     6721 aaagtttcca attcttggaa ttctttaagg agtggtaaga caggtgtgat accgtcagct
     6781 tctctcttgt caaaatcacg aactaggcgg tggtatttga caaagttttc caagatagca
     6841 tcctcaggca cttcttcacc tgctaaccac ttgtctgttg tcgccagcat caggtcttca
     6901 atttcctggt ctaaatcaac aaaacctcct gtttgagact tatctgctgg gatttcagct
     6961 gtctgttgcc attctccatt gatagcatca taaaaatcat cttgataacg tgtcatcttg
     7021 ttctcgcttt catttgtatt tgcatttatc ttaacaaaaa tcactaggga atgcaattaa
     7081 taaccattta actattattt tttagctatt ataaaaaacc tttccatgat aaaacgcata
     7141 attccaagtt ttttacactt gatactatgc gttttataat ttagaaattt atcctgaaag
     7201 ttatctttag aatctatttt
//
LOCUS       DAVBCA010000081         7162 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.081, whole genome shotgun sequence.
ACCESSION   DAVBCA010000081 DAVBCA010000000
VERSION     DAVBCA010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7162)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7162)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7162
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.081"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(741..1001)
                     /locus_tag="VQU19_001941"
     CDS             complement(741..1001)
                     /locus_tag="VQU19_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2481135.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDLTRLTASLLGDEKLSAITSSSA
                     VKADIHRFVIELEPVKSTILQNDDISLDQNEIFEILKNFLDG"
     gene            complement(1060..1611)
                     /locus_tag="VQU19_001942"
     CDS             complement(1060..1611)
                     /locus_tag="VQU19_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2481136.1"
                     /translation="MPANTKVIFQEMFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIYEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNPEFPSMIELFSIL
                     PEYPLKKDGREIPLHFDQDASLSALLLDEDYYNILVHEKETIQGYSVLSNCGLYSSKI
                     SSNHVSFHLQPQNSVLSSLQLAS"
     gene            complement(1601..1798)
                     /locus_tag="VQU19_001943"
     CDS             complement(1601..1798)
                     /locus_tag="VQU19_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2481137.1"
                     /translation="MLEIWKYRPFVSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRI
                     EEESEALENMILQYLGEDDAS"
     gene            complement(1802..2386)
                     /locus_tag="VQU19_001944"
     CDS             complement(1802..2386)
                     /locus_tag="VQU19_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2481138.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMDVVLVFSKLSDSEKKQLLQARVPFVDFKG
                     NLFFPPLGLVLNANDTEIPKELTPSEQLTWIAFLLPDGDIKQIKSVSNLLYGGAYALS
                     HSTFLAETDENTSYVIWQRKFNQLSLPLSQHVLK"
     gene            complement(2794..3219)
                     /locus_tag="VQU19_001945"
     CDS             complement(2794..3219)
                     /locus_tag="VQU19_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2481139.1"
                     /translation="MTSRVFIDADCISAFLWVGTEHLLEKLYSGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVTKGSAEIVSIDIGTEEYALYRDLTRNYDSNKIIGKGEATSIFLA
                     KKHNGILGSNNLRDVKPYVEEFSLEHMTTGDILIEAFKA"
     gene            complement(3212..3706)
                     /locus_tag="VQU19_001946"
     CDS             complement(3212..3706)
                     /locus_tag="VQU19_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2481140.1"
                     /translation="MKKSSVSLILIGEGDETERKADQFASYFLIFPSSLYRMVEEIRE
                     NANRTHLEVEDIIKLGQFYGISHKAMLYRLRNDGYLDAEEIKNMDISVIETASRLGYD
                     TSLYRPLSESKKEMVLGHYIKSTEQLLENNRISQGKYEELLLDAFRYDIVYGLDEEGE
                     LSFD"
     gene            complement(3752..3958)
                     /locus_tag="VQU19_001947"
     CDS             complement(3752..3958)
                     /locus_tag="VQU19_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2481141.1"
                     /translation="MDLSNKASNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMPLGR"
     gene            complement(3945..4106)
                     /locus_tag="VQU19_001948"
     CDS             complement(3945..4106)
                     /locus_tag="VQU19_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2481142.1"
                     /translation="MNMINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            complement(4471..5427)
                     /gene="lytA"
                     /locus_tag="VQU19_001949"
     CDS             complement(4471..5427)
                     /gene="lytA"
                     /locus_tag="VQU19_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HET2481143.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPDFTVEPEGLITVK"
     gene            complement(5803..7155)
                     /locus_tag="VQU19_001950"
     CDS             complement(5803..7155)
                     /locus_tag="VQU19_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HET2481144.1"
                     /translation="MDLIHGPILPSLLSFTFPILLSNIFQQLYNTADVLIVGRFLGQE
                     SLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWILGALLSI
                     LVMLLGFLGLYHLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLRSIGDSL
                     AALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRKSVPELL
                     PQFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQTAARRI
                     MTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIFLFFASP
                     ALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPLVSSFIE
                     LIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAILATKVQS
                     "
BASE COUNT         2298 a         1486 c         1132 g         2246 t
ORIGIN      
        1 tggtttcgca ggaagtctat tatatatgca cagacatatg aaatcttttt gagacagcag
       61 ttatgatata tttatccatt cacaacatct tctgtactaa tactacaata ttggtacatt
      121 ttgattacac aatcgtttca aaaaatatga tggaagcctg agtattttat agtaattccc
      181 ttcctatcaa ctagatcaac cagttgagtg ttgaatgttg aaacacccta gcctcagcaa
      241 aggactatga tcagcatttc ctagccaata ggacgctcca aatcacctat tctaagtcca
      301 tcactagctt ggtcagtaag atacagactg caaggcgaga ctgacgtggt tgatgagatt
      361 ttggaagagt attacaatca tagattcacc agtagacttg accgcagatt taactatagt
      421 agattgaaac tagaatagta catctctgct tctaaaacat tgttagaaat cgatttgact
      481 gtcctgatca atttgtcctg ttctcgtttc atttcactat actaaaaaac cacctgaaac
      541 aaatcaagtg actagaggat aaaaacaaag actaggcaaa aagttttgaa aagcaaaaaa
      601 cgcataatat caggtcttga aaaaccttga tactatacgt ttgattgtgg gaagattgac
      661 ttcattttct cctgaaattg aagttttttc tagtttccag atatagacga attcaatata
      721 gccatctcgc tacaattatt ttaaccatcg agaaaatttt tcagaatttc aaaaatttca
      781 ttttgatcca atgaaatgtc atcattttga agaatagttg acttcacagg ctctaattct
      841 atcacaaagc ggtgtatgtc tgcttttacc gcactacttg atgttatagc cgataacttt
      901 tcatctccta gcaaggaagc tgtcaaacgg gtaaggtcat tcaaatgctt tttaatggac
      961 ttacttaaac cttgagcacc tgtagcagag cgttccctca tatccagcca agctttagcc
     1021 ttaaaaataa ttaatactca atgaaaatca aagagcaaac taggaagcta gctgcaggct
     1081 gctcaaaaca ctgttttgag gttgtagatg gaagctgacg tggtttgaag agattttcga
     1141 agagtataaa ccacaattac tcaataccga atacccctga atggtttctt tttcatgcac
     1201 caatatatta taataatctt catccaataa taaggctgat aaactagcat cttggtcaaa
     1261 atgtaaggga atttctcgac cgtccttctt taatggatat tctggtaaga tactaaatag
     1321 ttcaatcata gaaggaaact caggattagt tgttgtaaat cgaaaaagct gcgctttctc
     1381 atctttctga cttccttgat actctcccaa ttctaaaaaa tgattcaagg tagtataaaa
     1441 ttccttattt tttacttcat aaatgatgac catatcataa tcttttgttg tgcgactttt
     1501 aaatccttgc gaatccaata cgatagaggt agcagttccc ccaatcagaa cataatagtt
     1561 ctgaaaatcc gcaaacattt cttgaaaaat aactttcgta ttagctggca tcatcttctc
     1621 ccagatactg taatatcata ttttctagtg cttcactctc ttcctctata cgtgggtcat
     1681 catcatcttt taaggtcaaa taaagagaaa tcggatctac aaattgttta tcatgattat
     1741 ttttaaaatc attccaaaac tcagatacaa aaggacgata tttccatatc tctagcatct
     1801 ttcattttaa aacatgctga gaaagtggca aggataactg attgaatttt ctctgccata
     1861 tgacatagct agtattttca tccgtttcag ctaaaaaagt tgaatgcgac aaagcataag
     1921 caccaccata tagaaggtta gaaacagatt ttatctgctt tatatcgcca tctggcaata
     1981 aaaaggcaat ccacgttaat tgttcgctag gtgttaattc cttagggatt tcagtatcat
     2041 tcgcattgag tactagtccc aatggaggga agaagaggtt tcccttaaag tctacaaacg
     2101 gaactctagc ttgaagtaat tgcttttttt cactgtctga taacttcgaa aacaccaaaa
     2161 caacatccat attggctttt tcacccatag tgcgagcctg agtaacaaat gaactcaaac
     2221 tcccccttct cttttcttta atcaataaaa atgattcctt atgaaaagtc atttgagtat
     2281 actcaaacct ttttacaaaa ctgattggta aagtcaaagt cagttcctca atactgacat
     2341 caacataaaa ggattgaaaa attgacatta tctttttgac attcatgttt tttccttatt
     2401 ctatcatttt tattatattt tatcattcgg tataataaaa tataagtttt ttgataaaat
     2461 aaccaaaaac tactcgctat cccctctcac attaccctac atatcgtttg acatgcgact
     2521 gatagttcag gaaaacttca aggagaactt ttctctcatc cactatgcag gacttactat
     2581 ttcacttcta ctcctatagg ctcaatttga cacttttctt tttcgaattg ctcatatgcc
     2641 tcctgaatag tgagttcgat ttatccaaat ttatttttgt ctattttgat gaatacttcc
     2701 acgaagatag tctgaaaatg aatttgcacc aattttcctt ctctttttaa gcatattatt
     2761 ccagatatga ttgccctctt gttcagtaat aaattacgct ttaaacgctt caatcagtat
     2821 atctcctgtt gtcatatgtt ctaaagaaaa ttcttctaca tatggtttaa catctcttag
     2881 gttattactt cctaatatcc cattatgctt tttcgctaag aaaatagaag tcgcttctcc
     2941 cttaccaata atcttgttac tatcataatt tcttgttaaa tctctatata atgcgtattc
     3001 ttcagttcca atgtctatgc tcacaatctc agctgaaccc ttagttacca actggtctat
     3061 cctagatttt aaatggggaa ttgtaggtat attgatttca tcatacacct cttgtggaat
     3121 aacaatttta cccgaataga gcttttctaa aagatgttca gtgccaaccc ataaaaatgc
     3181 tgaaatacaa tctgcatcaa taaatacacg actagtcaaa cgacaactcc ccctcttcat
     3241 ctagcccata tacaatatca tatctgaaag catctagtaa cagttcctca tacttccctt
     3301 gcgaaattct gttattttct aaaagttgtt cagtcgattt aatatagtgc cctaatacca
     3361 tttccttttt actttctgac aaaggacgat ataaacttgt atcatagcct aatcttgaag
     3421 ctgtctctat aacactaata tccatatttt taatttcttc tgcatcaagg tatccatcat
     3481 ttctcaatct atataacata gctttatgac tgataccata aaactgaccc aattttataa
     3541 tatcttctac ttcaagatga gttctattgg cattttctct gatttcctca accatcctat
     3601 acagtgaaga tgggaaaatt aaaaaataag aagcaaactg atccgctttt ctttcagttt
     3661 catctccttc accaatcaag ataagactga ctgaactctt cttcacctca tcataataaa
     3721 gatgatacag tccatgtgct aaagaaaatc tttaccttcc taatggcatg tctgaattga
     3781 ctgcaatgag actgaactga gttcctttat aacagactcc gctaatattc tttccgagtc
     3841 cataaaatac cagcgtcaaa ttttctatct tttgtaccaa tttaaaaata tctatcggcg
     3901 attcaccatc agctcccaac ttttttctaa gatttgaagc tttattactt aaatccattc
     3961 gtgatattcc tttcaccttt ttccattttg gcaatcatgc tttgattcaa agacaaatac
     4021 tcagcaatct tatcttgagt aagatttgaa gatattctaa gttcttttat tctttttcca
     4081 acatcacata catttatcat attcatacac ctctcataaa aagaatagca cattcttgtc
     4141 ataatttttt aaataaaaaa attatgacaa aacaaggaag caatttattg atgctactta
     4201 aaaatctaaa attgatgata ttaaacctat ttgatgagtt cctatcaaaa atcgtatctt
     4261 caacctcaaa acagtactta aagctatccg actcggttta cattgtcaaa tttagatttt
     4321 atttgagcat aactttctag tttgcttttt gatttttgtt taatatagta acaaaaattg
     4381 aaggaaatat ctccacaaga aaacgcatac tattaagctt tttcaagacc taataatatg
     4441 cgctgttctg atttgaaaga cattccatta ttattttact gtaatcaagc cttcaggctc
     4501 tactgtgaag tctggcttgt ctgccagtgt tccgtctggt ttgaggtagt accagcctgt
     4561 tccgtccgct gactggataa aggcatttga taccatggcg ccttctttag cgtctaagta
     4621 gtaccaagtg tccttgtact tgacccagcc tgtcttcatg gcaccttctt cgttgaaata
     4681 gtaccactta tcagcgattt tcttccagcc tgtagccatt tcgcctgagt tgtcgaacca
     4741 gtaccagttg ccgtctgtgt gcttcctcca gcggtctgca agcatatagc ctgaactgtc
     4801 aaagtagtac caagtgccat tgattttctc aaacttgtct tttggataag agccgtctga
     4861 atgtacgtac cagtagccag tgtcattctt ctgccagcct gtttcaatcg tcaagccgtt
     4921 ctcaatatca tgcttaaact gctcacggct aatgccccat ttagcaagat atggataagg
     4981 gtcaacgtgg tctgagtggt tgtttggttg gttattcgtg caatactcgt gcgttttaat
     5041 tccagctaaa ctccctgtat caagcgtttt cggcaaacct gcttcatctg ctagattgcg
     5101 taagagttcg atataaaggc ggtagtccgt catgaactct tctttggttg aatggctttc
     5161 aatcagttca accgctgcat aggtctcagc attccaaccg cccccaacgt cccaggcacc
     5221 attatcaaca ggtcctacct gcatgatgca accgttccca acaatgtgcg agaaaaaacc
     5281 taattctggg tctttccgcc agtgataatc cgcttcattc tgtacggttg aatgcggatt
     5341 cccagttgag tgtgcgtgta cttgcctata tggttgcacg ccgacttgag gcaaatctgt
     5401 tcttaattta ctcacattaa tttccatatt ctactcctta tcaattaaaa caactcattt
     5461 tttacaatcc agaaccagaa actcctttat ttctacctta caaagaagac aatcttagtc
     5521 acgattaagc ttgtagatag aacctcaaaa cgcactattt tgacactgta aataggactg
     5581 acaaggtctg cattctatct acaataacac cccagactaa aaagcttttc aaaagtatat
     5641 ttttacagtc tctatatgtc cttttcataa atactatact ttattatatc acataaaaga
     5701 agtcaaaagt ctgttaaact attttcaaca ccaaactaaa gaagagaaca caagtttttt
     5761 cgatgttcac tagaggaaat ggattttatt cagtaaatcc aactaggatt gcactttggt
     5821 tgccaaaatt gcctttcctt cttttatcaa gggatgacgg aatagtgaga agtacagttg
     5881 aactgtcatg gcaacccaga taagaggttc acaaaggata acacccttat atcctgccca
     5941 aggaataatc aaaaccacaa aaacgatttt tccgattagt tcaataaagc tagaaactag
     6001 aggaaggatc ttctgcccca agccctgcaa gcaattgcga taaatcaaca agaggctcaa
     6061 aatgggataa aaggctgaac tgatttgcag atagagactt ccattttcta tcaagtaacc
     6121 atctgtcgaa ctagccaaga aggaaaccaa ggctggactg gcaaaaaaga ggaaaataca
     6181 aacaaaaact gcccaggata tacttaaacg actgccgatt cgaagacctt gaacaatgcg
     6241 gtcaggtcgc ttagctccta gattctgaga agcaaaggtc gtcattgatg cagaaatagc
     6301 ggtcatagga agaagggcaa aggtcataat gcgtcgagct gccgtctggg cactaataat
     6361 cactgcacca aatgtattaa cagaaaactg taaaatcaca ctgccgatag atacaattga
     6421 actcatcaag cccatagcca aaccttgctc caagagatcc gcgtacaagc ttttgtccca
     6481 tttgaaatgt ttaaactgtg gcaagagttc tggcacactt ttacgaatat aataaaagca
     6541 gagaaccgct gataaacctt gcgaaataat ggtagcaagt cctgcggatt gaactcccag
     6601 atgcaattgc gtaataaaat agagatccag aaccacatta accaaggcag agaaaatcag
     6661 aaatcccagg gctgctagac tgtcaccaat agaccgcaac aagcctgcaa aaagattata
     6721 agcaaagctg acacctacac aggtcacaat catagaaata tattgataag attgaggaag
     6781 aatttctgca ggagtatcta agtattgcaa gagatgatac aagccaagaa agcccagcaa
     6841 cataactaga atgctcaaaa gagcacctaa aatccaagta gctgctactg cttccttgat
     6901 tttagtgaaa ttccgagccc cataataacg agcaatgaca atccccatgc cattgccaac
     6961 accaagtgta aaacctacaa tcaggtcaaa aatcgctgtc gtcgctccta ctgcagccaa
     7021 ggattcttga ccaagaaatc gtccaacaat caagacatca gcagtgttat agagctgttg
     7081 aaaaatattt gatagcaaaa ttggaaaggt gaagcttaag agcgagggaa gaatcggacc
     7141 atgtatcagg tccactgttc gt
//
LOCUS       DAVBCA010000082         7091 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.082, whole genome shotgun sequence.
ACCESSION   DAVBCA010000082 DAVBCA010000000
VERSION     DAVBCA010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7091)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7091)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7091
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.082"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(394..2085)
                     /locus_tag="VQU19_001951"
     CDS             complement(394..2085)
                     /locus_tag="VQU19_001951"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HET2481145.1"
                     /translation="MNTKELIASELASIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            2221..2667
                     /gene="argR"
                     /locus_tag="VQU19_001952"
     CDS             2221..2667
                     /gene="argR"
                     /locus_tag="VQU19_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET2481146.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            2718..5252
                     /gene="mutS"
                     /locus_tag="VQU19_001953"
     CDS             2718..5252
                     /gene="mutS"
                     /locus_tag="VQU19_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HET2481147.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKLDSQNNFLVAIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSCQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPALAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLITGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTENPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            5399..>7091
                     /locus_tag="VQU19_001954"
     CDS             5399..>7091
                     /locus_tag="VQU19_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2481148.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLGALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDVPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQEGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
BASE COUNT         1923 a         1381 c         1683 g         2104 t
ORIGIN      
        1 cttcggatta cgaatgaatt tgattgctgg cattatcaat catgaactag gattctagtt
       61 ttgcaggaag tctattattt ggttaggtga attagtgaag cgtttaggca agtgtctctg
      121 gttacgacgt catggactct aaatcgatta tatttagggg tcatgactag tgaagcagtt
      181 agctagttcg catataagcg gctagcgtct aacaattagg aactttagtt ccaataactt
      241 taagattacg acgttttagg acataaatcg atcatattta tgtcctaaaa ctagtgaagt
      301 atgtcctaaa actagtgaag cgcctagcca aagtccgaat aggatttggc gttagttact
      361 tagattgctt tgcaatcaag taactttggc gatttacatc ttctctggcg cttctactcc
      421 aagcaagcga agggcttctt tgagaacgac tgcggttgcg tagctgaggg ctagacggct
      481 gtcgcgttct gggctttcat ccaagatacg tgtatgtgca tagtatttgt taaaggattg
      541 agccaggcta attgcaaatt tagcaatgat agaaggttca aagttatctg ccgcacggtt
      601 gataatacgt gggaagtctt gaatgagttt aatgatttcc cagctttcag tatcattcaa
      661 gctatagttg ccagctgttt ctggtttgaa atcggctttg cgtaagatag attggatacg
      721 agcgtaggca tattgaacgt aaggtccagt ttcaccctcg aaggatacca tagcctctag
      781 gtcgaagtcg tatccatttg tacggtcggt tttgaggtca tagaatttaa tggctccaac
      841 cccaacagca tgtgctactt ggtctttgtt ttctagttca ggatttttag cctcgatttg
      901 gaccttggca cggctaacag cctctgcaac agtaggctct agcaagatga cattcccttt
      961 acgagtagag agtttcttcc cttcttttgt aaccaaacca aaaggaacgt gagtaatgtc
     1021 gtcactccag tcgtagccca tctcttgcaa gacagctttg agctgtttaa agtgggcaga
     1081 ttgttcttga ccaacgacat agatagattt agcaaattgg tattcgtttt tacggtagag
     1141 ggctgcagcc aagtcacgtg tgatatagag agttgcacca tcagacttct tgatgagggc
     1201 tggatgttca attccgtatt tctcaagatt cacaacttgg gcaccttctg attcaagaag
     1261 tagtcctttt tcagaaagaa tgtctacaac tgcatccatc ttatcattgt agaaggcttc
     1321 tccgttatag ctgtcaaatt caaccttcaa ttcattgtaa aggcggttaa attccactaa
     1381 actttcatcg cggaaccatt gccaaagagc gagagcttcc tcatctccat tttcaagttt
     1441 acggaaccat tcgcgcgctt cttcatccaa gctagggtca ttttcagctt cagcgttgat
     1501 gcggacatag agtttaagga gttcatcgat tggatgagct tttacagctt cttcgtcgcc
     1561 ccattttttg taggcaacaa tcaacatccc aaattgttta ccccagtctc ccaaatggtt
     1621 gaccttgacc gtttgataac cgattttttg gaaaatatgt gacaagctat ctccgataac
     1681 agttgaacgc aggtggccaa tagaaaatgg tttagcgata ttcggactag acatgtcgat
     1741 aacaacattt tcttgtttac caatattttg gtcagcatag tgttcttttt cagtggtaac
     1801 agcttgcaat acttgagcag aaatggcaga tttatcaagg aaaaagttaa cgtaaggtcc
     1861 tgttgcgaca actttttcaa aggcttggct gttcattttt tcagccagtt cagccgcaat
     1921 catttgtggt gctttacgtt cgactttggc aagagaaaaa gcagggaaag cgatgtcacc
     1981 catttctgag tttttagggg tttccagtaa ctttaaaata gcctcttggt ccaggctatc
     2041 aatgatgcta gccaattcgc tagcaatcaa ttcttttgta ttcattaaga gctccttttt
     2101 ggacttttct actattttat cacaatttta aagaaagaag aaaaaatttt tgaaatctcc
     2161 tgtttttttg gtataatatg gttataaata tagttataaa tatgcacgca agaggatttt
     2221 atgagaaaaa gagatcgtca tcagttaata aaaaaaatga ttactgagga gaaattaagt
     2281 acacaaaaag aaattcaaga tcggttggag gcgcacaatg tttgtgtgac gcagacaacc
     2341 ttgtctcgtg atttgcgcga aatcggcttg accaaggtca agaaaaatga tatggtgtat
     2401 tatgtactag taaatgagac agaaaagatt gatttggtgg aatttttgtc tcatcattta
     2461 gaaggtgttg caagagcaga gtttaccttg gtgcttcata ccaaattggg agaagcctct
     2521 gttttggcaa atattgtaga tgtaaataag gatgaatgga ttttaggaac agttgctggt
     2581 gccaatacct tattggttat ttgtcgagat cagcacgttg ccaaactcat ggaagatcgt
     2641 ttgctagatt tgatgaaaga taagtaaggt cttgggagtt gctctcaaga cttatttttg
     2701 aaaaggagag acagaaaatg gcgatagaaa agctatcacc cggcatgcaa cagtatgtgg
     2761 atattaaaaa gcaatatcca gatgcttttt tgctctttcg gatgggtgat ttttatgaat
     2821 tattttatga ggatgcggtc aatgctgcgc agattctgga aatttcctta acgagtcgca
     2881 acaagaatgc cgacaatccg atccctatgg cgggtgttcc ctatcattct gcccaacagt
     2941 atatcgatgt cttgattgag cagggttata aggtggctat cgcagagcag atggaagatc
     3001 ctaaacaagc agttggggtt gttaaacgag aggttgttca ggtcattacg ccagggacag
     3061 tggtcgatag cagtaagctg gacagtcaga ataatttttt ggttgccata gaccgcgaag
     3121 gcaatcaatt tggcctagct tatatggatt tggtgacggg tgacttttat gtgacaggtc
     3181 ttttggattt cacgctggtt tgtggggaaa tccgtaacct caaggctcga gaagtggtgt
     3241 tgggttatga cttgtctgag gaagaagaac aaatcctcag ctgccagatg aatctggtac
     3301 tctcttatga aaaagaaagc tttgaagacc ttcatttatt ggatttgcga ttggcaacgg
     3361 tggagcaaac ggcatctagt aagctgctcc agtatgttca tcggactcag atgagggaat
     3421 tgaaccacct caaacctgtt atccgctacg aaattaagga tttcttgcag atggattatg
     3481 cgaccaaggc tagtctggat ttggttgaga atgctcgctc aggtaagaaa caaggcagtc
     3541 ttttctggct tttggatgaa accaaaacgg ctatggggat gcgtctcttg cgttcttgga
     3601 ttcatcgccc cttgattgat aaggaacgaa tcgtccaacg tcaagaagta gtgcaggtct
     3661 ttctcgacca tttctttgag cgtagtgact tgacagacag tctcaagggt gtttatgaca
     3721 ttgagcgctt ggctagtcgt gtttcttttg gcaaaaccaa tccaaaggat ctcttgcagt
     3781 tggcgactac cttgtctagt gtgccacgga ttcgtgcgat tttagaaggg atggagcaac
     3841 ctgctctagc ctatctcatc gcacaactgg atgcaatccc tgagttggag agtttgatta
     3901 gcgcagcgat tgctcctgaa gctcctcatg tgattacaga tgggggaatt atccggactg
     3961 gatttgatga gactttagac aagtatcgtt gcgttctcag agaagggact agctggattg
     4021 ctgagattga ggctaaggag cgagaaaact ctggtatcag cacgctcaag attgactaca
     4081 ataaaaagga tggctactat tttcatgtga ccaattcgca actgggaaat gtgccagccc
     4141 actttttccg caaggcgacg ctgaaaaact cagaacgctt tggaaccgaa gaattagccc
     4201 gtatcgaggg agatatgctt gaggcgcgtg agaagtcagc caacctcgaa tacgaaatat
     4261 ttatgcgcat tcgtgaagag gtcggcaagt acatccagcg tttacaagct ttagcccaag
     4321 gaattgcgac ggttgatgtc ttacagagtc tggcggttgt ggctgaaacc cagcatttga
     4381 ttcgacctga gtttggtgac gattcacaaa ttgatatccg gaaagggcgc catgctgtcg
     4441 ttgaaaaggt tatgggggct cagacctata ttccaaatac gattcagatg gcagaagata
     4501 ccagtattca actgattaca gggccaaaca tgagtgggaa gtctacctat atgcgtcagt
     4561 tagccatgac ggcggttatg gcccagctgg gttcctatgt tcctgctgaa agcgcccatt
     4621 taccgatttt tgatgcgatt tttacccgta tcggagcagc agatgacttg gtttcgggtc
     4681 agtcaacctt tatggtggag atgatggagg ccaataatgc catttcgcat gcgaccaaga
     4741 actctctcat tctctttgat gaattgggac gtggaactgc aacttatgac gggatggctc
     4801 ttgctcagtc catcatcgaa tatatccatg agcacatcgg agctaagacc ctctttgcga
     4861 cccactacca tgagttgact agtctggagt ctagtttaca acacttggtc aatgtccacg
     4921 tggcaacttt ggagcaggat gggcaggtca ccttccttca caagattgaa ccgggaccag
     4981 ctgataaatc ctacggtatc catgttgcca agattgctgg cttgccagca gaccttttag
     5041 caagggcgga taagattttg actcagctag agaatcaagg aacagagaat cctcctccca
     5101 tgagacaaac tagtgctgtc actgaacaga tttcactctt tgatagggca gaagagcatc
     5161 ctatcctagc agaattagct aaactggatg tgtataatat gacacctatg caggttatga
     5221 atgtcttagt agagttaaaa cagaaactat aaaaccaaga ctcactagtt aatctagctg
     5281 tagcaaggag acttctttga caattctcca cttttttgct agaatgacat cacacaaaca
     5341 gaatgaaaag gagctgacgc attgtcgctc ccttttgtct attttttaag gagaaagtat
     5401 gctgattcag aaaataaaaa cctacaagtg gcaggccctg gcttcgctcc tgatgacagg
     5461 cttgatggtt gctagttcac ttctgcaacc gcgttatctg caggaagtct taggcgccct
     5521 ccttactggg aaatatgaag ctatttatag tatcggggct tggttgattg gtgtggccgt
     5581 agtcggtcta gttgctggtg gactcaatgt tgtcctcgca gcctatattg cccaaggagt
     5641 ttcatccgac cttcgggagg atgccttccg taaaattcaa accttttctt atgctgatat
     5701 tgaacaattt aatgcgggaa atctagtcgt tcgaatgaca aatgatatca accagattca
     5761 gaacgttgtc atgatgacct tccagattct tttcagactt cccctcttgt tcatcggttc
     5821 gtttatccta gcggttcaaa ccttaccttc tctgtggtgg gtgattgttc tcatggtagt
     5881 cttgattttt ggtttgactg ctgtcatgat gggaatgatg gggcctcgtt ttgccaagtt
     5941 tcaaaccctt cttgagcgca tcaatgccat tgccaaggaa aatttacgtg gcgttcgtgt
     6001 ggtcaagtcc tttgtccaag aaaaagagca atttgctaag tttacagagg tctcagacga
     6061 gcttcttggt caaaaccttt acattggtta tgccttttca gtagtggaac cctttatgat
     6121 gttggttggt tacggggcgg tcttcctctc tatttggctg gtcgcgggaa tggttcagtc
     6181 ggatccgtct gttgttggtt ccatcgcttc ttttgttaat tacctaagcc agattatctt
     6241 taccattgtt atggttggat ttttgggaaa ttctgtcagc cgtgccatga tttccatgcg
     6301 tcgtattcga gaaattcttg acgcagagcc agctatgacc ttcaaggatg tcccagatga
     6361 agagttggtt ggaagcctta gctttgaaaa tgtgaccttt acctatccaa tggacaagga
     6421 accgatgctg aaagatgtga gctttactat tgaacctggt caaatggttg gtgtagttgg
     6481 agcgactggt gcaggaaagt caaccttggc tcaattgatt ccacgtctct ttgatccaca
     6541 ggaaggggct atcaaaatcg gaggtaagga tattcgagaa gtgagtgaag gaaccctgcg
     6601 taaaacagtt tccatcgttc tccaacgtgc cattcttttt agtggaacga ttgcagataa
     6661 cttgagacag gggaagggaa atgctactct atttgaaatg gagcgcgcag ccaatattgc
     6721 ccaggctagt gaattcattc atcgtatgga gaaaaccttt gaaagtccag ttgaagaacg
     6781 gggaaccaat ttctctggtg gacaaaaaca aaggatgtcg attgcgcgtg ggattgtcag
     6841 caatccacgt attctgattt ttgatgattc gacctcagcc ttggatgcca aatcagagcg
     6901 cttggtgcaa gaagctttga ataaggactt gaaggggacg acaaccatta ttattgctca
     6961 aaaaattagc tcggttgtcc atgcagacaa gatcttggtt ctaaatcaag gacgattgat
     7021 tggtcaaggc acgcatgcag acttggttgc caacaatgcc gtttaccgtg aaatctatga
     7081 aacacagaaa t
//
LOCUS       DAVBCA010000083         6925 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.083, whole genome shotgun sequence.
ACCESSION   DAVBCA010000083 DAVBCA010000000
VERSION     DAVBCA010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6925)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6925)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6925
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.083"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..1647
                     /locus_tag="VQU19_001955"
     CDS             <1..1647
                     /locus_tag="VQU19_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HET2481149.1"
                     /translation="NYRTDKTAMWALSGNFDASKSWKKEELELANWISKNYSINPVDN
                     DFRTTTLTLKGHTGHKPQINISGDKNHYTYTENWDENTHVYTITVNHNGMVEMSINTE
                     GTGPVPFPTPDKFNDGNLNIAYAKPTTQSSVDYNGDPNRAVDGNRNGNFNSGSVTHTR
                     ADNPSWWEVDLKKMDKVGLVKIYNRTDAETQRLSNFDVILYDNNRNEVAKKHVNNLSG
                     ESVSLDFKEKGARYIKVKLLTSGVPLSLAEVEVFRESDGKQSEEDIDKITEDKVVSTN
                     KVATQSSTNYEGVAALAVDGNKDGDYGHHSVTHTKADSNAWWQVDLGEEFTVSKVDIY
                     NRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDKVVDGLLSLKVPSVGAKLVKIELKSAA
                     IPLSLAEVEAYGSKRTPKKLSNIALTKETRQSSTDYNGFSRLAVDGNKNGDYGHHSVT
                     HTKGDSPSWWEIDLAQTEELEKLIIYNRTDAEIQRLSNFDIIIYDSNNHEVFKQHIDS
                     LESNNLSIDLKGLKGKKVRISLRNAGIPLSLAEVEVYTYK"
     gene            1704..3470
                     /locus_tag="VQU19_001956"
     CDS             1704..3470
                     /locus_tag="VQU19_001956"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HET2481150.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEANDTDIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERAMVWVKEHIKEGVDRNREDLILSKEEKEKQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGCAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELEESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDSGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            3616..4767
                     /locus_tag="VQU19_001957"
     CDS             3616..4767
                     /locus_tag="VQU19_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HET2481151.1"
                     /translation="MAIFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKTLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHRCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPQALTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIEHENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIVEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            4912..5796
                     /locus_tag="VQU19_001958"
     CDS             4912..5796
                     /locus_tag="VQU19_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HET2481152.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            6195..6446
                     /locus_tag="VQU19_001959"
     CDS             6195..6446
                     /locus_tag="VQU19_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HET2481153.1"
                     /translation="MKEFQFERKQRFSLRKYAIGACSVLLGTSLFFAGMGDQPVQDTE
                     TSSALISSHYLDEQDLSEKLKSELQWFELENKLLNLWEH"
     gene            6434..6724
                     /locus_tag="VQU19_001960"
     CDS             6434..6724
                     /locus_tag="VQU19_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2481154.1"
                     /translation="MGALGYYEGFVPYVSNQYKNQAEEEGKPLSDKYIFEKILGKTYA
                     AFKKDQINERVEKLGKLKPITINYNGKSEVIDSKEKLQELMNKAVKDEVAQI"
BASE COUNT         2283 a         1136 c         1497 g         2009 t
ORIGIN      
        1 aattacagga cagataagac agctatgtgg gcattatcag gaaattttga tgcatcaaaa
       61 agttggaaga aagaagaatt agagttagcg aactggataa gcaaaaatta ttccatcaat
      121 cctgtagata atgactttag gacaacaaca cttacattaa aagggcatac tggtcataaa
      181 cctcagataa atataagtgg cgataaaaat cattatactt atacagaaaa ttgggatgag
      241 aatacccatg tttataccat tacggttaat cataatggaa tggtagagat gtctataaat
      301 actgaaggga caggcccagt ccctttccca acaccagata aatttaatga tggtaatttg
      361 aatatagcat atgcaaaacc aacaacacaa agttctgtag attacaatgg agaccctaat
      421 agagctgtgg atggtaacag aaatggtaat tttaactctg gttcggtaac acacactagg
      481 gcagataatc cctcttggtg ggaagtcgat ttgaaaaaaa tggataaagt tgggcttgtt
      541 aaaatttata atcgcacaga tgctgagact caacgtctat ctaattttga tgtgattcta
      601 tatgacaata atagaaacga agttgctaag aaacatgtta ataatttgtc gggtgaatct
      661 gttagtctag atttcaaaga aaaaggagca aggtatatta aagttaaatt actaacgagt
      721 ggagtgcctt tgagtttagc agaagtagag gtttttagag aatcagatgg taagcaatct
      781 gaagaggata tagataaaat aacagaagat aaagtagtct ctacaaataa ggtagctact
      841 caaagttcaa ccaattatga gggtgtagct gctttagcag ttgatggtaa taaagatgga
      901 gattacggac atcattcggt gactcatact aaggcagatt ctaacgcttg gtggcaggtc
      961 gatctgggag aagagtttac ggtttctaaa gttgatattt ataatagaac agatgccgaa
     1021 cctcagcgtt tatctaattt tgatgttatt tttctatctt catcaggaga agaagttttt
     1081 agaagacatt ttgataaagt agttgatggt ttgttatctt taaaagtacc ttctgtaggg
     1141 gctaagctag tcaaaataga attaaaatca gcagctattc cgttaagttt agcggaagtt
     1201 gaagcctatg gttcaaagag aactccgaag aaactttcta atattgcatt aaccaaagaa
     1261 actcgacaga gttcaacgga ttacaatggt ttttctcgtc tagcagttga tggaaataaa
     1321 aacggagatt atggtcatca ttcagtgact cataccaaag gagattctcc ttcatggtgg
     1381 gagatagatt tagcacaaac cgaagaatta gaaaagttaa ttatttataa tagaacagat
     1441 gctgaaattc agagattatc aaattttgat attattatat atgattcaaa taatcatgaa
     1501 gtttttaaac aacatattga cagtttagaa agcaataatc tatccataga cttaaaaggg
     1561 ctgaagggaa aaaaggttag aatttctttg agaaacgcag gaattccttt aagtttggca
     1621 gaggtagagg tttatactta taagtaattt taaaaattat catcggtagt atgaaagaaa
     1681 cagaaaaata agaggaaaat agtatgattc aacatccacg tattgggatt cgtccgacta
     1741 ttgatggtcg tcgtcaaggt gtacgcgaat cacttgaagt acaaacaatg aacatggcta
     1801 aaagtgtggc agatttgatt tcaagcacat tgaaatatcc agatggggaa cctgtggaat
     1861 gtgtgatttc tccatctacc attggtcgtg ttccagaggc tgcagcttcc catgagttgt
     1921 ttaaaaaatc aaatgtttgc gcaacaatta cagttacacc atgctggtgt tatggtagtg
     1981 aaactatgga tatgtctcca gatattcctc atgctatttg gggatttaat gggacagaac
     2041 gcccaggagc tgtctatctt gcagctgtac tagcttcaca tgctcaaaaa gggattccag
     2101 cctttgggat ttatggtaga gatgttcagg aagctaatga tacagatatt ccagaagatg
     2161 tcaaagaaaa acttttacgt tatgcgcgtg cagctcttgc aactggcttg atgagagaca
     2221 ctgcttacct atcaatgggt agtgtttcga tggggattgg cggttctatt gtaaatccag
     2281 atttcttcca agaatactta ggaatgcgaa atgaatcggt agatatgacg gagttcacgc
     2341 gccgtatgga ccgtggtatt tatgacccag aagagttcga acgtgctatg gtttgggtaa
     2401 aagaacatat caaagaaggg gttgaccgaa atcgtgagga tttgattctt tctaaagaag
     2461 agaaagaaaa acaatgggaa tttgttatta agatgttcat gattggacgt gacttaatgg
     2521 ttggtaaccc aaggcttgct gaacttggtt ttgaggaaga agcggttggt caccatgctt
     2581 tagtagctgg tttccaaggt caacgtcagt ggacagacca ttttccaaat ggagatttta
     2641 tggaaacttt cctcaatact cagtttgact ggaatggtat tcgaaaacca tttgtatttg
     2701 cgacagagaa tgattcacta aatggtgtgt ctatgctctt taattatcta ttaacaaata
     2761 ctccacaaat ctttgctgat gtgcgcactt attggagtcc agaggctgtt aaacgtgtaa
     2821 cgggacatac tttagagggt tgtgctgcag ctggcttctt acatctaatc aactctggtt
     2881 cttgtacatt ggatggtaca ggtcaagcta ctcgagatgg caaacctgtt atgaaaccat
     2941 tctgggagtt ggaagaaagt gaagtacagg ctatgcttga aaatacagac ttcccaccag
     3001 caaaccgcga gtacttccgt ggaggaggat tctcaactcg tttcttgacg aagggggata
     3061 tgccagtaac aatggtacgt ctcaatcttc taaaaggggt tggtccagtg ctacaaattg
     3121 cagaaggtta cacacttgaa cttcctgaag atgttcacca tactttagat aatcgtacag
     3181 attcaggatg gccaactact tggtttgctc cacgtttgac aggaaaaggt gctttcaagt
     3241 ctgtctatga cgtcatgaat aattggggag ctaatcacgg agccataaca tatggacaca
     3301 ttggagcaga cttgattacc ttggcttcta tgttgagaat tcctgtcaat atgcataatg
     3361 tacctgagga agatatcttt agacctaaaa attggtcctt atttggaaca gaagatctag
     3421 aatcagcaga ctatcgtgca tgtcagttgt tgggaccact acataaataa aacttgttta
     3481 tataggaggt gaacttacgt ccctcctatc cttttaaaaa gatttgttaa acaattcaca
     3541 aataattgaa aacgaataca aaaagtaata taatgatgtt aaatagatag cgcggaggcg
     3601 caggaggaaa attatatggc tatattttat gttccggcag tcaaccttat tggaaaaggt
     3661 gttgtaaatg aagtgggtcc ttatatcaag gaacttggct ataaaaaggc acttttggtg
     3721 acagataagt acatcgaagg cagtgatatt ttacctaaga ctttaaaacc actggataca
     3781 gaaggaatcg aatatgtcat ctttagcgat gtagagccaa accctacttg taaaaatgtc
     3841 acagatgggg tagctgcttt gcaagaacat agatgtgatt ttatcatcag tcttggcggg
     3901 ggttctccac aggatgcagc tagttgtatt tctatcatgg ctacaaatgg tggaaaacca
     3961 caggattatg aagggcttca taagtctgct aaaaaaggct tgccggttgt ggctatcaat
     4021 acaacggcag gtacatcagc agaaatcact attaactatg tgattactga tgaagaacgc
     4081 aaggttaaga tggtaatggt tgacaagaat agccttgcct tgatttctgt caatgaccct
     4141 gaactcatgc tttccaaacc tcaagccttg actgctgcta ctggtatgga tgctctgact
     4201 cacgctgttg aagctttggt aacacctggt gcttatgatg taaccaagaa actgtctatt
     4261 ggtgctattg agcttatcaa ggaatatctt cctcgtgctg tagaaaatgg acatgatatt
     4321 gaagcgcgtg aaggtatggt caatgccatc ttccttggtg gtatgagctt taataatgct
     4381 ggtcttggtt atgttcactc aatggctcac caactcggtg cagtatataa tttgccacat
     4441 ggtgtttgct gtgccatgtt gctaccagtt atagaacatg aaaatgctaa acgtgtacca
     4501 gaagctttcc gcaatgttgc caaagccttg ggacttcatg tagaaggtaa atcagatcaa
     4561 gaatgtgccg attatgcgat tgttgagatt gagaagcttt ctgagacagt aggtattcct
     4621 aagaaactga ctgaacttgg tattgaagaa aaagatttcg actttgaata cctttctaag
     4681 aatgccttga ttgatgcctg cgcaccagga aatccattta tgccaacctt agaagaaacg
     4741 attgcctttt ataaagagtt attttagcaa gagattggac gacaatagga caattcacct
     4801 ctaattattg acatttcagg aaaaatcgca gtaaaaacgg cacagccttc tttaaatgtg
     4861 ctataatact agaaaaatac ttgtggaggt tccattatgg caatattttt catgattttt
     4921 ctgattgttt gtgtgctcct attggtgata gtcacactga gtacagttta tgtggttcgt
     4981 cagcagtcgg tggcgattat tgaacgcttt gggaaatacc aaaaggttgc taatagcggt
     5041 attcatattc gcttgccttt tgggattgac tcgattgcag cacggattca gttgcgcttg
     5101 ttgcaaagtg atattgtggt tgagactaag accaaggaca atgtgttcgt tatgatgaat
     5161 gtagcgactc agtaccgtgt caacgagcag agcgtgacag atgcttacta taaactcata
     5221 cgtccagaat ctcagattaa atcttatatc gaagatgctc ttcgctcttc tgttccaaaa
     5281 ttaaccttgg atgaattgtt tgagaaaaaa gatgagattg cccttgaagt tcaacaccaa
     5341 gtagcagaag aaatgaccac ttacggctac attatcgtga aaaccttgat taccaaagtc
     5401 gaaccggatg cagaagttaa gcaatccatg aatgaaatca atgcggcgca acgtaagcgg
     5461 gtcgcagcac aagaattggc ggaagctgac aagattaaaa ttgtcactgc agctgaagca
     5521 gaagcagaaa aagaccgcct tcatggtgtg gggattgccc aacaacgtaa ggcgattgtg
     5581 gatggattgg cagagtctat caccgaactc aaggaagcca atgttggcat gacagaagaa
     5641 caaatcatgt ctatcctctt gaccaaccag tatttggata ccttgaatac ctttgcctct
     5701 aaaggaaatc aaaccatctt tttaccaaat acgccaaatg gtgtggatga tatccgaaca
     5761 caaatcttgt cagcccttcg cgctgagaag aaataataga ctaatactct tcgaaaatct
     5821 cttcaaacca cgtcagcgtc gccttgccgt atagatgtta ctgactttgt cagttctatc
     5881 tgcaacctca aaacagtgtt ttgagctgac ttcgtcagtc ttatctacta cctcaaaacg
     5941 gtgttttgag caacctgtgg ctagtttcct agtttgctat ttgattttca ttgagtacaa
     6001 agagcttggc aacaggctct ttttgtattg cgtttattaa gaaaaacaaa aaacatagat
     6061 atacatttaa ctaaaaatta ttgtatgtta cctcccttaa ttaggaatga taagggaata
     6121 actagaaaga tttgtgaata caaactattt ctgatataca aaatatacag taataatgaa
     6181 tgatgggaga tgggatgaaa gaatttcaat ttgagagaaa gcagcgtttt tctttgagga
     6241 aatatgcaat aggagcttgt tcggtcttgc taggaacgag tttatttttt gctggtatgg
     6301 gtgatcagcc tgtacaggat acagaaacga gttcagcact aatttcaagt cattatttgg
     6361 atgagcagga tttatctgaa aagctgaaat ctgagttgca atggtttgaa ttagaaaaca
     6421 agcttttgaa cttatgggag cattaggtta ctatgaagga tttgttcctt atgtttcaaa
     6481 tcaatacaaa aaccaagctg aagaagaagg caaaccgcta tctgataaat atattttcga
     6541 aaaaatctta ggaaaaacat atgcagcctt caaaaaagat caaattaatg agcgtgtcga
     6601 gaaattaggt aagttaaaac ctattacaat aaattacaac ggaaaatcag aagtaattga
     6661 tagtaaagaa aaattacaag agcttatgaa taaagccgtt aaagacgaag tggctcaaat
     6721 atagtaaaat gaaataagaa caggacaaat cgttcaggac agtcaaatcg atttctaaaa
     6781 atgttttaga agtagaggtg tactattcta gtttcaatat actataaaat caggcaatac
     6841 cacggctaaa aagtttgagt ttatcgaaac accagtgcaa aaactgaaaa aagcgattta
     6901 taaagctcat ctcaaagatt cagat
//
LOCUS       DAVBCA010000084         6830 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.084, whole genome shotgun sequence.
ACCESSION   DAVBCA010000084 DAVBCA010000000
VERSION     DAVBCA010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6830)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6830)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6830
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.084"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(201..1625)
                     /locus_tag="VQU19_001961"
     CDS             complement(201..1625)
                     /locus_tag="VQU19_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HET2481155.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAIERAAYLHKTAAILERDKEKIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMLKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2169..4448)
                     /gene="pulA"
                     /locus_tag="VQU19_001962"
     CDS             complement(2169..4448)
                     /gene="pulA"
                     /locus_tag="VQU19_001962"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HET2481156.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKTYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGCLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4560..6518)
                     /gene="ligA"
                     /locus_tag="VQU19_001963"
     CDS             complement(4560..6518)
                     /gene="ligA"
                     /locus_tag="VQU19_001963"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HET2481157.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASQLLLQYFHSIENLSQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6611..>6830)
                     /locus_tag="VQU19_001964"
     CDS             complement(6611..>6830)
                     /locus_tag="VQU19_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET2481158.1"
                     /translation="FTQVQTKVESEFLGRVLSTIFTLAILFMPIAKGFMTVLPSVHLS
                     SFLIIGSGVIILSCISFIYVRTHFEKLI"
BASE COUNT         2020 a         1502 c         1238 g         2070 t
ORIGIN      
        1 actatatata gtaaaatgaa ataataacag gacaaatcga tcaggacagt caaatcgatt
       61 tctaacaatg ttttagaagt aaatctgtac tattctagtt tcaatatact ataataccaa
      121 aaagttcgta ttttttctat aattattatt attttatagc aaaaaataaa accaggaaaa
      181 caatttcctg attttacacg ttatttcaca tcaaaaacaa tggatttgac atttgtcatc
      241 gcttcaatgc tatatttaat tccttgcact ccagctccag aacctttgac accaaggaat
      301 gggaaattat ctggaccacg ctgggtttta ttattaatgt ggactgtacc tacttcaagt
      361 ttttcagcaa tttcaaaggc ttttttgaaa tcatttgtaa agactgatga ttgaaggccg
      421 aattcagatt cgttggcaaa ggcaatagct tcctctacac tagccacacg aatgattggt
      481 aaaacaggac caaatggctc ttcccatgcc actttcatat cttttgtaac ttggtcaaaa
      541 agcactggcc agaggagatt gccctcacgt ttgattggtg taagagcctg agcctctttt
      601 tcttgtgcat cctcaatcaa gccccaaatg aagtcggctg aagcattgtc aataacaggt
      661 gtaatatcag cattgtcaaa tggatcacca actgttaatt tagaaacttc ttcctgaagc
      721 aaagtagcta atttatctgc tacactttcg agaacaatga cacgtttaat ggccgtgcaa
      781 cgttgtcctg agtagctaaa ggctcccgca acaatttgct tggcagcatg ttccaaatct
      841 gcatcttcta gtacaagagc tgcatctttc ccaccaagtt ccaacatgat aggacgcata
      901 ccagctaaac gaccaatacg ttctccaata ggagttgaac ctgtaaagtt gatgaagttg
      961 acttctttgt gctcaatgat ataatcccca atttctgaac cacgacctgt aatggtgttg
     1021 aaaacacctg ccggaatccc tgcttcttca aatgctttag ccaacaagag tccagaaatg
     1081 gaaccttgtg ttggtggctt caacatgacc acattccctg caatcaaggc aggtgcaatt
     1141 ttagaagcag ataaattaac tggataatta aagggagcaa tcgctagcac gataccaact
     1201 ggttcacgac ggacaacagc cagtttgttt ttacttgctg cctcaaaacc accaccttcc
     1261 attgcttgtc cagtgatacg gagaccttcc tcagcagcat aacgaatcaa gtctgctgta
     1321 cgcactactt ctccaattgc tgctttaatc ccttttgcta cttctttggc aaggatagta
     1381 ccaatttttt ccttatcgcg ttctaaaata gctgctgttt tatgcaaata agccgcacgt
     1441 tcaattgctg ataaagctcg ccatgctggc agggctgcac gcgcagcttg catagcctca
     1501 tcagcttcag tctgagtcat ggctggaact gtacccaatt cttcttgatt gattggtgaa
     1561 taaatcgtaa tttcttgttc agatgatttc cattttccat ttactaaatt ctgatatctt
     1621 gtcaaattct tgtcctcctg aaaatgatta agatatattt taccaaattt tcagaaaata
     1681 acaacccttt ttgcaaaatt tttgagatta ttttcacaag cttgattttt caaagtatac
     1741 tcaataaaaa taaaaaaatc cactacgtca aggcgaggct aatgtggttt gaagaaattt
     1801 tcgaagagcg tgaatgagta tcatctatag taaaataaaa aaactgaaca atttggttgg
     1861 ggacagccaa accaatttct cacaatgttt cagaaacaag ggtgtgctat tccaatttca
     1921 gcctactata actgtcatag attgctgaaa caaagtctag gtaaaagtct tcataataaa
     1981 aagacctcct atcaaatgtt caaaaacttt gataggaggt cttgtttcgt gaaaatattt
     2041 atcaaatttt ctatacaagt gagctgttag ccaggttctt tctattcttt caatttcaat
     2101 gaatggattt tttaccaata ctcataactg ggaatttttc tgtctaaaaa tagcgagata
     2161 gatggtattt ataaaacact caagacagct agactaatat catttaaaac attatcttct
     2221 tttgagcgac tgttggttac caacatagct aaatttcctg cattttcaaa ttgatagggt
     2281 tctgatttag cattcacaac taccaagagg tgttctttgc cgtgaacttc atagataagg
     2341 cagccgctat gttcaatcgc agaatgcaca aagacatgat ggtaaatttc atcatagcta
     2401 gagtaagaaa aggcaccagt ttttgtcttc aatcggatga cttgacggat aaactcaata
     2461 ctgtcttgac gctcattaat caagttccag ttcacttggt tcacactgtc aggagcatta
     2521 tagctattca tcgcacgctc tctatcatca tgggtcaact caccattttc accagtcgca
     2581 accagtttgg tacgaccaaa ttcttgaccg atttccataa aggccatccc ctgcatgagc
     2641 agattcatgg ctgtggcagt ttcgaccttg cgcatgattt gctctgaact ttggtctgga
     2701 tgaagggttg ccaataaatc gtgaagattg taattgtcat gggcttctac atagttaagc
     2761 acctgatttg gatgtgtata gcttcctaat tcacgacttc ctaggattgc tttagctaga
     2821 attggctctg tcgcagcacc actgacaaaa cctgacttga tagcaccata aacttctccc
     2881 cctttgacag catcgcgctg attgtcatta aagaaaccaa tatttggcat ctggtaggca
     2941 ttgtccttct tggccttatc ataaggggca agacctgttc ccatatccca tccttctcca
     3001 tagaggataa tgttggagtc aatttcatcc aagctttgac gaatcatctg catggtcttg
     3061 acatcatgaa tccccatcaa gtcaaaacgg aagccgtcaa tattatattc ctgcacccag
     3121 tatagaagag aatcaatcat atacttgcga aacatttcgt gttcactggc tgtttcattt
     3181 ccaacacccg ttccattctg gaaggtacca tctggattca tacgataata gtaatcaggg
     3241 actgttgttt ggaatggtgc atcaacaact gagaaggtat ggttatagac tacatccata
     3301 atgactccaa tacccgcatc gtgataagct tgaaccatca ccttcaaatc acgaatgacc
     3361 tgagctggat catctggatt agttgaaaaa ctagtttctg gcgcgttata gttttgtgga
     3421 tcataacccc agttgtaggt tacatttcca tcctcatcgt attctttatg acggtctgca
     3481 attggttgca attgaacata attgtagccc agcttcttga tgtaatcaaa agcagttgac
     3541 tggccgtatt ggttaactgt tccagcctga gcagcaccca agaaagttcc tcgaagatgt
     3601 tcatctacac ccgatgtagg tgatttagtc aaatcacgaa tatgcatttc acagataact
     3661 gccttacatg gattttccaa gcgccaagta gcctccgaac cgtgcttaac ctcgaagttt
     3721 tcaacttgct tttctacatg gctcagaata gctgaacgtt tgccatcagg gctggtcgcg
     3781 attgtataag gatcacgtgt cagtgtttgg tgatgaggga attggacttg atactgataa
     3841 gtcttaccta ccaaatcttc ttcaacatcc aaactccaga caccgattgt attgtcctta
     3901 tgattataag agtagctatt gcctcttttc atctcaaaag tcttccaaac gggtgcatca
     3961 ttagcagctg attcataaac gacaacttgc acttctgtcg ctgtaggtga ccagagggaa
     4021 aaatgagcct gattgtcctc tacacggcaa cccaattctc cttggtaacc ccaatgatga
     4081 tcaaaactag cactgttaat ggccttatca aaggcaaaag gattttgatt tttatagaaa
     4141 ggactggcaa tagcaggatt ttcagagtaa taaatcctat catcgccttc caaaatccag
     4201 acctctgtta ataggggata gtgattaaaa cggatagaat attctttact agtttgacct
     4261 gtatgaacca caaaattcaa gctttctata acatgtgaac ttgggtgttc aaagctaaat
     4321 aaagctccaa aataatcttc tttgtaggtt agcaaatcaa ttcgttgatc ctgacttttt
     4381 acaaaggagc aagtgtcata ttctccattc ttacgatggt aatgaatgcg catagggtag
     4441 ttatacattt tttatttttc ctttttactt tgtttctatt tcactaataa atttttgtca
     4501 atctcgtctc aattaacaga catagtcata ttctctaaac tctgttttta aacgatccat
     4561 tacaaacttt ctagccatgc ctcatctctg acctggatac caagttcttg tgctttttgc
     4621 agtttacttc cagcgtctgc acctaccacg acgaggtcgg tctttttaga aacactacct
     4681 gtcactttgg cacccagact ttcgagttta cttttagctt ctgagcgctt gagtcgttcc
     4741 aattttcctg tcaataccac ggtcaaacct gacaaggccg catccgctac taccgtctgt
     4801 cctttatagt ccagattgac cccagtttct ttcaattctc tgagcagaat ttcagagcct
     4861 tctgtcgcaa aataagtctg aagacttttg gcaatcacgc cacctagact ttcaatacta
     4921 gccacttcct ctgaatctgc ctgagacaga ttttcaattg aatggaaata ttgaagtaaa
     4981 agctgactag ccttgcttcc gacatgacga attcccaaac caaataagag cttctcggca
     5041 gaattttcct ttgatgcttg gatagcctga tacagtttag cagcggactt ttccttaacc
     5101 ccctctaaaa ggaggaaatc ctcttcttgc aaacgataaa tatccgccac atccttgact
     5161 aaattagcag caaaaagctt ctcaacaata gatggaccaa ggcctgtaat attcatagca
     5221 tcacgagaag caaagtgaat caagccttcc atgatttgag cagggcaacg cggattgata
     5281 caacgtaggg ccacttcatc ttcaaagtgc aacaagtcag agttacaact tggacagttt
     5341 gtagggatat ctagtttttc ttcagaaacc cgtttggact ctaccacacg taaaacggca
     5401 gggatgatgt caccagcctt atatacaatg accgtatcgt cttttcggat atctttttca
     5461 gcaatataat ctacattgtg cagggtcgca cggctaacag tcgtaccggc aagttgtact
     5521 ggtgttagat tagcagttgg agttacaaca ccggtacggc caactgtcca gtcaactgat
     5581 aagagttgag cttctttttc ttcagcaggg aacttgtagg ctactgccca ctttggagcc
     5641 ttaacggtaa aaccaagttc ttcttgactt gctaggtcgt tgaccttgat taccactcca
     5701 tcaatatcgt aaggcagatt ttcccgttcc tgtcctactt cttggataaa attccagatt
     5761 tcatctatgt tttcagccaa gattcgctta ggattgacca caaaacctag ttgttctagg
     5821 tacttcaaac ccttttcttg gctatcacga gttgaagggc tggcttcttg atagagaaac
     5881 gttgcaagat tacgcttggc aactactgct gtatccaact gacgcagagt tcctgctgcc
     5941 gcattacgag gattagcaaa ttcaggctct ccattttctt ggcgcacttg gttaacttgg
     6001 tcaaaggaag cgcgtggcat gtaacattcc ccacgaactg tgatatctag ttcttctggc
     6061 aaagtcaaag ggatgtcctt aacacgcttg aggttttctg tgatattttc accaattgaa
     6121 ccatctccac gtgttacccc agcaaccaaa atcccctttt cataagtcag cgagatagat
     6181 aagccatcga ttttcagctc acaaatatag gtcggatgag ccacttcctt acgaacacgc
     6241 gcatcaaaag catctagctc ctcacgtgaa aaagcatcct gcaaactata aagaggatac
     6301 tgatgactgt atttttcaaa accatctaaa accttgccac caacacgatg agtcggactg
     6361 tctgctagca cttgctctgg ataagcagtt tctaactcga ccaactcacg gtaaaggcgg
     6421 tcatactcac tgtctgaaac cgagggatta tcgctggtat agtactcagt cgcatagcga
     6481 ttgagcaaag cgactaactc attcattctt ttattcataa gaccatttta ccataaaaca
     6541 agccctcctc acaaacgaga agggcggaaa aaacacttag tttgaaatta tttttgaaac
     6601 tcaagcaacc ttatatcaat ttttcaaaat gagttcgaac ataaataaac gatatacaag
     6661 acaagatgat aacaccactt ccaattatca ggaaagaaga gagatgtaca cttggcaaga
     6721 ctgtcataaa tccttttgca ataggcataa atagaatagc taaggtaaaa attgtactca
     6781 gtactcttcc aagaaattcg ctctcaacct tggtttgtac ttgagtaaaa
//
LOCUS       DAVBCA010000085         6498 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.085, whole genome shotgun sequence.
ACCESSION   DAVBCA010000085 DAVBCA010000000
VERSION     DAVBCA010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6498)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6498)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6498
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.085"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..148)
                     /locus_tag="VQU19_001965"
     CDS             complement(<1..148)
                     /locus_tag="VQU19_001965"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2481159.1"
                     /translation="MITHRRFISCNEIIKHYKRLIDKAEKCVNDLMAEFNSVITTVTG
                     IGNRL"
     gene            307..2073
                     /gene="patB"
                     /locus_tag="VQU19_001966"
     CDS             307..2073
                     /gene="patB"
                     /locus_tag="VQU19_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HET2481160.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTHVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            2212..2901
                     /locus_tag="VQU19_001967"
     CDS             2212..2901
                     /locus_tag="VQU19_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HET2481161.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLDEL"
     gene            2905..3084
                     /locus_tag="VQU19_001968"
     CDS             2905..3084
                     /locus_tag="VQU19_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2481162.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            3071..4420
                     /locus_tag="VQU19_001969"
     CDS             3071..4420
                     /locus_tag="VQU19_001969"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HET2481163.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            4544..6004
                     /locus_tag="VQU19_001970"
     CDS             4544..6004
                     /locus_tag="VQU19_001970"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HET2481164.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDKFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            6018..6452
                     /locus_tag="VQU19_001971"
     CDS             6018..6452
                     /locus_tag="VQU19_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HET2481165.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAEDGQIFTGF
                     CMEGTCGVFHLCAERAALFNTYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNER"
BASE COUNT         2036 a         1251 c         1397 g         1814 t
ORIGIN      
        1 ctaaacgatt cccaatccca gtaaccgtcg tgatgaccga gttgaactca gccatcaagt
       61 cattgacaca tttttccgcc ttgtcaatga gcctcttgta atgtttgatg atttcattac
      121 acgagataaa acgtctatgc gttatcaaac tcattaccaa ttaaaacaaa aagctgtggt
      181 tagatccttt cggaaatcgt caagcgattg gaggaaatga actaatccac agcggcttat
      241 tccaagtata ccacttgggc tttggcagta gctaactgcg ctaaatataa tataaggagg
      301 agtaaaatga agacagttca atttttttgg cattatttta aggtctacaa gttctcattt
      361 gtagttgtca tcctgatgat tgttctggcg acttttgccc aagccctctt tccagtcttt
      421 tctggacaag cggtgacgca gctagccaat ttagttcaag cttatcaaaa tggcaatcca
      481 gaacttgtat ggcaaagcct atcaggaatc atggtcaatc ttggcctgct ggttttggtt
      541 ctatttatct ctagtgtaat atacatgtgt ctcatgacgc acgtgattgc agaatcgacc
      601 aacgagatgc gcaaaggcct ctttggtaag cttgctcagt tgacggtttc tttctttgac
      661 cgtcgacaag atggcgatat cttgtctcat tttaccagtg atttggataa tatcctccaa
      721 gcctttaacg aaagcttgat tcaggtcatg agcaatattg ttttatacat tggtctgatt
      781 cttgtcatgt tttcgagaaa tgtgacgctg gctctcatca ccattgccag caccccattg
      841 gctttcctta tgctgatttt catcgtgaaa atggcacgca aatacaccaa cctccagcag
      901 aaagaggtag ggaagctcaa cgcctatatg gatgagagca tctcaggcca aaaagccgtg
      961 attgtgcaag gaattcaaga ggatatgatg gcaggatttc ttgaacaaaa tgagcgcgtg
     1021 cgcaaggcaa cctttaaagg aagaatgttc tcaggaattc ttttccctgt catgaatggg
     1081 atgagcctga ttaatacagc catcgtcatc tttgctggtt cggctgtact tttgaatgat
     1141 aagtctattg aaacaagtac agccctaggt ttgattgtta tgtttgcaca attttcacag
     1201 cagtactacc agcctattat ccaagttgca gcgagttggg gaagccttca gttggccttt
     1261 actggagctg aacgaattca ggaaatgttt gatgcagagg aggaaatccg acctgaaaag
     1321 gctccaacct tcactaagtt gcaagaaagt gttgaaatca gtcatatcga tttttcatac
     1381 ttgcctgata aacctatttt gaaagatgtc agcatttctg cccctaaagg ccagatgaca
     1441 gcagttgttg ggccgacagg ttcaggaaaa acgactatta tgaacctcat caatcgcttt
     1501 tatgatgttg atgctggtgg tatttatttt gatggtaaag acattcgtgg ctatgactta
     1561 gatagtctta gaagcaaggt gggaattgta ttgcaagatt cggtcttgtt tagcggaacg
     1621 attcgagaca atatccgatt tggtgtgcca gatgctagtc aggaaatggt tgaggtagca
     1681 gcaaaagcaa cccacattca cgactatatc gaaagtttgc ctgataagta cgatactctt
     1741 attgatgatg accagagcat cttttcaaca gggcagaagc aattgatttc aatcgctcga
     1801 accctgatga cagatccaga agttctcatt ctcgatgaag caacttcaaa cgtagatacg
     1861 gtgacagaaa gcaagattca gcatgccatg gaggtggttg tagcaggtag aactagtttc
     1921 gtcattgccc accgcttgaa aaccattctc aatgcagatc agattattgt ccttaaagat
     1981 ggagaagtca ttgaacgtgg taaccaccat gaacttttga agctaggtgg cttttattca
     2041 gaactctatc acaatcaatt tgttttcgaa taagaaagaa gttgtcctat gtgggcagct
     2101 ttttcttgtc cataaaaaat gtttatcaca gccttaaaaa aaacatatta gacgaaagtc
     2161 attttgagtg atatgatagg actatcgtta gcattcgaaa ggagaggcat catggctaga
     2221 acggttgtag gagttgctgc aaatctatgt cccgtagacg cagaaggcaa aatcattcat
     2281 tcatctgtat cttgtagatt cgcagagatc attcgtcaag tcggtggtct ccctttagtc
     2341 attcctgttg gtgatgagtc agttgtacgt gattatgtgg aaatgattga caaactcatt
     2401 ttgacaggag gccaaaatgt tcatcctcag ttttatggag agaaaaagac cgtcgagagc
     2461 gatgattaca atctggtccg tgacgaattt gaattggcac tcttgaagga agcgcttcgt
     2521 cagaataaac caattatggc aatctgtcgc ggtgtccaac ttgtcaatgt tgcctttggt
     2581 ggaaccctca atcaagaaat cgaaggtcac tggcaaggac tacctttcgg gacatctcac
     2641 tctattgaga cagtagaagg aagcgtggtg gctaagctat ttgggaaaga aagtcaggtc
     2701 aactcagtcc atcgtcaaag cattaaagat ttggcaccta atttccgtgt aactgctatt
     2761 gattcaagag accaaactat tgaagcgatt gagtctatcg acgagcaccg cattatcggt
     2821 ttacagtggc atccagagtt tctggttaat gaagaagatg gcaatttaga attatttgag
     2881 tatttattgg atgaactgta acaattggaa catctggtcg ttctttcttt tattttttca
     2941 aaatttttag aatgtggtat tttacgcaaa cgtttgaatt ctgataaaaa ttggagaaat
     3001 tcgacaaaaa aacttgaaaa aaacgaaggt aagcgttatg atagaaaaga agaaatattg
     3061 gaggaagaac atgtcacata ttaaatttga ttattcaaaa gttttagaca aatttgttgc
     3121 accacatgaa gtggaataca tgcaatcaca agtaacagca gcagatgaat tgatccgtaa
     3181 aggaactggt gctggtagcg acttcttggg atggttggac cttcctgaaa aatacgaccg
     3241 cgaagaattt gaccgcatct tgaaagctgc tgagcaaatc aagtcagaca gcgatgtttt
     3301 ggttgtgatc ggtattggtg gatcttacct tggtgcaaaa gcagcaatcg acttcttgaa
     3361 tcaccatttt gctaacttgc aaacaaaaga agaacgcaaa gctccacaaa tcctttacgc
     3421 aggaaactca atctcatcta cttaccttgc tgacttggta gagtatgttg cagacaaaga
     3481 cttctcagta aacgtaattt ctaaatcagg tacaacaact gaaccagcga ttgctttccg
     3541 tgtctttaaa gaactcttgg ttaagaaata cggtcaagaa gaagctaaca aacgtatcta
     3601 tgcaacaact gaccgccaaa agggtgctgt taaggttgaa gcagacgcta acggttgggg
     3661 aacatttgtt gttccagatg atatcggtgg acgcttctca gtattgacag ccgttggttt
     3721 gcttccaatc gcagcatcag gagctgacat aaaagctctt atggaaggtg cgaatgcagc
     3781 tcgcaaagac tacacttcag acaaaatctc tgaaaacgaa gcttaccaat acgcagctgt
     3841 tcgtaacatc ctttatcgta aaggctatgc aactgagatc ttggtaaact atgagccatc
     3901 acttcaatac ttctcagaat ggtggaaaca attggctggt gaatcagaag gaaaagacca
     3961 aaaaggtatc tacccaactt cagccaactt ctcaactgac ttgcactcac ttggtcaatt
     4021 tatccaagaa ggaactcgta tcatgtttga aacagttgtc cgtgttgaca aacctcgtaa
     4081 aaacgtgctt attcctactt tggaagaaga ccttgacgga cttggttacc ttcaaggaaa
     4141 agacgttgac tttgtaaaca aaaaagcaac tgacggtgtt cttcttgccc acacagatgg
     4201 tgatgtacca aacatgtatg tgactcttcc agagcaagac gctttcactc ttggttacac
     4261 tatctacttc ttcgaattgg caattgccct ttcaggttac ttgaatgcta tcaacccatt
     4321 tgaccaacca ggtgttgaag cttataaacg taacatgttt gcccttcttg gaaaaccagg
     4381 atttgaagaa ttgagcaaag aacttaacgc acgtctataa tagaagaaaa gagtggtttg
     4441 cccactcttt ttactctctt tatccataga aattggactc agccaagact tgtgatataa
     4501 tatagaaagc aaaaaggcag acgcctagat aataggagaa actatgtcaa aagatatccg
     4561 cgtacgttac gcaccaagtc caacaggact actacacata ggaaatgctc gtacagcatt
     4621 gtttaattac ttgtatgcgc gccatcatgg tggaacattt ctcatccgta tcgaagatac
     4681 tgaccgtaaa cgccatgtcg aggatggtga acgttcacaa cttgaaaacc ttcgctggtt
     4741 aggcatggat tgggatgaaa gtccagaatc acatgagaat tatcgccagt ctgagcgttt
     4801 ggacttgtat caaaaataca tcgaccaact attagctgaa ggaaaagcct acaaatctta
     4861 cgttacagaa gaagagttgg cagctgaacg tgaacgtcaa gaagtagctg gcgaaacacc
     4921 acgctacatc aatgaatacc ttggtatgag tgaagaagaa aaagcagctt acatcgcaga
     4981 acgtgaagca gcagggatca tcccaactgt tcgtttggct gtcaatgagt caggtatcta
     5041 caagtggcat gatatggtca aaggcgatat cgaatttgaa ggtggcaata tcggtggtga
     5101 ctgggttatc caaaagaaag acggttaccc aacttacaac tttgccgttg ttatcgatga
     5161 ccacgatatg caaatctctc atgttatccg tggagatgac catattgcta atacaccaaa
     5221 acagcttatg gtctatgaag ctcttggttg ggaagctcca gagttcggtc acatgacctt
     5281 gattatcaac tctgagactg gtaagaagtt atctaaacgt gatactaata cacttcaatt
     5341 tatcgaagat taccgaaaga aaggttacct tccagaagca gtctttaatt ttattgctct
     5401 tcttggttgg aacccaggtg gtgaagatga gattttctct cgtgaagaac tcattaaact
     5461 ttttgatgaa aaccgcctca gcaagtcacc agcagccttt gatcagaaaa aactagactg
     5521 gatgagcaat gattatatca agaatgcaga ccttgaaacc atctttgaaa tggcaaaacc
     5581 attcttagag gaagcaggcc gtttgactga caaggctgaa aaattagttg agctctataa
     5641 accacaaatg aaatcagtag atgagattat cccattgaca gatcttttct tctcagattt
     5701 cccagaattg acagaagcag agcgcgaagt catgacgggt gaaacagttc caacagttct
     5761 tgaagcattc aaagcaaaac ttgaagcgat gacagatgat aaatttgtga cagaaaatat
     5821 cttcccacaa attaaagcag ttcaaaaaga aacaggtatt aaagggaaaa atcttttcat
     5881 gcctattcgt atcgcagttt caggcgaaat gcatgggcca gaattaccag atacaatttt
     5941 cttgcttgga cgtgaaaaat caattcagca tatcgaaaac atgctaaaag aaatctctaa
     6001 ataaagagga tacaataatg gacatctggg aaaagatgta cgaagaagca cagaaactat
     6061 acaatccaca tgaagtatca gactttgttt atgccaatca tgttgtagct gcagtagaag
     6121 cagaagatgg acaaatattt acaggattct gtatggaggg aacctgtggt gttttccatc
     6181 tctgcgcaga acgggcggcc ctcttcaata cgtaccaatt ttcaggacaa actaaggtta
     6241 agaaagtatt agcctttcga gacaaaccac cttatggtgg aagttcagcc atgccttgcg
     6301 gtgcttgtag agaattcctt ttagagctta atgctgaaaa taaagatgca gaattcatga
     6361 tggactataa tataagaaaa acagttaaag tcgcagaact aatcccttat tggtggggag
     6421 aagaacgtgc ttctaagttt aatgagcgat agaagagtca gtataattct ggcttttttt
     6481 actataagtt gaaaaaat
//
LOCUS       DAVBCA010000086         6476 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.086, whole genome shotgun sequence.
ACCESSION   DAVBCA010000086 DAVBCA010000000
VERSION     DAVBCA010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6476
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.086"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            53..1015
                     /locus_tag="VQU19_001972"
     CDS             53..1015
                     /locus_tag="VQU19_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HET2481166.1"
                     /translation="MNMSNITIDGQEMDLSQTMPSYAQVVSLYDDTSISVSSNETDKV
                     LAGSLYTDTNEQGLTIPSSLLKNWNEQTGKNLTANDLIGKSVSASIVESAAETSKIAQ
                     FQTKIVRVINDEDDMEDSNSFMLSHQMETILKEAGFTKAVSYFILELKDPSQTKVVTE
                     ELQKNKKYTVLSQQRVLDIVIIFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRS
                     KEIGVMKAVGYQNRDVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSIT
                     KVFELNLLSVLGTLVFALLLGYVSAYFPARKISKMDPVEPLRYE"
     gene            1192..2199
                     /gene="gap"
                     /locus_tag="VQU19_001973"
     CDS             1192..2199
                     /gene="gap"
                     /locus_tag="VQU19_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HET2481167.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFIKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(2266..3102)
                     /locus_tag="VQU19_001974"
     CDS             complement(2266..3102)
                     /locus_tag="VQU19_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET2481168.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVHWNEIVNPGD
                     VCQLTFDEEDYPQKTIPWGNPDLVQEVYQDQYLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGQYAETYVSRLKQFSNKTSLARCKLKTGRTHQIR
                     VHLSHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLEKLTFTTLSNTFEKELKK
                     NG"
     gene            3228..5423
                     /locus_tag="VQU19_001975"
     CDS             3228..5423
                     /locus_tag="VQU19_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HET2481169.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMASQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVAAVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIASHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYIMAGKTGTTEAVFNPEYTSDQWVIAYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            5476..5628
                     /gene="rpmG"
                     /locus_tag="VQU19_001976"
     CDS             5476..5628
                     /gene="rpmG"
                     /locus_tag="VQU19_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET2481170.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            5638..5814
                     /gene="secE"
                     /locus_tag="VQU19_001977"
     CDS             5638..5814
                     /gene="secE"
                     /locus_tag="VQU19_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HET2481171.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            5870..6406
                     /gene="nusG"
                     /locus_tag="VQU19_001978"
     CDS             5870..6406
                     /gene="nusG"
                     /locus_tag="VQU19_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HET2481172.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAEL"
BASE COUNT         2012 a         1128 c         1418 g         1918 t
ORIGIN      
        1 cacggataca gttgggaaag aagctattaa acatttggag agtccttttg ggatgaacat
       61 gtcaaatatt actatagatg ggcaagaaat ggatctgagt caaacgatgc cttcttatgc
      121 tcaagtagtg agtctttatg atgatacaag tatctctgtt agtagtaatg agacggacaa
      181 agtgttggct ggctccctct atactgatac aaatgaacag ggattaacga ttccaagcag
      241 tttactaaaa aattggaatg aacagacagg aaaaaatttg acagctaatg atcttattgg
      301 caaatcagtc tcagccagca ttgtagaaag tgctgccgaa actagtaaga ttgctcaatt
      361 tcaaacgaag attgtacgtg taatcaatga tgaagatgac atggaggaca gcaacagttt
      421 catgctgtct catcaaatgg aaacgatttt gaaagaggct ggatttacga aagctgtatc
      481 ttattttatc ttggaactca aagatccatc acagacaaaa gtagtaacag aagaattaca
      541 gaaaaataag aagtatactg tgctttctca acagagagtt cttgatattg tgattatctt
      601 tattcgtgtt attcagggat tattgattgt gctttcatca caagctattg tggtagcagc
      661 ggttatgatt ggtatcatta tttacatcaa tatcatgcag cgttccaagg aaataggtgt
      721 catgaaggca gttggttatc agaatcgtga tgtcaaagga atttttattt acgaggctat
      781 ctggattgta ggcatcgcct tgctgctggc atttttggtt gcacaagggg tgggaagttt
      841 ggcgaatgcg attgtaagtc acttttaccc atccatcact aaagtttttg aattaaatct
      901 tttatctgtt ttaggaactc tagttttcgc tctattactt ggttatgtct cagcctactt
      961 cccggcgcgt aagattagta aaatggatcc tgtagaaccg ttacgctatg aatagtaagg
     1021 gattccttga tttacagtct taaaaagaaa ctaacataga aaaacaatgg acatacttgc
     1081 aattcaactc aaatagttgt ataataggtt tgttgaaagg tgatttgtag tgattcaagt
     1141 tactcttttc acaataaaaa tttcatgatt ttcataagga ggaaatcact aatggtagtt
     1201 aaagttggta ttaacggttt cggacgtatc ggtcgtcttg ctttccgtcg tatccaaaac
     1261 gtagaaggtg ttgaagttac acgcatcaac gaccttacag atccagttat gcttgcacac
     1321 ttgttgaaat acgacacaac tcaaggtcgt ttcgacggta ctgttgaagt taaagaaggt
     1381 ggatttgaag ttaacggtaa attcatcaaa gtttctgctg aacgtgatcc agaacaaatc
     1441 gactgggcta ctgacggtgt agaaatcgtt cttgaagcta ctggtttctt tgctaagaaa
     1501 gaagcagctg aaaaacacct taaaggtgga gctaaaaaag ttgttatcac tgctcctggt
     1561 ggaaacgacg ttaaaacagt tgtattcaat actaaccacg acgttcttga cggtactgaa
     1621 acagttatct caggtgcttc atgtactaca aactgcttgg ctccaatggc taaagctctt
     1681 caagacaact ttggtgttgt tgaaggattg atgactacta tccacgctta cactggtgac
     1741 caaatgatcc ttgacggacc acaccgtggt ggtgaccttc gccgtgctcg cgctggtgct
     1801 gcaaacatcg ttcctaactc aactggtgct gcaaaagcta tcggtcttgt aatcccagaa
     1861 ttgaatggta aacttgatgg atctgcacaa cgcgttccaa ctccaactgg atcagttact
     1921 gaattggtag cagttcttga aaagaacgtt actgttgatg aagtgaacgc agctatgaaa
     1981 gcagcttcaa acgaatcata cggttacaca gaagatccaa tcgtatcttc agatatcgta
     2041 ggtatgtctt acggttcatt gtttgacgca actcaaacta aagttcttga cgttgacggt
     2101 aaacaattgg ttaaagttgt atcatggtac gacaacgaaa tgtcatacac tgcacaactt
     2161 gttcgtactc ttgaatactt cgcaaaaatt gctaaataat tcttgagttg atagaaagca
     2221 aggctttgtg gtcttgcttt ttatatggaa aaatggatga cacgatcatc cattcttttt
     2281 taattctttt tcaaatgtat ttgaaagggt agtgaaagtt agcttctcta aagtaagtgg
     2341 gtgggtaaag gaaagtcgga aggcatgaag cataagccga cttgtctttg atttactatt
     2401 atagagaggg tcgcccagga taggaagatt atgatgcgaa aggtgcacac gaatctgatg
     2461 ggttcgccct gtctttagct tgcaacgagc caaggaagtc ttgtttgaga attgctttaa
     2521 tctgcttaca tacgtttcag catattgccc attttttgca tcaactattc tttttctacg
     2581 atcatggcga tcacgtccaa ttttgtctct gaaaacaagt tcttttctgt tgatatttcc
     2641 atcaactaga gcccaatatt ctctagaaat ctcttttttc tccaataagc gattgagaat
     2701 gggcaggata aaaggatttt tggcaaagag aactaagcca ctggtttcca tgtccagacg
     2761 atgaacgaca tagcaggttt ggccaacata ggtactgaca tggttaagaa gggcaatttc
     2821 gtttggttga ttaccatgcg ttttcatccc ctctggtttg tttacaataa tcaagtattg
     2881 atcttgataa acttcctgca ctaagtctgg gttgccccaa gggatcgtct tttggggata
     2941 atcttcctcg tcaaaagtca actggcaaac atctccagga tttacgattt cgttccagtg
     3001 gacttcttct tgatttatca aaatatgttt cttgattctc aaaaaatgac ggatttttct
     3061 agggatgagg agttgttcct caagtaattg ctttaccgtc atttgaggta gagaggcggg
     3121 taatgtaaat gtgaattgca tacagatatt gtaacaaaaa aagccctatt tggataggaa
     3181 atagctaaat tcttgtcttc ctatgatgaa gatgataaaa taaacgcatg aaattagata
     3241 aattatttga gaaatttctt tctcttttta aaaaagaaac aagtgaacta gaggactctg
     3301 attctactat cttacgtcgc tctcgtagtg atcgaaaaaa attagcccaa gtaggtccga
     3361 ttcgaaaatt ctggcgtcgt tatcatctaa caaagattat ccttatacta ggtttgagtg
     3421 caggcttgct agttggaatc tatttgtttg ctgtagccaa gtcgaccaat gtcaatgatt
     3481 tgcaaaatgc cttgaaaact cggactctta tttttgaccg tgaagaaaaa gaggctggtg
     3541 ccttgtctgg tcaaaaggga acctatgttg agctgactga tatcagtaaa aacttgcaga
     3601 atgctgttat tgcgacagaa gaccgttctt tctataaaaa tgacgggatt aactatggcc
     3661 gtttcttctt ggctattgtc actgctggac gttcaggtgg tggctctacc attacccaac
     3721 agctggctaa aaacgcctat ttatcacagg atcaaactgt tgagagaaaa gcgaaagaat
     3781 ttttccttgc cttagaatta agcaaaaaat atagtaagga gcaaattcta accatgtacc
     3841 ttaacaacgc ttattttgga aatggtgtgt ggggtgtaga agatgcgagt aagaaatact
     3901 ttggagtttc tgcatcagaa gtgagtctgg atcaagctgc gactctggca gggatgctca
     3961 aggggccgga actgtataat cccttgaatt ccgtagaaga ttctactaat cggcgcgata
     4021 ctgtcttgca gaatatggtt gcagcaggat atattgataa aaaccaagaa accgaagctg
     4081 ctgaagttga tatggcttcg caattgcacg ataagtatga aggaaaaatc tcagattacc
     4141 gttacccctc ttattttgat gcggtggtta atgaagctgt ttccaagtat aatctaacag
     4201 aggaagagat tgtcaataat ggctaccgca tttacacaga gctggaccaa aactaccaag
     4261 caaatatgca gattgtttat gaaaacacat cgctatttcc gagggcagag gatggaacgt
     4321 ttgctcaatc aggaagtgta gctctcgaac cgaaaacagg gggagttcgt ggagttgtcg
     4381 gtcaagttgc tgacaatgat aaaactggat tccggaattt caactatgca acccaatcaa
     4441 agcgtagtcc tggttctaca attaagcctt tagttgttta tacgccagca gttgaagcag
     4501 gctgggcttt gaataagcag ttggataacc ataccatgca gtatgacagc tataaggttg
     4561 ataactatgc agggatcaaa acgagtcgag aagttcctat gtatcaagcc ttggcagaat
     4621 cgcttaatct acctgctgtt gccgctgtta atgatttggg tgtcgacaag gcttttgagg
     4681 caggcgaaaa attcggactc aacatggaaa aggtcgaccg tgttcttggt gtcgccttgg
     4741 gaagcggtgt tgaaaccaac cctcttcaaa tggctcaagc atacgctgcc tttgcaaatg
     4801 aaggtttaat gcctgaagct cattttatta gtagaattga aaatgctagt ggacaagtta
     4861 ttgcgagtca taaaaattca caaaaacggg tgattgataa gtctgtagct gacaagatga
     4921 ccagtatgat gttggggact ttcaccaacg gtaccggtat tagttcatcg cctgcagact
     4981 atattatggc agggaaaact ggaacaactg aagcagtttt caatccggag tacacaagtg
     5041 accagtgggt aattgcttat actccggatg tagtgattag ccactggctt ggctttccta
     5101 ccactgatga aaatcactat ctagctggct ctacttcaaa cggtgcagct catgtcttta
     5161 gaaacattgc caataccatt ttaccttata cgccaggaag tacctttacg gttgaaaatg
     5221 cttataagca aaatggaatt gcaccagcca atacaaaaag acaagtacaa accaatgata
     5281 atagccagac agatgataat ttgtctgata ttcgagggcg tgcgcaaagt ctagtagatg
     5341 aggctagccg ggctatctca gatgcgaaga ttaaggaaaa ggctcaaaca atatgggatt
     5401 cgatagtcaa tctatttcgc taagatgctt gtcaaagcct agctttcttg ttataatgga
     5461 taggatggag gcgttatggc actaaaaaaa gcaagcctag cttgtgcggt ttgtggttcg
     5521 agaaactatt caatcaagat cagcggaaac cccaagccta cacgactaga agtaaataaa
     5581 ttttgtaagc attgtggcaa gtacactaca cacagagaaa cgagatagga gagagcgatg
     5641 cgttttattg gagatatttt tagacttctt aaagacacaa cgtggccaac tcgcaaggaa
     5701 agctggagag attttcgttc tatcatggaa tacacagctt tctttgtagt aattatttac
     5761 atttttgacc agttgattgt ttcaggtttg attcgattta ttaacatttt ttagaagatt
     5821 agtggagtta attacactag aaatcttcta tattatgaaa ggaaatatca tggatagttt
     5881 tgataaaggg tggtttgttt tacaaactta ttctggttat gaaaataagg tgaaagaaaa
     5941 tctattacaa cgtgcacaaa cctacaatat gttggataat attctacgcg ttgaaattcc
     6001 aacacaaaca gtgcaagttg aaaaaaatgg aaagagaaaa gaagtagaag aaaatcgctt
     6061 tccaggttat gttcttgtag aaatggtcat gacagatgaa gcttggtttg ttgttcgaaa
     6121 cacaccaaat gttacaggat ttgtcggatc acacgggaac agatcaaaac caactccatt
     6181 attggaacaa gaaattcgtg acattttggt atctatggga caaactgttc aagaatttga
     6241 tttcgatgtt gagattggtc aaactgtacg tattattgat ggtgcttttg cagactacac
     6301 tggtaagatt acagaaattg ataataacaa agtgaaaatg attatctcta tgtttggtaa
     6361 tgacacagtt gcagaagtaa acctaaacca aatcgcagaa ttataaccct gagagaggct
     6421 ggagcctctc ttttttgtgc agtttaggag ctaaagggaa cagaatggag aaaatg
//
LOCUS       DAVBCA010000087         4999 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.087, whole genome shotgun sequence.
ACCESSION   DAVBCA010000087 DAVBCA010000000
VERSION     DAVBCA010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4999)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4999)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4999
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.087"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(84..161)
                     /locus_tag="VQU19_001979"
                     /pseudo
     CDS             complement(84..161)
                     /locus_tag="VQU19_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            319..537
                     /locus_tag="VQU19_001980"
     CDS             319..537
                     /locus_tag="VQU19_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001859328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HET2481173.1"
                     /translation="MKKISVTVIGYFEINIDENITDILYVNGTAILYHYLRSIVSIVS
                     AIDSSEAMLLPTINVLELLDKSQPFEEE"
     gene            1582..2574
                     /locus_tag="VQU19_001981"
     CDS             1582..2574
                     /locus_tag="VQU19_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2481174.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPDSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYDGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            2576..3394
                     /locus_tag="VQU19_001982"
     CDS             2576..3394
                     /locus_tag="VQU19_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HET2481175.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVIYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            3396..4181
                     /locus_tag="VQU19_001983"
     CDS             3396..4181
                     /locus_tag="VQU19_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2481176.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            4220..4498
                     /locus_tag="VQU19_001984"
     CDS             4220..4498
                     /locus_tag="VQU19_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HET2481177.1"
                     /translation="MFVIEEVKDENQKKAVVAEVLKDLPEWFGIPESTQAYIEGTTTL
                     QVWTAYQESDLTRFVSLSYSSEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            4483..4680
                     /locus_tag="VQU19_001985"
     CDS             4483..4680
                     /locus_tag="VQU19_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2481178.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEGSNKDYDRTNDFYRGLGFKKL
                     EIFPQLWNPQNPCQILIKKLE"
BASE COUNT         1431 a          833 c         1043 g         1692 t
ORIGIN      
        1 gtccatcgag ctttctaata ctcttcgaaa atctcttcaa accacgtcaa cgtcgccttg
       61 ccgtgcgtat ggttactgac ttcgtcagtt ctatccacaa cctcaaaaca gtgttttgag
      121 caacctgagg ctagtttcct agtttgctct ttggttttca tttagtataa cagattgtta
      181 gaagttggtt taaatttcct aatcagtttg ttcacattta ccttcgatat attatatccc
      241 atagttaagg ttggtcatac agatgattat agtcatggag ccgtaaaact tagtgtttct
      301 ttagttgaca aagatgccat gaaaaaaata tctgtaactg taataggata ttttgaaata
      361 aatatagatg aaaatatcac cgatattcta tacgtaaatg gtactgctat tctttatcat
      421 tatttacgtt ctattgtttc aatagtttcg gcaattgata gcagtgaagc aatgttgcta
      481 cctaccatta atgttttaga gttactagat aaatctcaac cttttgaaga agaataattt
      541 attagctcac taaattgagg gtaaggaaaa gtaaaatcag taagaaaaat gtcttgcatt
      601 atacagcaac cttttgggaa tgagtagatg gattgaataa aattttatta agagtggatg
      661 atttatctgt agattattat tggacagtta gtcttgaagt agtctaagaa ttaggttata
      721 atcagtagaa tccttgctaa taatgaggag gttagtttat gtatagtaga ctgaatctaa
      781 aatagtacga aacaattgct aaaacattta tagaaattaa ttttactttc ccaatcgatt
      841 tgttctcatc ttatttcaat ccgctatata ttatggtatc gaatcttcat cagaatgata
      901 aaattaatca attgatatct gattacaaac agaatatgaa agctttttat atcactattg
      961 aaaaatttat acgagatgat gaaagcctta agtgttattt tataaaggtt atttcaagtc
     1021 gttccaaggt aacaagtcta gatcagattg aagctgataa aacgatacaa agaaaatatt
     1081 caagtgagct aaaaaaattt attggatttt ataatgagat tatttgtgag gaaaatagtt
     1141 tcctacatgt acgaaagagg tggtcgagtt ggtttaggta gtcgatgcgt gagttgataa
     1201 ttctcagggt atggacttct ttttcatgaa tgaggtaaaa gagcaggtat tgtttagaga
     1261 caatcattct gagcatattt tctggataga gggagtatcc gattttatga tcaaagttaa
     1321 taccgccctc tggtgagaag atgagtaggt tggtaattta aactattaaa cagaattttt
     1381 gattaaaagt attattttat gagagaaatc ctaatttcac aatccatagg caaactcttg
     1441 catttcgttt tttattggac tataataggt tggtataaag ccttttgtag taataaaatg
     1501 tagaaggtgt agaaagcaag gatttagaat atttgtagtt aaaaacacaa tgttgctatt
     1561 ccttacgata gggagataga tatggcaatg atagaagtgg aacatcttca gaaaaatttt
     1621 gtgaagactg ttaaggaacc gggcttgaag ggggctttgc gctcctttat tcatcctgaa
     1681 aagcagacct ttgaagcggt caaggatttg acctttgagg ttccaaaagg gcagatttta
     1741 ggatttatcg gggcaaatgg tgctgggaag tcgacaacca ttaaaatgct gacaggaatt
     1801 ttgaaaccaa catctggttt ttgtcggatt aacggcaaga ttccccagga caatcggcaa
     1861 gattatgtca aagatattgg cgtagtcttt ggacaacgca cccagctatg gtgggatttg
     1921 gctctgcaag agacctacac tgtcttaaaa gagatttatg atgtgccaga ctcgctcttt
     1981 cataagcgta tggacttttt gaatgaagtc ttggatttga aggactttat caaggatccc
     2041 gtgcggactc tttcactggg acaacggatg cgggcggata ttgcggcctc cttgctccac
     2101 aatcccaagg ttcttttttt agatgagccg accattggtt tggacgtttc ggttaaggat
     2161 aatattcgtc gggcaattac tcagatcaat caagaggaag aaactaccat tcttttgacc
     2221 actcacgatt tgagtgatat tgagcaactt tgtgatcgga ttttcatgat tgacaagggg
     2281 caagagattt ttgatggaac ggtgagccaa ctcaaggaga cctttggtaa gatgaagact
     2341 ctctcttttg aactgctacc aggtcaaagt catctcgtct ctcactatga cggtctgtct
     2401 gatatgacca ttgatagaca aggaaacagc ctcaacattg aatttgatag ttctcgctac
     2461 cagtcagctg acattatcaa gcaaaccctg tctgattttg aaatccgcga tttgaagatg
     2521 gtggatacgg atattgagga tattatccgt cgcttctacc gaaaggagct ctaggatgat
     2581 caaattgtgg agacgttata aaccctttat caatgcaggg gttcaggagt tgattactta
     2641 ccgagtcaac tttattctct atcggattgg cgatgtcatg ggggcttttg tggcctttta
     2701 tctctggaag gctgtctttg attcttcgca agagtctttg attcagggct tcagtatggc
     2761 ggatatcacc ctctacatca tcatgagttt tgtgaccaat cttctgacta gatccgattc
     2821 gtcctttatg attggggagg aggtcaagga tggctccatt atcatgcgtt tgttgcgacc
     2881 agtgcatttt gcggcctcct atcttttcac cgagcttggt tccaagtggt tgatttttat
     2941 cagcgttggc cttccatttt taagtgtcat tgtcttgatg aaaatcatat cgggtcaagg
     3001 tattgtagag gtgctaggat taactgtcat ttatcttttt agcttaacgc tcgcctatct
     3061 gattaacttt ttctttaata tttgctttgg attttcagcc tttgtgttta aaaatctttg
     3121 gggttccaac ctacttaaga cttccatagt ggcttttatg tcggggagtt tgattccctt
     3181 ggcattcttt ccaaaggttg tttcagatat tctctccttt ttgccttttt catccttgat
     3241 ttatactcca gttatgatca ttgttggaaa atacgatgcc agtcagattc ttcaggcact
     3301 ccttttgcag ttcttctggc tcttagtgat ggtgggattg tctcagttga tttggaaacg
     3361 ggtccagtcc tttatcacca ttcaaggagg ttagtatgaa aaaatatcaa cgaatgcatc
     3421 tgatttttat cagacaatac atcaaacaaa tcatggaata taaggtggat tttgtggttg
     3481 gtgtcttggg agtctttctg gctcaaggct tgaatctctt gtttctcaat gtcatctttc
     3541 aacatattcc attcctagaa ggctggacct ttcaagagat agctttcatt tatggatttt
     3601 ccttgattcc caagggaatg gaccatctct tttttgacaa tctctgggca ctagggcaac
     3661 gcctagtccg aaaaggggag tttgacaagt atctgactcg tcccatcaat cctctctttc
     3721 acatcctagt tgaaaccttt cagattgatg ccttgggtga actcttagtc ggtggtattt
     3781 tattgggaac aacagtgacc agcattgttt ggactcttcc gaaattcctg cttttcctag
     3841 tttgtattcc ttttgcgacc ttgatttata cttctcttaa aatcgcaaca gccagtatcg
     3901 ccttttggac taagcagtca ggcgccatga tttacatctt ctatatgttc aatgactttg
     3961 ctaagtatcc gatttctatt tacaattctc ttcttcgttg gttgattagc tttatcgtgc
     4021 ctttcgcctt tacagcctac tatccagcta gctatttctt acaggaaaag gatgtgttct
     4081 ttaacgtagg aggtttgatg ttgatttctc tggttttctt tgttatttcc cttaaacttt
     4141 gggataaggg cttagattcc tacgaaagtg cgggttcgta aaagctaaag taagactaaa
     4201 atcaagaaag aaacttatga tgtttgtaat tgaagaagtc aaggatgaaa atcaaaaaaa
     4261 ggcagttgta gctgaggttt tgaaggattt gccagaatgg tttggaatcc cagaaagcac
     4321 acaagcctat atagaaggaa ccacgacact gcaagtttgg accgcctatc aggagagtga
     4381 tttgactaga tttgtaagct tatcctattc gagtgaagat tgtgcagaga ttgattgtct
     4441 cggcgtaaaa aagcttatca aggtagaaaa attgggagcc aattgcttgc tactttagag
     4501 agtgaagctc gtaaaaaagt tggttatctg caggtcaaaa cagtggcaga aggttctaat
     4561 aaagattatg atcgaacaaa tgacttttat cgaggtcttg gctttaaaaa gttagagatt
     4621 tttcctcaac tatggaatcc gcaaaatcct tgtcagattt tgattaaaaa gcttgaataa
     4681 tattacttga catctattct cagagtgcca tactgtaagt gtaatcgccg atttagctca
     4741 gttggtagag caaggcactc gtaaagccta ggttataggt agataaacga ctgaggagtt
     4801 gaaaaaatag ataggtagaa gataaccgtt aagccttatt cttagcggtt atttatattg
     4861 tttaatagcg ctgatatttc atcaattatg cctgttttcg tgtttctggt agttgttcaa
     4921 gtttattgct actatttttg atggtatgaa tgtgcttata atgtatcccg gttaacgaaa
     4981 gttttggact tatactctt
//
LOCUS       DAVBCA010000088         4613 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.088, whole genome shotgun sequence.
ACCESSION   DAVBCA010000088 DAVBCA010000000
VERSION     DAVBCA010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4613)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4613)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4613
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.088"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(374..1570)
                     /gene="tuf"
                     /locus_tag="VQU19_001986"
     CDS             complement(374..1570)
                     /gene="tuf"
                     /locus_tag="VQU19_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HET2481179.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(2481..3350)
                     /locus_tag="VQU19_001987"
     CDS             complement(2481..3350)
                     /locus_tag="VQU19_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HET2481180.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTEKPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(3573..4253)
                     /locus_tag="VQU19_001988"
     CDS             complement(3573..4253)
                     /locus_tag="VQU19_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET2481181.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVISGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPEKPEIPSPQEPGTPGEPTPEKPIPQPNPEHPSVPTPNPELPNQETPTPDK
                     PTPEPGTPKAETPVNPDPEVPTYETGKREELPNTGTEANATLASAGIMTLLAGLGLGF
                     FKKKEDEK"
     gene            complement(4211..>4613)
                     /locus_tag="VQU19_001989"
     CDS             complement(4211..>4613)
                     /locus_tag="VQU19_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HET2481182.1"
                     /translation="FKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANYYKE
                     GSQEKLAESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPANAY
                     QKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
BASE COUNT         1293 a          931 c          903 g         1486 t
ORIGIN      
        1 tataatgctt tttgatttta gtctagtatt atactcttcg aaaatctctt caaaccgcgt
       61 cagcttcgcc ttgtcgtata gatgttactg acttcgtcag ttctatctac aacctaaaaa
      121 cagtgttttg agcagtctgt agctaacttt ctatagtaaa atgaaataag aacaagacaa
      181 atcgatcagg acagtcaaat cgatttctaa caatgtttta gaagtaaatg tgtactattc
      241 tagtttcaat atattatagt ttgctctttg attttcattg agtattagtt caatatctaa
      301 aaaaagaacc ttgccaagca agattctttt agtgtctgac ttaaataatt gttcttctgg
      361 gaactaaatc gaattaagct tcgatttctg taaccatacc tgaaccaaca gtacgtccac
      421 cctcacggat agagaatgta gtaccttgtt ctacggcgat tgggtgaatc aactcaacgt
      481 cgattgtcac gttatcacca ggcattacca tttcagtacc tgctggaagt tcgattgaac
      541 ctgtaacgtc agtagtacgg aagtagaatt gtggacggta gttgttgaag aatggagtgt
      601 gacgtccacc ttcttcttta gtaaggatgt agacttcacc tttgaattta gtgtgtgggt
      661 tgattgaacc tggtttagcg ataacttgtc cacgttcgat ttcatcacgt tgaacaccac
      721 gaagaaggac acctacgtta tctccagcaa gaccttcgtc aagttgttta cggaacattt
      781 caacaccagt aacaactgct ttttgagttt cttctttgat accaacgatt tcgatttcgt
      841 cgttgacttt aacgatacca cggtcgatac gtcctgaagc aactgtacca cgtccagtga
      901 ttgagaatac gtcctcgact ggaagaagca atggtttgtc agtgtcacgt tctggttctg
      961 ggatatactc atcaactgtg ttcatcaatt ccataacgat gtcttcgtat ttagagtcac
     1021 cttcaagagc tttaagtgct gaaccttgga taactggaag atcgtcacct gggaagtcgt
     1081 attctgacaa taggtcacgg atttccattt caaccaattc aagcaattct tcgtcgtcaa
     1141 ccaagtcaac tttgttcatg aagacgataa ggtgtttaac accaacctga cgtgaaagaa
     1201 ggatgtgctc acgagtttgt ggcattggtc cgtcagttga agctactaca aggatagctc
     1261 cgtccatttg agcagcacca gtgatcatgt ttttaacgta gtccgcgtgt cctggagcgt
     1321 cgatgtgagc gtagtgacgt ttttcagttt cgtactcaac gtgcgcagtg ttgatagtga
     1381 taccgcgttc gcgttcttct ggagcagcat cgatagacgc atagtcttta ggttggttaa
     1441 ctgatgaagg caagcgacgt gccaaaacag ttgtgatagc tgcagttagg gtagttttac
     1501 cgtggtcaac gtgtccgata gtaccaatgt taacgtgtgg tttactacga tcgtattttt
     1561 cttttgccat ttgagtaaaa gcctccaata aaatatattt tatagataga cagtaggcaa
     1621 tacagtctaa ctttccttac tattttatca aatttcagct aaattgcaag tgttttacaa
     1681 cgtttttgtg aattattctt ggtaaaaatt taactaatta atagaaagta ctaaatagac
     1741 ttatccttca aggagttttc agcattatcc atccactcac ttgctgaaaa tgtaaacagt
     1801 ctctggttta tatagtaaaa tgaaacaaga atagagcaaa tcgatcagga cagtcaaatc
     1861 gatttctaac aatgttttag aagtagatgt gtactattct agtttcaatc tactatacaa
     1921 cctcaaaact gtgttttgaa caacctgcgg ctagcttctt agtttgccct ttgattttca
     1981 ttgagtataa aattgcagat aaaacgataa caatcatagg actcagcaga gtcaatgtag
     2041 gtcgaagaat agccccccta atcgcttatt ttatagcaaa atgaaataga aactgaacat
     2101 tttgttgagg aaggtaaatc aattcctcac aatgtttgag aaagaaggga ggactattcc
     2161 aacttcaacc cactataaag cagacttaca agatagggaa cccatctccg ataatatata
     2221 gtagaatgaa aactgcacaa tttgattgga gaattcaaac caatttctaa caatgtttta
     2281 gaaacaaggg tctattattt caactgcaac ctactatagc ccattgaagc tggaatagcc
     2341 cactgagact tctaaaccac tgctggagag gagtttgttt agagtttctt tcatttccct
     2401 aaaaaatcaa aaagagagaa ccagtctgat cctctcttac ttatagatgg tgctcactca
     2461 aatgttaaag gagctatttc ttagagataa aggaatttga atacagctac tgccgcaatt
     2521 gctgctgcga taggtgctac tactggtacc caagaatacc accattttga atcgccttta
     2581 tgctcaccaa gaactgattt tggaaggaaa gcatgaagga gacgtggtcc caagtcacgg
     2641 gctgggttca aggcaggtcc tgtaggtcct ccaagtgatg ttaccaaagc cataacgagg
     2701 aatccaagtg ccaagtgagc cacagaaagt cctgaagcag tgtgtggagc cacctgtgct
     2761 ttaatagcca agtcagaaaa atcaactgtt tgtcctgctt ctattgcctt ttgtttcatg
     2821 aattgaagca cttcagcacc aaagaagttt ttagtcaaac caagagctgc aaagaacaaa
     2881 acaaatgaac caacaaactc attaatcaaa ccattgacag ttgctgcata gcgactttct
     2941 tttgtaccat ggtcaatact tgaaatagtt gagaaagttc ccaagatgtt atttggtttt
     3001 tcagttttca agtagaatgg acggtatgtt gccacaacta aggcttggcc aaagatagcc
     3061 cccaagactt gcgcgataat gtaaggtacc acttgtgccc aagggaaaag accgctaact
     3121 gcaagcccta gagtgaaagc agggttgatg tgattcccag atacgttacc aaacatcaag
     3181 gctgggatca taacccccat accataacca acagcgatga cgatccagcc actttggtga
     3241 cctttcgtac ctttaagttc aacgttggca actgcaccat tcccaagaat gatcaaaatg
     3301 gcagttccca aaaattcagt ggcatacttc agtgcccatg tgaaatccat ttgctagatt
     3361 ctccttaaaa ttttttagat attccttatt ttatcaattt ttaccctatt tagcaactga
     3421 tttctggaaa tatttttaaa aaaataggat tcatagtttc ccagttcaac gtacttgtaa
     3481 gcgtttttat tcttcacgaa agacctcatt ctcaaaacca ggaaaaagcc cacatctgtg
     3541 atcttttcct ggttcctaga ttctaaaatc tattattttt catcttcttt tttcttgaag
     3601 aatcctaatc ctagaccagc taacaaggtc atgataccag cactagccaa ggtagcatta
     3661 gcttctgtac ctgtgtttgg caattcctct ctcttacctg tctcataagt cggaacttct
     3721 gggtctggat tcactggagt ttcagctttt ggagtacctg gttctggagt tggtttatct
     3781 ggtgttggag tctcttgatt tggtagttct gggtttggtg tcggaacact tggatgctct
     3841 ggatttggtt gtgggattgg tttttctgga gtcggttcac ctggagtacc tggttcctga
     3901 ggacttggaa tttctggttt ttctggagtt ggtttatctg gtgttgataa acggtcatac
     3961 cttaccgtta tttctttatc actagagtct gacgtaactt cttgtgattc aactgttgga
     4021 atatctggat ctttgtactt gtcaatctta ccagatataa cctcgtccca gtttcctgtt
     4081 gtccattcac cgtaggttac aactcccgtg accttgttct cagtttttgt acggcttaag
     4141 gttacaggtt gaacaacatc ttcttttaca ttttggttcg taactttatc aacgtaatga
     4201 atgatacgcg ttatagtctt cgtctcagta gaggttgctg ttttgggaac cactgtttcc
     4261 tcaacattct cacggtagta atagtcaact gttgcaccgt cttctggtac gcatttgcag
     4321 gagttgctac caaggtgtat gttgttttcc ttgtgataac tcggtcttct ttgtcctcag
     4381 ttgttgtttt cccttcaata gtttttgatt ctgtggtata ctcagaacct atcgctaaat
     4441 cagcttttat aacagactct gccaacttct cttggctacc ttctttatag taattggctg
     4501 ttactgtagc agtggttggc gcttcgcttt ctctataaac taaggtcact gttctacctt
     4561 cgcttacaat attcccagtt aaacttgcag aatttgtatc tgcttcttta aaa
//
LOCUS       DAVBCA010000089         4574 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.089, whole genome shotgun sequence.
ACCESSION   DAVBCA010000089 DAVBCA010000000
VERSION     DAVBCA010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4574)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4574)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4574
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.089"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            51..1596
                     /locus_tag="VQU19_001990"
     rRNA            51..1596
                     /locus_tag="VQU19_001990"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1648..1720
                     /locus_tag="VQU19_001991"
     tRNA            1648..1720
                     /locus_tag="VQU19_001991"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1681..1683,aa:Ala,seq:tgc)
     gene            1845..>4574
                     /locus_tag="VQU19_001992"
     rRNA            1845..>4574
                     /locus_tag="VQU19_001992"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT         1256 a          946 c         1367 g         1005 t
ORIGIN      
        1 gaaaaaaaca ataaatctgt cagtgacaga aatgagtgag aactcaaact tttaatgaga
       61 gtttgatcct ggctcaggac gaacgctggc ggcgtgccta atacatgcaa gtagaacgct
      121 gaaggaggag cttgcttctc tggatgagtt gcgaacgggt gagtaacgcg taggtaacct
      181 gcctggtagc gggggataac tattggaaac gatagctaat accgcataag agtagatgtt
      241 gcatgacatt tgcttaaaag gtgcacttgc atcactacca gatggacctg cgttgtatta
      301 gctagttggt ggggtaacgg ctcaccaagg cgacgataca tagccgacct gagagggtga
      361 tcggccacac tgggactgag acacggccca gactcctacg ggaggcagca gtagggaatc
      421 ttcggcaatg gacggaagtc tgaccgagca acgccgcgtg agtgaagaag gttttcggat
      481 cgtaaagctc tgttgtaaga gaagaacgag tgtgagagtg gaaagttcac actgtgacgg
      541 tatcttacca gaaagggacg gctaactacg tgccagcagc cgcggtaata cgtaggtccc
      601 gagcgttgtc cggatttatt gggcgtaaag cgagcgcagg cggttagata agtctgaagt
      661 taaaggctgt ggcttaacca tagtaggctt tggaaactgt ttaacttgag tgcaagaggg
      721 gagagtggaa ttccatgtgt agcggtgaaa tgcgtagata tatggaggaa caccggtggc
      781 gaaagcggct ctctggcttg taactgacgc tgaggctcga aagcgtgggg agcaaacagg
      841 attagatacc ctggtagtcc acgctgtaaa cgatgagtgc taggtgttag accctttccg
      901 gggtttagtg ccgtagctaa cgcattaagc actccgcctg gggagtacga ccgcaaggtt
      961 gaaactcaaa ggaattgacg ggggcccgca caagcggtgg agcatgtggt ttaattcgaa
     1021 gcaacgcgaa gaaccttacc aggtcttgac atccctctga ccgctctaga gatagagttt
     1081 tccttcggga cagaggtgac aggtggtgca tggttgtcgt cagctcgtgt cgtgagatgt
     1141 tgggttaagt cccgcaacga gcgcaacccc tattgttagt tgccatcatt tagttgggca
     1201 ctctagcgag actgccggta ataaaccgga ggaaggtggg gatgacgtca aatcatcatg
     1261 ccccttatga cctgggctac acacgtgcta caatggctgg tacaacgagt cgcaagccgg
     1321 tgacggcaag ctaatctctt aaagccagtc tcagttcgga ttgtaggctg caactcgcct
     1381 acatgaagtc ggaatcgcta gtaatcgcgg atcagcacgc cgcggtgaat acgttcccgg
     1441 gccttgtaca caccgcccgt cacaccacga gagtttgtaa cacccgaagt cggtgaggta
     1501 accgtaagga gccagccgcc taaggtggga tagatgattg gggtgaagtc gtaacaaggt
     1561 agccgtatcg gaaggtgcgg ctggatcacc tcctttctaa ggataaggaa ctgcgcattg
     1621 gtcttgttta gtcttgagag gtcttgtggg gccttagctc agctgggaga gcgcctgctt
     1681 tgcacgcagg aggtcagcgg ttcgatcccg ctaggctcca ttggtgagag atcaccaagt
     1741 aatgcacatt gaaaattgaa tatctatatc aaatagtaac aagaaaataa accgaaaacg
     1801 ctgtagtatt aataagagtt tatgactgaa aggtcagaaa ataaggttaa gttaataagg
     1861 gcgcacggtg gatgccttgg cactaggagc cgacgaagga cgtgacaaac gacgatatgc
     1921 cttgggtagc tgtaagtaag cgatgatcca gggatttccg aatgggggaa cccaacaggt
     1981 agtacctgtt acccacatct gttaaggatg tgaggaggaa gacgcagtga actgaaacat
     2041 ctaagtagct gcaggaagag aaagcaaaag cgattgcctt agtagcggcg agcgaaacgg
     2101 caggagggca aaccgaagag tttactcttc ggggttgtag gactgcaatg tggactcaaa
     2161 gattatagaa gaatgatttg ggaagatcag ccaaagagag taatagcctc gtatttaaaa
     2221 tagtctttgt acctagcagt atcctgagta cggcgggaca cgtgaaatcc cgtcggaatc
     2281 tgggaggacc atctcccaac cctaaatact ccctagtgac cgatagtgaa ccagtaccgt
     2341 gagggaaagg tgaaaagcac cccgggaggg gagtgaaata gaacctgaaa ccgtgtgcct
     2401 acaacaagtt cgagcccgtt aatgggtgag agcgtgcctt ttgtagaatg aaccggcgag
     2461 ttacgttatg atgcgaggtt aagttgaaga gacggagccg tagggaaacc gagtctgaat
     2521 agggcgcctt agtatcatga cgtagacccg aaaccatgtg acctacccat gagcaggttg
     2581 aaggtgcggt aagacgcact ggaggaccga accagggcac gttgaaaagt gcttggatga
     2641 cttgtgggta gcggagaaat tccaaacgaa cttggagata gctggttctc tccgaaatag
     2701 ctttagggct agcgtcgaca ttagagattc ttggaggtag agcactgttt gggtgagggg
     2761 tccatcccgg attaccaatc tcagataaac tccgaatgcc aatgaattat ggtcggcagt
     2821 cagactgcga gtgctaagat ccgtagtcga aagggaaaca gcccagacca ccagctaagg
     2881 tcccaaaata attgttaagt ggaaaaggat gtggggttgc acagacaact aggatgttag
     2941 cttagaagca gctattcatt caaagagtgc gtaatagctc actagtcgag tgaccctgcg
     3001 ccgaaaatgt accggggcta aaacaattta ccgaagctgt ggataccttt ataggtatgg
     3061 taggagagcg ttctatgtgt gatgaaggta taccgtgagg agtgctggaa cgcatagaag
     3121 tgagaatgcc ggtatgagta gcgaaagaca ggtgagaatc ctgtccaccg taagactaag
     3181 gtttccaggg gaaggctcgt ccgccctggg ttagtcggga cctaaggaga gaccgaaagg
     3241 tgtatccgat ggacaacagg ttgatattcc tgtactagag tatgtagtga tggagggacg
     3301 cagtaggcta actaaagcag acgattggaa gagtctgtct aagcagtgag gtgtgatatg
     3361 agtcaaatgc ttatatctgt aacattgagc tgtgatgggg agcgaagttt agtagcgaag
     3421 ttagtgacgt cacactgcca agaaaagctt ctagcgttta aacatactct acccgtaccg
     3481 caaaccgaca caggtagtcg aggcgagtag cctcaggtga gcgagagaac tctcgttaag
     3541 gaactcggca aaatgacccc gtaacttcgg gagaaggggt gctgacttta agtcagccgc
     3601 agtgaatagg cccaagcaac tgtttatcaa aaacacagct ctctgctaaa tcgtaagatg
     3661 atgtataggg ggtgacgcct gcccggtgct ggaaggttaa gaggagtgct tagcgtaagc
     3721 gaaggtatga attgaagccc cagtaaacgg cggccgtaac tataacggtc ctaaggtagc
     3781 gaaattcctt gtcgggtaag ttccgacccg cacgaaaggc gtaatgattt gggcactgtc
     3841 tcaacgagag actcggtgaa attttagtac ctgtgaagat gcaggttacc cgcgacagga
     3901 cggaaagacc ccatggagct ttactgcagt ttgatattga gtgtctgtac cacatgtaca
     3961 ggataggtag gagtctaaga gatcgggacg ccagtttcga aggagacgct gttgggatac
     4021 tacccttgtg ttatggccac tctaacccag ataggtgatc cctatcggag acagtgtctg
     4081 acgggcagtt tgactggggc ggtcgcctcc taaaaggtaa cggaggcgcc caaaggttcc
     4141 ctcagaatgg ttggaaatca ttcgcagagt gtaaaggtat aagggagctt gactgcgaga
     4201 gctacaactc gagcagggac gaaagtcggg cttagtgatc cggtggttcc gtatggaagg
     4261 gccatcgctc aacggataaa agctaccctg gggataacag gcttatctcc cccaagagtt
     4321 cacatcgacg gggaggtttg gcacctcgat gtcggctcgt cgcatcctgg ggctgtagtc
     4381 ggtcccaagg gttgggctgt tcgcccatta aagcggcacg cgagctgggt tcagaacgtc
     4441 gtgagacagt tcggtcccta tccgtcgcgg gcgtaggaaa tttgagagga tctgctccta
     4501 gtacgagagg accagagtgg acttaccgct ggtgtaccag ttgtcttgcc aaaggcatcg
     4561 ctgggtagct atgt
//
LOCUS       DAVBCA010000090         4538 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.090, whole genome shotgun sequence.
ACCESSION   DAVBCA010000090 DAVBCA010000000
VERSION     DAVBCA010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4538)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4538)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4538
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.090"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(87..1097)
                     /locus_tag="VQU19_001993"
     CDS             complement(87..1097)
                     /locus_tag="VQU19_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HET2481183.1"
                     /translation="MSFLSKNGAGILACLLISIVSWYLGGFFPVIGAPVFAIFIGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVVLLGFGLNISQVFAVGQSSLPVILSTISIALI
                     IAYLFQRFFALDTKLATLVGVGSSICGGSAIAATAPVIDAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNEGFALFAGTAVNDTSSVTAAASAWDSLYQSNTLESATIVKLT
                     RTLAIIPITLFLSYWQSRQQENKQSLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKELSKFLIVMAMSAIGLKTNLVAMVKSSGKSILLGAICWIAIILTTLGMQTLIG
                     IF"
     gene            1246..2415
                     /locus_tag="VQU19_001994"
     CDS             1246..2415
                     /locus_tag="VQU19_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET2481184.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQVISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPAAFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            2412..3182
                     /gene="recO"
                     /locus_tag="VQU19_001995"
     CDS             2412..3182
                     /gene="recO"
                     /locus_tag="VQU19_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HET2481185.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            3179..4171
                     /gene="plsX"
                     /locus_tag="VQU19_001996"
     CDS             3179..4171
                     /gene="plsX"
                     /locus_tag="VQU19_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HET2481186.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLRGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            4177..4410
                     /locus_tag="VQU19_001997"
     CDS             4177..4410
                     /locus_tag="VQU19_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HET2481187.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQSVGDVVKIIQGK"
     gene            4456..4538
                     /locus_tag="VQU19_001998"
                     /pseudo
     CDS             4456..4538
                     /locus_tag="VQU19_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
BASE COUNT         1325 a          862 c         1164 g         1187 t
ORIGIN      
        1 tgaggttgca gatagaactg acgaagtcag taacatatat acggcaaggc gacgttgacg
       61 tggtttgaag agattttcga agagtgttag aaaatgccga taagggtctg cataccaaga
      121 gtggtgagga tgatggcaat ccagcagatg gctccaagaa gaatggattt tccactggat
      181 ttgaccatag cgaccagatt ggttttgaga ccgatagcac tcatggccat gacaataagg
      241 aatttagaga gttctttgag aggggtaaag aaactactgg acacacctag agaggtgagt
      301 agtgtagtga ggagagaggc aaggataaag taaaggataa aaagtgggaa gacttttttc
      361 agttgtaggc tttgcttgtt ttcttgttgg cgactttgcc agtaggagag aaagagcgtg
      421 atagggataa tagccaaagt acgtgtgagt ttaacaatgg ttgcagactc gagggtattg
      481 ctttggtaaa gactgtccca agcgctggcg gcagccgtta cagaggaagt gtcgttgacc
      541 gcagtccctg caaagagggc gaagccttca ttggatagat gaagccaggt gccgagggtt
      601 ggaaagatga gcgcagccaa gacattgaag aaaaagataa cggaaatggc ttgggctact
      661 tccttttcct tagcatcaat aacgggcgct gtcgctgcaa tggcagaacc cccacagata
      721 gaagaaccta ctccaaccaa ggtagccagt tttgtatcca gtgcaaagaa acgctggaag
      781 aggtaggcaa taatcagagc tattgagata gtggacagga tgacagggag tgaagattgg
      841 ccaactgcga agacctgcga gatattgaga ccaaaaccaa gcaagacaac ggcatattgg
      901 agcaacttct tggaactaaa ggtcaaacca gcatccagtt gtttatagga cgagagaaag
      961 ggatgtagga gcatgcctat gaaaatggca aaaacgggcg cgccaatcac agggaagaat
     1021 cctcctaagt accaagatac gatagaaatg agaaggcagg ccaagatacc tgctccattt
     1081 tttgatagaa atgacataaa aacctccaaa taaaatctat taccattata gacctataaa
     1141 caggaaaagt aaaatagaaa gtggaaagct attctctaat gtatttttgc ggtcgggggg
     1201 cttttgtagt ataatagaga tacgttttga aagtaggagg tatctatgga cttaactaag
     1261 cgctttaata aacagttaga taaaattcaa gtttcgttga ttcgtcagtt tgaccaggtt
     1321 atttcggaga ttcctggggt cttgcgtttg accttggggg aacctgattt tacaacgcca
     1381 gaccatgtca aggaggcggc caagcgagcg attgatcaga accaatccta ctatacaggg
     1441 atgagtggtc tgctgactct acgtcaggca gccagtgact ttgttaagga aaagtaccaa
     1501 ctggactatg ctcctgaaaa tgaaattttg gttacaattg gggcgacaga ggctttatct
     1561 gcgactttga cggctatttt ggaagaggga gacaaggtac ttttgccagc tcctgcttat
     1621 ccaggctatg aaccgattgt taacttagtt ggggcagaaa ttgttgagat tgatacgact
     1681 gaaaatggtt ttgtcttgac tcctgagatg ttggagaagg ccattttgga gcagggtgat
     1741 aagctcaagg cggttattct caactatcca gccaatccga caggaattac ctacagtcga
     1801 gagcagttag aggccttggc agctgtttta cgcaagtacg aaatttttgt tgtctgtgat
     1861 gaggtttact cagaattgac ctacacaggc gaagcccatg tgtctctagg aacgatgttg
     1921 agagaccagg ctattattat caatggtttg tctaaatcgc atgccatgac aggttggcgt
     1981 ttggggctga ttttcgctcc tgcggccttc acagcccagt taatcaagag tcaccaatac
     2041 ttggtcactg ccgcaaatac catggcgcaa catgctgcgg tagaagcctt gacggctggt
     2101 aaaaatgatg cggagcccat gaagaaggaa tatatccaac gtcgggacta tatcatcgaa
     2161 aaaatgactg ctcttggttt tgagattatc aaaccagacg gtgccttcta tatttttgct
     2221 aaaattccag cgggctacaa tcaagactcc tttgcttttc tgaaggattt tgctcagaag
     2281 aaggccgttg cctttatccc tggtgcagcc tttggacgtt acggggaagg ctacgtccgc
     2341 ctatcttatg cagccagcat ggagactatc aaagaagcca tgaaacgact tgaggagtac
     2401 atgagagaag catgattcag tctatcacga gtcaaggctt ggtgctttac aatcgcaatt
     2461 ttcgtgagga tgacaagctc gtcaaaattt ttacagagca ggttggcaaa cgcatgtttt
     2521 ttgtcaaaca cgctggtcag tctaagctgg cgcctgttat tcagcccttg gtgctggcac
     2581 gatttctctt gcgaatcaat gatgacggac tcagttacat cgaagactat catgaggtca
     2641 tgacttttcc caagattaat agtgacctct ttgtcatggc ctatgcgacc tatgtggcag
     2701 ctcttgcaga tgctagtttg caggacaatc agcaggatgc tcccttgttt gcttttttgc
     2761 aaaagacttt ggagttgatg gaagcaggct tggattatca ggttttgacc aatatttttg
     2821 aaattcaaat tttgactcga tttggaatca gcctcaattt taatgagtgt gtcttctgcc
     2881 atcgggttgg tcaggctttt gacttttctt tcaaatatgg agcctgcctc tgtccagagc
     2941 attatcatga ggataagaga cgttgtcatc tcaatcccaa tatcccctat ctgctcaatc
     3001 aatttcaagc tattgatttt gagactttgg agaccatttc gctcaagcct ggaatcaagc
     3061 aagagctacg ccaatttatg gatcaattat atgaagagta cgttgggatt cacctaaaat
     3121 caaagaaatt tattgattcc ctagcagact ggggacaatt actaaaagag gaaaagaaat
     3181 gaaaaaaatc gcagtagatg ccatgggggg cgattacgca cctcaggcca ttgttgaggg
     3241 tgtcaatcaa gccctatctg acttttcaga tatcgaggtt caactttacg gagatgaagc
     3301 taaaatcaag caatatctga cagcgacaga gcgcgtcagc attatccata cggatgagaa
     3361 gattgattcg gatgatgaac ctacgagagc tattaggaat aagaaaaatg ccagtatggt
     3421 attggcagcc aaggctgtca aagatggtga agcagacgct gtcctttcgg ctgggaatac
     3481 aggtgccttg ttggcagcag gattcttcat cgtgggtcgt atcaagaata tcgaccgtcc
     3541 tggactcatg tctaccttgc ctaccgttga tggaaaaggt tttgacatgc tagaccttgg
     3601 tgccaatgca gaaaatacag cccagcacct ccatcaatat gcggttctag gttccttcta
     3661 tgctaaaaat gtccgtggca ttgcgcaacc acgcgttggt ttgctcaaca acggaacaga
     3721 gagtagcaag ggcgacccgc ttcgtaagga aacttatgaa ttactggcgg ctgatgaaag
     3781 tttgaacttt atcggaaacg tggaagcgcg tgatttgatg aatggcgttg cagatgttgt
     3841 tgtggcagat ggtttcacgg gaaacgctgt gctcaaatcc atcgaaggga cagctatggg
     3901 aatcatgggc ttgctcaaga cagctattac aggtggtggt cttcgagcga aactaggtgc
     3961 cctccttctc aaggacagcc tcagaggttt gaaaaaacag ctcaattatt cagatgttgg
     4021 tggagcggtc ttgtttggtg ttaaggcacc tgttgtcaag actcatggct caagcgatgc
     4081 caaggctgtt tatagtacga ttcgtcagat ccgtaccatg ctagaaacag acgtggttgc
     4141 ccagactgcg cgtgaatttt caggagaata aaagagatga cagaaaaaga aatttttgac
     4201 cgtattgtga ccattatcca agagcgacag ggagaggact ttgtcgtgac agaatccttg
     4261 agtctgaaag acgatttgga tgcggattct gttgacttga tggagtttat cttgactctg
     4321 gaagatgaat ttagtatcga aatcagcgat gaggaaattg accaactcca aagtgtagga
     4381 gatgtggtta aaatcattca aggaaaatag caatcggagt tccaagtcaa cggaagtaga
     4441 tggtttttag aaatgagaaa tatcggacaa gctggtaaaa tcttggctga cagtggttat
     4501 caagggctca tgaagatata tcctcaagca caaacttc
//
LOCUS       DAVBCA010000091         4518 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.091, whole genome shotgun sequence.
ACCESSION   DAVBCA010000091 DAVBCA010000000
VERSION     DAVBCA010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4518)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4518)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4518
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.091"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(112..549)
                     /locus_tag="VQU19_001999"
     CDS             complement(112..549)
                     /locus_tag="VQU19_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HET2481188.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(634..3267)
                     /gene="polA"
                     /locus_tag="VQU19_002000"
     CDS             complement(634..3267)
                     /gene="polA"
                     /locus_tag="VQU19_002000"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HET2481189.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVAEGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIVVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYMQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            3520..3873
                     /locus_tag="VQU19_002001"
     CDS             3520..3873
                     /locus_tag="VQU19_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HET2481190.1"
                     /translation="MILRHLGISPTNDLVAKKIFSNPEITCQFIRDMLDLPAKNVTIL
                     EGSNIHVLPSMPYSAQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINHLWAYLCSQV
                     NQNLEKIRQREGDTH"
     gene            4088..4204
                     /locus_tag="VQU19_002002"
     CDS             4088..4204
                     /locus_tag="VQU19_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HET2481191.1"
                     /translation="MVGVFRQQALYPATATSHYPSKSTAGLQELVRGGQENV"
     gene            4197..4430
                     /locus_tag="VQU19_002003"
     CDS             4197..4430
                     /locus_tag="VQU19_002003"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2481192.1"
                     /translation="MFSQLHMREEQVLLAQDYALETARAEGLEQGLERGKVEGRAERK
                     LFAFLDIVRQGLLTSEVASQQLGMSVSEFEALL"
BASE COUNT         1365 a         1091 c          833 g         1229 t
ORIGIN      
        1 gtatctacaa cctcaaaaca gtgttttgag cagcccgcga ctagtttcct agtttgctct
       61 ttgattttca ttgagtataa cacaaaaggt agcccatcag ctaccttttt cttatgcttc
      121 ctcaatcaag cgagtatgtt ctctcttgat acagcgattc atcacgatat catcacatcc
      181 accatcacgc aaaatctctt tcgcttctaa actttcaagt cctagctgtg cccaaaaaat
      241 cttggcatca gctttgagaa aatcacgcgc cacatcgggc agaaattcac tgcgacgata
      301 aacattgaca atatctacag gaaaaggaat ttcagcgagg ctagcataag ccttttcacc
      361 caagatttcg ccacctgccg ccttgggatt gactgggatg attttatagc cccgagcctg
      421 catttccttt gtcactcgat tgctggttgt ttcttcacgg tcagacaaac ccaccacagc
      481 aagggtttta ctcgttgcga gatactgacg aatcacgcca tcacttggat tgataaattc
      541 ttgactcata gaaaacctcc tttttcatca gtatagcaca ttttgaaaag gtttgcagaa
      601 ttctactaca aaaaaggagg actagccccc tttttattta gcctcgtacc aggttgcccc
      661 ttcattctca tctgcgataa gaggaacact gagttgaatg gcttcttcca tggtttgttt
      721 caccaatttt ttcatctcta ccaattcaga tttaggcact tcaaggacga tttcatcgtg
      781 cacttgtaac agcatcttag tctgataacc acctgcaacc aaggctttat ccagctgaat
      841 catggcaatc ttgagaatat ctgctgccga accctggata ggtgagttga tagcagttcg
      901 ctccgcaaaa ccacgaatat tgaagttgcg cgaattgata tctggcaact cacggcgacg
      961 cttaaagagg gtctctacat agcccttatc acgcgcctcc cgcaccactt catccatgta
     1021 gtttttaata cctggaaaac gttcaaagta ggtatcaatg taggctttgg cttccttacg
     1081 actaattccc aaattattag acaagccaaa gtctgaaatc ccataaacca ctccaaagtt
     1141 aactgccttg gcattgcgac gatcatttgc agtcacatta tcaggacgct caatgccaaa
     1201 gacccgcatg gctgtcgaag tatggatatc tgccccctct tggaaggcct taatcaagtg
     1261 ctcatcctta gaaatatgcg ccaaaacgcg caattcaatc tgtgaatagt cagagctgag
     1321 tagcacacta tcctcccact ctggcacaaa agccttccga atcaagcgcc cttgttccaa
     1381 tcgggcagga atattttgca agtttggatc cacactagac aaacgcccgg tctgggtcaa
     1441 atcctgcata tagcgagtat gaatctttcc atcagccaaa atccagtcct gcaagccaat
     1501 tacataagta gattgaatct tagcaatttg acggtaatcc aggattttct taacaatcgg
     1561 agcaatagga gcgagacgct ccaacacatc cactgctgtc gaataacctg tcttggtttt
     1621 cttagtgtat tctagaggaa gtcccaattt ctcaaagaga agcacgccca actgcttagg
     1681 cgagttgaca ttaaactcct caccagccag ctcgtaaatc tcttgagtca gtttttcaat
     1741 gacaagctca ttttcagcct gcatctcaag caaggtctct ttcttgacca caatcccagc
     1801 aatttccatc ttggcaagaa caaaagccag aggttgctcc atatcataaa gaagctctaa
     1861 ttgcccattt tcgctgagtt tttcaagtaa aataggctct gtttctacca aaacagcaag
     1921 tttacaagct aagtgttcca agaatttctc acgttcagga atggcctttt taacaccctt
     1981 accgtagaaa gtttcatcat caaccaagta agtctgacca taaagactag cgatggtcgc
     2041 aatttcattg tcctccacag tcgaaaggag gtatttagcc aaacggatgt caaaagcagg
     2101 cgcctgcaaa tccacaccaa aacgttgcaa aagaacttta accttcttaa agtcataaac
     2161 tctcagagat gttttttcta agaaatcctt gaaaatcggg tcttgcaaca gctcaagctt
     2221 gtctgtggca tagagcttat ccccacaaga ccaggcaaat ccaaccaaat tatccgtatg
     2281 ataattctca ccaaaaagct caaagtggaa gatagactct tcactcagca tatcttgact
     2341 gatttggtca acaatagtaa aatccaaacc ctcagccaca tcagctgacg acacatttaa
     2401 agcctgcttg agctgtttga atcccatctc atcgtaaaat ttcccaagat tttcaacatc
     2461 tggaccacta tagaccaagt cctctaaacc aatcgcaatc ggtgccttgg tatcaatggt
     2521 cgctagtgtt ttagacaaaa aggcctgttc cttgtcattg atgagatttt ccttcatctt
     2581 agaagtcttc attccatcaa tattttcata aatcccctca agcgaaccat gctccagcaa
     2641 gagcttaata cccgtctttt caccgacttt ggtcacccca gggatattat ccgacttatc
     2701 acccatgagc gccttgagat cgataaactg agctggtgtg aggcccattt cttccatgag
     2761 gtaatctggc gtaaaggcct caaactcagc cacacctttc ttggaaattt caaccaccgt
     2821 atgctcatcc gtcagctgaa tcaaatcctt gtccccactg acaatggtaa tatcaaaacc
     2881 atcctgctct gctagcttat ccaacgtccc aatgatgtca tccgcctcat actgagccag
     2941 ctcatagtga cgaatcccca tatgatccag caactcacga atgaaaggaa attgctcacg
     3001 aaactcatca ggagtcttgg cccgaccacc cttatagtcc gcatacatct ctgtccggaa
     3061 ggtcgtcttt cccgcatcaa aagccaccaa aatatgactc ggctcaaccc gctccaacaa
     3121 atgactcaac atcaactgaa aaccataaat cgcattggta tgcaaaccag ccgcattctt
     3181 aaaacggtcc aactgctgat acagcgcaaa aaacgcccga aaagctacag aagacccatc
     3241 aatcaataat aattttttct tatccataca cccattataa aggaaagaat caaaaaatac
     3301 cattgggaag agctagagca agtatttttc aaactttttc cgaataaata gatagagcca
     3361 gagaatttag taaacctaga tttaaaaatg tgctataata tagtatattg aatctataat
     3421 agtacacctt gactgctaaa atatttctat aaattaattt gactttcctg atagagttgt
     3481 tcacatctta tttcaattca ctatagaagg aggaaaagga tgattctcag acatctggga
     3541 attagcccga ccaatgactt ggttgctaag aaaattttca gcaacccaga aatcacttgt
     3601 caatttatcc gcgatatgct ggacttgcca gccaaaaatg tgactatttt ggagggaagt
     3661 aacattcatg tcttgccttc catgccctac tcagcgcagg atttttatac cagtatagac
     3721 gtcttggcgg agttggataa cggtactcaa gtaattattg agattcaagt ccatcatcag
     3781 aattttttca tcaatcactt gtgggcttac ctgtgcagtc aggttaatca aaatcttgaa
     3841 aaaattcgtc agcgagaagg tgatactcac tagatctaca aacacatcgc tcctgtttac
     3901 gtcattgcta tcgtggatag taattatttc tcagatgacc tggcttttca tagctttagt
     3961 atgcgcgaag acacaacagg tgaggtattg gcgattacca acaatggaca ggaaaaccat
     4021 ctggttaaga tggcattctt ggaattaaaa aatacagaga aaccagcaaa gacaaggttc
     4081 gcaagccatg gttggagttt ttcggcaaca agccctttac ccagcaaccg caacgagcca
     4141 ttacccaagc aaatcaactg ctggactaca agagctggtc cgaggaggac aggaaaatgt
     4201 ttagtcaact acatatgcga gaagaacaag tcttgttagc acaggactat gccttggaaa
     4261 ctgctagggc tgaaggcctt gaacaaggac tagagcgtgg gaaagttgaa ggaagggcag
     4321 aaaggaaact ttttgccttc ctagacatag tacgccaagg tcttctgact tctgaggttg
     4381 ccagccagca attaggtatg tcagtatctg aatttgaggc actgttgtaa aatggctcca
     4441 taatatccat agtgggtaaa tcccctatgg atattatgga gcctattttt gtgtagaaaa
     4501 aaagtcccat atgaccta
//
LOCUS       DAVBCA010000092         4438 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.092, whole genome shotgun sequence.
ACCESSION   DAVBCA010000092 DAVBCA010000000
VERSION     DAVBCA010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4438
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.092"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..119
                     /locus_tag="VQU19_002004"
     CDS             <1..119
                     /locus_tag="VQU19_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2481193.1"
                     /translation="QQGFTDRLVGYSSSIALVFTTLIGMISLVQRRVLKEDD"
     gene            121..966
                     /locus_tag="VQU19_002005"
     CDS             121..966
                     /locus_tag="VQU19_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET2481194.1"
                     /translation="MKRFKPTTILEYILLTLLAGLFLFPMVWMVVSAMKPEADVYKNL
                     TSWQAFLPSLNPADWFKPYQEVFERFSIFTYLGNSIFYAGTFAIGSIIVNALAGFAFA
                     KVNFSGKKILFGFLLALLIIPVETVLIPQFTIINSLGLVNNRLAVIIPGLASVFNIYL
                     FRNFFIAIPEEILESAKMDGASIVRIFFRIMLPMSKPAVATVGVLSFISSWNDYIWPL
                     MVLTDSSKFSMQVAITTINTTQPVYINQVMAVLTISTIPLILVYVVAQKYIVQGLGGS
                     GTGIK"
     gene            976..2295
                     /locus_tag="VQU19_002006"
     CDS             976..2295
                     /locus_tag="VQU19_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HET2481195.1"
                     /translation="MINKTFTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEETGVRQVQNMAFSDDGIHFEKISQNPVATGSDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKDNVGCIVLLGSDNLVEWQFESIFLKGGEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWREKRFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDTDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(2503..2575)
                     /locus_tag="VQU19_002007"
     tRNA            complement(2503..2575)
                     /locus_tag="VQU19_002007"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2540..2542),aa:Lys,seq:ctt)
     gene            complement(2839..4110)
                     /locus_tag="VQU19_002008"
     CDS             complement(2839..4110)
                     /locus_tag="VQU19_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HET2481196.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYAARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQRIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWIKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDRLRKI"
BASE COUNT         1294 a          809 c          976 g         1359 t
ORIGIN      
        1 atcaacaagg ttttactgat cgtcttgtag gatattctag ctcaatcgct ttagtattta
       61 caacgttaat tggtatgatt agcttagtac aacgtcgcgt tctgaaggag gatgactaag
      121 atgaaacgat ttaaaccaac aacaatctta gaatatattc tgttaacttt attggcagga
      181 ctcttccttt ttcctatggt ttggatggta gtttcagcta tgaagccaga agcggatgtt
      241 tataaaaatt tgactagttg gcaagccttc ttaccaagtt taaatcccgc tgattggttt
      301 aaaccttatc aggaagtatt tgagcgcttt agtattttta catatctagg gaacagcatt
      361 ttttatgctg gaacgtttgc tattggttct attattgtca atgcactggc cggtttcgct
      421 tttgcaaaag tcaatttttc aggtaagaaa attttatttg gtttcttact tgctttactt
      481 attattccag tggaaactgt gttaattcca caatttacca ttatcaattc cttaggtttg
      541 gtcaataatc gtcttgcagt tattattcca ggattggcga gtgtatttaa tatttactta
      601 tttaggaatt tctttattgc aattccagaa gagattcttg agtctgcaaa gatggacgga
      661 gcaagtatcg ttagaatttt ctttagaatt atgcttccaa tgtctaaacc tgcagttgct
      721 acagttggtg ttttatcatt tatttcaagc tggaatgatt atatctggcc attgatggtt
      781 ttgacagatt cttctaaatt ttcaatgcag gttgcaatta caactattaa tacaactcaa
      841 ccagtttata tcaatcaggt aatggctgta ttaactattt caacgattcc gttgattttg
      901 gtctatgtag tcgctcagaa atatattgtt caaggtctgg gtggttccgg aactggaata
      961 aaataggata tacttatgat aaataaaaca tttacagtag aaaaagccaa tcgttttata
     1021 gcagaaaata aacatctcgt taatactcaa tataagcctg aagaacattt ttcagctgag
     1081 attggttgga tcaatgatcc aaatggattt gtctattttc gtggagaata ccatctcttt
     1141 tatcaattct atccatatga tagtgtttgg gggcctatgc actggggaca tgctaaaagt
     1201 aaggacttgg tgacttggga gcacttgcca gtggcacttg ctcctgacca agattatgac
     1261 cgaaatggtt gtttctcagg ctctgccatt gtcaaggatg atcgcctctg gctcatgtac
     1321 actggacata tcgaagaaga aaccggtgtc cgccaagtgc aaaatatggc attttcagat
     1381 gacgggattc actttgaaaa gatttcccaa aatccagttg caactggatc agacttgcca
     1441 gatgagttga ttgctgctga tttccgtgat ccaaaactct ttgaaaaaga tggacgctat
     1501 tactccgtag tagctgccaa acacaaggat aatgtgggct gtatcgttct actagggtcc
     1561 gataacctag tagaatggca gttcgaatcc atctttttaa aaggaggaga acaccaaggc
     1621 tttatgtggg aatgcccaga ttacttcgag ttagatggga aagattgcct tattatgtca
     1681 cccatgcgtt atcagcgtga gggagactca tatcataaca tcaactcatc gcttttgttc
     1741 acgggtaagg tagattggag agaaaaacgt tttatcccag aatcagttca agaaattgat
     1801 catggccaag acttctatgc gcctcaaaca ttgttggacg atcaaaatcg tcgtatcctg
     1861 attgcttgga tgcagacatg ggggcgtacc cttccaaccc atgaccaaga acacaaatgg
     1921 gcatgtgcca tgactttacc tagaattcta agattggaag atggcaaact aagacaattc
     1981 cctgttaaaa aaggccaata tcaaatccaa atagataaag attgtcatta ccacttagga
     2041 aatgatacag attatcttga atttggttat gacagtaatg cgcagcaagt ttacattgat
     2101 cgtagccatc ttattcaaaa aattctaggt gaagaagaac aggacactag tcgacggtat
     2161 gtagatattg aagctaaaga attggaagtt gttctagata aaaattccat cgagattttt
     2221 gtcaatcaag gtgaagcaag cttgactgca acttattact taacggtgcc agctgagcta
     2281 tcacgaattg attaaaaatt aagttatttc tcctaaagaa aaagttctct ttctaaaata
     2341 gtggaaagag gactttttgt gttttgggta tataagctta gtttatggta tttgtaaaat
     2401 tggtgttgga ttatgattta agctagtttt ctaaagaatt tgaaaaaaat tttatttaag
     2461 caaaaaaacc ttggttccaa ggcttttcct gttgtattta gatgccccct acagggatcg
     2521 aacctgtgac ccacggatta agagtccgct gctctgccag ctgagctaag gaggcaaaga
     2581 aaaagctgta ttggtgccga aacttcacgg tttgtattga acccgcgcaa ttaagcaggt
     2641 gggcaactcg ctctaactga agctgtttcc gtgtgagacg gcctacatgc tgttagaaga
     2701 cttttgtttc cctaataata caaaaaatag tcggtcaaca cttaagtgtg aagtcgtaca
     2761 ccacagcgtt tctatactta tatgatacca ctttttcaaa aaaaatcaag aggaaagtgc
     2821 aattttttga aaaggatttc agatttttcg caaacgatcg atagcttcct ttctttgagc
     2881 caaagcccgt tcatatttac cagtatcttc tgcttggaaa tagtgatgat tacgaatttt
     2941 ttctggcaga tagtcttgct tgatccaatt tccaggatag ttgtgtggat agagatagtc
     3001 ttgggcattc cccagttcct tgcttccact gtagtgccca tcacgcaggt gtcgcggaat
     3061 aggcaagtgc cctgatgttt tgaggtcagc aagtgcctta tccatagcta cataggctga
     3121 gttggatttt ggagaaaggg ccaaatcaat cacgacattg gcaatgagaa tgcgggcttc
     3181 ggggaaacca atcctttgtg cagcatccag agcagtcacg gtatgaatct gggcctcagg
     3241 attggctaag ccaatatctt cataggcgat aacagtcaag cgacgagcga gactaggcag
     3301 atccccagcc tcaatcaagc gggcagcata gtggagactg gcatccacat ctgagccacg
     3361 gatagacttt tgcagggcag atagaacatc atagtgaccg tctccatcct tgtccatagt
     3421 gatgtagctt ctctgaagac tattttccat gatgtctaag gtgatgtggc gaatgccctc
     3481 gtcattctca ggggtagaga gaacagccaa gtccagtgag ttaaaggcag agcgaaggtc
     3541 tccgtttgta gaggttgcga tgaaatccag cgcatcctca tctagttcta ttggaaaatc
     3601 aaaaccacgt tcagggttac ttagagctat ctgcagggcc tctttgacgt cttggttaga
     3661 cagaggttcc aactcgaaaa tttgaacacg gctacgaatg gcaggagtga cagagaagaa
     3721 aggattttca gtcgttgctc caatcatgat gaccagtcca ctttccaaga gaggcaagag
     3781 gaagtcttgc ttggtcttat ctagtcgatg aatttcgtct agcaatagga cgagaccacc
     3841 agaaaattta gcttcttccg agatttcttg cagtcgcttt ttactatcaa ctgtcgcatt
     3901 gaaagttcga aaggcatact tggtcgttcc agcgatggca gaggcaatac tggttttgcc
     3961 gattccagga gggccatata gaatcatgga ggacaggcgg ttggcttcca ccatgcggcg
     4021 gatgattttt ccaggtccga ccagatgctc ctgaccgatg acctggtcga tggttttagg
     4081 gcgcatgcga agcgcgagat tgtctggcat agcagtcctt tctaacgtgg atttgagtag
     4141 aatgactcat ctactatatc ttactatgtc cattctagcc tattagttgt gatatttcaa
     4201 tggttttgta ataatcaggg agtgagatag aatctttttt actatttaat ttaatgagga
     4261 gaggtatcag catgagagat ttgattttcc ttaaagctca aaataggata gttgagccta
     4321 aagaagtgga agtgctgact tgagaaataa tattgctgaa tgtcattgta tgaactataa
     4381 tgaaaagaga ggtgataagc aatggaaatg atggaccaag tcaggaaatt ttgatttt
//
LOCUS       DAVBCA010000093         4213 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.093, whole genome shotgun sequence.
ACCESSION   DAVBCA010000093 DAVBCA010000000
VERSION     DAVBCA010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4213)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4213)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4213
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.093"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(61..234)
                     /locus_tag="VQU19_002009"
     CDS             complement(61..234)
                     /locus_tag="VQU19_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HET2481197.1"
                     /translation="MNIKKRVLSAGLTFASVLLLAACGQSGSDTKTYSSTFSGNPTTF
                     NYLLDYYTDNIVN"
     gene            complement(392..1999)
                     /locus_tag="VQU19_002010"
     CDS             complement(392..1999)
                     /locus_tag="VQU19_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HET2481198.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGIGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIAAIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENPNSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDLLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLVRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTLAQEVFEKQILVPWDAFCVELL"
     gene            2152..3636
                     /locus_tag="VQU19_002011"
     CDS             2152..3636
                     /locus_tag="VQU19_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HET2481199.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFLNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGISPADRKVAVVARQKAEETGGPALALELPNGDIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            3731..4213
                     /locus_tag="VQU19_002012"
     CDS             3731..4213
                     /locus_tag="VQU19_002012"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HET2481200.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
BASE COUNT         1220 a          963 c          803 g         1227 t
ORIGIN      
        1 tcaaaaaggt attaccaagt tgcaatacct tttatgaggc tcttttgtct tgttcttgtt
       61 tcaattgact atattatcag tgtaatagtc taatagatag ttaaatgtag ttggatttcc
      121 actaaaggtt gatgagtaag tttttgtatc tgaacctgat tggccgcaag cagctaaaag
      181 caaaacagat gcaaaagtca ggcctgcact aaggacacgc ttctttatgt tcatcttctt
      241 tctccttaat agtgggaatt tgtaaagtta attgaatttc gagaatgaaa gtttataaac
      301 cttggttata aaaaacaaag gatttctgct tttatacagt cctcccttgt ttttatatga
      361 tttcaatttt aaatttttct gcaaaaaata tttatagtaa ttccacacag aaagcatccc
      421 atggaactaa gatttgtttt tcaaagactt cttgagctag ggtgttttca atcaagacag
      481 atttgacttt tccttctact gtcaagtctt gctcttcatt ggacaagtta gccacaacta
      541 ggaagcgacg gtcgccatcc ttacgtatat aagcaaagac cttatcagcc gtatcaagca
      601 attcaaagtc agctcgaact agccagctat tctccttgcg aatttggacc agtttctgat
      661 aggtatagaa aatagaatct ggatttgcca gcgcttcttg gacattgatc atctcgtaat
      721 ttggattaac cgccaaccaa ggttgacctg ttgagaaacc agcgtttttg ctctcgtccc
      781 attgcatagg ggtacgggca ttgtcacgtc caataacacg gatactgtcc atgatttctt
      841 caatcggaac acctttttca agagcctcac gcgcatagtt gagagattca atatcttcta
      901 cttgatccag tgtttcaaac ggatagttgg tcatcccaat ctcctcacct tggtagatat
      961 aaggagttcc tctcataaga tgaagcaaga ttgcaaaggc tttggcagat ttttcgcggt
     1021 attcttggtc atttccccag attgagacaa tacgagggag gtcatggttg ttccagaaga
     1081 gggaattcca gccgtcctca actcctaact ctgtctgcca tttgttgaag atttctttta
     1141 acttagcgat attcagctct ttttgatagt gccatttagg ctgaccttcc tgatactgaa
     1201 gaccgatatg ttcaaactgg aagaccatag acaattcttg cccctttgga tcagagtaga
     1261 gcttggcaat ctctggcgtt gctccccaag tctcccctac tgtcaagaga tccttatctc
     1321 caaaggtcgc ctgattcatt tccttgagat agggatggag cataggacca ttattgacta
     1381 ccttctcgtc aggaattttg ccaatcatgt caataacatc catacggaaa ccaccaatac
     1441 ccttatcaat ccagaagttc atcatctcat aaattttctg gcgaagtttt tcattttccc
     1501 agttgagatc cggctgtttc ttgctgaaaa agtggagata gtattgacct gacttttcat
     1561 cgtattccca agcagaccca ctaaagatag aatctaaatc gttaggctca tcccgccaga
     1621 tatagtagtc tcgctcaggg ctattaggat tttcacaggc ctctacaaac caggcatgct
     1681 catccgaggt atgattgacc accaagtcca tgatgatacg gatatcacgc ttcttagctt
     1741 ctgcaatcag ctgatccatg tcctccatgg ttccaaaaat agccgcaatc gcttgataat
     1801 cagcaatatc gtagccatta tcatccatag ggctgtcata aacgggagaa agccaaattg
     1861 ctgtgattcc tagcttggct agatagtcca acttactggt aattcctggc aaatcgccaa
     1921 ttccatctcc attactatcc ataaaactct ttggatagac ttgatagact acggcattat
     1981 gccaccattt ttcttgcatc tgtttacctc attattttca taatctatag tctatgatag
     2041 cactttttaa aattttgtgc aagcgtttgc ttaatctttt taatttcttt tttagctccg
     2101 tagtttccta acttccaatt ttttattata atagagtcca gaggtaaaaa aatgaaaaaa
     2161 caagctttta gttctgaaca gtatttgaat ttacaacgcg accatatttt ggagcgcatt
     2221 aaccaatttg acggcaagct ctacttagag tttggcggta aaatgttaga agatttccac
     2281 gctgctcgtg tccttcctgg ttatgaacct gacaacaaaa tcaagctctt gcaagaattg
     2341 aaagagcagg ttgaggttgt gattgccatt aatgctagca acattgaaca ttccaaagca
     2401 cgtggcgact tgggcatttc ttatgaccaa gaagttcttc gtttgattga caaattcaat
     2461 gaattaggga tttttgttgg ttccgttgtc attacacaat acgctggcca acccgctgca
     2521 gatgccttcc tcaaccaact tgagaaaaac ggaattgatt cttatcttca ttatccaatc
     2581 aaaggatatc cgacggatat ggatcacatc atttccccag aaggcatggg caaaaacgac
     2641 tacatcaaaa ccagtcgcaa cttgattgtc gtaaccgctc ctggacccgg ttctggaaaa
     2701 ttggcaacgt gtatgtccaa tatgtaccac gaccaaatca atggcatcaa gtctggctac
     2761 gctaaatttg aaaccttccc tgtttggaat cttccccttc atcatccagt taacttggct
     2821 tatgaagctg ccacagctga ccttgatgat gtcaacatga ttgacccctt ccatcttcaa
     2881 acctatggag aaaccactgt caactacaac cgtgatatcg aaatcttccc agtgctcaag
     2941 cgcatgttgg aacgtattct cggaaaatca ccatacgctt caccgacaga tatgggtgtc
     3001 aacatggttg gtttcgctat tacagatgac gaggctgctg tcgaagcttc taaacaagaa
     3061 atcatccgcc gttactatca aacagttctt gacttcaaag ctgaaaaagt tggcgaagct
     3121 gccgtcaaga aaattgagtt gctcatgaac gacctcggta tctcacctgc agaccgtaag
     3181 gttgctgtcg ttgcgcgcca aaaagcagaa gaaactggcg gaccagccct agctcttgaa
     3241 ttaccaaatg gtgacattgt cactggtaaa aactcagaac tctttggccc tacagccgct
     3301 gccttgatca acgccatcaa aaaatcagct gacatcgcta aagaagtaaa actaatcgag
     3361 cctgaagttg ttaagccaat ccaaggactt aaaatcgatc atctcggtag ccgcaatcca
     3421 cgccttcatt caaatgaaat cctgattgca cttgctatca cagctacaga aaatcctgat
     3481 gctgcccgcg ctatggaaga actcggcaac ctcaaaggaa gcgaagccca ctcaaccatc
     3541 atcttgactg atgaagacaa gaatgtcctt cgtaaactgg gtatcaacgt aacctttgac
     3601 ccatactacc aatacgaccg cttatatcgt aagtaaagat ttcaacctct ccagcctcgg
     3661 agaggttttc tctctgtctc aggagcaagc tttatgatat aatgagagaa gaaaactgaa
     3721 aggatttacc atgtcaaaag aagttattgt cgaaagtttt gaacttgacc acaccattgt
     3781 caaagcaccc tatgttcgct tgattgggga agaaacagga ccaaaaggag acatcatctc
     3841 caattatgat attcgcttgg tgcaaccaaa cgaagactct atccctactg ccggccttca
     3901 cactatcgag cacctcttag ccaaactcat ccgtacccgc attgacggca tgattgactg
     3961 ttcaccattt ggttgccgca caggcttcca catgattatg tggggacgtc acaccagtgc
     4021 taaaatcgca gctgttatca aggattcgct caaggaaatc gctgaaacta ctacttggga
     4081 agatgtccca gggacaacca tcgaatcttg cggaaactac aaggaccaca gcctcttctc
     4141 tgctaaagaa tgggcaaaac tcatcttgga acaagggatt tcagatgatg cctttgaacg
     4201 tcatgtgatt taa
//
LOCUS       DAVBCA010000094         4116 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.094, whole genome shotgun sequence.
ACCESSION   DAVBCA010000094 DAVBCA010000000
VERSION     DAVBCA010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4116)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4116)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4116
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.094"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..776
                     /locus_tag="VQU19_002013"
     CDS             <1..776
                     /locus_tag="VQU19_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000603792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2481201.1"
                     /translation="DYSIVEEKLDWQSKLSKIYPNVEFIKIEKLKLILLCKYRNQIID
                     LEDDKKRLLLLKLLYLTSKQFCYDEFKGAKFGCMSFFSHYQGYMSRLDSLDSDKFVSV
                     KQRIVSSISKLVEQYSDHIINLDRTLVDSLSDTLENQLFDDWDYILSEITTYSELLAK
                     SGLLYNSLDYKIDNVKKEVAKLSDFHQSLFKIEGFSDFFDSWQFQRYRSLVNQVYEIF
                     SMLQVSSVERTVLCGALSTIVFSKSNFNYQAFFEYLKDT"
     gene            805..1713
                     /locus_tag="VQU19_002014"
     CDS             805..1713
                     /locus_tag="VQU19_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000386786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2481202.1"
                     /translation="MDYVDVILDEYGSVFLIKDHIKLKINNLELYRYFSSFGMSHLQF
                     RKEELPGKLKQFDFEKNKSDSYFSKKSSLIDFIKRNYFYDIKLYSDNPKNPIESWKNK
                     TEKIKIAKSTEILWSEVANFSSISKSPYYCLLYNLKNTENYILIISKTYFSAIQKMVS
                     YNLNNYFELEDVCCKSIVSKRELIENSININKSKMKLLNVCEGSKGYTRRVFKYNNIF
                     VGQLEFHSNIIFSEIALNELSIVKLLDSVESVLSEQLFGKLNWDNLFVVLSDDFNDYL
                     DINESQKYYSNGSLRGLELGIFMGGV"
     gene            1715..3613
                     /locus_tag="VQU19_002015"
     CDS             1715..3613
                     /locus_tag="VQU19_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcaO-like family protein"
                     /protein_id="HET2481203.1"
                     /translation="MRIIEIVDVEDQLLQLLSAHTNIDIRAQELSTLDPDSKVDLIIY
                     LKSRRDIENINNIIIKSPNRNIIVIISAFDIIYALYFPKSTFRPCLNCLLLKLKDNNP
                     EHNLLLFLKYGTLPSKHFNLDNRLKSNLILFNEKLDPKVEEYSIEGVNTTNFTFHFSC
                     SCENSGYDMSERMADILLGEGKKLSPKNYRLKKSEHLFDFTRYLDRNFGFFHHSYDEK
                     ISEYAPLHAVEINVDAGYESGWGRTFMTEAATKSAFLESLERYCNSRNRRYKKLIRGC
                     FSDLSKKYNTLNPVDFCLSNKEYRDSSYKFHDFDSEKNYDWIFGKNITTGKICLLPSQ
                     LVFYKDFSKSEENERFVYETSNGCALGSSIEEAIFYGILEIIERDNFLLTWYLKEEVK
                     QLSWESLPSRLRIINERLKEDNCELKLFNITKEVGIPVIWALYINHNENASIRSFSAA
                     GCHINPLSAIESAIFEVITSVPTFERLIEVRNKESFIEEIQNNFSLIRDIDDHILYHA
                     HADYKNKMPFLFKNNYSEYQNEFDENRIFNTYSHATLTSDLQALIKIIEKKFGDIYVV
                     NISDKVSEKFGLYCVKVLIPGLLNMSFGHSNRRVNIERIKNYVDYRGGNVNSITLNSI
                     NHLPHPFP"
     gene            3637..>4116
                     /locus_tag="VQU19_002016"
     CDS             3637..>4116
                     /locus_tag="VQU19_002016"
                     /inference="COORDINATES: protein motif:HMM:NF025394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiopeptide-type bacteriocin biosynthesis
                     protein"
                     /protein_id="HET2481204.1"
                     /translation="MKRDWKSKHLFYHDVQQFDKLVIYLSKFMDKLVNQNQIEKYFYI
                     RYWEGGPHIRLRYLVRDTQNFETIDSMINKYAYKFWENNPPMKLLNKTDYKKIYNESI
                     DNNGKMDRKLRKNATIENIAYIPEIERYGGEEALIVSEDLFCICSQVSTALLNVVDNY
                     "
BASE COUNT         1539 a          443 c          712 g         1422 t
ORIGIN      
        1 cagattactc aatagtggaa gaaaaattag attggcaaag taaattatct aaaatttatc
       61 cgaatgttga atttataaaa attgaaaaat taaaattgat tttgttgtgt aaatatagaa
      121 atcaaattat tgacttagag gatgataaaa aaagattgtt actattgaaa ttattatatt
      181 tgacttcaaa gcaattttgc tatgatgaat ttaaaggagc gaaatttgga tgtatgtcat
      241 ttttttcaca ttatcaaggt tatatgagca gattagattc actcgactca gataaatttg
      301 tttcggttaa acagaggatt gtttcctcta tttctaaatt agttgagcaa tattcagatc
      361 atattataaa tctggataga actttagttg attctctaag tgataccctt gagaatcagc
      421 tatttgatga ttgggattat atattaagcg aaataactac atatagcgaa ttattagcaa
      481 aatcaggatt gttatataat tcgctagact ataagattga taatgtaaaa aaagaagtgg
      541 ccaagctaag tgactttcac caatctttat ttaaaattga aggattttca gatttttttg
      601 atagttggca atttcaaaga tataggtctc tcgtgaacca agtttatgaa attttttcaa
      661 tgttacaagt aagtagtgta gaaagaactg tgttgtgcgg agctctaagt actattgtct
      721 ttagtaagtc aaattttaac tatcaagctt tttttgagta tctaaaagat acgtagaatt
      781 cgattttaaa ggaggctgaa atatatggat tatgtagatg taatattgga tgagtatggg
      841 agtgtttttc tgataaagga tcacataaaa ctaaaaatta ataatctaga actatatcgg
      901 tattttagta gctttggaat gagtcatctt caatttagaa aagaagagct tccaggaaaa
      961 ttaaagcagt ttgattttga aaaaaataaa agtgacagtt atttttctaa gaaaagtagt
     1021 ctgattgatt ttattaagag aaattatttt tatgatatta agttatattc tgataatccg
     1081 aaaaatccga tagagtcttg gaaaaataag acagaaaaaa ttaagattgc taaaagtaca
     1141 gaaattcttt ggagtgaagt agcaaatttt tcgtcaattt ctaaatctcc ttactattgc
     1201 ttgttatata atttaaagaa tactgaaaat tacatattga taatcagtaa gacatatttt
     1261 tcagccatcc aaaaaatggt ttcgtataat ctaaataatt attttgaatt agaagatgtt
     1321 tgttgtaaaa gcatagtgag caagcgagaa ttgatagaaa attcaattaa tattaacaaa
     1381 agcaaaatga aactgctaaa tgtttgcgaa ggtagtaaag gttacacaag aagagtattt
     1441 aagtacaata atatttttgt gggacaattg gaatttcact ctaacataat cttttcagaa
     1501 attgctttaa atgaattaag tattgttaag cttttagatt ctgttgaaag tgttttatct
     1561 gagcaactat ttggaaaatt aaattgggat aatttatttg ttgttttatc agatgatttt
     1621 aatgattatc tggatataaa tgaatctcaa aaatactact caaatggttc tttgagagga
     1681 ctggagcttg gaatctttat gggaggggtt taaaatgaga ataattgaaa ttgttgatgt
     1741 tgaggaccaa cttttacaac ttttaagtgc acataccaat attgatatta gagcacaaga
     1801 gttatcaaca cttgacccag attcaaaagt tgatttgatc atatacttga aatctcgacg
     1861 tgatattgaa aacataaata atattattat taaatcacct aacaggaata tcattgttat
     1921 aataagtgct tttgatatta tatatgcatt gtattttcca aaatcaacat ttagaccttg
     1981 tttgaactgt ctattattaa aacttaaaga taacaaccct gagcataatc tattattatt
     2041 cctgaaatac ggaacattac ctagtaaaca ttttaatctt gataataggt taaaatcaaa
     2101 tttaatacta tttaatgaga agttagaccc taaggtagag gagtatagta ttgagggggt
     2161 aaatactaca aattttactt tccattttag ttgtagctgt gaaaatagtg gttacgatat
     2221 gtcggaaaga atggcagata ttctacttgg tgaaggaaaa aaattatctc ctaaaaatta
     2281 tcgtttaaaa aagagtgagc atctattcga ttttactaga tatctagata gaaattttgg
     2341 attttttcat cattcatatg atgaaaaaat ctccgaatat gcgcctctcc atgcagtaga
     2401 gattaatgtt gatgctggtt acgagtcagg ctggggaagg acttttatga cagaggctgc
     2461 aacaaaatct gcttttttag agtcattaga gagatactgc aactctagaa atagacgcta
     2521 taaaaaatta attagagggt gtttttctga tttatctaaa aagtacaata cattaaatcc
     2581 tgttgatttt tgtctttcta ataaagaata tagagatagt tcctataaat ttcatgattt
     2641 tgattctgag aaaaattatg attggatatt tggtaaaaat ataactaccg gaaaaatttg
     2701 cttattgccc tcgcaactag tattttataa agactttagt aaaagcgaag aaaatgaaag
     2761 gtttgtttat gaaacatcaa atggatgtgc tttggggagt agtattgagg aagctatttt
     2821 ttatgggatt ttagagatta ttgaaagaga taatttttta cttacatggt atttaaaaga
     2881 agaagtaaaa caattatcat gggaatcttt accatctcgc ctacgtatta ttaatgaaag
     2941 actaaaagaa gataactgtg agctcaaact ttttaatata actaaagaag tgggcatacc
     3001 agtaatttgg gcattgtata taaatcataa tgaaaatgct agtattcgaa gtttttcagc
     3061 tgcaggctgt catattaatc ctttaagtgc aattgaatca gcaatttttg aagtaataac
     3121 ttctgtgcca acttttgaaa gattaattga agttagaaat aaagagtcat ttattgagga
     3181 aattcagaat aatttttctt taatacgaga tattgacgat catatattgt atcatgctca
     3241 tgcggattat aaaaataaaa tgcccttttt atttaaaaat aattatagtg aatatcaaaa
     3301 tgaatttgat gagaatagaa tttttaatac ttattcacat gcaacgctta catcagattt
     3361 acaggcacta ataaaaatta ttgaaaaaaa atttggagat atatatgtag tgaatataag
     3421 tgataaagtt tccgaaaaat ttggacttta ttgtgttaaa gtgttgattc ctggacttct
     3481 taatatgtca tttggacatt caaatcggcg tgtaaatata gagaggataa aaaattatgt
     3541 agattataga gggggaaatg taaatagtat tacattgaat tccataaacc atcttcccca
     3601 tccatttcca taagattata tataaaggaa taataaatga aaagagattg gaaatcaaag
     3661 catttatttt atcatgatgt tcaacaattt gataaattgg taatctattt atcaaaattt
     3721 atggataaat tagttaatca gaatcagatt gaaaaatatt tctatattcg ttattgggaa
     3781 ggggggcctc atattcgatt aagatatttg gtgagggata cacaaaattt tgaaacaatt
     3841 gatagtatga taaataagta tgcttataaa ttttgggaaa ataatcctcc aatgaagtta
     3901 ttaaataaga ccgattataa gaaaatttat aatgagagta ttgataacaa cggaaagatg
     3961 gatagaaaat tgaggaaaaa tgcgactatt gaaaacattg cctatatacc ggaaatagag
     4021 agatatggcg gggaagaagc tctgatagta agcgaagatc tattttgtat ctgtagtcag
     4081 gtttcaactg cgttacttaa tgtggtagat aactat
//
LOCUS       DAVBCA010000095         3964 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.095, whole genome shotgun sequence.
ACCESSION   DAVBCA010000095 DAVBCA010000000
VERSION     DAVBCA010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3964)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3964)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3964
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.095"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..370)
                     /locus_tag="VQU19_002017"
     CDS             complement(<1..370)
                     /locus_tag="VQU19_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000927991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2481205.1"
                     /translation="MLLVLVSLVHSFGSVSIIAHTIHQKFNLKVPNYRQEEDWARMGL
                     PITRKEISNWHIKASQYYLESLYKLLREKLLEQPLLHADETSYRVLESDSHLTYYWTF
                     LSGKAENQAITLYHHDQRRSG"
     gene            complement(446..1297)
                     /gene="rfbD"
                     /locus_tag="VQU19_002018"
                     /pseudo
     CDS             complement(446..1297)
                     /gene="rfbD"
                     /locus_tag="VQU19_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647909.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
     gene            complement(1363..2412)
                     /gene="rfbB"
                     /locus_tag="VQU19_002019"
     CDS             complement(1363..2412)
                     /gene="rfbB"
                     /locus_tag="VQU19_002019"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HET2481206.1"
                     /translation="MTEYKNIIVTGGAGFIGSNFVHYVYENFPDVHVTVLDKLTYAGN
                     RANIEEILGNRVELVVGDIADAELVDKLVAQADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGIYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQATD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKATIKWYTDNQEWWKAEKE
                     AVEANYAKTQEIITV"
     gene            complement(2422..3018)
                     /locus_tag="VQU19_002020"
     CDS             complement(2422..3018)
                     /locus_tag="VQU19_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HET2481207.1"
                     /translation="MTDNFFGKTLAARKVEAIPGMLEFDIPVHGDNRGWFKENFQKEK
                     VLPLGFPESFFAEGKLQNNVSFSRKNVLRGLHAEPWDKYISVADGGKVLGSWVDLREG
                     ETFGNTYQTVIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENLEEADVSEADKHHPLLKDVKPLKKEDLE"
     gene            complement(3019..3876)
                     /gene="rfbA"
                     /locus_tag="VQU19_002021"
     CDS             complement(3019..3876)
                     /gene="rfbA"
                     /locus_tag="VQU19_002021"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000676139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HET2481208.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLHRFQELLQDGSEFGIKLSYAEQPSTDGLAIGEEFISDDSVALIL
                     GDNIYHGPGLSTMLQKAAKKEKGATVFGYQVKDPERFGVVEFDTDMNAISIEEKPEYP
                     RSNYAVTGLYFYDNDVVEIAKSIKPSPRGELEITDVNKAYLDRGDLSVELMGRGFAWL
                     NTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRMGYISREDVLALAQPLKKNEYGQ
                     YLLRLIGEA"
BASE COUNT         1107 a          917 c          719 g         1221 t
ORIGIN      
        1 aaccactccg acgctgatca tggtggtaca gcgtgattgc ttgattctca gctttcccag
       61 acaaaaaagt ccaatagtag gtcagatggc tatcactctc tagaacccga taagaggttt
      121 catccgcatg aagaagaggt tgttctaaca acttttctcg taaaagctta taaagggact
      181 ctaaatagta ttgacttgcc ttgatatgcc aattagagat ttccttacgt gtgattggta
      241 aacccatcct agcccaatct tcttcttggc gataattggg taccttcaga ttaaacttct
      301 gatggatggt gtgagcgata atagaaactg agccaaagct atgcaccaaa gagaccagca
      361 ccaacaacaa gataattgta catcttaagc tcctttggag ttcattatct gcctctttta
      421 ttagactaga aaatcattct actacttatc tcacttcttg tttgtaaaat tcttgcaatg
      481 catcttgcca agttggaata acaaatccag tagctttggc tttggccagg ctcatcgttg
      541 agtttagcgg acgttgagct ttggctggaa attgactgga atctactggc ttgacttcga
      601 catctgtatc tttcaaaatt tcaactgcaa aatcatacca tgttgtgtct tctgtcgcat
      661 catttgacaa atgataataa ccaaattcct tacgattttc agctaggtag atcatgaatt
      721 cagccaaggt acgagtccaa gtcggacgac cgtactggtc atttacaact gttaaagtct
      781 tatgagtttt cgcaagattt tgcatggtaa aaacgaagtt tttgccataa tttccaaata
      841 cccaggcagt acggataata tagaaattag acacatgctt ctcaactaac tcttccccca
      901 tacgcttagt gcgtccatat tctgtctgtg gatctggtcg gtcatcaact tcccactctt
      961 gtccaactgg tttcttaccg tcaaagacct agtccgtaga aatataaact agagttgcac
     1021 catgcttttc agatgctttt gcgacatttt ttgtccccat cacattgatg gcgaagtcca
     1081 actcttttcc ttcatcctct gctgcatcaa cagcggtgta ggctgcacaa tggtagacta
     1141 aagtcggttt cacctcttca aaaactttct caaccatttc ttcattggta atgtccatct
     1201 cagccacatc tactgccacg tattcttcat tacgttcatc caataaatag cgaagttccg
     1261 ttcctaattg gccatttgcc cctgtaatta aaatcatctc tagacctttc taatatgtaa
     1321 ctcttcccaa tatagcaata aaaagcagcg atttcctgct ttttatactg taataatctc
     1381 ctgagtctta gcataattgg cttcaacagc ttctttttct gctttccacc attcttggtt
     1441 atctgtatac cacttgattg ttgccttgag cccagcttca aagttggtaa attcaggttt
     1501 ccaccccaac tcatcacgga gcttgctggc atcaatcgca tagcgaaggt catgtcctgc
     1561 acggtcagtc acatgatcat aggcatccgt agcttgtccc atttccttaa ggataagttc
     1621 caaaacttcc ttattgttct tctcaccatc agccccaatc aagtaggttt caccgatttg
     1681 cccttttgtc aagattgtcc aaactcctga agaatggtca ttggtatgaa tccagtcacg
     1741 aacgttctta ccttcaccgt aaagttttgg cttaattcca cttaggatgt tagtaatctg
     1801 acgtgggatg aatttttcga tatgttgata aggaccgtag ttatttgaac agttggaaat
     1861 cgttgccttg actccaaaag aacgcaccca ggctttgaca atcaagtctg atgcggcctt
     1921 ggttgatgag tacggagagc ttgggttgta ttttgtttca gcagtaaatt tctcacctgg
     1981 tccttcacca tgacctggca aatcttctcg taaagggaga tccccataaa cttcatctgt
     2041 cgatacatgg tggaagcgaa tatcatactt acgagcagct tctaaaagag tatagattcc
     2101 aatgaagtta gtatgaataa atggcgatgg atcattgagc gaattatcat tgtggctttc
     2161 cgctgcataa tgaacgatag catctgcttg agcaaccaac ttgtctacca actccgcatc
     2221 agcaatgtca ccaacaacta actcaacacg attgcctaaa atttcctcaa tattcgcgcg
     2281 gtttccagca taagtcaact tatctaggac tgtcacgtga acatctggaa agttctcgta
     2341 aacataatgg acaaagttag aaccgataaa gccagctcca cctgtcacga taatattttt
     2401 gtattcagtc atattctttc cttattccaa atcttctttt ttcaaaggct tcacgtcctt
     2461 aagtagggga tgatgtttgt ctgcttcaga tacgtctgct tcttccagat tttcccattc
     2521 aataccaagg cttggatcag cgtagttcac aaaggcatac ttgggtttga gttcaagagc
     2581 ccagtaatca ttgaccagat agctatatga cactgtatct gataaaactt ggaagccatt
     2641 agctacgcct cgaggaacaa agattccctt gcttgcatca attactgtct gataggtatt
     2701 cccaaaggtt tcaccctcgc gtagatcaac ccaagaaccc agaactttcc ctccatctgc
     2761 tacagagatg tacttatccc aaggctctgc gtggaggcct cgaaggacat ttttacgtga
     2821 gaaggataca ttgttttgca attttccttc tgcaaagaaa gactctggaa atccaagtgg
     2881 aagcactttt tccttttgga aattttcttt aaaccagcca cgattatctc catgaacggg
     2941 gatatcaaac tccaacatgc ctggaatagc ttcaaccttg cgtgccgcaa gcgtcttacc
     3001 gaaaaaatta tctgtcatct atgcttctcc aatcaaacgg agcagatact gtccgtattc
     3061 atttttctta agtggttggg ctaaggccaa tacatcttct cgactgatat agcccatacg
     3121 gtaagcaatt tcttctaagt ttgctacctg aacattttgc atccgttgca ctgtttcgat
     3181 gtactgtgaa gcctctagta aactttcatg agttccagta ttcagccaag caaagccacg
     3241 tcccataagc tcaacagaca aatcaccacg atctaggtaa gccttgttta catctgtaat
     3301 ttccagttca ccacgagggc ttggtttaat actcttggca atttcgacaa catcgttatc
     3361 atagaaatac agtcctgtca ctgcatagtt ggagcgagga tactccggtt tttcttctat
     3421 ggaaatagca ttcatgtctg tatcaaactc aaccacacca aaacgctctg gatccttcac
     3481 ttggtagcca aaaacagtcg cacctttctc tttcttggct gctttttgaa gcattgtgct
     3541 cagaccagga ccatggtaga tattgtcgcc taaaatcaag gcaacgctat cgtcagaaat
     3601 aaactcttcc ccaattgcca aaccatctgt acttggttgc tctgcataag aaagtttgat
     3661 cccaaactca gatccgtctt gaagaagctc ttgaaatcga tgtaaatcct gtggagtgga
     3721 aataatcaaa atatccctaa tcccagccaa catcaatgtt gaaagtgggt agtaaatcat
     3781 cggtttatca taaaccggca taagttgttt tgacgcagcg cgagtcaaag gatataaacg
     3841 tgtccccgaa ccacctgcta gaataatacc tttcatagta gggtaccttt ctttgttatt
     3901 ttagagtcaa ttactattaa ttgtgtactg ctctaaaaag aaaacaatca tcccatgttt
     3961 tata
//
LOCUS       DAVBCA010000096         3939 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.096, whole genome shotgun sequence.
ACCESSION   DAVBCA010000096 DAVBCA010000000
VERSION     DAVBCA010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3939)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3939)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3939
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.096"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            98..1357
                     /locus_tag="VQU19_002022"
     CDS             98..1357
                     /locus_tag="VQU19_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HET2481209.1"
                     /translation="MKVFQHVNIVTCDQDFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQIQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    1433..1568
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            1607..2107
                     /locus_tag="VQU19_002023"
     CDS             1607..2107
                     /locus_tag="VQU19_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HET2481210.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            2183..2551
                     /gene="rplL"
                     /locus_tag="VQU19_002024"
     CDS             2183..2551
                     /gene="rplL"
                     /locus_tag="VQU19_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HET2481211.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKTKLEEAGASVTLK"
     gene            2738..2908
                     /locus_tag="VQU19_002025"
     CDS             2738..2908
                     /locus_tag="VQU19_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2481212.1"
                     /translation="MQKEGQSSRQFVKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVGILVLEGQ"
     gene            2908..3156
                     /locus_tag="VQU19_002026"
                     /pseudo
     CDS             2908..3156
                     /locus_tag="VQU19_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            3170..3510
                     /locus_tag="VQU19_002027"
                     /pseudo
     CDS             3170..3510
                     /locus_tag="VQU19_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812122.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3503..3883
                     /locus_tag="VQU19_002028"
     CDS             3503..3883
                     /locus_tag="VQU19_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HET2481213.1"
                     /translation="MIDLYLSKNRQRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFVEIILKNPELTIRLPLAVSNKRVYPSLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
BASE COUNT         1260 a          700 c          842 g         1137 t
ORIGIN      
        1 agatagaact gacgaagtca gtaaccacac ctacggcaaa gtgaatctga agtggtttga
       61 agagagtaca acttgtcttt tagaaaagga gcctataatg aaagtctttc agcatgtaaa
      121 tatcgtgact tgtgatcaag atttccatgt ttatcttgat ggaatcttag cagtcaagga
      181 ttctcaaatc gtctatgtcg gtcaagataa gccagcgttt ttagagcaag ctgagcagat
      241 tatagactat cagggagctt ggattatgcc tggtttggtc aattgtcaca cccattctgc
      301 aatgacaggt ctgagaggga tccgagatga cagcaatctc catgaatggc tcaatgacta
      361 tatctggcca gcagaatctg agtttactcc cgacatgact accaatgcgg tcaaagaagc
      421 cctgacagag atgctccagt caggaacaac aacctttaac gatatgtata atcccaatgg
      481 tgtggatatc cagcaaattt atcaggtggt gaaaacttcc aagatgcgtt gttatttttc
      541 tccgactctc ttttcttcag agacagaaac aactgctgag actataagca gaactcgatc
      601 catcatagac gaaatcttaa aatataaaaa tccaaatttc aaggttatgg tagcacctca
      661 ttctccgtat agctgcagta gagacttgct ggaagcgagt ttggaaatgg caaaagagct
      721 aaatattccg ctccatgtcc atgtggcgga gaccaaggag gagtcaggaa ttatcctcaa
      781 acgatacggc aaacgccccc ttgcttttct tgaagaactg ggttatttag atcatccgtc
      841 cgtatttgct cacggggtcg aattaaacga gagagaaatt gaacgcttgg catcttctca
      901 agtggctatc gcccacaatc ctatcagtaa cctcaaactg gcatcaggaa ttgctccaat
      961 tatccagatc caaaaagcgg gagtagcagt cggaattgcg actgactcgg ttgcttccaa
     1021 taacaatcta gatatgtttg aggaaggaag gactgcagct cttcttcaga agatgaaaag
     1081 tggggatgcc agccagtttc caatcgaaac agctctcaag gtactgacaa tcgaaggggc
     1141 taaggtcctt ggaatggaaa atcagatagg aagtctggaa gtcggcaagc aagcagattt
     1201 tctggtcatt caaccacaag ggaaaattca tctccaacct caggaaaata tgctgtctca
     1261 cctggtttat gcagttaaat ctagtgatgt agatgatgtt tatatcgccg gagaacaggt
     1321 tgttaagcaa ggtcaagtcc tgacagtaga actttaaaag aaaaatcacg aaaaatttta
     1381 aaaaaagttt gcaaaaatct tgcattcttt ttttgactat gctatactta tatacggttt
     1441 aaaaaaactg cctaagacag taggggagct cgactcataa atatcctacc gaggacaaga
     1501 cgtatcatgt aaaaagaagc gtattgtact ttcgtgtcta ggtttgggcg cgtttttctt
     1561 tttgaaaaat tccccaagca aaataattac ggaggtgaac acactaatga gtgaagcaat
     1621 tattgctaaa aaagcggaac tagttgacgt agtagctgaa aaaatgaaag ctgctgcatc
     1681 tatcgtcgtt gtagacgctc gtggtttgac agttgagcaa gatacagttc ttcgtcgcga
     1741 gcttcgtgga agcgaagttg agtataaagt tattaaaaac tcaatcttgc gtcgtgcagc
     1801 tgaaaaagct ggtcttgaag atcttgcatc tgtatttgtt ggaccatctg cagtagcatt
     1861 ttctaatgaa gatgttatcg caccagcgaa aatcttgaac gacttttcta aaaacgctga
     1921 agcacttgaa attaaaggtg gtgcaatcga aggcgctgtc gcatctaaag aagagattct
     1981 tgcacttgca actcttccaa accgcgaagg acttctttct atgctccttt ctgtacttca
     2041 agcgccagtg cgcaacgttg ctcttgcagt caaagcggtt gcagaaagca aagaagacgc
     2101 ggcttaatct taagctacac agcgtagcct agctacgaaa aaaactatta taaaatttaa
     2161 aacttatttg gaggaaataa caatggcatt gaacattgaa aacattattg ctgaaattaa
     2221 agaagcttca atccttgaat tgaacgacct tgtaaaagct atcgaagaag aatttggtgt
     2281 aactgcagct gctcctgtag ctgttgctgc agctgatgca gctgatgctg gtgctgctaa
     2341 agattcattc gacgttgaat tgacatctgc aggcgacaaa aaagttggcg ttatcaaagt
     2401 tgtacgtgaa atcactggtc ttggtcttaa agaagctaaa gaacttgttg acggtgcacc
     2461 agcacttgtt aaagaaggcg ttgcaactgc agaagctgaa gaaatcaaaa ctaaattgga
     2521 agaagctgga gcttcagtta ctcttaaata atagagtatc gcaatttgat tgcggaatcc
     2581 ctatttacca gtctttgaga gcgataagcg attgatagaa actgataaat tgatttggtt
     2641 tcctgccaaa aattctttgg caggattttt gttttaataa actttcgggg gtagacacta
     2701 gattgtctac cccttttttt gtgtttcgga ggtaattatg caaaaggaag gacagtcatc
     2761 acgtcaattc gtgaagagtc atctcatgac tatcatggga gttgatattg taaaagcaac
     2821 tcagttagtt gatgaaatgg aacaagtagg tttaatccga tttgatgaat ttggaaatgt
     2881 tggaatttta gtcttggagg gacaataatg aagtgtatta ccgctaatca atatcagaca
     2941 tcagagcgtt attataagct ccccaaactt ttatttgaga gtgaacggta taagaatatg
     3001 aaactggagg ttaaggtggt ttactcagtt ttaaaagatc ggttggagtt gtctttgagc
     3061 aaaggttgga ttgatgagga tggggctatt tatttgattt attccaattc aaatttgatg
     3121 gcacttttag gctgttcaaa gtcaaaatta ctctccatgt gagtttgaag tgacattttt
     3181 agatgattac cataaaaaac ataactaccc actattttac gaatcctatc ttcaaaacgt
     3241 tatggaattc cttgaaagtc aagacataaa gaatggggtt gatgcctttg tagatgatca
     3301 tcaaaatctc gtttttgttt tatatggaca aggctatcga gccgagggaa aagagggaat
     3361 acttacaacc caagtaactg taaaagctta tgatgaagac aagaaaccga ttaacttcgc
     3421 aaatttatta gattccttaa tttattagat tccttaatcg tgtcagaata tcaaatggaa
     3481 ccgaatcttt gggaggtctc ccatgattga tctctatcta agtaaaaata gacaaagaaa
     3541 tcaacttctt ttagatttct tccaaaacta tggcatagag gtatcttgtc attcagtttc
     3601 tgaaatgaca aaggacaaat taattgagat gatgagctat tcttcagatt gttttgagtt
     3661 tttatctccc aatttattac gatttaagaa ccgtgacaat ctaagattaa cggatttcgt
     3721 tgagataatt ttaaaaaatc ctgaactaac catcagactt cctcttgcgg tttcaaataa
     3781 gcgagtttat ccaagtctga atttggaaga ggctagagct ctattgccaa gagatacgaa
     3841 acaattgatt tacatggcgc aaacacatta tttatctaac taaaggagaa gcaatatggc
     3901 tgaacgattt tgggagaact tgtccattat tttggctga
//
LOCUS       DAVBCA010000097         3418 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.097, whole genome shotgun sequence.
ACCESSION   DAVBCA010000097 DAVBCA010000000
VERSION     DAVBCA010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3418)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3418)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3418
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.097"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            1..497
                     /locus_tag="VQU19_002029"
                     /pseudo
     CDS             1..497
                     /locus_tag="VQU19_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000547411.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(577..777)
                     /locus_tag="VQU19_002030"
     CDS             complement(577..777)
                     /locus_tag="VQU19_002030"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2481214.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDKTDEVSSKHGFEVVDETDEVS
                     NHTYGKATLTRIEEIFEEYKSS"
     gene            complement(755..949)
                     /locus_tag="VQU19_002031"
     CDS             complement(755..949)
                     /locus_tag="VQU19_002031"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2481215.1"
                     /translation="MSSKKHPLGEKRNHTGSKLRQGFWMVFRLGVNNWGFKEIENKKP
                     SKNSIAGENEIILNENQRAN"
     gene            1011..2357
                     /locus_tag="VQU19_002032"
                     /pseudo
     CDS             1011..2357
                     /locus_tag="VQU19_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISSpn5 family transposase"
     gene            complement(2757..>3418)
                     /locus_tag="VQU19_002033"
     CDS             complement(2757..>3418)
                     /locus_tag="VQU19_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2481216.1"
                     /translation="IIRKVQEPEFWKEVNLSDLEKIRLAIRDLLQFLDKTDRKPYYVN
                     FEDRILSTVHETTAFLQVNDLRSYNEKVEHYLKTHLDEESISKLYHNKKLTSDDMLAL
                     EKLLWEKLGSKADYQSHYENKAIPRLVREIIGLDRESANRIFSKFLSDENLNARQISF
                     VKLIVDYIVENGFLETKVLTQEPFKSYGSVQLLFQHQLPVLRNIVQIIELINNRAGEA
                     A"
BASE COUNT         1049 a          702 c          621 g         1046 t
ORIGIN      
        1 tcagccaaaa taatggacaa gttctcccaa aatcgttcag ccatattgct tctcctttag
       61 ttagatgaaa aggaggtaaa ccatctgatt aaatatgcca tgtttgataa ggaacagaag
      121 agaggctata aacagtcagc tagaaactta gcgaattggt actataatga caaggaggat
      181 agctatacac atcctgatgg ctggtattat cgttttcacc ataccaaaca tcagaaaaca
      241 cagacagact ttaaacaaga aatcaaggtt tactacgccg acgaacctga atcagcccct
      301 caaaagggac tgtatatgaa cgaaggctat caaaacttga aagctaaaga atgtcacctg
      361 tctttgggca gataaaggct tgtttgggtt acaagagatg taatctgagg ggcaagcgtc
      421 aagtgagaat tgacatggga ttggtactta tggccaataa cctcctaaaa tacaataaga
      481 gaacgactca aaattaaaaa gctaaagttc cacaattgga aatctctagc ttttttgtgg
      541 tcgagaacta ttttgtccca ggctctttgc tttatcctag gaagatttat actcttcgaa
      601 aatctcttca atccgcgtca acgtcgcctt gccgtaggta tggttactga cttcgtcagt
      661 ttcatctaca acctcaaaac catgttttga gctgacttcg tcagtcttat ctacaacctc
      721 aaaacagtgt tttgagcagc ctgcagctag tttcctagtt tgctctttga ttttcattga
      781 gtattatttc attttctcct gcaattgaat tcttgctcgg ctttttgttt tctatttctt
      841 taaaacccca attattcacc cctaatctaa aaaccatcca gaatccttgc cttagcttag
      901 atcctgtatg gtttcttttt tcacccaatg ggtgtttttt actagacaaa aaagaatttc
      961 ccctttatgg tataagtgta gaaaaaaaca caaaaagaaa ggaaactcac atgaacagtt
     1021 taccaaatca tcacttccaa aacaagtctt tttaccaact atctttcgat ggaggtcatt
     1081 taacccagta tggtggtctt atcttttttc aggaactttt ttcccagttg aaactaaaag
     1141 agcggatttc taagtattta gtaacgaatg accaacgccg ctactgtcgt tattcggatt
     1201 cagatatcct tgtccagttc ctctttcaac tgttaacagg ctatggaacg gactatgctt
     1261 gtaaagaatt gtcagctgat gcctactttc caaaattgtt ggaaggaggg cagcttgctt
     1321 cacagccaac cttatcccgt tttctttcca gaactgacga ggaaacagtc catagtttgc
     1381 gatgcctcaa ccttgaattg gtcgaattct ttttacagtt tcaccagcta aaccaactca
     1441 ttgtagatat cgattctacc catttcacaa cttatggcaa gcaagaaggt gttgcttata
     1501 acgcccacta tcgtgctcat ggctatcatc ctctttatgc tttcgagggg aagacaggtt
     1561 attgtttcaa tgcccagctt cgtcctggta atcgttattg ttctgaagag gcagacagct
     1621 ttatcacacc tgttttagaa cggtttaatc aacttctctt tcgaatggat agtggctttg
     1681 cgacccccaa attatacgat ttaattgaaa aaacagggca atactaactc ataaaactca
     1741 agaaaaatac tgttctgagc cgtcttggag acctttccct cccttgccca caggatgagg
     1801 acttaaccat cttgccccac tccgcctact cagaaactct ctatcaagca ggatcttggt
     1861 cgcacaagcg tcgtgtctgc cagttctctg aacgaaaaga aggaaacttg ttctacgatg
     1921 ttatttctct cgttacaaat atgacgagtg gaacaagcca agaccagttt cagctttatc
     1981 gtggacgtgg tcaagccgag aatttcatca aggagatgaa ggagggattt tttggcgata
     2041 aaacggatag ttcaacctta atcaaaaacg aagttcgtat gatgatgagc tgtatcgcct
     2101 acaatctcta tctttttctc aaacatctag ctggaggtga cttccaaact ttaacaatca
     2161 aacgcttccg ccatcttttt cttcacgtgg taggaaaatg tgttcgaaca ggacgcaagc
     2221 agctcctcaa attgtctagt ctctatgcct attccgaatt gttttcagca ctttattcta
     2281 ggattagaaa agtcaacctg aatcttcctg ttccttatga accacctgga agaaaagcgt
     2341 cgttaatgat gcattaaaga acagtcgaga tgaaaaaatc gtgtgacgca ccaagggagg
     2401 agtctgccct tttgaggaaa tctagcgagg aaaaacgata ctggaacagc agaaagtaaa
     2461 actgacctca tgaggaggaa gaaagtggct catgaggtca ggggttttgt aagttacatc
     2521 tagttgagag aggtatgaat gatttgggtt aaaatcaaag tagctctttt gttaataact
     2581 cgatcaacaa acatcgtggt acaagtatct actttgaaat ttatcaacca cttaacaact
     2641 gatactgtat tctaggaaaa cgatgacatt cttcctaata aaacttctca tatatagcat
     2701 aaatttctac tctttttaat tttaaatgag tctcagcatg gcaatcactt tagaatttaa
     2761 gccgcttctc cagctcgatt attgataagt tcaatgattt gaacaatatt acgaagtact
     2821 ggtagttggt gttggaagag tagttgaaca gaaccataag atttaaacgg ctcttgcgtt
     2881 aacactttcg tctctaaaaa accattttct acaatgtagt ctacaatcaa ttttacaaat
     2941 gaaatctgcc tggcattaag attctcatcc gacaaaaatt tagagaaaat acgattggca
     3001 gactctctat ctaagccaat aatctcacga accaatctcg gaattgcctt attttcataa
     3061 tgactttggt agtctgcttt actacctaat ttttcccaaa gcaatttttc aagtgcaagc
     3121 atatcatcag atgtcaactt tttattatgg tatagcttag aaatggactc ctcatccaga
     3181 tgagttttca aataatgctc aactttttca ttgtaagacc gaagatcgtt gacctgcaaa
     3241 aatgctgtgg tctcgtgaac agtggagagt atacgatctt caaagttaac atagtagggt
     3301 ttacggtctg ttttatccaa aaactgtaat aaatctcgaa tagcaagacg aattttttcc
     3361 aaatcagaca agttaacttc tttccaaaat tcaggctcct gtactttcct gataattt
//
LOCUS       DAVBCA010000098         3408 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.098, whole genome shotgun sequence.
ACCESSION   DAVBCA010000098 DAVBCA010000000
VERSION     DAVBCA010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3408)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3408)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3408
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.098"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            2..1242
                     /locus_tag="VQU19_002034"
     CDS             join(2..341,341..1242)
                     /locus_tag="VQU19_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HET2481217.1"
                     /translation="MVKLIDRYGIEIVKKGKNRHYSSKLKQEMMDKALLEGCSQRSIS
                     LDYALPNQGMLSFWPAQYKKNGYTIVEKTRGRPAKMGRKRKKTWEEMTELERLQEENE
                     RLRTEVAYLKKFKRVRGKGRSPRARKAETVREMVSGGFRLDFLLETARLARSTYYYQL
                     KQLDGVDKDKEIKTEIQGIDNEHKGNYGYRRIHLELRNRGFVVNHKKVQRLMRILGLT
                     ARIRRKRKYSSYQGEIGKKAENLIQRQFEASRPMEKCYTDVTEFAIPNSTQKLYLSPV
                     LDGFNSEIIAYHLSTSPNLEQVKSMLEQAFTEKYYENTILHSDQGWQYQHDSYHRFLE
                     SKGIQASMSRKGNSPDNGMMESFFGILKSEMFYGYEKNFRSLENLEQAIVDYIDYYNN
                     KRIKVKLKGLSSVQYRTKSFG"
     gene            complement(1477..2085)
                     /locus_tag="VQU19_002035"
     CDS             complement(1477..2085)
                     /locus_tag="VQU19_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001165927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HET2481218.1"
                     /translation="MQIKFIDKVSNLIMLNLLYVASVVTVIAIGSGESALIATLIKIV
                     RHEESYPYRDFANSFFKDYWKNLGAALISNLPILILLFSLFFLPYIPLPIYIISILRH
                     IGVIYIILHLIATTFLIPLIGRYNNTLKNSLHNSIMLAYKHFFIAVLIRIIEIIPVLL
                     FFILQNQLLVWITLMIFILPSITKYANAFLYNFIFSKYEKLN"
     gene            2251..2421
                     /locus_tag="VQU19_002036"
                     /pseudo
     CDS             2251..2421
                     /locus_tag="VQU19_002036"
                     /inference="COORDINATES: protein motif:HMM:NF013577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
     gene            2410..3021
                     /locus_tag="VQU19_002037"
     CDS             2410..3021
                     /locus_tag="VQU19_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001821036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HET2481219.1"
                     /translation="MTKDILELESQKMSSDTFIDEIKNNYLSIVESTRKLIDGRQIEL
                     AIKLIREANQILMIGVGSSGNAAREFESSLLRIGIISKTVIDTHFQLMHTALLKDNDL
                     IIAFSLSGSTKEVEETLLNAKRKNVKIISITNYSSRNIAKLSDCVLLTSKKESYLEGG
                     SLMAKASQLFIIDVICTRLSLINYEDTICKKEEIASLLSNKVE"
BASE COUNT         1290 a          433 c          604 g         1081 t
ORIGIN      
        1 catggtgaaa ttaattgacc gttatggcat agaaatcgtt aaaaaaggga agaatcgtca
       61 ctattcttct aaattgaaac aagaaatgat ggataaagcc ttactggaag gttgttcaca
      121 aagaagtatt agtcttgatt atgccctccc aaaccaagga atgctttcat tttggccggc
      181 acaatacaag aaaaacgggt atactattgt tgagaaaaca agagggagac cagctaaaat
      241 gggacgtaaa cggaagaaga cttgggaaga aatgacagaa ctagaacgac tccaggagga
      301 gaatgaacgc ttacggactg aggtggccta cctaaaaaag ttaaaagagt tagaggaaag
      361 ggacgaagcc ctagagcgag aaaggcagag acagttagag aaatggtttc aggaggattt
      421 cgactagatt ttcttcttga aacagcacgt ttagctcgct cgacttacta ttatcagttg
      481 aaacaactgg atggggttga taaagataaa gagattaaaa ccgaaattca gggcattgat
      541 aatgaacata aaggcaacta tggctatcgt cgaatccatt tagaactaag gaatcgtggt
      601 tttgtggtca atcataagaa agttcaacgg ttgatgagaa ttcttggttt aacggctcga
      661 attcgccgta aacggaagta ttcttcctac caaggagaga ttggcaagaa agcagagaat
      721 ctcattcaac gccagttcga agcatcgagg ccaatggaaa agtgctatac agatgtgaca
      781 gagtttgcca ttccaaatag cacacagaaa ctctatttat caccagtttt agatggtttt
      841 aacagtgaaa tcattgctta tcatctttct acttcgccaa acttagaaca agtgaagagt
      901 atgttagaac aggcctttac agagaaatac tatgagaata cgattctcca tagtgaccaa
      961 ggctggcaat accaacacga ttcttatcat cggttcctag agagtaaggg aattcaagca
     1021 tccatgtcac gcaagggcaa cagcccagac aacggcatga tggaatcttt ctttggcatt
     1081 ttaaaatccg aaatgtttta tggctatgag aagaacttta gatctttaga aaaccttgaa
     1141 caagctattg tggactacat tgattactac aacaacaaac gaattaaggt aaaactaaaa
     1201 ggacttagtt ctgtgcagta cagaactaaa tcctttggat aaattatttg tctaattttt
     1261 tggggtcagt acagtattaa ataccatgat cttatgcgtt ttataataaa aaatctgttc
     1321 ttgttttatt tttagaaaat ttactaaaga ctaaaaatat tatgaataat ttaaaaaata
     1381 gtcaggttat atagtttttt gaaattaaaa ttattttatc gttgaaatta gttaaaaatt
     1441 tttataaaat caagatgcaa ggctatgaga tgttctctag tttaattttt catacttcga
     1501 gaatataaag ttatataaaa atgcattagc atattttgtt attgagggaa gtataaaaat
     1561 cattaaagtt atccaaacta gtaattgatt ctgtaatata aagaagagta gaactgggat
     1621 aatttcaata attctaataa gaacggcaat aaaaaaatgt ttataggcta acatgattga
     1681 attgtgtaga gaatttttta aagtgttatt atatctaccg attaaaggaa ttagaaatgt
     1741 tgttgctatt aaatgaagta tgatatatat tactccaata tgtcgtaaga tagaaatgat
     1801 atatataggt aatggtatgt agggtaggaa gaacaaactg aataataaga ttaaaattgg
     1861 taaattagat attaatgctg ctcctaaatt tttccaataa tctttaaaaa aactgtttgc
     1921 gaagtctcta tagggatagg attcctcgtg tcgtacaatt tttattagag ttgctattag
     1981 ggcactttca cctgatccga tagcaataac tgttactact gacgctacat agagtagatt
     2041 taacattata agatttgaaa ctttatcaat aaattttatc tgcatcttta actcctgctg
     2101 tttttatact tataatatca catcatttga gtttcatcaa ctttgaatac attaagaaag
     2161 aatataacta tgaggaaagg aaaaaattat tatgaataaa tccaaaaaat ataaagaaag
     2221 aattcattat gaatacgata atcttactaa atcagagaaa aaattgctga ctatatttta
     2281 gttagagata gtgaaatagt ttatgaaacg tcttcagaaa ttgttagtaa agtaaaagtt
     2341 ggagagggaa ctcttaatcg attttgcaaa aagattggat actctggttt tcaggaacta
     2401 aaattaaaaa tgacgaaaga tatattagag ttagaatctc aaaaaatgag tagtgacaca
     2461 tttattgatg aaataaaaaa taattattta tctattgtgg aaagtacaag aaaattaatt
     2521 gatggtagac aaatagaatt agctataaaa ttaataagag aagcaaacca gattttaatg
     2581 attggtgtgg gttctagtgg aaatgcggct agagaatttg agagtagttt gttaagaatt
     2641 ggaataataa gtaagacggt aattgatacc cattttcaac tcatgcatac tgcgttattg
     2701 aaagataatg atttgataat agcgtttagt ttatctggtt ccacaaaaga agttgaggaa
     2761 actttattaa acgcaaaaag aaaaaatgtt aaaattattt caataacaaa ttattcgtcc
     2821 agaaatatag caaaattatc tgactgcgtt cttttgacat caaaaaaaga atcttattta
     2881 gagggtggta gtttaatggc taaggcttct caactattca taattgatgt aatatgcact
     2941 agactctctt taataaatta tgaagatact atatgtaaaa aagaagagat tgcttctttg
     3001 ctgtcaaata aagtggaata aatcaataat ttttaaattt taataaaaat tttttaaaat
     3061 aaattaaaaa acgatcctaa aagggtcgtt tttttgctaa agttttaaaa ataaacaata
     3121 attaagatta tagtgcgttg aatctatatt aggacataac aattcttaaa tcattgttag
     3181 aaattagttt gaattttcca atcaatttgt tcgattttta catcattgca ttatatcacg
     3241 tgactattaa ccttgttttc tcctaaaatt gattttcttc ttttcttatc ttgtccactc
     3301 gaaacaagta ttgtaagaat ttgattattt ttgaaagtac ttttaatata tttgagatag
     3361 ttaaaaaaga tttgaaacta aattccaaat tagaaaaaga cttgaaat
//
LOCUS       DAVBCA010000099         3309 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.099, whole genome shotgun sequence.
ACCESSION   DAVBCA010000099 DAVBCA010000000
VERSION     DAVBCA010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3309)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3309)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3309
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.099"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            260..849
                     /locus_tag="VQU19_002038"
                     /pseudo
     CDS             260..849
                     /locus_tag="VQU19_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809094.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(815..2290)
                     /locus_tag="VQU19_002039"
     CDS             complement(815..2290)
                     /locus_tag="VQU19_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HET2481220.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEEVIELSEYARHEINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDDSVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
     gene            2997..>3309
                     /locus_tag="VQU19_002040"
     CDS             2997..>3309
                     /locus_tag="VQU19_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HET2481221.1"
                     /translation="MQDNYTTKGKHLTIDSRRLIERWKKEGKSNREIASLLGKAPQTI
                     HTKIKRRTVRKCLGKGRFKEVYSADYAQQSYENNRKHSVKRSSVTKELKEKILHYHNQ
                     KF"
BASE COUNT         1040 a          715 c          590 g          964 t
ORIGIN      
        1 tctaaccaca gctttttgtt tcaattggta atgagtttga taacgcatag acgttttatc
       61 tcgtctaagg taacaaggca aaaagttcgt ggataaccaa gtagacttga aatactatat
      121 ctggaggtac tcccatgctt tatgtgggca ttgatgtcgc taaaaataaa cacgatgtta
      181 cagccttgaa tgttcgagga aaactgttct taaaccactc actttttcaa ataataaagc
      241 tggttttgaa ctcttagatc tgtctcttcg acaactcaac caagactgtc tcatcgctct
      301 tgaaaatacc ggacattatg cctttaatct actgaacttc ctgcatgaac aaggatataa
      361 agtttacacc tacactcctt tgctcatcaa ggaatttgcc aaatcattat cacttcgcaa
      421 gactaaaacg gataagaaag acgctcatgg catcgctctt aaacttcttt ctgaccccaa
      481 tcgtgaacaa tttcaacacg ataatcggca agtagaacta aaaatactga ctagacatat
      541 tcatcgtctc aagaaaaaac agtctgattg gaaagtacaa tacactcgtt gtcttgatat
      601 catctttcct gagttggata aaatcgttgg aaagcattca gaatatacct accaactctt
      661 gacacgctac cctaatcctc agaaaaggat tgaggcagga tttgataagc tgatagaaat
      721 taagcgattg accgcttcta attcaagggc tttttgccgt gctctaaaat catcgccaaa
      781 tcatcaaatt gaaataagaa atagtttaga taaactattg acttttctta tagtttgtct
      841 ttctcttaat aacgttgata tgattgacct ctggatcttc cgtcccttgg agggagcaac
      901 cacgttcctt ggcgaattgg atatagtcga caatttctcg tgtaatgcgt tcaccaggag
      961 ccaagatagg aatacctgga gggtaacaca taacaaattc tccacagacc tgtccaacag
     1021 aatcatccaa agttaaactt tttctttctg aatagaaggc ttcttgcgga gacagcacta
     1081 actcgggctg aatatattct cctgctatca aatcttttcc atctcttgaa tagagtctct
     1141 taatatcagc cagagcacca accaagcgct cgatgtcttg gatgcggtcg ccgatggaaa
     1201 tataggccaa gatattgccg atatcaccaa actcgatctg aatgtcgtat tcgtctcgca
     1261 agaggtcata aacctcgata cctgttaagc caataccctg agtgtaaact gacaacttag
     1321 ttacgtcaaa atcgcaaacc gaaacaccgt ctattaactc ttttgagtag gcatagtagc
     1381 caccgatagc attgatttca tgacgagcgt actcggatag ctcaatgact tcctcaaacg
     1441 actctttacc acgaagggcc aagttgcgac gtgaaatatc caaactagcc atcaataagt
     1501 aagaggcaga tgtagactgg gtcaggttta taatctgacg aacgtactcg ggattcatct
     1561 gctccccgat taaaagaagc gaactttgtg tcaaactccc accagactta tgcatggaaa
     1621 ctgctgccat atcagctcct gcatccatag cagaaattgg aagtttacca gtgaaatgca
     1681 aatgcgctcc atgggcttca tctactaaaa ccatcatgcc agcttcatga gccatttctg
     1741 tcaacccctt taggtctgaa cagatgccgt agtaagtagg attgttgatt aggatagcct
     1801 tagcatctgg atggtccttt atggcctgtg ctactcggtc attttcaaga cctaaagcga
     1861 taccaatctt aggatctaca ctcatctcga tatagatggg aatggcacca catagaacca
     1921 acgcattgat agcagattta tggacatttc gtggcagaat aatcttatct cctgccttgc
     1981 aggttgccag aatcatagtc tgcaccgatg aagttgttcc accaatcatt agaaaggcat
     2041 ggctagctcc aaaagcatct gcagccagct cctctgcatc acgaataatc gaaataggat
     2101 ggcctaaatt atccaagggt ttcatcgaat tgacatcaat gcctacacat ttttctccta
     2161 agagttcgac aagttctgga tttccccgtc cacgcttgtg acctggaaca tcaaagggaa
     2221 caatcctttt cttgcgtaac ttcaccaagg cctcataaat tggggcttgg ttttgatcta
     2281 actctttcaa aacatactcc tttcaatatt tttaggacct tatgaaaact aaggaactaa
     2341 aggttgactc atgaaaaaag agcaggtttt cacctgctct gcaatcttct gacgtgttta
     2401 ttttggtttc tgttgagtat gtctgttccc gatgtttcct aactctctag tagcaaatat
     2461 tacgtacttt attgatcgtt tcacaagatg acgtgtgctt tcaccacact aaaaatttat
     2521 gaattaggac aagtgtccta acatcaactt ataaaagtag gcttttaacc ctatcaataa
     2581 tgtggctttt caaccacgct tcggcattca accctgcctg tccgtaggca ttttttactc
     2641 gggtttatat ttgctagaaa acatcatctc attttctaag ctttattact atatcatgtt
     2701 tttaagaact tgtaaagtat tttttgataa aaaacaaaaa tataatagat tgaaactaga
     2761 atagtacacc tctgcttcta aaacattgtt agaaatagat tttactgtcc tgatcgattt
     2821 gttctgttct tgtttcattt tactatatgt tcgtaaatga aagttctata atgaagttag
     2881 ccacccagcc ctcctaaaaa ttagatggtt caactagctg atagctcttg taggcataag
     2941 aaaacacctc tgtgttatac ttgttgttca accacaaaca caagaaaggc acagaaatgc
     3001 aagacaatta tactacaaaa ggtaaacatt tgacaatcga tagccgtcgc ttaatcgaaa
     3061 gatggaaaaa agaaggaaaa tcaaatagag aaattgcctc tctacttgga aaagctcctc
     3121 aaactatcca cactaaaatc aagcgtagga cagtccgaaa atgtcttgga aaagggcgct
     3181 tcaaagaggt ttattctgcc gactatgctc aacagtctta tgaaaataat cgcaagcact
     3241 cggtcaagag atcaagcgtg accaaggaac taaaggaaaa gattctccac tatcataacc
     3301 aaaaatttt
//
LOCUS       DAVBCA010000100         3287 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.100, whole genome shotgun sequence.
ACCESSION   DAVBCA010000100 DAVBCA010000000
VERSION     DAVBCA010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3287)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3287)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3287
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.100"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..327
                     /locus_tag="VQU19_002041"
     CDS             <1..327
                     /locus_tag="VQU19_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET2481222.1"
                     /translation="VKETSDTANGSLSPSNSGSGVTPMNHNHATGTTDSMPADTMTSS
                     TNTMAGENMAASANKMSDTMMSEDKAMLPNTGETQTSMASIGFLGLALAGLLGGLGLK
                     NKKEEN"
     gene            494..1192
                     /locus_tag="VQU19_002042"
     CDS             494..1192
                     /locus_tag="VQU19_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2481223.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            1189..2241
                     /locus_tag="VQU19_002043"
     CDS             1189..2241
                     /locus_tag="VQU19_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HET2481224.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVTKLEKGQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            2436..3047
                     /gene="rpsD"
                     /locus_tag="VQU19_002044"
     CDS             2436..3047
                     /gene="rpsD"
                     /locus_tag="VQU19_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HET2481225.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
BASE COUNT          995 a          631 c          740 g          921 t
ORIGIN      
        1 gttaaagaaa catcagacac agcaaatggt tcattatcac cttctaactc tggttctggc
       61 gtgactccga tgaatcacaa tcatgctaca ggtactacag atagcatgcc tgctgacacc
      121 atgacaagtt ctaccaacac gatggcaggt gaaaacatgg ctgcttctgc taacaagatg
      181 tctgatacga tgatgtcaga ggataaagct atgctaccaa atactggtga gactcaaaca
      241 tcaatggcaa gtattggttt ccttgggctt gcgcttgcag gtttactcgg tggtctaggt
      301 ttgaaaaaca aaaaagaaga aaactaatca gctaaggaaa taaatgatgg atagtgggct
      361 gactaagatt agtttaacaa ctcaatcagc aatcaggact ttctttcaat agcagattaa
      421 aatcatcgta aaacaataaa aatagtgtta tacttaaagc agtatagcac tgtttttatc
      481 aaaggagaga cagatgggaa agacaatttt actcgttgac gacgaggtag aaatcacaga
      541 tattcatcag agatacttaa ttcaggcagg ttatcaggtc ttggtagccc atgatggact
      601 ggaagcgcta gagctgttca agaaaaaacc gattgatttg attatcacag atgttatgat
      661 gcctcggatg gatggttatg atttaatcag tgaggttcaa tacttatcac cagagcagcc
      721 tttcctattt attactgcta agaccagtga acaggacaag atttacggcc tgagcttggg
      781 agcagatgat tttattgcta agccttttag cccacgtgag ctggttttgc gtgtccacaa
      841 tattttgcgc cgccttcatc gtgggggcga aacagagctg atttcccttg gcaatctaaa
      901 aatgaatcat agtagtcatg aagttcaaat aggagaagaa atgctggatt taactgttaa
      961 atcatttgaa ttgctgtgga ttttagctag caatccagag cgagttttct ccaagacaga
     1021 cctctatgaa aagatctgga aagaagacta cgtggatgac accaatacct tgaatgtgca
     1081 tatccatgct cttcgacagg agctggcaaa atatagtagt gaccaaacgc ccactattaa
     1141 gacagtttgg gggttgggat ataagataga gaaaccgaga ggacaaacat gaaactaaaa
     1201 agttatattt tggttggata tattatttca accctcttaa ccattttggt tgttttttgg
     1261 gctgttcaaa aaatgctgat tgcgaaaggc gagatttact ttttgcttgg gatgaccatc
     1321 gttgccagcc ttgtcggtgc tgggattagt ctctttctcc tattgccagt ctttacgtcg
     1381 ttgggcaaac tcaaggagca tgccaagcgg gtagcggcca aggattttcc ttcaaatttg
     1441 gaggttcaag gtcctgtaga atttcagcaa ttagggcaaa cttttaatga gatgtcccat
     1501 gatttgcagg taagctttga ttccttggaa gaaagcgaac gagaaaaggg cttgatgatt
     1561 gcccagttgt cgcatgatat taagacccct atcacttcga tccaagcgac ggtagaaggg
     1621 attttggatg ggattatcaa ggagtcggag caagctcatt atctagcaac cattggacgc
     1681 cagacggaga ggctcaataa actggttgag gagttgaatt ttttgaccct aaacacagct
     1741 agaaatcagg tggaaactac cagtaaagac agtatttttc tggacaagct cttaattgag
     1801 tgcatgagtg aatttcagtt tttgattgag caggagagaa gagatgtcca cttgcaggta
     1861 atcccagagt ctgcccggat tgagggagat tatgctaagc tttctcgtat cttggtgaat
     1921 ctggtcgata acgcttttaa atattctgct ccaggaacca agctggaagt ggtgactaag
     1981 ctggagaagg gccagctttc aatcagtgtg accgatgaag ggcagggcat tgccccagag
     2041 gatttggaaa atattttcaa acgcctttat cgtgtcgaaa cttcgcgtaa catgaagaca
     2101 ggtggtcatg gattaggact tgcgattgcg cgtgaattgg cccatcaatt gggtggggaa
     2161 atcacagtca gcagccagta cggtctagga agtaccttta ccctcgttct caatctctct
     2221 ggtagtgaaa ataaagccta aaaccccttt acaaatccag ctattcatgg taaaatggat
     2281 tttgtgtgaa atatcagcag gaaagcatga agctcgtcaa caggtgtctt atgacaagta
     2341 accttggctg tttaggcgaa gggcatctgc acgaatcagg gctttctaag tgactatttc
     2401 caccgaaata ttatttatat caggaggaca ttcatatgtc acgttataca ggaccatctt
     2461 ggaaacaagc tcgtcgcctt ggcctttcac ttacaggtac aggtaaagaa ttggcacgtc
     2521 gtaactacgt accaggacaa cacggaccaa acaaccgttc taaattgtca gaatacggtt
     2581 tgcaattggc tgaaaaacaa aaacttcgtt tcacttacgg tgtaggtgaa aaacaattcc
     2641 gtaacttgtt cgtacaagct acaaaaatca aaggcggaat cctaggtttc aactttatgc
     2701 ttcttttgga acgtcgtttg gataacgttg tttaccgtct tggtctcgcg actactcgtc
     2761 gtcaagctcg tcaattcgta aaccacggtc acatccttgt tgacgggaaa cgcgttgata
     2821 tcccatcata ccgcgtaact ccaggtcaag tgatctcagt tcgtgaaaaa tcattgaaag
     2881 ttccagcaat ccttgaagca gtagaagcta ctcttggacg tccagcattc gtatcattcg
     2941 acgctgaaaa attggaaggt tcattgactc gcttgccaga acgcgacgaa atcaacccag
     3001 aaatcaacga agcacttgtc gttgaattct acaacaagat gttgtaatat tttattgaat
     3061 aagacaggct ttgaggcctt gatattaagc actttgggac gttctccctt agtgcttttt
     3121 tgatttctct tagtatccag ctataatcgt ttagacataa ctagaccgat atagtccaaa
     3181 gtgatatagt aaaatgaacc aaaaatagta cacaatgtgg tataatcctt ttatggcata
     3241 ttcaatagat tttcgtaaaa aaattctctc ttattgtgag cgaacag
//
LOCUS       DAVBCA010000101         3005 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.101, whole genome shotgun sequence.
ACCESSION   DAVBCA010000101 DAVBCA010000000
VERSION     DAVBCA010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3005)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3005)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3005
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.101"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            101..1078
                     /locus_tag="VQU19_002045"
     CDS             101..1078
                     /locus_tag="VQU19_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HET2481226.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLAG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFEKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGVRFEAEK"
     gene            1075..2157
                     /locus_tag="VQU19_002046"
     CDS             1075..2157
                     /locus_tag="VQU19_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET2481227.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFELLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(2221..3005)
                     /locus_tag="VQU19_002047"
                     /pseudo
     CDS             complement(2221..3005)
                     /locus_tag="VQU19_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT          931 a          668 c          541 g          865 t
ORIGIN      
        1 aaagctaata gcttatttga aattttctcc tctctgttgg atagtcccgt ctatctatgt
       61 tataatgaaa gaaggattta aaatcggaaa aggagtattt atgctaaaat taggtgtcat
      121 cggaactggc gctatcagcc atcatttcat agaagcagcc cataccagtg gagaatacca
      181 actggtcgca atctattcta gaaaactaga aactgcagca acctttgctt ctcgctatca
      241 gaatatccaa ctattcgatc aattagaagt cttcttcaaa tcttcttttg atttagtcta
      301 tatcgccagt ccaaactcct tacattttgc tcaggcaaaa gctgccttgt ctgctggtaa
      361 acatgttatt cttgaaaagc cagctgtcac tcaaccacaa gaatggtttg atttgattca
      421 aacagctgaa aaaaataact gttttatctt tgaagcagct cgtaattatc acgagaaagc
      481 ctttactact atcaaaaact ttttagcaga taagcaagtg ttaggagcag atttcaacta
      541 tgccaaatac tcttccaaga tgcctgactt attggctgga caaacaccaa atgtcttttc
      601 agaccgtttt gctggtggag ccctcatgga tttggggatt tatcccctct atgctgctgt
      661 tcgtcttttt gaaaaagcta atgacgcgac ttaccatgct caacagcttg acaatagcat
      721 tgacctaaat ggagatggta tcctcttcta cccagactat caagttcaca tcaaggctgg
      781 aaaaaacatc acttccaatc ttccttgcga gatttataca acagatggaa ccttgactct
      841 caacacgatt gagcatattc gctcagctat ttttaccgac caccaaggaa atcaagtcca
      901 gcttcctatc caacaggctc ctcatacgat gactgaggaa gtcgctgcat ttgcacacat
      961 gatccagcaa ccagatctga atctctacca aacttggctg tatgatgcag gctctgttca
     1021 tgagctacta tataccatgc gccagactgc tggcgttaga tttgaggcag aaaaatgaaa
     1081 accaaactac cgactgaatg gcaagaactg agtgaccaac tcggtttcca agaattcacc
     1141 cccattcaaa ctcaactatt tgagctcctt cttgctggag aaaacctcct aggagtgagc
     1201 caaaccggaa ctggtaagac cctagcgtat ctcctaccaa gtcttctcag actacaaaag
     1261 aaaaaagccc aacaactctt gattctagca ccaaacacgg aacttgctgg acagattttt
     1321 gatgtatgta aaacgtgggc agaagctatc ggattgactg ctcaactctt cctttcaggt
     1381 tcaagtcaga aacgacaaat tgaacgtctt aaaaaggggc cagaaattct gattggaact
     1441 cctggccgta tctttgaact cattaaactt aaaaaaatca agatgatgaa tgtggaaacc
     1501 atcatcctgg atgaatttga ccaattacta gatgattctc agattcactt tgtagagaaa
     1561 atcactcact acgcacctcg tgaccaccaa ctggtctaca tgagtgccac gaccaagttt
     1621 gaccaagaaa agattgtgcc gaatacacgc actattgatc tctctgatca aaaattggac
     1681 aatatccagc atttctacat gcaggtagac caacgtcatc gagtggatat gctacgaaaa
     1741 ctggctcatg tagaggattt ccgtggtcta gtcttcttca atagcctgtc agaccttggg
     1801 aatgccgagg aaaaactaca gtatcgtgat atattggctg tttccctcgc tagtgatgtt
     1861 aatgttaaat ttagaaaaat catcttagaa aagtttaaag ataaccaact aaccctgctt
     1921 cttgcaactg accttttggc tcgtggaatt gatatcgata gcctagaatg tgtcgtaaac
     1981 tttgatattc ctagagatag cgaaacctac acacaccgtg ctggccgtac tggtcgtatg
     2041 ggcaaggaag gttatgttat cactctcgtc actcatccag aagaaatcaa aaaacttaaa
     2101 aagtttgcaa gtatccgaga aattgtccta aaaaaccaag aactctatat caaataaagc
     2161 cccattgctc tatacacatc cagtgtatgg agctttttta taagcaattc aattttatac
     2221 tcatctgctt tcaaaaagca ttctagtcca tctccgatta acgatggact ttatcacctc
     2281 cttctccaat ccttgtatga catcttgaag ttgattcatg acatcttcca aaattcgaaa
     2341 ggctttattc ttaaatccac gtttacgaat ctctttccac acttgttcaa tggggttcat
     2401 ctctggtgtg tatggaggaa taaatgcaaa accaatatta gtcggaatct ttaagatact
     2461 tgatttatgc catatagcat tgtccataac gagtaaaaaa taatcatctg gataagcttg
     2521 tgaaagcttt tctaaaaagg cgttcatcca ctcagtatta catctaccag ctattaagaa
     2581 aaatgattcg cctgtatggg catcaacagc tccataacaa tagcgaaatt ctcgtatata
     2641 gtgactatgg atatgtggac ctactcctat tggagcccaa caagatccca gtttactgat
     2701 tctaccgaaa ccagcctcat cttggtacat caagcgaacc ttacgaaaac gtctactata
     2761 tttaaaacgc tttcttgtct tcttgaattg agattttatt tttagacgcg acaatggttt
     2821 gagcgtctgc tttcttagga tgttctggac gtggcataat atttcgccaa ccatggcgct
     2881 tcaacagttg atagaaggca tcacgtgtgt aggaacgacc taactccttt ttataagcct
     2941 gaaataaggc atcaattgta acaaattctc ctgcctctgc agccttcaaa tggcgggcaa
     3001 gaaag
//
LOCUS       DAVBCA010000102         2694 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.102, whole genome shotgun sequence.
ACCESSION   DAVBCA010000102 DAVBCA010000000
VERSION     DAVBCA010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2694)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2694)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2694
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.102"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            276..590
                     /locus_tag="VQU19_002048"
     CDS             276..590
                     /locus_tag="VQU19_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2481228.1"
                     /translation="MWVLGFILFLIFFYSNDSKKIKKLEKKIKRLERKEKGNAEMSRL
                     LQEMIGKEPIITGVYIGPDNWEVVDVDEEWVKLRRVDNTGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            600..806
                     /locus_tag="VQU19_002049"
     CDS             600..806
                     /locus_tag="VQU19_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2481229.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            806..1003
                     /locus_tag="VQU19_002050"
     CDS             806..1003
                     /locus_tag="VQU19_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2481230.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVIEWIEKKSKNLASEKGE"
     gene            1059..1739
                     /locus_tag="VQU19_002051"
     CDS             1059..1739
                     /locus_tag="VQU19_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HET2481231.1"
                     /translation="MGMFVGMFKARVESHEIILDVKALMPWISAICLLIGFISMFLTF
                     NFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAFNITGVVIPLAIFISLSEV
                     IILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLEFFATPKDVLNYINSYDEG
                     ERQANLEQSFRILFQLHQYVLPALYIFLIILSFLTGEIQLLAFLLVGAIHVYINVMQL
                     PMVKRYFK"
     gene            1751..2392
                     /locus_tag="VQU19_002052"
     CDS             1751..2392
                     /locus_tag="VQU19_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2481232.1"
                     /translation="MKLLKNLGWFLLALLSFFFIYGFIQGLATASLALGASPYAVTLL
                     YVVLAGVYVYGIYKWYQKAPVYIEKSGFNRFIWLPALVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            2410..2640
                     /locus_tag="VQU19_002053"
     CDS             2410..2640
                     /locus_tag="VQU19_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2481233.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
BASE COUNT          791 a          442 c          559 g          902 t
ORIGIN      
        1 gatagaactg acgaagtcag ctcaaaacat ggttttgagg ttgtagatga aactgacgaa
       61 gtcagtaacc atacctacgg caaggtgaag ctgacgtggt ttgaagagat tttagaagag
      121 tattaatgat agataaagtg gtcaggaacc tactcctgac ctttttcttt tgcaaaatga
      181 caaaaatcat aatttttttg acaactatac ttgtcaaaaa gaaaaagatg tgttacaatg
      241 taagcaagtt aagagaaaag aagaaaggag ctatgatgtg ggtactaggg tttatactat
      301 ttctgatttt cttttattct aatgattcta aaaaaatcaa gaaactagag aagaaaatca
      361 aaagacttga gcgaaaagag aaaggaaatg cagaaatgtc gagattatta caagaaatga
      421 ttggaaagga accaattata acgggagtgt atattgggcc agataactgg gaagttgtgg
      481 atgttgatga ggaatgggta aagctacgac gtgtagataa tacgggaaaa gaaaaattca
      541 agttgcaacg tattgaggat atccaaaccg ttgaatttga cggagagtag gtgtgtaaca
      601 tgcaactaaa aaatcgtcta aaagagcttc gagctcgcga tggtctcaat caaaccgacc
      661 tagccaaact ggcaggggtt tccagacaga ccattagcct actagaacgg gatgagtaca
      721 ccccatccat tatcattgcc ctgaaaatat ctcaaatttt caacgaaaca gtcgaatcgg
      781 tatttcgttt ggaggaggac gagtgatgaa caagtataaa gtgatttatt atgtagtggt
      841 catagcttta ttagtcagcg tatttctact gattgggatg gacctaagct ggtttaatcc
      901 ctatcaaagc gaccaatttg tttgggtcta ctttgctctc atcccagtaa ttgaatggat
      961 tgaaaagaaa tccaaaaatc tagcaagtga aaaaggagaa tgaatatgaa aaagaaacgt
     1021 agattgttat ttttgatgtc tattgtcttg gggggttctt gggcatgttt gtagggatgt
     1081 ttaaggcacg tgtcgaatcc cacgaaatta ttttagatgt aaaagccttg atgccatgga
     1141 tatcagctat ttgtttactg ataggtttca ttagtatgtt tttgactttc aatttcttaa
     1201 agaaaagcag aaaatttcat tccttgtatc aagaggaaat ggatgacgat ctgaatgaaa
     1261 cctattatgt gcaaatgtat cggaatcttg agtttggaac cattgctttt aatattacag
     1321 gtgtagtgat tccattggct atttttattt cattaagtga ggtgattata ttgcatacaa
     1381 accctcaaac atttttcctt tctttcttac tctttgtggt attcttagtc gctcaaaaat
     1441 ctctttttaa aaccattgcg attgttcgtc agtttgattt ggaatttttc gctacaccaa
     1501 aggatgtctt gaactatata aattcttatg atgaagggga gcgtcaggct aatttggaac
     1561 agagttttcg aattttattc caattacacc aatatgtctt accagcctta tatatttttc
     1621 ttattatcct ttctttcttg acaggagaga ttcagttact agctttcttg cttgtaggag
     1681 ccatccatgt ttatatcaat gtgatgcagt tacctatggt aaaacgttat ttcaaataaa
     1741 ggagttatct atgaaattac ttaaaaacct tggctggttt cttctagccc ttctatcctt
     1801 tttctttatc tatggcttta ttcaggggct cgcgactgcg tcgcttgctt taggcgcttc
     1861 accctatgct gttactctac tctatgtggt cttggctgga gtatatgtgt acggcattta
     1921 caaatggtat cagaaagctc ctgtttatat tgagaagagc ggctttaacc gatttatttg
     1981 gcttcctgcc ttggtttggt tcttatctct ggtcgttcaa ttcttcttgc cagatgatcc
     2041 ttcagtaaat cagcaaatag cgacagactt gaccttgtct caaccacttt tctcattctt
     2101 tgctgtggtt atttttgctc ctttgacgga agagattgtt tttagaggga tgttagcacg
     2161 ctatctcttt cctaagcagg acaatagtaa acgaaccctg atttttcttc tggtatctag
     2221 tcttctattt gccttgattc attttccagg tgatgtgcaa caattttttg tctattttag
     2281 ccttggtttt agtttgggtt tggcttacat tagcagaaaa ggtctggtct acagtatttc
     2341 tcttcacgct ttgaataatt tagtcggctt tttgatgatt ctcatgctat aatagagtca
     2401 ggaggtcaca tgaaacgagt aattttatta gcagtgattc aggcagtcgt tctatttttc
     2461 atcattggag cgctagctta tgccttcaaa ggcgatttct tctataacta tctagcagtt
     2521 gtctttgctc ctattgcagg tgtactgcgt tttgggacgg cttacataac ggaaattgtc
     2581 ttgcctcgaa aggcagccga aatcgctgaa aagcgtaaag caggcaaaaa ttcaaaataa
     2641 aagagtccgg tgaagttcat cggatttttg tattatactc aatgaaaatc aaag
//
LOCUS       DAVBCA010000103         2609 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.103, whole genome shotgun sequence.
ACCESSION   DAVBCA010000103 DAVBCA010000000
VERSION     DAVBCA010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2609)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2609)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2609
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.103"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..661
                     /locus_tag="VQU19_002054"
     CDS             <1..661
                     /locus_tag="VQU19_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2481234.1"
                     /translation="FYLNKGKVYGFVGPNGAGKTTIIKMILGILKPDSGKITIFNQTV
                     EQNSKNILSRIGLVLGPSFYGHLDAYKNLKLIANMKGLSLDTERLNEYLSMVGLKDVK
                     KKKVKNFSMGMKQRLSIAASLLGSPEILIWDEPINGLDPQGVIEIRSLIRFLQEKKGI
                     TFLISSHILSELDKVISDIIIINYGKVEFFGSCHYLLQKYNCRNLEEAYLACLAGGEY
                     D"
     gene            654..1391
                     /locus_tag="VQU19_002055"
     CDS             654..1391
                     /locus_tag="VQU19_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2481235.1"
                     /translation="MIKLEFLKQKKSILWFVLIFPIILNALLYIDLTFRYRGYLLVHQ
                     NELALSNWQLIFKEQTIFYFSELFYLVLSLIIYEVFAVEFKNDAWLTVISLPFRNKYT
                     INSKLLITVVYTFTFWLSDYISLYVIGKAIDNSLEIGLIFFLKTFTIQLISSLMIMLL
                     YFLTLVLIRKISGIIPIGIIMMILTISIYYNDYNFKIYLPFTYLSHAFRVTESQFYMI
                     LLSNIIIIVLFYILIRKLNERSFEMKL"
     gene            1404..2129
                     /locus_tag="VQU19_002056"
     CDS             1404..2129
                     /locus_tag="VQU19_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2481236.1"
                     /translation="MKLLKNELIKSKIFLFIIVDICIQILVILAIKTYILDISAPYSE
                     LDYNKYWYVLHALIYMPMIFPIQILYQNLREALIEDNNNGWNIMVINTNNLVKIIYIK
                     VTINIVRCFICYFVYTIFSLIQLGGMGTDMLLTNIIFPNIIFPNIMSFLLFLPIAIFM
                     QICCIRFDSILAKALPNILLILIVLITFQSDWNIFIPATYYYTEIQSTTNLGIKLLVC
                     IWIMGFEFSLLPKLIKLKEQNLV"
BASE COUNT          908 a          317 c          388 g          996 t
ORIGIN      
        1 attttattta aataagggaa aagtatatgg ttttgttgga ccaaatgggg ctggaaaaac
       61 tacaattatc aaaatgattc tagggatttt aaaaccagat tctgggaaaa taactatttt
      121 taatcaaacc gtagaacaga attccaaaaa tatattatct aggataggat tagttttggg
      181 accttcattt tatggtcatc ttgatgctta taaaaatttg aagttaatag caaatatgaa
      241 agggcttagt ttagatactg aaagacttaa tgaatatcta tcaatggtag gattaaaaga
      301 tgttaaaaag aaaaaagtga aaaatttttc aatgggcatg aaacaacgtc taagtatagc
      361 tgcatcattg ttaggtagtc cagaaatatt aatttgggat gaaccaatca atggacttga
      421 tccacagggt gtaattgaaa ttagaagttt aatccgtttt ctacaggaga aaaaaggtat
      481 tacattttta atatcaagtc atattcttag tgaactggat aaagtgatat ctgatattat
      541 aattataaat tatgggaaag ttgaattttt tggttcttgc cactaccttt tacaaaagta
      601 taattgtcga aatctggaag aagcctactt agcttgttta gctggaggtg aatatgatta
      661 aattagagtt tctaaagcag aaaaaaagca tcttatggtt tgttcttatt tttccaataa
      721 ttctgaatgc tttgttatat atagacttaa cttttaggta tcgaggttat ttattggtgc
      781 atcaaaatga acttgcttta tctaattggc agttaatttt taaagaacaa acaatatttt
      841 atttttctga actattttat ttagttctat ctttaataat ttacgaagtg tttgcagtag
      901 aatttaaaaa tgatgcatgg ttaaccgtaa tttcattgcc atttagaaac aagtacacaa
      961 taaattctaa attactcatt acagtggttt acacatttac tttttggttg tctgattata
     1021 ttagcttata cgttattggg aaggctattg ataacagttt agagattggt ttgattttct
     1081 ttttaaaaac atttaccatt caattaattt cctcgttgat gataatgtta ttatattttc
     1141 taactttagt acttataagg aaaatttctg gaataatacc aattggtatt ataatgatga
     1201 ttttaacaat tagcatatac tacaacgatt ataattttaa gatttactta ccatttactt
     1261 atctttctca tgcttttaga gtgactgaaa gtcaatttta tatgatttta ctatctaata
     1321 taataatcat cgtacttttt tatatattaa ttcgtaaatt gaacgaaaga agttttgaga
     1381 tgaaacttta ataggtaata aaaatgaagt tacttaaaaa tgaattgatt aagagtaaaa
     1441 tatttttatt tattattgtt gacatctgta ttcagattct agtcattcta gctataaaaa
     1501 catatatttt agatatttcg gcaccatact cagagcttga ttataataag tattggtatg
     1561 ttttacacgc tttaatatat atgccaatga tttttcctat acaaattttg tatcaaaatc
     1621 taagagaggc attgattgaa gataataata atggttggaa tatcatggtg attaacacta
     1681 ataatctcgt gaaaatcatc tatataaaag taacgataaa tatcgtgaga tgttttattt
     1741 gttattttgt ttatacaatt ttttctttaa ttcaattagg tggtatggga actgatatgt
     1801 tattaaccaa tataatattt cccaatataa tatttcccaa tataatgtca tttctgttat
     1861 ttttacctat agctatcttt atgcaaattt gctgtataag atttgattcc attttagcaa
     1921 aggccttacc taatattttg ctgatactta ttgttttaat cacgtttcag agtgattgga
     1981 atatatttat acctgcaact tattattata cagaaattca gtcaactaca aacttaggta
     2041 ttaaattatt agtttgtatc tggattatgg gatttgaatt ttcccttctt ccaaaactaa
     2101 taaaattgaa agaacaaaat ctagtttaaa tgttgctcga aaattaaata attgaatacg
     2161 attaacaatg aaacaataca acgtgagtca tgacttcaaa gtaattgatt ttatgattct
     2221 ggtttcttac gcttaattaa gcaagttgta ttcactttat caaattgtta ttactctaaa
     2281 aagcgtctaa cagctataga gtgtctgttt gcttctcttt acttttattt taaataattc
     2341 attaaccttc cgtaagtgcc caataataag gtgtgttgaa gaagtctgag ataaaatagt
     2401 tctcagtcac aaaaaaagct atagattccc attggtgaac agctccctgt caagtagaca
     2461 gtaaaataat ataaaatctt aagcgacctg attcctgaat tccagtggag tcaggttgtt
     2521 ttttaaccgt ctttcttaat attgtctcac ctataataga tatgcttatg agatatgttt
     2581 aataaattaa ttttagttca aaatgtcca
//
LOCUS       DAVBCA010000104         2607 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.104, whole genome shotgun sequence.
ACCESSION   DAVBCA010000104 DAVBCA010000000
VERSION     DAVBCA010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2607)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2607)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2607
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.104"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            114..1031
                     /locus_tag="VQU19_002057"
                     /pseudo
     CDS             114..1031
                     /locus_tag="VQU19_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001822901.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
     gene            complement(1071..2015)
                     /gene="manA"
                     /locus_tag="VQU19_002058"
     CDS             complement(1071..2015)
                     /gene="manA"
                     /locus_tag="VQU19_002058"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HET2481237.1"
                     /translation="MSEPLFLQSVMQEKIWGGTKLRDEFGYDIPSEKVGEYWAISAHL
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDALLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTIKADDLRSTILVSNDFFAVYKWEITGKVNFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGRHFILPSDVESWTLEGQDLELIVSHP"
     gene            complement(2147..2428)
                     /locus_tag="VQU19_002059"
     CDS             complement(2147..2428)
                     /locus_tag="VQU19_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HET2481238.1"
                     /translation="MDTPDENGYVADDYRITYLEAHIKAMRDAIYKDGVDLLGYTTWG
                     CIDSVSAGTGEMNKRYGFIYVDRDNVGNGTLKRSKKKSFYWYMSFIAMV"
     gene            2493..>2607
                     /locus_tag="VQU19_002060"
     CDS             2493..>2607
                     /locus_tag="VQU19_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HET2481239.1"
                     /translation="MKSTKEEIQTIKTLFKDSRTAKYHKCLQIILFRLMGKS"
BASE COUNT          698 a          606 c          477 g          826 t
ORIGIN      
        1 aaaagtcgtg cgctgaacac caacaagacg cttaaatcgt gcatcagtta gttgtttact
       61 tgcttcatca ttcatagaac tactatgcca tattttgttt cgcaggaagt ctgatcattt
      121 caaatccagc cattgctcta ggagctcaag cgacctttat cctattgaat atcttcattg
      181 tatcacgtgg ggttcaaaaa gggattgaaa gagcttcgaa agtcatgatg cccctgctct
      241 ttatcatctt tgtcgtcatc atcgaacgct ctctcagttt gccaaatgcc atggaagggg
      301 ttctttactt cctcaaacca gatttttcaa aactgactag cgctggtctc ctctatgctc
      361 tgagacaatc tttctttgcc ctctcactag gggttacagc catgttgacc tatgcttctt
      421 acttggacaa gaaaaccaat ctggtccagt caagaatctc catcgtagcc atgaatatct
      481 cggtatccat catggcaggt ctagccattt tccaagctcg gtcccccttc agactgaata
      541 ttgaaggggg accgagcttg gtctttatcg tcttgcctca actctttgac aagatgcctt
      601 ttggaaccat tttctatgtc ctcttcctct ttgcgactgt cacttcttct gtcgttatgc
      661 tggaaatcaa tgtagacaat atcaccaatc aggacaacag caagcgtgct aaatggagtg
      721 ttattttagg aattttgacc tttgtctttg gcattccttc agccctatct tacggtgtca
      781 tggcggatgt tcacattttt ggtaaagcct tctttgacgc tatggacttc ttggtttcca
      841 atctcctcat gccatttgga gctctcttcc tttcactttt tacaggctat atctttaaaa
      901 aggctcttgc aatggaggaa ctccatctcg atgaaagagc atggaaacaa ggactgttcc
      961 aagtctggct cttccttctt cgtttcgtca ttccaatcat catcgtggtc ttcatcgccc
     1021 aatttatgta atcaaaagga cttgagtaat gaactcaggt cctttctttt ttatggatga
     1081 ctaacaatta attctaaatc ttgcccttct agagtccaag attcaacatc acttggtagg
     1141 ataaagtgtc tccctttttg gattggatag tttttcccgt caacagttag ttgaccttga
     1201 ccagccaaga cactcaacaa gctgtagtca gctgtctttt caaagttaac ttttccagta
     1261 atttcccatt tgtaaactgc gaagaaatca ttggatacaa ggatagtgga acgtagatca
     1321 tctgctttga ttgtcactgg acggctattt gcgggttcac caatgttcaa gacatcgata
     1381 gatttttcaa ggtgaagttc acgtaaattg cccttgtcat ccttacggtc aaagtcatag
     1441 acacggtaag tggtatcgct agactgctgg gtttcaagaa tcaagatacc cgccccgata
     1501 gcgtgcatgg taccgcttgg tacatagaag aaatctcctg ctttaactgg cacttttgtc
     1561 aacagcgcat cccagttctt atcctcgatt tgctggcgga gttcttcttt tgacttggca
     1621 ttgtgaccgt agataatctc tgaaccttca tctgctgcaa tgatgtacca acattctgtt
     1681 tttccaagtt cgccttcatg ctcgagtcca taagcatcgt ctgggtgaac ttggacactg
     1741 agccagtcgt tggcatcgag gatcttggtc aaaagtggaa atacaggttc tggacgattg
     1801 ccaaataatt cacggtgttc cgcatacaaa gtagcaagat ctgttccctc gtaacgacca
     1861 ttggcaactt tagaaacacc atttagatga gctgagatag cccagtactc tccgactttt
     1921 tcacttggga tgtcgtagcc aaactcatca cgtagcttgg taccacccca gattttttct
     1981 tgcataactg attgtaaaaa taatggttct gacatcttaa tctcctgtct gatttttctc
     2041 ccctcattat agcaaaaaaa gagttccatt tgaactcttt tttacatctt ataaagcagg
     2101 gagaagattt tataaaaata gtaaacaaat gtgctctact cgatgcttac accattgcta
     2161 taaatgacat gtaccaatag aaggacttct tcttgctacg tttgagagtc ccatttccta
     2221 cattatctcg atctacatag ataaagccat agcgcttatt catttcccct gtgccagctg
     2281 aaaccgaatc gatacagccc catgtcgtat aaccaagcaa gtcaaccccg tctttgtaaa
     2341 tggcatctcg catggccttg atgtgggcct ctaagtaagt aatccgatag tcatctgcta
     2401 cataaccatt ctcatccggt gtatccatag caccgagtcc attttctacg ataatactat
     2461 actaaaatca aaaagcatta tataatagtg atatgaaatc aactaaagaa gaaatccaaa
     2521 ccatcaaaac actttttaaa gactctcgta cagctaaata tcataaatgc cttcaaatca
     2581 ttctatttcg tctgatgggc aaatctt
//
LOCUS       DAVBCA010000105         2398 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.105, whole genome shotgun sequence.
ACCESSION   DAVBCA010000105 DAVBCA010000000
VERSION     DAVBCA010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2398
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.105"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(26..428)
                     /locus_tag="VQU19_002061"
                     /pseudo
     CDS             complement(26..428)
                     /locus_tag="VQU19_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(373..555)
                     /locus_tag="VQU19_002062"
     CDS             complement(373..555)
                     /locus_tag="VQU19_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HET2481240.1"
                     /translation="MDLKFEGVDLEYKKAKNNLPESFWETYSAFANTNGGKIILGIDE
                     KNIDTYQRVNRLPAKL"
     gene            912..>2398
                     /gene="pcpA"
                     /locus_tag="VQU19_002063"
     CDS             912..>2398
                     /gene="pcpA"
                     /locus_tag="VQU19_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HET2481241.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDGA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEI
                     HIKNKSTEFSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETD
                     VAKPKKNSNQGVVGWVKDKGLWYYLNESGSKATGWVKDKGLWYYL"
BASE COUNT          837 a          359 c          397 g          805 t
ORIGIN      
        1 tgagccttca tagcgtggca tttcttttta cttccgtcac atcaatcatt accgtgtcct
       61 cagaactgag aggagttctt gaaatcgtaa caccaccttt gaacaagagt tacttcaacc
      121 cattagctcc gacggattaa gttgctttcg tgaataccaa aatcagccgc aatttcttca
      181 taagtgcggt attctcgcac atattgaaga gtggccataa gaaggtcttc taggcttaat
      241 ttaggttttc gtccaccttt tgtgtgttta agttgataag ctgtttttaa cacagctaac
      301 atctcttcaa aagtggtgcg ctgaacacca acaagacgct taaatcgtgc atcggttagt
      361 tgtttacttg cttcataatt tcgcagggag tctattgact ctttggtagg tgtcaatgtt
      421 tttttcatct atcccgagaa ttattttccc gccatttgta tttgcaaatg ctgagtaggt
      481 ttcccagaaa gactctggaa gattgttttt agcttttttg tattctaaat caaccccttc
      541 aaattttaag tccatatttt tcctttacat ctgttttttg tggttctggt atttgttcaa
      601 gttgagtgat aatatagcga attgaatttc gagagttttt actcagttaa tttctttttt
      661 aacccacttt aatttctttt ttaacccact ttaatttctt ttttaacacg ggttaaaaaa
      721 gaaattaaag tgggttaatt tttcttgact taaaatttaa aaatgatata ctgtgtttat
      781 ggagagatga caatttataa aatgtactac tctattctac tagataatga ttgaataaaa
      841 ctttttataa caacggctag caaagttata attttatatc tattagaaaa taaatatgta
      901 aggaaattta aatgaaaaaa actacaatat tatcattaac tacagctgcg gttattttag
      961 cagcatatgt ccctaatgaa ccaatcctag cagatactcc tagttcggaa gtaatcaaag
     1021 agactaaagt tggaagtatt attcaacaaa ataatatcaa atataaggtt ctaactgtag
     1081 aaggtaacat aggaactgtt caagtgggta atggagttac tcctgtagag tttgaagctg
     1141 gtcaagatgg aaaaccattc acgattccta caaaaatcac agtaggtgat aaagtattta
     1201 ccgttactga agtagctagt caagctttta gttattatcc agatgaaaca ggtagaattg
     1261 tctactatcc tagctctatt actatcccat caagcataaa aaaaatacaa aaaaaaggct
     1321 tccatggaag taaagctaaa actattattt ttgacaaagg cagtcagctg gagaaaattg
     1381 aagatggagc ttttgatttt tctgaattag aagagattga attgcctgca tctctagaat
     1441 atattggaac aagtgcattt tcttttagtc aaaaattgaa aaagctaacc ttttcctcaa
     1501 gttcaaaatt agaattaata tcacatgagg cttttgctaa tttatcaaat ttagagaaac
     1561 taacattacc aaaatcggtt aaaacattag gaagtaatct atttagactc actactagct
     1621 taaaacatgt tgatgttgaa gaaggaaatg aatcgtttgc ctcagttgat ggtgttttgt
     1681 tttcaaaaga taaaacccaa ttaatttatt atccaagtca aaaaaatgac gaaagttata
     1741 aaacgcctaa ggagacaaaa gaacttgcat catattcgtt taataaaaat tcttacttga
     1801 aaaaactcga attgaatgaa ggtttagaaa aaatcggtac ttttgcattt gcagatgcga
     1861 ttaaacttga agaaattagc ttaccaaata gtttagaaac tattgaacgt ttagcctttt
     1921 acggtaattt agaattaaaa gaacttatat taccagataa tgttaaaaat tttggtaaac
     1981 acgttatgaa cggtttacca aaattaaaaa gtttaacaat tggtaataat atcaactcat
     2041 tgccgtcctt cttcctaagt ggcgtcttag attcattaaa ggaaattcat attaagaata
     2101 aaagtacaga gttttctgtg aaaaaagata catttgcaat tcctgaaact gttaagttct
     2161 atgtaacatc agaacatata aaagatgttc ttaaatcaaa tttatctact agtaatgata
     2221 tcattgttga aaaagtagat aatataaaac aagaaactga tgtagctaaa cctaaaaaga
     2281 attctaatca gggagtagtt ggttgggtta aagacaaagg tttatggtat tacttaaatg
     2341 aatcaggttc aaaggctact ggttgggtta aagacaaagg cttatggtat tacttaaa
//
LOCUS       DAVBCA010000106         2118 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.106, whole genome shotgun sequence.
ACCESSION   DAVBCA010000106 DAVBCA010000000
VERSION     DAVBCA010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2118)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2118)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2118
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.106"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            368..1714
                     /gene="gdhA"
                     /locus_tag="VQU19_002064"
     CDS             368..1714
                     /gene="gdhA"
                     /locus_tag="VQU19_002064"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HET2481242.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVVSFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSDLDAIKVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
BASE COUNT          673 a          384 c          401 g          660 t
ORIGIN      
        1 ttggatttct tctttagttg atttcatatc actattatat aatgattttt gattttagtc
       61 tggtataaat attgctttcc tccaaaatgg tcataatttt actagcaaat ctaacatatc
      121 acggataaat taacaagtga tttctgaatt gctaaacatt ttcttttctt atagcatacc
      181 atactttaag attttgtctt tgagaaagat atttccaaga aaaacgttcg tttttttatc
      241 tattttcaaa aaaaccaaaa actgaattga aagaattttt agaaaatttc tgttttttct
      301 ttacagtgaa aaaaaattct gctataatgt cttatgtaat aaaatatgac aataaaagga
      361 gaacgatatg acatctgcta aagaatatat ccaaagcgtg tttgaaactg tgaaagctcg
      421 taacgggcac gaggctgaat tcctccaagc tgttgaagaa tttttcaaca ctttagaacc
      481 tgtatttgaa aaacaccctg agtatatcga agaaaatatc ttggcacgta ttactgagcc
      541 tgagcgcgtg gtttctttcc gtgttccttg ggttgaccgt gatggaaaaa ttcaagtaaa
      601 ccgtggttac cgtgttcaat tcaactcagc tgttggacca tacaaaggtg gacttcgttt
      661 ccacccaact gtaaaccaag ggatcttgaa attcctcgga tttgaacaaa tctttaaaaa
      721 tgtcttgact ggacttccta tcggtggagg taaaggtgga tcagacttcg atcctaaagg
      781 taaaacagat gctgaagtga tgcgcttctg ccaaagcttc atgactgaat tgcaaaaaca
      841 catcggacca tcacttgacg tacctgctgg tgatatcggt gttggtggac gtgaaattgg
      901 ttacctttac ggtcaataca aacgtcttaa ccaatttgat gctggtgtct tgactggtaa
      961 acctcttgga tttggtggta gcttgattcg tccagaagca actggttacg gtttggttta
     1021 ctatactgaa gaaatgctca aagctaacgg taacagcttt gctggtaaga aagtcgttat
     1081 ttcaggttct ggtaacgttg ctcaatatgc tcttcaaaaa gcaactgaac tcggtgcaac
     1141 tgttatttct gtttctgact caaatggtta tgtcatcgat gaaaatggta tcgacttcga
     1201 tcttttggtt gatgttaaag aaaaacgtcg tgctcgtttg actgagtatg cagctgaaaa
     1261 agcaactgca acctaccacg aaggtactgt atggacttac gctggaaact atgacattgc
     1321 tcttccatgt gccactcaaa acgaaatcaa cggtgaagca gctaaacgtt tggttgctca
     1381 aggcgttatc tgtgtatctg aaggtgccaa catgccgagc gaccttgatg ccatcaaagt
     1441 ttacaaagaa aatggtatct tctacggacc tgcaaaagct gccaacgctg gtggtgtagc
     1501 cgtttcagct cttgaaatga gccaaaacag tcttcgcctc tcatggactc gtgaagaagt
     1561 tgatggccgt ctcaaagaca tcatgacaaa catcttcaac acagctaaaa cgacttcaga
     1621 aacatacggt cttgataaag actaccttgc aggagctaac attgctgcct ttgaaaatgt
     1681 agcaaatgcc atgattgcac aaggtattgt ttaagattta tttactcaat cctcaatcac
     1741 tacgattggg gatttttagc ttgaattaaa aaattggaaa atctaattaa ataaaatgaa
     1801 atgaaataaa aactgaacaa attgattgcg gaattcaaac caatttctaa catacttcta
     1861 gaaattaatt tgacttttct aatcgatttg ttcatatctt atttcaattt actatactta
     1921 cttaaccctt tttatactca atgaaaatca aagagcaaac taggaagcga gccgcaggct
     1981 gtacttgagt acggcaaggc aaagctgacg tggtttgaag agattttcaa agagtattaa
     2041 acaaaaagaa aaaccgctac tcctaagaat agcgatttaa tcatgttttt aagctactac
     2101 tgtagttgct ctattatt
//
LOCUS       DAVBCA010000107         1846 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.107, whole genome shotgun sequence.
ACCESSION   DAVBCA010000107 DAVBCA010000000
VERSION     DAVBCA010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1846)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1846)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1846
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.107"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..227
                     /locus_tag="VQU19_002065"
     CDS             <1..227
                     /locus_tag="VQU19_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HET2481243.1"
                     /translation="NRGYDVHCDAVMVKDVNEDLMKGYDIFTPIAATDLGFEPGIPVI
                     EAGPILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            275..1750
                     /locus_tag="VQU19_002066"
     CDS             275..1750
                     /locus_tag="VQU19_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HET2481244.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNIVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVVFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
BASE COUNT          524 a          374 c          373 g          575 t
ORIGIN      
        1 caaaccgtgg ttatgatgtt cactgtgatg cagtcatggt gaaagatgta aacgaagacc
       61 ttatgaaagg ttacgatatc tttacaccaa tcgctgcaac agaccttggt tttgaaccag
      121 gtatcccagt tatcgaagct gggccaatct tattccgtat cccagcaatg agcgctccag
      181 tatttgacaa tattgaagca gctattaaag aacacggatt aagctaattc taatttgtta
      241 acattcatat aacataaaaa agggaggaac tgttatggat gcaatctttg acctaatcgg
      301 aaaggttttc aatcccattt tagaaatggg tggacctgtc atcatgttaa tcattttgac
      361 agtattggct ttactttttg gagtgaaatt ctccaaagcg cttgaaggtg gtatcaaact
      421 tgccatcgct cttacaggta tcggtgctat catcggtatg ctaaatggtg ctttctcagc
      481 atcacttgca aaattcgttg aaaacactgg tatccaattg agtattaccg acgttggttg
      541 ggcaccactc gcaacaatca cttggggttc tgcttggaca ctatacttct tgctcatcat
      601 gttgattgtc aacatagtga tgctagctat gaagaaaaca gatacacttg acgttgatat
      661 ctttgatatc tggcacttgt ctatcacagg tctcttgatt aaatggtatg ctgataacaa
      721 tggtgtgagt caaggggttt cactctttat tgctacagca gctatcgtcc ttgtcggtgt
      781 gttgaaaatt atcaactctg acttgatgaa acctacattt gatgaccttc ttaacgcccc
      841 aagttcatca ccaatgacat caactcacat gaactacatg atgaacccag ttatcatggt
      901 tttggataag atttttgaaa aattcttccc aggccttgat aaatatgact ttgatgctgc
      961 taaattgaac aagaaaatcg gtttctgggg atctaaattc ttcatcggtt tcatccttgg
     1021 tatcgttatc ggtattatgg gaactccaca tccaattgca ggtgttgcag atgcagataa
     1081 atggcgtctt gttatcaaag gatggttgtc tcttggtttg actgccggtg tatctttgga
     1141 actcttctca cttatcggtt catggttcat cgcagccgta gaaccactat cacaaggtat
     1201 tacaaacgtt gctactaaac gtcttcaagg acgtaaattc aatatcggtc ttgactggcc
     1261 attcatcgct ggtcgtgctg aaatctgggc ttgtgccaac gtacttgcac caatcatgtt
     1321 gattgaagca gtgcttcttt caaaagttgg aaatggtatc ttgccacttg caggtatcat
     1381 cgctatgggt gttactccag ctctcttggt tgtaactcgt ggtaaattgc tccgtatgat
     1441 tatcttcgga acactcttgt tgccactctt ccttctttca ggtacactta ttgcaccatt
     1501 tgcaacagaa cttgctaaag gtgtaggtgc cttcccagaa ggtgtgagcc aaactcaatt
     1561 gattactcac tctactcttg aaggaccaat cgaaaaactt cttggttgga caattggtaa
     1621 cactacaact ggtgatatca aagcaatcct tggtgcagta gtcttccttg tattctatat
     1681 cggtatcttt gcttggtaca gaaaacaaat gatcaaacgt aacgaagagt acgcagcaaa
     1741 agcaaaataa tgcgctccta taaaatataa actcaatgaa aatcaaagag caaactagga
     1801 aactagccac aggttgctca aaacacagtt ttgaggttgt agataa
//
LOCUS       DAVBCA010000108         1822 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.108, whole genome shotgun sequence.
ACCESSION   DAVBCA010000108 DAVBCA010000000
VERSION     DAVBCA010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1822)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1822)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1822
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.108"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..317)
                     /locus_tag="VQU19_002067"
     CDS             complement(<1..317)
                     /locus_tag="VQU19_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000603792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2481245.1"
                     /translation="MILSKVRCYIYNSKIRGKVLYELYEFINENKQLMDAINSIKVDS
                     SNGFSIQILHLGEQQTTVLLTDFFTKTLDLFKEFRVTNKSTLEQVKNQISILNSSGPK
                     MDLT"
     gene            complement(330..1349)
                     /locus_tag="VQU19_002068"
     CDS             complement(330..1349)
                     /locus_tag="VQU19_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic biosynthesis protein"
                     /protein_id="HET2481246.1"
                     /translation="MSNTLKQLLLFREEFIKNILNGIDVDETVVIENDFVEELENFLK
                     ENDLLDFSNSIFFQLSGDKVIVNNIYPGYLAYFNRFLTFYPKIFAIKEVGEYIDFLNF
                     EKRIADMFYCWGFNANSRVLTAEKIIEIPNHQINAKYIKKVIKMSELLFGVDSNNRIR
                     LLNNRRELIKTIFQGSVIKSAIPALAATLDTISNSGSFQISLSKQIINNLVLSGKDKV
                     TIPRIELDNVVLSRQKIIVSVSYINDFLDLRFPDKIEYILNFLEGSGFNTKVMVYFGK
                     IVEEDKNYFVNLEKPQYFDFTSILFNKLFFKELNKFDYMVIEELIPNLDEDVMMTEYI
                     KEYTE"
BASE COUNT          626 a          318 c          190 g          688 t
ORIGIN      
        1 gttaaatcca tttttggacc agaagaattt agtatgctaa tttgattttt cacctgctca
       61 agagtactct tatttgtaac cctaaattcc ttaaacaagt ctaaagtttt agtaaaaaaa
      121 tctgttaata agacagttgt ttgctgttct cctaaatgta atatttgaat actaaaacca
      181 ttactactgt caactttaat tgaattaatt gcgtccatca attgcttatt ttcatttata
      241 aattcatata attcatacag aactttacct ctaattttag aattatatat gtaacaacgt
      301 actttactta aaatcataat agattgctcc tattcagtat actcttttat atactctgtc
      361 atcattacat cttcatcaag atttggaatg agttcttcaa taaccatgta atcaaacttg
      421 tttaattctt taaagaataa cttattgaaa agtatactgg taaaatcaaa atactgaggt
      481 ttttcaagat taacaaaata gttcttatct tcttctacaa ttttcccaaa gtagaccatt
      541 actttagtat tgaaaccaga tccttctaaa aaatttaaaa tgtattctat tttatctgga
      601 aatctcaaat ccaaaaaatc atttatatac gaaactgata caataatctt ctgtcttgaa
      661 agaacaacat tatctaactc tatcctagga attgtaactt tatctttacc acttaatact
      721 aaattattaa ttatctgctt tgataaagaa atttgaaatg atccactgtt actgattgta
      781 tccaaagtag cagctagagc aggaattgct gacttaatta cagaaccttg gaaaatagtt
      841 tttatcaatt cccttctatt gttaagcaac cgaattctgt tattactatc aacaccaaac
      901 aagagttcac tcatttttat aacttttttt atgtacttag cattgatttg gtgatttggg
      961 atttcaatta ttttttcagc tgtcaacact ctagaatttg cattaaatcc ccaacaataa
     1021 aacatatccg caattctctt ttcaaaattt aaaaagtcaa tatattctcc aacttcttta
     1081 atagcgaata ttttcggata aaatgtaagg aacctattaa aatatgctaa atatcctgga
     1141 taaatattat tcactattac tttatctcca gataactgaa aaaatatgct atttgaaaaa
     1201 tctagcaaat cattctcttt taaaaagttc tccaactctt ctacaaaatc attttctatt
     1261 actactgttt catccacatc aatcccattc aaaatatttt ttatgaactc ctctctaaaa
     1321 agtagtaatt gcttcaatgt atttgacata tattcatctg gataatatgt ttccaaatta
     1381 acattagcga gtctaggagc ttctttgatg attatgttaa ctatatcctg aactatttct
     1441 tctgatgtcc ctaccttctg gtgttctctc ctgtgtttat tataataaca ttgtccgaat
     1501 agtagctgaa aaaacaaatt actatcaaat aatctcgtta gaattaatag ctttcttatt
     1561 gacttattat caacttttaa actttctttt tcaatttgcc tcaactctac aatgtcttga
     1621 taaataaaat tatgttctat aaaaatttac ttcaactagc tatggtttaa tagatttttt
     1681 aaaggggata attgtctaaa atttaacttt ttacaaatca agatgtctct ataaactagc
     1741 aacctctcta ataactttac ccctatagct atagacaatc gagtagggga taatctctag
     1801 cccctctcac accaccgtac gt
//
LOCUS       DAVBCA010000109         1800 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.109, whole genome shotgun sequence.
ACCESSION   DAVBCA010000109 DAVBCA010000000
VERSION     DAVBCA010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1800)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1800)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1800
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.109"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..1545
                     /gene="phtA"
                     /locus_tag="VQU19_002069"
     CDS             <1..1545
                     /gene="phtA"
                     /locus_tag="VQU19_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HET2481247.1"
                     /translation="HVESDGLVFDPAQITSRTARGVAVPHGDHYHFIPYSQMSELEER
                     IARIIPLRYRSNHWVPDSRPEQPSPQPTPEPSPGPQPAPNLKIDSNSSLVSQLVRKVG
                     EGYVFEEKGISRYVFAKDLPSETVKNLESKLSKQESVSHTLTAKKENVAPRDQEFYDK
                     AYNLLTEAHKALFENKGRNSDFQALDKLLERLNDESTNKEKLVDDLLAFLAPITHPER
                     LGKPNSQIEYTEDEVRIAQLADKYTTSDGYIFDEHDIISDEGDAYVTPHMGHSHWIGK
                     DSLSDKEKVAAQAYTKEKGILPPSPDADVKANPTGDSAAAIYNRVKGEKRIPLVRLPY
                     MVEHTVEVKNGNLIIPHKDHYHNIKFAWFDDHTYKAPNGYTLEDLFATIKYYVEHPDE
                     RPHSNDGWGNASEHVLGKKDHSEDPNKNFKADEEPVEETPAEPEVPQVETEKVEAQLK
                     EAEVLLAKVTDSSLKANATETLAGLRNNLTLQIMDNNSIMAEAEKLLALLKGSNPSSV
                     SKEKIN"
     gene            1703..>1800
                     /locus_tag="VQU19_002070"
     CDS             1703..>1800
                     /locus_tag="VQU19_002070"
                     /inference="COORDINATES: protein motif:HMM:TIGR01363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET2481248.1"
                     /translation="MKINKKYLAGSVATLVLSVCAYELGLHQAQTV"
BASE COUNT          637 a          325 c          352 g          486 t
ORIGIN      
        1 catgtagaat ctgatggcct tgttttcgac ccagcgcaaa tcacaagtcg aacagctaga
       61 ggtgttgcag tgccacacgg agatcattac cacttcatcc cttactctca aatgtctgaa
      121 ttggaagaac gaatcgctcg tattattccc cttcgttatc gttcaaacca ttgggtacca
      181 gattcaaggc cagaacaacc aagtccacaa ccgactccgg aacctagtcc aggcccgcaa
      241 cctgcaccaa atcttaaaat agactcaaat tcttctttgg ttagtcagct ggtacgaaaa
      301 gttggggaag gatatgtatt cgaagaaaag ggcatctctc gttatgtctt tgcgaaagat
      361 ttaccatctg aaactgttaa aaatcttgaa agtaagttat caaaacaaga gagtgtttca
      421 cacactttaa ctgctaaaaa agaaaatgtt gctcctcgtg accaagaatt ttatgataaa
      481 gcatataatc tgttaactga ggctcataaa gccttgtttg aaaataaggg tcgtaattct
      541 gatttccaag ccttagacaa attattagaa cgcttgaatg atgaatcgac taataaagaa
      601 aaattggtag atgatttatt ggcattccta gcaccaatta cccatccaga gcgacttggc
      661 aagccaaatt ctcaaattga gtatactgaa gacgaagttc gtattgctca attagctgat
      721 aagtatacaa cgtcagatgg ttacattttt gatgaacatg atataatcag tgatgaagga
      781 gatgcatatg taacgcctca tatgggccat agtcactgga ttggaaaaga tagcctttct
      841 gataaggaaa aagttgcagc tcaagcctat actaaagaaa aaggtatcct acctccatct
      901 ccagacgcag atgttaaagc aaatccaact ggagatagtg cagcagctat ttacaatcgt
      961 gtgaaagggg aaaaacgaat tccactcgtt cgacttccat atatggttga gcatacagtt
     1021 gaggttaaaa acggtaattt gattattcct cataaggatc attaccataa tattaaattt
     1081 gcttggtttg atgatcacac atacaaagct ccaaatggct ataccttgga agatttgttt
     1141 gcgacgatta agtactacgt agaacaccct gacgaacgtc cacattctaa tgatggatgg
     1201 ggcaatgcca gtgagcatgt gttaggcaag aaagaccaca gtgaagatcc aaataagaac
     1261 ttcaaagcgg atgaagagcc agtagaggaa acacctgctg agccagaagt ccctcaagta
     1321 gagactgaaa aagtagaagc ccaactcaaa gaagcagaag ttttgcttgc gaaagtaacg
     1381 gattctagtc tgaaagccaa tgcaacagaa actctagctg gtttacgaaa taatttgact
     1441 cttcaaatta tggataacaa tagtatcatg gcagaagcag aaaaattact tgcgttgtta
     1501 aaaggaagta atccttcatc tgtaagtaag gaaaaaataa actaatgaaa aatgaaagtc
     1561 tcgataaaga ggctttcatt tttattatgt atatatgtaa aattcttgac aagcaatatt
     1621 aaaaagagta aactattaac tagttaatta accggtttgt tactttatag tgaatcaaat
     1681 atacttaaga aaagaggaaa gaatgaaaat caataaaaaa tatctagctg ggtcagtagc
     1741 tacacttgtt ttaagtgtct gtgcttatga actaggtttg catcaagctc aaactgtaaa
//
LOCUS       DAVBCA010000110         1652 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.110, whole genome shotgun sequence.
ACCESSION   DAVBCA010000110 DAVBCA010000000
VERSION     DAVBCA010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1652)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1652)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1652
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.110"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            109..408
                     /locus_tag="VQU19_002071"
     CDS             109..408
                     /locus_tag="VQU19_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic biosynthesis protein"
                     /protein_id="HET2481249.1"
                     /translation="MDSYAINFWESKGVGIDKKILEFIQKNITVIKNKNFLNKDFDIY
                     VKKIHNLFFVISTLVSKEQYMGIVSSQIHMFANRMGISPTIEVTMLDFFLREDSD"
     gene            410..1180
                     /locus_tag="VQU19_002072"
     CDS             410..1180
                     /locus_tag="VQU19_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SagB/ThcOx family dehydrogenase"
                     /protein_id="HET2481250.1"
                     /translation="MEKYFFDISIFEKIKKVLSYQSKYWEISKPRDKYSFKSQNRISG
                     SNSIKFKDFELDYELESLGKILLKRRSFLLNEFDKNASFDKLIYLLKTVFSPTNCKFV
                     FGEEVPLFSYPTSGALNSITPFVYIDNMDEVKNGIYEVKYDGLEFKKSMNIIDLETFT
                     PITSKNSDVQNNSFKKVNMIIMLCSNYENIFNKYGLLAYRLLHLEAGHIAQNIQLVST
                     ALGIKSLPMGGWFDDKIETFINEISDKKNIYLYAIAVG"
     gene            1200..1364
                     /locus_tag="VQU19_002073"
     CDS             1200..1364
                     /locus_tag="VQU19_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2481251.1"
                     /translation="MNAEDKFRELENENKLLKLHNKELENEIQNGWKFWIWVTVPILG
                     LIYAIIQKIF"
BASE COUNT          608 a          181 c          270 g          593 t
ORIGIN      
        1 gataactatt attacgaaaa aaaattcttg tgtaaaattc tattgacttt ctatattatt
       61 tttgtatttc ataacgaatg taatttaaca agtgaagaaa ttttaaagat ggattcctat
      121 gctattaatt tctgggagag taaaggggtc ggtattgaca aaaaaatctt ggaatttatt
      181 caaaaaaata ttacagttat taaaaataaa aattttttga ataaagattt tgatatttat
      241 gttaaaaaga ttcataattt attctttgtc atttctactt tagtttcaaa agagcaatac
      301 atggggatag tttcttccca aatacatatg ttcgcaaata ggatgggaat ttctcccacc
      361 attgaagtta ccatgctaga tttttttctg agggaggatt ctgattaata tggaaaaata
      421 tttttttgat atttctattt ttgaaaaaat aaaaaaagta ttatcatacc aatctaaata
      481 ttgggaaata tcgaagccta gggataagta cagtttcaaa agtcaaaata gaatatctgg
      541 ctctaatagc attaaattta aagattttga gttagattat gaactggagt cacttggtaa
      601 aatactttta aaaaggagat cgtttttact aaatgaattt gataagaatg cgagttttga
      661 caaactgatt tacttgttga aaactgtatt ctctcctaca aattgcaagt ttgtatttgg
      721 agaagaggtt cctttattta gctatcctac atcaggtgcg ttaaattcaa ttactccttt
      781 tgtttatatt gataatatgg atgaagtaaa gaatggtata tatgaagtaa agtatgacgg
      841 acttgaattt aaaaaaagta tgaatattat agacttagaa acatttaccc caataacaag
      901 taaaaacagt gacgtacaaa ataattcatt taaaaaggta aatatgataa ttatgttatg
      961 ttcgaattat gaaaatattt tcaataaata tggattatta gcttatcgac ttttgcattt
     1021 agaggctggt catattgcac aaaatatcca gcttgtttct actgcgctag gaataaaaag
     1081 tttaccgatg ggaggttggt ttgatgataa aatagaaact tttattaatg aaattagtga
     1141 taaaaaaaat atttatctct atgcaattgc agttggataa atttaaggag gaagtgtaga
     1201 tgaacgcaga ggataaattt cgcgaactag aaaatgaaaa taaacttcta aaacttcata
     1261 acaaggagct tgagaatgaa attcaaaatg gatggaaatt ttggatatgg gtaactgtcc
     1321 ctattttagg tttgatatat gctattattc aaaaaatttt ttaattatgc tagtttgtca
     1381 ggttgagtag tttttgttca aaatttaata aacttttttc aatgaagatt atctaaagat
     1441 tgcttctcag atgagaatgg cttctctatc ttatataaat tatcttcata gagtgtcctg
     1501 ttattcatgt tatcacagaa tagatagttt ttttggctct ataatatttg tagtgggtaa
     1561 atcccctata gatattatgg agcctatttt tgtgtagaaa aaaagtccca tatcatctat
     1621 aatgaaaagc aaccaaacta tcattagaaa ga
//
LOCUS       DAVBCA010000111         1542 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.111, whole genome shotgun sequence.
ACCESSION   DAVBCA010000111 DAVBCA010000000
VERSION     DAVBCA010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1542)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1542)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1542
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.111"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            84..491
                     /locus_tag="VQU19_002074"
     CDS             84..491
                     /locus_tag="VQU19_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET2481252.1"
                     /translation="MARYGVYAVIPNPEQKQIVLVQEPNGAWFLPCGEIEAGENHQEA
                     LKRELIEELGFTAEIGTYYGQADEYFYSRHRDTYYYNPAYLYEATSFKEVQKPLENFN
                     HIAWFPIDEAIQNLKRGSHKWAIESWKKQHKIG"
     gene            656..955
                     /locus_tag="VQU19_002075"
     CDS             656..955
                     /locus_tag="VQU19_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HET2481253.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKTSVNEANIKTLYSEKLIGISIPIK"
     gene            1216..1539
                     /gene="tnpB"
                     /locus_tag="VQU19_002076"
     CDS             1216..1539
                     /gene="tnpB"
                     /locus_tag="VQU19_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HET2481254.1"
                     /translation="MMIVLSDLGQVHLVCGKTDMRQGIDSLAYVVKTHFELDPFSGQV
                     FLFCGGRKDRFKALYWDGQGFWLLYKRFENGRLTWPSTEKDVKALTSEQVDWLMKGFS
                     ITPQI"
BASE COUNT          527 a          306 c          278 g          431 t
ORIGIN      
        1 actataataa taacgatact agataatgag gaaaatgcaa tggcaaaccc aactttcgga
       61 gaaaaaaagc gaatacagac tatattgctc gctatggcgt atatgcagtt atccctaatc
      121 ctgaacaaaa acaaattgtt cttgttcaag aaccaaatgg tgcttggttc ctaccatgtg
      181 gagaaattga agcaggtgaa aatcatcagg aagccctaaa gcgtgagttg attgaagagc
      241 ttggtttcac agcagaaatt ggtacctatt acggacaagc tgacgaatat ttctattctc
      301 gtcatcgtga tacctactac tacaatcctg cctacctcta tgaagcaact tctttcaaag
      361 aagtacaaaa gccactagaa aactttaatc atattgcctg gttccctatt gacgaggcta
      421 tccaaaacct taaacgtggt agccataaat gggccattga atcttggaaa aaacagcata
      481 agattggcta atactcttcg aaaataaaat tcaaaccacg tcagcgtcgc cttaccgtac
      541 tcaagtatag cctgcggcta gcttcctagt ttgctctttg attttcattg agtataaatc
      601 aagcgacttt attcaaaaag tgctataata gaattagaaa atcggaggaa atattatgaa
      661 gcttatcaat acgacaaact cacactcgca acttgtaaaa agtcaactag aaagtaccga
      721 tgcaaccctt gttgaggttt attctgcagg gaatacagat gttattttta cccaagctcc
      781 gcttcactat gaaatcctca tctcaaacaa acaccgtgct attcgtgagc ctgaaatcga
      841 aaccattcaa gaatttttct tgaaacgtaa aattgataag acctctgtta atgaagccaa
      901 tatcaagaca ctctactcag agaaattaat tggaatttca atcccaatca agtaagaaaa
      961 ttgagtaaaa actcgatttg agagaaagtc caataagtct ttccataaca aaacgcatag
     1021 taacaagagt ttctacaccc actattatac gtttttatca ttttgaaatc tgctgctaat
     1081 caatgaagaa gcaaagatca aactaggcag ctagttacaa gttacgtaag cgcgtcataa
     1141 caaggtatct atcctaattc cccaacttcc agtatactag ataaaaaata attatcagag
     1201 gaaaggtatt gtactatgat gattgtacta agtgatttag gtcaagttca ccttgtttgt
     1261 ggcaagacag atatgaggca gggaatagac tcattagcct atgtagttaa aacccacttt
     1321 gaattggatc ctttctccgg tcaagtcttt ctcttttgtg gtggacgtaa agaccgcttt
     1381 aaagcccttt actgggatgg tcaaggattt tggctactat ataaacgctt tgagaacggc
     1441 agactgactt ggcccagtac agaaaaggat gtcaaagctc tcacatctga acaagtagac
     1501 tggcttatga agggcttttc tatcactccc caaatatagt gg
//
LOCUS       DAVBCA010000112         1455 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.112, whole genome shotgun sequence.
ACCESSION   DAVBCA010000112 DAVBCA010000000
VERSION     DAVBCA010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1455)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1455)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1455
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.112"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(412..804)
                     /gene="rpsI"
                     /locus_tag="VQU19_002077"
     CDS             complement(412..804)
                     /gene="rpsI"
                     /locus_tag="VQU19_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HET2481255.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(824..1270)
                     /gene="rplM"
                     /locus_tag="VQU19_002078"
     CDS             complement(824..1270)
                     /gene="rplM"
                     /locus_tag="VQU19_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HET2481256.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
BASE COUNT          420 a          290 c          279 g          466 t
ORIGIN      
        1 cccaaactct tcacacaaga gttctaactt acccattcta tggaatcttg cattatccat
       61 aatatagtag attgaaacta gaatagtaca cctctacttc taaaacattg ttagaattcg
      121 atttgactat cctcggtttg tcctattctt atttcacctt actataaaaa taaggtaaac
      181 ttttcaaaaa aacacgaaaa aagcacccat agggcaaacc tttgagtgct ttgaaacatt
      241 gatataattg tattgattag cgttttgagg caactgacct tgtcaggttg cagccacatt
      301 tgtaagcaac taaagtcgca acaactgtgt caattgcacc aatttagtaa gaaagtataa
      361 aaaaagaaca ccccgaaagg tgctctgtat aagtatagta attctttcga attaacgttt
      421 actaaattgt gatgctttac gagctttctt aagacctggt ttcttacgtt caactttacg
      481 tgagtcacgt gtaagaagtc ctgcgcgttt caatgaatcg cggaagtctg ggtctacttg
      541 aagaagggca cgagcgatac cgtgacggat agctcctgat tgaccagcgt atccaccacc
      601 tacaacgtta acgaaaacgt cgtatgaacc tacagttgaa gtaactgcga atggttggtt
      661 gatgacaaga cgaaggtcag catgtgggat gtactcttca acatcttttt tgttaacagt
      721 gattttacca gttcctggaa caaggcgaac gcgtgcaaca gcgtttttac gacgtccagt
      781 acctgcatat tgtgcttgtg acatacttta tttgttcctt tccttagata agtcctgaaa
      841 tgtcaagaac ttctggttgt tgtgcagcat gagtgtgctc agctccaaca aatactttca
      901 acttcatacc ttgagcgcgt ccaagtgtat tgtgtggaag cataccttta actgatttct
      961 caatcaaacg tactgcattt ttagaacgaa gttcacctgc agagatttgt ttcaatccac
     1021 ctgggtggtt tgagtgagtg tagtagattt tatcagttgc ttttttacca gtcaatttaa
     1081 ctttttcagc attgataaca atcacgaagt cacctgtatc agtgtgtggt gtaaatgttg
     1141 gtttgttttt tccgcgaagt acgctagcaa ctactgcaga aagacgtcca agtggtacat
     1201 cagttgcgtc aactacgtac catttacgtt caacttggcc tggtttagcc ataaatgttg
     1261 ttttgttcat gatttctcct atatatagtt cgatttttgt ttacggtgat gggtgttcct
     1321 tcccatcgaa aagtatttgg aaggttccgg ggcctttcaa atggggtaaa caataccgcc
     1381 tactatcata ccaaatttca cccctaaaag tcaatagata tgaaaaatat ttttcggtaa
     1441 cttctcaaag taact
//
LOCUS       DAVBCA010000113         1379 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.113, whole genome shotgun sequence.
ACCESSION   DAVBCA010000113 DAVBCA010000000
VERSION     DAVBCA010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1379)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1379)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1379
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.113"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..>1379
                     /locus_tag="VQU19_002079"
     CDS             <1..>1379
                     /locus_tag="VQU19_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET2481257.1"
                     /translation="EQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISEELLMKDPNY
                     QLKDEDIISEIKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHSQHREGGTS
                     TNDGAVAFARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKNELSASELA
                     AAEAFLSGRGNLSNSRTYRRQNSDNTSRTNWLPSVSNPGTTNTNTSNNSNTNSQASQS
                     NDIDSLLKQLYKLPLSQRHVESDGLVFDPAQITSRTARGVAVPHGNHYHFIPYEQMSE
                     LEKRIARIIPLRYRSNHWVPDSRPEQPSPQSTPEPSPSLQPAPNPQPAPSNPIDEKLV
                     KEAVRKVGDGYVFEENGVSRYIPAKDLSAETAAGIDSKLAKQESLSHKLGAKKTDLPS
                     SDREFYNKTYDLLARIHQDLLDNKGRQVDFEALDNLLERLKDVSSDKVKLVDDILAFL
                     APIRHPERLG"
BASE COUNT          454 a          296 c          282 g          347 t
ORIGIN      
        1 gaacaaatcg tcatcaagat aacagaccaa ggctatgtca cttcacatgg ggaccactat
       61 cattattaca atggtaaggt tccttatgac gctatcatca gtgaagaatt gctgatgaag
      121 gatccaaact accagctaaa ggacgaggat attatcagtg aaatcaaggg tggttatgtg
      181 attaaggtag atggaaaata ctatgtttac cttaaggatg cagctcatgc ggataatgtc
      241 cgtacaaaag aagaaatcaa tcggcaaaaa caagaacata gtcagcatcg tgaaggaggg
      301 acttcaacaa acgatggtgc ggtagccttt gcacgttcac aaggacgcta tactacagat
      361 gatggttata tctttaatgc ttctgatatc attgaggaca cgggtgatgc ttatatcgtt
      421 cctcacggcg accattacca ttacattcct aagaatgagt tatcagctag cgagttagct
      481 gctgcagaag ccttcctatc tggtcgggga aatctgtcaa attcaagaac ctatcgccga
      541 caaaatagcg ataacacttc aagaacaaac tggctacctt ctgtaagcaa tccaggaact
      601 acaaatacta acacaagcaa caacagcaac actaacagtc aagcaagtca aagtaatgac
      661 attgatagtc tcttgaaaca gctctacaaa ctgcctttga gtcaacgcca tgtagaatct
      721 gatggccttg ttttcgaccc agcgcaaatc acaagtcgaa ccgccagagg tgtagctgtc
      781 cctcatggta accattacca ctttatccct tatgaacaaa tgtctgaatt ggaaaaacga
      841 attgctcgta ttattcccct tcgttatcgt tcaaaccatt gggtaccaga ttcaagacca
      901 gaacaaccaa gtccacaatc gactccggaa cctagtccaa gtctgcaacc tgcaccaaat
      961 cctcaaccag ctccaagcaa tccaattgat gagaaattgg tcaaagaagc tgttcgaaaa
     1021 gtaggcgatg gttatgtctt tgaggagaat ggagtttctc gttatatccc agccaaggat
     1081 ctttcagcag aaacagcagc aggcattgat agcaaactgg ccaagcagga aagtttatcg
     1141 cataagctag gagctaagaa aactgacctc ccatctagtg atagagaatt ttacaataag
     1201 acttatgact tactagcaag aattcaccaa gatttacttg ataataaagg tcgacaagtt
     1261 gattttgagg ctttggataa cctgttggaa cgactcaagg atgtctcaag tgataaagtc
     1321 aagttagtgg atgatattct tgccttctta gctccgattc gtcatccaga acgtttagg
//
LOCUS       DAVBCA010000114         1373 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.114, whole genome shotgun sequence.
ACCESSION   DAVBCA010000114 DAVBCA010000000
VERSION     DAVBCA010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1373)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1373)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1373
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.114"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(57..176)
                     /locus_tag="VQU19_002080"
     CDS             complement(57..176)
                     /locus_tag="VQU19_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HET2481258.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTL"
     gene            complement(280..429)
                     /gene="blpO"
                     /locus_tag="VQU19_002081"
     CDS             complement(280..429)
                     /gene="blpO"
                     /locus_tag="VQU19_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HET2481259.1"
                     /translation="MDTKMMSQFAVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
     gene            complement(673..876)
                     /gene="blpN"
                     /locus_tag="VQU19_002082"
     CDS             complement(673..876)
                     /gene="blpN"
                     /locus_tag="VQU19_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpN"
                     /protein_id="HET2481260.1"
                     /translation="MNTYCNINETMLSEVYGGNSGGAAVVAALGCAAGGVKYGRLLGP
                     WGAAIGGIGGAVVCGYLAYTATS"
     gene            complement(892..1146)
                     /gene="blpM"
                     /locus_tag="VQU19_002083"
     CDS             complement(892..1146)
                     /gene="blpM"
                     /locus_tag="VQU19_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpM"
                     /protein_id="HET2481261.1"
                     /translation="MDTKIMEQFHEMDITMLSSIEGGKNNWQTNVLEGGGAAFGGWGL
                     GTAICAASGVGAPFMGACGYIGAKFGVDLWAGVTGATGGF"
BASE COUNT          462 a          315 c          166 g          430 t
ORIGIN      
        1 attaaagaaa ctcccctgta aattaagcta gcaaatacag gggagaaatt tattttttag
       61 agagtactat ccgtatcctt tttggaagat tttgaaaata tttttctaat taagtcatcc
      121 atataaggac caaatatacc aactactaaa ccaataataa aacttttaaa atccataatt
      181 accaccaaca tattgctgca taggctacac ctccaagtat agctccacct gcagcaccag
      241 ttacacctat tcctatagca aatggtccca atagaaatgt caaaccgttg ttgcacaccc
      301 atcaattgcg ccatatgcaa cccctgctgc acaactaatt tttcttcccc aatcaatatc
      361 tccaccttca acgcaagcaa gcatttcatt atccataact gcaaattgtg acatcatttt
      421 tgtatccata tagtatatca cttttcagtt acggaacaag tttaatataa aaattatcaa
      481 aaaaacatag gcaataaaga gaaaaattaa tttatcatag attagaaata atatgacaaa
      541 acaattcaat gatgttaatt caatagtctt ttgtttttta tcggagatac ttatggatag
      601 ataaataaga taggtttgaa aagcgaagag aataataaag aatatagcct tcataaaatt
      661 tagctttcat ttttatgatg tagcggtata ggctaaatat ccacaaacca ctgctcctcc
      721 aattcctcct attgcagcgc cccatggtcc tagaagtctc ccatatttca ctccacccgc
      781 tgcacaacct aaagcagcaa ctacagctgc tcctccggaa ttacctccat aaacctcact
      841 cagcattgtt tcatttatat tacaataagt attcatacaa gtctcctttt attaaaatcc
      901 acccgttgcc cctgttactc ctgcccaaag atccacacca aatttagctc ctatgtatcc
      961 acatgctccc ataaatggtg ctccaacacc actcgcagca caaatagctg tccctagccc
     1021 ccagccacca aaagcagcac caccaccttc caagacatta gtttgccaat tattcttgcc
     1081 tccttcaata ctagataaca tagttatatc catttcatga aattgttcca taatttttgt
     1141 atccatgaca aatactcttt tttattttta atttttgtct tgttgtaact ttgacaagtt
     1201 tagtatatca tcgtttttta aaatttttca tccagatctt gaatagtcat cgaaacgtct
     1261 tgaattgcaa aaattacatt agacttcctg caaaactaga atcctagttc atgattgata
     1321 ataccagcac tcaaattcat tcgtaatccg aagcgtttac gatgatttcg ata
//
LOCUS       DAVBCA010000115         1255 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.115, whole genome shotgun sequence.
ACCESSION   DAVBCA010000115 DAVBCA010000000
VERSION     DAVBCA010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1255)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1255)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1255
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.115"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(704..1255)
                     /locus_tag="VQU19_002084"
                     /pseudo
     CDS             complement(704..1255)
                     /locus_tag="VQU19_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          341 a          261 c          253 g          400 t
ORIGIN      
        1 tacgtgacag agtccagttc tatcagaccg ttcgttttac agacacaagt gaagtaggat
       61 tacttcgatt agttgtttac cccttcgctc cacttccatt acagaagttt cctcactact
      121 atgggctcgg ctgacttctc atgattcgtt gttactacgc tttcggcgct catgagacct
      181 cacgggataa gccgtacatc tttcctcgtt tatacaagat atgaggacgt taaaaggtta
      241 caatgaaaat aggaaatctg acgcagagtc tttagactct aggaagattt atctttttca
      301 catagacctt agtccgaatt caattactct cgtgatttac gcatataggt tacgactacc
      361 tttttggact ttagagtttt aagccccctt atccgctgta tacgccttac tatcacgttc
      421 ctgttcgtag agcctcgatt tcgctatccc ttcctctgac gattcttatt tcctgcgtca
      481 gacttaaaac ggtctatccc cagaccgttt taatccgcta cctcacgata gtcaggcttg
      541 ggaatcgcta ttgggttcac cggtagcagg tgcccacgga ggacttacac ctcagatgca
      601 cgacatgccc gtcgtactta aaatcagcct aaatgattca ggctgatttt tctattgatt
      661 caaaaaaacg gctctttgtc aactgtagtg ggttgaagaa aagctaagat cgagaaagga
      721 caaatttcgt cctttctttt ttgatattca gagcgataaa aatccgtttt ttgaagtttt
      781 caaagttccg aaaaccaaag gcattgtgct tgataagttt gatgagatta ttggtcgctt
      841 ccaatttggc gtttgaatag ggtagttgaa gggcgttgat aatcttttct ttatctttga
      901 ggaaggtttt aaagacagtc tgaaaaatag gatgaacctg cttcagattg tcctcaataa
      961 gtccgaaaaa tttctctggt tccttattct ggaagtgaaa aagcaagagc tgatagagct
     1021 gatagtggtg tttcaagtct tccgaatagc tcaaaagctt gtctaaaatc tctttattgg
     1081 ttaaatgcat acgaaaagta ggacgataaa aacgcttatc actcagttta cggctatcct
     1141 gttgtatgag cttccagtag cgcttgatag ccttgtattc atgggatttt cgatgaaact
     1201 gattcatgat ttaaacacgc acacgactca tagcacggct aagatgttgc acaat
//
LOCUS       DAVBCA010000116         1190 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.116, whole genome shotgun sequence.
ACCESSION   DAVBCA010000116 DAVBCA010000000
VERSION     DAVBCA010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1190)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1190)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1190
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.116"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            239..>1190
                     /locus_tag="VQU19_002085"
     CDS             239..>1190
                     /locus_tag="VQU19_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HET2481262.1"
                     /translation="MQEHYTPKGKHLTIDNRRLIERWKNENKSNREIAGLLGKAPQTI
                     HNEVKRGTTLQQVRKGLYKKVYSADYAQTVYQFNRKRSVKKLILTKEIREKILHYHKQ
                     KFSPEMMVNKKQVKVGISTIYYWFHNGHLGLTKADMLYPRKRKGVKKQASPNFKPAGK
                     SIEERPDVINLRLENGHYEIDTVLLTKIKNYCLLVLTDRRSRHQIIRLIPNKTAESVN
                     QALTLLLGEHRILSITADNGSEFKRLSEVFPEEHIYYAHAYSSWERGSNENHNRLIRR
                     WLPKGTKKTTPKEVAFIENWINNYPKKCLDYKSPSEFLLGG"
BASE COUNT          413 a          210 c          249 g          318 t
ORIGIN      
        1 agccacctta ccttagtcaa gaattagatg tttcactatg tttgagtaag ttgatgattt
       61 catttgataa caggtttgaa actgttaggc taggtggcca aggctaatca tagccttggt
      121 ttagctgaaa aaacaggttc aagggttcct gttgtcaaat gaaatgtgat ttaaggtata
      181 agaaaacacc tctgtgctat acttgttgtt caccacaaac acaaggaaag gcacagagat
      241 gcaagaacat tataccccaa aagggaaaca tttgacaata gataaccgtc gcttgattga
      301 gcggtggaag aatgaaaata agtccaatcg tgaaattgca ggcttgttag gaaaggcgcc
      361 tcaaacgatt cataatgaag tcaaaagagg tacaacttta caacaagtga gaaaagggct
      421 atacaaaaag gtctattctg ccgattacgc acaaactgtt taccaattca atcgaaaacg
      481 gtcggtgaaa aagttaattt taacaaagga aatcagagag aagatcttac actatcataa
      541 gcaaaaattt tcgcctgaaa tgatggttaa caagaagcaa gtgaaagttg gtatttcaac
      601 catctactac tggtttcata atggtcattt aggattgacg aaggccgaca tgctttatcc
      661 cagaaaaagg aaaggtgtca agaagcaagc tagtccgaac tttaagccgg caggtaaatc
      721 tatcgaagaa cgtcctgacg ttattaatct tcgcttggaa aatggtcatt atgaaattga
      781 taccgtccta ctgactaaga taaaaaatta ttgcctgtta gtcttaaccg accggcggag
      841 cagacaccaa attataaggt taattccaaa taaaactgct gaatctgtca atcaggcgct
      901 tacgttacta ttaggggagc atcgtattct gtccattact gcagataatg gttcggagtt
      961 caaacgattg tctgaggtat ttcctgagga acatatctac tacgcacatg cttactcttc
     1021 atgggagaga ggttcaaatg aaaatcataa tcgattaatt cggagatggt tacctaaagg
     1081 aaccaagaaa acgactccga aagaagtagc ttttatcgaa aattggatta acaactaccc
     1141 taaaaaatgc ttggactaca agtcgccaag tgaatttctt ttgggtggct
//
LOCUS       DAVBCA010000117         1142 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.117, whole genome shotgun sequence.
ACCESSION   DAVBCA010000117 DAVBCA010000000
VERSION     DAVBCA010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1142)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1142)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1142
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.117"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..1122
                     /gene="rlmD"
                     /locus_tag="VQU19_002086"
     CDS             <1..1122
                     /gene="rlmD"
                     /locus_tag="VQU19_002086"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HET2481263.1"
                     /translation="CGGCQIMHLHYDKQLEFKTDLLHQALKKFAPAGYENYEIRPTIG
                     MQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELKDCLVQDKETQVIANRLAELL
                     TYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNRQLNLTQLVKELVKDFPEVVT
                     VAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSLSPRAFYQLNPEQTEVLYSEA
                     VKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDIIPEAIEDAKRNAKRMGFDNT
                     HYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLLDTILTYVPEKMVYISCNVST
                     LARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKKV"
BASE COUNT          387 a          196 c          243 g          316 t
ORIGIN      
        1 tgcggaggct gccaaatcat gcacctgcat tatgataagc agctggagtt caagacggac
       61 ttacttcatc aagcgctgaa aaaatttgct cctgcaggat atgaaaatta tgaaattcgt
      121 ccaactattg gaatgcagga accaaaatat tacagagcta agttacaatt tcagactcga
      181 aaatttaaaa atcaggtcaa ggcgggctta tatgcacaaa actctcacta tttagtagag
      241 ttgaaagact gcctggtaca agataaggaa acccaagtga ttgctaatcg cttagcagaa
      301 ttacttactt atcaccagat tccaatcacg gatgagagaa aagttctagg tgtccgtact
      361 attatggtcc gacgcgcgag aaagaccgga caggttcaga ttattattgt tacaaaccgc
      421 cagcttaatt taactcaatt ggtaaaagag ttggttaaag atttcccaga agttgtgaca
      481 gtagctgtta atacaaatac agctaaaacc agtgagatat atggtgaaaa gacagagatt
      541 atctgggggc aagagagtat tcaagaaggt gtactcaatt atgaattttc actatcccct
      601 cgagcttttt atcaactaaa tcctgagcaa acagaagtcc tctatagcga agcagtaaaa
      661 gcgctggatg ttgataaaga agaccatttg attgacgctt attgtggagt tggaacgatt
      721 ggatttgcct ttgcaaagaa agtaaaaaca ctcagaggta tggatattat tccagaagct
      781 attgaagatg ccaagcgaaa tgctaaaaga atgggatttg acaatactca ttatgaagct
      841 ggaacggcag aagagattat tcctcgttgg tacaaggaag gctaccgagc agatgctttg
      901 attgttgacc caccacgtac aggtctggat gataagttat tagatactat tcttacttat
      961 gtaccagaaa aaatggttta tatttcttgt aatgtttcga ccttggctcg tgatttggta
     1021 cgcttagtag aagtctatga tcttcattat atccagtcgg tcgatatgtt cccacataca
     1081 gctcgaactg aagctgttgt aaaattaata aaaaaagttt aaaaaaggtg ttgacaaaac
     1141 at
//
LOCUS       DAVBCA010000118         1122 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.118, whole genome shotgun sequence.
ACCESSION   DAVBCA010000118 DAVBCA010000000
VERSION     DAVBCA010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1122)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1122)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1122
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.118"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(1..459)
                     /locus_tag="VQU19_002087"
                     /pseudo
     CDS             complement(1..459)
                     /locus_tag="VQU19_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
     gene            complement(695..1006)
                     /locus_tag="VQU19_002088"
     CDS             complement(695..1006)
                     /locus_tag="VQU19_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2481264.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYVCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCPFCFSRFNPGCQNHKERYF
                     K"
BASE COUNT          348 a          236 c          186 g          352 t
ORIGIN      
        1 cgcatcatca taagaaacca cttcagcgac aaacttgtac tcagggattt tacgacgagc
       61 accaaacaac tgctcatttt cagatggtgt accatagtaa aatcctgtag ccagttcacg
      121 ttgggcaacc ttccacatct cgtccaccaa gtcttgtttg atagcttcaa acttttcagg
      181 actttcaaga taggcatcca caaccgcctt gtagcagttg gttactgtta atacatagtg
      241 aatagactcc atacgtcctt cgatttttag actgtccaca ccattttcaa tcatatctgg
      301 aatgtggtca atcatagaca tgtcaacggc tgacattgaa aattcttctg gaatctcacc
      361 ctgcaaactc ttacgttctt tcccaaatgg catatcgtaa aggtcgtatt tccaacggca
      421 tgactgagaa catccaccac ggttggcatc acgcatactc tagacgcaat tctaatcttt
      481 tagactttgc ataataactg ttaaacagtt gaaaattaac ccagttttaa caagtagtca
      541 aaataccaga taaaggaaaa aaagtcttta aaatcttaaa aacgcatagt atcaggtatt
      601 gaacaatctt gatattatgc gttttattgt gggaagattt acttcatttt ctcttggaat
      661 tgagttttct cctacttcaa aactagatga tttgctattt aaaatagcgt tccttatgat
      721 tttggcaacc tggattaaag cgagaaaaac aaaaggggca acttaagctt tctttatatt
      781 gcttatatgt tagtagtttt agacaaacac cacataaaat aggcttatcc tgtatcaaag
      841 ataagggata cggctcaaaa gggtgatttt ctaatgaatc atgacaccga taacaagcat
      901 agtacttttt acaaacatag cattgtaaag caataatatc cagcttgcta tggtaatgaa
      961 tgcatcttgt ttgcttatcc actaagaaac cctgtgcctc tatcatttcc ttttcctttc
     1021 ttaagctcga actgtgacgc tggttccatc ttccttataa agattgatga gtccttcttt
     1081 taatgcacga accatgtctc cagcttgaac aggttgaggc ac
//
LOCUS       DAVBCA010000119         1070 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.119, whole genome shotgun sequence.
ACCESSION   DAVBCA010000119 DAVBCA010000000
VERSION     DAVBCA010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1070)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1070)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1070
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.119"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(1..78)
                     /locus_tag="VQU19_002089"
                     /pseudo
     CDS             complement(1..78)
                     /locus_tag="VQU19_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(527..925)
                     /locus_tag="VQU19_002090"
     CDS             complement(527..925)
                     /locus_tag="VQU19_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2481265.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
BASE COUNT          328 a          201 c          160 g          381 t
ORIGIN      
        1 acgcttgatt tcagtgtgga tagtttgagg agcttttcca agtagagagg caatttctct
       61 atttgatttc cctttgttcg ccttttgtag tataatggtt ttgcatctct gtgcctttct
      121 tgtgtttgtg gttgaacaac aagtataaca caaaggtgtt ttcttatgcc tacaagagct
      181 ttcattattt ccattttctt ttggatttca ctctattctg aaaaacttgt gtatatttac
      241 tgaagctagc aagtcttacc tgtaaattta atgaaagcaa cacaaaatcc gagaggggaa
      301 tctcggatta atgtcaattt aaaaagatag agagttttta gtttaaataa attgttttaa
      361 aatatcaaca acatcacttc ttttcttaac ctgataagcc ttgattccta attttggggc
      421 tacgattata ttgtcctcaa tatcgtctag aaagacacaa tttctaggtt ataactggta
      481 tttatcgata gttactcata tatatcagtc cacctccata ctcaccttac agattctttt
      541 gataataata tctttgccta atgtagagat agtcttgcaa agaaaaaact tccttgtagc
      601 catgtttctg ataaaagtcc ggtgcctgga actggtaagt attgacaaag gcaaaacaac
      661 aatttcgatt cttagcttca ctttctgcct gttgcaatag ttttgaaccg attccttgcc
      721 ctcgcagttc ctcttttaca aacaaatact cgatttctag ccaatttcca aaagtctctg
      781 ctatcaaacc cgcaaggaga ttgccctttt catcttcgac ataaagatta agtggctcac
      841 tttcagcctc ttctcttttt gaacggttat aaacacgaat cagattccct atttcttgcg
      901 atttatgtga ttccttattt tccaatctaa agtataatga aatgaaataa aacatgcgca
      961 aatcgattaa ggaatttaat ctaatttcta acaatgtctt agaaatcaaa gtgtactatt
     1021 ttaacttcaa tgcactatac atctaatact caataaaaat caaagagcaa
//
LOCUS       DAVBCA010000120         1054 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.120, whole genome shotgun sequence.
ACCESSION   DAVBCA010000120 DAVBCA010000000
VERSION     DAVBCA010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1054)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1054)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1054
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.120"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..555
                     /locus_tag="VQU19_002091"
     CDS             <1..555
                     /locus_tag="VQU19_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET2481266.1"
                     /translation="KDETTSYPIYEIPEAWRYIKFASLVNFRIGKTPPRSEATFWGTE
                     IPWVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTLLMSFKLSIGKVAILDIPA
                     THNEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAIKGKTLNSTSISELLIPIS
                     NHEEMKRIISKVDLLFQKVSQLFE"
     gene            complement(503..1048)
                     /locus_tag="VQU19_002092"
     CDS             complement(503..1048)
                     /locus_tag="VQU19_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001104691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET2481267.1"
                     /translation="MNWVVIKIKDIFSINTGLSYKKGDLSINNKGVRIIRGGNIKPLE
                     FSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHIGKFARIDKDYDGVVAGGFIF
                     QLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQALYNIPKTTLSELLIPLAPFE
                     EQELITQKVEKLFEKVNQLWK"
BASE COUNT          380 a          165 c          153 g          356 t
ORIGIN      
        1 aaagacgaaa caacctctta tcctatatat gaaatcccag aagcatggag atatattaaa
       61 tttgctagcc tagttaactt cagaatagga aaaactcctc cacgcagtga agctactttt
      121 tggggaactg aaataccttg ggtatctata tcagatatgc ctatatctgg ttatgtaact
      181 aatacgagag aatctatttc taaattagca ttaaaatcaa agaaaataga catttcacct
      241 aaaggaactt tattaatgag ttttaaatta tctattggaa aagttgccat attggatatt
      301 cctgccactc ataatgaagc cattatatcg atattcccct atgctaataa agaaaatatt
      361 atcagagatt acttaatgat atttttgcca cttatctcta ctttaggtga ttcaaaagat
      421 gctataaaag ggaaaacatt aaatagtacc agtatctccg aattattaat ccctatttct
      481 aatcatgaag agatgaaaag aatcatttcc aaagttgatt tactttttca aaaagtttct
      541 caactttttg agtaataagt tcctgttcct caaaaggagc taacggaatt aatagctcgc
      601 ttagtgtagt tttaggaata ttatataaag cttgacctga tagtttagtt attgctttca
      661 attgtttata aaataacgga gaggacaagt taaataatag aaattttgaa ataatctctg
      721 aactttcgaa tggtgttaat tggaaaataa atccaccagc cacaacacca tcatagtctt
      781 tatcgattct tgcaaacttt ccaatatgtt ctaaagaggt tgatacaggt gttattagct
      841 gattatgttt taaataaact tgctcagagg agatgaattg tgtatcaatg tagtaatcat
      901 tatccaacag agaaaattct aaaggcttaa tattaccacc acgtataatt ctaacacctt
      961 tattattaat gcttaaatcg cccttcttgt aagaaagacc tgtatttatt gaaaaaatat
     1021 cttttatttt tataacaacc caattcatag gtat
//
LOCUS       DAVBCA010000121         1035 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.121, whole genome shotgun sequence.
ACCESSION   DAVBCA010000121 DAVBCA010000000
VERSION     DAVBCA010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1035
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.121"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..990)
                     /gene="ltrA"
                     /locus_tag="VQU19_002093"
     CDS             complement(<1..990)
                     /gene="ltrA"
                     /locus_tag="VQU19_002093"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HET2481268.1"
                     /translation="MSKLLDKILSRDNMLEAYNQVKSNKGSAGIDGITIEEMDGYLRQ
                     NWRLTKELIKQRKYKPQPVLRVEIPKPNGGIRQLGIPTVMDRMIQQAIVQVISPICEP
                     HFSDTSYGFRPNRSCEKAIMKLLEYLNDGYEWIVDIDLEKFFDTVPQDRLMSLVHNII
                     EDGDTESLIRKYLHSGVIINGQRYKTLVGTPQGGNLSPLLSNIMLNELDKELEKRGLR
                     FVRYADDCVITVGSEAAAKRVMYSVSRFIEKRLGLKVNMTKTKITRPRELKYLGFGFW
                     KSSDGWKSRPHQDSVWRFKLKLKKLTQRKWSIDLTRRIEQLNLSIRGWINYFSL"
BASE COUNT          270 a          226 c          183 g          356 t
ORIGIN      
        1 caatgagaaa tagtttatcc atcctcgaat agacaaattc agttgctcaa tacgtcttgt
       61 taggtctata ctccatttcc tctgtgttag tttcttcaat ttaagcttaa atctccaaac
      121 actatcttga tgtggacgac ttttccaacc atctgatgat ttccagaacc cgaaacctag
      181 atatttcaac tctcttggtc tggtaatctt agtcttggtc atgtttactt tcagacctag
      241 ccgtttctca ataaaacgac tgactgaata catcacacgc ttagcggctg cctcgcttcc
      301 gaccgtaatc acacaatcgt ctgcgtagcg aacaaatcga agccctctct tttctaattc
      361 cttgtccaat tcattaagca tgatattgga taagagagga gataaatttc ctccctgtgg
      421 cgtgccaact agcgttttat aacgttgacc gttaatgata acacctgaat gaagatattt
      481 acgaatcaag gattccgtat ctccgtcttc gataatgtta tgtactaagg acatcaatct
      541 atcttgagga actgtatcga aaaatttctc taggtctatg tccactatcc actcatagcc
      601 gtcatttaag tactctaaga gcttcatgat ggctttttca catgacctat ttggtctgaa
      661 tccatagctc gtatctgaga aatggggttc acaaataggg ctaataactt gaacaatggc
      721 ctgttgaatc attctatcca taactgttgg aattcctagt tggcggatgc ctccgtttgg
      781 tttgggaatc tcaactctaa gaactggttg aggcttatat tttctctgtt ttatcagttc
      841 cttagtcagg cgccagtttt gtctgagata gccatccatc tcttcgatag taattccatc
      901 aatcccagct gagcctttat tagattttac ttgattgtag gcttcaagca tattgtcgcg
      961 tgataatatt ttatctagca attttgacat gtgcctattc ctttcttgtt ttggtgcctg
     1021 agggacatct tatat
//
LOCUS       DAVBCA010000122          948 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.122, whole genome shotgun sequence.
ACCESSION   DAVBCA010000122 DAVBCA010000000
VERSION     DAVBCA010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 948)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 948)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..948
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.122"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..337)
                     /locus_tag="VQU19_002094"
     CDS             complement(<1..337)
                     /locus_tag="VQU19_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002202361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2481269.1"
                     /translation="MDSASIIAHTIHQKFNLKVPNYRQEEDWARMGLPITRKEIANWH
                     IKASQYYLESLYNLLREKLLEQPLLHADETSYRVLESDSQLTYYWTFLSGKSEKQGIT
                     LYHHDQCRSG"
     gene            complement(345..650)
                     /locus_tag="VQU19_002095"
     CDS             complement(345..650)
                     /locus_tag="VQU19_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase zinc-finger binding
                     domain-containing protein"
                     /protein_id="HET2481270.1"
                     /translation="MFPVETEEITYKRKKSKGKRQALLAQFDSEEVHHQVEESICSDC
                     QGDLKEIGATLQRQELVFIPAQLKRIDHIQHAYKCQACSDKNPSDKIVKAPIPKAPL"
     gene            complement(637..831)
                     /locus_tag="VQU19_002096"
     CDS             complement(637..831)
                     /locus_tag="VQU19_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2481271.1"
                     /translation="MKIIQQQSATIDSLTNALALLREQVAYLTQKLYGKSSEKSVCPS
                     GQLNLFEEESPSEKDGDVPS"
BASE COUNT          259 a          182 c          188 g          319 t
ORIGIN      
        1 aaccacttcg acactgatca tggtggtaaa gcgtaatccc ttgtttctct gatttacctg
       61 acaaaaaagt ccaatagtaa gtcagctgac tatcactttc taagacccga taagaggttt
      121 catctgcatg aagaagaggt tgttctaaca acttttctcg taaaaggtta taaagggact
      181 ctaaatagta ttgactcgcc ttgatatgcc aattagcaat ttccttacgt gtgattggta
      241 aacccatcct agcccaatct tcttcttggc gataattagg taccttcaga ttaaacttct
      301 gatggatggt gtgagcgata atagaagctg agtcaatagt ctcgttataa aggggcttta
      361 ggaataggag ctttcacaat tttatcactc ggatttttat cactgcatgc ttggcatttg
      421 taagcgtgtt ggatatgatc tatgcgtttt aattgcgcag gaataaagac taattcttgt
      481 cgttgaaggg ttgctccaat ctcttttaga tctccctgac aatcagagca aatgctctct
      541 tctacttgat gatgaacttc ttctgaatca aattgggcaa gaagagcttg gcgtttccct
      601 ttagatttct tacgtttgta ggtaatttcc tctgtttcaa ctgggaacat ctccatcttt
      661 ctcagatgga gactcttcct caaaaaggtt gagttgtcca gaggggcaaa cacttttctc
      721 agaggatttt ccatagagct tttgagtcag ataagccact tgttcacgaa gaagggcaag
      781 tgcattggtg agactatcaa ttgtagcact ctgttgttga atgattttca atcttcttcc
      841 atgggcttcc cctccttgtt ttctaccttt attatactaa aaagaaagtc ctcatttcaa
      901 tagaaatcac gactttctga tggatttatt tttggagtga tagaaaag
//
LOCUS       DAVBCA010000123          909 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.123, whole genome shotgun sequence.
ACCESSION   DAVBCA010000123 DAVBCA010000000
VERSION     DAVBCA010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 909)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 909)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..909
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.123"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            751..>909
                     /locus_tag="VQU19_002097"
     CDS             751..>909
                     /locus_tag="VQU19_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET2481272.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVATLLEEREIVTPTYREA
                     LITREKSFP"
BASE COUNT          310 a          147 c          166 g          286 t
ORIGIN      
        1 gcgccattaa atcattggtt atgggacgga gtaaaagagt ccagtggact cttttagcct
       61 gagctcagtt taaaaaagcg agggtggtta ttttctcaaa gttttgaagg agctaaagca
      121 agagctatta ttatgagctt gttggaaaca gctaaacgtc atcaattata gtgcgttgaa
      181 tctataacag tacgcatcga ctgctaaaac atttctataa atcaattttc ctttcctaat
      241 cgatttgttc atatcttatt tcaatccatt ataaatagcg agaaatatct atcctatctt
      301 ctagaatgtc ttccaaacga ggaaactctc gtaaacaaag aggttttaga ggcctattta
      361 ccatggacta aagttgtaca agaaaagtgc aaataagaaa tctccagatt aggaactatc
      421 cgtgagttca ctaatctgga gatttttcaa tagacttcgt tattgggcgg ttacgatatg
      481 atcactgact tcgtcagtct tatctacaac ctcaaaactg tgttttgagc aacctgcggc
      541 tagcttccta gtttgctctt tgattttcat tgagtattag aacagaaaaa atacttggag
      601 tatttgtttg tgtgtttatt tttatataac aaactataaa caaaacaaaa atataaaaaa
      661 agagacaaaa aagaacagaa agcaattgac aacggtttca tatagtgtta tacttatggc
      721 ataaagttaa tggaaagaag ggaaaaactt atggtattag attatttctt tgacaaaaac
      781 cttgtgtttt gcttagaagc ggataatcaa gaacaactct ttgatcaggt tgcaacttta
      841 ttggaagaac gagaaattgt cactccaact tatcgtgaag ccttgatcac gcgtgaaaag
      901 tcatttcca
//
LOCUS       DAVBCA010000124          902 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.124, whole genome shotgun sequence.
ACCESSION   DAVBCA010000124 DAVBCA010000000
VERSION     DAVBCA010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 902)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 902)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..902
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.124"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            122..590
                     /locus_tag="VQU19_002098"
                     /pseudo
     CDS             122..590
                     /locus_tag="VQU19_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817843.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          331 a          135 c          166 g          270 t
ORIGIN      
        1 gagaagagga ttgccatctt ctccattttt atgtgcagag ttatagtggc ttgatgctgg
       61 gaaagtacac tgtgactgct aaaacattcc tagaagctgc tttgatttcc ctaatctatt
      121 tatgcaaatt ttatgttatt ttactataac agttgttgct aagccaaata atagtgggga
      181 agttcattta gacgtaagca ttgaagataa tcagggaggt agtgggtata atttcagttc
      241 tgtttcaagt agctcacaaa cagctaaata tgaaggaact ggttataata acaattcatc
      301 attatatata acgattgata aaacgtctga tgcaacagct cttttgaaat taaagttgaa
      361 taatgttgat aatcaacctg ctactgaagt tcctagttca ggaattactg taaaattaaa
      421 tgctaaagat aatgctggaa actggacaag tgcttcgaat aaagacaagt gcttcgaata
      481 aaaaagaaat aacagtaaaa attgtttctg ctaaaccgac atatccagac aaaatcttag
      541 tgaaaaatcc tgataatata aaagatacag aaaaaaatgc cattattgaa aaattgaaag
      601 aggcaaataa aaatcatcca gcaggagctc caacctttgc taaaggtgaa ggagagcatg
      661 caaatgatat tgtagcaact tattcagatg gtacaactta ttatgtaccg ttaaatgatg
      721 tgacaaaata tgcgaggtag tggctgtacc actcacttat tcacctcccc gtgatttgta
      781 gtagtgatag gctttctcac tattattata aaacaaaata aagatcacaa cactttttca
      841 ttctgtgttg tgccttgagt gaaacgaaag gaatgaatta taaatatgaa aagtatagtc
      901 ac
//
LOCUS       DAVBCA010000125          870 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.125, whole genome shotgun sequence.
ACCESSION   DAVBCA010000125 DAVBCA010000000
VERSION     DAVBCA010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 870)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 870)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..870
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.125"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(1..229)
                     /locus_tag="VQU19_002099"
                     /pseudo
     CDS             complement(1..229)
                     /locus_tag="VQU19_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            498..870
                     /locus_tag="VQU19_002100"
                     /pseudo
     CDS             498..870
                     /locus_tag="VQU19_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
BASE COUNT          283 a          168 c          166 g          253 t
ORIGIN      
        1 cagtattaca tccaccagct attaagaaaa atgattcgcc tgtatgggca tcaacagctc
       61 cataacaata gtgaaattct cgtatatagt gactatggac atgtggacct actcctattg
      121 gagaccaaca agatcccagt ttactgattc taccgaagcc agcctcatct tggtacatca
      181 agcgaacctt atgaaaacgt ctactggttt taaagcgctt tcttttcttc agttgatttc
      241 atatcactat tgtataatgc tttttgattt tagtctagta taaatagcga gaaatatcta
      301 tcctatcttc tagaatgtct tccaaacgag gaaactctcg taaacaaaga ggttttagag
      361 gcctatttac cgtggactaa agttgcacaa gaaaagtgca aataagaaat ctccagatta
      421 ggaactatcc gtgagttctc tagtctggag atttttcaat agacttcctg cgaaacaaaa
      481 tatggtataa tagttctatg aattatgaag caagtaaaca actaaccgat gcacgattta
      541 agcgtcttgt tggtgttcaa cgcacgactt ttgaagagat gttagctgta ttaaaaacag
      601 cttatcaact taaacacgca aaaggtggac gaaaacctaa attaagccta gaagaccttc
      661 ttatggccac tcttcaatat gtgcgagaat atcgaactta tgaagaaatt gcggctgatc
      721 ttggtattca cgaaagcaac ttactccgtc ggagccaatg ggttgaagta actcttgttc
      781 aaaggtggtg ttgcgatttc aagaactcct ctcagttctg aggacacggt aatgattgat
      841 gcgacggaag taaaaatcaa tcgacctaaa
//
LOCUS       DAVBCA010000126          830 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.126, whole genome shotgun sequence.
ACCESSION   DAVBCA010000126 DAVBCA010000000
VERSION     DAVBCA010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 830)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 830)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..830
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.126"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            21..830
                     /locus_tag="VQU19_002101"
                     /pseudo
     CDS             21..830
                     /locus_tag="VQU19_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558050.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5-like element IS1515 family transposase"
BASE COUNT          266 a          174 c          162 g          228 t
ORIGIN      
        1 aaaagtgtta tactattttt atggaaacag tatacgacaa agcacaaaaa cttaactcaa
       61 aaaacttcaa actattgatt ggtgtcaaaa aggaaacctt tcaactcatg ctagaacacc
      121 tgaattcagc ctatcagatt cagcaccgaa aaggtggacg tccacgtagt ctgcccatgg
      181 aagaccagct cattatgacc ctccgttact tgcgatatta tcccactcag cgtctgctgg
      241 cctttgattt tggcgtcggt gtagctacgg taaatgccat catcacttgg gtggaggata
      301 cacttcgtgc gtcaggtagc tttgatttgg accatttaga agccccgagt gctgctgtgg
      361 ctattgacgt gaccgaaagt ccgattcagc gtccaaaaaa aaccaaagca aaaattattc
      421 tggtaaaaag aaacgacaca ccttaaaaac tcaaattatg ctggatttga cgacacataa
      481 agtctgtcaa atggcctttt ctgacggaca tacgcatgat tttactctct tcaaagaaag
      541 tattggacaa agtttgcctg aaacgacgct tgcctttgtt gacctaggtt atttaggcat
      601 cttgaaattt catgagaata ctttcattcc tgctaaaaat tccaaaaatc gccgcctgag
      661 tgaggatgat aagcagttaa ataaagagat gtcagcgata cgaattgaaa ttgaacattt
      721 taacgctaaa ttcaagacct tccaaatcat gtcagtccct tatcgtaacc gcagaaaacg
      781 tttcgagtta cgggcggaat taatttgtgc catcatcaat tatgaagtga
//
LOCUS       DAVBCA010000127          707 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.127, whole genome shotgun sequence.
ACCESSION   DAVBCA010000127 DAVBCA010000000
VERSION     DAVBCA010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 707)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 707)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..707
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.127"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..>707)
                     /locus_tag="VQU19_002102"
     CDS             complement(<1..>707)
                     /locus_tag="VQU19_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element IS1167A family transposase"
                     /protein_id="HET2481273.1"
                     /translation="HQLAISTSTVIRKLNDFHFEHDFSRLPKIMSWDEYAFTKGKMSF
                     IAQDFDNLNIITVLEGRTQAVIRNHFLRYDRAVRCQVKIITMDMFSPYYDLAKQLFPC
                     AKIVLDRFHIIQHLSRAMSRFRVQIMNQFERKSHEYKAIKRYWKLIQQDSRKLSDKRF
                     YRPTFRMHLTNKEILDKILSYSEDLKHHYQIYQLLLFHFQNKDPEKFFGLIEDNLKQV
                     HPLFQTVFKTFLKNKEK"
BASE COUNT          227 a          118 c          147 g          215 t
ORIGIN      
        1 attttctctt tgttctttag aaaggtttta aagacagtct gaaaaagagg atgaacctgc
       61 ttcagattgt cctcaatgag tccgaaaaat ttctcagggt ctttgttctg aaagtgaaaa
      121 agtaagagtt gatagatctg atagtggtgt ttcaagtctt ctgaatagct taaaatcttg
      181 tcaagaattt ctttatttgt taagtgcatg cgaaaagtag ggcgataaaa acgtttatcg
      241 ctcaatttac gactatcctg ttggatgagt ttccagtaac gcttgatagc cttgtattca
      301 tgagattttc gttcaaactg attcataatt tgaacacgaa aacgactcat ggcacggctg
      361 agatgttgga taatatggaa acgatctaga acgattttag cacacggaaa aagctgttta
      421 gccaagtcat agtaaggact aaacatatcc atcgtaatga ttttcacttg acaacgaacg
      481 gctctatcgt agcgaagaaa gtgatttcgg atgacagctt gtgttctgcc ttcaagaaca
      541 gtgataatat taagattatc aaaatcttgc gcaatgaaac tcatctttcc cttagtgaag
      601 gcatactcat cccaagacat aatctttgga agccgagaaa aatcatgctc aaagtgaaag
      661 tcattgagct tgcgaatgac agttgaagtt gaaatggcca gctgatg
//
LOCUS       DAVBCA010000128          650 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.128, whole genome shotgun sequence.
ACCESSION   DAVBCA010000128 DAVBCA010000000
VERSION     DAVBCA010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 650)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 650)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..650
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.128"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            101..265
                     /locus_tag="VQU19_002103"
     CDS             101..265
                     /locus_tag="VQU19_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2481274.1"
                     /translation="MKKKILIIFVLYLIMSIFLYPLRESAWYQLFYTIAYVIAVMIYF
                     AINKKKGEKK"
     gene            262..>650
                     /locus_tag="VQU19_002104"
     CDS             262..>650
                     /locus_tag="VQU19_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000846948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HET2481275.1"
                     /translation="MKTFFAKKRNIFLARLFLGQLPLLVSTYLFLSRQFLNFSVVFQF
                     LLVVINLASILVTVYLTREMRIREFEDDDLVSPRTNQLMFIGLTGFMSIICLYRGITA
                     GESYQQIIAYIGAVLCLIIMLLLMWGL"
BASE COUNT          184 a          103 c          119 g          244 t
ORIGIN      
        1 atttatgatt tgagtgatcc aaggtcaaaa taagtgctat actagcagtg taaatgttct
       61 tgctcaacta agataaatcg cacatttagg aggaaatctt atgaagaaaa aaatactgat
      121 tattttcgtt ctgtatctaa tcatgtccat ctttctatat ccgcttaggg agagtgcttg
      181 gtatcagcta ttttatacca tagcctatgt gattgcagtt atgatctatt ttgctatcaa
      241 taaaaagaaa ggagaaaaga aatgaaaact ttttttgcta aaaaacggaa catcttcctt
      301 gcgagattgt tcttaggtca gttgcccttg cttgtttcta cttatctatt tctatctcgt
      361 cagtttttaa atttttccgt agttttccaa tttcttttag tagttattaa cttggcttct
      421 attttggtta ctgtttatct cactagggaa atgaggataa gagagtttga agatgatgat
      481 ttggttagtc ctagaaccaa tcaacttatg ttcatcggct tgacaggttt tatgtctatt
      541 atttgtttgt atagaggtat cacagcagga gaatcctacc aacaaataat cgcttatatt
      601 ggcgctgttc tctgcttaat catcatgctt ctgctcatgt ggggcttgaa
//
LOCUS       DAVBCA010000129          611 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.129, whole genome shotgun sequence.
ACCESSION   DAVBCA010000129 DAVBCA010000000
VERSION     DAVBCA010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 611)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 611)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..611
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.129"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(189..>611)
                     /locus_tag="VQU19_002105"
     CDS             complement(189..>611)
                     /locus_tag="VQU19_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HET2481276.1"
                     /translation="KPNEEKPQTEKPEEDKEHDEVSEPTHPESDEKENHAGLNPSADN
                     LYKPSTDTEETEEEAEDTTDEAEIPQVEHSVINAKIAEAEALLEKVTDSSIRQNAVET
                     LTGLKSSLLLGTKDNNTISAEVDSLLALLKESQPTPIQ"
BASE COUNT          155 a          121 c           93 g          242 t
ORIGIN      
        1 gatgaagttt tttctcaact tcttttactt tattaaatag ttttctaaac cggttattta
       61 accatttaat taaccagtaa atagtttact atttaaaatt acttttgtca agtttctgtt
      121 acgtttttct aaaaaagaga agtaacacga aaggttactt ctccataaaa tatgctccat
      181 tcattttact actgtatagg agtcggttga ctttctttta acaaagccaa gagactatct
      241 acttctgctg aaatagtgtt attatctttc gttccgagaa gaagactact ttttagacca
      301 gtcaatgtct ccacagcatt ttgtctaata ctagaatctg ttactttttc tagcaaggcc
      361 tccgcctctg ctatcttagc gttaataaca gaatgctcta cttgaggaat ttcagcctca
      421 tctgtagtat cttcagcttc ttcctctgtc tcttccgtat cagtgcttgg tttataaaga
      481 ttatctgctg aaggatttaa accagcgtga ttctcttttt catcagattc agggtgagtt
      541 ggctcactta cttcatcatg ttccttatct tcctcaggtt tttctgtctg aggtttctcc
      601 tcgtttggtt t
//
LOCUS       DAVBCA010000130          607 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.130, whole genome shotgun sequence.
ACCESSION   DAVBCA010000130 DAVBCA010000000
VERSION     DAVBCA010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 607)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 607)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..607
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.130"
                     /strain="ST1"
                     /db_xref="taxon:1313"
BASE COUNT          188 a          109 c          159 g          151 t
ORIGIN      
        1 gcatgtcgta tatctgaggt gtaagtcctc ggtgggcacc tgctaccggt gaacccaata
       61 gcgattccca agcctgacta tcgtgaggta gcagggagag gaagggatag cgaaatcgtg
      121 gctctacgaa caggaacgtg atagtaaggc gtatatagcg gataaggagg cttcaaactc
      181 taaagtccaa aaaggtagtc gtaacctata tgtgtaaatc acgagagtaa ttgaattcgg
      241 actaaggttt gtgtgaaaaa gataaatctt tctagagtct aaagactctg cgtcagattt
      301 cctattttca ctgtaacctt ttaacgtcct catatcttgt ataaacgagg aaagatgtac
      361 gacttatccc gtgaggtttc atgagcgctg aaagcgtagt aacaacgaat catgagaagt
      421 cagccgagcc catagtagtg aggaaacttc cgtaatggaa gtggagcgaa ggggtgaata
      481 ctcaaacagt ctggggagag actgtttgag gtctgtcgct agaaagagaa aacgacagat
      541 cgaagtaatc ctacttcact tgtgtctgta aaatgagtgg tctgatagaa ctggactttg
      601 acacgta
//
LOCUS       DAVBCA010000131          569 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.131, whole genome shotgun sequence.
ACCESSION   DAVBCA010000131 DAVBCA010000000
VERSION     DAVBCA010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 569)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 569)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..569
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.131"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..>569)
                     /locus_tag="VQU19_002106"
     CDS             complement(<1..>569)
                     /locus_tag="VQU19_002106"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2481277.1"
                     /translation="AEALVDAEADALVEADSEAEVLAEADALVDAEADALVLAEADAL
                     VDAEADALVLAEAEALVDAEADALVLAEAEALVDAEADALVLAEADALVLAEAEALVD
                     AEAEALVDADSEALVDAEADALIDADSEADVLAEAEALVDAEAEALVDADSEALVDAE
                     AEADVDAEADALVDAEADALVDAEAEALV"
BASE COUNT          137 a          187 c          130 g          115 t
ORIGIN      
        1 tcaaccagcg cctcagcttc agcatcaacg agtgcgtcgg cttcagcatc aacgagtgca
       61 tcggcttcag catcaacgtc tgcctcagct tcagcgtcaa ccagtgcctc tgaatcggca
      121 tcaaccagtg cttcagcctc agcatcgaca agcgcttcgg cttcagcaag tacatcagct
      181 tctgaatctg catcaataag tgcgtcggct tcagcgtcaa ccagtgcctc tgaatcggca
      241 tcaaccagtg cttcagcctc agcatcaacg agtgcttcgg cttcagcaag tacaagtgcg
      301 tcagcttcag caagcacaag tgcgtcagct tcagcatcaa cgagcgcctc ggcttcagca
      361 agcaccagtg cgtcagcttc agcatcaacg agtgcctcgg cctcagcaag tacaagtgcg
      421 tcagcctcag catcaaccag tgcatcagcc tcagcaagta ccagtgcatc agcttccgca
      481 tcaacgagtg catcagcctc agcaagcacc tcagcttctg aatcggcctc aacgagtgcg
      541 tcagcctcag cgtcaacgag tgcttcggc
//
LOCUS       DAVBCA010000132          509 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.132, whole genome shotgun sequence.
ACCESSION   DAVBCA010000132 DAVBCA010000000
VERSION     DAVBCA010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 509)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 509)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..509
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.132"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..>509)
                     /locus_tag="VQU19_002107"
     CDS             complement(<1..>509)
                     /locus_tag="VQU19_002107"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2481278.1"
                     /translation="AEALVEADSDALVEADSDAEVLAEAEALVDAEAEALVLAEADAL
                     VLAEAEALVDADSDAEVLAEAEALVLAEADALVDAEAEALVDAEAEALVDADSEADVL
                     AEADALVDADSDALVDAEAEALVDADAEALVLAEADALVLAEAEALVDAEAEALVLAE
                     ADALVEAEA"
BASE COUNT          123 a          168 c          116 g          102 t
ORIGIN      
        1 tcagcttcgg cctcaacaag tgcgtcagct tcagcaagca ccagtgcttc ggcttcagcg
       61 tcgacaagtg cctcagcttc agcaagtacc agtgcgtcag cctcagcaag tactagcgcc
      121 tcagcatcag cgtcaacaag tgcttcggct tcagcgtcaa cgagtgcgtc tgagtcagca
      181 tcaacgagtg cgtcagcctc agcaagcaca tcagcttctg aatccgcatc aacaagtgct
      241 tcagcctcag cgtcaacaag tgcttcagct tcagcatcaa ccagtgcatc agcttcagca
      301 agtactagcg cctcagcttc agcaagcacc tcagcgtctg aatcggcatc aacgagcgcc
      361 tcagcttcag caagtaccag tgcgtcagcc tcagcaagta ccagtgcttc agcctcagcg
      421 tcgacaagtg cctcggcttc agcaagtacc tcagcgtctg aatcggcctc aaccagtgca
      481 tctgaatcgg cctcaaccag tgcctcagc
//
LOCUS       DAVBCA010000133          494 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.133, whole genome shotgun sequence.
ACCESSION   DAVBCA010000133 DAVBCA010000000
VERSION     DAVBCA010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..494
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.133"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(53..126)
                     /locus_tag="VQU19_002108"
     tRNA            complement(53..126)
                     /locus_tag="VQU19_002108"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(90..92),aa:Met,seq:cat)
     gene            complement(140..229)
                     /locus_tag="VQU19_002109"
     tRNA            complement(140..229)
                     /locus_tag="VQU19_002109"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(191..193),aa:Ser,seq:tga)
     gene            complement(312..385)
                     /locus_tag="VQU19_002110"
     tRNA            complement(312..385)
                     /locus_tag="VQU19_002110"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(349..351),aa:Ile,seq:gat)
     gene            complement(420..490)
                     /locus_tag="VQU19_002111"
     tRNA            complement(420..490)
                     /locus_tag="VQU19_002111"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(456..458),aa:Gly,seq:tcc)
BASE COUNT          141 a          137 c          109 g          107 t
ORIGIN      
        1 cgacacatgg agcttcaatc cattgctcta ccaactgagc taccgagcct tattgcggga
       61 gcaggatttg aacctacgac cttcgggtta tgagcccgac gagctaccga gctgctccat
      121 cccgcgttaa taatataaaa ggaggatgtg ggattcgaac ccacgcacgc ttttacacgc
      181 ctgacggttt tcaagaccgt tcccttcagc cggacttggg taatcctcca aaatagttta
      241 tacgggaaca agcccgtgtc ctcttagtga acagataata ttccaatccc ctagtaatgg
      301 actaaacact atgggcacga gtggactcga accaccgacc tcacgcttat caggcgtgcg
      361 ctctaaccac ctgagctacg cgcccaagtc aaaaacttgg tacaaagaac aaagttcaaa
      421 gcgggtgacg agaatcgaac tcgcgacaac agcttggaag gctgtagttt taccactaaa
      481 ctacacccgc taaa
//
LOCUS       DAVBCA010000134          489 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.134, whole genome shotgun sequence.
ACCESSION   DAVBCA010000134 DAVBCA010000000
VERSION     DAVBCA010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 489)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 489)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..489
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.134"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..>489
                     /locus_tag="VQU19_002112"
     CDS             <1..>489
                     /locus_tag="VQU19_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HET2481279.1"
                     /translation="KKDAHGIALKLLSDPNREQFQHDNRQVELKILARHIHRLKKKQS
                     DWKVQYTRCLDIIFPELDKIVEKHSEYTYQLLTCYPNPQKRLEAGFDKLIEIKRLTAS
                     KIQDILSVAPRSIGTTSPAREFEIIKHYKRLIDKAETCVNDLMAEFNSVITTVTGIGN
                     RL"
BASE COUNT          158 a          106 c           93 g          132 t
ORIGIN      
        1 ataagaaaga cgctcatggc atcgctctta aacttctttc tgaccccaat cgtgaacaat
       61 ttcaacacga taatcggcaa gtagaactaa aaatactggc tagacatatt catcgtctca
      121 agaaaaaaca gtctgattgg aaagtacaat acactcgttg tcttgatatc atctttcctg
      181 agttggataa aatcgttgaa aagcattcag aatataccta ccaactcttg acatgctacc
      241 ctaatcctca gaaaaggctt gaggcaggat ttgataagct gatagaaatt aagcgattga
      301 ccgcttctaa aattcaggat atcctctcag ttgcacctcg ttctatcgga acaacatctc
      361 ctgctcgtga attcgaaatc atcaaacatt acaagaggct cattgacaag gcggaaacat
      421 gtgtcaatga cttgatggct gagttcaact cggtcatcac gacggtcact gggattggga
      481 atcgtttag
//
LOCUS       DAVBCA010000135          482 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.135, whole genome shotgun sequence.
ACCESSION   DAVBCA010000135 DAVBCA010000000
VERSION     DAVBCA010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 482)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.135"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..>482)
                     /locus_tag="VQU19_002113"
     CDS             complement(<1..>482)
                     /locus_tag="VQU19_002113"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2481280.1"
                     /translation="EALVLAEADALVLAETEALVLAEAEALVDAEAEALVLAEAEALV
                     DADSDAEVLAEAEALVDAEAEALVLAEAEALVLADSDALVDAEAEALVDAEAEALVDA
                     EADALVDAEAEALVDAEAEALVDAEAEALVLAEADALVDAEAEALVLAEADALVEAEA
                     "
BASE COUNT          120 a          161 c          106 g           95 t
ORIGIN      
        1 tcagcttcgg cctcaacaag tgcgtcagct tcagcaagca ccagtgcttc ggcttcagcg
       61 tcgacaagtg cgtcagcctc agcaagcacc agtgcctcag cttcagcatc aacaagtgct
      121 tcagcctcag cgtcaacaag tgcttcagct tcagcatcaa caagtgcgtc agcttcagca
      181 tcaaccagtg cctcagcctc agcgtcgaca agtgcctcgg cttcagcatc gacaagtgca
      241 tctgaatcag caagcacaag tgcttcagct tcagcaagta ccagcgcctc agcctcagca
      301 tcaaccagtg cttcggcttc agcaagtacc tcagcgtctg aatcggcatc aacaagtgct
      361 tcagcttcag caagtacaag cgcctcagct tcagcatcaa ccagtgcttc ggcttcagca
      421 agcaccagtg cctcagtctc agcaagcacc agtgcgtcgg cttcagcaag cacaagcgcc
      481 tc
//
LOCUS       DAVBCA010000136          393 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.136, whole genome shotgun sequence.
ACCESSION   DAVBCA010000136 DAVBCA010000000
VERSION     DAVBCA010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 393)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 393)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..393
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.136"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..>393
                     /locus_tag="VQU19_002114"
     CDS             <1..>393
                     /locus_tag="VQU19_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HET2481281.1"
                     /translation="YLHLWELSDWDQEGMLCLHELISREEGLVDDIPRLRKYFKTKFR
                     NRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLWLDDYYLFHETLRDYRNKQSK
                     EKQEELERVLSNERFRGRQRVLRDLRIVF"
BASE COUNT          143 a           57 c           93 g          100 t
ORIGIN      
        1 taccttcatt tatgggaatt gtcggattgg gaccaagaag gcatgctctg cttacatgaa
       61 ttgattagta gagaagaagg actggtagac gatattccac gtttaaggaa atatttcaaa
      121 accaagtttc gaaatcgaat tttagactat atccgtaagc aggaaagtca gaagcgtaga
      181 tacgataaag aaccctatga agaagtggga gagatcagtc atcgtataag tgaggggggt
      241 ctctggctag atgattatta tctctttcat gaaacactaa gagattatag aaacaaacaa
      301 agtaaagaga aacaagaaga actagaacgc gtcttaagca atgaacgatt tcgagggcgt
      361 caaagagtat taagagactt acgcattgtg ttt
//
LOCUS       DAVBCA010000137          329 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.137, whole genome shotgun sequence.
ACCESSION   DAVBCA010000137 DAVBCA010000000
VERSION     DAVBCA010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 329)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 329)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..329
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.137"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(238..325)
                     /locus_tag="VQU19_002115"
     tRNA            complement(238..325)
                     /locus_tag="VQU19_002115"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(289..291),aa:Ser,seq:gct)
BASE COUNT          113 a           67 c           50 g           99 t
ORIGIN      
        1 gcaatgcctt tggttttcga aactttgaaa actttaaaaa acggattttt atcgctttga
       61 acatcaaaaa agaaaggacg aaatttgtcc tttctcgagc ttagcttttc ttcaacccac
      121 tacagttgac aaagagccat aaaaataact tcagattagt aattcaatta agttttacgg
      181 atctgaagct ttattgtctc taaaaataaa aaagagagtt acaaactctc attaaaacgg
      241 agaataaggg attcgaaccc ttgcgccagt tacccgacct aacgatttag caaaccgtcc
      301 tcttcagcct cttgagtaat tctccaatt
//
LOCUS       DAVBCA010000138          310 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.138, whole genome shotgun sequence.
ACCESSION   DAVBCA010000138 DAVBCA010000000
VERSION     DAVBCA010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 310)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 310)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..310
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.138"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(163..236)
                     /locus_tag="VQU19_002116"
     tRNA            complement(163..236)
                     /locus_tag="VQU19_002116"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(200..202),aa:Asn,seq:gtt)
BASE COUNT          102 a           71 c           48 g           89 t
ORIGIN      
        1 ctgttcgctc acaataagag agaacttttt tacgaaaatc tattgaatat gccataaaaa
       61 gattatacca cattgtgtac tatttttggt tcattttact ataacacgaa atagattatt
      121 attacataac aaaaaagagg tctaaacctc ttaactaaat tactccgcca gtaggactcg
      181 aacctacgac atcatgatta acagtcatgc gctactacca actgagctat ggcggattaa
      241 agctaagcga cttccctatc tcacaggggg caacccccaa ctacttccgg cgttctaggg
      301 cttaacttct
//
LOCUS       DAVBCA010000139          299 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.139, whole genome shotgun sequence.
ACCESSION   DAVBCA010000139 DAVBCA010000000
VERSION     DAVBCA010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 299)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 299)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..299
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.139"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..223
                     /locus_tag="VQU19_002117"
     CDS             <1..223
                     /locus_tag="VQU19_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2481282.1"
                     /translation="QAQTPRKSSKLKPLTAEDKACNHVLSKERSKVENIFAKVKTLKM
                     FSTTYRNHRKRFGLRMNLIVGIINHELGF"
BASE COUNT          109 a           52 c           54 g           84 t
ORIGIN      
        1 tcaagcacaa actccacgta aatccagcaa actcaagccg ctaacagctg aagataaagc
       61 ctgtaaccat gtgctatcta aggagagaag caaggttgag aacatctttg ccaaagtaaa
      121 aacgcttaaa atgttttcaa caacctatcg aaatcatcgt aaacgcttcg gattacggat
      181 gaatttgatt gttggtatta tcaatcatga actaggattc tagttttgca ggaagtctat
      241 tatcaaaaat accatcagga ttatataaga ttgatacagg aaaagtttta ttttatggt
//
LOCUS       DAVBCA010000140          288 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.140, whole genome shotgun sequence.
ACCESSION   DAVBCA010000140 DAVBCA010000000
VERSION     DAVBCA010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 288)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 288)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..288
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.140"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..>288
                     /locus_tag="VQU19_002118"
     CDS             <1..>288
                     /locus_tag="VQU19_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HET2481283.1"
                     /translation="NRVKAAKKVPLDRMPYNLQYTVEVKNGSLIIPHYDHYHNIKFEW
                     FDEGLYEAPKGYTLEDLLATVKYYVEHPNERPHSDNGFGNASDHVQRNKNG"
BASE COUNT           93 a           59 c           59 g           77 t
ORIGIN      
        1 caaccgcgtg aaagcagcta agaaggtgcc acttgatcgt atgccttaca atcttcaata
       61 tactgtagaa gtcaaaaacg gtagtttaat catacctcat tatgaccatt accataacat
      121 caaatttgag tggtttgacg aaggccttta tgaggcacct aaggggtata ctcttgagga
      181 tcttttggcg actgtcaagt actatgtcga acatccaaac gaacgtccgc attcagataa
      241 tggttttggt aacgctagcg accatgttca aagaaacaaa aatggtca
//
LOCUS       DAVBCA010000141          277 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.141, whole genome shotgun sequence.
ACCESSION   DAVBCA010000141 DAVBCA010000000
VERSION     DAVBCA010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 277)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 277)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..277
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.141"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..>277
                     /locus_tag="VQU19_002119"
     CDS             <1..>277
                     /locus_tag="VQU19_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET2481284.1"
                     /translation="QRIIEAIESALEKVDEYAESYNRLEQLDKEFPDKLKKSILQYAM
                     QGKLVEQDPNDESVEVLLEKIRAEKQKLFEEGKIKKKDLDISIVSQG"
BASE COUNT          126 a           37 c           47 g           67 t
ORIGIN      
        1 aacaacgcat aatagaagca atcgaatcag ctttagaaaa agtagatgaa tatgctgaaa
       61 gttataatag actagaacag ctagataaag aatttccaga taaactaaaa aaatctattc
      121 ttcaatatgc tatgcaagga aaattagttg aacaagaccc aaatgatgaa tcagtcgaag
      181 ttttacttga aaaaatacga gcagaaaaac aaaaactctt tgaagaaggc aagattaaaa
      241 agaaagattt ggacatttct attgtttccc aaggaga
//
LOCUS       DAVBCA010000142          275 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.142, whole genome shotgun sequence.
ACCESSION   DAVBCA010000142 DAVBCA010000000
VERSION     DAVBCA010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 275)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 275)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..275
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.142"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(1..275)
                     /locus_tag="VQU19_002120"
                     /pseudo
     CDS             complement(1..275)
                     /locus_tag="VQU19_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="internal stop; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT           88 a           45 c           57 g           85 t
ORIGIN      
        1 tgaaaaagca agagctgata gagttgatag tggtgtttca agtcttccga ataactcaaa
       61 agcttgttta aaatctcttt attggttcaa tgcatacgaa aagtaggacg ataaaaatgt
      121 ttatcactca gtttacgact atcctgttga atgagtttcc agtagcgctt gatagccttg
      181 tattcatggg attttcgatg aaactgattt atgatttgaa cacgcacacg actcatagca
      241 cggctaagat gttgtacaat gtgaaagcga tccaa
//
LOCUS       DAVBCA010000143          272 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.143, whole genome shotgun sequence.
ACCESSION   DAVBCA010000143 DAVBCA010000000
VERSION     DAVBCA010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 272)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 272)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..272
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.143"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(1..272)
                     /locus_tag="VQU19_002121"
                     /pseudo
     CDS             complement(1..272)
                     /locus_tag="VQU19_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
BASE COUNT           75 a           72 c           48 g           77 t
ORIGIN      
        1 atacttgagg ctgtattcaa ttgcccttcc tagttttgaa cccgataaaa ctgactgacg
       61 ccggcaccaa gcaaagaaat cttccattag gttggagctc ttcttgacgt ttctgtagtc
      121 gttcatcagc tggcaaagcc tcccagtctc tttccaagaa aaataactga tcacaataag
      181 ctaaaccttt agctcctaag gatgatttat ccgcttgctt gggggtcgct tcaaaaaact
      241 tccttctcac atgcgcccaa catccaacaa gt
//
LOCUS       DAVBCA010000144          260 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064141-rid20185593.denovo.144, whole genome shotgun sequence.
ACCESSION   DAVBCA010000144 DAVBCA010000000
VERSION     DAVBCA010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064141
            Sequence Read Archive: ERR373941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 260)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 260)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980389.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980389.1
            Genome Coverage       :: 219x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,122
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,950
            CDSs (with protein)               :: 1,950
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 61 of 136
            Pseudo Genes (incomplete)         :: 69 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 25 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..260
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064141-rid20185593.denovo.144"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..>260)
                     /locus_tag="VQU19_002122"
     CDS             complement(<1..>260)
                     /locus_tag="VQU19_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2481285.1"
                     /translation="IVQHLSRAMSRVRVQIMNQFHRKSHEYKAIKRYWKLIQQDSRKL
                     SDKRFYRPTFRMHLTNKEILNKLLSYSEDLKHHYQLYQLLLF"
BASE COUNT           80 a           42 c           56 g           82 t
ORIGIN      
        1 tgaaaaagca agagttgata gagttgatag tggtgtttca agtcttccga ataactcaaa
       61 agcttgttta aaatctcttt attggttaag tgcatacgaa aagtaggacg ataaaaacgt
      121 ttatcactca gtttacggct atcctgttga atgagtttcc agtagcgctt gatagccttg
      181 tattcatggg attttcgatg aaactgattc atgatttgga cacgcacacg actcatagca
      241 cggctaagat gttgtacaat
//
